Academic literature on the topic 'Advanced molecular testing'

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Journal articles on the topic "Advanced molecular testing"

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C. Huynh, Jasmine, Erin Schwab, Jingran Ji, et al. "Recent Advances in Targeted Therapies for Advanced Gastrointestinal Malignancies." Cancers 12, no. 5 (2020): 1168. http://dx.doi.org/10.3390/cancers12051168.

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The treatment of advanced gastrointestinal (GI) cancers has become increasingly molecularly driven. Molecular profiling for HER2 and PD-L1 status is standard for metastatic gastroesophageal (GEJ) cancers to predict benefits from trastuzumab (HER2-targeted therapy) and pembrolizumab (anti-PD-1 therapy), while extended RAS and BRAF testing is standard in metastatic colorectal cancer to predict benefits from epidermal growth factor receptor (EGFR)-targeted therapies. Mismatch repair (MMR) or microsatellite instability (MSI) testing is standard for all advanced GI cancers to predict benefits from
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Litton, Jennifer K., Harold J. Burstein, and Nicholas C. Turner. "Molecular Testing in Breast Cancer." American Society of Clinical Oncology Educational Book, no. 39 (May 2019): e1-e7. http://dx.doi.org/10.1200/edbk_237715.

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Molecular testing for genetic and genomic variation has become an integral part of breast cancer management. Patients with a family history of breast cancer or other tumors, bilateral breast cancers, or early-onset breast cancers warrant genetic testing to determine whether a hereditary cancer syndrome is present. The availability of PARP inhibitors—drugs that are selectively active in BRCA1/2-associated breast cancers—has created the need for hereditary cancer testing for all patients diagnosed with advanced breast cancer. Tumor genomic profiling is the standard of care for many types of mali
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Khan, Mahir, Ryan Huu-Tuan Nguyen, Mary Pasquinelli, and Lawrence Eric Feldman. "Molecular testing in advanced lung adenocarcinoma: A single-center experience." Journal of Clinical Oncology 39, no. 15_suppl (2021): e21157-e21157. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e21157.

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e21157 Background: Standard of care testing prior to first-line therapy for advanced lung non-small cell lung cancer (NSCLC) includes EGFR mutations, ALK rearrangements, and PD-L1 expression. There is limited real-world evidence on NSCLC molecular testing patterns in underrepresented racial and ethnic populations. Methods: We identified adult patients newly diagnosed with stage IV lung adenocarcinoma at the University of Illinois Hospital & Health Sciences System between January 1, 2015 and October 1, 2019. Rates of biomarker testing for EGFR, ALK, and PD-L1 were determined, as well as the
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Woodman, Scott E., Alexander J. Lazar, Kenneth D. Aldape, and Michael A. Davies. "New Strategies in Melanoma: Molecular Testing in Advanced Disease." Clinical Cancer Research 18, no. 5 (2012): 1195–200. http://dx.doi.org/10.1158/1078-0432.ccr-11-2317.

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Makarem, Maisam, Miguel García-Pardo, and Natasha B. Leighl. "Plasma-Based Genotyping in Advanced Solid Tumors: A Comprehensive Review." Cancers 13, no. 21 (2021): 5299. http://dx.doi.org/10.3390/cancers13215299.

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Molecular genotyping for advanced solid malignancies has transformed the clinical management of patients with metastatic disease. Treatment decisions in a growing number of tumors require knowledge of molecularly driven alterations in order to select optimal targeted therapy. Although genomic testing of tumor tissue is the gold standard for identifying targetable genomic alterations, biopsy samples are often limited or difficult to access. This has paved the way for the development of plasma-based approaches for genomic profiling. Recent advances in the detection of plasma-circulating tumor DN
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Lim, C., H. S. Sekhon, J. C. Cutz, et al. "Improving molecular testing and personalized medicine in non-small-cell lung cancer in Ontario." Current Oncology 24, no. 2 (2017): 103. http://dx.doi.org/10.3747/co.24.3495.

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Background Although molecular testing has become standard in managing advanced nonsquamous non-small-cell lung cancer (nsclc), most patients undergo minimally invasive procedures, and the diagnostic tumour specimens available for testing are usually limited. A knowledge translation initiative to educate diagnostic specialists about sampling techniques and laboratory processes was undertaken to improve the uptake and application of molecular testing in advanced lung cancer.Methods A multidisciplinary panel of physician experts including pathologists, respirologists, interventional thoracic radi
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Carpenter, Rob E. "Beyond Standard Urine Culture: Advanced Molecular Testing for Urinary Tract Infections." SAR Journal of Medicine 5, no. 03 (2024): 80–86. http://dx.doi.org/10.36346/sarjm.2024.v05i03.003.

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In this review article, it is emphasized that adopting advanced molecular diagnostics is essential for modern UTI management, offering a more comprehensive, accurate, and rapid approach compared to traditional methods. Standard urine culture’s limitations include low sensitivity and failure to culture certain microorganisms, leading to undiagnosed cases and increased morbidity. Advanced molecular techniques, like multiplex-PCR and pooled antibiotic susceptibility testing have been shown to reduce empiric treatments and negative outcomes significantly. And advanced molecular methods like metage
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Horbinski, Craig, Keith L. Ligon, Priscilla Brastianos, et al. "The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients." Neuro-Oncology 21, no. 12 (2019): 1498–508. http://dx.doi.org/10.1093/neuonc/noz119.

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Abstract Accurate pathologic diagnoses and molecularly informed treatment decisions for a wide variety of cancers depend on robust clinical molecular testing that uses genomic, epigenomic, and transcriptomic-based tools. Nowhere is this more essential than in the workup of brain tumors, as emphasized by the incorporation of molecular criteria into the 2016 World Health Organization classification of central nervous system tumors and the updated official guidelines of the National Comprehensive Cancer Network. Despite the medical necessity of molecular testing in brain tumors, access to and uti
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Liontos, Michael, Elena Kunadis, Anna Svarna, et al. "Molecular testing for prostate cancer in Greek patients." Journal of Clinical Oncology 40, no. 6_suppl (2022): 170. http://dx.doi.org/10.1200/jco.2022.40.6_suppl.170.

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170 Background: Molecular testing for mutations in genes related to homologous recombination repair (HRR) and microsatellite instability (MSI) is suggested for patients with advanced prostate cancer by international guidelines. Recently, olaparib has been approved for patients with metastatic castration resistant prostate cancer patients that bear mutations in BRCA1/2 genes in Europe. In Greece, molecular testing for prostate cancer patients is not reimbursed. In this setting we describe our experience from investigating the molecular profile of patients with advanced/metastatic disease. Metho
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Teh, Jiasian, Ellen O'Connor, Jonathon O'Brien, et al. "Future directions in advanced penile cancer – mechanisms of carcinogenesis and a search for targeted therapy." Future Oncology 16, no. 29 (2020): 2357–69. http://dx.doi.org/10.2217/fon-2020-0434.

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Penile squamous cell carcinoma (SCC) is a rare and aggressive urological malignancy. Advanced penile SCC requires multimodal management, including surgery and systemic therapy. Given its rarity, there have been few substantial advances in our understanding of the molecular and genomic drivers of penile SCC, especially for patients with relapsed or advanced disease. In this review, we discuss the molecular and genomic landscape of penile SCC, clinical trials in progress and implications for novel therapeutic targets. Future work should focus on preclinical models to provide a platform for inves
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Dissertations / Theses on the topic "Advanced molecular testing"

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Price, David Wilson Jr. "Advances in molecular electronics: Synthesis and testing of potential molecular electronic devices." Thesis, 2003. http://hdl.handle.net/1911/18598.

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New potential molecular electronics devices have been synthesized based on our knowledge of previous systems that have come out of our group. Previous studies and current studies have shown that simple molecular systems demonstrate negative differential resistance (NDR) and memory characteristics. The new systems rely primarily on the redox properties of the compounds to improve upon the solid state properties already observed. Most of these new organic compounds use thiol-based "alligator clips" for attachment to metal surfaces. Some of the compounds, however, contain different "alligator cli
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Rawlett, Adam Madison. "Advances in molecular scale electronics: Synthesis and testing of nanoscale wires and devices." Thesis, 2000. http://hdl.handle.net/1911/19551.

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Chapter 1 discusses advances in molecular scale electronics. With the miniaturization of transistors on silicon semiconductor chips comes faster processing speeds and more powerful computational power; however, certain size constraints on today's semiconductor industry will soon be realized. Therefore, a new method of computer architecture must be developed. The use of a discrete, highly conjugated organic molecule as a molecular scale wire to conduct an electric current has been demonstrated. We have developed molecular scale gates, from organic molecules, that can be altered "on" and "off" w
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Books on the topic "Advanced molecular testing"

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Advanced Microfluidics Based Point-Of-care Diagnostics. Taylor & Francis Group, 2022.

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McKinlay Gardner, R. J., and David J. Amor. Prenatal Testing Procedures. Edited by R. J. McKinlay Gardner and David J. Amor. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199329007.003.0020.

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This chapter is somewhat technical; it reviews the laboratory methodologies by which a prenatal diagnosis can be made and the clinical procedures whereby tissue is obtained. The main indications for prenatal cytogenetic diagnosis are the pregnant woman being of older childbearing age, parental heterozygosity for a chromosome rearrangement, the birth of a previous child with a chromosome defect, increased risk on maternal screening tests, and fetal anomaly detected on ultrasonography. The move to molecular methodology is noted. The remarkable advances in NIPT (noninvasive prenatal testing), suc
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LaGrave, Danielle, Patricia L. Devers Winters, and Geralyn Lambert-Messerlian. Prenatal Screening Technologies and Test Issues. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190604929.003.0007.

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Maternal serum screening began with the measurement of serum alpha fetal protein to detect open neural tube defects, which led to the implementation of routine serum-based prenatal screening in the second trimester for Down syndrome. Advances via combined and integrated screening allowed for the first-trimester detection of both Down syndrome and trisomy 18. Next-generation sequencing has enabled the identification of aneuploidies in circulating cell-free fetal DNA from the plasma fraction of maternal whole blood. This breakthrough in molecular genetic testing, commonly referred to as noninvas
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Casanova, Nancy G., Ting Wang, Eddie T. Chiang, and Joe G. N. Garcia. Genomics, Epigenetics, and Precision Medicine in Integrative Preventive Medicine. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190241254.003.0004.

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This chapter briefly reviews the use of genomewide screening for early detection, treatment, and prevention and the utility of genome-based biomarkers as a tool for precision medicine and its application to population and integrative preventive medicine. Advances in technology have made genomic screening more affordable and widely available, and both our understanding and the value of testing grow as more data is collected. Even more recently, the growing availability of epigenetic testing, methylation and ROS-associated molecular signatures are providing more insight into dynamic aspects of t
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Surveillance of Bacterial Pneumonia and Meningitis in Children Aged Under 5 Years: Field Guide. Second Edition. Pan American Health Organization, 2021. http://dx.doi.org/10.37774/9789275121894.

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The field guide on Surveillance of Bacterial Pneumonia and Meningitis in Children Aged Under 5 Years has become an important reference manual for health professionals in the Region of the Americas involved in epidemiological surveillance. It provides information on diseases, principal etiologic agents, available vaccines, laboratory procedures, and surveillance activities to detect and monitor cases, as well as data analysis to generate relevant information. This second edition describes some new developments as well as updating procedures to reflect advances in molecular testing for laborator
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Nestler, Eric J. The Biological Basis of Depression. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190603342.003.0001.

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Most major advances in biomedical research have relied on the use of animal and cell models of disease. This is a particularly difficult challenge in psychiatry, because many core symptoms of mental illnesses are inherently inaccessible in animals. Moreover, because still today there are no bona fide molecular-cellular abnormalities that are pathogenomic for these illnesses, cell models are even more far afield. This chapter reviews efforts to overcome these obstacles and use animal and cell studies to better understand the biological basis of depression and to develop improved treatments. An
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Camilleri, Michael. Mayo Clinic Illustrated Textbook of Neurogastroenterology. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780197512104.001.0001.

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Mayo Clinic Illustrated Textbook of Neurogastroenterology reflects experience covering the spectrum and maturation of the field of gastrointestinal motility— from studies of exotic patterns of myoelectric recordings in research laboratories to a clinical discipline with major advances in the clinical management of thousands of patients seen by gastroenterologists, primary care physicians, surgeons, or neurologists. Development of the specialty has been characterized by advances in imaging, developments of methods to measure diverse motor and sensory functions from the stomach to the anorectum,
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Winter, Christian, and Peter Albers. Testicular cancer. Edited by James W. F. Catto. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0090.

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Testicular germ cell tumours (GCTs) represent the most common solid malignancy of young men aged 15–40 years. The disease is rising in incidence. Germ cell tumours are best divided into those with pure seminoma and non-seminoma (NSGCT) histology. While cryptorchidism is clearly established as a risk factor, the pathogenesis of testicular cancer remains unknown. Familial studies and molecular analyses suggest an association to genetic alterations. Most testicular cancer patients present a primary tumour in the testis. Diagnostic examinations include testis palpation and ultrasound, and measurem
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Mody, Rajal K., Angela Ahlquist Cleveland, Shawn R. Lockhart, and Mary E. Brandt. Epidemiology of fungal disease. Edited by Christopher C. Kibbler, Richard Barton, Neil A. R. Gow, Susan Howell, Donna M. MacCallum, and Rohini J. Manuel. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755388.003.0007.

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Surveillance and outbreak investigations are important epidemiological tools for assessing the frequency, distribution, and determinants of infections. The primary goal of these activities is to identify measures to reduce the burden of disease. This chapter describes examples of surveillance and approaches to outbreak investigations that have formed the basis of fungal infection control measures. However, considerable knowledge gaps exist, new threats are emerging (including antifungal resistance), and healthcare advances are making more people susceptible to severe fungal infections. Expande
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Weil, Andrew. Integrative Environmental Medicine. Edited by Aly Cohen and Frederick S. vom Saal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190490911.001.0001.

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Integrative Environmental Medicine looks at the history and changing landscape of environmental issues in the United States, including water supply, air quality, extensive plastic pollution, harmful chemicals in cleaning and personal care products, radiofrequency radiation, food additives, pesticides, and medications. The unique properties of compounds such as endocrine-disrupting chemicals are explored along with their ability to disturb the body’s normal signaling pathways, genetic profile, and gut microbiome. Resulting molecular derangements promote thyroid and other autoimmune diseases, di
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Book chapters on the topic "Advanced molecular testing"

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Lin, Patrick S., and Thomas J. Semrad. "Molecular Testing for the Treatment of Advanced Colorectal Cancer: An Overview." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7765-9_18.

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Sanz-Garcia, Enrique, and Lillian L. Siu. "Targeting Molecular Residual Disease Using Novel Technologies and Clinical Trials Design in Head and Neck Squamous Cell Cancer." In Critical Issues in Head and Neck Oncology. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-23175-9_18.

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AbstractHigh-risk human papillomavirus (HPV)-related and most cases of HPV-negative locoregionally advanced head and neck squamous cell carcinoma (LA-HNSCC) have substantial risks of relapse despite definitive therapy, and thus represent conditions of unmet clinical need. The ability now exists to detect molecular residual disease (MRD) in these patients post-definitive treatment such as surgery or (chemo)radiotherapy using novel and highly sensitive and specific technologies to measure cancer-derived circulating biomarkers. The positive and negative predictive values of these assays to foreca
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Nkeze, Joseph Ntumbong, Niel T. Constantine, and Richard Y. Zhao. "Laboratory Testing for HIV Infection: Advances After 28 Years." In Molecular Diagnostics. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8127-0_6.

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Sundareswaran, S., P. Ray Choudhury, C. Vanitha, and Devendra K. Yadava. "Seed Quality: Variety Development to Planting—An Overview." In Seed Science and Technology. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-5888-5_1.

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AbstractThe importance of availability of quality seed of high-yielding varieties in achieving food security has been recognized globally. The chapter presents an overview of the activities and requirements of seed production system globally, with an emphasis on quality, and highlights the linkages between variety development and seed production programmes. The seed development in angiosperm through the process of fertilization has been briefly touched and understanding the processes underlying pollination, fertilization, seed development, and maturation, which are vital for production of qual
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Simundic, A. M., V. Basic, E. Topic, et al. "Soluble Adhesion Molecules In Acute Stroke." In Advances in Critical Care Testing. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18480-2_11.

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Cirillo, Daniela M., Paolo Miotto, and Enrico Tortoli. "Evolution of Phenotypic and Molecular Drug Susceptibility Testing." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-64371-7_12.

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Markovič, S., H. Daxecker, Ì. Raab, A. Griesmacher, and M. M. Müller. "Adhesion Molecules In An In Vitro Model Of Graft Rejection." In Advances in Critical Care Testing. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18480-2_24.

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Porvaznik, I., J. Mokry, and I. Solovic. "Classical Against Molecular-Genetic Methods for Susceptibility Testing of Antituberculotics." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2014. http://dx.doi.org/10.1007/5584_2014_28.

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Carrier, Benoit, Matthieu Vandamme, Roland Pellenq, and Henri Van Damme. "Measurement of Mechanical Properties of Thin Clay Films and Comparison with Molecular Simulations." In Advances in Laboratory Testing and Modelling of Soils and Shales (ATMSS). Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-52773-4_8.

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Kaminsky, E. B., and C. L. Martin. "Technological Advances in the Molecular Cytogenetic Diagnosis of Mental Retardation: Telomere Testing and Genome-wide Array Analysis." In Genetics of Mental Retardation. KARGER, 2010. http://dx.doi.org/10.1159/000287594.

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Conference papers on the topic "Advanced molecular testing"

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Smyk, E. B., J. E. Hoots, K. P. Fivizzani, and K. E. Fulks. "The Design and Application of Polymers in Cooling Water Programs." In CORROSION 1988. NACE International, 1988. https://doi.org/10.5006/c1988-88014.

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Abstract Polymer technology for cooling water applications has advanced significantly in recent years. A variety of monomers and functional groups can be incorporated into a single polymer capable of handling a variety of problems. The development of cooling water polymers is traced through the design stage, screening and optimization, and final application testing. This process illustrates how structure can be modified to optimize performance. By choosing the best monomers and optimizing composition and molecular weight, new polymers with superior performance can be developed. These advanceme
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Robbins, Winston, Sridhar Srinivasan, and Gerrit Buchheim. "Predicting Hot Oil Corrosion: a Framework for Quantifying Reactive Organic Sulfur Compounds in Crude Unit Process Streams." In CONFERENCE 2023. AMPP, 2023. https://doi.org/10.5006/c2023-19105.

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Abstract Sulfur has long been recognized to contribute to many forms of corrosion in petroleum refining. One of the most common and least understood forms of corrosion is hot oil sulfidation, i.e., localized wall thinning by reactive organic sulfur compounds (ROSC) in CDU and VDU operations. In oil at 400-750F (204-400C), Simultaneous Naphthenic Acid alongside Sulfidation (SNAPS) reactions remove iron (Fe) from steel surfaces. Discrepancies in observed corrosion among refinery operators (through inspection) and laboratory testing are frequently due to differences in sulfur analyses of oils. In
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Prasad, Rupi. "Assessment and Control of MIC in the Oil Industry in the 20Th Century." In CORROSION 2000. NACE International, 2000. https://doi.org/10.5006/c2000-00390.

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Abstract At the turn of the 20th century Microbiologically Influenced Corrosion (MIC) in the oil industry was recognized simply as a problem. By the end of the century MIC became a multidisciplinary field of science, incorporating microbiology, molecular biology, electrochemistry, metallurgy, biophysics and biochemistry. Advances in MIC testing techniques utilizing sophisticated tools have contributed significantly to the understanding of the mechanisms involved and control of MIC in the industry. The progress in the assessment and control of MIC in the oil industry during the 20th century is
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Rizavi, Dawar, Thushara Bandara, and Jaymin Morjaria. "Is EBUS sampling adequate for molecular testing in patients with advanced NSCLC?" In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.3466.

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Zhang, Z. G., F. Z. Fang, and C. K. Sun. "Nanoscale cutting mechanism by molecular dynamics simulation." In 3rd International Symposium on Advanced Optical Manufacturing and Testing Technologies: Design, Manufacturing, and Testing of Micro- and Nano-Optical Devices and Systems, edited by Sen Han, Tingwen Xing, Yanqiu Li, and Zheng Cui. SPIE, 2007. http://dx.doi.org/10.1117/12.782508.

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Wang, Weiqiang, Lu Chen, Renjie Gu, et al. "Molecular beam epitaxy of HgCdTe on (211)B CdZnTe." In 6th International Symposium on Advanced Optical Manufacturing and Testing Technologies (AOMATT 2012), edited by Yadong Jiang, Junsheng Yu, and Zhifeng Wang. SPIE, 2012. http://dx.doi.org/10.1117/12.977856.

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Qian, Jincheng, Junsheng Yu, Shuangling Lou, Yadong Jiang, and Qing Zhang. "Influence of hole transporter doping on electroluminescent property of novel fluorene molecular material." In 4th International Symposium on Advanced Optical Manufacturing and Testing Technologies: Advanced Optical Manufacturing Technologies, edited by Li Yang, John M. Schoen, Yoshiharu Namba, and Shengyi Li. SPIE, 2009. http://dx.doi.org/10.1117/12.831036.

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Li, Lu, Wei Li, Junsheng Yu, et al. "Bright-yellow molecular organic light-emitting diodes based on two novel silole derivatives." In 3rd International Symposium on Advanced Optical Manufacturing and Testing Technologies: Advanced Optical Manufacturing Technologies, edited by Li Yang, Yaolong Chen, Ernst-Bernhard Kley, and Rongbin Li. SPIE, 2007. http://dx.doi.org/10.1117/12.783639.

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Xu, Zhongfeng, Kairu Ju, and Qing'an Xu. "Study of the optical properties of ZnO thin films prepared by laser molecular beam epitaxy." In 2nd international Symposium on Advanced Optical Manufacturing and Testing Technologies, edited by Li Yang, Shangming Wen, Yaolong Chen, and Ernst-Bernhard Kley. SPIE, 2006. http://dx.doi.org/10.1117/12.674255.

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Zhang, Junjie, Kai Du, Fangda Xu, Tao Sun, and Yongjian Tang. "Effect of chain length on nanoscratching of polystyrene: a molecular dynamics study." In 6th International Symposium on Advanced Optical Manufacturing and Testing Technologies (AOMATT 2012), edited by Tianchun Ye, Song Hu, Yanqiu Li, Xiangang Luo, and Xiaoyi Bao. SPIE, 2012. http://dx.doi.org/10.1117/12.971202.

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Reports on the topic "Advanced molecular testing"

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Hawkins, Brian T., and Sonia Grego. A Better, Faster Road From Biological Data to Human Health: A Systems Biology Approach for Engineered Cell Cultures. RTI Press, 2017. http://dx.doi.org/10.3768/rtipress.2017.rb.0015.1706.

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Traditionally, the interactions of drugs and toxicants with human tissue have been investigated in a reductionist way—for example, by focusing on specific molecular targets and using single-cell-type cultures before testing compounds in whole organisms. More recently, “systems biology” approaches attempt to enhance the predictive value of in vitro biological data by adopting a comprehensive description of biological systems and using computational tools that are sophisticated enough to handle the complexity of these systems. However, the utility of computational models resulting from these eff
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Lehotay, Steven J., and Aviv Amirav. Fast, practical, and effective approach for the analysis of hazardous chemicals in the food supply. United States Department of Agriculture, 2007. http://dx.doi.org/10.32747/2007.7695587.bard.

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Background to the topic: For food safety and security reasons, hundreds of pesticides, veterinary drugs, and environmental pollutants should be monitored in the food supply, but current methods are too time-consuming, laborious, and expensive. As a result, only a tiny fraction of the food is tested for a limited number of contaminants. Original proposal objectives: Our main original goal was to develop fast, practical, and effective new approaches for the analysis of hazardous chemicals in the food supply. We proposed to extend the QuEChERS approach to more pesticides, veterinary drugs and pol
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Chefetz, Benny, Baoshan Xing, Leor Eshed-Williams, Tamara Polubesova, and Jason Unrine. DOM affected behavior of manufactured nanoparticles in soil-plant system. United States Department of Agriculture, 2016. http://dx.doi.org/10.32747/2016.7604286.bard.

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The overall goal of this project was to elucidate the role of dissolved organic matter (DOM) in soil retention, bioavailability and plant uptake of silver and cerium oxide NPs. The environmental risks of manufactured nanoparticles (NPs) are attracting increasing attention from both industrial and scientific communities. These NPs have shown to be taken-up, translocated and bio- accumulated in plant edible parts. However, very little is known about the behavior of NPs in soil-plant system as affected by dissolved organic matter (DOM). Thus DOM effect on NPs behavior is critical to assessing the
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