Relevant bibliographies by topics / Clinical and immunological changes

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Clinical and immunological changes'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Clinical and immunological changes"

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Schwab, Nicholas, Karin G. Höhn, Tilman Schneider-Hohendorf, et al. "Immunological and clinical consequences of treating a patient with natalizumab." Multiple Sclerosis Journal 18, no. 3 (2011): 335–44. http://dx.doi.org/10.1177/1352458511421919.

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Background: Long-term therapy with natalizumab increases the risk of progressive multifocal leukoencephalopathy (PML). Objectives: We present a patient study through therapy, the diagnosis of PML (after 29 infusions), plasma exchange (PE) and development of immune reconstitution inflammatory syndrome (IRIS). Methods: Routine diagnostics, magnetic resonance imaging (MRI), immunological status (flow cytometry, T-cell migration assays and T-cell repertoire analysis), and brain biopsy with immunohistological analysis. Results: CD49d decreased after 12 months of treatment. At PML diagnosis, CD49d e
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Maruf, Gadoev, and Bakhromuddin Saidzoda. "CLINICAL AND IMMUNOLOGICAL CHANGES OF NON-GONOCOCCAL URETHRITIS." Avicenna Bulletin 22, no. 1 (2020): 40–44. http://dx.doi.org/10.25005/2074-0581-2020-22-1-40-44.

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Objective: To study the clinical features and the state of general immunological reactivity in non-gonococcal urethritis (NGU) in men. Methods: Examined 100 men between the ages of 20 and 48 years: 75 patients of NGU (main group) and 25 healthy (control group). The average age of the patients was 26.7±1.7 years, and the male of control group was 27.9±1.7 years. Clinical, microscopic, immunological research methods were used, including direct immunofluorescence (DIF), polymerase chain reaction (PCR). Results: Ureaplasma urealyticum was found in 37 (49.3%) patients, 33 (44%) had Chlamydia tracho
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Tamási, Lilla, Ildikó Horváth, Anikó Bohács, Veronika Müller, György Losonczy, and Michael Schatz. "Asthma in pregnancy – Immunological changes and clinical management." Respiratory Medicine 105, no. 2 (2011): 159–64. http://dx.doi.org/10.1016/j.rmed.2010.11.006.

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HILL, D. J., C. S. HOSKING, M. J. SHELTON, and M. W. TURNER. "Childhood asthma: clinical and immunological changes over a decade." Clinical Experimental Allergy 21, no. 3 (1991): 343–49. http://dx.doi.org/10.1111/j.1365-2222.1991.tb01666.x.

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Tylutka, Anna, and Agnieszka Zembroń-Łacny. "Immunological aging and clinical consequences." Postępy Higieny i Medycyny Doświadczalnej 74 (July 8, 2020): 260–71. http://dx.doi.org/10.5604/01.3001.0014.3054.

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Immunosenescence is defined as the changes in the immune system associated with age. It is a progressive and irreversible process involving a decrease in the number of naïve T and B cells, NK cells cytotoxic and activity, and disruption of pro and anti-inflammatory balance by altering the production of IL-2, -4, -6, -10, -10, TNF-α, interferon γ and others. With age there is an increase in autoimmunity and generalized inflammation with simultaneous immunodeficiency, which results in greater susceptibility to infectious diseases, a decrease in reactivity to prophylactic vaccinations, the incide
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Zhou, Julie Y., and Brian A. Cobb. "Glycans in Immunologic Health and Disease." Annual Review of Immunology 39, no. 1 (2021): 511–36. http://dx.doi.org/10.1146/annurev-immunol-101819-074237.

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The surfaces of all living organisms and most secreted proteins share a common feature: They are glycosylated. As the outermost-facing molecules, glycans participate in nearly all immunological processes, including driving host-pathogen interactions, immunological recognition and activation, and differentiation between self and nonself through a complex array of pathways and mechanisms. These fundamental immunologic roles are further cast into sharp relief in inflammatory, autoimmune, and cancer disease states in which immune regulation goes awry. Here, we review the broad impact of glycans on
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Baars, Erik W., Miek Jong, Andreas F. M. Nierop, Inge Boers, and Huub F. J. Savelkoul. "Citrus/Cydonia Compositum Subcutaneous Injections versus Nasal Spray for Seasonal Allergic Rhinitis: A Randomized Controlled Trial on Efficacy and Safety." ISRN Allergy 2011 (July 18, 2011): 1–11. http://dx.doi.org/10.5402/2011/836051.

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Background. Clinical experiences in vitro and clinical studies have demonstrated the curative potency and safety of Citrus/Cydonia compositum in seasonal allergic rhinitis treatment. Objectives. To compare the efficacy and safety of two routes of administration (nasal spray versus subcutaneous injections). Methodology: Design. a national, randomised, comparative clinical trial with two parallel groups. Participants. 23 patients fulfilled the study requirements. Intervention. after a one- or two-week wash-out period, 23 patients were randomized, to a 6-week treatment period. Outcomes. immunolog
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Taylor, J., R. Afrasiabi, JL Fahey, E. Korns, M. Weaver, and R. Mitsuysau. "Prognostically significant classification of immune changes in AIDS with Kaposi's sarcoma." Blood 67, no. 3 (1986): 666–71. http://dx.doi.org/10.1182/blood.v67.3.666.666.

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Abstract Sixteen immunological parameters were assessed quantitatively for their value in providing an immunologically-based and prognostically significant classification of the immune alteration in 97 patients with AIDS and Kaposi's sarcoma (AIDS-KS). The dimensions of reductions in the T4 (T helper-inducer cells) subpopulation of lymphoid cells in the T4-T8 ratio were found to correlate most closely with prognosis. Most other immunological changes did not relate to clinical course. T4 lymphocyte levels greater than 300/microL and a T4-T8 ratio greater than 0.5 indicated a relatively good pro
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Taylor, J., R. Afrasiabi, JL Fahey, E. Korns, M. Weaver, and R. Mitsuysau. "Prognostically significant classification of immune changes in AIDS with Kaposi's sarcoma." Blood 67, no. 3 (1986): 666–71. http://dx.doi.org/10.1182/blood.v67.3.666.bloodjournal673666.

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Sixteen immunological parameters were assessed quantitatively for their value in providing an immunologically-based and prognostically significant classification of the immune alteration in 97 patients with AIDS and Kaposi's sarcoma (AIDS-KS). The dimensions of reductions in the T4 (T helper-inducer cells) subpopulation of lymphoid cells in the T4-T8 ratio were found to correlate most closely with prognosis. Most other immunological changes did not relate to clinical course. T4 lymphocyte levels greater than 300/microL and a T4-T8 ratio greater than 0.5 indicated a relatively good prognosis, e
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Axmedovich, Makhmudov Farxod, Sharopova Gulnoza Samadovna, and Sultonov Sohib Obidovich. "Observation of immunological changes during clinical cycles of skin leishmaniosis." ACADEMICIA: An International Multidisciplinary Research Journal 11, no. 5 (2021): 618–22. http://dx.doi.org/10.5958/2249-7137.2021.01449.x.

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Dissertations / Theses on the topic "Clinical and immunological changes"

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Gibson, John. "Orofacial granulomatosis : clinical and immunological studies." Thesis, University of Glasgow, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266680.

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Huang, Dennis Shihchang. "Immunological changes in retrovirus-infected mice." Diss., The University of Arizona, 1993. http://hdl.handle.net/10150/186463.

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Acquired Immune Deficiency Syndrome (AIDS), a progressive immunodeficiency induced by Human Immunodeficiency Virus (HIV), frequently sets the stage for life-threatening tumors and opportunistic infections. The proposed study focuses on the immunological changes associated with HIV infection. Often superimposed diarrhea, causing malabsorption and malnutrition, leads to further immunosuppression and accelerated deterioration in many patients. The pathomechanism of Cryptosporidium-induced diarrhea is poorly understood and its relation to AIDS urgently requires investigation. We used LP-BM5 murine
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Sjöwall, Johanna. "Clinical and Immunological Aspects of Lyme borreliosis." Doctoral thesis, Linköpings universitet, Infektionsmedicin, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-68745.

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Lyme borreliosis (LB) is a tick-borne infection caused by spirochetes of the Borrelia (B.) burgdorferi sensu lato complex. The infection is associated with several clinical features, of which erythema migrans (EM) and neuroborreliosis (NB) are the most common in Europe. The prognosis after antibiotic therapy is generally good. However, some patients may have residual symptoms post-treatment. The cause of the delayed convalescence is unclear. There are several factors that may affect the clinical outcome of LB, for example, the early interaction between the host’s immune response and B. burgdor
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Fennerty, A. G. "Clinical and immunological studies in hay fever." Thesis, University of Liverpool, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382062.

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Hourihane, Jonathan O'Brien. "Clinical & immunological features of peanut allergy." Thesis, University of Southampton, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242421.

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Kitley, Joanna Louise. "A clinical/immunological neuromyelitis optica association study." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:274bb81c-edce-4f6f-8330-172659ba99fc.

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Neuromyelitis optica (NMO) and NMO spectrum disorders (NMOSD) are associated with the disease-specific autoantibody aquaporin-4 (AQP4-Ab), which is thought to be pathogenic. Some NMO/NMOSD patients do not have this antibody and may have different clinical and immuno-pathological disease characteristics, but previous clinical NMO/NMOSD studies have been confounded by inclusion of such patients. To define better the characteristics of AQP4-Ab disease, disease course, outcomes and predictors of disability were investigated in 106 AQP4-Ab positive NMO/NMOSD patients from the UK and Japan. AQP4-Ab
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Bernstrand, Cecilia. "Langerhans cell histiocytosis : a clinical and immunological study /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-468-2/.

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Hedin, Skogman Barbro. "Neuroborreliosis in childhood : Clinical, immunological and diagnostic aspects." Doctoral thesis, Linköpings universitet, Pediatrik, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-11520.

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Lyme Borreliosisis is a multi-organ infectious disease caused by the spirochete Borrelia burgdorferi. The spirochete is transmitted to humans by tick bites. Neuroborreliosis (NB) is a disseminated form of the disease, in which the spirochetes invade the nervous system. In children, subacute meningitis and facial nerve palsy are typical clinical manifestations of NB. The aim of this thesis was to study clinical, immunological and laboratory characteristics in children being evaluated for NB in a Lyme endemic area of Sweden, in order to identify factors of importance for prognosis and clinical r
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Robertson, William Duncan. "Oral keratoses : a clinical, pathological and immunological study." Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/20152.

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The diagnosis of a patient presenting with an oral keratosis is the first stage in the management of the patient. Diagnosis is based on a combination of patient history, clinical examination and laboratory investigations. The aim of this thesis was to identify factors which may be helpful in the diagnosis of oral keratoses. It is based on a prospective study of 159 patients being examined haematologially, immunologically and histopathologically. Two main groups of keratoses were identified by the presence or absence of an associated inflammatory cell infiltrate. Infiltrated keratoses comprised
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Söderlund, Stina. "Clinical and Immunological Studies in Chronic Myeloid Leukaemia." Doctoral thesis, Uppsala universitet, Hematologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-324272.

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Chronic myeloid leukaemia (CML) is characterised by the constitutively active tyrosine kinase BCR-ABL. Standard treatment with tyrosine kinase inhibitors (TKI) in the chronic phase (CP) of CML conveys excellent long-term prognosis but is associated with side effects and costs. Treatment free remission (TFR) is possible in a proportion of patients discontinuing treatment after obtaining deep treatment responses but it is not fully known how to select the right patients for stopping attempts. Treatment of accelerated phase (AP) and blast crisis (BC) is more complicated and the prognosis more dis
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Books on the topic "Clinical and immunological changes"

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Zemskov, Vladimir, Veronika Zemskova, Andrey Mironov, and Sergey Suchkov. Clinical immunology and allergology. INFRA-M Academic Publishing LLC., 2023. http://dx.doi.org/10.12737/1048793.

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The textbook "Clinical Immunology and Allergology" covers modern data on the phenomena, mechanisms of development, physiological changes in immunological reactivity, metabolic immunity, as well as on the diagnosis, prevention and treatment of immunodeficiency, allergies, immunosuppressive and immunoassociated non-infectious and infectious diseases. It consists of eight sections, 33 chapters, intermediate and final control tests, an electronic handbook of methods for assessing immune status, infections, immunotropic, antiallergic and other medications.
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H, Lessof Maurice, Lee T. H, and Kemeny D. M, eds. Allergy: Immunological and clinical aspects. 2nd ed. Wiley, 1987.

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Norman, Talal, Moutsopoulos H. M, and Kassan S. S, eds. Sjögren's syndrome: Clinical and immunological aspects. Springer-Verlag, 1987.

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Leslie, Brent, and Sells Robert A, eds. Organ transplantation: Current clinical and immunological concepts. Baillière Tindall, 1989.

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L, Gross Wolfgang, International Workshop on ANCA, (4th : 1992 : Lübeck, Germany), and International Colloquium on Wegener's Granulomatosis and Vasculitic Disorders, (2nd : 1992 : Lübeck, Germany), eds. ANCA-associated vasculitides: Immunological and clinical aspects. Plenum Press, 1993.

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Leslie, Brent, and Sells Robert A, eds. Organ transplantation: Current clinical and immunological concepts. Bailliere Tindall, 1989.

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1967-, Mastroeni Pietro, and Maskell Duncan 1961-, eds. Salmonella infections: Clinical, immunological, and molecular aspects. Cambridge University Press, 2005.

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George, Kahaly, ed. Endocrine ophthalmopathy: Molecular, immunological and clinical aspects. Karger, 1993.

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Kalm, Olof. Recurrent acute otitis media: Immunological and clinical aspects. [s.n.], 1986.

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Brostrom, Hans. Equine sarcoids: A clinical, epidemiological and immunological study. Sveriges Lantbruksuniversitet, 1995.

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Book chapters on the topic "Clinical and immunological changes"

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Fulop, Tamas, Anis Larbi, Abdelouahed Khalil, Katsuiku Hirokawa, Alan A. Cohen, and Jacek M. Witkowski. "Immunological Changes." In The Very Old Critically Ill Patients. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94133-8_6.

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Mu, Hong, Chunlei Zhou, Ling Fang, Feng Xie, Yan Zhang, and Huanhuan Chen. "Immunological Disorders." In Clinical Molecular Diagnostics. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-1037-0_32.

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Lawler, Sylvia D., and Rosemary A. Fisher. "Immunological Aspects." In Clinical Perspectives in Obstetrics and Gynecology. Springer New York, 1987. http://dx.doi.org/10.1007/978-1-4612-4698-5_7.

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Stevens, Vernon C. "Immunological Contraception." In Clinical Perspectives in Obstetrics and Gynecology. Springer New York, 1993. http://dx.doi.org/10.1007/978-1-4612-2730-4_19.

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Pelletier, Lucette, Abdelhadi Saoudi, and Gilbert Fournié. "Toxin-induced immunological renal disease." In Clinical Nephrotoxins. Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-84843-3_7.

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Hendry, W. F. "Immunological Aspects of Male Infertility." In Advances in Clinical Andrology. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-1237-3_6.

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Ackermann, R. "Immunological Aspects of Bladder Cancer." In Clinical Practice in Urology. Springer London, 1985. http://dx.doi.org/10.1007/978-1-4471-1362-1_3.

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Litwin, Christine M. "Immunological Tests in Tuberculosis." In Manual of Molecular and Clinical Laboratory Immunology. ASM Press, 2016. http://dx.doi.org/10.1128/9781555818722.ch48.

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Klimov, Vladimir V. "Immunological and Molecular Biological Methods." In From Basic to Clinical Immunology. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-03323-1_5.

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Galea, G., and S. J. Urbaniak. "Tissue Typing and Immunological Aspects of Organ Transplantation." In Clinical Transplantation. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3217-3_3.

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Conference papers on the topic "Clinical and immunological changes"

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Mim, Umme Marium, Whitney Ann Lowe, Varsha Karunakaran, April Mordi, and Narasimhan Rajaram. "Investigating Tissue Changes Due to Alcohol and Tobacco Consumption Using Optical Spectroscopy." In Clinical and Translational Biophotonics. Optica Publishing Group, 2025. https://doi.org/10.1364/translational.2025.tm3f.4.

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Bueno, Juan M., Marcelino Avilés-Trigueros, and Nazario Bautista-Elivar. "Diabetes-Related Changes in Retinal Tissues Imaged with Two-photon Microscopy: Structural and Neuroinflammation Effects." In Clinical and Translational Biophotonics. Optica Publishing Group, 2025. https://doi.org/10.1364/translational.2025.tth1e.5.

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Two-photon imaging microscopy has been used to explore the changes suffered by the retinal photoreceptors of a diabetic retinopathy rat model. Images reveal different cellular organization and noticeable neuroinflammation effects when comparing control and pathological specimens. .
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Sabaghian, Sahar, Chiensing Poon, Timothy M. Rambo, Aaron J. Miller, Brandon Foreman, and Ulas Sunar. "Monitoring of depth-sensitive blood flow changes using time-gated diffuse correlation spectroscopy in NeuroICU." In Clinical and Translational Neurophotonics 2025, edited by Jana M. Kainerstorfer, Erin M. Buckley, and Vivek J. Srinivasan. SPIE, 2025. https://doi.org/10.1117/12.3043486.

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Störkel, F., I. Scharrer, L. Hovy, J. Rüdigier, and S. Störkel. "HAEMOPHILIC ARTHROPATHY: IMMUNOLOGICAL MECHANISMS AND SYNOVITIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644023.

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Up to now questions of pathogenisis in hemophilic arthropathy are still remaining, i.e. humoral mediated imnunological mechanisms (type II/III reactions) are supposed to play an important role (Arnold and Hilgartner (1977), Rippjey (1978)). Therefore we investigated synovial tissue by imnunohistologic technique using antibodies against IgG, IgA, IgM, C1q, C3, fibrinogen ando61-ACT. First we examined synovial membrane biopsies (n=7; non-haemo-philic) following acute traumatic joint bleeding, to study the first and acute bleeding/absorption pahase. Light microscopy showed typical changes as desc
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Cheremisina, O. V., E. L. Choinzonov, V. A. Evtushenko, Anatoly N. Soldatov, O. V. Pankova, and L. V. Gerdt. "A comparative evaluation of efficiency of different methods of treating pretumoral changes of bronchial epithelium by clinical-immunological data." In SPIE Proceedings, edited by Victor F. Tarasenko. SPIE, 2004. http://dx.doi.org/10.1117/12.562989.

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Koller, U., I. Pabinger, K. Lechner, and W. Knapp. "HEAT INACTIVATED HIGHLY PURIFIED FACTOR VIII CONCENTRATE IN THE TREATMENT OF HEMOPHILIACS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644057.

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51 severe hemophiliacs who had previously been treated with not virus-inactivated intermediate purity factor VIII concentrates were divided into two groups according to their immunological status. Group A (n=23) consisted of patients with CD4/CD8 (helper/suppressor) T cell ratio of 1.0, group B (n=28) of . patients with a ratio of 1.0. In patients of group A treatment was switched in May 1983 to highly purified heat inactivated factor VIII concentrate (BEHRINGWERKE GmbH, Marburg) whereas patients of group B continued to receive intermediate purity factor VIII concentrate. In both groups labora
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Amorim, Maria Clara Carvalho Silva de, Karla Oliveira Couto, Pedro José da Silva Júnior, Thiago Gonçalves Fukuda, Pedro Antônio Pereira de Jesus, and Mateus Santana do Rosário. "Hemisferic encephalic involviment associated with sars- cov-2." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.005.

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Context: The novel severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) emerged in Wuhan, China and rapidly spread worldwide. Although the predominant clinical presentation is with respiratory disease, neurological manifestations are being recognised increasingly. Case report: In this report, we demonstrate a case of hemispheric brain in volvement as a neurological manifestation of Sars-cov-2 in a 74-year-old patient admitted to Hospital Santa Izabel (HSI) between May and July 2020. Conclusion: In COVID-19, although the predominant clinical presentation is with respiratory disease, neur
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Campos, M., L. Santos, J. Lobato, C. Melo, and B. Justica. "HTLV III/LAV ANTIBODY STATUS, AND IMMUNOLOGICAL ABNORMALITIES IN A HEMOPHILIC POPULATION FROM PORTUGAL Campos." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644143.

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An immunological study in a population of 46 hemophiliacs (A and B)under replacement therapy mainly with cryo, plasma and eventually withccmercial concentrates was carried out to detect changes related to HTLV III infection and those due totreatment. We followed the patients during 85-87 and we evaluate the abnormalities over a period of 2 years . Methods. Ig's (nephelometry): total lymphocytes, T3, T4, T8 subsets and B cells (IF microcopy):delayed hypersensivity skin tests (DHST) ,7 antigens: serology for HTLV III (ELISA and WB) (β 2 microglobulin (ELISA) Results. In 85,10 patients had anti H
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Arocha Piñango, C. L., A. Torres, R. Marchi, et al. "A NEW THROMBOTIC DYSFIBRINOGENEMIA PRESENT IN SEVERAL MEMBERS OF A VENEZUELAN FAMILY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643340.

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Up to the present, 16 dysfibrinogenemias have been described with thrombotic symptomatology, of which 3 cases showed low affinity of the fibrin for thrombin.In this study, we describe a family with an elevated frequency of thrombotic episodes which may be due to an alteration in the fibrinogen molecule causing a defective adsorption of thrombin by the fibrin formed.Two women, mother and daughter, were admitted to our clinic with a history of repeated pulmonary thromboembolisms. Coagulation studies (which included Antithrombin III, Protein C, etc.) revealed only a prolonged thrombin time with h
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Araldi, Bianca Barbosa, Victor Hugo Gomes, Bruno Ludvig Vieira, et al. "Effects of multiple sclerosis in pregnant and post-birth: particularities of the disease activity." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.704.

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Introduction: Demyelinating diseases are a heterogeneous group of neurological diseases related to autoimmunity whose representative is Multiple Sclerosis (MS). It is characterized by an immune-mediated demyelination of the central nervous system, with a typical outbreak and remission clinic. During pregnancy, a reduction in disease activity was noted due to immunomodulatory effects, and an increase in outbreaks in the puerperium. Thus, our goal is to demonstrate the relationship between pregnancy and MS. Methods: This is a systematic bibliographic review based on searching the SCIELO, PUBMED
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Reports on the topic "Clinical and immunological changes"

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Alarcón, Marco, Tatiana Amagua, Donald Morales, and Ana Lucia Seminario. EFFECT OF PERIODONTAL TREATMENT IN HIV+ PATIENS: A SYSTEMATIC REVIEW. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.1.0032.

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Review question / Objective: The objective of our study is to evaluate whether periodontal treatment influences clinical outcomes and immunological conditions in HIV+ patients. (P) Participants: VIH+ patients. (I) Interventions: Surgical treatment, photodynamic therapy, antimicrobials, others. (C) Comparison: Non-surgical treatment. (O) Outcome measures: - Periodontal outcomes: plaque scores, bleeding on probing, periodontal pocket Depth, clinical attachment levels; - VIH outcomes: -Count CD4+; -Microbiological analysis. Condition being studied: Our study will analyze the effect of periodontal
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Alarcón-Sánchez, Mario Alberto, Giuseppe Minervini, and Artak Heboyan. Clinical and immunological aspects of gingival retraction systems in fixed dental prostheses: A systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.1.0005.

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Thote, Amol, Carolyn Carr, Daniel Vasilchuk, Divya Shastry, Alen Hozanovic, and Rachel Hodges. Demonstrating Comparability for Clinical Cell-based Therapy Products Following Manufacturing Process Changes: An Industry Perspective (Rachael Hodges). BioPhorum, 2023. http://dx.doi.org/10.46220/2023cgt009.

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DiBenedetti, Dana B., T. Michelle Brown, Carla Romano, Claire Ervin, Sandy Lewis, and Sheri Fehnel. Conducting Patient Interviews Within a Clinical Trial Setting. RTI Press, 2018. http://dx.doi.org/10.3768/rtipress.2018.op.0054.1808.

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Qualitative data centered on patients’ experiences and perspectives typically go uncollected in clinical trial settings. Yet patients’ treatment experiences offer complementary insights and context on topics such as disease management, treatment gaps, and previous treatments outside of those gathered in traditional patient-reported outcome questionnaires. Qualitative interviews can capture patients’ perceptions of treatment needs, more fully explore meaningful changes experienced as a result of treatment, and reveal outcomes that are most important to patients. Asking patients detailed questio
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Hu, Quan, Jinsong Jiang, and Qi Li. Changes in medial meniscus extrusion values and clinical outcomes after high tibial osteotomy: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.4.0102.

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Clement, Timothy, and Brett Vaughan. Evaluation of a mobile learning platform for clinical supervision. University of Melbourne, 2021. http://dx.doi.org/10.46580/124369.

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Context: This report details a formative evaluation of the Clinical Supervision Online (CSO) course, a fee-paying, fully online ‘light touch’ program of study for clinical supervisors offered by the Melbourne Medical School, which was developed in conjunction with the University’s Mobile Learning Unit. The course requires between six to ten hours of self-directed study and is designed for any clinicians who teach. Methods: Evaluation of the course was guided by Rossi, Lipsey and Freeman’s (2004) approach to program evaluation, addressing the need for the course, its design, implementation, imp
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Dudley, Lilian D., and Charles Shey Wiysonge. Does giving women their own case notes to carry in pregnancy improve maternal care? SUPPORT, 2016. http://dx.doi.org/10.30846/160804.

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Improvements in antenatal care have included changes to traditional practices in order to improve womens’ experiences of antenatal care and the clinical outcomes of maternity care. One such change has been giving women their own clinical case notes to carry throughout their pregnancy in order to enable women to participate in the decision making regarding their healthcare, and to improve the availability of the records when needed.
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Sokol-Hessner, Lauge, C. Matthew Stewart, Ritu Sharma, et al. Programs for Responding to Harms Experienced by Patients During Clinical Care. Agency for Healthcare Research and Quality (AHRQ), 2025. https://doi.org/10.23970/ahrqepc_mhs4harms.

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Objectives. This rapid review synthesizes the current literature on the effectiveness of programs used by healthcare organizations to respond after patients experience harm during their care. We focused on communication and resolution programs (CRPs) that included communication with the patient and family, event review, quality improvement, and in a qualifying subset of events, an apology for causing harm and an offer of compensation. Methods. We searched PubMed and the Cochrane Library for systematic reviews and primary studies published from January 1, 2010, to July 2024, supplemented by a t
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Barros-Poblete, Marisol, Rodrigo Torres-Castro, Mauricio Henríquez, Anita Guequen, Isabel Blanco, and Carlos Flores. Dysbiosis as a prognostic factor for clinical worsening in chronic respiratory disease: A systematic review and metanalysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0089.

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Review question / Objective: Is dysbiosis a prognostic factor for clinical worsening in patients with chronic respiratory diseases?. Condition being studied: Dysbiosis, defined as changes in the quantitative and qualitative composition of the microbiota. Eligibility criteria: Over 18 years old adult patients with chronic respiratory diseases clinical diagnosis (cystic fibrosis, chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis, interstitial lung disease, sarcoidosis, bronchiectasis, non-CF bronchiectasis, pulmonary hypertension) according to the International Statist
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li, shijue, Wai Leung Ambrose Lo, Minghui Ding, et al. The clinical benefit of interlimb-coordintated intervention in gait recovery and the associated neurophysiological changes in patients with stroke: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.10.0012.

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