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1

Jackevičius, Algirdas, Valerijus Ostapenko, Saulius Bružas, Algimantas Mudėnas, Jonas Sabonis, and Michailas Aizenas. "Nepiktybinių krūties navikų diagnostika ir gydymas." Lietuvos chirurgija 4, no. 2 (2006): 0. http://dx.doi.org/10.15388/lietchirur.2006.2.2273.

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Algirdas Jackevičius, Valerijus Ostapenko, Saulius Bružas, Algimantas Mudėnas, Jonas Sabonis, Michailas AizenasVilniaus universiteto Onkologijos institutas,Santariškių g. 1, LT-08660 VilniusEl paštas: algirdasj@is.lt Tikslas Pateikti sergančiųjų nepiktybiniais krūties navikais klinikinius duomenis. Aprašyti šių darinių diagnostiką ir gydymą. Ligoniai ir metodai Vilniaus universiteto Onkologijos instituto Krūtų ligų ir onkologijos skyriuje nuo 2000 iki 2004 metų gydėsi 1058 ligonės, kurioms buvo diagnozuoti nepiktybiniai krūtų navikai. Dažniausiai (1002 atvejai) ligonėms buvo diagnozuotos fibro
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Loke, Benjamin Nathanael, Nur Diyana Md Nasir, Aye Aye Thike, et al. "Genetics and genomics of breast fibroadenomas." Journal of Clinical Pathology 71, no. 5 (2017): 381–87. http://dx.doi.org/10.1136/jclinpath-2017-204838.

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Fibroadenomas of the breast are benign fibroepithelial tumours most frequently encountered in women of reproductive age, although they may be diagnosed at any age. The fibroadenoma comprises a proliferation of both stromal and epithelial components. The mechanisms underlying fibroadenoma pathogenesis remain incompletely understood. In the clinical setting, distinguishing cellular fibroadenomas from benign phyllodes tumours is a common diagnostic challenge due to subjective histopathological criteria and interobserver differences. Recent sequencing studies have demonstrated the presence of high
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3

Nikumbh, D. B., S. R. Desai, P. S. Madan, N. J. Patil, and J. V. Wader. "Bilateral Giant Juvenile Fibroadenomas of Breasts:A Case Report." Pathology Research International 2011 (May 30, 2011): 1–4. http://dx.doi.org/10.4061/2011/482046.

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Juvenile fibroadenoma constitutes only 4% of the total fibroadenomas. The incidence of giant juvenile fibroadenomas is found to be only 0.5% of all the fibroadenomas. Bilateral giant juvenile fibroadenomas are extremely rare, and only four cases have been reported in the literature. To the best of our knowledge, we are presenting the fifth case of bilateral giant juvenile fibroadenomas in a 12-year-old prepubertal girl. The diagnosis was made on fine-needle aspiration cytology which was confirmed on histopathology. In this paper, we present this rare case to illustrate the diagnosis and manage
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Bairwa, Banwari Lal. "Giant fibroadenoma mimicking phylloides tumor in post-menopausal female: a case report and review of literature." International Surgery Journal 7, no. 12 (2020): 4235. http://dx.doi.org/10.18203/2349-2902.isj20205391.

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Giant fibroadenomas are rare breast lesions in elderly women especially post-menopausal women and accounting for 0.5-2% of all cases of fibroadenomas. They pose diagnostic as well as therapeutic challenge because resemblance of its clinical and imaging features with other breast lesions, especially phylloides tumor. We present a rare case of giant fibroadenoma of breast in postmenopausal female of 53 year of age mimicking phylloides tumor. Ultrasonography and fine needle aspiration cytology (FNAC) suggestive of fibroadenoma. Tumor was completely excised and diagnosis of giant fibroadenoma was
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5

Feliciano, Yara Z., Rochelle Freire, Jose Net, and Monica Yepes. "Ductal and lobular carcinoma in situ arising within an enlarging biopsy proven fibroadenoma." BMJ Case Reports 14, no. 1 (2021): e237017. http://dx.doi.org/10.1136/bcr-2020-237017.

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The diagnosis via core needle biopsy of concurrent ductal carcinoma in situ and lobular carcinoma in situ within an enlarging previously biopsied benign fibroadenoma in women in their 40s is rare. Several case reports have described the occurrence of malignant changes within fibroadenomas, usually as an incidental finding following excision, and few reports have documented the transition of a fibroadenoma to malignancy. The current case report emphasises the importance of re-biopsying enlarging fibroadenomas, even with otherwise maintained benign appearing features on imaging, in women in thei
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Krhovský, Miroslav, Radovan Pilka, Vuk Fait, and Josef Eim. "Giant breast fibroadenoma in pregnancy." Česká gynekologie 86, no. 2 (2021): 114–17. http://dx.doi.org/10.48095/cccg2021114.

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Overview Objective: To present unusual case of rapidly growing breast fibroadenoma during pregnancy. Case report: Breast fibroadenomas are hormone-dependent tumors which can grow rapidly during pregnancy. We present a case of giant fibroadenoma, first detected before pregnancy, which grew rapidly under the influence of pregnancy hormones and was excised in the third trimester. Conclusion: Fibroadenomas are benign breast lesions in young women. They are hormone-dependent tumors, which can grow rapidly especially during pregnancy and/ or lactation and imitate malignancy. In each case of a newly
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7

Bode, M. K., T. Rissanen, and M. Apaja-Sarkkinen. "Ultrasonography and core needle biopsy in the differential diagnosis of fibroadenoma and tumor phyllodes." Acta Radiologica 48, no. 7 (2007): 708–13. http://dx.doi.org/10.1080/02841850701367911.

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Background: The diagnosis of phyllodes tumors of the breast is challenging due to many similarities with common fibroadenomas. Purpose: To determine the diagnostic accuracy of core needle biopsy in diagnosing phyllodes tumors and to analyze the ultrasonographic (US) features of phyllodes tumors and fibroadenomas. Material and Methods: From 1999 to 2003, 1010 breast lesions underwent imaging-guided core needle biopsy. Of these, 57 fibroadenomas and 12 phyllodes tumors were removed surgically. The US and needle biopsy results of a total of 64 lesions (52 fibroadenomas and 12 phyllodes tumors) we
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8

Shin, Sandra J., and Paul Peter Rosen. "Bilateral Presentation of Fibroadenoma With Digital Fibroma–like Inclusions in the Male Breast." Archives of Pathology & Laboratory Medicine 131, no. 7 (2007): 1126–29. http://dx.doi.org/10.5858/2007-131-1126-bpofwd.

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Abstract Fibroepithelial lesions are uncommon in the male breast. Most published reports describe phyllodes tumors. Fibroadenomas are very common in female breasts, but are exceedingly rare in the male breast. Gynecomastia and/or lobular differentiation have been known to coexist in both types of fibroepithelial lesions in men. We report an exceptional case of recurrent, bilateral fibroadenomas in a man under treatment for prostatic carcinoma. Intracytoplasmic inclusion bodies in stromal cells identical to those seen in infantile digital fibromatosis were identified in one fibroadenoma. To the
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9

Maritz, Robert M., and Pamela M. Michelow. "Cytological Criteria to Distinguish Phyllodes Tumour of the Breast from Fibroadenoma." Acta Cytologica 61, no. 6 (2017): 418–24. http://dx.doi.org/10.1159/000477573.

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Objective: To determine whether there are significant differences between fibroadenomas and phyllodes tumours with regard to selected cytomorphological features. Study Design: A 10-year retrospective review was performed of patients who underwent excision of a fibroadenoma or phyllodes tumour and in whom a preoperative fine-needle aspiration was performed. The following cytological criteria were assessed: number of stromal and epithelial fragments, stromal-to-epithelial ratio, stromal cellularity, stromal borders, stromal atypia, and proportion of background wavy spindled cells. Patient age, t
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10

Pareek, Prashant, and Priyanka Pareek. "Giant juvenile fibroadenoma: a case report." International Surgery Journal 5, no. 4 (2018): 1589. http://dx.doi.org/10.18203/2349-2902.isj20181155.

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Breast Lumps are not a common occurrence in paediatric patients. When encountered, they call for a thorough workup and meticulous treatment plan. Like in adults, fibroadenomas can be seen in children. These are termed 'juvenile fibroadenomas'. When these are larger than 5cm or weigh more than 500gm, they can be called 'giant juvenile fibroadenomas'. These comprise 1-8% of breast lumps in adolescent population. We report here a case of a 10 years old girl who presented with a rapidly growing unilateral breast lump which provided a diagnostic dielemma but was diagnosed as giant juvenile fibroade
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11

Estevão, Rodrigo Augusto Fernandes, Afonso Celso Pinto Nazário, and Edmund Chada Baracat. "Effect of oral contraceptive with and without associated estriol on ultrasound measurements of breast fibroadenoma: randomized clinical trial." Sao Paulo Medical Journal 125, no. 5 (2007): 275–80. http://dx.doi.org/10.1590/s1516-31802007000500005.

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CONTEXT AND OBJECTIVE: Fibroadenomas are the most common benign tumors of the female breast. The aim of this study was to evaluate the proliferative activity of breast fibroadenoma as shown by ultrasound measurements, following administration of oral contraceptives with and without associated estriol. DESIGN AND SETTING: This was a randomized, double-blind, placebo-controlled clinical trial carried out in the Mastology Sector, Department of Gynecology, Universidade Federal de São Paulo. METHODS: We studied 33 women with fibroadenomas. Ten were placed in group 1 and took an oral contraceptive c
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12

Adamietz, B., L. Kahmann, P. Fasching, et al. "Differentiation Between Phyllodes Tumor and Fibroadenoma Using Real-Time Elastography." Ultraschall in der Medizin - European Journal of Ultrasound 32, S 02 (2011): E75—E79. http://dx.doi.org/10.1055/s-0031-1282024.

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Abstract Purpose: Phyllodes tumors (PT) are a rare entity accounting for less than 1 % of all breast lesions. They have a malignancy rate of 25 – 30 %. Differentiation from benign fibroadenomas is difficult using ultrasound, mammogram and MRI. The elastic characteristics of both tumors were examined using real-time elastography (RTE) to find specific patterns that make differentiation possible. Materials and Methods: From February 2007 to May 2009, a total of 620 women were examined by RTE. Histological diagnosis was achieved using core needle biopsy. 123 of the lesions were fibroadenomas, 8 w
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13

Ciurea, Anca Ileana, Hanelore Argentina Herţa, Cătălin George Iacoban, Bogdan Fetica, Liliana Rogojan, and Cristiana Augusta Ciortea. "Fibroadenomas and breast carcinoma: a possible answer to a frequently asked question. A pictorial essay." Medical Ultrasonography 20, no. 3 (2018): 385. http://dx.doi.org/10.11152/mu-1408.

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Fibroadenomas (FAs) are the most frequently encountered benign breast lesions in young women and due to the age of the patients, they are usually diagnosed by ultrasound. Although they rarely undergo malignant transformation, the patients remain concerned about the possibility of malignant transformation. The aim of this pictorial essay is to illustrate the appearance of classic and complex fibroadenomas, to discuss the risk factors and to highlight the imaging characteristics that raise the suspicion of malignant transformation. In other words, we try to answer, according to our experience an
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14

Pwee, Keng Ho. "VP44 Rapid Health Technology Assessment – High-Intensity Focused Ultrasound For Breast Fibroadenomas And Benign Thyroid Nodules." International Journal of Technology Assessment in Health Care 33, S1 (2017): 167–68. http://dx.doi.org/10.1017/s0266462317003270.

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INTRODUCTION:High-intensity focused ultrasound (HIFU) is a non-invasive ablative technique to treat breast fibroadenomas and benign thyroid nodules. A rapid Health Technology Assessment (HTA) was commissioned to inform the Changi General Hospital's decision on procuring a HIFU system.METHODS:A systematic literature search was conducted for systematic reviews, HTA reports and clinical practice guidelines on the clinical effectiveness of HIFU systems with the following PICO elements:Patients = patients with benign breast fibroadenomas or thyroid nodulesIntervention = HIFUComparator = conventiona
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15

Yagnik, Vipul. "Juvenile giant fibroadenoma." Clinics and Practice 1, no. 3 (2011): 49. http://dx.doi.org/10.4081/cp.2011.e49.

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Fibroadenomas are benign solid tumor associated with aberration of normal lobular development. Juvenile giant fibroadenoma is usually single and >5 cm in size /or >500 gms in weight. Important differential diagnoses are: phyllodes tumor and juvenile gigantomastia. Simple excision is the treatment of choice.
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16

Kairanna, Nikitha Valerina, Brijmohan Kumar Singh, and Pavithra P. "INCIDENTAL DETECTION OF CARCINOMA IN SITU IN FIBROADENOMA OF BREAST IN A YOUNG WOMAN: A RARE FINDING." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 1. http://dx.doi.org/10.22159/ajpcr.2018.v12i1.28326.

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Fibroadenoma is the most common benign tumor of the breast in young females. Breast cancer arising within a fibroadenoma is a rare phenomenon. The incidence of carcinoma within a fibroadenoma is reported to be between 0.1% and 0.3% in a screened population, with a peak age of occurrence between the 4th and 5th decade. We present a case of 29-year-old female with ductal carcinoma in situ in a background of fibroadenoma. There is a low percentage of fibroadenomas harboring carcinoma; however, all breast lumps should be seriously managed; extirpation and histological examination is recommended.
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17

Valerina Kairanna, Nikitha, Brijmohan Kumar Singh, and Pavithra P. "INCIDENTAL DETECTION OF CARCINOMA IN SITU IN FIBROADENOMA OF BREAST IN A YOUNG WOMAN: A RARE FINDING." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 1. http://dx.doi.org/10.22159/ajpcr.2019.v12i1.28326.

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Fibroadenoma is the most common benign tumor of the breast in young females. Breast cancer arising within a fibroadenoma is a rare phenomenon. The incidence of carcinoma within a fibroadenoma is reported to be between 0.1% and 0.3% in a screened population, with a peak age of occurrence between the 4th and 5th decade. We present a case of 29-year-old female with ductal carcinoma in situ in a background of fibroadenoma. There is a low percentage of fibroadenomas harboring carcinoma; however, all breast lumps should be seriously managed; extirpation and histological examination is recommended.
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18

Nwashilli, NJ, and I. Obahiagbon. "Giant Fibroadenoma in a Middle-Aged Woman Requiring Mastectomy: A Case Report." Annals of Health Research 6, no. 4 (2020): 456–62. http://dx.doi.org/10.30442/ahr.0604-11-109.

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Fibroadenomas are benign tumours of the breast. They are usually single, firm, rubbery masses, slow-growing and well encapsulated. Giant fibroadenomas are fibroadenomas at least 5cm in size or at least 500g in weight. The peculiarities of the index case include the massive size and weight of the breast, causing asymmetry and tissue distortion with little or no normal breast tissue on ultrasound scan. Also, such massive weight has not been reported in the literature as suggested by extensive search on databases such as Pubmed and Google Scholar. The main concern of the patient was the rapid gro
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19

Laxman, Santhosh, Pramod Sangolgi, Sharan Jabshetty, Arun Bhavikatti, and Arun Uttam. "Clinical profile of patients with fibroadenoma of breast." International Surgery Journal 5, no. 3 (2018): 1057. http://dx.doi.org/10.18203/2349-2902.isj20180830.

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Background: Fibroadenomas of breast are the commonest benign breast conditions. It is an attempt to study this common condition.Methods: Fifty cases with histologically diagnosed cases of fibroadenoma were included in the study and were compared with previous data from literature.Results: All the fifty patients included in this study were indoor patients. Maximum number of patient were in third decade (64%). Urban females have higher incidence of fibroadenoma (72%). Most fibroadenoma are unilateral (86%). Fibroadenoma are commonly present in upper lateral quadrant of breast (34%). Large sized
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20

Sanders, Linda M., Megan E. Daigle, Matthew Tortora, and Ryane Panasiti. "Transformation of benign fibroadenoma to malignant phyllodes tumor." Acta Radiologica Open 4, no. 7 (2015): 205846011559206. http://dx.doi.org/10.1177/2058460115592061.

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The transformation of a benign fibroadenoma into a phyllodes tumor is uncommon and unpredictable. We report the case of a 40-year-old woman with a core biopsy proven fibroadenoma that underwent transformation into a malignant phyllodes tumor after 3 years of size stability. We present ultrasound and magnetic resonance images, as well as pathology slides from core biopsy and surgical excision, to illustrate this transformation. It has been suggested that phyllodes tumors may be misdiagnosed as fibroadenomas by core biopsy. However, in this case, pathology supports correct initial diagnosis of f
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Tan, Wai Jin, Jie Yan, Shuoyu Xu, et al. "Second harmonic generation microscopy is a novel technique for differential diagnosis of breast fibroepithelial lesions." Journal of Clinical Pathology 68, no. 12 (2015): 1033–35. http://dx.doi.org/10.1136/jclinpath-2015-203231.

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Breast fibroepithelial lesions, including fibroadenomas and phyllodes tumours, are commonly encountered in clinical practice. As histological differences between these two related entities may be subtle, resulting in a challenging differential diagnosis, pathological techniques to assist the differential diagnosis of these two entities are of high interest. An accurate diagnosis at biopsy is important given corresponding implications for clinical decision-making including surgical extent and monitoring. Second harmonic generation (SHG) microscopy is a recently developed optical imaging techniq
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Chng, Tze Wei, Mihir Gudi, Swee Ho Lim, HuiHua Li, and Puay Hoon Tan. "Validation of the Singapore nomogram for outcome prediction in breast phyllodes tumours in a large patient cohort." Journal of Clinical Pathology 71, no. 2 (2017): 125–28. http://dx.doi.org/10.1136/jclinpath-2017-204568.

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AimsTo validate the Singapore nomogram for outcome prediction in breast phyllodes tumours in a large cohort of Singaporean patients, as previous validation studies were conducted on small numbers of patients. We also investigate the association of fibroadenomas and phyllodes tumours within a subset of our cohort.MethodsHistological parameters, surgical margin status and clinical follow-up data of 259 women diagnosed with phyllodes tumours were analysed. Patients with concurrent malignant or premalignant disease were excluded from the validation to minimise confounding influences. Biostatistics
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Eberspacher, Chiara, Francesco Nardi, Lisa Fralleone, and Domenico Mascagni. "Anal excision of perianal fibroadenoma: Expect the unexpected." SAGE Open Medical Case Reports 9 (January 2021): 2050313X2110355. http://dx.doi.org/10.1177/2050313x211035568.

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Breast fibroadenomas are a common benign tumour in women that may need to be surgically excised. A mammary-like fibroadenoma can exceptionally be found in the pathological report after an anal polyp removal. A 60-year-old woman presented with huge anal polyp of 25 mm. It was surgically removed transanally. Histologic examination revealed a breast fibroadenoma pattern with glandular structures. Proctologist specialists must be aware that mammary-like tumours are a possible differential diagnosis for anal masses despite their rarity in the literature.
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Andronic, O., D. Ion, Izabela Marin, Georgiana Radu, and D. N. Păduraru. "PECULIARITIES OF DIAGNOSIS IN THE PHYLLODES TUMOR." Journal of Surgical Sciences 2, no. 1 (2015): 29–33. http://dx.doi.org/10.33695/jss.v2i1.93.

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Phyllodes tumor (PT) is an uncommon and distinct category of breast cancer, being a particular form of intracanalicular fibroadenoma. A definitive diagnosis is difficult to make just based on imaging investigations and fine needle biopsy; also PTs are frequently misinterpreted as breast fibroadenomas. In the case of of a 26-year old woman with a suspected PT (based on clinical investigation) which was first diagnosed as a fibroadenoma using ultrasonography and preoperative biopsy, further investigation was needed. A limited resection was performed and the postoperative histopathology confirmed
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Agarwal, Puneet, Mayank Badkur, and Chirag Dausage. "Spontaneous infarction in fibroadenoma of breast: a rare pathological finding in a common pathological entity." International Surgery Journal 5, no. 3 (2018): 1145. http://dx.doi.org/10.18203/2349-2902.isj20180848.

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Fibroadenoma is one of the most prevalent benign tumour in adolescent women. It accounts for 20% of all benign breast tumours. Spontaneous infarction in fibroadenoma is very unwonted and mostly, it is associated with gravidity or lactation. Infarction can additionally occur as a complication of antecedent fine-needle aspiration biopsy. At the institution during 2-years period we incidentally found three such cases of spontaneous infarction of fibroadenoma over varied age groups which surprised us. So, reviewed the literature and presented our findings. Three fibroadenomas with features of cent
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Alam, KABM Taiful, Toufiqul Haque, Shamim Hossain, Kuntal Das, Tazul Lslam, and Helena Ahmed. "Giant Juvenile Fibroadenoma of Breast." Journal of Surgical Sciences 17, no. 2 (2019): 99–102. http://dx.doi.org/10.3329/jss.v17i2.43785.

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Giant juvenile fibroadenoma occurs in adolescent girls. These tumours become enormous in size and grow rapidly, though these tumours are mostly benign. These patients are almost always treated by breast conserving surgery. Here we present a case having unilateral giant juvenile fibroadenoma with bilateral multiple small fibroadenomas in an adolescent female aged 16years. The diagnosis of the patient was made on clinical examination, USG & FNAC. Confirmatory diagnosis was made by histopathology. We removed the giant one with "Swiss-Roll" procedure and others by simple enucleation. The aesth
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Audisio, Teresita, Francisco Crespo-Roca, Pedro Giraudo, and Rogelio Ramallo. "Fibroadenoma of the Vulva-Simultaneous With Breast Fibroadenomas and Uterine Myoma." Journal of Lower Genital Tract Disease 15, no. 1 (2011): 75–79. http://dx.doi.org/10.1097/lgt.0b013e3181de72e5.

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28

Ngbea, J. A., R. A. Vhritehire, B. A. Ojo, et al. "A Clinicopathologic Review of Fibroadenoma in Makurdi, North-Central Nigeria." Journal of BioMedical Research and Clinical Practice 1, no. 1 (2018): 81–86. http://dx.doi.org/10.46912/jbrcp.38.

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Fibroadenomas have been reported as the most common benign (non-cancerous) tumours of the female breast and are most common in women in their 20s and 30s. The clinical course and diagnosis of fibroadenoma as a benign breast lesion remains favourable except in cases of benign proliferative disease which has increased risk for breast cancer in about 0.01%. This retrospective study was to determine the prevalence of fibroadenoma in female breasts. A six year review of all patients with clinicopathologic diagnosis of fibroadenoma was carried out. A total of 110 cases of fibroadenoma constituting 3
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Ciftci, Ilhan, Tamer Sekmenli, Seda Ozbek, Mehtap Karamese, and Serdar Ugras. "Inframammarial Giant Fibroadenoma Removing and a Nipple-sparing Breast Reconstruction in an Adolescent: A Case Report." Prague Medical Report 116, no. 2 (2015): 161–66. http://dx.doi.org/10.14712/23362936.2015.54.

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Fibroadenomas are common, benign breast tumors that usually affect women in the second and third decade of life. Giant fibroadenomas often cause significant concern for the patient or family regarding malignant potential and altered breast development. Most fibroadenomas are benign. Local excision of small lesions through a circumareolar or inframammary incision rather than radical surgery is appropriate. Breast ultrasound represents the most commonly used imaging modality for the study of pediatric female breast masses and fibroadenomas. Detailed descriptions of the sonographic appearances of
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30

Meyer, J. E., T. H. Frenna, M. Polger, M. R. Sonnenfeld, and K. Shaffer. "Enlarging occult fibroadenomas." Radiology 183, no. 3 (1992): 639–41. http://dx.doi.org/10.1148/radiology.183.3.1584911.

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31

Amshel, Craig Edward, and Elena Sibley. "Multiple Unilateral Fibroadenomas." Breast Journal 7, no. 3 (2001): 189–91. http://dx.doi.org/10.1046/j.1524-4741.2001.007003189.x.

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Brownstone, Nicholas D., Karel-Bart Celie, Nitsana A. Spigland, and David M. Otterburn. "Pediatric Breast Fibroadenomas." Annals of Plastic Surgery 83, no. 5 (2019): 601–5. http://dx.doi.org/10.1097/sap.0000000000001717.

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33

Jayasinghe, Yasmin, and Patricia S. Simmons. "Fibroadenomas in adolescence." Current Opinion in Obstetrics and Gynecology 21, no. 5 (2009): 402–6. http://dx.doi.org/10.1097/gco.0b013e32832fa06b.

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34

Sibbald, Rachel. "Fibroadenomas in rats." Veterinary Nurse 12, no. 5 (2021): 220–23. http://dx.doi.org/10.12968/vetn.2021.12.5.220.

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This article looks at one of the most common reasons for presentation to practice in rats, mammary fibroadenomas. There is an extremely high incidence of this disease process in rats over 1 year of age and veterinary nurses have a duty of care towards these patients to provide up-to-date nursing techniques and engage in clinical discussions with veterinary surgeons to implement appropriate treatment plans. Surgical and medical options are explored along with tips for successful anaesthetic management of these patients. Although these neoplasms are benign, they are often fast growing and can si
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Lozada, John R., Kathleen A. Burke, Aoife Maguire, et al. "Myxoid fibroadenomas differ from conventional fibroadenomas: a hypothesis-generating study." Histopathology 71, no. 4 (2017): 626–34. http://dx.doi.org/10.1111/his.13258.

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36

Plaza, Michael J., Aswin V. Kumar, and Marcos A. Sanchez-Gonzalez. "Safety and Efficacy of Ultrasound-Guided Cryoablation for Benign Breast Fibroepithelial Lesions." Journal of Breast Imaging 1, no. 4 (2019): 324–28. http://dx.doi.org/10.1093/jbi/wbz047.

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Abstract Objective The purpose of this study is to evaluate the safety and efficacy of cryoablation for benign breast fibroepithelial lesions (FELs) that otherwise warrant surgical excision, including symptomatic fibroadenomas, growing fibroadenomas, and cellular FELs. Methods All patients from 2016–2018 who had ultrasound-guided cryoablation of a symptomatic and/or growing fibroadenoma or cellular fibroepithelial lesion were reviewed. The electronic medical record was reviewed for any procedure-related complications and reduction in mass volume by ultrasound and was recorded to assess for eff
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Mathew, J., DJ Crawford, M. Lwin, C. Barwick, and A. Gash. "Ultrasound-Guided, Vacuum-Assisted Excision in the Diagnosis and Treatment of Clinically Benign Breast Lesions." Annals of The Royal College of Surgeons of England 89, no. 5 (2007): 494–96. http://dx.doi.org/10.1308/003588407x187621.

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INTRODUCTION Ultrasound-guided, vacuum-assisted biopsy has a definitive role in the diagnosis of breast lesions. Its role in the treatment of benign breast lesions like fibroadenomas has not been established. PATIENTS AND METHODS This is a retrospective review of patients undergoing ultrasound-guided, vacuum-assisted biopsy for clinically benign breast lesions. The procedures were performed in all cases by two consultant radiologists with special interest in breast radiology between February 2002 and January 2004. Patients were followed up in the clinic 6 weeks after the procedure. RESULTS Sev
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Biswas, SK, ASM Tanjihur Rahman, AC Paul, MSI Mollah, and V. Chowdhury. "Giant Juvenile Fibroadenoma of the Breast: Report of 2 Cases." Faridpur Medical College Journal 7, no. 1 (2012): 42–45. http://dx.doi.org/10.3329/fmcj.v7i1.10298.

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Giant fibroadenomas are benign tumors, but their rapid growth and large size together with their rarity may determine difficulties in the clinical approach. The authors present 2 cases of giant juvenile fibroadenoma of the breast in girls aged 14 and 16 years, and the respective diagnostic workup and conservative surgical treatment. The diagnosis was made on fine needle aspiration cytology which was confirmed on histopathology. These tumours are almost always benign and should be treated with breast conserving surgery.DOI: http://dx.doi.org/10.3329/fmcj.v7i1.10298Faridpur Med. Coll. J. 2012;7(
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Zhang, Rong-rong, Scott Bevan, Ping Sun, Jim Z. Lu, and Yan Peng. "Unusual Presentation of Multiple Fibroadenomas in Bilateral Breasts and Axillary Accessory Breast." Breast Cancer: Basic and Clinical Research 6 (January 2012): BCBCR.S9512. http://dx.doi.org/10.4137/bcbcr.s9512.

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We report an extremely rare case with a total of 50 fibroadenomas simultaneously presented in bilateral breasts and left axillary accessory breast, up to 8 cm in size, in a 20 year-old Chinese woman. The histopathologic and immunophenotypic features of the fibroadenomas are described and possible underlying pathogenesis is discussed. To our knowledge, this is the first case with such a large number of bilateral multiple breast fibroadenomas in a young female reported in the literature.
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Hota, Subhransu Kumar, Ranjana Giri, Hardik Kabra, Devika Chauhan, Prita Pradhan, and Pran Singh Pujari. "Complex fibroadenoma with focal ossification- an enigmatic finding in a less common tumor." International Surgery Journal 8, no. 5 (2021): 1650. http://dx.doi.org/10.18203/2349-2902.isj20211851.

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Breast lumps have diverse causes including benign as well as malignant lesions. Fibroadenoma (FA) is a common cause of breast lump. Complex fibroadenomas, a particular subtype, pose diagnostic dilemmas due to confusing the radiological findings and hold higher incidence of transformation to malignancy. A 49 year old female presented with a painless lump in right breast for 2 years which appeared calcified on radiology. Excision biopsy was performed which grossly revealed an encapsulated grey-white firm to hard with cystic areas. Microscopically the sections showed a well encapsulated fibroepit
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Bellynda, Monica, and Kristanto Yuli Yarso. "Patient Satisfaction in the Complete Removal of Giant Breast Fibroadenoma under Vacuum-Associated Breast Biopsy Procedure." Open Access Macedonian Journal of Medical Sciences 9, no. C (2021): 40–42. http://dx.doi.org/10.3889/oamjms.2021.5929.

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INTRODUCTION: Fibroadenomas are one of the most common benign tumors of the breast in the adolescent population. They account for 68% of all breast masses and 44–94% of all biopsied breast lesions. Fibroadenomas can range from asymptomatic masses to painful and rapidly growing tumors that can cause significant esthetic distortions of the breast. With breast examinations becoming common in women as young as their 20s, excision of benign breast tumors using vacuum-assisted breast biopsy (VABB) became more common. The VABB procedure with ultrasound guiding is still used for removal benign breast
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Pinto, Joana, Ana Teresa Aguiar, Hálio Duarte, Filipa Vilaverde, Ângelo Rodrigues, and José Luís Krug. "Simple and Complex Fibroadenomas." Journal of Ultrasound in Medicine 33, no. 3 (2014): 415–19. http://dx.doi.org/10.7863/ultra.33.3.415.

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Roberts, Catherine, K. Rebecca Hunt, Laurie Fajardo, and Tim Hunter. "FIBROADENOMAS IN POSTMENOPAUSAL WOMEN." Investigative Radiology 27, no. 12 (1992): 1100. http://dx.doi.org/10.1097/00004424-199212000-00107.

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Littrup, Peter J., Laurie Freeman-Gibb, Aleodor Andea, et al. "Cryotherapy for Breast Fibroadenomas." Radiology 234, no. 1 (2005): 63–72. http://dx.doi.org/10.1148/radiol.2341030931.

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Greenberg, Ron, Yehuda Skornick, and Ofer Kaplan. "Management of breast fibroadenomas." Journal of General Internal Medicine 13, no. 9 (1998): 640–45. http://dx.doi.org/10.1046/j.1525-1497.1998.cr188.x.

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Wahab, Tajudeen A., Hanna Uwakwe, Rilwan Aransi, Humuyan Kabir Khan, and Maher Jumah. "Biopsy proven fibroadenomas- how frequent is pathologies other than fibroadenomas post-excision?" International Journal of Medicine 6, no. 1 (2018): 13. http://dx.doi.org/10.14419/ijm.v6i1.9457.

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Introduction: Breast fibroadenoma (FA) is a common benign tumour diagnosed usually through ‘Triple Assessment’. FA that is large, symptomatic or exhibit interval growth is recommended for excision. Some patients question the need for excision if preoperative assessment concluded FA while others want to be absolutely sure that the ‘FA’ that is not excised and managed conservatively is absolutely a FA. The aim of the present study is to ascertain the magnitude of unexpected post-excision pathology when a biopsy proven FA is excised according to the current UK guideline.Materials and Method: Retr
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Islam, Shariful, Sabrina Saroop, Vinoo Bheem, and Vijay Naraynsingh. "Largest giant juvenile fibroadenoma of the breast." BMJ Case Reports 12, no. 1 (2019): e227277. http://dx.doi.org/10.1136/bcr-2018-227277.

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Juvenile giant fibroadenoma is a rare benign tumour of the breast accounting for 0.5% of all fibroadenomas. The presentation can be very dramatic and may result in breast deformity and may mimic a rare malignant tumour. It is indeed a great challenge to provide the best treatment for these patients in terms of clinical and psychological care. Meticulous surgical planning is required to ensure a fine balance between adequate resection and the best cosmetic outcome for a developing breast. Every effort should be made to preserve the developing breast irrespective of the size of the tumour as it
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Bineta Keneme та Pape Mbacké Sembene. "Pathogenicity of CYP17α mutations in the occurence of uterine fibroids and breast fibroadenomas". International Journal of Biological and Pharmaceutical Sciences Archive 1, № 2 (2021): 085–99. http://dx.doi.org/10.30574/ijbpsa.2021.1.2.0030.

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Background. Uterine fibroids and breast fibroadenomas are a real public health problem. Despite the efforts made, the etiological factors are still unknown. In addition, these tumors share histopathological similarities, including a higher prevalence in black women. To better understand the factors involved, we set out to assess the genetic characteristics of uterine fibroids and breast fibroadenomas in Senegalese women using CYP17α genes. Results. For the CYP17α gene, 196 mutations were found among which, 65 are specific to uterine fibroids, 112 mutations specific to breast fibroadenomas and
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Yeboah, Ivan B., Selassie Wonder King Hatekah, Yvonne Kafui Konku-Asase, Abu Yaya, and Kwabena Kan-Dapaah. "Destruction of Fibroadenomas Using Photothermal Heating of Fe3O4 Nanoparticles: Experiments and Models." Applied Sciences 10, no. 17 (2020): 5844. http://dx.doi.org/10.3390/app10175844.

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Conventionally, observation (yearly breast imaging) is preferred to therapy to manage small-sized fibroadenomas because they are normally benign tumors. However, recent reports of increased cancer risk coupled with patient anxiety due to fear of malignancy motivate the need for non-aggressive interventions with minimal side-effects to destroy such tumors. Here, we describe an integrated approach composed of experiments and models for photothermal therapy for fibroadenomas destruction. We characterized the optical and structural properties and quantified the heat generation performance of Fe3O4
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Chaudhari, Dr Bharat Muljibhai, and Dr Ashish N. Madiya. "Clinic Pathological Evaluation of Benign Breasts Lesion." Tropical Journal of Pathology and Microbiology 7, no. 1 (2021): 40–43. http://dx.doi.org/10.17511/jopm.2021.i01.06.

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Introduction: Benign breast lesions are more common than malignant tumours. Hence recognizingthem is important from the viewpoints of therapy and prognosis. Methodology: The materials forthe study comprised of resected specimens of breast lesions received in the pathology departmentKarnataka Institute of Medical Sciences, Hubballi from May 2010 to April 2015. Results: A total of600 cases of benign breast lesions were recorded. Fibroadenoma was the commonest benign breastlesions comprising 70.82%, followed by fibrocystic disease 12%, benign phyllodes tumour 8.3%.The majority of benign breast le
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