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Journal articles on the topic 'GMDCT'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Hu, Wei, Zhi-Yong Zhong, Yu-Ting Gao, Xue-Feng Ren, Hai-Yang Liu, and Xiao-Jiang Tang. "Establishment of LC-MS/MS Method for Determination of GMDTC in Rat Plasma and Its Application in Preclinical Pharmacokinetics." Molecules 28, no. 3 (2023): 1191. http://dx.doi.org/10.3390/molecules28031191.

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Sodium (S)-2-(dithiocarboxylato((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)amino)-4(methylthio)butanoate (GMDTC) is the first compound to use cadmium repellent as an indication. In this paper, we established and validated a bioanalytical method for the determination of GMDTC in rat plasma, and used it to determine the drug concentrations in the plasma of rats after intravenous dosing in different genders and dosages. After pretreating the plasma samples with an acetonitrile–water–ammonia solution (70:30:1.25, v/v/v), liquid chromatographic separations were efficiently achieved with a XBridge C1

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Tang, Xiaojiang, Bo Xiao, Qile Zhao, Wei Hu, Amber McKenery, and Zhiyong Zhong. "Renal glucose transporters play a role in removal of cadmium from kidney cells mediated by GMDTC – A novel metal chelator." Human & Experimental Toxicology 42 (June 9, 2023): 096032712311830. http://dx.doi.org/10.1177/09603271231183056.

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Cadmium (Cd) is a toxic heavy metal, exposure to which leads to adverse health effects including chronic kidney damage. Tremendous efforts have been explored in identifying safe chelating agents for removing accumulated Cd from kidney, but with limited success owing to their associated side effects and the ineffectiveness in eliminating Cd. A newly developed chelating agent, sodium (S)-2-(dithiocarboxylato((2S,3 R,4R,5 R)-2,3,4,5,6-pentahydroxyhexyl) amino)-4(methylthio)butanoate (GMDTC), has been shown to effectively mobilize Cd from kidney. However, the mechanism(s) of removal are unclear, w

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Deng, Kai, Siyuan Wei, Shiyan Pang, Huiwei Jiang, and Bo Su. "Synthesizing Remote Sensing Images from Land Cover Annotations via Graph Prior Masked Diffusion." Remote Sensing 17, no. 13 (2025): 2254. https://doi.org/10.3390/rs17132254.

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Semantic image synthesis (SIS) in remote sensing aims to generate high-fidelity satellite imagery from land use/land cover (LULC) labels, supporting applications such as map updating, data augmentation, and environmental monitoring. However, the existing methods typically focus on pixel-level semantic-to-image translation, neglecting the spatial and semantic relationships among land cover objects, which hinders accurate scene structure modeling. To address this challenge, we propose GMDiT, an enhanced conditional diffusion model that extends the masked DiT architecture with graph-prior modelin

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Choi, Youn I., Jun-won Chung, Kyoung Oh Kim, et al. "Concordance Rate between Clinicians and Watson for Oncology among Patients with Advanced Gastric Cancer: Early, Real-World Experience in Korea." Canadian Journal of Gastroenterology and Hepatology 2019 (February 3, 2019): 1–6. http://dx.doi.org/10.1155/2019/8072928.

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Backgrounds/Aims. Watson for Oncology (WFO) is a cognitive technology that processes medical information by analyzing the latest evidence and guidelines. However, studies of the concordance rate between WFO and clinicians for advanced gastric cancer (AGC) are lacking.Methods. We retrospectively reviewed 65 patients with AGC who consulted WFO and the Gachon Gil Medical Center multidisciplinary team (GMDT) in 2016 and 2017. The recommendations of WFO were compared with the opinions of the GMDT. WFO provided three treatment options: recommended (first treatment option), for consideration (second

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Lisziewicz, Julianna, Dmitry I. Gabrilovich, Georg Varga, et al. "Induction of Potent Human Immunodeficiency Virus Type 1-Specific T-Cell-Restricted Immunity by Genetically Modified Dendritic Cells." Journal of Virology 75, no. 16 (2001): 7621–28. http://dx.doi.org/10.1128/jvi.75.16.7621-7628.2001.

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ABSTRACT A novel technology combining replication- and integration-defective human immunodeficiency virus type 1 (HIV-1) vectors with genetically modified dendritic cells was developed in order to induce T-cell immunity. We introduced the vector into dendritic cells as a plasmid DNA using polyethylenimine as the gene delivery system, thereby circumventing the problem of obtaining viral vector expression in the absence of integration. Genetically modified dendritic cells (GMDC) presented viral epitopes efficiently, secreted interleukin 12, and primed both CD4+ and CD8+ HIV-specific T cells capa

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Murakumo, Y., H. Ide, H. Itoh, et al. "Cloning of the cDNA encoding mast cell tryptase of Mongolian gerbil, Meriones unguiculatus, and its preferential expression in the intestinal mucosa." Biochemical Journal 309, no. 3 (1995): 921–26. http://dx.doi.org/10.1042/bj3090921.

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By using the combination of reverse-transcription PCR and rapid amplification of cDNA ends methods, a cDNA encoding mast cell tryptase was successfully cloned from the small intestine of Mongolian gerbil, Meriones unguiculatus, infected with Nippostrongylus brasiliensis. The cDNA was 1219 bp long including 810 bp of an open reading frame. Based on the deduced amino acid sequences of known mast cell tryptases of other species, the gerbil mast cell tryptase (gMCT) was highly similar to mouse mast cell protease (mMCP)-7, and seems to be translated as a prepro-enzyme with 25 amino acids of signal

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Taee, Lena, Kobra Kazemiyan Moghadam, Maryam Gholamzadeh jofreh, and Masoud Shahbazi. "Comparing the Effectiveness of Gottman Method Couple Therapy and Integrative Behavioral Couple Therapy on the Emotional Abuse of Women with Addicted Husbands." International Journal of Body, Mind and Culture 12, no. 1 (2025): 59–69. https://doi.org/10.61838/ijbmc.v12i1.707.

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Objective: The present research was conducted to compare the effectiveness of Gottman method couple therapy (GMCT) and integrative behavioral couple therapy (IBCT) on the emotional abuse of women with addicted husbands. Methods and Materials: The statistical population included all women with addicted husbands referring to the Welfare Organization in Ahvaz in 2022. In a quasi-experimental design with a pretest-posttest design with a control group, 45 people meeting the inclusion criteria were selected using purposeful sampling and randomly assigned to two experimental groups and a control grou

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Patel, Bhargav C., Devyani R. Tipre, and Shailesh R. Dave. "Biphasic Leaching Operation for the GMDC Polymetallic Bulk Concentrate." Advanced Materials Research 828 (November 2013): 117–21. http://dx.doi.org/10.4028/www.scientific.net/amr.828.117.

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A biphasic leaching operation was employed for the extraction of copper and zinc from the GMDC polymetallic bulk concentrate (PBC). Biogenerated ferric was used in cyclic manner for fed batch metal extractions from the PBC for four cycles under the pre-optimized conditions. Zn extraction was gradually decreased with each succeeding fed-batch cycle and it resulted in 67.89, 62.46, 47.37 and 14.74% of Zn extraction in 1st, 2nd, 3rd and 4th cycle respectively. In case of copper the extraction pattern was 86.63, 81.98, 75.58 and 46.51% Cu extraction in 1st, 2nd, 3rd and 4th cycle respectively. The

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Ullmann, R. Thomas, and G. Matthias Ullmann. "GMCT : A Monte Carlo simulation package for macromolecular receptors." Journal of Computational Chemistry 33, no. 8 (2012): 887–900. http://dx.doi.org/10.1002/jcc.22919.

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Rezaali, Mostafa, Reza Fouladi-Fard, and Abdolreza Karimi. "Performance of TANN, NARX, and GMDHT Models for Urban Water Demand Forecasting: A Case Study in a Residential Complex in Qom, Iran." Avicenna Journal of Environmental Health Engineering 10, no. 2 (2023): 85–97. http://dx.doi.org/10.34172/ajehe.5283.

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To keep the balance between demand and supply, methods based on the average per capita consumption were usually applied to predict water demand. More complicated models such as linear regression and time series models were developed for this purpose. However, after the introduction of artificial neural networks (ANNs), different applications of this method were used in the field of water supply management, especially for urban water demand prediction. In this study, multiple types of ANNs were studied to understand their suitability for a residential complex water demand prediction in the city

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11

Ge, Yichen, Nina Zheng, Xushen Chen, et al. "GMDTC Chelating Agent Attenuates Cisplatin-Induced Systemic Toxicity without Affecting Antitumor Efficacy." Chemical Research in Toxicology 32, no. 8 (2019): 1572–82. http://dx.doi.org/10.1021/acs.chemrestox.9b00097.

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12

Willmann, Matthew R., Nathan D. Berkowitz, and Brian D. Gregory. "Improved genome-wide mapping of uncapped and cleaved transcripts in eukaryotes—GMUCT 2.0." Methods 67, no. 1 (2014): 64–73. http://dx.doi.org/10.1016/j.ymeth.2013.07.003.

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Tang, Xiaojiang, Jinqiu Zhu, Zhiyong Zhong, et al. "Mobilization and removing of cadmium from kidney by GMDTC utilizing renal glucose reabsorption pathway." Toxicology and Applied Pharmacology 305 (August 2016): 143–52. http://dx.doi.org/10.1016/j.taap.2016.06.001.

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14

Dodda, Sundararaju, Venkata Krishnaraju Alluri, Trimurtulu Golakoti, and Krishanu Sengupta. "Acute, Subacute, and Genotoxicity Assessments of a Proprietary Blend of Garcinia mangostana Fruit Rind and Cinnamomum tamala Leaf Extracts (CinDura®)." Journal of Toxicology 2020 (July 30, 2020): 1–15. http://dx.doi.org/10.1155/2020/1435891.

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The present communication describes a battery of toxicity studies that include an acute oral toxicity, a subacute twenty-eight-day repeated oral dose toxicity, and genotoxicity studies on a herbal formulation CinDura® (GMCT). This proprietary herbal composition contains the extracts of the Garcinia mangostana fruit rind (GM) and the Cinnamomum tamala leaf (CT). The toxicological evaluations were performed following the Organization for Economic Cooperation and Development (OECD) guidelines. The acute oral toxicity study in Wistar rats suggests that the median lethal dose of CinDura® is at leas

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Kast, Richard E., Alex Alfieri, Hazem I. Assi, et al. "MDACT: A New Principle of Adjunctive Cancer Treatment Using Combinations of Multiple Repurposed Drugs, with an Example Regimen." Cancers 14, no. 10 (2022): 2563. http://dx.doi.org/10.3390/cancers14102563.

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In part one of this two-part paper, we present eight principles that we believe must be considered for more effective treatment of the currently incurable cancers. These are addressed by multidrug adjunctive cancer treatment (MDACT), which uses multiple repurposed non-oncology drugs, not primarily to kill malignant cells, but rather to reduce the malignant cells’ growth drives. Previous multidrug regimens have used MDACT principles, e.g., the CUSP9v3 glioblastoma treatment. MDACT is an amalgam of (1) the principle that to be effective in stopping a chain of events leading to an undesired outco

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Powell, Steven Francis, Elie G. Dib, Jonathan Scott Bleeker, et al. "Optimizing Genotype Matched Clinical Trial (GMCT) accrual in a community oncology program (COP)." Journal of Clinical Oncology 34, no. 15_suppl (2016): e18036-e18036. http://dx.doi.org/10.1200/jco.2016.34.15_suppl.e18036.

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Muniz, Carolina Amália de Souza Dantas, Roberto Carvalheiro, Luiz Alberto Fries, and Sandra Aidar de Queiroz. "Dois critérios de seleção na pré- desmama em bovinos da raça Gir. 2. Efeito na classificação dos animais." Revista Brasileira de Zootecnia 34, no. 3 (2005): 816–26. http://dx.doi.org/10.1590/s1516-35982005000300013.

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A utilização de dois critérios de seleção na pré-desmama, ganho médio diário do nascimento à desmama (GMD) e dias para ganhar 160 kg do nascimento à desmama (D160), foi estudada, analisando-se informações de 16.592 animais, provenientes do controle de desenvolvimento ponderal da Associação Brasileira dos Criadores de Zebu, nascidos no período de 1978 a 1994. Foram incluídos no modelo o efeito fixo de grupo de contemporâneos e os efeitos aleatórios genético aditivo de animal e materno, de ambiente permanente materno e o erro. A covariância entre os efeitos direto e materno foi considerada igual

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18

Axelrod, Charles David. "Reflections on the Fear of Death." OMEGA - Journal of Death and Dying 17, no. 1 (1987): 51–64. http://dx.doi.org/10.2190/hdrr-f2yj-wt21-gmct.

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In contemporary thanatological writing, we often encounter the injunction to “practice death,” an idea based on the assumption that by reflecting on mortality one can overcome a fear of it. The same idea appears explicitly and implicitly in numerous ancient philosophical and religious texts, such as the Bardo Thodol (known to the English community as The Tibetan Book of the Dead), Plato's Phaedo, the writings of Epicurus, and certain segments of the Old Testament. This article explores the prescription to practice death in these sources in an effort to locate its inherent rationality.

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B Soni, Hiren, V. Vijay Kumar, and Pankaj N. Joshi. "ENVIRONMENTAL IMPACT ASSESSMENT (EIA) AND ENVIRONMENTAL MANAGEMENT PLAN (EMP): A CASE STUDY OF KACHCHH, GUJARAT, INDIA." Current World Environment 14, no. 1 (2019): 99–127. http://dx.doi.org/10.12944/cwe.14.1.10.

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This case study outlines some noteworthy features of the process of Environmental Impact Assessment (EIA) and Environmental Management Plant (EMP) of Deendyal (Kandla) Port Trust (DPT) and Gujarat Mineral Development Corporation (GMDC) lignite mines, Kachchh, Gujarat, India. These key viewpoints incorporate task depiction, options, checking, portrayal of the earth, open cooperation, biophysical impacts, social effects, sway essentialness, total impacts evaluation, observing, and introduction, which are earmarked in annexure in the form of sectors requiring EIA, Ecologically Sensitive Areas (ES

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Yamano, Tomoyoshi, Sho Watanabe, Hiroyuki Hasegawa, et al. "Ex vivo–expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin grafts." Blood 117, no. 9 (2011): 2640–48. http://dx.doi.org/10.1182/blood-2010-07-293860.

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Abstract Dendritic cells (DCs) are known to regulate immune responses by inducing both central and peripheral tolerance. DCs play a vital role in negative selection of developing thymocytes by deleting T cells with high-affinity for self-peptide–major histocompatibility complexes. In the periphery, DCs mediate peripheral tolerance by promoting regulatory T-cell development, induction of T-cell unresponsiveness, and deletion of activated T cells. We studied whether allogeneic DCs, obtained from bone marrow cultured with either Flt3L (FLDCs) or granulocyte-macrophage colony-stimulating factor (G

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Yamano, Tomoyoshi, Masafumi Goto, Ryo Abe, and Hidehiro Kishimoto. "central tolerance induction by adoptive transfer of donor dendritic cells (145.5)." Journal of Immunology 184, no. 1_Supplement (2010): 145.5. http://dx.doi.org/10.4049/jimmunol.184.supp.145.5.

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Abstract The principal function of DCs is to promote T cell activation and differentiation into effecter T cells by presenting foreign Ags and providing costimulatory signals. DCs also play a critical role in maintaining not only peripheral but also central tolerance. Central tolerance is established by negative selection of developing T cells that have high-affinity TCRs for self-peptide-MHC complexes expressing on DCs or mTECs. We studied whether i.v. injection of allogeneic DCs that are obtained BM culture with Flt3L (FLDCs), GM-CSF(GMDCs) or allogeneic B cells could home to the recipient t

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Hu, Wei, Zhi-Yong Zhong, Xue-Feng Ren, Hai-Yang Liu, and Xiao-Jiang Tang. "The in vitro metabolism of GMDTC in liver microsomes of human, monkey, dog, rat and mouse: Metabolic stability assessment, metabolite identification and interspecies comparison." Journal of Pharmaceutical and Biomedical Analysis 236 (November 2023): 115718. http://dx.doi.org/10.1016/j.jpba.2023.115718.

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Kishimoto, Hidehiro, Tomoyoshi Yamano, Toshihiro Suzuki, and Ryo Abe. "Ex-vivo expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin allografts (169.12)." Journal of Immunology 186, no. 1_Supplement (2011): 169.12. http://dx.doi.org/10.4049/jimmunol.186.supp.169.12.

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Abstract The principal function of Dendritic cells (DCs) is to promote T cell activation and differentiation into effecter T cells by presenting foreign Ags and providing costimulatory signals. Also DCs are known to regulate immune responses by inducing both central and peripheral tolerance. DCs play a vital role in negative selection of developing thymocytes by deleting T cells with high-affinity for self-peptide-MHC complexes. In the periphery, DCs mediate peripheral tolerance by promoting regulatory T cell development, induction of T cell unresponsiveness, and deletion of activated T cells.

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Cadarette, S., M. Arregui Rementeria, E. Gomez Espinosa, et al. "PCR239 Quality of Life (QOL) Instruments Used in Clinicaltrials.gov-Indexed Trials of Gene-Modified Cell Therapy (GMCT) in Patients With Multiple Myeloma (MM)." Value in Health 26, no. 12 (2023): S495. http://dx.doi.org/10.1016/j.jval.2023.09.2676.

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J., Kishore Lal, Vinu C. V., Abdul Rasheed M. H., and Sony P. S. "Comparison of troponin 1 level among the patients who underwent coronary artery bypass grafting with and without adenosine as an adjunct to blood cardioplegia." International Surgery Journal 8, no. 10 (2021): 3069. http://dx.doi.org/10.18203/2349-2902.isj20213997.

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Background: Cellular injury is not avoidable with current cardioplegic solutions. No method of cardioplegia has been shown to completely protect the myocardium against cellular injury. The objective of the study is to evaluate the safety and efficacy of adenosine as an adjunct to blood cardioplegia during CABG.Methods: A retrospective study at GMCT, Thiruvananthapuram in CABG patients for 3 years from January 1, 2016, to December 31, 2019, between the age of 40 and 70 years. Patients with other chronic diseases and pre-operative echo showing EF less than 40% were excluded. The study variables

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Arya, Arun. "Isolation of AM Fungi from Rhizospheric Soil and Assessing Their Potential in Revegetating the Mining Wasteland of Gujarat using Inoculated Trees Saplings." INTERNATIONAL JOURNAL OF PLANT AND ENVIRONMENT 8, no. 03 (2023): 24–30. http://dx.doi.org/10.18811/ijpen.v8i03.03.

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Fluorspar (CaF2), is a common mineral, occurring in green, purple, yellow, or colorless crystals, which is used in metallurgy and makinga variety of chemicals used in refrigeration. Kadipani in Gujarat has large deposits of this ore. Open cast mining by GMDC has resultedin disturbed ecology. Earlier the efforts have been made by the forest department to grow tree species, in order to restore the forestecosystem, but the plants grew slowly and with stunted morphology and scanty survival. The obligate fungal symbionts known asarbuscular mycorrhizal fungi (AMF) present in plants play a key factor

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Long, Juan, Fanfang Zeng, Lili Wang, and Honglei Zhao. "Association between Education Attainment and Guideline-Directed Medication Therapy in Patients with Heart Failure and Reduced Ejection Fraction." Journal of Clinical Medicine 11, no. 14 (2022): 4235. http://dx.doi.org/10.3390/jcm11144235.

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Objective: The aim of the current study was to evaluate association of education attainment and guideline-directed medications therapy (GDMT) in patients with heart failure and reduced ejection fraction (HFrEF). Method: HFrEF patients were enrolled, and baseline characteristics were recorded. Based on highest educational attainment, patients were divided into low and high education attainment groups. Data on GDMT use at admission, discharge and follow-up were collected and between-group differences were evaluated. Results: A total of 336 patients were recruited, and 59.8% (n = 201) were define

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Umar Farooq, Fariha Ambreen, Tayyaba Khan, Amna Riaz, Syeda Zobia Fatima, and Sundas Sattar. "EFFECTIVENESS OF SENSORY INTEGRATION THERAPY AND GROSS MOTOR THERAPY FOR IMPROVING GROSS MOTOR SKILLS IN CHILDREN WITH AUTISM SPECTRUM DISORDER." Insights-Journal of Health and Rehabilitation 3, no. 2 (Health & Rehab) (2025): 646–52. https://doi.org/10.71000/jw5vpa52.

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Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental condition often associated with sensory processing difficulties and gross motor delays, both of which impact daily functioning, independence, and social participation. Impairments in balance, postural control, and coordination are frequently observed in affected children. Sensory Integration Therapy (SIT), aimed at enhancing sensory modulation and motor planning, may improve outcomes when combined with Gross Motor Therapy (GMT), a structured physical intervention targeting motor function. Objective: To evaluate the effectivenes

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Jorge Júnior, João, Vera Lucia Cardoso, and Lucia Galvão de Albuquerque. "Objetivos de seleção e valores econômicos em sistemas de produção de gado de corte no Brasil." Revista Brasileira de Zootecnia 36, no. 5 suppl (2007): 1549–58. http://dx.doi.org/10.1590/s1516-35982007000700013.

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A importância econômica de possíveis características biológicas a serem incluídas em objetivos de seleção para diferentes sistemas de produção de bovinos da raça Nelore, mediante o cálculo dos seus valores econômicos foi avaliada nesta pesquisa. Com base em informações de desempenho e parâmetros biológicos e econômicos, foram simulados diferentes sistemas de produção (ciclos de cria e completo) para dois rebanhos. O rebanho 1, com ciclo de cria (Ccr), ciclo completo (Cco) e ciclo completo com venda de reprodutores (CcoR), é um rebanho elite no qual é desenvolvido um programa seleção. Parte des

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Ali, Nasir, Rehan Masroor, Muhammad Afsheen Iqbal, Syed Muzaffar Hasan Kirmani, Hannah Khurshid, and Muhammad Adnan Akram. "Five Year Experience of Mitral Valve Repair Surgery at Armed Force Institute of Cardiology." Pakistan Armed Forces Medical Journal 72, SUPPL-3 (2022): S556–60. http://dx.doi.org/10.51253/pafmj.v72isuppl-3.9552.

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Objective: Experience of the conventional and a de novo Mitral repair techniques for the treatment of Severe Mitral Regurgitation (MR) in a Tertiary Care Cardiac Hospital of Pakistan. Study Design: Descriptive cross sectional Place and Duration of Study: Cardiac Surgical Division, Armed Forces Institute of Cardiology and National Institute of Heart Diseases, Rawalpindi, Pakistan Methodology: This was a cross sectional study conducted over a period of 5 years from 2016 to 2020, which included SeventyFive (n=75) patients in the trial, 55 females and 20 males. The mean age was 2

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Kampling, Hanna, Oskar Mittag, Stephan Herpertz, Harald Baumeister, Bernd Kulzer, and Frank Petrak. "Can trajectories of glycemic control be predicted by depression, anxiety, or diabetes-related distress in a prospective cohort of adults with newly diagnosed type 1 diabetes? Results of a five-year follow-up from the German multicenter diabetes cohort study (GMDC-Study)." Diabetes Research and Clinical Practice 141 (July 2018): 106–17. http://dx.doi.org/10.1016/j.diabres.2018.04.017.

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Bahi, brahim, hassane Ibn Elhaj El, and Aboutajdine Driss. "Optimal and Generalized Multiple Descriptions Image Coding Transform in the Wavelet Domain." April 22, 2009. https://doi.org/10.5281/zenodo.1071374.

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In this paper we propose a Multiple Description Image Coding(MDIC) scheme to generate two compressed and balanced rates descriptions in the wavelet domain (Daubechies biorthogonal (9, 7) wavelet) using pairwise correlating transform optimal and application method for Generalized Multiple Description Coding (GMDC) to image coding in the wavelet domain. The GMDC produces statistically correlated streams such that lost streams can be estimated from the received data. Our performance test shown that the proposed method gives more improvement and good quality of the reconstructed image when the wav

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Ferris, Stephen T., Ray A. Ohara, Feiya Ou, et al. "cDC1 vaccines drive tumor rejection by direct presentation independently of host cDC1." Cancer Immunology Research, May 27, 2022. http://dx.doi.org/10.1158/2326-6066.cir-21-0865.

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Abstract As a cell-based cancer vaccine, dendritic cells (DCs), derived from peripheral blood monocytes or bone marrow (BM) treated with GM-CSF (GMDCs), were initially thought to induce antitumor immunity by presenting tumor antigens directly to host T cells. Subsequent work revealed that GMDCs do not directly prime tumor specific T cells, but must transfer their antigens to host DCs. This reduces their advantage over strictly antigen-based strategies proposed as cancer vaccines. Type 1 conventional DCs (cDC1s) have been reported to be superior to GMDCs as a cancer vaccine, but whether they ac

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Ambalaparambil, Anagha, Prasanna Venkadesa Perumal, Debasis Gochhait, and Neelaiah Siddaraju. "Validation of a novel alcohol‐free preservative solution in comparison with conventional prefixation on quality of serous body fluid smears." Diagnostic Cytopathology, June 19, 2024. http://dx.doi.org/10.1002/dc.25369.

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AbstractBackgroundWe describe a novel alcohol‐free preservative composed of glucose, mannitol, disodium hydrogen orthophosphate, thymol, and distilled water (glucose‐mannitol–disodium dihydrogen orhtophosphate‐thymol [GMDT] preservative) in appropriate proportion as an alternative to alcohol prefixation (APF) of body fluids.ObjectivesTo assess the cytomorphologic preservation and staining quality of serous body fluid smears generated by GMDT preservative and compare it with smears processed by standard 50% APF.MethodologyThe study comprised 151 effusion samples. Each sample was equally divided

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Irvine, Taylor J., Paul R. Peluso, Kyle Benson, et al. "A Pilot Study Examining the Effectiveness of Gottman Method Couples Therapy Over Treatment-as-Usual Approaches for Treating Couples Dealing with Infidelity." Family Journal, October 30, 2023. http://dx.doi.org/10.1177/10664807231210123.

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The present randomized control trial examined the effectiveness of Gottman Method Couples Therapy (GMCT) over treatment-as-usual (TAU) approaches for couples presenting for therapy following the discovery of infidelity. Forty-nine couples participated in this trial and were randomized to either a GMCT or TAU control group, with 19 completing all pre- and post-treatment assessments. Results showed that GMCT was globally more effective in facilitating affair recovery than TAU approaches, notably in the areas of trust, conflict management, relational satisfaction, and quality of sex. In this arti

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Ciarella, Simone, Chengjie Luo, Vincent E. Debets, and Liesbeth M. C. Janssen. "Multi-component generalized mode-coupling theory: predicting dynamics from structure in glassy mixtures." European Physical Journal E 44, no. 7 (2021). http://dx.doi.org/10.1140/epje/s10189-021-00095-w.

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Abstract The emergence of glassy dynamics and the glass transition in dense disordered systems is still not fully understood theoretically. Mode-coupling theory (MCT) has shown to be effective in describing some of the non-trivial features of glass formation, but it cannot explain the full glassy phenomenology due to the strong approximations on which it is based. Generalized mode-coupling theory (GMCT) is a hierarchical extension of the theory, which is able to outclass MCT by carefully describing the dynamics of higher-order correlations in its generalized framework. Unfortunately, the theor

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Đức Thành, Đậu, та Nguyễn Hồng Hà. "ĐẶC ĐIỂM LÂM SÀNG, XQUANG GÃY PHỨC HỢP GÒ MÁ CUNG TIẾP TẠI BỆNH VIỆN HỮU NGHỊ VIỆT ĐỨC NĂM 2021 – 2022". Tạp chí Y học Việt Nam 518, № 1 (2022). http://dx.doi.org/10.51298/vmj.v518i1.3303.

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Mục tiêu: Mô tả đặc điểm lâm sàng, xquang của bệnh nhân gãy phức hợp gò má cung tiếp (GMCT) được điều trị tại khoa Phẫu thuật hàm mặt – Tạo hình – Thẩm mỹ, bệnh viện Hữu nghị Việt Đức năm 2021 – 2022. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang trên 305 bệnh nhân được chẩn đoán và điều trị gãy phức hợp GMCT tại khoa Phẫu thuật hàm mặt – Tạo hình – Thẩm mỹ, bệnh viện Việt Đức từ tháng 1/2021 đến tháng 3/2022. Đối tượng nghiên cứu được khai thác tiền sử, khám lâm sàng, chụp xquang để ghi nhận các chỉ số nghiên cứu. Kết quả: Đối tượng nghiên cứu có tuổi trung bình 30,5 ± 11,6 tuổi, tỷ lệ

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Borowska, Dominika, Samantha Sives, Lonneke Vervelde, and Kate M. Sutton. "Chicken CSF2 and IL-4-, and CSF2-dependent bone marrow cultures differentiate into macrophages over time." Frontiers in Immunology 13 (December 21, 2022). http://dx.doi.org/10.3389/fimmu.2022.1064084.

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Chicken bone marrow-derived macrophages (BMMΦ) and dendritic cells (BMDC) are utilized as models to study the mononuclear phagocytic system (MPS). A widely used method to generate macrophages and DC in vitro is to culture bone marrow cells in the presence of colony-stimulating factor-1 (CSF1) to differentiate BMMΦ and granulocyte-macrophage-CSF (GM-CSF, CSF2) and interleukin-4 (IL-4) to differentiate BMDC, while CSF2 alone can lead to the development of granulocyte-macrophage-CSF-derived DC (GMDC). However, in chickens, the MPS cell lineages and their functions represented by these cultures ar

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De Ré, Daniela, Pedro Henrique Lazarin Da Silva, Graziela Rayciki Behne, Mariana Paula Vazatta, and Alberito Rodrigo De Carvalho. "Verificação do efeito imediato da manipulação espinal sobre o limiar de dor à pressão em sujeitos assintomáticos." Fisioterapia Brasil 13, no. 3 (2016). http://dx.doi.org/10.33233/fb.v13i3.537.

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A manipulação espinal é um tratamento manual utilizado, principalmente, para tratar problemas osteomusculares. Pesquisas relacionam esta técnica a inúmeros benefícios, incluindo alívio da dor. O presente estudo verificou o efeito imediato da manipulação da terceira vértebra cervical e da décima segunda vértebra torácica, aplicadas isoladamente e em conjunto, sobre o limiar de dor à pressão em sujeitos assintomáticos e, ainda, comparou as técnicas empregadas. Sessenta universitários foram divididos nos grupos: simulacro (GS), manipulação cervical (GMC), manipulação torácica (GMT) e manipulação

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Scheer, Maximilian, Bruno Griesler, Elisabeth Ottlik, et al. "Variability in the distance from the end of the gray matter to the end of the conus medullaris: a case-triggered histological investigation." Journal of Neurosurgery: Spine, August 2021, 1–8. http://dx.doi.org/10.3171/2020.12.spine201890.

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OBJECTIVE The background for this investigation was the dramatic course of a 14-year-old girl with a spontaneous hemorrhage in the area of the conus medullaris resulting in a complete cross-sectional syndrome with bladder and bowel dysfunction. Despite immediate surgical treatment, the patient showed close to no postoperative improvement. Subsequent histopathological examination of the removed masses revealed a cavernoma. To better understand the link between the site and symptoms of conus medullaris lesions, the authors performed a literature search and then histological examination of the co

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Johnson, V. J., F. P. Post, J. K. Kupusovic, et al. "Impact of optimal medical therapy on left ventricular ejection fraction recovery and the occurrence of arrhythmia in patients with HFrEF fitted with the wearable cardioverter defibrillator." Europace 27, Supplement_1 (2025). https://doi.org/10.1093/europace/euaf085.765.

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Abstract Background Patients with heart failure (HF) and severely reduced left ventricular ejection fraction (LVEF) ≤ 35% (HFrEF) are at elevated risk for arrhythmias and sudden cardiac death. To evaluate potential recovery in LVEF under optimal guideline-directed medical therapy (GMDT) after initial diagnosis, patients can be provided with a wearable cardioverter-defibrillator (WCD) within the first 3 months to bridge this time. According to the ESC-HF guideline (HF-GL) introduced in 2021 GMDT consists of the "fantastic four" including Sodium-Glucose-linked-transporter-2 inhibitors (SGLT-2i).

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"Preface." IOP Conference Series: Materials Science and Engineering 1229, no. 1 (2022): 011001. http://dx.doi.org/10.1088/1757-899x/1229/1/011001.

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It is a great privilege for us to present the proceedings of ICECon2021, The International Conference on Civil Engineering and Construction Technology 2021 held in Kota Kinabalu, Sabah, Malaysia, from the 14th to 15th of December 2021. The Civil Engineering in Faculty of Engineering, Universiti Malaysia Sabah, organized this Conference; collaborated with the Institution of Engineers (IEM) Sabah, The Association of Consulting Engineers (ACEM) Sabah Chapter, and Green Materials and Advanced Construction Technology Research Unit (GMACT), Universiti Malaysia Sabah. With the theme “Emerging Technol

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Ibrahim, Michel, Linda Ruppert, Jamael Hoosain, Val Rakita, and Eman Hamad. "Abstract 255: Implementation Of An Electronic Health Record (ehr) Tool To Improve Care Delivery In The Management Of Heart Failure." Circulation: Cardiovascular Quality and Outcomes 15, Suppl_1 (2022). http://dx.doi.org/10.1161/circoutcomes.15.suppl_1.255.

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Background: The usage of guideline-directed medical therapy (GDMT) in the treatment of heart failure (HF) has shown to reduce mortality and hospitalization. However, majority of the HF patients do not receive GDMT or do not achieve the target dose despite the abondance of positive evidence. We conducted a quality improvement project at our hospital with the aim to evaluate the impact of utilization of an Epic-based EHR tool that allows adherence with evidence-based guidelines and improve efficiency in coordination of care. Methods: Our cohorts included adult patients admitted with Acute Decomp

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Li, Yong-Fang, Miao Zhao, Menglei Wang, et al. "An improved method of constructing degradome library suitable for sequencing using Illumina platform." Plant Methods 15, no. 1 (2019). http://dx.doi.org/10.1186/s13007-019-0524-7.

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Abstract Background Post-transcriptional gene regulation is one of the critical layers of overall gene expression programs and microRNAs (miRNAs) play an indispensable role in this process by guiding cleavage on the messenger RNA targets. The transcriptome-wide cleavages on the target transcripts can be identified by analyzing the degradome or PARE or GMUCT libraries. However, high-throughput sequencing of PARE or degradome libraries using Illumina platform, a widely used platform, is not so straightforward. Moreover, the currently used degradome or PARE methods utilize MmeI restriction site i

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Hu, Jian, Xinhua Jiang, Julin Gao, and Xiaofang Yu. "LFMNet: a lightweight model for identifying leaf diseases of maize with high similarity." Frontiers in Plant Science 15 (April 23, 2024). http://dx.doi.org/10.3389/fpls.2024.1368697.

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Maize leaf diseases significantly impact yield and quality. However, recognizing these diseases from images taken in natural environments is challenging due to complex backgrounds and high similarity of disease spots between classes.This study proposes a lightweight multi-level attention fusion network (LFMNet) which can identify maize leaf diseases with high similarity in natural environment. The main components of LFMNet are PMFFM and MAttion blocks, with three key improvements relative to existing essential blocks. First, it improves the adaptability to the change of maize leaf disease scal

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Canonico, Mario Enrico, Judith A. Hsia, Christopher P. Cannon, and Marc P. Bonaca. "Abstract 10477: Newer Guideline-Directed Medical Therapies Are Underutilized in 2021-22 in Patients With Heart Failure Without Diabetes." Circulation 146, Suppl_1 (2022). http://dx.doi.org/10.1161/circ.146.suppl_1.10477.

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Introduction: In 2021-22, Heart Failure (HF) guidelines endorsed quadruple therapy with beta blockers (BB),angiotensin-converting inhibitors/angiotensin receptor blockers (ACEi/ARB) or angiotensin receptor-neprilysin inhibitors (ARNI), mineral receptor antagonists (MRA) and sodium-glucose cotransporter-2 inhibitors (SGLT2i) as first-line medications to improve clinical outcomes. AHA 2022 HF guidelines specifically recommended SGLT2i even in patients without diabetes mellitus (DM) irrespective of left ventricular ejection fraction (HF). Hypothesis and Methods: Our analysis evaluated the hypothe

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Văn Anh, Phan, Nguyễn Hồng Hà та Lê Văn Nam. "ĐẶC ĐIỂM TỔN THƯƠNG TRÊN CẮT LỚP VI TÍNH Ở BỆNH NHÂN GÃY MŨI SÀNG Ổ MẮT TẠI BỆNH VIỆN HỮU NGHỊ VIỆT ĐỨC". Tạp chí Y học Việt Nam 507, № 1 (2021). http://dx.doi.org/10.51298/vmj.v507i1.1343.

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Mục tiêu: Nghiên cứu này được thực hiện nhằm mô tả các đặc điểm tổn thương trên CLVT của nhóm bệnh nhân được điều trị tại Khoa Phẫu thuật Hàm mặt-Tạo hình- Thẩm mỹ, Bệnh viện Hữu nghị Việt Đức. Qua đó, góp phần hỗ trợ các bác sĩ trong việc chẩn đoán và lên kế hoạch điều trị cho những bệnh nhân gãy MSOM. Đối tượng và phương pháp: Nghiên cứu mô tả chùm ca bệnh dựa trên phim CLVT ở 43 bệnh nhân gãy MSOM được điều trị từ thàng 01/2020 đến tháng 04/2021 tại Khoa Hàm mặt- Tạo hình- Thẩm mỹ, Bệnh viện Hữu nghị Việt Đức. Dùng phần mềm SPSS để phân tích số liệu thống kê. Kết quả: Trong số 43 bệnh nhân,

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Zeng, Tiwei, Chengming Li, Bin Zhang, et al. "Rubber Leaf Disease Recognition Based on Improved Deep Convolutional Neural Networks With a Cross-Scale Attention Mechanism." Frontiers in Plant Science 13 (February 28, 2022). http://dx.doi.org/10.3389/fpls.2022.829479.

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Natural rubber is an essential raw material for industrial products and plays an important role in social development. A variety of diseases can affect the growth of rubber trees, reducing the production and quality of natural rubber. Therefore, it is of great significance to automatically identify rubber leaf disease. However, in practice, different diseases have complex morphological characteristics of spots and symptoms at different stages and scales, and there are subtle interclass differences and large intraclass variation between the symptoms of diseases. To tackle these challenges, a gr

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Carassia, C., M. Mennuni, A. Degiovanni, S. De Vecchi, R. Erbetta, and G. Patti. "P219 IS DISPROPORTIONALITY ENOUGH TO IDENTIFY CANDIDATES FOR PERCUTANEOUS MITRAL VALVE REPAIR? A CLINICAL CASE." European Heart Journal Supplements 24, Supplement_C (2022). http://dx.doi.org/10.1093/eurheartj/suac012.211.

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Abstract Functional mitral regurgitation (FMR) is defined as regurgitation with structurally normal leaflets secondary to the distortion of the LV in the context of dilated cardiopathy. The conflicting results emerged from the MITRA–FR and COAPT trials have raised a new interest in the individuation of “primary–like” components of MR. In this scenario, a binary classification in proportionate and disproportionate FMR has been proposed by Garland et al. When the MR is completely due to LV remodeling, they observed a linear relationship between ERO and LVEDV, defining a proportionate FMR; on the

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Mont, L., J. Daubert, V. Kutyifa, et al. "Has the use of concomitant cardiac medications improved over time in primary prevention ICD patients? Insights from the APPRAISE ATP study." European Heart Journal 44, Supplement_2 (2023). http://dx.doi.org/10.1093/eurheartj/ehad655.344.

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Abstract Introduction Patients (pts) implanted with an ICD for a primary prevention (PP) typically receive concomitant medications (meds) to treat LV dysfunction. However, It is not well established whether compliance with guideline-directed medical therapy (GDMT) has improved over time in this population. Methods Data were drawn from the MADIT-RIT (2009-2012) and APPRAISE ATP (2016-present) studies. Both studies were global in scope and enrolled pts who were implanted with an ICD for PP indications. Meds prescribed at baseline were compared between the two studies. Meds of interest included:

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