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Dissertations / Theses on the topic 'OncomiR (oncomiRs)'

Author: Grafiati

Published: 3 June 2025

Last updated: 1 August 2025

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1

Manaka, Maakomele R. "Oncoming traffic." Thesis, Rhodes University, 2016. http://hdl.handle.net/10962/1021220.

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The poems in my collection Oncoming Traffic mainly look at the silence in my personal conflicts. Fusing different styles and tones of writing from the lyrical to the surreal, these poems grapple with issues I struggle with on a daily basis. First as a man, second as a man with a physical disability, and lastly as a black man dealing with the reality of living in a dysfunctional/disabled society. The silence in my personal conflicts means, writing what I cannot say, stripping myself bare and vulnerable. My inspiration has come from poets who articulate such silences.

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2

Fuziwara, Cesar Seigi. "Influência do MicroRNA let-7 e miR-17-92 como oncomiRs no câncer." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/42/42134/tde-27092010-152352/.

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No câncer, alterações em microRNAs (miRNAs), pequenos RNAs que regulam a tradução protéica, exerce efeito oncogênico (oncomiR). Os oncomiRs regulam genes chave para a proliferação celular e apoptose, sendo importantes para a biologia do câncer. O carcinoma papilífero de tiróide apresenta alterações genéticas alinhadas na via MAPK (RET>RAS>BRAF>ERK). Observamos que a indução do oncogene RET/PTC diminui a expressão de let-7 em células foliculares tiroidianas. Na linhagem TPC-1 (com RET/PTC-1), a introdução de let-7 diminui a proliferação celular e a fosforilaçãode ERK, indicando papel de gene su

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3

Hoyt, Jennifer. "The Role of MicroRNA-155 and MicroRNA-146a as Putative Oncomirs in the Tumor Progression of Prostate Cancer." VCU Scholars Compass, 2008. http://scholarscompass.vcu.edu/etd/1557.

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Prostate cancer is the most common cancer occurring in males. The identification of novel microRNAs (miRs) that contribute to tumor progression represents prospective treatment targets. miRs are small non-coding RNAs important in gene regulation with specific tissue expression patterns. Each miR is thought to affect the expression of hundreds of different RNA targets. Two putative oncomiRs, miR-155 and miR-146a, were shown to be differentially expressed in the human derived, prostate cell sublines M12 and F6. Quantification of endogenous miR expression showed high levels in the metastatic

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4

Kundmüller, Caminiti Franz. "The Arbitration in Public Procurement: (Dis)trust and Aporia. Brief Comments to the oncoming regulation of the new Public Procurement Law." Derecho & Sociedad, 2015. http://repositorio.pucp.edu.pe/index/handle/123456789/118357.

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This article doesn’t pretend to be an exhaustive analysis about the proposals contended in the oncoming regulation of the new Public Procurement Peruvian Law.It begins with a reflection about the importance on trust, and it continues by analyzing inherent issues to the principles that characterize arbitration, and that, in a near future, should be used to ‘arbitralize’ arbitration on public procurement matter.<br>Este artículo no pretende un análisis exhaustivo sobre las propuestas contenidas en el futuro Reglamento de la Nueva Ley de Contrataciones del Estado.Comienza con una reflexión sobre

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5

Диброва, Михаил Александрович. "Способ многопутевой маршрутизации в компьютерных сетях большой размерности". Doctoral thesis, Киев, 2017. https://ela.kpi.ua/handle/123456789/19104.

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Багатошляхова маршрутизація характеризується великою часовою складністю пошуку множини шляхів, що не перетинаються. Часова складність знаходження найкоротшого шляху по алгоритму Дейкстри представляє собою величину O(kN2). При знаходженні k-шляхів часова складність збільшується відповідно в k раз. В зв’язку з цим, для пошуку множини шляхів, що не перетинаються, в рамках цієї роботи був запропонований модифікований метод «гілок та границь». Це досягається за рахунок виключення операцій перебору варіантів формування кожного шляху. В процесі роботи алгоритму у відповідності з методом «гілок та гра

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6

Biester, Lars. "Cooperative automation in automobiles." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät II, 2009. http://dx.doi.org/10.18452/15935.

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Das Ziel dieser Dissertation ist die systematische Entwicklung eines weiterführenden Konzeptes zur Fahrer-Fahrzeug Kooperation, dessen Tauglichkeit anhand empirischer Daten evaluiert und im Hinblick auf sein belegbares Potential in Bezug auf bestehende Ansätze bewertet werden soll.Da Annahmen und Prämissen der Mensch-Maschine-Interaktion den Ausgangspunkt bilden, beginnt die dezidierte Auseinandersetzung und begriffliche Differenzierung von Kooperation in eben diesem Kontext und führt folgerichtig zu einer definitorischen Abgrenzung gegenüber existierenden Ansätzen, der Forderung eines spezifi

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7

Vestin, Albin, and Gustav Strandberg. "Evaluation of Target Tracking Using Multiple Sensors and Non-Causal Algorithms." Thesis, Linköpings universitet, Reglerteknik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-160020.

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Today, the main research field for the automotive industry is to find solutions for active safety. In order to perceive the surrounding environment, tracking nearby traffic objects plays an important role. Validation of the tracking performance is often done in staged traffic scenarios, where additional sensors, mounted on the vehicles, are used to obtain their true positions and velocities. The difficulty of evaluating the tracking performance complicates its development. An alternative approach studied in this thesis, is to record sequences and use non-causal algorithms, such as smoothing, i

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8

Lin, Ching-Wen, and 林晴雯. "Characterization of oncomiRs in HCC: Implication of miR-122 in metastatic tumor." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/43054204784561381047.

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碩士<br>國立陽明大學<br>醫學生物技術研究所<br>94<br>MicroRNAs (miRNAs) are small hairpin, endogenous RNAs encoded in the genomes of plants, animals and virus. They are transcribed by RNA polymerase II and are processed to mature miRNAs (~22mer) by Drosha and Dicer. miRNA negatively regulates its target gene(s) by either translational repression or mRNA cleavage. Approximate 53% of miRNAs have been mapped to chromosome aberrant regions in cancers and many target genes of miRNAs belong to oncogenes or genes that affect cell growth, differentiation or apoptosis. Some of the miRNAs have been designated as oncomiRs

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9

Liao, Ya-Chun, and 廖亞純. "The anti-leukemia application of nature product HQ17(3) via regulation of oncomirs." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/21799426661760640871.

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碩士<br>國立陽明大學<br>醫學生物技術暨檢驗學系<br>101<br>Alkylene hydroquinones (AHQ) were purified from the sap of the laquer tree Rhus succedanea. According to previous research, AHQ has three major isoforms, HQ17(1), HQ17(2) and HQ17(3). HQ17(3), (10′(Z), 13′(E), 15′(E) –heptadecatrienylhydroquinone) has the strongest cytotoxic effect on cancer cells and can inhibits topoisomerase IIα activity. miRNAs are a class of small non-coding regulatory RNA molecules. miRNAs are post-transcriptional regulators, by binding to the 3’-UTR of their target mRNAs and causing translational repression or sequence-specific mRNA

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10

Cheng-FuHsu and 徐承甫. "Identify New Mutational Signature in Cancer Patients by Oncomine Panel." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/q9k44f.

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碩士<br>國立成功大學<br>資訊工程學系<br>106<br>With the invention and popularity of the next generation sequencing, more and more researches that use whole genome sequencing and whole exome sequencing for analyzing are published. However, not all people afford to the cost of whole genome sequencing and whole exome sequences. Besides, In the aspect of mutation load, Oncomine Panel can represent the whole exome sequencing to a high degree, and the genes in Oncomine Panel are druggable. Therefore, it is possible to know the important genetic mutation information of the patient with reducing the cost. This stud

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11

Hoyt, Jennifer Renee. "The role of microRNA-155 and microRNA-146a as putative oncomirs in the tumor progression of prostate cancer /." 2008. http://hdl.handle.net/10156/2239.

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12

Lee, Chia-Wen, and 李佳玟. "To screen Chinese herb medicines capable of down-regulating miR-155 expression and establish an oncomirs reporter system." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/17617493114751547986.

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碩士<br>國立陽明大學<br>醫學生物技術暨檢驗學系暨研究所<br>99<br>MicroRNAs (miRNAs) are a group of endogenous non-coding small RNAs, a length of about 19 to 24 nucleotides. They are evolutionarily conserved and function as negative regulator of gene expression. miRNAs can bind to 3’UTR of target mRNA and inhibit translation of target mRNA. miRNAs modulate cellular processes including proliferation, differentiation, apoptosis and metabolism. When the balance of cellular miRNAs is disrupted, it may cause disease including cancer. In this study, we mainly focused on miR-155. miR-155 is an oncogenic miRNA. It is overexpr

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13

Li, Jun-Bin, and 黎俊彬. "The Study on Safe Passage of Oncoming Straight and Left-Turn Vehicles." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/04049071601262866902.

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碩士<br>國立交通大學<br>運輸科技與管理學系<br>93<br>Mutual disturbances of these paths of oncoming straight and left-turn vehicles will still exist for signalized intersections that allow vehicles turning left at green signal. Because of inappropriate operation between oncoming straight and left-turn vehicles of signalized intersections of urban areas in Taiwan the department of traffic ever offered corrigible opinions involve in right of way, center of intersections adjudging hard and indirectly encouraged to accelerate left-turn vehicles. But all still lack quantification analysis. Therefore, this problem is

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14

Maher, S. G., B. A. S. Bibby, Hannah L. Moody, and G. Reid. "MicroRNAs and Cancer." 2015. http://hdl.handle.net/10454/18035.

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No<br>MicroRNAs are a relatively new class of small, noncoding RNA species that represent a cornerstone of cell biology, with diverse roles ranging from embryonic development to aging. miRNAs function to regulate posttranscriptional gene expression, are critical to the normal function of cells, and as such are frequently dysregulated during disease processes. In this chapter, we discuss the biogenesis and mechanism of action of miRNA and their role in cancer initiation, promotion, and progression. In addition, we discuss the most recently identified dual roles of miRNA in epigenetic gene regul

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15

Wang, Chao-hui, and 王昭惠. "The Influences of Different Oncoming Ball Velocity and Stimulus-response Compatibility with Return Balls on Reaction Time and Movement time for Table Tennis Players of Elementary School." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/29147928794216560922.

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碩士<br>國立屏東教育大學<br>體育學系<br>99<br>The purpose of this study was to probe the effects of different oncoming ball velocity and stimulus-response compatibility with return balls on reaction time and movement time. The participants contains 10 boys and 11 girls from Lin-Yuan Elementary school in Kaohsiung County between the ages 11.11±1.01, the heights 146.62±8.30cm, and the weights 36.98±8.83kg. They have played table tennis for about 3 years. The signals from infrared sensors, electromyographic sensors, accelerometer and acoustic sensors were acquired through NI DAQ card and analyzed by LabVIEW（50

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16

Zovoilis, Athanasios. "MicroRNA Expression Profiling of Multipotent Adult Germline Stem Cells." Doctoral thesis, 2008. http://hdl.handle.net/11858/00-1735-0000-0006-AF4D-3.

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