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Journal articles on the topic 'Periferní nerv'

Author: Grafiati
Published: 4 June 2021
Last updated: 18 February 2022

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1

Ceé, Jiří. "Peripheral nerve injury of the upper limb." Neurologie pro praxi 20, no. 4 (September 1, 2019): 267–74. http://dx.doi.org/10.36290/neu.2019.127.

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2

Ridzoň, Petr. "Electromyography, nerve conduction studies, repetitive nerve stimulation." Neurologie pro praxi 21, no. 4 (September 8, 2020): 264–67. http://dx.doi.org/10.36290/neu.2020.048.

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3

Kraus, Josef. "Traumatic lesions of peripheral nerves and brachial plexus in children." Neurologie pro praxi 20, no. 4 (September 1, 2019): 261–66. http://dx.doi.org/10.36290/neu.2019.126.

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Vujović, Rade, Irena Cvrkota, Miroslav Samardžić, Lukas Rasulić, Vladimir Baščarević, Andrija Savić, and Novak Lakićević. "Surgery of peripheral nerve injuries." Zdravstvena zastita 41, no. 6 (2012): 20–27. http://dx.doi.org/10.5937/zz1203020v.

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MEHEDINTU-IONESCU, Mihai, Ovidiu STEFANESCU, and Radu Cristian JECAN. "Nervous Regeneration Allograph Type of Periferic Nerv." Medicina Moderna - Modern Medicine 26, no. 2 (June 27, 2019): 57–60. http://dx.doi.org/10.31689/rmm.2019.26.2.57.

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Cvrkota, Irena, Miroslav Samardžić, Lukas Rasulić, Vladimir Baščarević, Mirko Mićović, Radovan Mijalčić, Mirjana Nagulić, and Igor Jovanović. "Nerve grafting after peripheral nerve injuries in children." Zdravstvena zastita 41, no. 6 (2012): 12–19. http://dx.doi.org/10.5937/zz1203012c.

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7

Ehler, Edvard, and editor hlavního tématu FEAN -. "Poranění plexu a periferních nervů." Neurologie pro praxi 20, no. 4 (September 1, 2019): 247. http://dx.doi.org/10.36290/neu.2019.124.

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Minks, Eduard, Hana Streitová, Zdeněk Mackerle, Alexandra Minksová, and Markéta Hermanová. "Ultrasound diagnosis of benign peripheral nerve tumors in upper limbs - case report of 4 patients." Neurologie pro praxi 19, no. 6 (December 10, 2018): 450–55. http://dx.doi.org/10.36290/neu.2019.022.

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9

Srećković, Svetlana. "Ultrasound and nerve stimulator guided peripheral nerve blocks of the upper and lower limbs." Serbian Journal of Anesthesia and Intensive Therapy 40, no. 1-2 (2018): 25–44. http://dx.doi.org/10.5937/sjait1802025s.

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10

Varış, Onur, Güray Togral, Murat Arıkan, and Murat Aydın. "Case Report: Malign Periferal Nerve Sheath Tumor." Acta Oncologica Turcica 49, no. 2 (2016): 131–34. http://dx.doi.org/10.5505/aot.2015.39358.

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Has Selmi, Nazan, Sukran Sahin, Alp Gurbet, Gurkan Turker, Sibel Kul, Ali Anil, and Emine Karaman. "Obturator Nerve Block in Adductor Spasticity: Comparison of Peripheral Nerve Stimulator and Ultrasonography Techniques." Turkish Journal of Anesthesia and Reanimation 41, no. 4 (October 11, 2013): 121–25. http://dx.doi.org/10.5152/tjar.2013.49.

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12

EYİGÖR, Can, Alihan PİRİM, Mehmet ARGIN, Meltem UYAR, Dündar SABAH, and Mehmet ZİLELİ. "Sciatalgia in a Patient with a Rare Peripheral Nerve Sheath Tumor: Differential Diagnosis." Turkiye Klinikleri Journal of Medical Sciences 31, no. 3 (2011): 759–62. http://dx.doi.org/10.5336/medsci.2010-17014.

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YILMAZ, Sanem, Gül SERDAROĞLU, Semra ŞEN, and Sarenur GÖKBEN. "A Neurobrucellosis Case Presenting with Bilateral Facial Nerve Palsy and Peripheral Neuropathy." Turkiye Klinikleri Journal of Pediatrics 24, no. 1 (2015): 18–21. http://dx.doi.org/10.5336/pediatr.2014-41269.

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14

KÜPELİ, İlke, Ufuk KUYRUKLUYILDIZ, Sara TAŞ, Nigar BİRCAN OCAK, and Ayşin ALAGÖL. "Comparison of the Effects of Regional Anesthesia/Peripheral Nerve Block and General Anesthesia on Preoperative Anxiety." Turkiye Klinikleri Journal of Anesthesiology Reanimation 14, no. 1 (2016): 1–6. http://dx.doi.org/10.5336/anesthe.2015-48041.

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15

İPEKDAL, HÜSEYİN İLKER. "Peripheral Nerve Lesions Secondary to Varicose Vein Surgery of the Lower Extremity: Review of the Literature." Damar Cerrahi Dergisi 21, no. 3 (2012): 276–84. http://dx.doi.org/10.9739/uvcd.2012-32117.

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16

Uhlíř, Petr, Milada Betlachová, and Petra Stará. "Cardiac function in hypertensive patients with metabolic syndrome and microalbuminuria." Medicína pro praxi 13, no. 2 (May 1, 2016): 96–98. http://dx.doi.org/10.36290/med.2016.021.

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17

Kurniawan, Leny Candra, and Ikhwan Abdullah. "PENGARUH AKUPUNKTUR JIN’S 3 NEEDLE TERHADAP PENURUNAN INTENSITAS NYERI DIABETIC NEUROPATHY PERIFER." Journal of Islamic Medicine 4, no. 1 (March 31, 2020): 46–51. http://dx.doi.org/10.18860/jim.v4i1.9051.

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Diabetic Peripheral Neuropathy is a type of nerve damagethat occurs due to diabetes. High blood sugar levels in thelong term can cause damage to nerve fibers throughout thebody, such as legs, feet, blood circulation, heart, digestivesystem, and urinary tract. Diabetic Peripheral Neuropathy isa serious complication of diabetes that often causes pain inthe limbs. Pain management Diabetic Peripheral Neuropathyis usually by administering pain medication for a long periodof time. These medicines will have side effects. The use ofacupuncture as an alternative to help reduce the intensity ofpain in peripheral diabetic neuropathy has proven to beeffective and relatively without side effects. The advantage ofacupuncture therapy is that it has relatively no side effects.The general aim of this study is to reduce the intensity of painin peripheral neuropathy. The research design usesquantitative methods. The study population was all patientswith peripheral neuropathy who visited the Harmoni HealthyClinic in March-May 2019. The sampling method used wasaccidental sampling. The benefits of this study provide analternative for DM sufferers to reduce the intensity ofneuropathic pain naturally with acupuncture without fear.side effects. From the results of this study it is known thatthere is an influence of Jin’s Three Needle acupuncture inreducing the intensity of pain in Peripheral Neuropathy.Calculations using statistical SPSS 21 with paired sample ttest obtained significant results (0.00) from the value of α(0.05), then H1 is accepted. So with a significance level of5%, it can be concluded that Jin's Three Needle acupuncturecan reduce the intensity of pain in diabetic peripheralneuropathy
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18

Putri, Rima Novia. "AKTIVITAS FISIK PADA PASIEN DIABETES MELITUS TIPE 2 DENGAN NEUROPATI PERIFER : TINJAUAN LITERATUR." Jurnal Keperawatan Abdurrab 3, no. 1 (June 13, 2019): 1–7. http://dx.doi.org/10.36341/jka.v3i1.764.

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Type 2 diabetes mellitus is a chronic disease that could cause damage to foot peripheral nerves, namely peripheral neuropathy. Diabetic peripheral neuropathy is a damage and inability to regenerate nerve cells due to exposure of chronic hyperglycemia which can lead to various symptopms and complications. Therapy is aimed at improving symptoms and delaying development of peripheral neuropathy, one of which is physical activity which is one of the cornerstones of management of diabetes mellitus. An explanation of the benefits of physical activity in diabetes mellitus has been widely discussed, but nore in peripheral neuropathy. This literature review aims to explain the types and benefits of physical activity in peripheral neuropathy. Seven literature reviewed were obtained through electronic database search EBSCOHost, Proquest, and Clinical Key with key words physical activity, exercise intervention, diabetic peripheral neuropathy, and type 2 diabetes mellitus. Peripheral neuropathy patients can carry out various types of physical activity, either weight bearing or non-weight bearing exercise. Patients with ulcers, wounds and severe foot deformity can do non-weight bearing exercise such as static cycling and upper body ergometer. Another can do walking, aerobics, balance exercises, stretching, tai chi, resistance training, and foot ankle exercises. Aerobics is a physical activity that can prevent and delay development of peripheral neuropathy. Balance training can improve sensory and motor neuropathy. In general, physical activity can improve innervation in the cutaneous tissue, regenerate nerve cells, improve the symptoms of neuropathy in the form of pain, balance disorders, risk of falls, and obstacles to physical mobility.
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ÇİFTÇİ, Fatih, and Yasemin ALTAN. "Comparing Effects of Midazolam and Dexmedetomidine Sedation on Ultrasound Guided Infraclavicular Nerve Block for Upper Extremity Orthopedic Surgeries." Turkiye Klinikleri Journal of Anesthesiology Reanimation 17, no. 1 (2019): 8–15. http://dx.doi.org/10.5336/anesthe.2019-64922.

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20

Chávez Lara, Fanny Abigail, Tayde Abigail Rosario López, Diana Vanessa Valle Bravo, Nancy Alejandra Venegas Hernández, and Luis Antonio Hernández González. "Contaminación enterobacteriana de alimentos cárnicos consumidos en la FES Iztacala y su periferia." Revista CuidArte 5, no. 9 (February 19, 2016): 6. http://dx.doi.org/10.22201/fesi.23958979e.2016.5.9.69119.

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<div>Las enfermedades transmitidas por alimentos son aquellas que se originan por la ingesti&oacute;n de alimentos contaminados en cantidades suficientes para afectar la salud. El objetivo de esta investigaci&oacute;n fue identificar enterobacterias en alimentos c&aacute;rnicos consumidos en establecimientos y puestos ambulantes cercanos a la Facultad de Estudios Superiores Iztacala (FESI). Metodolog&iacute;a: estudio tipo descriptivo, transversal y prospectivo. Se seleccionaron aleatoriamente 10 sitios con venta de alimentos. Los procedimientos microbiol&oacute;gicos estuvieron basados en las normas NOM-114- SSA1-1994, NOM-065-SSA1-1993 y NOM-092- SSA1-1994. Para la detecci&oacute;n de enterobacterias en c&aacute;rnicos, se llevaron a cabo dos fases: etapa presuntiva (pruebas bioqu&iacute;micas) y la etapa confirmativa en donde se emple&oacute; como medio de</div><div>cultivo caldo lactosado bilis verde brillante. En la prueba de mes&oacute;filos, el 90% de los cultivos fueron positivos; en coliformes obtuvimos un 42% de positividad; coliformes fecales 64%. Estos resultados indican la presencia de carga enterobacteriana en el 95% de las muestras estudiadas; el 25% pertenece al g&eacute;nero Salmonella; en tinci&oacute;n de gram, 95% fueron gramnegativas. El entorno influye directamente en la salud de las personas, ya que un inadecuado manejo en la preparaci&oacute;n de alimentos puede conducir al incremento en la prevalencia de enfermedades gastrointestinales.</div><div><br /></div>
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KART, Caner Erman, Ahmet Cemil İSBİR, Onur AVCI, İclal ÖZDEMİR KOL, Kenan KAYGUSUZ, and Sinan GÜRSOY. "The Effects of Interscalene Block Performed Alone or with Ultrasonography-Guided Peripheric Nerve Stimulator on Block Success, Hemodynamic Parameters and Perfusion Index." Turkiye Klinikleri Cardiovascular Sciences 32, no. 1 (2020): 37–44. http://dx.doi.org/10.5336/cardiosci.2019-71793.

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22

Santana, M. I., P. P. Bombonato, L. V. Araújo, A. P. F. Castello, and T. B. Escanhoela. "Irrigação do timo em aves da linhagem Paraíso Pedrês (Gallus gallus domesticus)." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 60, no. 2 (April 2008): 307–14. http://dx.doi.org/10.1590/s0102-09352008000200005.

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A vascularização arterial do timo (número, origem e ordenação) bem como a distribuição parenquimal dos ramos penetrantes foram estudadas em 40 aves da linhagem Paraíso Pedrês. Trinta aves foram injetadas com látex e dissecadas, enquanto 10 aves tiveram seus sistemas arteriais injetados com resina (metil metacrilato e mercox) para a preparação de moldes vasculares. A principal fonte de irrigação encontrada foi a associação dos ramos oriundos das artérias comuns do nervo vago, tireóideas e ingluviais, sendo que seus ramos penetravam o parênquima dos lobos, principalmente pelas suas extremidades cranial e caudal. A partir da penetração, os ramos tímicos apresentavam distribuição predominante para a periferia do lobo, formando uma trama capilar poligonal, com espaços irregulares, característica de um órgão linforreticular.
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Alves, Luciana Pires. "Diálogos extemporâneos no cotidiano escolar: a pesquisa com as crianças." ETD - Educação Temática Digital 14, no. 1 (November 18, 2010): 281. http://dx.doi.org/10.20396/etd.v14i1.1253.

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A pesquisa Injustiças Cognitivas: ressignificando os conceitos de cognição, aprendizagem e saberes no cotidiano da escola, que vimos desenvolvendo desde janeiro de 2008, na Escola Municipal Ana Nery – SME-D, de Caxias/RJ, busca investigar a produção de conhecimentos sobre a leitura e a escrita por crianças das classes populares consideradas pela escola como portadoras de “dificuldades de aprendizagem”. As crianças com as quais pesquisamos vivem na periferia da periferia: o Bairro de Jardim Gramacho – aterro sanitário situado no município de Duque de Caxias e rodeado por favelas. A maioria das famílias tem no lixão sua fonte de renda.Procuramos estudar as lógicas operatórias das crianças em suas relações cotidianas, tomando como pressuposto o postulado de Boaventura de Sousa Santos de que a injustiça social está diretamente relacionada às “injustiças cognitivas”. O uso deste conceito nos levou a pensar nas configurações da escola: até que ponto o conceito de cognição com que a escola trabalha está impregnado da dinâmica instrumental da cognição, limitando o campo de ação das práticas pedagógicas, pois desconsidera as possibilidades de invenção e de problematização? O que surge, quando procuramos fraturar o discurso das “dificuldades de aprendizagem” e como estas podem ser “lidas” na perspectiva das injustiças cognitivas? Instigadas por estas questões, buscamos investigar a formulação de novas possibilidades para a ação educativa da escola a partir da revisão-ampliação do conceito de cognição, articulando-o a uma perspectiva político-epistemológica fundada na concepção de “injustiças cognitivas”.
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Gandadikusumah, R. Dadan G., Hermawan N. Rasyid, Nucki N. Hidajat, and Yoyos D. Ismiarto. "Efektivitas Membran Amnion Liofilisasi (Handmade Tubular) sebagai Nerve Conduit pada Perbaikan Cedera Saraf Perifer Tikus dengan Gap 5 mm." Majalah Kedokteran Bandung 45, no. 3 (September 2013): 192–98. http://dx.doi.org/10.15395/mkb.v45n3.150.

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Kuswardani, Kuswardani, Zainal Abidin, Suci Amanati, and Muhammad Ma`ruf. "Pengaruh Terapi Latihan Dan Kinesio Taping Pada Lesi Nerve Peroneus E.C Kusta." Jurnal Fisioterapi dan Rehabilitasi 3, no. 1 (February 1, 2019): 100–108. http://dx.doi.org/10.33660/jfrwhs.v3i1.38.

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Lesi Nerve Peroneus e.c Kusta adalah kelumpuhan otot di anterior dan lateral pada kaki akibat kerusakan atau cidera pada saraf peroneus. Kusta adalah penyakit menular kronis yangdisebabkan oleh Mycobacterium leprae. Penyakit ini menyerang kulit, saraf perifer, mukosa saluran pernapasan bagian atas, dan mata. Kusta dapat disembuhkan dan pengobatan pada tahap awal dapat mencegah kecacatan. Permasalahan yang timbul pada pasien Lesi Nerve Peroneus e.c Kusta ini adalah kelemahan pada extremitas bawah yang menyebabkan penurunan sifat fisiologis otot, keterbatasan lingkup gerak sendi, penurunan kekuatan otot dan atrofi otot. Terapi yang diberikan pada kasus ini dengan menggunakan terapi latihan gerak aktif-asisted, pasif dan stretching untuk menjaga lingkup gerak sendi dan menjaga sifat fisiologis otot, Kinesio taping diberikan untuk support muscle. Tujuan : Mengetahui pengaruh terapi latihan dan kinesio taping pada kasus lesi nerve peroneus dalam meningkatkan kekuatan otot dan peningkatan kemampuan fungsional kaki. Hasil : Setelah dilakukan terapi selama enam kali, hasilnya adalah peningkatan nilai kekuatan otot p value (Asymp. Sig 2 tailed) sebesar 0,002 yang berarti dibawah nilai kritis < 0,005 bermakna bahwa terjadi peningkatan kekuatan otot yang signifikan, sedangkan untuk kemampuan fungsional kaki tidak menunjukkan perubahan yang signifikan hal ini ditunjukkan dengan p value sig (2-tailed) sebesar 0,899 yang berarti tidak ada perbedaan yang signifikan antara sebelum dan sesudah terapi. Kesimpulan : berdasarkan penelitian ini menunjukkan bahwaterapi latihan dan penggunaan kinesiotaping dapat meningkatkan kekuatan otot tetapi tidak dapat meningkatkan kemampuan fungsional kaki secara signifikan.
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Saquet, Marcos Aurelio. "UMA GEOGRAFIA (I)MATERIAL VOLTADA PARA A PRÁXIS TERRITORIAL POPULAR E DESCOLONIAL / A (im)material Geography focused on popular and decolonial territorial praxis / Una geografía (in)material centrada en la praxis territorial popular y decolonial." REVISTA NERA, no. 57 (April 27, 2021): 54–78. http://dx.doi.org/10.47946/rnera.v0i57.8497.

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Neste texto, que resulta das nossas inquietações, pesquisas e colaborações dentro e fora da universidade, ilustramos importantes aspectos da nossa práxis territorial popular e descolonial, por meio de alguns dos resultados do nosso trabalho de pesquisa e cooperação realizado com camponeses de diferentes municípios do Sudoeste do Paraná (sujeitos individuais e/ou associados) e com cidadãos da periferia da cidade de Francisco Beltrão, trabalhando em equipes interdisciplinares e interinstitucionais e, especialmente, com os sujeitos “estudados” em cada projeto. Nós optamos por uma abordagem territorial e popular de pesquisa e de trabalho solidário, centrado na participação social, no diálogo e na integração de conhecimentos acadêmicos e populares, práxis que efetivamos em três projetos nos quais experimentamos alguns processos de desenvolvimento territorial, no campo e na cidade, numa perspectiva contra-hegemônica e descolonial.Como citar este artigo: SAQUET, Marcos. Uma Geografia (i)material voltada para a práxis territorial popular e descolonial. Revista NERA, v. 24, n. 57, p. 54-78, Dossiê I ELAMSS, 2021.
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KOŞUCU, Müge, Hülya ULUSOY, Nesrin ERCİYES, Murat TOPBAŞ, and Ahmet U. TURHAN. "The Effects of Alkalinization of 0.5% Ropivacaine by Adding Sodium Bicarbonate on Block Onset, Ending Time and Quality, and Postoperative Analgesic Efficiency for Peripheral Nerve Block in Unilateral Extremity Surgery." Turkiye Klinikleri Journal of Medical Sciences 33, no. 2 (2013): 326–33. http://dx.doi.org/10.5336/medsci.2012-28361.

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Okano, Alexandre Hideki. "Atividade cerebral relacionada ao apetite e exercício físico: implicações para a ingestão alimentar e controle do peso corporal." Revista Brasileira de Fisiologia do Exercício 11, no. 1 (November 13, 2019): 48. http://dx.doi.org/10.33233/rbfe.v11i1.3381.

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Conhecimentos sobre exercício físico e apetite são importantes tanto para atletas que almejam aumento do desempenho físico quanto para aqueles interessados na manutenção do peso corporal saudável. Componentes tanto homeostáticos quanto hedônicos, responsáveis pela sensação de prazer e atração pelo alimento controlam sinais de fome e saciedade em vias periféricas e centrais. Os sinais advindos da periferia fornecem informação sobre o estado nutricional corporal ao sistema nervoso central. Este último media e integra os sinais de fome e saciedade e após isto, formula uma resposta fisiológica que regula o comportamento alimentar do indivíduo. Pessoas obesas têm demonstrado diminuição expressiva da variabilidade da frequência cardíaca, aumento da atividade do nervo simpático, alteração do metabolismo hormonal e estimulação gástrica. Além disso, uma anormal atividade hipocampal foi identificada em resposta aos sinais de saciedade, comprometendo assim, todocontrole da ingestão alimentar de obesos. Esta anormal atividade neuronal persiste em indivíduos que já foram obesos, fazendo com que altos riscos ao reganho de peso possa ocorrer. A prática de exercício físico gera manutenção e perda do peso corporal, repercutindo tanto para melhorias no balanço energético quanto para o sistema de regulação do apetite. Estes benefícios parecem ser influenciados pela intensidade e duração do exercício.Palavras-chave: anorexia induzida pelo exercício, grelina, fome, saciedade, leptina.
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Alonderytė, Audrė, Robertas Stasys Samalavičius, and Pranas Šerpytis. "KARDIOVASKULINĖ RIZIKA IR FIZINIO AKTYVUMO POVEIKIS ATSKIROMS POPULIACIJOS GRUPĖMS. NAUJI ASPEKTAI." Health Sciences 30, no. 4 (August 8, 2020): 25–28. http://dx.doi.org/10.35988/sm-hs.2020.089.

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Tikslas – aptarti fizinio aktyvumo poveikį širdies ir kraujagyslių ligų rizikos veiksniams atskirose po­puliacijos grupėse. Metodika. Atlikta sisteminė mokslinės literatūros apž­valga. Duomenys buvo renkami PubMed duomenųbazėje. Analizuotos tik anglųkalba skelbtos publika­cijos, pasirodžiusios ne vėliau nei prieš5 metus. Ana­lizei atrinkta ir išanalizuota18 viso teksto publikacijų. Rezultatai. Reguliarus fizinis aktyvumas susijęs su rizikos mažinimu susirgti širdies ir kraujagyslių sis­temos ligomis [1]. Užsiimant reguliaria fizine veikla, gerėja ir tam tikri rodikliai, tokie kaip kūno masės indeksas, arterinis kraujospūdis, cholesterolio bei gliukozės kiekis kraujyje [2]. Idealių kardiovasku­linių komponentų kiekis vaikystėje lemia suaugu­siojo sveikatos būklę, todėl labai svarbu skatinti jaunų žmonių fizinį aktyvumą [3]. Fizinis aktyvumas re­komenduojamas ir vyresniems. Šioje populiacijoje fizinis aktyvumas mažina kritimų riziką ir su jais susijusią negalią, gerina bendrą gyvenimo kokybę [4]. Pacientams, sergantiems kardiovaskulinėmis li­gomis, rekomenduojamas vidutinio krūvio fizinis aktyvumas, nes didesnio krūvio fizinis aktyvumas neduoda geresnių bendrojo mirtingumo rezultatų[5]. Pastebėta, jog 12 savaičių fizinis aktyvumas padeda pagerinti arba netgi atkurti normalų atsaką į simpati­nės nervų sistemos stimuliaciją [1]. Fizinį aktyvumą įtraukiant į reabilitacijos po širdies ir kraujagyslių ligų programą, sumažėja pakartotinės hospitalizacijos rizika ir mirštamumas nuo kardiovaskulinių ligų [2]. Pacientai, sergantys periferinių kraujagyslių ligomis, mažiau vaikšto ir mankštinasi, todėl vyraujantis sė­dimas gyvenimo būdas didina susirgimo širdies ir kraujagyslių ligomis riziką. Svarbu atkreipti dėmesį į šią populiaciją, skatinant fizinį aktyvumą periferinų kraujagyslių ligomis sergančių pacientų grupėje [6].
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Lušaitė, Karolina, Nomeda Valevičienė, Dominyka Rimšaitė, and Marius Polianskis. "ŠIRDIES MAGNETINIO REZONANSO TOMOGRAFIJOS REIKŠMĖ ŠIRDIES AMILOIDOZĖS DIAGNOSTIKOJE." Medicinos teorija ir praktika 21, no. 4.1 (September 10, 2015): 507–17. http://dx.doi.org/10.15591/mtp.2015.080.

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Sisteminė amiloidozė yra reta liga, kuri gali pažeisti inkstus, odą, kraujagysles, centrinę ir periferinę nervų sistemą, plaučius, kepenis, žarnyną ir širdį. Širdies miokardą pažeidžiantys tipai yra lengvųjų grandinių (AL) amiloidozė, kai kurios įgimtos arba paveldimos amiloidozės formos (ATTR, AApoA-I), senilinė sisteminė amiloidozė (SSA), izoliuota prieširdžių amiloidozė ir antrinė amiloidozė. 2008–2013 metais atliktas retrospektyvinis tyrimas VUL SK Radiologijos ir branduolinės medicinos centre. Darbo tikslas buvo patikslinti širdies amiloidozės diagnostines galimybes, pasitelkiant širdies magnetinio rezonanso tomografiją (šMRT), palyginti gautus duomenis tarp kontrolinės ir sergančiųjų širdies amiloidoze grupių. Tai pat patikslinti amiloidozei būdingą kontrastinės medžiagos (k/m) kaupimo pobūdį, miokardo pakitimus, stebimus šMRT. Keturiolikai pacientų, įtariant širdies amiloidozę, atliktas šMRT tyrimas, įvertinant pacientų amžių, diagnostinius miokardo pakitimo požymius, k/m kaupimo pobūdį. ŠMRT jautriausias neinvazinis tyrimo metodas širdies amiloidozei nustatyti. Širdies amiloidozės atveju šMRT tyrimo metu nustatome koncentrinę skilvelių hipertrofiją, normalaus dydžio skilvelius, prieširdžių padidėjimą, TPP hipertrofiją. Taip pat galime nustatyti kitus pakitimus, būdingus amiloidozei, tokius kaip skystį perikarde, skystį pleuros ertmėse, trombus širdies kamerose. Širdies amiloidozės atveju širdies funkcija išlieka normali, kol liga nepažengia toli. Širdies amiloidozės atveju KS miokarde charakteringas ryškus difuzinis subendokardinis ar transmuralus k/m kaupimas, neatitinkantis koronarinių arterijų perfuzijos baseinų. Apibendrinus mūsų tyrimo rezultatus, sergant širdies amiloidoze, KS_IF nesumažėja, bet reikšmingai sustorėja TSP ir KSUS. Stebimas specifinis simptomas – difuzinis vėlyvas k/m kaupimas T1 sekoje, papildomai diagnozuojamas skystis pleuros ir perikardo ertmėje.
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Biasutto, Susana N., Gabriel A. F. Ceccón, Matías De la Rosa, and Paulina A. Bortolín. "THORAX-ABDOMINAL VAGUS NERVES IN FETUSES. Nervios vagos toraco-abdominales en fetos." Revista Argentina de Anatomía Clínica 7, no. 3 (March 28, 2016): 145–52. http://dx.doi.org/10.31051/1852.8023.v7.n3.14188.

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Los nervios vagos han sido exhaustivamente estudiados en los adultos pero no en los niños, y mayormente en el trayecto intracraneal, más que en la periferia. El objetivo de este estudio fue proveer información más específica sobre los nervios vagos toraco-abdominales, describirlos en fetos y asociarlos con la rotación gástrica, de modo que pueda ser aplicada a procedimientos clínicos, reduciendo la morbilidad. Se disecaron treinta fetos entre 12 y 23 semanas de gestación, mayormente varones (87%), desde la parte inferior del cuello hasta el cardias, identificando los troncos y ramas de los nervios vagos. Los nervios fueron descriptos en su ingreso en el tórax en relación con las arterias carótidas, en su posición en el tercio superior del esófago asociados con el origen de las ramas cardíacas y pulmonares, en el tercio inferior del esófago con muchas variaciones en su distribución, a nivel diafragmático en el hiato esofágico y, finalmente, en relación con la posición gástrica. La discusión involucró descripciones hechas por diferentes autores incluyendo algunos estudios recientes que proporcionan resultados electrofisio-lógicos y consideraciones de aspectos clínicos, principalmente representados por procedimientos quirúrgicos y su morbilidad, ambos asociados con la lesión de los nervios vagos. Vagus nerves have been extensively studied in adults but not in fetuses, and mostly in the intracranial pathway than the peripheral one. The objective of this study was to provide more specific information on the thorax-abdominal vagus nerves, to describe them in fetuses and to associate them with the gastric rotation, so it could be applied to clinical procedures, reducing morbidity. Thirty fetuses between 12 to 23 weeks of gestation, mainly male (87%), were dissected from the lower neck to the cardias, identifying vagus nerve trunks and braches. Vagus nerves were described at the entrance in the thorax in relation with the carotid arteries, in their position at the upper third of the esophagus associated with the origin of cardiac and pulmonary branches, in the lower third of the esophagus with many variations in their distribution, at the diaphragmatic level in the esophageal hiatus and, finally, in relation with the gastric position. The discussion involved descriptions made by different authors including some recent studies providing electrophysiological results and considerations on clinical aspects, mainly represented by surgical procedures and their morbidity associated, both to vagus nerve injury.
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Kimševaitė, Liudmila. "NEUROLOGINĖ PATOLOGIJA SERGANT 2 TIPO CUKRINIU DIABETU." Medicinos teorija ir praktika 22, no. 4 (January 10, 2017): 328–35. http://dx.doi.org/10.15591/mtp.2016.053.

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Reikšminiai žodžiai: cukrinis diabetas, neurologinė patologija, neurologinės komplikacijos. Darbo tikslas. Išanalizuoti 2 tipo cukriniu diabetu sergančių asmenų neurologinę patologiją. Tyrimo medžiaga ir metodai. Vilniaus miesto klinikinės ligoninės Vidaus ligų, Nefrologijos, I ir II angiochirurgijos, Urologijos skyriuose 2015 m. rugpjūtį – 2016 m. birželį tyrėme 102 2 tipo cukriniu diabetu sergančius ligonius (80 moterų ir 22 vyrus), kuriems buvo ar pasireiškė neurologinė patologija. Ligonių amžius 49–92 metai (vidurkis 73,2 ± 1,1 metų). Visiems ligoniams atliktas bendras kraujo tyrimas, nustatyta gliukozės koncentracija kraujo serume, glikozilintas hemoglobinas HbA1C, atlikta vidaus organų echoskopija, daliai ligonių – pilvo organų kompiuterinė tomografija (KT), esant indikacijoms – galvos (stuburo) KT, magnetinio rezonanso tomografija (MRT). Statistinių duomenų vidurkių skirtumai vertinti Stjudento patikimumo kriterijumi t. Skirtumai laikyti statistiškai patikimi esant p &lt; 0,05. Rezultatai. Išanalizuota sergančiųjų 2 tipo cukriniu diabetu neurologinė patologija. Galvos smegenų kraujotakos sutrikimai buvo 23 (22,5 proc.) ligoniams, diabetinė encefalopatija – 4 (3,9 proc.), diabetinė koma – 1 (1 proc.), hipoglikeminė koma – 1 (1 proc.), lėtinė galvos smegenų išemija – 10 (9,8 proc.), epilepsiniai priepuoliai – 3 (2,9 proc.), Parkinsono liga – 3 (2,9 proc.), diabetinė chorėja – 1 (1 proc.), diabetinė mielopatija – 1 (1 proc.), diabetinė periferinė neuropatija – 46 (45,1 proc.), diabetinė autonominė neuropatija – 3(2,9 proc.), peties rezginio neuropatija (plexopathia brachialis) – 1 (1 proc.), veidinio nervo neuropatija – 2 (2 proc.), vidurinio nervo neuropatija – 1 (1 proc.), meralgia paraesthetica – 2 (2 proc.). Galvos smegenų infarkto atveju, palyginus su sergančiųjų lėtine galvos smegenų išemija grupe, nustatyta statistiškai patikimai didesnė hiperglikemija: ženkliai padidėjęs gliukozės (11,08 ± 1,3 mmol/l, p &lt; 0,02), glikozilinto hemoglobino HbA1C (8,5 ± 1,2 proc., p &lt; 0,05) kiekis kraujyje. Lėtine galvos smegenų išemija sergančiųjų grupėje gliukozės kiekis kraujyje buvo 7,26 ± 0,4 mmol/l, glikozilinto hemoglobino HbA1C – 6,03 ± 0,2 proc. Padidėjęs gliukozės, glikozilinto hemoglobino HbA1C kiekis kraujyje, palyginus su sergančiųjų lėtine galvos smegenų išemija grupe, nustatytas ir praeityje galvos smegenų infarktą patyrusiems ligoniams – atitinkamai 8,65 ± 0,7 mmol/l ir 7,26 ± 0,4 mmol/l (p > 0,05), 7,2 ± 0,4 proc. ir 6,03 ± 0,2 proc. (p &lt; 0,01). Nustatyta sergančiųjų diabetine polineuropatija hiperglikemijos dydžio priklausomybė nuo cukrinio diabeto trukmės: sergančiųjų cukriniu diabetu daugiau kaip 10 metų, palyginus su sergančiųjų iki 5 metų grupe, gliukozės kiekis kraujyje buvo atitinkamai 9,93 ± 0,8 mmol/l ir 7,6 ± 0,7 mmol/l (p &lt; 0,05), glikozilinto hemoglobino HbA1C – 8,2 ± 0,3 proc. ir 5,78 ± 0,1 proc. (p &lt; 0,001). Sergančiųjų cukriniu diabetu nuo 5 iki 10 metų gliukozės kiekis kraujyje buvo 8,3 ± 1,0 mmol/l, (p > 0,05), glikozilinto hemoglobino HbA1C – 6,6 ± 0,4 proc. (p &lt; 0,05), palyginus su sergančiųjų cukriniu diabetu iki 5 metų grupe. Pateikti klinikiniai atvejai. Apžvelgta naujausia mokslinė literatūra apie sergančiųjų 2 tipo cukriniu diabetu neurologinę patologiją. Atliktų tyrimų duomenys palyginti su literatūros duomenimis. Išvados. Diabetinė polineuropatija yra dažniausia cukrinio diabeto komplikacija. Ji pasireiškia beveik pusei sergančiųjų cukriniu diabetu. Nustatyta sergančiųjų diabetine polineuropatija hiperglikemijos dydžio priklausomybė nuo cukrinio diabeto trukmės. Vidurinio nervo neuropatija yra ankstyva cukrinio diabeto komplikacija. Meralgia paraesthetica – skausminė neuropatija, susijusi su cukriniu diabetu. Cukriniu diabetu sergantiems ligoniams dažniau įvyksta aterotrombozinis insultas. Galvos smegenų infarkto atveju, palyginus su sergančiųjų lėtine galvos smegenų išemija grupe, nustatyta statistiškai patikimai didesnė hiperglikemija. Diabetinė encefalopatija – naujai pripažinta cukrinio diabeto komplikacija. Jos klinikinis spektras platus – nuo nežymios kognityvinės disfunkcijos iki demencijos. Epilepsiniai priepuoliai yra hiperglikemijos manifestacija. Jie gali būti pirminė klinikinė cukrinio diabeto apraiška. Neramių kojų sindromas dažnesnis diabetikams. Polineuropatija yra pagrindinis neramių kojų sindromo rizikos veiksnys sergant cukriniu diabetu.
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Permana, Hendra, and Meiti Frida. "PROFIL KECEPATAN HANTARAN SARAF PADA USIA MUDA." Majalah Kedokteran Andalas 37, no. 2 (May 3, 2015): 115. http://dx.doi.org/10.22338/mka.v37.i2.p115-120.2014.

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AbstrakKecepatan Hantaran Saraf (KHS) digunakan untuk menilai aktivitas saraf perifer. Nilai KHS dipengaruhi oleh faktor antropometrik, seperti Indeks Massa Tubuh (IMT). Beberapa studi mendapatkan perbedaan KHS pada beberapa tempat pemeriksaan. Tujuan penelitian ini adalah menilai KHS pada usia muda normal berdasarkan IMT. Ini adalah studi potong lintang terhadap komunitas Dokter Muda FK-Unand di bagian Ilmu Penyakit Saraf dari Januari sampai Mei 2011. Peserta dikelompokkan berdasarkan IMT <25 dan IMT ≥25. Penilaian KHS dilakukan pada saraf medianus, ulnaris, radialis, tibialis posterior dan peroneus komunis. F Wave dan H Reflex diukur menggunakan EMG. Data dianalisis dengan SPSS. Hasil studi didapatkan bahwa dari 53 subjek; 34 orang memiliki IMT <25 dan 19 orang dengan IMT ≥25. Pada kelompok IMT <25 didapatkan rerata usia 23,5 tahun, tinggi badan 1,69 m dan berat badan 64,32 kg, sedangkan kelompok IMT ≥25 didapatkan rerata usia 23,47 tahun, tinggi badan 1,66 m dan berat badan 73,58 kg. Terdapat pemanjangan latensi dan penurunan KHS sensorik serta pemanjangan latensi dan penurunan KHS motorik pada kelompok IMT ≥25 dibanding kelompok IMT <25. Kesimpulan penelitian ini adalah terdapat perbedaan bermakna KHS sensorik dan motorik nervus medianus berdasarkan IMT.AbstractNerve Conduction Velocity (NCV) can measure peripheral nerve activity. It was influenced by anthropometric, such as Body Mass Index (BMI). Previous studies suggested different results of NCV among different sites. The purpose of this study was to measure NCV among healthy young adult based on BMI. A cross sectional study was conducted to investigate NCV of fifth and sixth year medical students of Andalas University Padang from January to May 2011. Participants were categorized as BMI under 25 and 25 or above. NCV was examined on median, ulnar, radial, posterior tibial, and common peroneal nerves. F Waves and H Reflexes were measured using EMG. Data was analyzed by SPSS. The results from 53 participants; 34 had BMI under 25 and 19 had BMI 25 or above. On the group with BMI under 25, average age was 23.5 years olds, average height was 1.69, and average weight was 64.32 kg. On the group with BMI 25 or above, average age was 23.47 years olds, average height was 1.66 m, and average weight was 73.58 kg. There were prolonged latency and decreased NCV both sensoric and motoric on group with BMI 25 or above.
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Wijaya, Wilson Saputra, Mohammad Ridho Devantoro, and Hayyu Ari Anggriani. "Stroke Large Vessel Occlusion pada Serologi COVID-19 Positif." SCRIPTA SCORE Scientific Medical Journal 2, no. 2 (February 12, 2021): 145–55. http://dx.doi.org/10.32734/scripta.v2i2.4646.

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In December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appeared and caused COVID-19 in Wuhan, China. Of the 329 cases of COVID-19, the most common type of stroke was large vessel occlusion/LVO (31.7%) compared to small vessels (15.3%). A 73 year old man came in with weakness on the left side of his body since the day before after farming. Initially, the left leg felt limp, so the walk was limping, then the left hand seemed to be bent and could not be straightened. The head feels throbbing pain in the whole head. He had dysarthria since yesterday and when drinking, the patient chokes. His activity so far has only been farming near his house and he said there was no contact with people with fever or colds. He has a history of hypertension and is already taking Candesartan 8 mg every morning. Physical examination showed a blood pressure of 152/78 mmHg, pulse rate of 58 times per minute, respiratory rate of 20 times per minute, temperature of 36.8 oC, and 99% oxygen saturation with room air. Physical examination showed paralysis of seventh, tenth, and twelfth left cranial nerve. The muscle strength of the left hand and left leg is 2 out of 5, while the rest is normal. Eyeball movement is still possible, but both eyes often deviate to the right. Investigations for the results of random blood sugar, blood creatinine urea, and electrolytes were normal. The first day of chest X-ray showed calcification in the aorta and no infiltrate. On the fourth day, there were infiltrates to the periphery in both lung fields. This patient was diagnosed with LVO with acute infection and coagulopathy of COVID-19. Keywords: coagulopathy, COVID-19, large vessel occlusion Pada Desember 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) muncul dan memicu COVID-19 di Wuhan, Cina. Dari 329 kasus COVID-19, jenis stroke tersering berupa large vessel occlusion/LVO (31,7%) dibanding small vessel (15,3%). Seorang pria berusia 73 tahun datang dengan kelemahan pada sisi kiri badan sejak sehari sebelumnya setelah bertani. Awalnya kaki kiri dirasa lemas, sehingga jalannya pincang, lalu tangan kiri tampak menekuk dan tidak dapat diluruskan. Kepala dirasa nyeri berdenyut pada seluruh kepala. Bicara pasien pelo sejak kemarin dan bila minum, pasien tersedak. Aktivitasnya selama ini hanya bertani di dekat rumah dan mengaku tidak ada kontak dengan orang demam atau batuk-pilek. Dia memiliki riwayat hipertensi dan sudah mengonsumsi Candesartan 8 mg setiap pagi. Pemeriksaan fisik didapatkan tekanan darah 152/78 mmHg, laju nadi 58 kali per menit, laju pernapasan 20 kali per menit, temperatur 36,8 oC, dan saturasi oksigen 99% dengan udara ruangan. Pada pemeriksaan fisik tampak parese N. VII, X, XII sinistra. Kekuatan otot pada tangan kiri dan kaki kiri sebesar 2 dari 5, sementara yang lainnya normal. Gerakan bola mata masih dapat dilakukan, namun kedua mata sering deviasi ke arah kanan. Pada pemeriksaan penunjang didapatkan hasil gula darah sewaktu, ureum kreatinin darah, dan elektrolit normal. Foto thorax hari pertama tampak kalsifikasi pada aorta, tidak ada infiltrate dan pada hari keempat tampak infiltrat hingga ke perifer pada kedua lapang paru. Pasien ini didiagnosis LVO akibat infeksi akut dan koagulopati COVID-19. Kata Kunci: COVID-19, koagulopati, large vessel occlusion
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ULKAY, M. Başak, Abit AKTAŞ, Özgür AKSOY, Damla HAKTANIR, and H. Hakan BOZKURT. "Comparison of Fixation Methods for Peripheral Nerve Fiber." Kafkas Universitesi Veteriner Fakultesi Dergisi, 2013. http://dx.doi.org/10.9775/kvfd.2012.7098.

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ÖZATİK, Orhan, A. Aydan KÖSE, Atacan Emre KOÇMAN, İlknur DAĞ, Ahmet MUSMUL, and Tayfun ŞENGEL. "Periferik Sinirde Kronik Konstrüksiyon Hasarı Tedavisi Üzerine Dekompresyonun Etkisi." Kafkas Universitesi Veteriner Fakultesi Dergisi, 2016. http://dx.doi.org/10.9775/kvfd.2016.15126.

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Yurakh, Omelian, Oksana Popadynets, Halyna Yurakh, Mykhailo Osypchuk, Nadiya Tokaruk, Mariia Hryshchuk, and Taras Kotyk. "Cluster Analysis of Myelin Nerve Fibers of the Periferal Nerve." Archive of Clinical Medicine 26, no. 1 (June 25, 2020). http://dx.doi.org/10.21802/acm.2020.1.6.

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One of the unsolved issues in neuromorphology is the classification of myelin nerve fibers (MNF). Objective: to use cluster analysis to classify the sciatic nerve MNF. Material and methods. The work was performed using 5 one-year-old male Wistar rats. Semi-thin sections were stained with methylene blue. MNF morphometry was performed using ImageJ, and statistical processing – using the software environment R. Results of the study. Ward’s and k-means methods were used to cluster the MNF. Three clusters of MNFs are defined and their parameters are determined. The presented algorithm for adapting the literature data to the format of the obtained results includes determining the total average for the combined set of each indicator and the total variance, which is the sum of intragroup and intergroup variances. Conclusions: 1) for the classification of MNF it is advisable to use cluster analysis; 2) clustering should be performed according to the transsection areas of the axial cylinder and myelin sheath; 3) the number of clusters is determined by the agglomerative method of Ward, and their metrics – by the iterative method of k-means; 4) three clusters of MNF of the rat sciatic nerve differ in the transsection areas of the fibers, the axial cylinder and the myelin sheath and the percentage of nerve fibers; 5) when comparing identical indicators according to the obtained and literature data, the results were equivalent in the areas of the axial cylinder and myelin sheath and their shape coefficients, despite the fact that the classification of myelin fibers and their morphometry was performed using different methods.
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Hidayati, Hanik Badriyah, Paulus Sugianto, Junaidi Khotib, Chrismawan Ardianto, Kuntoro Kuntoro, and Mohammad Hasan Machfoed. "PENGUKURAN TINGKAH LAKU PADA MODEL NYERI NEUROPATIK PERIFER: TIKUS DENGAN CCI (CHRONIC CONSTRICTION INJURY)." Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia 35, no. 3 (June 1, 2018). http://dx.doi.org/10.52386/neurona.v35i3.15.

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BEHAVIORAL ASSESMENT OF THE PERIPHERAL NEUROPATHIC PAIN MODEL: RAT WITH CCI (CHRONIC CONSTRICTION INJURY)ABSTRACTNeuropathic pain occurs in 20% of patients with chronic pain. This mainly due to the lack of effective treatment and the presence of drug’s side effects. Animal models have been broadly utilized in validating the therapeutic target and the development of analgesic drugs. Chronic constriction injury (CCI) is a model of peripheral neuropathic pain characterized by allodynia and hyperalgesia. Chronic constriction injury model is produced by loose ligation of the sciatic nerve resulting in nerve damage, thus sensitizes and lowers pain threshold. The pain threshold test is performed by providing a pressure and thermal sensory stimulus that results in observable withdrawal behavior. This article discusses several methods in assessing pain-related behavior on the CCI neuropathic pain model.Keywords: Behavioral, chronic constriction injury, mechanical, neuropathic painABSTRAKNyeri neuropatik terjadi pada seperlima pasien dengan nyeri kronik. Hal ini disebabkan karena terapi nyeri neuropatik masih kurang efektif dan adanya efek samping obat. Model hewan terbukti bermanfaat untuk validasi target dan perkembangan obat analgesik. Chronic constriction injury (CCI) merupakan model nyeri neuropatik perifer dengan karakteristik alodinia dan hiperalgesia. Model CCI dibuat dengan memberikan ligasi longgar pada saraf skiatik yang menyebabkan kerusakan saraf, sehingga terjadi sensitisasi dan ambang nyeri menurun. Tes ambang nyeri dilakukan dengan memberikan stimulus sensorik berupa tekanan dan panas yang akan menghasilkan tingkah laku withdrawal yang bisa diobservasi. Artikel ini membahas penilaian tingkah laku nyeri pada model nyeri neuropatik CCI.Kata kunci: Chronic constriction injury, mekanik, nyeri neuropatik, tingkah laku
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Dewi, Windy Krisanti Kusuma, Uni Gamayani, Nushrotul Lailiyya, Lelani Reniarti, and Nanan Sekarwana. "HUBUNGAN KADAR HEMOGLOBIN DAN FERITIN DENGAN GAMBARAN KONDUKSI SARAF PADA ANAK TALASEMIA BETA MAYOR." Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia 35, no. 1 (December 1, 2017). http://dx.doi.org/10.52386/neurona.v35i1.42.

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CORRELATION BETWEEN HAEMOGLOBINE AND FERRITIN LEVEL WITH NERVE CONDUCTION STUDY IN CHILDREN WITH BETA THALASSEMIA MAJORABSTRACTIntroduction: Beta thalassemia major is inherited hemoglobin synthesis disorder found in thalassemia belt, including Indonesia. Peripheral neuropathy is one of its underdiagnosed neurological complications results in poor management of the patients.Aims: To identify correlation between hemoglobin and ferritin serum with Nerve conduction study (NCS) in Beta thalassemia major patients.Methods: This was a cross-sectional study involving children with beta thalassemia major aged 8-14 years, who regularly underwent blood transfusions in Hasan Sadikin Hospital, Bandung. Nerve conduction study of motor and sensory nerves of all limbs were conducted to the patients. Data was analyzed using Spearman’s correlation analysis.Results: Fifty subjects were included in this study with the mean hemoglobin level (SD) of 6.99 (0.87)g/dL and the mean blood ferritin level (SD) of 3.925 (1.993)μg/L. Based on NCS, most of the subjects had polyneuropathy and 46.94% had axonal demyelinating lesions in sensory and motor nerves. Among patients with neuropathy, there was a statistically significant negative correlation between mean hemoglobin level and the numbers of the abnormal nerves and also a statistically significant positive correlation between mean blood ferritin level and the numbers of the abnormal nerves.Discussion: The lower ferritin serum level, the less nerve involved based on NCS.Keyword: Beta thalassemia, ferritin, hemoglobin, nerve conduction study, neuropathyABSTRAKPendahuluan: Talasemia beta mayor merupakan suatu kelainan sintesis hemoglobin yang herediter yang banyak ditemukan di wilayah tropis, termasuk Indonesia. Salah satu komplikasinya adalah neuropati perifer yang sering tidak terdiagnosis, sehingga penyandangnya tidak mendapatkan tata laksana yang adekuat.Tujuan: Mengetahui hubungan antara kadar hemoglobin dan feritin serum dengan gambaran konduksi saraf (nerve conduction study/NCS) pada penyandang talasemia beta mayor.Metode: Studi potong lintang terhadap penyandang talasemia berusia 8-14 tahun yang rutin menjalani transfusi darah di RSUP Dr. Hasan Sadikin, Bandung. Dilakukan pemeriksaan NCS motorik dan sensorik pada keempat ekstremitas. Data dianalisis menggunakan uji korelasi Spearman.Hasil: Diperoleh 50 subjek dengan rerata kadar hemoglobin 6,99+0,87g/dL dan kadar feritin serum 3.925+1.993μg/L. Berdasarkan pemeriksaan NCS, sebagian besar subjek mengalami polineuropati yang 46,94% di antaranya berupa gambaran demielinasi aksonal sensorik motorik. Pada subjek dengan neuropati perifer didapatkan korelasi negatif yang bermakna antara kadar hemoglobin dengan jumlah keterlibatan saraf pada NCS dan korelasi positif yang bermakna antara kadar feritin serum dengan jumlah keterlibatan saraf pada NCS.Diskusi: Semakin rendah kadar feritin serum, maka semakin sedikit jumlah saraf yang terlibat pada NCS, dan sebaliknya.Kata kunci: Feritin, hemoglobin, nerve conduction study, neuropati, talasemia beta mayor
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Irawan, Devina, Audry Devisanty Wuysang, and Yudy Goysal. "HUBUNGAN KADAR LIPID DARAH DENGAN DERAJAT KEPARAHAN NEUROPATI DIABETIK PERIFER DI RUMAH SAKIT WAHIDIN SUDIROHUSODO." Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia 37, no. 1 (December 1, 2019). http://dx.doi.org/10.52386/neurona.v37i1.99.

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CORRELATION BETWEEN BLOOD LIPID LEVELS AND SEVERITY OF DIABETIC PERIPHERAL NEUROPATHY IN WAHIDIN SUDIROHUSODO HOSPITALABSTRACTIntroduction: Blood lipid levels play a role in the etiopathogenesis of diabetic neuropathy and have a significant relationship to the severity of diabetic neuropathy in patients with diabetes mellitus (DM).Aim: To assess the correlation between blood lipid levels and the severity of diabetic peripheral neuropathy (DPN) based on nerve conduction study (NCS).Methods: A cross-sectional study at Wahidin Sudirohusodo General Hospital, Makassar, consecutively from December 2018 to March 2019 on type 2 DM patients with DPN based on screening for diabetic neuropathy symptoms. HbA1C and blood lipid levels were examined, and DPN severity based on NCS was assessed using electromyoneurography (ENMG) with England criteria. One-way ANOVA was used for correlation analysis.Results: There were 56 subjects with an average age of 60.25 years old, the majority was women (51.8%) with DM duration ≥5 years (62.5%), HbA1C levels of patients ≥7% (55.4%), dyslipidemia (76.8%), and experienced severe DPN (55.4%). There was a significant relationship between blood lipid levels and the severity of DPN (p<0.05), especially in subjects with a patient’s HbA1C level <7%.Discussion: High lipid level plays a role in etiopathogenesis of diabetic neuropathy.Keywords: Blood lipid levels, diabetic peripheral neuropathy, HbA1CABSTRAKPendahuluan: Kadar lipid darah berperan dalam etiopatogenesis neuropati diabetik dan memiliki hubungan signifikan terhadap derajat keparahan neuropati diabetik pada pasien diabetes melitus (DM).Tujuan: Menilai hubungan kadar lipid darah dengan derajat keparahan neuropati diabetik perifer (NDP) berdasarkan Nerve Conduction Study (NCS).Metode: Penelitian potong lintang di RSUP Wahidin Sudirohusodo, Makassar, secara konsekutif periode Desember 2018-Maret 2019 terhadap pasien DM tipe 2 yang mengalami NDP berdasarkan skrining diabetic neuropathy symptoms. Dilakukan pemeriksaan kadar HbA1C dan lipid darah, serta penilaian derajat keparahan NDP berdasarkan KHS menggunakan alat elektromioneurografi (ENMG) dengan kriteria England. Analisis hubungan menggunakan uji one-way ANOVA.Hasil: Didapatkan 56 subjek dengan rerata usia 60,25 tahun, mayoritas perempuan (51,8%) dengan durasi DM ≥5 tahun (62,5%), kadar HbA1C pasien ≥7% (55,4%), dalam keadaan dislipidemia (76,8%), dan mengalami NDP berat (55,4%). Terdapat hubungan bermakna antara kadar lipid darah dan derajat keparahan NDP (p<0,05), terutama pada subjek dengan kadar HbA1C pasien <7%.Diskusi: Tingginya kadar lipid darah akan memperberat derajat keparahan NDP.Kata kunci: HbA1C, kadar lipid darah, neuropati diabetik perifer
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Gamayani, Uni, Fanny Adhy Putri, Nushrotul Lailiyya, Pandji Irani Fianza, and Ramdan Panigoro. "NEUROPATI PERIFER PADA PENYANDANG TALASEMIA DI POLIKLINIK HEMATO-ONKOLOGI RSUP DR. HASAN SADIKIN BANDUNG." Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia 36, no. 3 (September 28, 2020). http://dx.doi.org/10.52386/neurona.v36i3.75.

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PERIPHERAL NEUROPATHY IN THALASSEMIA PATIENTS AT HAEMATO-ONCOLOGY CLINIC HASAN SADIKIN GENERAL HOSPITAL BANDUNGABSTRACTIntroduction: Thalassemia is an inherited blood disorder with high prevalence that can lead to various neurological complications such as peripheral neuropathy. Peripheral neuropathy in thalassemia patients is commonly subclinical. Chronic hypoxia due to anemia and iron deposition are thought to be the risk factors for neuropathy in thalassemia. Nerve Conduction Study (NCS) is the gold standard in diagnosing peripheral neuropathy.Aims: To identify peripheral neuropathy among thalassemia patients in Hemato-oncology Clinic at Hasan Sadikin General Hospital, Bandung.Method: This was a cross sectional, observational descriptive study conducted on thalassemia patients who regularly underwent blood transfusion in Haemato-oncology Clinic at Hasan Sadikin General Hospital, Bandung. The study was held from November 2017 until March 2018. All subjects who met inclusion criteria and did not meet any exclusion criteria were assessed with neurological examination, Toronto clinical score and NCS.Results: Forty subjects with mean age 21.8±6.4 years old, 57.5% were female. The mean hemoglobin level was 7.3±0.7g/dL and mean ferritin serum level was 5,032±3,423μg/L. The median Toronto clinical s c o r e was 4 (0-7) with normal, mild neuropathy, and moderate neuropathy in 55%, 42.5%, and 2.5% subjects respectively. Ninety percent patients had abnormal NCS examination with axonal degeneration found in 57.5% subjects and polyneuropathy in 82.5% subjects.Discussion: Peripheral neuropathy were found in most adult thalassemia patients. Although, NCS examination is important to established definitive diagnosis and considered to be performed in thalassemia patients to diagnose peripheral neuropathy.Keywords: NCS, peripheral neuropathy, thalassemia, Toronto clinical scoreABSTRAKPendahuluan: Talasemia adalah penyakit kelainan darah herediter dengan prevalensi tinggi dan menimbulkan komplikasi neurologis berupa neuropati perifer. Neuropati perifer pada penyandang talasemia seringkali bersifat subklinis. Hipoksia jaringan akibat anemia kronis dan deposisi besi karena transfusi dicurigai sebagai faktor risiko terjadinya neuropati perifer pada talasemia. Standar baku diagnosis neuropati perifer adalah dengan pemeriksaan Kecepatan Hantar Saraf (KHS).Tujuan: Untuk mengetahui adanya neuropati perifer pada penyandang talasemia di Poliklinik Hemato-OnkologiMedik RSUP Dr. Hasan Sadikin, Bandung.Metode: Penelitian ini bersifat deskriptif observasional, dengan rancangan potong lintang, dilakukan pada subjek penyandang talasemia yang rutin menjalani transfusi di Poliklinik Hemato-Onkologi Medik RSUP Dr. Hasan Sadikin, Bandung. Penelitian dilakukan sejak November 2017 sampai Maret 2018. Seluruh subjek yang memenuhi kriteria inklusi dan tidak memiliki kriteria eksklusi dilakukan pemeriksaan neurologis, skor klinis Toronto dan KHS.Hasil: Sebanyak 40 subjek berusia rerata 21,8±6,4 tahun, 57,5% perempuan. Rerata kadar hemoglobin 7,3±0,7g/ dL dan rerata kadar feritin 5,032±3,423μg/L. Skor klinis neuropati Toronto didapatkan median 4 (0-7) dengan interpretasi tidak ada neuropati, neuropati ringan dan neuropati sedang berturut-turut pada 55%, 42,5%, dan 2,5% subjek. Sebanyak 90% subjek memiliki gambaran KHS abnormal, polineuropati didapatkan pada 82,5% subjek dan gambaran degenerasi aksonal pada 57,5% subjek.Diskusi: Neuropati perifer terjadi pada sebagian besar penyandang talasemia dewasa. Pemeriksaan KHS diperlukan untuk diagnosis pasti dan dipertimbangkan untuk dilakukan pada penyandang talasemia.Kata kunci: KHS, neuropati perifer, skor klinis Toronto, talasemia
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Djaali, Wahyuningsih, Christina Lanny Simadibrata, Irma Nareswari, Dwi Rachma Helianthi, and Kemas Abdurrohim. "PERAN TERAPI AKUPUNKTUR PADA CARPAL TUNNEL SYNDROME." Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia 37, no. 1 (December 1, 2019). http://dx.doi.org/10.52386/neurona.v37i1.103.

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ROLE OF ACUPUNCTURE THERAPY IN CARPAL TUNNEL SYNDROMEABSTRACTCarpal tunnel syndrome (CTS) is the most common peripheral neuropathy. In establishing a diagnosis of CTS, it requires several examinations that cannot stand alone. Symptoms from the anamnesis and signs of physical examination, such as Tinel test, Phalen test, press provocation examination, hand elevation examination and motor examination are needed. Nerve conduction velocity (NCV) investigation is also needed to diagnose CTS. Nevertheless, the clinical diagnosis of CTS can be done based on symptom history and physical examination using criteria by Rempel. Acupuncture is a modali- ty of non-pharmacological therapy performed by using fine needles at the acupuncture points. Acupuncture can improve the clinical symptoms of CTS patients through a mechanism of activation of the area in the brain that plays a role in sensory perception, through anti-inflammatory and anti-nociceptive mechanisms, and through mechanisms of protective effects on neural networks, thus providing therapeutic effects on neurological disorders due to CTS. By looking at the acupuncture mechanism, acupuncture can be a therapeutic choice for CTS to avoid the long-term side effects of medical therapy.Keywords: Acupuncture, carpal tunnel syndromeABSTRAKCarpal tunnel syndrome (CTS) merupakan neuropati perifer yang paling umum terjadi. Dalam menegakkan diagnosis CTS dibutuhkan beberapa pemeriksaan yang tidak dapat berdiri sendiri. Dibutuhkan gejala dari anamnesis, tanda dari pemeriksaan fisik, yaitu tes Tinel, tes Phalen, pemeriksaan provokasi tekan, pemeriksaan elevasi tangan dan pemeriksaan motorik. Juga dibutuhkan pemeriksaan penunjang kecepatan hantan saraf (KHS) untuk mendiagnosis pasti CTS. Sedangkan diagnosis klinis CTS dapat dilakukan berdasarkan anamnesis gejala dan pemeriksaan fisik dengan menggunakan kriteria oleh Rempel. Akupunktur merupakan modalitas terapi non-farmakologis yang dilakukan dengan penjaruman menggunakan jarum halus pada titik akupunktur. Akupunktur dapat memperbaiki gejala klinis pasien CTS melalui mekanisme aktivasi area di otak yang berperan pada persepsi sensorik, melalui mekanisme anti-inflamasi dan anti- nosiseptif, dan melalui mekanisme efek protektif pada jaringan saraf, sehingga memberikan efek terapeutik pada kelainan neurologis akibat CTS. Dengan melihat mekanisme akupunktur tersebut maka akupunktur dapat menjadi pilihan terapi pada CTS untuk menghindari efek samping jangka panjang dari terapi medikamentosa.Kata kunci: Akupunktur, carpal tunnel syndrome
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