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Journal articles on the topic '001/2024'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Kurdi, Kurdi, and Cut Zulfahnur Syafitri. "Analysis Of The Use Of The Dispute Resolution Clause Through Arbitration (Article 79.3) In The Peunaga Cut Ujong Road Construction Agreement Kab. West Aceh Number 001/Pupr-Abar/2024." Journal of Law, Politic and Humanities 4, no. 5 (2024): 1429–37. https://doi.org/10.38035/jlph.v4i5.495.

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The real impact of the existence of changes in Article 88 of Law No. 18 of 1999 with Law No. 2 of 2017 concerning Construction Services can be seen in construction service agreements including the Peunaga Cut Ujong Road Development Agreement, West Aceh District No. 001/PUPR-ABAR/2024 whose agreement clause states that the parties agree to resolve disputes through BANI. From here, problems are formulated, namely: First, what are the provisions regarding the arbitration clause in the Peunaga Cut Ujong Road Development Agreement of West Aceh District Number 001/PUPR-ABAR/2024. Second, Does the pr

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Johnson, Robert G. "ROBERT G. JOHNSON (2024) Devonian Harpetidae from the central and eastern Anti-Atlas, Morocco. Zootaxa, 5450 (1): 001-185." Zootaxa 5477, no. 5 (2024): 600. https://doi.org/10.11646/zootaxa.5477.5.7.

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Johnson, Robert G. (2024): ROBERT G. JOHNSON (2024) Devonian Harpetidae from the central and eastern Anti-Atlas, Morocco. Zootaxa, 5450 (1): 001-185. Zootaxa 5477 (5): 600-600, DOI: 10.11646/zootaxa.5477.5.7

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Pearson, Antonia, Haryana Dhillon, Jill Chen, et al. "Abstract P1-04-14: Vaginal oestradiol pessaries for the treatment of genitourinary symptoms in women with early breast cancer: a single arm phase 2 study (OVGUS)." Clinical Cancer Research 31, no. 12_Supplement (2025): P1–04–14—P1–04–14. https://doi.org/10.1158/1557-3265.sabcs24-p1-04-14.

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Abstract Introduction: Genitourinary syndrome of menopause is common in breast cancer survivors. Guidelines recommend first-line non-hormonal vaginal treatments, and if these fail, consideration of vaginal oestrogens. Yet, product labels warning against their use continues and fear of cancer recurrence (FCR) is a perceived barrier to use. Purpose: We aimed to determine the feasibility of a 12-week course of vaginal oestrogen in women with early breast cancer (EBC) on aromatase inhibitors (AIs). Methods: We conducted a single arm phase 2 feasibility study of oestradiol (10mcg Vagifem Low™) admi

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Zhao, Kehao, Yong Zhag, Yufang Shi, and Jian Chen. "Abstract LB428: Discovery of KY-001:A Direct Inhibitor of TEAD-YAP Protein-Protein Interaction for the Treatment of Advanced Solid Tumors with Abnormal Hippo Signaling Pathway." Cancer Research 84, no. 7_Supplement (2024): LB428. http://dx.doi.org/10.1158/1538-7445.am2024-lb428.

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Abstract Background:The Hippo signaling is an important pathway that plays a crucial role in the regulation of numerous biological processes. The binding of YAP/TAZ transcriptional coactivators to TEAD proteins is the core of Hippo signaling in regulating the expression of a variety of genes that mediate many cellular functions. Abnormalities of Hippo signaling including mutation deficiency, fusion and YAP/TAZ overexpression are often found in solid tumors associated with excessive proliferation, drug resistance, or tumor immune evasion. Blocking the Hippo transcription activation, particularl

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MANZATO, Welington Junior Jorge, Marcelo Negri SOARES, Jarbas Rodrigues Gomes CUGULA, and Luiz Fernando de Andrade VIDOTO. "PERSONALITY RIGHTS AND THE LAW Nº 15.001/2024: CONFLICTS AND CONVERGENCES IN THE SCHOOL ENVIRONMENT." Boletim de Conjuntura (BOCA) 21, no. 61 (2025): 249–80. https://doi.org/10.5281/zenodo.14994560.

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The general objective of this paper is to analyze the impact of Law 15,001/2024 on personality rights in the educational context, with an emphasis on the rights to privacy, honor, and image. The specific objectives are to understand the concept and characteristics of personality rights, address the main impacts of the aforementioned law on the protection of these rights, discuss the necessary balance between transparency and data protection, examine the strengthening of social control, and analyze the challenges in implementing the legislation in light of these rights. The methodology adopted

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Uiblein, Franz, Jeffrey T. Williams, Nicolas Bailly, Tuan A. Hoang, and P. Thomas Rajan. "Four new goatfishes (Upeneus, Mullidae, Mulliformes) from the Asian Indo-Pacific with a list of valid goatfish species and remarks on goatfish diversity." Cybium 48, no. 2 (2024): 135–60. https://doi.org/10.26028/cybium/2024-001.

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Uiblein, Franz, Williams, Jeffrey T., Bailly, Nicolas, Hoang, Tuan A., Rajan, P. Thomas (2024): Four new goatfishes (Upeneus, Mullidae, Mulliformes) from the Asian Indo-Pacific with a list of valid goatfish species and remarks on goatfish diversity. Cybium 48 (2): 135-160, DOI: 10.26028/cybium/2024-001, URL: http://dx.doi.org/10.5281/zenodo.13863108

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Reid, Tony R., Bryan Oronsky, Jeannie Williams, Scott Caroen та Anthony Conley. "TGF-β trap of AdAPT-001 turns up the heat on tumors and turns down checkpoint blocker resistance". Journal for ImmunoTherapy of Cancer 12, № 10 (2024): e009613. http://dx.doi.org/10.1136/jitc-2024-009613.

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At the ASCO 2024 meeting, Anthony P Conley, coauthor on this editorial, presented promising data from the phase 1/2 clinical trial called BETA PRIME (ClinicalTrials.govNCT04673942) with AdAPT-001 plus a checkpoint inhibitor (CI). All participants gave informed consent to participate in BETA PRIME before taking part. AdAPT-001 is an oncolytic adenovirus that expresses a transforming growth factor beta (TGF-β) trap to neutralize active TGF-β. This editorial proposes that the TGF-β trap of AdAPT-001 reverses the immunosuppressive environment of tumor cells, and thus makes these tumors susceptible

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YATOO, SUHAIB FIRDOUS, AIJAZ AHMAD WACHKOO, KAVYA G. PILLAI, and CHRIS M. COHEN. "SUHAIB FIRDOUS YATOO, AIJAZ AHMAD WACHKOO, KAVYA G. PILLAI & CHRIS M. COHEN (2024) Catalog of the Robber Flies of India (Diptera: Asilidae). Zootaxa, 5509 (1): 001-088." Zootaxa 5514, no. 6 (2024): 600. https://doi.org/10.11646/zootaxa.5514.6.10.

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YATOO, SUHAIB FIRDOUS, WACHKOO, AIJAZ AHMAD, PILLAI, KAVYA G., COHEN, CHRIS M. (2024): SUHAIB FIRDOUS YATOO, AIJAZ AHMAD WACHKOO, KAVYA G. PILLAI & CHRIS M. COHEN (2024) Catalog of the Robber Flies of India (Diptera: Asilidae). Zootaxa, 5509 (1): 001-088. Zootaxa 5514 (6): 600-600, DOI: 10.11646/zootaxa.5514.6.10, URL: https://doi.org/10.11646/zootaxa.5514.6.10

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Ankudavičius, Vytautas. "Nesmulkiųjų ląstelių plaučių vėžiu sergančiųjų mikrobiomas, imuninių žymenų raiška bei kriobiopsijos diagnostinė vertė." Pulmonology and allergology 8, no. 2 (2024): 144–52. http://dx.doi.org/10.37499/pia.1483.

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2024 m. gegužės 23 d. Lietuvos sveikatos mokslų universiteto viešajame Lietuvos sveikatos mokslų universiteto Medicinos mokslo krypties tarybos posėdyje Vytautas Ankudavičius sėkmingai apgynė daktaro disertaciją „Nesmulkiųjų ląstelių plaučių vėžiu sergančiųjų mikrobiomas, imuninių žymenų raiška bei kriobiopsijos diagnostinė vertė“. Disertacija rengta 2019–2023 m. Lietuvos sveikatos mokslų universiteto Medicinos fakulteto Pulmonologijos klinikoje. Šiame straipsnyje pateikiami pagrindiniai disertacijos rezultatai. Mokslinis vadovas:prof. dr. Marius Žemaitis (Lietuvos sveikatos mokslų universitet

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Palačionytė, Jolita. "Eozinofilų potipių proliferacinis aktyvumas ir imuninio atsako ypatumai sergant 2 tipo astma." Pulmonology and allergology 8, no. 2 (2024): 153–65. http://dx.doi.org/10.37499/pia.1484.

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2024 m. rugpjūčio 13 d. Lietuvos sveikatos mokslų universiteto viešajame medicinos Lietuvos sveikatos mokslų universiteto Medicinos mokslo krypties tarybos posėdyje Jolita Palačionytė sėkmingai apgynė daktaro disertaciją „Eozinofilų potipių proliferacinis aktyvumas ir imuninio atsako ypatumai sergant 2 tipo astma“. Disertacija rengta 2019–2023 m. Lietuvos sveikatos mokslų universiteto Medicinos fakulteto Pulmonologijos klinikoje. Šiame straipsnyje pateikiami pagrindiniai disertacijos rezultatai. Mokslinis vadovas:prof. dr. Kęstutis Malakauskas (Lietuvos sveikatos mokslų universitetas, medicino

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Eriten, Semih. "Retrospective analysis of admissions to the emergency department of an urban state hospital: A cross-sectional study of 5,279,630 patient visits (2019–2024)." Medicine 104, no. 9 (2025): e41669. https://doi.org/10.1097/md.0000000000041669.

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The study aims to comprehensively evaluate the demographic data, diagnostic spectrum, and temporal changes of 5.3 million patients in a state hospital emergency department in an urban area of Istanbul between 2019 and 2024. Data of 5,279,033 patients admitted to Sultanbeyli State Hospital Emergency Department between 2019 and 2024 were retrospectively analyzed. Sociodemographic characteristics, diagnoses, time of presentation, and seasonal variables of 879,839 average annual admissions (minimum: 653,746, maximum: 1068,504) were evaluated. Upper respiratory tract diseases accounted for 26.7% to

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12

Huseynova, Lala. "Curliness Of Peach Leaves In The Western Part Of Azerbaijan." Acta Biologica Universitatis Daugavpiliensis 24, no. 1 (2024): 1–8. https://doi.org/10.59893/abud.24(1).001.

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Huseynova, Lala (2024): Curliness Of Peach Leaves In The Western Part Of Azerbaijan. Acta Biologica Universitatis Daugavpiliensis 24 (1): 1-8, DOI: 10.59893/abud.24(1).001, URL: https://du.lv/zinatne/instituti/dzivibas-zinatnu-un-tehnologiju-instituts/zinatniskie-izdevumi/acta-biologica-universitatis-daugavpiliensis/acta-biologica-universitatis-daugavpiliensis-arhivs/acta-biologica-universitatis-daugavpiliensis-volume-24-no-1-2024/curliness-of-peach-leaves-in-the-western-part-of-azerbaijan/

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Zhang, Lei, Junshuai Ma, Shaobo Qu, Zhangxin Cui, and Mingfu Cao. "Analysis of changes in respiratory tract infections in a tertiary grade A hospital in Zhangjiakou area from 2018 to 2024." Medicine 104, no. 29 (2025): e43435. https://doi.org/10.1097/md.0000000000043435.

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We aimed to analyze the epidemiological characteristics and pathogen trends of common respiratory infections in a tertiary hospital in Zhangjiakou from 2018 to 2024. We retrospectively studied patients who underwent screening for 11 common respiratory pathogen antibodies at the First Affiliated Hospital of Hebei North University between January 1, 2018, and December 31, 2024. Serum-specific Immunoglobulin M antibodies were detected using indirect immunofluorescence assays, and annual data from 2018 to 2024 were compared. Among 35,665 patients, 10,531 (29.53%) were positive for at least 2 patho

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Telnov, Dmitry. "A new, peculiarly coloured Anthicomorphus Lewis, 1895 (Coleoptera: Anthicidae) from southern Vietnam." Baltic Journal of Coleopterology 24, no. 1 (2024): 1–7. https://doi.org/10.59893/bjc.24(1).001.

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Telnov, Dmitry (2024): A new, peculiarly coloured Anthicomorphus Lewis, 1895 (Coleoptera: Anthicidae) from southern Vietnam. Baltic Journal of Coleopterology 24 (1): 1-7, DOI: 10.59893/bjc.24(1).001, URL: http://dx.doi.org/10.5281/zenodo.13200353

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Jo, Ennuri. "The Underwater Eye, Margaret Cohen (2022) Oceaning, Adam Fish (2024)." Journal of Environmental Media 6, no. 1 (2025): 99–107. https://doi.org/10.1386/jem_00139_5.

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Review of: The Underwater Eye, Margaret Cohen (2022) Princeton, NJ: Princeton University Press, 344 pp., ISBN 978-0-69119-797-5, h/bk, $39.00 Oceaning, Adam Fish (2024) Durham, NC: Duke University Press, 248 pp., ISBN 978-1-47803-001-0, p/bk, $26.95

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PEDRO, H. PRETE, and D. BRESCOVIT ANTONIO. "Taxonomic revision of the orb weaving spider genus Plato Coddington, 1986 (Araneae: Theridiosomatidae) with the description of three new species. Zootaxa, 5471 (1): 001-032." Zootaxa 5474, no. 5 (2024): 600. https://doi.org/10.11646/zootaxa.5474.5.10.

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PEDRO H. PRETE, ANTONIO D. BRESCOVIT (2024): Taxonomic revision of the orb weaving spider genus Plato Coddington, 1986 (Araneae: Theridiosomatidae) with the description of three new species. Zootaxa, 5471 (1): 001-032. Zootaxa 5474 (5): 600-600, DOI: 10.11646/zootaxa.5474.5.10

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Li, Zhentian, Qipeng Fan, Mingming Gao, et al. "Abstract 4562: Activity of PARP1-selective inhibitor SNV-001 in models of HRD cancers as monotherapy and in combination." Cancer Research 84, no. 6_Supplement (2024): 4562. http://dx.doi.org/10.1158/1538-7445.am2024-4562.

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Abstract Current FDA approved poly (ADP-ribose) polymerase inhibitors (PARPi) inhibit both PARP1 and PARP2. Genetic studies indicate that loss of PARP1 is synthetic lethal with homologous recombination deficiency (HRD), including BRCA1/2 mutations, and PARP2 depletion may be linked to hematologic toxicity. To date, no first generation PARPi has been successfully combined with standard of care (SoC) agents in the clinic without significant reduction in dosing intensity because of overlapping toxicities. A selective inhibitor could potentially improve the therapeutic index and provide additional

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Falcon, Arlene, Grace Cabanela, Isa June Pagas, Jingle Durias, and Hazel Jade Huliganga. "Cognitive and Environmental Factors Affecting Attention Span in Grade 2 Pupils." Psychology and Education: A Multidisciplinary Journal 42, no. 3 (2025): 509–13. https://doi.org/10.70838/pemj.420307.

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Attention span is a critical component of learning, particularly in early childhood education. This study examined the relationship and influence of cognitive development and environment on the attention span of Grade 2 pupils in Region XI, Philippines. Using a non-experimental, quantitative correlational design, data were gathered from 74 purposively selected Grade 2 pupils during the school year 2024–2025. The study used adapted and validated instruments to assess cognitive development (mean = 4.25, SD = 0.42), environment (mean = 4.27, SD = 0.38), and attention span (mean = 4.47, SD = 0.36)

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Kim, Seong Kyong, Ja Young Min, Ji Woo Kim, et al. "The Effect of Empathy Ability and Communication Ability on Satisfaction with One’s Major in Nursing Students." Korean Association For Learner-Centered Curriculum And Instruction 25, no. 13 (2025): 97–106. https://doi.org/10.22251/jlcci.2025.25.13.97.

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Objectives This study was intended to evaluate the effect of empathy ability and communication ability on satisfaction with one’s major of nursing students. Methods The study participants were 130 3rd and 4th year nursing students at H University in South Chungcheong Province. Data were collected from September 25 to October 11, 2024. Data collected were analyzed using the SPSS WIN 30.0 program by t-test, ANOVA, Pearson’s correlation coefficients, and multiple regression analysis. Results Empathy ability showed a significantly negative correlation with communication ability(r=-.64, p<.001)

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Ningrum, Sevti Prana, Eka Ardianto Iskandar, and Herli Antoni. "Tinjauan Yuridis Putusan Bawaslu Kota Bogor Nomor: 001/LP/ADM.PP/BWSL.KOTABOGOR/13.04/III/2024." Journal of Law, Education and Business 3, no. 1 (2025): 730–36. https://doi.org/10.57235/jleb.v3i1.5970.

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Pemilu adalah arena kompetisi untuk mengisi jabatan-jabatan politik di pemerintahan yang didasarkan pada pilihan formal dari warga negara yang memenuhi syarat. Peserta Pemilu dapat berupa perseorangan dan partai politik tetapi yang paling utama adalah partai politik. Sifat penelitian yang penulis terapkan adalah deskriptif analitis, artinya bahwa pembahasan dilakukan dengan cara menyajikan dan menjelaskan data secara lengkap, kemudian dianalisis dengan mengunakan teori-teori hukum serta perundang-undangan yang berlaku. Jenis penelitian yang penulis gunakan adalah penelitian Yuridis Normatif, y

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Rukmane-Bārbale, Anita, Dale Ann Acal, and Alma B. Mohagan. "Four new species of the genus Homalocyrtus Heller, 1912 (Coleoptera: Curculionidae: Pachyrhynchini) from the Philippines." Baltic Journal of Coleopterology 24, no. 2 (2024): 115–29. https://doi.org/10.59893/bjc.24(2).001.

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Rukmane-Bārbale, Anita, Acal, Dale Ann, Mohagan, Alma B. (2024): Four new species of the genus Homalocyrtus Heller, 1912 (Coleoptera: Curculionidae: Pachyrhynchini) from the Philippines. Baltic Journal of Coleopterology 24 (2): 115-129, DOI: 10.59893/bjc.24(2).001, URL: http://dx.doi.org/10.5281/zenodo.14657376

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Yeo, So-Young, Mohamed Farh, InSuk Sohn, Seok-Hyung Kim, and Keun-Woo Lee. "Abstract LB322: ARC2-001, a CAF-targeting drug exhibits strong anticancer effect in in vivo setting." Cancer Research 84, no. 7_Supplement (2024): LB322. http://dx.doi.org/10.1158/1538-7445.am2024-lb322.

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Abstract For more effective tumor growth suppression, a combinatorial treatment of CAF-targeting agent and other well-validated therapies such as chemotherapy, radiotherapy, and immune checkpoint therapy should be considered. Thus, we hypothesized that co-administration of the CAF-targeting drug, ARC2-001 (the in vitro-approved CAF-targeting candidate) and clinically practiced anticancer drugs could be useful strategy for treating under clinical settings. However, it is essentially important to evaluate this using well-established pre-clinical models. We thoroughly verified the anticancer effe

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Din, Sirajud, Raima Adeel, Adeel Alvi, and Waqar Sadiq. "Assessing the Effectiveness of Financial Literacy Programs in Pakistani Universities." Journal of Asian Development Studies 13, no. 3 (2024): 1760–69. http://dx.doi.org/10.62345/jads.2024.13.3.141.

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This study examined the effectiveness of financial literacy programs across eight Pakistani universities, analyzing data from 450 undergraduate students during 2023-2024. Employing a mixed-methods approach combining quantitative surveys and qualitative assessments, the research investigated changes in students' financial knowledge, attitudes, and behaviours through structured interventions. Statistical analysis revealed significant improvements in financial knowledge scores (p < .001), with interactive teaching methods showing superior outcomes (mean difference = 2.6, SD = 0.15) compared to

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Nadeak, Erpina Santi Meliana. "Pemberian Edukasi Kepada Ibu Rumah Tangga tentang Pengelolaan Sampah Rumah Tangga di Desa Mantang Besar RT 001 RW 001 Kabupaten Bintan Tahun 2024." Jurnal Salam Sehat Masyarakat (JSSM) 6, no. 01 (2024): 30–37. https://doi.org/10.22437/jssm.v6i01.39582.

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Kim, Soon Ock. "Analysis of Factors Influencing Nursing Students' Confidence in Performing Core Basic Nursing Skills." Forum of Public Safety and Culture 37 (December 31, 2024): 15–28. https://doi.org/10.52902/kjsc.2024.37.15.

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This study is a descriptive research study conducted to confirm the factors influencing on nursing students' confidence in performing core basic nursing skills and use it as evidence to find ways to improve confidence in performing core basic nursing skills. The subjects were 179 Nursing student and data were collected from June 20 to 30, 2024. Data were analyzed t-test, ANOVA, Scheffe’s test, Pearson correlation coefficients and Multiple linear regression analysis using the SPSS 29.0. Confidence in performing core basic nursing skills includes critical thinking disposition(r=.528, p<.001),

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Kim, Yunyoung, Eun-Jin Lim, and Ka-Ka Shim. "Impact of Leisure Satisfaction and Social Health on Self-Rated Health Among Older Adults." Korea Industrial Technology Convergence Society 29, no. 4 (2024): 17–28. https://doi.org/10.29279/jitr.k.2024.29.4.17.

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This study aimed to explorethe relationships among leisure satisfaction, social health, and subjective health in older adults. It investigated how social interactions through leisure activities contribute to emotional stability, stress reduction, decreased depression, and overall well-being. Data were collected in June and July 2024 from 214 seniors aged 60 and older and residing in G City. Multiple regression analysis revealed significant correlations between leisure satisfaction and social health (r=0.463, p<.001), leisure satisfaction and self-rated health (r=0.355, p<.001), and socia

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Nisak, Umi Khoirun, Laili Rahmatul Ilmi, Nabila Insyira Natasya, Citra Anggun Kinanthi, and Cholifah Cholifah. "TRANSFORMING MEDICAL RECORDS INTO ACTIONABLE INSIGHTS THROUGH DATA VISUALIZATION DASHBOARDS." Journal of Social Comunity Services (JSCS) 2, no. 1 (2024): 34–41. https://doi.org/10.61796/jscs.v2i1.257.

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Objective: This community service aimed to educate healthcare workers at Aisyiyah Pandaan Inpatient Clinic on the process of medical record data, fostering data-driven decision-making in patient care. Method: In October 2024, a training program was conducted for 20 healthcare workers, focusing on medical record data analysis, interpretation, and presentation. Participants were trained on how to utilize medical data to support clinical decisions. Results: The training program led to a significant improvement in the participants' knowledge and abilities in medical record data analysis. The resul

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Balodis, Aleksandrs, and Dmitry Telnov. "Perilampus Aeneus (Rossius, 1790) (Hymenoptera: Perilampidae) Confirmed In Latvia And The Baltic States For The First Time In A Century." Acta Biologica Universitatis Daugavpiliensis 24, no. 2 (2024): 157–63. https://doi.org/10.59893/abud.24(2).001.

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Balodis, Aleksandrs, Telnov, Dmitry (2024): Perilampus Aeneus (Rossius, 1790) (Hymenoptera: Perilampidae) Confirmed In Latvia And The Baltic States For The First Time In A Century. Acta Biologica Universitatis Daugavpiliensis 24 (2): 157-163, DOI: 10.59893/abud.24(2).001, URL: https://du.lv/en/research/institutes/institute-of-life-sciences-and-technologies/issued-journal/acta-biologica-universitatis-daugavpiliensis/acta-biologica-universitatis-daugavpiliensis-archives/acta-biologica-universitatis-daugavpiliensis-volume-24-no-2-2024/perilampus-aeneus-rossius-1790-hymenoptera-perilampidae-confir

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Helsa Nasution, M. Agung Rahmadi, Luthfiah Mawar, and Nurzahara Sihombing. "Efektivitas Cognitive Behavioral Therapy (CBT) pada Konteks Trauma Perang Timur Tengah." Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran 3, no. 2 (2025): 247–69. https://doi.org/10.55606/termometer.v3i2.4955.

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This study evaluates the effectiveness of culturally adapted Cognitive Behavioral Therapy (CBT) in the treatment of war trauma in the Middle East through an analysis of 47 studies involving a total of 4,628 participants from 2000 to 2024. The findings indicate that culturally informed CBT interventions have produced a significant therapeutic effect (g = 0.82, 95% CI [0.71, 0.93], p < .001) with a moderate level of heterogeneity (I² = 68%). Furthermore, culturally adapted CBT has been shown to reduce symptoms of Post-Traumatic Stress Disorder (PTSD) by 43.2% (d = 1.24, p < .001), anxiety

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Lestari, Dewi Intan, and Masluroh Masluroh. "Faktor-Faktor yang Berhubungan dengan Pemanfaatan Buku Kia pada Ibu Hamil di Posyandu Desa Sukahaji Kecamatan Sukawening Kabupaten Garut." MAHESA : Malahayati Health Student Journal 5, no. 1 (2024): 148–61. https://doi.org/10.33024/mahesa.v5i1.16380.

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ABSTRACT Maternal death is caused by two factors, namely direct causes and indirect causes. The direct causes of maternal death are closely related to medical, obstetric complications during pregnancy, childbirth and postpartum. Meanwhile, indirect causes of maternal death can be caused by congenital diseases suffered by pregnant women or diseases that arise during pregnancy which do not have direct obstetric consequences, but these diseases are exacerbated by the physiological effects of pregnancy. Utilization of KIlA bellrtuljulan bulkul ulntulk improves health in the family environment espe

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Lee, Ji Eun, and Yun Ra Hur. "The Influence of Problem Solving Ability, Self Directed Learning Ability and Deep Approaches to Learning on Academic Achievement in Nursing Student: a focus on Project Based Learning." Korean Association For Learner-Centered Curriculum And Instruction 24, no. 22 (2024): 983–91. http://dx.doi.org/10.22251/jlcci.2024.24.22.983.

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Objectives This study aimed to provide fundamental data for improving academic achievement by examining the impact of nursing students' problem solving ability, self directed learning ability, and deep learning approach on academic achievement through the application of project based learning(PjBL). Methods This study is a descriptive correlational study conducted through a self-reported survey aimed at identifying the effects of problem-solving ability, self-directed learning ability, and deep learning approach on academic achievement among nursing students. The study participants were 114 se

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Ya’u Usman, Abdullahi, and Saidu Ibrahim Halidu. "A Quantitative Study of Nigerian Consumers’ Perceptions of Inflation and its Impact (2023–2024)." International Journal of Research and Innovation in Social Science IX, no. V (2025): 3217–27. https://doi.org/10.47772/ijriss.2025.905000250.

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This study investigates Nigerian consumers’ perceptions of inflation and its impact on household welfare, drawing on data from an online survey administered via WhatsApp and Facebook between 23 July and 4 August 2024. A total of 163 valid responses from adult Nigerians across diverse demographic groups were analysed. Composite indices were constructed for perceived inflation (mean = 4.21 on a 5-point scale), coping strategies (mean = 2.87 on a 4-point scale), and welfare impact (mean = 3.78 on a 5-point scale). Inferential analyses revealed that female respondents reported significantly higher

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Tekeoglu, Senem. "Comprehensive analysis of rheumatic diseases, comorbidities, and mortality in geriatric population: Real-world data of 515 patients in a single rheumatology clinic." Medicine 103, no. 48 (2024): e40753. http://dx.doi.org/10.1097/md.0000000000040753.

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Rheumatic diseases present unique challenges in the elderly, with changes in the immune system contributing to varied clinical presentations. More individuals are now living with chronic diseases due to greater life expectancy, but there is a lack of real-world data about rheumatic diseases and comorbidities in older people. This study aimed to investigate disease types, comorbidities, treatments, and mortality in geriatric patients in comparison to non-geriatric patients at a rheumatology clinic. This retrospective observational cohort study reviewed the medical records of 2610 patients from

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SELIHEY, Pylyp. "LEXICAL STANDARDIZATION AND USAGE RECOMMENDATIONS THROUGH THE EYES OF AN ETYMOLOGIST (COMMENTS, REFLECTIONS, EVALUATIONS)." MOVOZNAVSTVO 337, no. 4 (2024): 3–24. http://dx.doi.org/10.33190/0027-2833-337-2024-4-001.

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The article addresses the issue of the professionalism of cultural-language recommendations, criteria for lexical standardization, and the assessment of words as acceptable or unacceptable, considering their origin — whether native or borrowed. In the context of the trend towards differentiation from the Russian language, the authors of cultural-linguistic recommendations urge avoiding linguistic units shared with Russian and replacing them with different equivalents. It is shown that this trend extends not only to genuine Russianisms but also to words of East Slavic, Common Slavic, and even I

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Zhang, Ting, Qiong Shi, Julia Kalashova, et al. "Abstract 5802: An orally available small molecule JMBI-001 elicits MYC-synthetic lethality and anti-tumor immunity by disabling MKLP2-mediated cellular processes." Cancer Research 84, no. 6_Supplement (2024): 5802. http://dx.doi.org/10.1158/1538-7445.am2024-5802.

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Abstract The MYC oncogene, a pivotal regulator of various cellular processes, is deregulated in approximately 70 % of human malignancies. Mitotic Kinesin-like Protein 2 (MKLP2) plays a versatile role in both interphase and mitosis and has emerged as a significant prognostic indicator and therapeutic target in cancer. The undruggability of MYC and the scarcity of MKLP2 inhibitors, however, have impeded clinical translation. Our development of JMBI-001, a potent and orally bioavailable small-molecule compound, overcomes these barriers. JMBI-001 elicits loss of function phenotypes in MKLP2 and a

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Conley, Anthony P., Tony Reid, Chris Larson, et al. "Abstract CT264: Improved clinical outcomes in patients received treatment beyond tumor progression with AdAPT-001 +/- a checkpoint inhibitor." Cancer Research 84, no. 7_Supplement (2024): CT264. http://dx.doi.org/10.1158/1538-7445.am2024-ct264.

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Abstract Background AdAPT-001 is an oncolytic adenovirus with a TGF-β trap. Pseudoprogression (PsP) or transient tumor enlargement from intense T cell infiltration was commonly observed with AdAPT-001 in immune competent mouse models. We evaluated progression-free survival (PFS) and overall survival (OS) in 36 treatment-resistant patients (pts) that received AdAPT +/- an ICI on a Phase 2 clinical trial. Methods RECIST1.1 assessment was performed every 8 weeks. PsP was defined as progressive disease (PD) on RECIST 1.1 with subsequent tumor regression during TBP. The decision to TBP was based on

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Oshida, Keiyu, Mikito Hirakata, Emi Tomikawa, et al. "Abstract 679: TXB-001 is an upgraded conjugated anthracycline that targets tumors with reduced risk of cardiotoxicity, hand-foot syndrome and alopecia." Cancer Research 84, no. 6_Supplement (2024): 679. http://dx.doi.org/10.1158/1538-7445.am2024-679.

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Abstract TXB-001 is a well-optimized N-(2-hydroxypropyl)methacrylamide copolymer-based conjugated pirarubicin (THP) and a novel candidate for developing anticancer drugs. It exhibits tumor-specific accumulation due to the enhanced permeability and retention effects and prolonged circulation time compared with free THP. Its hydrazone bond is dissociated under lower pH conditions, providing selective and rapid release of THP in acidic tumor environments. Therefore, TXB-001 is expected to have high efficacy and low toxicity. Anthracycline anticancer drugs have been widely used for the treatment o

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Dai, Dan-dan, Chun-yi Jia, Yi-ning Wang, Jing Ma, and Xin-yuan Bi. "Meticulous nursing care for coronary CT angiography: A systematic review and meta-analysis of randomized controlled trials." Medicine 103, no. 36 (2024): e39551. http://dx.doi.org/10.1097/md.0000000000039551.

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Background: This study aimed to investigate the effects of meticulous nursing care (MNC) for patients with coronary heart disease undergoing coronary CT angiography (CCTA). Methods: We conducted a comprehensive search of the Cochrane Library, PubMed, EMBASE, China National Knowledge Infrastructure, and Wangfang databases from inception to January 1, 2024. Randomized clinical trials (RCTs) evaluating the effects of MNC for CCTA were included. Outcomes assessed included self-rating anxiety scale (SAS), self-rating depression scale (SDS), overall satisfaction of nursing care (OSNC), examination t

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Ekaputra, Firdiawan. "Optimalisasi Aplikasi Quizwhizzer dalam Kegiatan Perkuliahan Terhadap Peningkatan Motivasi Belajar Mahasiswa." Indonesian Journal of Learning and Educational Studies 1, no. 2 (2023): 62–68. http://dx.doi.org/10.62385/ijles.v1i2.47.

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Motivasi belajar memegang peranan penting dalam keberhasilan mahasiswa dalam belajar. Penggunaan media yang kurang mampu membangkitkan semangat belajar dapat menjadikan motivasi belajar menjadi rendah dan berdampak pada tingkat keberhasilan belajar mahasiswa. Penerapan aplikasi quizwhizzer merupakan fokus penelitian untuk meningkatkan motivasi belajar mahasiswa. Tujuan dari penelitian ini adalah menguji optimalisasi aplikasi quizwhizzer dalam kegiatan perkuliahan terhadap peningkatan motivasi belajar mahasiswa pada mata kuliah Biokimia II kelas R-001. Penelitian ini merupakan penelitian kuasi

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Christopher, Gift Onyinye, and Candan Ozturk. "Integrating a Nurse-Led Sexual and Reproductive Health Program Among Adolescents Living With HIV in Nigeria: Randomized Controlled Trial." AIDS Education and Prevention 37, no. 3 (2025): 218–36. https://doi.org/10.1521/aeap.2025.37.3.218.

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This study examines the impact of a nurse-led sexual and reproductive health (SRH) intervention on the knowledge and attitudes of adolescents living with HIV (ALHIV). Using a randomized controlled trial design, 50 participants (25 control, 25 intervention) were recruited, with 47 completing the study between October 2023 and April 2024. The intervention group received four interactive sessions covering personal hygiene, contraceptive use, STI prevention, and risky behaviors. Baseline assessments showed no significant difference between groups (t =-1.411, p = .300). However, post-intervention a

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Goswami, Avijit, Sandeep Goyal, Kawaljit Singh, Princy Khurana, Barnali Deb, and Aditya Kulkarni. "Abstract 4484: Discovery of a potential first-in-class Za targeted small molecule inhibitor of ADAR1 p150 which demonstrates strong anti-tumor efficacy." Cancer Research 84, no. 6_Supplement (2024): 4484. http://dx.doi.org/10.1158/1538-7445.am2024-4484.

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Abstract Background: Adenosine deaminase, RNA specific (ADAR1), catalyzes the hydrolytic deamination of adenosine (A) to inosine (I) in double-stranded (ds) RNAs. ADAR1 has two isoforms: p110 in the nucleus and p150 in the cytoplasm. Both isoforms alter the coding and non-coding sections of self-dsRNA. The ADAR1 p150 isoform is expressed from an interferon (IFN)-response promoter and has a Z-DNA/Z-RNA binding domain at the N-terminus. ADAR1 has been implicated in promoting cell survival and resistance to immune response in several cancer types like multiple myeloma, breast, lung, liver, and sk

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Nurzahara Sihombing, M. Agung Rahmadi, Helsa Nasution, and Luthfiah Mawar. "Kontribusi Modal Sosial pada Resiliensi Mental Komunitas di Zona Konflik Timur Tengah." Jurnal Anestesi 3, no. 2 (2025): 127–48. https://doi.org/10.59680/anestesi.v3i2.1798.

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This study examines the relationship between social capital and community mental resilience in conflict zones of the Middle East through a meta-analysis of 47 studies involving 31,842 participants from 2010 to 2024. Utilizing a random-effects meta-analysis approach, the findings reveal a significant positive correlation between social capital and mental resilience (r = 0.64, p < .001, 95% CI [0.58, 0.70]).

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De Dreuzy, Edouard, Soha Reda El Sayed, Delphine Genin, et al. "Abstract 6322: CCTx-001 CAR T-cells targeting the AML specific antigen IL-1RAP show robust pre-clinical anti-tumor efficacy." Cancer Research 84, no. 6_Supplement (2024): 6322. http://dx.doi.org/10.1158/1538-7445.am2024-6322.

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Abstract Despite significant advancements in acute myeloid leukemia (AML) treatment, patients with relapsed/refractory (r/r) AML have limited therapeutic options. Novel approaches are urgently needed. CAR T-cell therapy has shown remarkable success in hematological malignancies. However, its application in AML has been hampered by the absence of highly AML-specific antigens, making current CAR T-cell AML therapies under development poorly tolerated and effective. This pre-clinical study introduces a novel CAR T-cell therapy, CCTx-001, specifically designed to target IL-1RAP, a 78-kDa transmemb

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Mima, Shinji, Monta Sakaki, Noriaki Kiya, Atsunari Kawashima, Norio Nonomura, and Chihaya Kakinuma. "Abstract 3329: Development of HM-001 as a therapeutic drug for non-muscle invasive bladder cancer." Cancer Research 84, no. 6_Supplement (2024): 3329. http://dx.doi.org/10.1158/1538-7445.am2024-3329.

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Abstract HM-001 is a drug containing sodium chlorite as the active ingredient that is being developed as a drug for non-muscle invasive bladder cancer (NMIBC), and is currently undergoing physician-led clinical trials. It has been discovered that sodium chlorite generates radicals in an acidic environment, and phosphatidylserine on the surface of tumor cells acts as a Lewis acid to generate radicals. HM-001, like other anticancer drugs and BCG, is intended to be injected into the bladder, retained, and then excreted. GLP studies using the same administration method has been completed, and no t

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Liu, Rongrong, Li Wang, Hui Xu та ін. "Updated Safety and Efficacy Results of RM-001, Autologous HBG1/2 Promoter-Modified CD34+ Hematopoietic Stem and Progenitor Cells, in Treating Transfusion-Dependent β-Thalassemia". Blood 144, Supplement 1 (2024): 4960. https://doi.org/10.1182/blood-2024-206549.

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Introduction : RM-001 is a novel non-viral cell therapy for β-hemoglobinopathies, which is designed to reactivate fetal hemoglobin (HbF) via ex vivo CRISPR-Cas9 gene-editing of autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) at the binding site of BCL11A on the promoter of the γ-globin genes (HBG1/2). Here we report that in both investigator initiated trial (IIT) and phase I trial, all the patients (pts) with transfusion-dependent β-thalassemia (TDT) achieved transfusion-free after RM-001 treatment. Methods: Both IIT (ChiCTR2100053406 and ChiCTR2100052858, n =7) and phase I tr

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Toy, Weiyi, Dipti Thakkar, Roberto Magallanes, et al. "Abstract 5796: A HER3 antibody that uniquely blocks the HER3 heterodimerization interface effectively inhibits tumor growth in pre-clinical models with potentially oncogenic HER3 mutations." Cancer Research 84, no. 6_Supplement (2024): 5796. http://dx.doi.org/10.1158/1538-7445.am2024-5796.

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Abstract HER3 activation, via NRG1 ligand-dependent and -independent heterodimerization with HER2 or EGFR, has been associated with tumor progression and acquired resistance to therapies in multiple indications. HER3 mutations, detected in around 3% of cancer cases, may drive oncogenic signaling, leading to rapid tumor growth. Currently, there are no approved targeted therapies for HER3 mutations. Through analysis of real-world data and structural modelling of HER3 heterodimers, we identified four common HER3 mutations located within or close to the dimerization interface of HER3, suggesting a

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Palomba, Maria Lia, Paolo F. Caimi, Matthew Mei, et al. "A Phase 1 Study to Evaluate the Safety and Tolerability of a Combination Autologous CD19 CAR T Cell Therapy (SYNCAR-001) and Orthogonal IL-2 (STK-009) in Subjects with Relapsed or Refractory CD19 Expressing Hematologic Malignancies (NCT05665062)." Blood 144, Supplement 1 (2024): 3453. https://doi.org/10.1182/blood-2024-202090.

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Background: CAR T cell therapy has demonstrated clinical efficacy in hematologic malignancies. However, their efficacy can be limited by compromised T cell effector function, proliferation, and persistence. Interleukin (IL)-2 is a potent T cell stimulator, but its therapeutic application is limited by toxicity. To provide a selective IL-2 signal, we developed a human orthogonal ligand/receptor system for cell therapy. SYNCAR-001 is an autologous CAR T cell co-expressing a CD19-28z CAR and a mutated IL-2 receptor beta (hoRβ). SYNCAR-001 is administered with STK-009, a pegylated IL-2 mutein that

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Zhang, Jing, Sun Min Lim, Mi Ra Yu, et al. "Abstract 6503: D3S-001, a second-generation GDP-bound KRAS G12C inhibitor, overcomes nucleotide cycling and demonstrates robust preclinical and clinical activities." Cancer Research 84, no. 6_Supplement (2024): 6503. http://dx.doi.org/10.1158/1538-7445.am2024-6503.

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Abstract First-generation KRAS G12C inhibitors [G12Ci(s)], such as sotorasib and adagrasib, are limited by the depth and duration of clinical responses. One potential explanation for their modest clinical activity is the dynamic “cycling” of KRAS between its GDP- and GTP-bound states, raising controversy whether targeting the GDP-bound form can fully block this oncogenic driver. We herein report D3S-001, a second-generation GDP-bound G12Ci with faster target engagement (TE) kinetics, depletes cellular active KRAS G12C at sub-nanomolar concentrations, overcomes nucleotide cycling, and demonstra

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Svoboda, Ondrej, Lukas Melecky, and Michaela Stanickova. "The nexus of a regional competitiveness and economic resilience: The evidence-based on V4+4 NUTS 2 regions." E+M Ekonomie a Management 27, no. 1 (2024): 6–23. http://dx.doi.org/10.15240/tul/001/2024-1-001.

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Economies have always been prone to economic downturns, industry shocks, currency crises, and the current COVID-19 epidemic crises, destabilising a region’s economic growth trajectory and pattern. By re-establishing economic ties both inside and outside regions, regional economies that have been disturbed by a shock may transition to a new growth trajectory. We examined the idea of competitiveness and resilience in a regional development context to answer why one region is more susceptible to economic shock than others and the competitive advantages and disadvantages of V4+4 countries. This ar

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Nguyen, Thach Ngoc, My Ha Tien Duong, and Diep Van Nguyen. "Natural resources and the underground economy: A cross-country study in ASEAN using Bayesian approach." E+M Ekonomie a Management 27, no. 2 (2024): 1–15. http://dx.doi.org/10.15240/tul/001/2024-2-001.

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The development of the underground economy can significantly affect a country’s economic indicators. Although there have been different studies on this phenomenon, many aspects of underground activities remain incompletely defined. Therefore, the current research aims to supplement the existing literature by analyzing the link between abundant natural resources and the scope of the underground economy. To accomplish this objective, we collected panel data from ten Association of Southeast Asian Nations (ASEAN) countries during the period 1991–2018. We then employed the Bayesian regression esti

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