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Journal articles on the topic 'G12'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Cheddour, Zakariae, Abdelhakim Chillali, and Ali Mouhib. "Elliptic curves over imaginary biquadratic number fields of class number one." Gulf Journal of Mathematics 19, no. 1 (2025): 75–92. https://doi.org/10.56947/gjom.v19i1.2430.

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This research investigates elliptic curves within an imaginary biquadratic number field ℵ of class number one. Our study focuses on the existence of torsion subgroups isomorphic to G11, G13, G14, G15, G16, G18, G2 ⊕ G10, and G2 ⊕ G12 over ℵ.

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Hoque, MA, and S. Mahmud. "Morphological Characterization and Evaluation of Nineteen Gladiolus Germplasm." Annals of Bangladesh Agriculture 23, no. 2 (2019): 37–48. http://dx.doi.org/10.3329/aba.v23i2.50054.

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Nineteen gladiolus germplasms were characterized and evaluated in the Research Field of the Department of Horticulture, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, during November 2017 to May 2018 for identifying suitable line(s) to release as a variety for commercial cultivation. The accession G8 produced the highest number of shoots (3.3) and effective shoots (3.0) per hill. The accessions that produced flower stalk within 75 days of planting included BARI gladiolus- 3 (G1, 58.7 days), G2 (62.3 days), G3 (65.7 days), BARI gladiolus- 5 (G4, 61.3 days), G5 (55.7 days),

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3

Djarot Sasongko Hami Seno, Mohamad Rafi, Maria Bintang, Popy Asri Kurniatin, and Waras Nurcholis. "Stabilitas Laju Fotosintesis dan Produktivitas Rimpang Genotipe Curcuma aeruginosa dan Curcuma zanthorrhiza." Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) 48, no. 1 (2020): 89–96. http://dx.doi.org/10.24831/jai.v48i1.30100.

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Curcuma aeruginosa Roxb. rhizome is an essential herb material with significant antimicrobial, anticancer, and antioxidant activities. Thus, it is important to search for C. aeruginosa plant that has the rhizome yield trait with more excellent stability in changing environmental situations. This research aimed to evaluate the genotype x environment interaction using additive main effects and multiple interaction (AMMI) analysis for photosynthetic rate and rhizome yield of C. aeruginosa genotypes. Twenty clones of C. aeruginosa plus three control varieties of C. zanthorrhiza Roxb. were evaluate

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Medina, Alberth David Correa, Andréia Bolzan de Paula, Suzana Beatriz Portugal de Fucio, Regina Maria Puppin-Rontani, Lourenço Correr-Sobrinho, and Mário Alexandre Coelho Sinhoreti. "Marginal adaptation of indirect restorations using different resin coating protocols." Brazilian Dental Journal 23, no. 6 (2012): 672–78. http://dx.doi.org/10.1590/s0103-64402012000600008.

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This study evaluated the influence of material combinations used in the resin coating technique (RCT) on the marginal adaptation of indirect restorations with gingival margins in enamel (EM) and cement (CM). Eighty third-molars were used. Two cavities were prepared in each tooth. The cavities were distributed into 16 groups. Cavities with EM were filled with the following material combinations: G1: Single-Bond 2 (Sb2), G2: Sb2 + Bond/Scotchbond-Multipurpose (Sb2B), G3: Sb2 + Filtek-Flow Z350 (Sb2Fl), G4: Scotchbond-Multipurpose (SBMP), G5: Clearfil-S3 (CS3), G6: CS3 + Bond/Clearfil-SE Bond (CS

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Guiloff, Gloria D., and Helga Kolb. "Ganglion cell types of the turtle retina that project to the optic tectum: Intracellular HRP injections of retrogradely, rhodamine-marked cell bodies." Visual Neuroscience 8, no. 4 (1992): 295–313. http://dx.doi.org/10.1017/s0952523800005046.

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AbstractThe turtle retina has been shown to have a variety of different morphological ganglion cell types as well as distinct physiological ganglion cell types. The major projection of the retina to the brain in nonmammalian vertebrates is to the optic tectum. In this study, we address the question of which retinal ganglion cell types project to the optic tectum in the turtle.Fluorescent rhodamine-labeled microspheres were used to trace the retinal ganglion cell projection to the superficial layers of the optic tectum. The fluorescent ganglion cell somata, retrogradely marked by transport from

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Arter, Zhaohui, Misako Nagasaka, and Sai-Hong Ignatius Ou. "Survey of actionable driver mutations KRAS and EGFR in non–small cell lung cancer to evaluate coexisting splicing gene and pathway mutations: A CBioportal database analysis." Journal of Clinical Oncology 42, no. 16_suppl (2024): 8561. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.8561.

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8561 Background: Molecularly targeted therapies have advanced treatment for certain cancers, such as lung cancer with specific EGFR or KRAS mutations. However, oftentimes the tumor becomes eventually treatment resistant. This may be partly because cancers driven by EGFR/KRAS mutations may also harbor additional co-occurring genetic alterations. In non-small cell lung cancer (NSCLC), aberrations in RNA splicing pathways have shown substantial implications for tumor behavior and therapeutic responsiveness. Our study focuses on elucidating the interplay between RNA splicing defects and prominent

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Grell, Peter, Stanislav Batko, Alina Pirsthuk, et al. "RAS mutation specific survival in patients with metastatic colorectal cancer treated with trifluridine/tipiracil." Journal of Clinical Oncology 42, no. 3_suppl (2024): 197. http://dx.doi.org/10.1200/jco.2024.42.3_suppl.197.

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197 Background: Trifluridine/tipiracil (T/T) is effective in patients with pretreated metastatic colorectal cancer (mCRC). RAS mutational status could predict magnitude of T/T effect (van de Haar et al, Nat Med. 2023), but the data are conflicting. Methods: We retrospectively reviewed the clinical data of 402 patients consecutively treated with T/T in two institutions in the Czech Republic and analysed the potential predictive value of different RAS mutations. Results: Baseline characteristics: median age 65 (range 28-84), female 32.8%, ECOG PS 0 in 32.8% and 1 in 64.9%, primary tumor location

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Elixon, S., Y. Mohd Rafii, R. Asfaliza, J. Mashitah, and R. Shairul Izzan. "Genotype × environment interaction and stability analysis on physicochemical traits of Malaysian rice hybrid across the environments." April 2022, no. 16(04):2022 (April 1, 2022): 512–21. http://dx.doi.org/10.21475/ajcs.22.16.04.p3468.

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In the development of new varieties, physicochemical properties such as grain quality, milling, and chemical content are important. Twenty rice hybrids were tested in various environments in this study. Using multivariate and univariate models, the major goal is to identify rice hybrids with acceptable physicochemical properties and high stability. According to the ANOVA, variance due to season×genotype×location revealed a significant difference in length to width ratio, head rice recovery, and amylose content. Milled grain length and width varied from 6.64 to 7.32 mm and 1.78 to 2.06 mm, resp

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Nurdin, Nurdin, Erni Susanti, Hafizh Al-Kautsar Aidilof, and Dadang Priyanto. "Comparison of Naive Bayes and Dempster Shafer Methods in Expert System for Early Diagnosis of COVID-19." MATRIK : Jurnal Manajemen, Teknik Informatika dan Rekayasa Komputer 22, no. 1 (2022): 215–28. http://dx.doi.org/10.30812/matrik.v22i1.2280.

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COVID-19 is a respiratory infection disease caused by the corona virus. Transmission of this virus can spread very quickly so that the number of cases of the corona virus continues to grow and becomes an epidemic that spreads not only in Indonesia but also in other countries in the world. The purpose of this study is to build an expert system that is able to diagnose Covid-19 early by using a comparison of the Nave Bayes method and the Dempster Shafer method. The amount of data used in this study is 550 data, consisting of 500 training data and 50 testing data. While the variables used are sym

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Norton, Carter, Jarrod Smith, Zach Rubnitz, et al. "Clinical impact of KRAS mutations in metastatic pancreatic ductal adenocarcinoma (PDAC)." Journal of Clinical Oncology 42, no. 3_suppl (2024): 619. http://dx.doi.org/10.1200/jco.2024.42.3_suppl.619.

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619 Background: Mutations in the KRAS oncogene occur in most PDAC and lead to the activation of the KRAS protein. Little is known about the differential impact of KRAS mutations on the outcomes of patients receiving standard of care cytotoxic treatments for metastatic disease. KRAS inhibitors are emerging as promising options for this disease and understanding the impact of distinct KRAS mutations in patient outcomes is needed. Methods: This study used the nationwide Flatiron Health electronic health record (EHR)-derived de-identified database from 5,369 patients. Adult patients with diagnosis

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Karimizadeh, R., P. Pezeshkpour, A. Mirzaee, M. Barzali, P. Sharifi, and M. R. Safari Motlagh. "Stability analysis for seed yield of chickpea (<i>Cicer arietinum</i> L.) genotypes by experimental and biological approaches." Vavilov Journal of Genetics and Breeding 27, no. 2 (2023): 135–45. http://dx.doi.org/10.18699/vjgb-23-19.

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A range of environmental factors restricts the production of chickpea; therefore, introducing compatible cultivars to a range of environments is an important goal in breeding programs. This research aims to find high-yielding and stable chickpea genotypes to rainfed condition. Fourteen advanced chickpea genotypes with two control cultivars were cultivated in a randomized complete block design in four regions of Iran during 2017–2020 growing seasons. The first two principal components of AMMI explained 84.6 and 10.0 % of genotype by environment interactions, respectively. Superior genotypes bas

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Desheva, Gergana, Evgeniya Valchinova, and Albena Pencheva. "Parametric and non-parametric methods for the evaluation of winter rye genotypes by grain yield stability." Journal of Agricultural Sciences, Belgrade 70, no. 1 (2025): 1–19. https://doi.org/10.2298/jas2501001d.

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The analysis of yield stability has become increasingly relevant in recent years due to changing climatic conditions that negatively affect crop yields. It is of utmost importance for farmers to cultivate widely adaptable and yield-stable varieties with high yield potential, as this determines economic predictability and mitigates their risk. Stability is also crucial for plant breeders to create genotypes adapted to a wide range of diverse environments. The aim of this study was to identify high-yielding, stable and adaptive rye landraces and cultivars for commercial and breeding purposes. Th

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Ash, Leonard J., Ottavia Bourdain, Dennis Lam, Shlomo S. Pallas, and Andrew L. Wolfe. "Abstract 1669: KRAS G12X mutants display differential preferences in downstream effector binding." Cancer Research 84, no. 6_Supplement (2024): 1669. http://dx.doi.org/10.1158/1538-7445.am2024-1669.

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Abstract KRAS is among the most frequently mutated oncogenic driver proteins in human cancers including lung, colorectal, and pancreatic cancers. Activating KRAS mutants cause increased cell proliferation through direct binding and overactivation of effector proteins. Effector activation preference is driver mutation specific, as KRAS G12D and G12C purportedly bind both RAF and PI3K, whereas G12R has been reported to bind RAF but not PI3K. The mechanisms of effector binding of G12S action are under-investigated. Furthermore, most KRAS mutations remain clinically untreatable, as clinically appr

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Al-Ashkar, Ibrahim. "Multivariate Analysis Techniques and Tolerance Indices for Detecting Bread Wheat Genotypes of Drought Tolerance." Diversity 16, no. 8 (2024): 489. http://dx.doi.org/10.3390/d16080489.

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Drought stress is one of the biggest hardships in wheat cultivation because of the strong negative relationship between water deficit and crop yields owing to a lower grain weight, a shorter grain-filling period, a slower grain-filling rate, and reduced grain quality. Genotype–environment interaction (GEN:ENV) generates hardships in selecting wheat genotypes and ideotypes due to biased genetic estimates. Diverse strategies have been proposed to respond to the urgent need for concurrent improvements in yield performance and stability. This study’s purpose was to appraise genetic variation and G

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Kumar, BM Dushyantha, AP Purushottam, P. Raghavendra, T. Vittal, KN Shubha, and R. Madhuri. "Genotype environment interaction and stability for yield and its components in advanced breeding lines of red rice (Oryza sativa L.)." Bangladesh Journal of Botany 49, no. 3 (2020): 425–35. http://dx.doi.org/10.3329/bjb.v49i3.49328.

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Effects of genotype, environment and their interaction for grain yield and yield attributing characters in 20 advanced breeding lines of rice across six environments was investigated. Yield stability and adaptability of yield performance were analyzed by Eberhart and Russel model and (GGE) bi-plot. The AMMI analysis of variance indicated that mean squares due to genotypes, location and genotype location contributed per cent 59.08, 5.79 and 21.63, respectively for total variability in grain yield per hectare. Estimates of GGE bi-plot revealed that the lines G1, G3, G11, G13, G15, G12, G16, G7 a

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Sabaghnia, Naser, Mohtasham Mohammadi, and Rahmatollah Karimizadeh. "Yield stability of performance in multi-environment trials of barley (Hordeum vulgare L.) genotypes." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 61, no. 3 (2013): 787–93. http://dx.doi.org/10.11118/actaun201361030787.

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Fourteen new breeding lines obtained from the barley breeding programs, cultivar Izeh and one local check genotype were evaluated for yield stability at eleven environments. The combined analysis of variance indicated the significance of the environments, genotypes and genotype by environment interaction. According to the environmental variance (EV) and coefficient of variation (CV), genotypes G2, G12, G13 and G14 while based on Wi, P, PP and SH parameters genotypes G4, G10 and G12 were the most stable ones. Regarding both PI and MSPI parameters, genotypes G2, G10 and G11 were the most stable.

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Szabolcs, Annamaria, Timothy J. Break, Isaac H. Shin, Seth B. Harkins, and Jacob N. Wohlstadter. "Abstract 4351: Multiplex detection of G12/G13 KRAS mutations with an electrochemiluminescent hybridization assay." Cancer Research 83, no. 7_Supplement (2023): 4351. http://dx.doi.org/10.1158/1538-7445.am2023-4351.

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Abstract Purpose: Oncogenic Kirsten rat sarcoma virus (KRAS) mutations are the most prevalent cancer mutations in all human tumors. Also, genotyping the KRAS gene has become increasingly important with the emergence of new evidence highlighting differences in downstream signaling pathways, tumor microenvironment composition, treatment responses and prognoses linked to specific single nucleotide polymorphisms (SNPs) in the G12 or G13 codons. FDA approval of G12C-specific anti-KRAS drugs highlights the importance of the development of reliable SNP assays to interrogate the mutation status in a t

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S., Elixon, Mohd Rafii Y., Asfaliza R., Mashitah J., and Shairul Izzan R. "Multivariate analysis of GGE and AMMI biplot graph to investigate geno-type by environment interaction of rice hybrids at multiple locations in Malaysia." Journal of Agriculture and Applied Biology 4, no. 1 (2023): 48–62. http://dx.doi.org/10.11594/jaab.04.01.06.

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This study was conducted to investigate the genotype by environment (G×E) interaction of 20 rice hybrids tested in eight environments which include four locations and two different cropping seasons in Malaysia. The parameter was observed on yield per ha, number of panicles per plant, number of filled grains per panicle, and thousand-grain weight. Data analysis was used by ANOVA and stability measurement according to AMMI and GGE biplot graph. The ANOVA indicated that all studied phenotypic showed significantly different in variance genotypes, season, location, location × season, genotype × sea

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Oh, Sangmin S., and Jessica A. Wachter. "Cross-Sectional Skewness." Review of Asset Pricing Studies 12, no. 1 (2021): 155–98. http://dx.doi.org/10.1093/rapstu/raab023.

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Abstract What distribution best characterizes the time series and cross-section of individual stock returns? To answer this question, we estimate the degree of cross-sectional return skewness relative to a benchmark that nests many models considered in the literature. We find that cross-sectional skewness in monthly returns far exceeds what this benchmark model predicts. However, cross-sectional skewness in long-run returns in the data is substantially below what the model predicts. We show that fat-tailed idiosyncratic events appear to be necessary to explain skewness in the data. (JEL, G10,

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Pant, Shubham, Sumit Kar, Kevin K. Lin, and Ethan Ahler. "Frequency and incidence of oncogenic RAS mutations in patients with metastatic pancreatic ductal adenocarcinoma: Derived from the real-world evidence database Foundation Medicine Insights." Journal of Clinical Oncology 43, no. 4_suppl (2025): 777. https://doi.org/10.1200/jco.2025.43.4_suppl.777.

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777 Background: Approximately 60,000 patients are diagnosed with pancreatic cancer in the United States annually, with half of all cases diagnosed at the metastatic stage. 1 The most common type, pancreatic ductal adenocarcinoma (PDAC), accounts for ~90% of all pancreatic cancers 2 and is characterized by frequent KRAS oncogenic mutations. Newer investigational therapeutics target HRAS and NRAS, in addition to KRAS. To comprehensively characterize the incidence of RAS mutations in patients with PDAC, we analyzed mutational frequency data from the Foundation Medicine Insights (FMI) database. Me

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Regis, Jiuli Ani Vilas Boas, João Antonio da Costa Andrade, Adriano dos Santos, et al. "Adaptability and phenotypic stability of sugarcane clones." Pesquisa Agropecuária Brasileira 53, no. 1 (2018): 42–52. http://dx.doi.org/10.1590/s0100-204x2018000100005.

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Abstract: The objective of this work was to select superior sugarcane (Saccharum officinarum) clones with good stability and adaptability, considering the genotype x environment interaction in two productive cycles. Twenty-five early clones plus five control clones were evaluated during two cuts (ratoon cane and plant cane) in 24 environments. A randomized complete block design was used, with three replicates. Tons of stems per hectare and tons of pol per hectare were evaluated. To verify adaptability and stability, the bisegmented regression and the multivariate (AMMI and GGE biplot) methods

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Kumar, G. Senthil, S. Manonmani, D. R. Harini, et al. "Evaluation of Rice Genotypes for Tolerance to Imazethapyr Herbicide in Direct-Seeded Rice Systems." Journal of Experimental Agriculture International 47, no. 1 (2025): 265–72. https://doi.org/10.9734/jeai/2025/v47i13227.

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Aims: The aim of this study was to evaluate the resistance of different rice genotypes to the herbicide imazethapyr. Study Design: Pot culture experiment. Place and Duration of Study: The experiment was conducted in pot culture at the Department of Agronomy, Tamil Nadu Agricultural University, Coimbatore, Kharif 2024. Methodology: Pot culture experiment was conducted with three replications by using fourteen rice genotypes (G1, G2, G3, G4, G5, G6, G7, G8, G9, G10, G11, G12, G13, and G14) to assess the phyto-toxicity tolerance. A herbicide spray was applied at the 2-3 leaf stage of weeds in the

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Desheva, Gergana, and Evgeniya Valchinova. "Evaluation of Yield Stability and Adaptability of Oat Genotypes (Avena sativa L.)." Poljoprivreda 30, no. 1 (2024): 3–12. http://dx.doi.org/10.18047/poljo.30.1.1.

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This study’s main objectives were (i) to determine the stability of oat genotypes for the grain yield (t ha-1), (ii) to investigate the relationship of stability parameters with the grain yield in the analyzed set of genotypes, and (iii) to identify the high-yielding, stable, and adaptive oat genotypes for breeding purposes. The study was conducted during the 2015-22 period and involved fourteen winter oat genotypes maintained in the Bulgarian Seed Gene Bank. The trial was laid out in a randomized block design of variants in three replications and an experimental plot size of 10 m2. Sixteen gr

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TOMIĆ, Dalibor, Mirjana RADOVANOVIĆ, Miloš MARJANOVIĆ, et al. "Divergence analysis of Cucurbita pepo L. population for seed oil production." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 52, no. 4 (2024): 13907. https://doi.org/10.15835/nbha52413907.

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The work aim was to analyze the divergence of the genotypes of common pumpkin (Cucurbita pepo L.) and to select suitable parents for the breeding program to increase the production of cold-pressed oil. For the analysis of the yield components of the genotypes, the fruits of the common pumpkin were collected in autumn and winter 2021-2022 in central and Western Serbia. There were 19 genotypes (G1-G19) collected randomly in a larger geographical area. The following analyses were carried out: fruit weight, seed weight per fruit, seed number per fruit, thousand seeds weight, percentage of seeds in

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Vaezi, Behrouz, Naser Sabgahnia, Asghar Mehraban, and Hamid Hatami-Maleki. "Nonparametric Analysis of Genotype Grain Yield Performance of Barley Trials Based on Ranks." Romanian Agricultural Research 39 (2022): 111–21. http://dx.doi.org/10.59665/rar3911.

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Plant breeding has been concerned with genotype by environment (GE) interaction and high yielding genotypes with stable performance are desirable while this target is difficult to achieve due to high environmental variations and unpredictable GE interaction. Stability of grain yield performance of 18 barley genotypes was evaluated at 5 locations for 3 years in the rainfed conditions and it was studied through 25 nonparametric stability methods. Four nonparametric tests indicated highly significant GE interaction due to differential performance of genotypes across fifteen environments. Regardin

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Shi, Shuhua, Linqi Zheng, Yonglian Ren, and Ziyu Wang. "Impacts of Mutations in the P-Loop on Conformational Alterations of KRAS Investigated with Gaussian Accelerated Molecular Dynamics Simulations." Molecules 28, no. 7 (2023): 2886. http://dx.doi.org/10.3390/molecules28072886.

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G12 mutations heavily affect conformational transformation and activity of KRAS. In this study, Gaussian accelerated molecular dynamics (GaMD) simulations were performed on the GDP-bound wild-type (WT), G12A, G12D, and G12R KRAS to probe mutation-mediated impacts on conformational alterations of KRAS. The results indicate that three G12 mutations obviously affect the structural flexibility and internal dynamics of the switch domains. The analyses of the free energy landscapes (FELs) suggest that three G12 mutations induce more conformational states of KRAS and lead to more disordered switch do

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Verma, Ajay, and Gyanendra Pratap Singh. "Decipher interactions effects of wheat genotypes evaluated in Northern Hills Zone by AMMI, BLUP and Non Parametric measures." Ecology, Environment and Conservation 28 (2022): 16–20. http://dx.doi.org/10.53550/eec.2022.v28i07s.004.

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Significant variations due to environments 38.3%, GxE interactions 32.1%, and genotypes 10.9% were observed by AMMI analysis. ASV1 and ASV measures recommended G13, G2, G11 genotypes. Based on 97.8% of GxE interactions sum of squares MASV1 identified G13, G3, G7 whereas MASV settled for G13, G1, and G7 genotypes. BLUP-based measures HMGV, RPGV, HMRPGV identified G9, G6, G13 genotypes. Non parametric composite measure NPi (1) observed suitability ofG3, G13, G12 whereas NPi (2), NPi (3), NPi (4) identified G3, G10, G12 genotypes. Biplot analysis observed 65.4% of the total variation in the consi

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Fouladvand, Mahmoud, Asa Ebrahimi, Mahdi Rahaie, and Vahid Shariati. "The Stability of Sugar Yield in Promising Sugarcane Genotypes (Saccharum officinarum L.)." International Journal of Agronomy 2024 (January 18, 2024): 1–12. http://dx.doi.org/10.1155/2024/5540112.

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Stability analysis is one of the most important steps that a breeder should use to release a new variety for a region. To identify and introduce the best sugarcane genotypes, an experiment with 26 promising Sugarcane genotypes along with four commercial varieties was planned and implemented during 2017–2019. This study aimed to determine a promising stable sugarcane genotype for the sugarcane-growing areas of Khuzestan Province in Iran. The effects of genotype × environment interactions on the sugar yield of 26 promising sugarcane genotypes and four standard varieties as controls were investig

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Mulyani, Muhammad Syafi'i, Lutfi Afifah, and Budi Irfan. "INTENSITAS SERANGAN DAN FLUKTUASI POPULASI HAMA ULAT GRAYAK (Spodoftera frugiperda J.E Smith) PADA BEBERAPA GALUR TETUA JAGUNG MANIS (Zea mays saccharata Sturt) MS-UNSIKA MUTAN GENERASI M7." Jurnal Agrotech 14, no. 1 (2024): 63–69. http://dx.doi.org/10.31970/agrotech.v14i1.163.

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Hama ulat grayak (Spodoftera frugiperda J.E Smith) merupakan hama penting pada tanaman jagung, penanaman varietas tahan merupakan salah satu cara untuk pengendalian serangan hama tanaman. Tujuan dari penelitian untuk mendapatkan galur tetua jagung manis MS-Unsika mutan generasi M7 yang memiliki ketahanan terhadap serangan hama ulat grayak. Metode menggunakan Rancangan Acak Kelompok (RAK) faktor tunggal. Perlakuan terdiri dari 10 genotipe yaitu SR 1 (Galur SR Latan), M6 (SR Latan di iradiasi sinar gamma dosis 200 gy) M8 (SR Sweet di iradiasi sinar gamma dosis 200 gy) M9 (SR Bonanza di iradiasi

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Esan, Vincent Ishola, Idowu Arinola Obisesan, and Timothy Oyebamiji Ogunbode. "Root System Architecture and Physiological Characteristics of Soybean (Glycine max L.) Seedlings in Response to PEG6000-Simulated Drought Stress." International Journal of Agronomy 2023 (July 22, 2023): 1–13. http://dx.doi.org/10.1155/2023/9697246.

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The production of soybean is restricted in sub-Saharan Africa by several stress conditions, including drought because its production is exclusively rain-fed. Identifying drought resistant varieties is of paramount importance. Thus, the objectives of this work were to (i) evaluate the effect of polyethylene glycol 6000 (PEG6000) on soybean at the seedling stage, (ii) determine the root system architecture and physiological characters to water deficit stress, and (iii) establish the correlation among the quantitative variables responsible for drought tolerance in soybean varieties. Twenty soybea

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Al-Ashkar, Ibrahim, Mohammed Sallam, Khalid F. Almutairi, Mohamed Shady, Abdullah Ibrahim, and Salem S. Alghamdi. "Detection of High-Performance Wheat Genotypes and Genetic Stability to Determine Complex Interplay between Genotypes and Environments." Agronomy 13, no. 2 (2023): 585. http://dx.doi.org/10.3390/agronomy13020585.

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Abiotic stress decreases crop production worldwide. In order to recommend suitable genotypes for cultivation under water deficit and heat stress conditions, an overall understanding of the genetic basis and plant responses to these stresses and their interactions with the environment is required. To achieve these goals, the multitrait genotype-ideotype distance index (MGIDI) was utilized to recognize abiotic-stress-tolerant wheat genotypes, and the weighted average of absolute scores (WAASB) index as well as the superiority index, which enables weighting between the mean performance and stabil

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T, Bayisa. "Stability Analysis of Bread Wheat Genotypes Using the AMMI Stability Model at Southeast Oromia." Food Science & Nutrition Technology 7, no. 1 (2022): 1–6. http://dx.doi.org/10.23880/fsnt-16000277.

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Ethiopia is the largest wheat producer in Sub- Saharan Africa. The productivity of wheat has increased in the last few years in the country, but low as compared to other countries. This low productivity is attributed to a number of factors including biotic, abiotic, shortage of high yielding and stable varieties. The objective of the present study is to identify high yielding and stable genotype. A total of twenty genotypes including Dambal (st. check) and Mada walabu (Local check) were evaluated for two cropping season 2017 and 2018 at four locations: Sinana, Agarfa, Goba and Gololcha. The ex

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Mahir BAŞARAN, Mehmet KARAMAN, Mustafa OKAN, Uğur BİLGE, and Doğan OKUR. "Ekmeklik Buğdayda (Triticum aestivum L.) Kalite Özellikleri İle Tane Veriminin Etkileşimi ve Uygun Genotip Seçimi." ISPEC Journal of Agricultural Sciences 4, no. 3 (2020): 609–22. http://dx.doi.org/10.46291/ispecjasvol4iss3pp609-622.

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Çalışma, yağışa dayalı ve destek sulamalı şartlarda tesadüf blokları deneme desenine göre 4 tekerrürlü olarak 2018-2019 yetiştirme sezonunda Diyarbakır’da yürütülmüştür. Amaç, kalite özellikleri ile tane verimi arasındaki etkileşimi yorumlayarak çeşit adayı olmaya uygun genotipleri belirlemek ve ıslah çalışmalarına katkı sağlamaktır. Deneme materyalini 25 genotip oluşturmuştur. Genotipler, tarımsal özellikler ve sarı pas hastalığına reaksiyonları bakımından değerlendirilmiştir. Varyans analizine göre; bin tane ağırlığı ile tane verimi, hektolitre ağırlığı ile protein oranı ve zeleny sedimantas

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Hu, Zhihang, Nan Zhang, Zhiyuan Qin, et al. "Differential Response of MYB Transcription Factor Gene Transcripts to Circadian Rhythm in Tea Plants (Camellia sinensis)." International Journal of Molecular Sciences 25, no. 1 (2024): 657. http://dx.doi.org/10.3390/ijms25010657.

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The circadian clock refers to the formation of a certain rule in the long-term evolution of an organism, which is an invisible ‘clock’ in the body of an organism. As one of the largest TF families in higher plants, the MYB transcription factor is involved in plant growth and development. MYB is also inextricably correlated with the circadian rhythm. In this study, the transcriptome data of the tea plant ‘Baiyeyihao’ were measured at a photoperiod interval of 4 h (24 h). A total of 25,306 unigenes were obtained, including 14,615 unigenes that were annotated across 20 functional categories withi

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Forouzandeh, Nahid, Sachin Srinivasan, Katia Jurdi, et al. "Digital PCR-based cell-free DNA K-Ras mutations analysis and clinical implication in pancreatic cancer." Journal of Clinical Oncology 39, no. 15_suppl (2021): e16215-e16215. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e16215.

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e16215 Background: Pancreatic cancer is one of the most fatal cancers worldwide. In addition to patients presenting later in the disease, limitations in current testing modalities pose a challenge to early diagnosis and treatment. Somatic mutations of the K-Ras gene have been suggested as a key driver of pancreatic carcinogenesis and thus proposed as a biomarker for diagnosis and therapy. Majority of these studies utilize tissue-based methods for analyzing K-Ras mutations. In recent years, liquid biopsy assay, in particular, analysis of cell-free DNA (cfDNA), has emerged as a promising noninva

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Mut, Zeki, Necibe Demirtaş, and Özge Doğanay Erbaş Köse. "Farklı Yulaf (Avena sativa L.) Genotiplerinin Destek Sulamalı ve Yağışa Dayalı Koşullarda Verim ve Bazı Fiziksel Kalite Özelliklerinin Değerlendirilmesi." Turkish Journal of Agriculture - Food Science and Technology 9, no. 1 (2021): 197–204. http://dx.doi.org/10.24925/turjaf.v9i1.197-204.3825.

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Yulaf insan yiyeceği, hayvan yemi ve tıbbi bitki olarak kullanılan önemli bir tahıldır. Bu çalışma, 22 yulaf genotipinin verim ve bazı fiziksel kalite özelliklerinin, yağışa dayalı ve destek sulamalı koşullarda incelenmesi amacıyla 2016-2017 yetiştirme sezonunda Yozgat‘ın Yerköy ilçesinde yürütülmüştür. Denemeler tesadüf blokları deneme deseninde, üç tekrarlamalı olarak kurulmuştur. Araştırmada çeşitlerin bitki boyu, salkım uzunluğu, tane verimi, biyolojik verim, bin tane ağırlığı hektolitre ağırlığı ve iç oranı değerleri incelenmiştir. Yağışa dayalı koşullarda genotiplerin bitki boyu 54,2-86,

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Nagata, Ayaka, Yuya Sekiguchi, Toru Oi, et al. "Genetic diversity of enterovirus G detected in faecal samples of wild boars in Japan: identification of novel genotypes carrying a papain-like cysteine protease sequence." Journal of General Virology 101, no. 8 (2020): 840–52. http://dx.doi.org/10.1099/jgv.0.001446.

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The genetic diversity of enterovirus G (EV-G) was investigated in the wild-boar population in Japan. EV-G-specific reverse transcription PCR demonstrated 30 (37.5 %) positives out of 80 faecal samples. Of these, viral protein 1 (VP1) fragments of 20 samples were classified into G1 (3 samples), G4 (1 sample), G6 (2 samples), G8 (4 samples), G11 (1 sample), G12 (7 samples), G14 (1 sample) and G17 (1 sample), among which 11 samples had a papain-like cysteine protease (PL-CP) sequence, believed to be the first discoveries in G1 (2 samples) or G17 (1 sample) wild-boar EV-Gs, and in G8 (2 samples) o

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Ohnami, Shumpei, Kouji Maruyama, Kai Chen, et al. "BMP4 and PHLDA1 are plausible drug-targetable candidate genes for KRAS G12A-, G12D-, and G12V-driven colorectal cancer." Molecular and Cellular Biochemistry 476, no. 9 (2021): 3469–82. http://dx.doi.org/10.1007/s11010-021-04172-8.

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AbstractDespite the frequent detection of KRAS driver mutations in patients with colorectal cancer (CRC), no effective treatments that target mutant KRAS proteins have been introduced into clinical practice. In this study, we identified potential effector molecules, based on differences in gene expression between CRC patients carrying wild-type KRAS (n = 390) and those carrying KRAS mutations in codon 12 (n = 240). CRC patients with wild-type KRAS harboring mutations in HRAS, NRAS, PIK3CA, PIK3CD, PIK3CG, RALGDS, BRAF, or ARAF were excluded from the analysis. At least 11 promising candidate mo

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Al-Ashkar, Ibrahim, Mohammed Sallam, Abdullah Ibrahim, et al. "Identification of Wheat Ideotype under Multiple Abiotic Stresses and Complex Environmental Interplays by Multivariate Analysis Techniques." Plants 12, no. 20 (2023): 3540. http://dx.doi.org/10.3390/plants12203540.

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Multiple abiotic stresses negatively impact wheat production all over the world. We need to increase productivity by 60% to provide food security to the world population of 9.6 billion by 2050; it is surely time to develop stress-tolerant genotypes with a thorough comprehension of the genetic basis and the plant’s capacity to tolerate these stresses and complex environmental reactions. To approach these goals, we used multivariate analysis techniques, the additive main effects and multiplicative interaction (AMMI) model for prediction, linear discriminant analysis (LDA) to enhance the reliabil

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AJAY, VERMA, and PRATAP SINGH GYANENDRA. "Random and Fixed Effects of Wheat Genotypes Compared by Rank Based Measures: Northern Hills Zone." INTERNATIONAL JOURNAL OF AGRICULTURE AND BIOLOGICAL SCIENCES 4, Sep & Oct 2020 (2020): 99–118. https://doi.org/10.5281/zenodo.4286944.

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<em>Rank based measures of stability based on random effects of wheat genotypes for the first year of study, Sis measures identified G11, G12, G1, G22 would be stable yield. Corrected yield measures CSis selected G12, G17, G19,G21, G22genotypes as possessing for stable yield. NPi(s) identified G4, G12, G19, G22 as desirable genotypes for this zone. Kendall ’ s coefficient of concordanceexpressed dependence among measures for ranking of wheat genotypes. Association analysis observed positive correlations of Sis, CSis & NPi(s) with other measures

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Natali, Luiz Henrique, Taciane Stein da Silva, Adriano Policam Ciena, et al. "Efeitos da corrida em esteira em músculos sóleos de ratos encurtados por imobilização." Revista Brasileira de Medicina do Esporte 14, no. 6 (2008): 490–93. http://dx.doi.org/10.1590/s1517-86922008000600003.

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O objetivo deste trabalho foi verificar as adaptações de peso e comprimento do músculo sóleo de ratos Wistar machos, além da estimativa do total de sarcômeros em série e comprimento médio dos sarcômeros, quando submetidos a um processo de remobilização em esteira. Foram utilizados 18 ratos (Wistar), divididos em três grupos: GC - músculo sóleo esquerdo (MSE) imobilizado e remobilizado solto; G10 - MSE imobilizado e remobilizado em velocidade de 10m/min; e G12 (n = 6) - MSE imobilizado e remobilizado em velocidade de 12m/min. Os resultados mostraram as seguintes variações, peso muscular: GC -22

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Chandramohan, Y., L. Krishna, B. Srinivas, et al. "Stability analysis of short duration rice genotypes in Telangana using AMMI and GGE Bi-plot models." Environment Conservation Journal 24, no. 1 (2023): 243–52. http://dx.doi.org/10.36953/ecj.11952311.

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In order to identify stable short duration rice genotypes across different agro-climatic zones in Telangana state, Additive Main Effects and Multiplicative Interaction Models (AMMI) and GGE Bi-plot analyses was performed. Analysis of variance clearly revealed that genotypes contributed highest (34.57 %) followed by environments (32.31 %) and genotype environment interaction (17.10 %) in total sum of squares indicating very greater role played by genotypes, environments and their interactions in realizing final grain yield. AMMI analysis revealed that rice genotypes viz., KNM 2305 (G12), KNM 23

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Raja, Zubair Ali, William J. Procasky, and Renee Oyotode-Adebile. "The Relative Role of Sovereign CDS and Bond Markets in Efficiently Pricing Emerging Market Sovereign Credit Risk." Journal of Emerging Market Finance 19, no. 3 (2020): 296–325. http://dx.doi.org/10.1177/0972652720932772.

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Extant literature reports mixed findings on the relative efficiency of credit default swaps (CDS) and bond markets in pricing emerging market sovereign credit risk. Using a more comprehensive data set than analyzed earlier, we reexamine this issue and find that CDS dominate bonds in the price discovery of this risk, an advantage we attribute to the greater relative liquidity of that market. One exception is during the financial crisis, suggesting that when panic hits, sovereign markets price credit risk differently. However, even then, the CDS market has a greater impact on price discovery tha

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Gvaldin, Dmitry Yu, Oleg I. Kit, Ekaterina P. Omelchuk, et al. "Frequency of somatic mutations in the KRAS gene in patients of the South Russia diagnosed with colorectal cancer." Journal of Clinical Oncology 37, no. 15_suppl (2019): e15081-e15081. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e15081.

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e15081 Background: Colorectal cancer (CRC) is a common pathology in the world; the annual incidence rate reaches 1 million cases, and the annual mortality rate exceeds 500,000. The target therapy of EGFR with monoclonal drugs improves the survival of patients with this pathology. However, the effectiveness of therapy depends on the presence of mutations in genes involved in the EGFR signaling cascade, in particular KRAS. The purpose of this study was to determine the frequency of somatic mutations in the KRAS gene in tumor samples of patients from the South Russia diagnosed with colorectal can

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Verma, Ajay, Ravish Chatrath, and Indu Sharma. "AMMI and GGE biplots for G×E analysis of wheat genotypes under rain fed conditions in central zone of India." Journal of Applied and Natural Science 7, no. 2 (2015): 656–61. http://dx.doi.org/10.31018/jans.v7i2.662.

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The highly significant environments, genotypes and G×E interaction observed by AMMI analysis of 17 wheat genotypes evaluated at 8 locations in the central zone of the country. Environments(E), genotypes -environment interaction(GE) and genotypes explained 68.8%, 17.6% and 3.2% of the total sum of squares respectively. First four interaction principal components accounted 33.7%, 30.2%, 14.6% and 12.6% of the G×E interaction variation, respectively. The highest positive IPCA1 score of genotype G8 followed by G11 and G10 supported by yield higher than the grand mean 21.8q/ha. Environments E4 (Jab

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Koffi, Eric-BZ, SDM Yao, RS Sie, et al. "Morphological Diversity among 18 Genitors of Vanuatu Tall (VTT) Coconut (Cocos nucifera L.) Population used in Crosses for Hybrids Resistant to Lethal Yellowing Disease Selection at Port-Bouët, Côte d'Ivoire." Greener Journal of Agricultural Sciences 6, no. 4 (2016): 134–44. https://doi.org/10.15580/GJAS.2016.4.020416032.

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Genetic control by creation of the coconut varieties expressing both Lethal Yellowing (LY) disease resistance and good agronomic performances led breeders to select in Tall populations which contain large diversity, some peculiar palms used as genitors. Thus, 18 genotypes of Vanuatu Tall (VTT) coded from G1 to G18 were described from 30 quantitative descriptors assessed on the coconut organs that are stem, leaf, inflorescence and fruit. The results showed that these 18 VTT genotypes were divided into two agro-morphological clusters: (i) genotypes providing large nuts with heavy components

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Michaelidou, Kleita, Chara Koutoulaki, Konstantinos Mavridis, et al. "Detection of KRAS G12/G13 Mutations in Cell Free-DNA by Droplet Digital PCR, Offers Prognostic Information for Patients with Advanced Non-Small Cell Lung Cancer." Cells 9, no. 11 (2020): 2514. http://dx.doi.org/10.3390/cells9112514.

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KRAS mutations are found in approximately one third of non-small cell lung cancer (NSCLC) patients. In this study, we aim to investigate whether KRAS G12/G13 mutant allele fraction (MAF) in cell-free DNA (cfDNA) can provide meaningful prognostic information in NSCLC. Multiplex droplet-digital PCR was used to quantitatively assess KRAS G12/G13 MAF in cfDNA from 114 pre-treated advanced disease NSCLC patients. In 14 patients, changes in KRAS G12/G13 MAF were longitudinally monitored during treatment. Plasma KRAS G12/G13 status was associated with poor patients’ outcome in terms of progression-fr

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Ghorbanian, Hamid, Mohsen Janmohammadi, Asghar Ebadi-Segherloo, and Naser Sabaghnia. "Genotypic response of barley to exogenous application of nanoparticles under water stress condition." Annales Universitatis Mariae Curie-Sklodowska, sectio C – Biologia 72, no. 2 (2019): 15. http://dx.doi.org/10.17951/c.2017.72.2.15-27.

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<p>Beneficial nanoparticles (SiO2 and TiO2) can have various profound effects on the crop physiological, biochemical and morphological characteristics. Here, we evaluated the mitigation of drought stress in barley genotypes by foliar application of SiO2 and TiO2 nanoparticles under filed condition in North West of Iran. Nanoparticles were foliar applied in late vegetative phase and during reproductive stages. Drought was imposed at by irrigation withdrawals during the dry months in the end of the growing season. We measured parameters related morphological growth, yield, and yield compon

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Klages, Birgit, Ursula Brandt, Melvin I. Simon, Günter Schultz, and Stefan Offermanns. "Activation of G12/G13 Results in Shape Change and Rho/Rho-Kinase–mediated Myosin Light Chain Phosphorylation in Mouse Platelets." Journal of Cell Biology 144, no. 4 (1999): 745–54. http://dx.doi.org/10.1083/jcb.144.4.745.

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Platelets respond to various stimuli with rapid changes in shape followed by aggregation and secretion of their granule contents. Platelets lacking the α-subunit of the heterotrimeric G protein Gq do not aggregate and degranulate but still undergo shape change after activation through thromboxane-A2 (TXA2) or thrombin receptors. In contrast to thrombin, the TXA2 mimetic U46619 led to the selective activation of G12 and G13 in Gαq-deficient platelets indicating that these G proteins mediate TXA2 receptor-induced shape change. TXA2 receptor-mediated activation of G12/G13 resulted in tyrosine pho

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Korhonen, Hanna, Beate Fisslthaler, Alexandra Moers, et al. "Anaphylactic shock depends on endothelial Gq/G11." Journal of Experimental Medicine 206, no. 2 (2009): 411–20. http://dx.doi.org/10.1084/jem.20082150.

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Anaphylactic shock is a severe allergic reaction involving multiple organs including the bronchial and cardiovascular system. Most anaphylactic mediators, like platelet-activating factor (PAF), histamine, and others, act through G protein–coupled receptors, which are linked to the heterotrimeric G proteins Gq/G11, G12/G13, and Gi. The role of downstream signaling pathways activated by anaphylactic mediators in defined organs during anaphylactic reactions is largely unknown. Using genetic mouse models that allow for the conditional abrogation of Gq/G11- and G12/G13-mediated signaling pathways b

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