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Relevant bibliographies by topics / MiR-122-5p

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Academic literature on the topic 'MiR-122-5p'

Author: Grafiati

Published: 4 June 2021

Last updated: 12 February 2022

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Journal articles on the topic "MiR-122-5p"

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Liao, Wen, Yu Ning, Hai-Jia Xu, et al. "BMSC-derived exosomes carrying microRNA-122-5p promote proliferation of osteoblasts in osteonecrosis of the femoral head." Clinical Science 133, no. 18 (2019): 1955–75. http://dx.doi.org/10.1042/cs20181064.

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Abstract Mesenchymal stem cells (MSCs) with multipotential differentiation capacity can differentiate into bone cells under specific conditions and can be used to treat osteonecrosis (ON) of the femoral head (ONFH) through cell transplantation. The current study aims to explore the role of bone marrow (BM) MSCs (BMSCs)-derived exosomes carrying microRNA-122-5p (miR-122-5p) in ONFH rabbit models. First, rabbit models with ONFH were established. ONFH-related miRNAs were screened using the Gene Expression Omnibus (GEO) database. A gain-of-function study was performed to investigate the effect of

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Meng, Lei, Zhangming Chen, Zhe Jiang, et al. "MiR-122-5p suppresses the proliferation, migration, and invasion of gastric cancer cells by targeting LYN." Acta Biochimica et Biophysica Sinica 52, no. 1 (2019): 49–57. http://dx.doi.org/10.1093/abbs/gmz141.

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Abstract Gastric cancer (GC) is one of malignant tumors with high mortality and morbidity in the world. MicroRNA-122 (miR-122) acts as a tumor suppressor in a variety of cancers and has been found to be dominant in gastric adenocarcinoma. However, the specific biological function of miR-122-5p in GC is not completely clear. In this study, we found that miR-122-5p was low-expressed in GC tissues and cell lines by using qRT-PCR. Overexpression of miR-122-5p inhibited the proliferation, migration, and invasion of GC cells by using CCK-8 and transwell assays. On the contrary, downregulation of miR

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Hukowska-Szematowicz, Beata, Agata Maciejak-Jastrzębska, Małgorzata Blatkiewicz, et al. "Changes in MicroRNA Expression during Rabbit Hemorrhagic Disease Virus (RHDV) Infection." Viruses 12, no. 9 (2020): 965. http://dx.doi.org/10.3390/v12090965.

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Current knowledge on the role of microRNAs (miRNAs) in rabbit hemorrhagic disease virus (RHDV) infection and the pathogenesis of rabbit hemorrhagic disease (RHD) is still limited. RHDV replicates in the liver, causing hepatic necrosis and liver failure. MiRNAs are a class of short RNA molecules, and their expression profiles vary over the course of diseases, both in the tissue environment and in the bloodstream. This paper evaluates the expression of miRNAs in the liver tissue (ocu-miR-122-5p, ocu-miR-155-5p, and ocu-miR-16b-5p) and serum (ocu-miR-122-5p) of rabbits experimentally infected wit

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Badacz, Rafał, Paweł Kleczyński, Jacek Legutko, et al. "Expression of miR-1-3p, miR-16-5p and miR-122-5p as Possible Risk Factors of Secondary Cardiovascular Events." Biomedicines 9, no. 8 (2021): 1055. http://dx.doi.org/10.3390/biomedicines9081055.

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Ischemic event in one arterial territory increases the risk of a subsequent ischemic event. Circulating microRNAs (miRs) emerge as a potential clinical tool to assess risk of subsequent atherothrombotic events such as cardiovascular death (CVD), myocardial infarction (MI) and ischemic stroke (IS). In this prospective study, we searched for athero-specific miRs related to cardiovascular event risk in patients with symptomatic coronary, carotid lesion, or both territories involvements. The choice of particular miRs was based on database research (Pub-Med, Bethesda, MD, USA) taking into considera

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Jiao, Yigang, Li Zhang, Jun Li, Yuqi He, Xin Zhang, and Jingzhe Li. "Exosomal miR-122-5p inhibits tumorigenicity of gastric cancer by downregulating GIT1." International Journal of Biological Markers 36, no. 1 (2021): 36–46. http://dx.doi.org/10.1177/1724600821990677.

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Background: microRNAs (miRNAs) are non-coding RNAs with important roles in the progression of human cancers, including gastric cancer. Exosomes are extracellular vesicles, which could transfer numerous noncoding RNAs, such as miRNAs. Here, in our study, we intended to investigate the role of exosomal miR-122-5p in gastric cancer progression. Methods: Exosomes were isolated utilizing commercial kit or ultracentrifugation. Biomarkers of exosomes or epithelia-mesenchymal transition (EMT) were monitored by western blot. Expression levels of miR-122-5p and G-protein-coupled receptor kinase interact

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Hänninen, Mikko, Toni Jäntti, Heli Tolppanen, et al. "Association of miR-21-5p, miR-122-5p, and miR-320a-3p with 90-Day Mortality in Cardiogenic Shock." International Journal of Molecular Sciences 21, no. 21 (2020): 7925. http://dx.doi.org/10.3390/ijms21217925.

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Cardiogenic shock (CS) is a life-threatening emergency. New biomarkers are needed in order to detect patients at greater risk of adverse outcome. Our aim was to assess the characteristics of miR-21-5p, miR-122-5p, and miR-320a-3p in CS and evaluate the value of their expression levels in risk prediction. Circulating levels of miR-21-5p, miR-122-5p, and miR-320a-3p were measured from serial plasma samples of 179 patients during the first 5–10 days after detection of CS, derived from the CardShock study. Acute coronary syndrome was the most common cause (80%) of CS. Baseline (0 h) levels of miR-

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Salazar-Ruales, Carolina, Jessica-Viviana Arguello, Andrés López-Cortés, et al. "Salivary MicroRNAs for Early Detection of Head and Neck Squamous Cell Carcinoma: A Case-Control Study in the High Altitude Mestizo Ecuadorian Population." BioMed Research International 2018 (November 21, 2018): 1–9. http://dx.doi.org/10.1155/2018/9792730.

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Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with the highest incidence worldwide. HNSCC is often diagnosed at advanced stages, incurring significant high mortality and morbidity. The use of saliva, as a noninvasive tool for the diagnosis of cancer, has recently increased. Salivary microRNAs (miRNAs) have emerged as a promising molecular tool for early diagnosis of HNSCC. The aim was to identify the differential expression of salivary miRNAs associated with HNSCC in the high altitude mestizo Ecuadorian population. Using PCR Arrays, miR-122-5p, miR-92a-3p, miR-1

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Zhi, Feng, Naiyuan Shao, Lian Xue та ін. "Characteristic MicroRNA Expression Induced by δ-Opioid Receptor Activation in the Rat Liver Under Prolonged Hypoxia". Cellular Physiology and Biochemistry 44, № 6 (2017): 2296–309. http://dx.doi.org/10.1159/000486067.

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Background/Aims: Hypoxic/ischemic injury to the liver is a frequently encountered clinical problem with limited therapeutic options. Since microRNAs (miRNAs) are involved in hypoxic/ ischemic events, and δ-opioid receptor (DOR) is protective against hypoxic/ischemic injury, we asked if pharmacological activation of DOR can alter hypoxic events by regulating miRNA expression in the liver. As the first step, the present work aimed at testing the effect of DOR activation on hepatic miRNA expression in hypoxia. Methods: Male Sprague Dawley rats were exposed to hypoxia (9.5-10% O2) for 1, 5, or 10

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Liu, Naihua, Yuancheng Huang, Fengbin Liu, and Hong Liu. "Serum exosomal miR-122-5p, GAS, and PGR in the non-invasive diagnosis of CAG." Open Medicine 16, no. 1 (2021): 1350–55. http://dx.doi.org/10.1515/med-2021-0342.

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Abstract Objective The aim of this study was to integrate the serum exosomal miRNA miR-122-5p with canonical serological biomarkers for the non-invasive screening of chronic atrophic gastritis (CAG) patients. Methods miR-122-5p and U6 were amplified by the quantitative reverse transcription polymerase chain reaction (RT-qPCR), gastrin (GAS), pepsinogen I (PG-I), and PG-II and were measured by ELISA. The area under the receiver operating characteristic (ROC) curves and their correlation were analyzed. Results In the present study, GAS level and PG-I/PG-II ratio (PGR) were increased in CAG group

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Pushkin, Anton A., Ilya A. Alliluev, Eduard E. Rostorguev, et al. "Role of miR-122-5P, miR-107, miR-22-3P, and miR-330-3P microRNAs in regulation of HIF1A expression in high-grade gliomas." Journal of Clinical Oncology 38, no. 15_suppl (2020): e14550-e14550. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e14550.

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e14550 Background: HIF1-alfa is a powerful regulator of angiogenesis and cell invasion activating a wide range of oncogenes. Control of the HIF1-alpha transcription is strictly regulated by many molecular pathways, including miRNAs which can become targets for gene therapy of cancer. Methods: The study included 30 patients with histologically verified high-grade gliomas. RNAs were isolated from 30 paired (tumor and control) samples using the TRIzol reagent (Thermo Fisher, USA). The cDNA synthesis was performed using the Reverta MMLV kit (Sintol, Russia). Expression of miRNAs and HIF1A was eval

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Dissertations / Theses on the topic "MiR-122-5p"

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Heinemann, Frauke Gudrun [Verfasser]. "miR-122-5p- und miR-206-Nachweis in Serum: Nichtinvasive prognostische Biomarker für das klarzellige Nierenzellkarzinom / Frauke Gudrun Heinemann." Bonn : Universitäts- und Landesbibliothek Bonn, 2018. http://d-nb.info/1170872492/34.

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Heinemann, Frauke [Verfasser]. "miR-122-5p- und miR-206-Nachweis in Serum: Nichtinvasive prognostische Biomarker für das klarzellige Nierenzellkarzinom / Frauke Gudrun Heinemann." Bonn : Universitäts- und Landesbibliothek Bonn, 2018. http://d-nb.info/1170872492/34.

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Koyama, Satoshi. "Dynamic changes of serum microRNA-122-5p through therapeutic courses indicates amelioration of acute liver injury accompanied by acute cardiac decompensation." Kyoto University, 2018. http://hdl.handle.net/2433/232103.

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Conference papers on the topic "MiR-122-5p"

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Bahmer, Thomas, Susanne Krauss-Etschmann, Dominik Buschmann, et al. "miR-122-5p and miR-191-5p are increased in plasma small extracellular vesicles in asthma." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa5203.

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