Academic literature on the topic 'Medication-induced Falls'

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Journal articles on the topic "Medication-induced Falls"

1

Smith, Robert G. "Fall-Contributing Adverse Effects of the Most Frequently Prescribed Drugs." Journal of the American Podiatric Medical Association 93, no. 1 (2003): 42–50. http://dx.doi.org/10.7547/87507315-93-1-42.

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The 200 most frequently prescribed medications in 2000 were reviewed for adverse effects that have the potential to cause fall injuries. The actual number of different medications reviewed was 169 after eliminating duplicates due to listing of medications by both brand and generic names. Of these 169 medications, adverse effects of documented traumatic injuries and falls were reported for 9.5% (n = 16). Four hundred forty-eight adverse effects were identified and organized into 13 broad categories representing drug-induced changes in nervous, circulatory, and muscular systems. These changes we
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2

Saedon, Nor Izzati, Goh Choon Hian, Frith James, Wan Azman Wan Adnan, and Tan Maw Pin. "27 Cerebral Autoregulation Associated with Falls in Older Persons with Orthostatic Hypotension?" Age and Ageing 48, Supplement_4 (2019): iv6—iv8. http://dx.doi.org/10.1093/ageing/afz164.27.

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Abstract Background It is considered well-established that orthostatic hypotension (OH) is associated with falls, population-based studies have found that a large proportion of community-dwelling older adults fulfill the criteria for OH without experiencing falls. It is therefore postulated that older individuals with OH may only experience fall if cerebral autoregulation, which is the mechanism by which the brain blood flow is maintained constant through a autoregulatory range, is impaired. Objective To evaluate the relationship between cerebral autoregulation and OH in older individuals with
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3

Hughes, David, Meirion Jordan, Patricia A. Logan, et al. "Looking for the “Little Things”: A Multi-Disciplinary Approach to Medicines Monitoring for Older People Using the ADRe Resource." Geriatrics 5, no. 4 (2020): 79. http://dx.doi.org/10.3390/geriatrics5040079.

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Advances in medicines have increased the effectiveness of treatments and the social and cultural authority of doctors. However, as prescribing has become the dominant modality of treatment, the “pharmaceuticalization” of medical practice has often resulted in treatment “at a distance”, with doctors having limited contact with patients. Older and poorer people, who are socially distanced from medical prescribers, suffer more adverse drug reactions (ADRs) than the general population. A team approach to checking patients systematically for ADRs, as detailed in manufacturers’ literature, can minim
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4

Vasic, Nada, Branislava Milenkovic, Dragica Pesut, Ruza Stevic, and Dragana Jovanovic. "Drug induced lung disease - amiodarone in focus." Medical review 67, no. 9-10 (2014): 334–37. http://dx.doi.org/10.2298/mpns1410334v.

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More than 380 medications are known to cause pulmonary toxicity. Selected drugs that are important causes of pulmonary toxicity fall into the following classes: cytotoxic, cardiovascular, anti-inflammatory, antimicrobial, illicit drugs, miscellaneous. The adverse reactions can involve the pulmonary parenchyma, pleura, the airways, pulmonary vascular system, and mediastinum. Drug-induced lung diseases have no pathognomonic clinical, laboratory, physical, radiographic or histological findings. A drug-induced lung disease is usually considered a diagnosis of exclusion of other diseases. The diagn
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5

Stens, Oleg, Bradley Neutel, and Elizabeth L. Goodman. "An Ounce of Prevention, a Pound of Complications: A Case of Statin-Induced Necrotizing Myopathy in a Frail Elderly Patient." Geriatrics 7, no. 2 (2022): 33. http://dx.doi.org/10.3390/geriatrics7020033.

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The use of statins for primary prevention in older adults remains controversial. In this manuscript, we present a case of an 81-year-old woman with a history of HTN, HLD, Alzheimer’s dementia and osteoporosis, who presented to a geriatrics clinic with profound muscle weakness accompanied by new functional deficits in the setting of taking double her prescribed dose of atorvastatin. She was admitted to the hospital where she was found to have rhabdomyolysis. Muscle biopsy and serologic work up revealed anti-HMG statin co-reductase myopathy as the cause of her symptoms. The patient was treated w
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6

Nayati, Jasir T., and Alan R. Hirsch. "136 CerefolinNAC Therapy-Induced Dizziness." CNS Spectrums 23, no. 1 (2018): 85–86. http://dx.doi.org/10.1017/s1092852918000329.

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AbstractStudy ObjectiveCerefolinNAC (CFLN-NAC) contains L-methylfolate (6 mg), methylcobalamin (2 mg), and N-acetylcysteine [NAC] (600 mg) [Pamlab 2017]. Dizziness and lightheadedness have not heretofore been described with use of CFLN-NAC.MethodsCase Study: A 64 year old right-handed female was started on CFLN-NAC for smell and taste issues. Over a three day period, she experienced a gradual increase in dizziness. This was a non-vertiginous lightheadedness, so severe that she was unable to walk, and would lie down the entire day to alleviate the dizziness. It was associated with nausea, but w
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7

Singh, Reetu R., Zoe McArdle, Lindsea C. Booth, et al. "Renal Denervation in Combination With Angiotensin Receptor Blockade Prolongs Blood Pressure Trough During Hemorrhage." Hypertension 79, no. 1 (2022): 261–70. http://dx.doi.org/10.1161/hypertensionaha.121.18354.

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Majority of patients with hypertension and chronic kidney disease (CKD) undergoing renal denervation (RDN) are maintained on antihypertensive medication. However, RDN may impair compensatory responses to hypotension induced by blood loss. Therefore, continuation of antihypertensive medications in denervated patients may exacerbate hypotensive episodes. This study examined whether antihypertensive medication compromised hemodynamic responses to blood loss in normotensive (control) sheep and in sheep with hypertensive CKD at 30 months after RDN (control-RDN, CKD-RDN) or sham (control-intact, CKD
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8

Russell, Joshua, Meghan J. Arwood, Nicole M. Del Toro-Pagán, et al. "Case Report: Performing a Medication Safety Review Assisted by Pharmacogenomics to Explain a Prescribing Cascade Resulting in a Patient Fall." Medicina 59, no. 1 (2023): 118. http://dx.doi.org/10.3390/medicina59010118.

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Pharmacotherapy for major depressive disorder (MDD) typically consists of trial-and-error and clinician preference approaches, where patients often fail one or more antidepressants before finding an optimal regimen. Pharmacogenomics (PGx) can assist in prescribing appropriate antidepressants, thereby reducing the time to MDD remission and occurrence of adverse drug events. Since many antidepressants are metabolized by and/or inhibit cytochrome P450 enzymes (e.g., CYP2C19 or CYP2D6), drug-induced phenoconversion is common in patients on antidepressant combinations. This condition influences the
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9

Meyer, Ashley, Andrea Ogle, Margaret Shatara, et al. "OTHR-09. The prevalence and complex management of MEK inhibitor induced cutaneous side effects." Neuro-Oncology 24, Supplement_1 (2022): i148—i149. http://dx.doi.org/10.1093/neuonc/noac079.548.

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Abstract BACKGROUND: Cutaneous side effects commonly occur with MEK inhibitor (MEKi) therapy and can be challenging to manage. METHODS: A retrospective chart review was performed on sixteen pediatric patients treated with MEKi therapy for at least three months. These patients were diagnosed with either a brain tumor, plexiform neurofibroma, Langerhans Cell Histiocytosis, or Parkes Weber Syndrome (PWS). OBJECTIVES: To describe cutaneous side effects from MEKi therapy, compare the side effect profiles of patients treated for different diagnoses, and compare the side effect profiles between diffe
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10

Ruilope, L. M., M. C. Casal, M. Praga, et al. "Additive antiproteinuric effect of converting enzyme inhibition and a low protein intake." Journal of the American Society of Nephrology 3, no. 6 (1992): 1307–11. http://dx.doi.org/10.1681/asn.v361307.

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The hypothesis that converting enzyme inhibition and a protein-restricted diet could have additive antiproteinuric effects has been tested. A group of 17 patients with proteinuria in excess of 3 g/24 h per 1.73 m2 of body surface area were submitted to a 3-wk period of study, after a 4-wk wash-out period during which protein intake was 1.0 g/kg per day and in the absence of any medication. During the first and second weeks of the study, protein intake was lowered to 0.3 g/kg per day, and in the third week, it returned to 1.0 g/kg per day. Enalapril (20 mg daily) was administered during the sec
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