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Dissertations / Theses on the topic 'Male breast cancer'

Author: Grafiati

Published: 4 June 2021

Last updated: 17 June 2025

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1

Opara, Esther. "Predictors of Mastectomy in Male Breast Cancer." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3956.

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Male breast cancer (MBC) is rare, and research on the predictors of MBC has been limited because of inadequate funding in and outside of the United States. One goal of this study was to eradicate the stereotyping of breast cancer as a female disease. The emergence of medical technology and education to benefit the public will help to ensure greater health awareness at the individual, community, and global levels. The purpose of this study was to understand the influence of the predictors of age; race (Black, White, and Other); and grade of cancer (I, II, or III) on the outcome of mastectomy in

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2

Sundara, Rajan Sreekumar. "Investigating male breast cancer using transcriptomics and immunohistochemistry." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/15847/.

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Background: The rare nature of male breast cancer (MBC) has led to its management being guided by the extensive research conducted in the field of female breast cancer (FBC). The aim of this study was to evaluate MBC at both protein and molecular level to improve understanding of its pathology. Methodology: Immunohistochemistry analysis was performed in MBC (n=428) TMAs for 18 biomarkers (ERα, ERβ1, ERβ2, ERβ5, Total PR, AR, CK5/6, CK14, CK18, CK19, p53, Bcl-2, Her2, E-cadherin, Ki67, Survivin, Prolactin and FOXA1). The manual scoring of ERα and Ki67 was correlated with a fully automated immun

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3

Nilsson, Cecilia. "Characterization of Male Breast Cancer : From Molecule to Clinical Outcome." Doctoral thesis, Uppsala universitet, Centrum för klinisk forskning, Västerås, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-172670.

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The aim of this thesis was to investigate different aspects of male breast cancer (MBC), and to compare these with findings in female breast cancer (FBC). In paper I, a population–based study was performed to investigate possible differences in treatment and outcome between MBC and FBC patients. MBC and FBC presented with a similar distribution of stage. Although no differences in primary treatment strategy were demonstrated, MBC patients had significantly poorer overall and relative survival, indicating a more aggressive disease. Paper II aimed to assess the value of clinicopathological facto

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4

Rosenblatt, Adena. "Regulation of Steroid Receptor Activity in the Breast and Urogenital Tract." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_dissertations/274.

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Steroid receptors are important in the pathogenesis of a variety of disease states and modulate cellular processes through differential gene expression. Therefore, understanding the regulation of steroid receptors is essential. Environmental sodium arsenite, a toxin associated with male infertility, and arsenic trioxide, a possible prostate cancer therapeutic agent, are inorganic trivalent semimetals. The mechanism of arsenic action in male urogenital tract tissues is not clear. Since androgen receptor (AR) plays an important role in spermatogenesis and prostate cancer, we explored the possibi

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5

Thomas, Sarah Rose. "The experiences of male partners of women with breast cancer : an interpretative phenomenological analysis." Thesis, University of Leicester, 2017. http://hdl.handle.net/2381/40494.

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Breast cancer is the most common cancer diagnosis in the UK, with most cases being diagnosed in females. With advances in treatment, it is being increasingly recognised as a chronic condition, which has an impact not only on the patient, but also on the patient’s family. Research suggests that partners often become the primary caregivers for these women, and yet there has been very little research exploring the impact of this diagnosis on partners. The literature review aimed to explore the information needs of male partners of women with breast cancer. Following a systematic literature search

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6

Brock-Midding, Evamarie [Verfasser]. "Influencing Factors of Health Inequity among Male Breast Cancer Patients in Germany / Evamarie Brock-Midding." Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1228979006/34.

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7

Coltri, Julia Anne. "Transgender male patients and hereditary breast cancer risk: broaching difficult topics to reduce healthcare disparities." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555683611281611.

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8

Chilcott-Burns, Sarah. "Association of single nucleotide polymorphisms in FGFR2 with male breast cancer, following modified DNA extraction methodology." Thesis, University of Portsmouth, 2014. https://researchportal.port.ac.uk/portal/en/theses/association-of-single-nucleotide-polymorphisms-in-fgfr2-with-male-breast-cancer-following-modified-dna-extraction-methodology(25ace0dd-234b-4e30-94e6-834f81ca5198).html.

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The Breakthrough Generations Study and Laboratory was set up in 2007 to study the epigenetics of breast cancer in women and men in the United Kingdom over a potential forty year prospective period from 2006 to 2046. The remit was to collect blood samples, lifestyle and medical information from volunteers and then to compare the genetic analysis of the samples to the data collected to look for trends and patterns. The blood samples were stored in a relatively unique format, being in 500 μl buffy coat samples in micro-capillary tubes and at the time of writing 4 million aliquots were in storage.

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9

Thellenberg, Karlsson Camilla. "Prostate cancer : epidemiological studies of risk factors." Doctoral thesis, Umeå universitet, Institutionen för strålningsvetenskaper, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1862.

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In spite of the fact that prostate cancer is the most common male cancer in both Sweden and many other countries in the developed world, little is known of risk factors and predisposing conditions. The only well recognized risk factors are age, race and familial aggregation. More knowledge about risk factors could lead to better preventive measures together with better treatments. One way to evaluate this is to study second primary cancers; the connection between two different cancers can give valuable insight in etiology or clues to shared risk factors. This thesis aims at evaluating risk fac

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10

Holmén, Linnea, and Kjellson Sara. "Att vara man fast i en kvinnas sjukdom : Att vara man fast i en kvinnas sjukdom." Thesis, Högskolan i Halmstad, Akademin för hälsa och välfärd, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-30929.

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Bröstcancer är en sjukdom som främst drabbar kvinnor, därför kan många män uppleva att det finns begränsat med information som riktar sig till dem. Under en 10 - års period, 2005-2014, var det i Halland endast sju män som diagnostiserades med bröstcancer och år 2014 insjuknade totalt 61 män i Sverige. Att män sällan insjuknar i bröstcancer kan vara en av orsakerna till att många män inte är medvetna om att de kan drabbas. Att vara man och drabbas av bröstcancer kan innebära att inte bara den fysiska bilden av en individ förändras utan även den psykiska världen, det är därför viktigt att få rät

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11

Burton, LizaJoy. "Snail-Cathepsin L Signaling in Human Breast and Prostate Cancers." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 2017. http://digitalcommons.auctr.edu/cauetds/60.

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Prostate and breast cancer are the leading causes of cancer-related death in men and women, respectively, and metastasis is the primary factor underlying the high mortality rates.1 Snail transcription factor is an important molecule that drives prostate and breast cancer metastasis through the process of epithelial mesenchymal transition (EMT). Proteolytic enzymes that promote invasion and metastasis such as the lysosomal cysteine protease cathepsin L (Cat L) have been shown to degrade E-cadherin, promoting the epithelial mesenchymal transition (EMT).2 It has also been shown that silencing Cat

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12

Norström, Adina, and Karin Simon. "Det kan väl inte hända en man? : En litteraturöversikt om mäns upplevelser av att leva med bröstcancer." Thesis, Ersta Sköndal högskola, Institutionen för vårdvetenskap, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:esh:diva-4355.

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Bakgrund: Bröstcancer hos män är en ovanlig, ouppmärksammad sjukdom. Mindre än en procent av alla som får bröstcancer är män. Detta gör att männen som drabbas av denna sjukdom inte bara går igenom de motgångar som en cancersjukdom innebär utan även vad det kan innebära att drabbas av en sjukdom som vanligen drabbar kvinnor. Syfte: Att beskriva mäns upplevelse av att leva med bröstcancer. Metod: En litteraturöversikt då nio stycken vetenskapliga originalstudier granskades. Dessa hade kvalitativ, kvantitativ eller mixad metod och hämtades från Cinahl och referenslistor från andra vetenskapliga a

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13

Loaring, Jessica M. "How do women with breast cancer and their male partners experience and understand sexual intimacy and body image following surgery and reconstruction?" Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3894/.

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The following work has been completed as part of the Birmingham University Clinical Psychology doctorate. Volume I contains a literature review and research paper. The literature review summarises research exploring intimate partner or wider social support on medication adherence for people living with HIV. The research paper describes a qualitative study into the body image and sexual intimacy experiences of women who have undergone a mastectomy with reconstruction and their partners. Volume II of the thesis contains four clinical practice reports (CPRs) and the abstract of a fifth which was

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14

Pogson, Delia. "How individuals who may have concerns about a family history of breast cancer make sense of genetic information." Thesis, University of Southampton, 2013. https://eprints.soton.ac.uk/359001/.

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An individual’s personal experience may lead them to start to think about their own family history, to wonder if they might have inherited a genetic risk of breast cancer and start to consider the scientific genetic information. The focus for this research is how individuals make sense of genetic information and has been undertaken with members of the general population before they come into contact with specialist services. There are clear limitations in the literature addressing the focus of this research, including the population sampled - individuals before they come into contact with serv

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15

Sighoko, Mawadzoue Frida Dominique. "Cancers du sein (féminin) et du foie en Afrique de l’Ouest : évolution temporelle de l’incidence et évaluation des facteurs de risque en Gambie et au Mali." Thesis, Lyon 1, 2011. http://www.theses.fr/2011LYO10297/document.

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En Afrique subsaharienne, le fardeau exact du cancer reste largement méconnu et sous étudié. La Gambie et le Mali sont parmi les rares pays d'Afrique à avoir des registres de cancer opérationnels basés sur la population. Les données allant de 1988 à 2006 pour la Gambie et de 1987 à 2009 pour Bamako-Mali, ont été utilisées afin d'analyser les taux d'incidence en fonction de l'âge, du sexe, de l'ethnicité et de caractériser les profils des femmes atteintes de cancers du sein et du foie. Les données ont été arbitrairement divisées en deux sous périodes ; 1988-1997 et 1998-2006 pour la Gambie et 1

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16

Kaloianova, Maria Simeonova. "Imaging features of male breast cancer in a South African population." Thesis, 2017. https://hdl.handle.net/10539/24861.

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A research report submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, in partial fulfilment of the requirements for the degree of Master of Medicine in Diagnostic Radiology Johannesburg, 2017.<br>INTRODUCTION: Male breast cancer is a very rare entity, representing less than 1% of all cancers affecting men (1, 2). Only 0.7% of all breast carcinomas are attributed to male breast cancer (3). As a result, there is little published data worldwide and especially from South Africa about the imaging features of breast malignancy in men. This study looked at the

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17

Abreu, António Miguel Henriques da Cunha. "Male breast cancer: prognostic and predictive factors of response to therapy." Doctoral thesis, 2016. https://repositorio-aberto.up.pt/handle/10216/99525.

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18

Abreu, António Miguel Henriques da Cunha. "Male breast cancer: prognostic and predictive factors of response to therapy." Tese, 2016. https://repositorio-aberto.up.pt/handle/10216/99525.

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19

Smither-Williams, Vickie J. Franzini Luisa Rosenau Pauline Vaillancourt. "The effect of African Americans' ethnographic paradigms and cultural explanatory model of breast cancer in framing the male partner's attitudes and behaviors about the woman's breast cancer diagnosis." 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1450530.

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20

Barros, Sónia Macedo. "HER2 Status in Male Breast Cancer: a comparison between protein expression by immunohistochemistry and gene amplification by fluorescence in situ hybridization." Master's thesis, 2020. https://hdl.handle.net/10216/131214.

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21

Barros, Sónia Macedo. "HER2 Status in Male Breast Cancer: a comparison between protein expression by immunohistochemistry and gene amplification by fluorescence in situ hybridization." Dissertação, 2020. https://hdl.handle.net/10216/131214.

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22

Lai, Tzu-Chia, and 賴姿嘉. "Part I：Proteomic analysis of potential breast cancer markers by two-dimensional differential gel electrophoresis Part II：Proteome differences between male and female fetal cells in amniotic fluid." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/29426837075686411309.

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碩士<br>國立清華大學<br>生物資訊與結構生物研究所<br>98<br>在哺乳動物中，性別的發展是由基因和荷爾蒙所調控，始於受精卵的染色體結構（XY或XX）。接著由Y染色體上的SRY基因的表現而促使性腺的發育，形成男性的睪丸。本實驗利用蛋白質體學為基礎的方法，包括二維差異電泳和MALDI-TOF MS，分析羊水中的男性和女性胎兒細胞之間表現差異的蛋白質。在三次獨立二維差異電泳分析後，共有46個蛋白質點表現量有差異，分別屬30個不同的蛋白質，其中有7個蛋白質（annexin A1, cathepsin D, cytoskeletal 19, protein disulfide-isomerase A3, F-actin-capping protein subunit beta, Rho GDP-dissociation inhibitor 1 and vimentin）在三次獨立實驗的其中兩次實驗當中都顯示為表現差異1.5倍以上，其中一些蛋白質使用西方墨點法做再次的驗證。本實驗所鑑定的差異表現蛋白質可能可以做為男女性鑑別的生物標誌分子，在懷孕早期從母親陰道分泌物中偵測。此外，本研究方法所建立的實驗平台可以提供往後尋找與染色體異常的胎兒相關的生物標誌分子。

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23

Malek, Daniela [Verfasser]. "Interaction of estrogen receptors and the TGF-β [TGF-beta] signal transduction pathway : impact on migration of human breast cancer cells / vorgelegt von Daniela Malek". 2007. http://d-nb.info/984089748/34.

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