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1

Domi, Rudin. "Postoperative Respiratory Complications." International Journal of Anesthetics and Anesthesiology 1, no. 1 (July 10, 2014): 1–2. http://dx.doi.org/10.23937/2377-4630/1002.

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McPherson, Kirstie, and Robert Stephens. "Postoperative respiratory complications." British Journal of Hospital Medicine 77, no. 4 (April 2, 2016): C60—C64. http://dx.doi.org/10.12968/hmed.2016.77.4.c60.

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Staehr-Rye, Anne K., and Matthias Eikermann. "Eliminate postoperative respiratory complications." European Journal of Anaesthesiology 32, no. 7 (July 2015): 455–57. http://dx.doi.org/10.1097/eja.0000000000000210.

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Platis, Cari Maria, Ludmyla Kachko, Evelyna Trabikin, Eliahu Simhi, Meshulam Bahar, and Jacob Katz. "Postoperative respiratory complications in Joubert syndrome." Pediatric Anesthesia 16, no. 7 (July 2006): 799–800. http://dx.doi.org/10.1111/j.1460-9592.2006.01864.x.

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Al-Rawi, Samar, and Kathy Nolan. "Respiratory Complications in the Postoperative Period." Anaesthesia & Intensive Care Medicine 4, no. 10 (October 2003): 332–34. http://dx.doi.org/10.1383/anes.4.10.332.27314.

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C. B., Praveen, and Imran Thariq Ajmal. "Clinical study of respiratory complications in patients undergoing elective upper abdominal surgery." International Surgery Journal 6, no. 3 (February 25, 2019): 732. http://dx.doi.org/10.18203/2349-2902.isj20190515.

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Background: Postoperative pulmonary complication is a major cause of morbidity, mortality, prolonged hospital stay and increased cost of care especially when it involves Upper Abdominal surgery. The predictable changes in lung function include a decrease in vital capacity and functional residual capacity, which are more striking in obese patients and in the supine. Aim is to study the incidence of respiratory complications in patients undergoing elective upper abdominal surgery with identification of risk factors namely Age, Sex, Obesity, Smoking and duration of upper abdominal Surgery for the development of Respiratory complications using a Peak Flow Meter as a bedside predictive test.Methods: Peak expiratory flow rate (PEFR) measurement daily up to 7 days post-surgery, were noted to monitor the occurrence of postoperative respiratory complications.Results: The study results according to our study showed that14 (34.1%) male patients out of 41 had postoperative complications as compared to 15 (48.3%) out of 31 female patients. 30.5% patients were obese and had postoperative complications of 9.75%. Overall 40% of smokers had postoperative complications. Postoperatively sub costal incision had complications (41%) in 36 patients, roof top incisions 4 out of 5 (80%) and para-umbilical incisions 3 out of 4 (75%). 80% of the patients who had upper abdominal transverse incisions developed microatelectasis followed by 75% of patients who had par median incisions.Conclusions: Respiratory complications following elective upper abdominal surgery are influenced by Increasing age and obesity and Smoking affected post-operative pulmonary recovery. Type of incision could also help change the incidence of complications.
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Ali, Zulfiqar. "Early postoperative respiratory complications following elective craniotomies." Journal of Neuroanaesthesiology and Critical Care 02, no. 02 (August 2015): 85–87. http://dx.doi.org/10.4103/2348-0548.155455.

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ANDERSON, P. R., M. R. PUNO, S. L. LOVELL, and C. R. SWAYZE. "Postoperative Respiratory Complications in Non-Idiopathic Scoliosis." Acta Anaesthesiologica Scandinavica 29, no. 2 (February 1985): 186–92. http://dx.doi.org/10.1111/j.1399-6576.1985.tb02183.x.

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Bai, Johnny W., Mandeep Singh, Anthony Short, Didem Bozak, Frances Chung, Vincent W. S. Chan, Anuj Bhatia, and Anahi Perlas. "Intrathecal Morphine and Pulmonary Complications after Arthroplasty in Patients with Obstructive Sleep Apnea." Anesthesiology 132, no. 4 (April 1, 2020): 702–12. http://dx.doi.org/10.1097/aln.0000000000003110.

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Abstract Background Intrathecal morphine is commonly and effectively used for analgesia after joint arthroplasty, but has been associated with delayed respiratory depression. Patients with obstructive sleep apnea may be at higher risk of postoperative pulmonary complications. However, data is limited regarding the safety of intrathecal morphine in this population undergoing arthroplasty. Methods This retrospective cohort study aimed to determine the safety of intrathecal morphine in 1,326 patients with documented or suspected obstructive sleep apnea undergoing hip or knee arthroplasty. Chart review was performed to determine clinical characteristics, perioperative events, and postoperative outcomes. All patients received neuraxial anesthesia with low-dose (100 μg) intrathecal morphine (exposure) or without opioids (control). The primary outcome was any postoperative pulmonary complication including: (1) respiratory depression requiring naloxone; (2) pneumonia; (3) acute respiratory event requiring consultation with the critical care response team; (4) respiratory failure requiring intubation/mechanical ventilation; (5) unplanned admission to the intensive care unit for respiratory support; and (6) death from a respiratory cause. The authors hypothesized that intrathecal morphine would be associated with increased postoperative complications. Results In 1,326 patients, 1,042 (78.6%) received intrathecal morphine. The mean age of patients was 65 ± 9 yr and body mass index was 34.7 ± 7.0 kg/m2. Of 1,326 patients, 622 (46.9%) had suspected obstructive sleep apnea (Snoring, Tired, Observed, Pressure, Body Mass Index, Age, Neck size, Gender [STOP-Bang] score greater than 3), while 704 of 1,326 (53.1%) had documented polysomnographic diagnosis. Postoperatively, 20 of 1,322 (1.5%) patients experienced pulmonary complications, including 14 of 1,039 (1.3%) in the exposed and 6 of 283 (2.1%) in the control group (P = 0.345). Overall, there were 6 of 1 322 (0.5%) cases of respiratory depression, 18 of 1,322 (1.4%) respiratory events requiring critical care team consultation, and 4 of 1,322 (0.3%) unplanned intensive care unit admissions; these rates were similar between both groups. After adjustment for confounding, intrathecal morphine was not significantly associated with postoperative pulmonary complication (adjusted odds ratio, 0.60 [95% CI, 0.24 to 1.67]; P = 0.308). Conclusions Low-dose intrathecal morphine, in conjunction with multimodal analgesia, was not reliably associated with postoperative pulmonary complications in patients with obstructive sleep apnea undergoing joint arthroplasty. Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New
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10

Bahr, Katherine L., Lisa Howe, Carl Jessen, and Zachary Goodrich. "Outcome of 45 Dogs With Laryngeal Paralysis Treated by Unilateral Arytenoid Lateralization or Bilateral Ventriculocordectomy." Journal of the American Animal Hospital Association 50, no. 4 (July 1, 2014): 264–72. http://dx.doi.org/10.5326/jaaha-ms-6081.

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The purpose of this retrospective study was to assess risk factors and complications affecting postoperative outcome of dogs with laryngeal paralysis treated by either unilateral arytenoid lateralization (UAL) or bilateral ventriculocordectomy (VCC). Medical records of all dogs having either UAL or VCC between 2000 and 2011 were analyzed. Twenty-five dogs had VCC and 20 dogs had UAL. The overall postoperative complications rates for VCC and UAL were similar (52% and 60%, respectively; P = .0887). Dogs that had UAL were more likely to have acute postoperative respiratory distress and aspiration pneumonia (P = .0526). Dogs with VCC were more likely to have chronic postoperative respiratory distress and aspiration pneumonia (P = .0079). Revision surgery was required in 6 dogs (24%) following VCC and 2 dogs (10%) following UAL. Sex, breed, presenting complaint, type of service provided, and concurrent diseases were not significantly associated with higher risk of either death or decreased survival time postoperatively with either procedure. Overall postoperative complication rates, required revision surgeries, and episodes of aspiration pneumonia were similar in dogs undergoing UAL and VCC surgeries. Dogs that had VCC appeared to have an increased risk of lifelong complications postoperatively compared with UAL; therefore, VCC may not be the optimal choice for treatment of laryngeal paralysis.
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Marrugo Pardo, G., L. F. Romero Moreno, P. Beltrán Erazo, and C. Villalobos Aguirre. "Respiratory Complications of Adenotonsillectomy for Obstructive Sleep Apnea in the Pediatric Population." Sleep Disorders 2018 (November 1, 2018): 1–6. http://dx.doi.org/10.1155/2018/1968985.

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Objective. To determine the prevalence of respiratory complications in the early postoperative period of children with sleep apnea who required adenotonsillectomy at a tertiary pediatric hospital and to establish recommendations for postoperative monitoring. Methods. Retrospective cohort study of children with obstructive sleep apnea (OSA) diagnosed by polysomnogram (PSG), who underwent adenotonsillectomy for treatment of OSA. The prevalence of respiratory complications in the first 24 postoperative hours was measured. Patients with craniofacial malformations, obesity, and severe cardiovascular comorbidities were excluded. The prevalence of postoperative respiratory complications was compared with the severity of OSA according to the Apnea Hypopnea Index (AHI) and NADIR. All data were taken in patients residing in Bogotá city, Colombia, at 2.640 meters above sea level (m.a.s.l). Results. Between May 2014 and February 2017, 167 patients (108 males) required adenotonsillectomy for OSA, with an age range of 1 and 15 years (mean 5.3 years +/- 2.7). The prevalence of postoperative respiratory complications was 3.59% (6/167). There was a statistically significant relationship between the presence of respiratory complication and AHI greater than 44/h (p <0.04). There was an inverse correlation between the AHI and NADIR values. Risk groups of patients younger than 3 years and NADIR less than 70% had a higher prevalence of respiratory complications; however, this correlation was not statistically significant (p <0.08 and 0.89, respectively). Conclusions. The prevalence of respiratory complications in OSA patients undergoing adenotonsillectomy in high altitudes is similar to that reported in other heights. Preoperative AHI greater than 44/h could be considered a risk factor for early respiratory complication. We suggest ambulatory management after 6 hours in Postanesthetic Care Unit (PACU) observation in patients older than 3 years, with AHI less than 44/h and NADIR greater than 70% in altitudes higher than 2.500 m.a.s.l. Further research must be done to confirm this hypothesis.
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ABE, Naoki, Kazuo NAKANISHI, Toshimitsu WATANABE, Toshihiro YOROZUYA, Tomoko ABE, and Takumi NAGARO. "Postoperative Respiratory Complications of Patients with Myotonic Dystrophy." JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA 31, no. 3 (2011): 468–72. http://dx.doi.org/10.2199/jjsca.31.468.

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YOKOTA, Miyuki, Ryozo MORINO, Makoto SEKI, and Tsutomu OSHIMA. "Importance of Postoperative Respiratory Complications in Perioperative Accidents." JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA 33, no. 1 (2013): 150–55. http://dx.doi.org/10.2199/jjsca.33.150.

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Sachdev, Gaurav, and Lena M. Napolitano. "Postoperative Pulmonary Complications: Pneumonia and Acute Respiratory Failure." Surgical Clinics of North America 92, no. 2 (April 2012): 321–44. http://dx.doi.org/10.1016/j.suc.2012.01.013.

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Oto, Jun. "Perioperative respiratory management to prevent postoperative pulmonary complications." Nihon Shuchu Chiryo Igakukai zasshi 25, no. 1 (2018): 3–11. http://dx.doi.org/10.3918/jsicm.25_3.

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Moores, Lisa K. "SMOKING AND POSTOPERATIVE PULMONARY COMPLICATIONS." Clinics in Chest Medicine 21, no. 1 (March 2000): 139–46. http://dx.doi.org/10.1016/s0272-5231(05)70013-7.

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Bilyy, Andrey, Tamer El-Nakhal, Jakub Kadlec, Waldemar Bartosik, Filip Van Tornout, and Vasileios Kouritas. "Preoperative training education with incentive spirometry may reduce postoperative pulmonary complications." Asian Cardiovascular and Thoracic Annals 28, no. 9 (September 11, 2020): 592–97. http://dx.doi.org/10.1177/0218492320957158.

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Objective To assess whether preoperative incentive spirometer training would influence the development of postoperative pulmonary complications after lung resection. Methods Sixty-two lung resection patients were prospectively investigated; 17 were given an incentive spirometer preoperatively and 45 did not have an incentive spirometer preoperatively. Postoperatively, both arms exercised with an incentive spirometer. The number of repetitions per day, balls raised per repetition, correct technique of exercising, and postoperative pulmonary complications were compared between the 2 groups. Univariate binary logistic regression analysis of potential predictors of postoperative pulmonary complications led to multivariate analysis of independent predictors. Receiver operating characteristic analysis established the cutoff points of predictors. Results The group with no preoperative incentive spirometer developed more postoperative pulmonary complications than the preoperative incentive spirometer group (24.4% vs. 5.9%, respectively, p = 0.045). The preoperative incentive spirometer arm achieved more repetitions per day, balls per repetition, and correct incentive spirometer technique ( p = 0.002, p < 0.001, p = 0.034, respectively). Balls raised per repetition and repetitions per day postoperatively were identified as independent predictors of postoperative pulmonary complications ( p = 0.032 and p = 0.021, respectively). Less than 5 repetitions per day (sensitivity 93%, specificity 77%, p < 0.001) and less than 2 balls per repetition (sensitivity 93%, specificity 77%, p < 0.001) were predictive of postoperative pulmonary complications. Conclusion Preoperative incentive spirometer exposure ensured better compliance with postoperative treatment and a more accurate technique (balls raised per repetition, repetitions per day). These variables correlated with a lower postoperative pulmonary complication rate.
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Lacoste, Louis, Nicole Montaz, Anne-Françoise Bernit, Damien Gineste, Marie-Suzanne Lehuede, Jacques Barbier, Jérôme Karayan, Martine Girault, and Jacques Fusciardi. "Airway Complications in Thyroid Surgery." Annals of Otology, Rhinology & Laryngology 102, no. 6 (June 1993): 441–46. http://dx.doi.org/10.1177/000348949310200607.

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Perioperative and postoperative morbidity and mortality were studied in a series of 3,008 thyroidectomies. Compressive symptoms, frequent in substernal and cancerous goiters, were present in 11.0% of the patients, although a low rate of dyspnea (2.7%) was observed. In large goiters, some orotracheal intubations were difficult. In such cases, the transtracheal approach can also be difficult, so failure should be anticipated. Postoperative causes of respiratory obstruction included local hemorrhages, bilateral recurrent nerve palsies, and laryngeal edema. A tracheal collapse was not observed. These respiratory obstructions led to repeat surgery in 11 patients, tracheostomy in 3, and temporary reintubation with steroid therapy in 1. The recurrent laryngeal nerve, which may have been affected preoperatively, was found to be damaged postoperatively in 0.5% of the patients with benign goiters, compared to 10.6% of the patients with thyroid cancer. In this last group a bilateral palsy was observed in 3 cases with prolonged or extensive surgery. After these short-term orotracheal intubations (114 minutes on average), injuries of the airway caused by the endotracheal tube were found in 4.6% of the patients.
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Sasaki, Nobuo, Matthew J. Meyer, and Matthias Eikermann. "Postoperative Respiratory Muscle Dysfunction." Anesthesiology 118, no. 4 (April 1, 2013): 961–78. http://dx.doi.org/10.1097/aln.0b013e318288834f.

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Abstract Postoperative pulmonary complications are responsible for significant increases in hospital cost as well as patient morbidity and mortality; respiratory muscle dysfunction represents a contributing factor. Upper airway dilator muscles functionally resist the upper airway collapsing forces created by the respiratory pump muscles. Standard perioperative medications (anesthetics, sedatives, opioids, and neuromuscular blocking agents), interventions (patient positioning, mechanical ventilation, and surgical trauma), and diseases (lung hyperinflation, obesity, and obstructive sleep apnea) have differential effects on the respiratory muscle subgroups. These effects on the upper airway dilators and respiratory pump muscles impair their coordination and function and can result in respiratory failure. Perioperative management strategies can help decrease the incidence of postoperative respiratory muscle dysfunction. Such strategies include minimally invasive procedures rather than open surgery, early and optimal mobilizing of respiratory muscles while on mechanical ventilation, judicious use of respiratory depressant anesthetics and neuromuscular blocking agents, and noninvasive ventilation when possible.
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WATANABE, Yosuke, Hitoshi YOKOYAMA, Yusuke KASAHARA, Hironobu KATATA, Maiko YAGI, and Teruyuki KOYAMA. "Examination of Postoperative Respiratory Complications after Pulmonary Resection Surgery." Rigakuryoho Kagaku 25, no. 3 (2010): 385–90. http://dx.doi.org/10.1589/rika.25.385.

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Katz, Sherri L., Andrea Monsour, Nicholas Barrowman, Lynda Hoey, Matthew Bromwich, Franco Momoli, Theodora Chan, et al. "Predictors of postoperative respiratory complications in children undergoing adenotonsillectomy." Journal of Clinical Sleep Medicine 16, no. 1 (January 15, 2020): 41–48. http://dx.doi.org/10.5664/jcsm.8118.

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Blatnik, Jeffrey A., David M. Krpata, Nicholas L. Pesa, Peter Will, Karem C. Harth, Yuri W. Novitsky, James R. Rowbottom, and Michael J. Rosen. "Predicting Severe Postoperative Respiratory Complications following Abdominal Wall Reconstruction." Plastic and Reconstructive Surgery 130, no. 4 (October 2012): 836–41. http://dx.doi.org/10.1097/prs.0b013e318262f160.

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Leo, Francesco, Piergiorgio Solli, Lorenzo Spaggiari, Giulia Veronesi, Filippo de Braud, Maria Elena Leon, and Ugo Pastorino. "Respiratory function changes after chemotherapy: an additional risk for postoperative respiratory complications?" Annals of Thoracic Surgery 77, no. 1 (January 2004): 260–65. http://dx.doi.org/10.1016/s0003-4975(03)01487-5.

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Madan, Karan, and Randeep Guleria. "Pulmonary complications in neurosurgical patients." Indian Journal of Neurosurgery 01, no. 02 (July 2012): 175–80. http://dx.doi.org/10.4103/2277-9167.102299.

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Abstract Pulmonary complications are a major cause of morbidity and mortality in neurosurgical patients. The common pulmonary complications in neurosurgical patients include pneumonia, postoperative atelectasis, respiratory failure, pulmonary embolism, and neurogenic pulmonary edema. Postoperative lung expansion strategies have been shown to be useful in prevention of the postoperative complications in surgical patients. Low tidal volume ventilation should be used in patients who develop acute respiratory distress syndrome. An antibiotic use policy should be put in practice depending on the local patterns of antimicrobial resistance in the hospital. Thromboprophylactic strategies should be used in nonambulatory patients. Meticulous attention should be paid to infection control with a special emphasis on hand-washing practices. Prevention and timely management of these complications can help to decrease the morbidity and mortality associated with pulmonary complications.
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Wilson, Kerryn, Indrani Lakheeram, Angie Morielli, Robert Brouillette, and Karen Brown. "Can Assessment for Obstructive Sleep Apnea Help Predict Postadenotonsillectomy Respiratory Complications?" Anesthesiology 96, no. 2 (February 1, 2002): 313–22. http://dx.doi.org/10.1097/00000542-200202000-00015.

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Background The aim of this study was to determine the frequency and type of respiratory complications after adenotonsillectomy in children. A second aim was to assess the ability of preoperative sleep studies to identify children at risk for respiratory complications. Methods Children referred for sleep studies between 1992 and 1998, who underwent adenotonsillectomy within 6 months of the preoperative study, were reviewed. The study focused on two variables: the obstructive apnea and hypopnea index and the oxygen saturation nadir. Medical charts were reviewed for postoperative respiratory complications. Results Three hundred forty-nine children were referred for sleep studies, and 163 met the inclusion criteria. Thirty-four children (21%) had postoperative respiratory complications requiring a medical intervention. Children experiencing respiratory complications were younger (aged &lt; 2 yr; adjusted odds ratio, 4.3; 95% confidence interval, 1.7-11) and had an associated medical condition (odds ratio, 3; 95% confidence interval, 1.4-6.5). A preoperative obstructive apnea and hypopnea index of 5 or more events per hour increased the chance of postoperative respiratory complications (odds ratio, 7.2; 95% confidence interval, 2.7-19.3), as did a preoperative oxygen saturation nadir of 80% or less (odds ratio, 6.4; 95% confidence interval, 2.8-14.5). A preoperative oxygen saturation nadir of 80% or less had a likelihood ratio of 3.1, increasing the probability of postoperative respiratory complications from 20 to 50%. Conclusions The data suggest, but do not prove, that preoperative nocturnal oximetry could be a useful preoperative test to identify children who are at increased risk for postoperative respiratory complications.
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Schizas, D., M. Frountzas, I. Lidoriki, E. Spartalis, K. Toutouzas, D. Dimitroulis, T. Liakakos, and KS Mylonas. "Sarcopenia does not affect postoperative complication rates in oesophageal cancer surgery: a systematic review and meta-analysis." Annals of The Royal College of Surgeons of England 102, no. 2 (February 2020): 120–32. http://dx.doi.org/10.1308/rcsann.2019.0113.

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Introduction The high morbidity and mortality rates after oesophagectomy indicate the need for rigorous patient selection and preoperative risk assessment. Although muscle mass depletion has been proposed as a potential prognostic factor for postoperative complications and decreased survival in gastrointestinal cancer patients, available data are conflicting. The purpose of the present meta-analysis is to determine whether sarcopenia predicts postoperative outcomes in patients undergoing oesophagectomy. Methods The databases MEDLINE, SCOPUS, Clinicaltrials.gov, CENTRAL and Google Scholar were searched for studies reporting on the effect of sarcopenia on postoperative outcomes following oesophageal cancer surgery. Outcomes included surgical complications, anastomotic leakage, respiratory complications, cardiovascular complications, postoperative infections, major complications and overall complications. The random effects model (DerSimonian–Laird) was used to calculate pooled effect estimates when high heterogeneity was encountered, otherwise the fixed-effects (Mantel–Haenszel) model was implemented. Findings A total of eight studies involving 1488 patients diagnosed with oesophageal cancer and who underwent oesophagectomy were included in the meta-analysis. The presence of sarcopenia did not significantly increase the rate of surgical complications (odds ratio, OR, 0.86, 95% confidence interval, CI, 0.40–1.85), anastomotic leakage (OR 0.75, 95% CI 0.42–1.35), respiratory complications (OR 0.56, 95% CI 0.21–1.48), cardiovascular complications (OR 0.94, 95% CI 0.31–2.83), postoperative infection (OR 1.14, 95% CI 0.52–2.50), major complications (OR 0.81, 95% CI 0.23–2.82) or overall postoperative complications (OR 0.80, 95% 0.32–1.99). Conclusion Sarcopenia does not seem to affect postoperative complication rates of patients undergoing oesophagectomy for oesophageal cancer. Future research should focus on determining whether prognosis differs according to muscle mass in this patient population.
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McLean, Duncan J., Daniel Diaz-Gil, Hassan N. Farhan, Karim S. Ladha, Tobias Kurth, and Matthias Eikermann. "Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications." Anesthesiology 122, no. 6 (June 1, 2015): 1201–13. http://dx.doi.org/10.1097/aln.0000000000000674.

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Abstract Background: Duration of action increases with repeated administration of neuromuscular-blocking agents, and intraoperative use of high doses of neuromuscular-blocking agent may affect respiratory safety. Methods: In a hospital-based registry study on 48,499 patients who received intermediate-acting neuromuscular-blocking agents, the authors tested the primary hypothesis that neuromuscular-blocking agents are dose dependently associated with the risk of postoperative respiratory complications. In the secondary analysis, the authors evaluated the association between neostigmine dose given for reversal of neuromuscular-blocking agents and respiratory complications. Post hoc, the authors evaluated the effects of appropriate neostigmine reversal (neostigmine ≤60 μg/kg after recovery of train-of-four count of 2) on respiratory complications. The authors controlled for patient-, anesthesia-, and surgical complexity–related risk factors. Results: High doses of neuromuscular-blocking agents were associated with an increased risk of postoperative respiratory complications (n = 644) compared with low doses (n = 205) (odds ratio [OR], 1.28; 95% CI, 1.04 to 1.57). Neostigmine was associated with a dose-dependent increase in the risk of postoperative respiratory complications (OR, 1.51; 95% CI, 1.25 to 1.83). Post hoc analysis revealed that appropriate neostigmine reversal eliminated the dose-dependent association between neuromuscular-blocking agents and respiratory complications (for neuromuscular-blocking agent effects with appropriate reversal: OR, 0.98; 95% CI, 0.63 to 1.52). Conclusions: The use of neuromuscular-blocking agents was dose dependently associated with increased risk of postoperative respiratory complications. Neostigmine reversal was also associated with a dose-dependent increase in the risk of respiratory complications. However, the exploratory data analysis suggests that the proper use of neostigmine guided by neuromuscular transmission monitoring results can help eliminate postoperative respiratory complications associated with the use of neuromuscular-blocking agents.
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Krdžalić, Goran, Emir Kabil, Urnid Salaka, Mirna Sijerčić, and Alisa Krdžalić. "Respiratory risk factors in development of postoperative complications after the lung resection." Bosnian Journal of Basic Medical Sciences 4, no. 3 (August 20, 2004): 55–58. http://dx.doi.org/10.17305/bjbms.2004.3395.

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The objectives of the study were to identify possible associated respiratory risk factors and to assess incidence of overall postoperative complications after the lung resection. We reviewed 110 patients who underwent lung resections due to malignant neoplasms or benign lung diseases. The risk of postoperative complications was evaluated using the univariate analysis. Results confirmed that low FEV1, postoperative high PaCO2, ASA-status and advanced age were factors associated with development of postoperative complications.
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S., Chauhan, Chauhan B., and Sharma H. "A comparative study of postoperative complications in emergency versus elective laparotomy at a tertiary care centre." International Surgery Journal 4, no. 8 (July 24, 2017): 2730. http://dx.doi.org/10.18203/10.18203/2349-2902.isj20173408.

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Background: The incidences of post-operative complications are higher after laparotomy particularly in emergency. This study was aimed to evaluate and compare postoperative complications after emergency versus elective laparotomy performed at Bundelkhand Medical College, Sagar.Methods: This comparative study was carried out at Department of General Surgery in Bundelkhand Medical College, Sagar, Madhya Pradesh during period of January 2015 to February 2016. All the patients who underwent laparotomy (elective or emergency) were included in the study. Demographic data about patients was collected and noted in pro forma. Patients were followed in postoperative period and any complication developed recorded. Complications compared according to nature of laparotomy whether elective or emergency.Results: A total of 350 patients underwent emergency laparotomy and 50 patients underwent elective laparotomy. 128 (36.57%) patients developed complications following emergency laparotomy while 11 (22%) patients developed complication after elective laparotomy. Postoperative complications following emergency laparotomy included pyrexia (18.2%) followed by nausea and vomiting (12%), wound infection (11.4%), respiratory tract infection (6.85%), urinary tract infection (2.28%), gastrointestinal complications (3.71%), toxemia and septicaemia (8%). After elective laparotomy 20% patients showed postoperative fever, 10% patients suffered from postoperative nausea and vomiting and wound infection was noted in 4% patients.Conclusions: In comparison to elective laparotomy postoperative complications are more common in emergency laparotomy.
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Borgi, Jamil, Ilan Rubinfeld, Jennifer Ritz, Jack Jordan, and Vic Velanovich. "The Differential Effects of Intermediate Complications with Postoperative Mortality." American Surgeon 79, no. 3 (March 2013): 261–66. http://dx.doi.org/10.1177/000313481307900324.

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Most attempts at understanding perioperative mortality have been based on assessing individual patient risk factors, types of operations, and hospital characteristics. The hypothesis of this study is that there is a relationship between postoperative mortality and postoperative complications; therefore, understanding this relationship may provide a basis for prevention and rescue. Using the 2007 SemiAnnual National Surgical Quality Improvement Program Report, we obtained data for each reporting hospital's rates of observed mortality, overall observed morbidity, observed cardiac, respiratory, renal complications, venothromboemoblic events (VTEs), surgical site infections (SSIs), and urinary tract infections (UTIs). Simple and multiple linear regression analyses were done comparing absolute rate of observed mortality with absolute rate of observed morbidity and each morbidity group. One hundred ninety-seven hospitals were included in the study. There were statistically significant associations between observed mortality rates and observed morbidity rates, cardiac complications, respiratory complications, and VTE rates. Renal complications, SSIs, and UTIs showed no statistically significant association with observed morbidity. This study demonstrates that rates of observed morbidity, especially cardiac, respiratory, and VTE complications, are associated with observed mortality. These findings suggest that care providers should focus efforts at prevention and rescue of cardiac, respiratory, and VTE complications.
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Pierce, William S., Laman A. Gray, Lawrence R. McBride, and O. Howard Frazier. "Panel 4 Other postoperative complications." Annals of Thoracic Surgery 47, no. 1 (January 1989): 96–101. http://dx.doi.org/10.1016/0003-4975(89)90248-8.

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Béchard, Philippe, Louis Létourneau, Yves Lacasse, Dany Côté, and Jean S. Bussières. "Perioperative Cardiorespiratory Complications in Adults with Mediastinal Mass." Anesthesiology 100, no. 4 (April 1, 2004): 826–34. http://dx.doi.org/10.1097/00000542-200404000-00012.

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Background Patients with a mediastinal mass are at risk for cardiorespiratory complications in the perioperative period. The authors' objectives were to evaluate the incidence of life-threatening intraoperative cardiorespiratory and postoperative respiratory complications in adult patients and to study the usefulness of clinical signs and symptoms, radiologic evaluation, and pulmonary function tests in the determination of the perioperative risk. Methods The authors reviewed the investigation and treatment of adult patients presenting with anterior or middle mediastinal masses for surgery under anesthesia between January 1994 and July 2000. Results Ninety-eight patients underwent 105 anesthetic cases. The incidences of intraoperative cardiorespiratory and postoperative respiratory complications were 4 in 105 and 11 in 105, respectively. No collapse of the airways occurred during anesthesia. However, a high incidence of early postoperative life-threatening respiratory complications was observed (7 in 105). In a multivariate logistic regression analysis model, perioperative complications were predicted by the occurrence of cardiorespiratory signs and symptoms at the initial presentation (odds ratio [OR], 6.2) and the presence of combined obstructive and restrictive patterns (mixed pulmonary syndrome) on pulmonary function tests (OR, 3.9). Intraoperative complications were associated with pericardial effusion on computed tomography scan (OR, 19.8). Postoperative respiratory complications were related to tracheal compression of more than 50% on preoperative computed tomography scan evaluation (OR, 7.4) and mixed pulmonary syndrome on pulmonary function tests (OR, 15.1). Conclusion Obstruction of the airway in an adult with a mediastinal mass is a rare event in the intraoperative period. Nevertheless, caution should be observed for the occurrence of early postoperative life-threatening respiratory complications. Patient at high risk of perioperative complications can be identified by the occurrence of cardiopulmonary signs and symptoms at presentation, combined obstructive and restrictive pattern on pulmonary function tests, and computed tomography scan findings (tracheal compression &gt; 50%, pericardial effusion, or both).
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Esmail, Nabil, Zorica Buser, Jeremiah R. Cohen, Darrel S. Brodke, Hans-Joerg Meisel, Jong-Beom Park, Jim A. Youssef, Jeffrey C. Wang, and S. Tim Yoon. "Postoperative Complications Associated With rhBMP2 Use in Posterior/Posterolateral Lumbar Fusion." Global Spine Journal 8, no. 2 (April 20, 2017): 142–48. http://dx.doi.org/10.1177/2192568217698141.

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Study Design: Retrospective database review. Objective: Posterior/posterolateral lumbar fusion (PLF) is an effective treatment for a variety of spinal disorders; however, variations in surgical technique have different complication profiles. The aim of our study was to quantify the frequency of various complications in patients undergoing PLF with and without human recombinant bone morphogenetic protein 2 (rhBMP2). Methods: We queried the orthopedic subset of the Medicare database (PearlDiver) between 2005 and 2011 for patients undergoing PLF procedures with and without rhBMP2. Complication and reoperation rates were analyzed within 1 year of the index procedure. Complications assessed include: acute renal failure, deep vein thrombosis, dural tear, hematoma, heterotopic ossification, incision and drainage, cardiac complications, nervous system complications, osteolysis, pneumonia, pseudarthrosis, pulmonary embolism, radiculopathy, respiratory complications, sepsis, urinary retention, urinary tract infection, mechanical, and wound complications. Chi-square analysis was used to calculate the complication differences between the groups. Results: Our data revealed higher overall complication rates in patients undergoing PLF with rhBMP2 versus no_rhBMP2 (76.9% vs 68.8%, P < .05). Stratified by gender, rhBMP2 males had higher rates of mechanical complications, pseudarthrosis, and reoperations compared with no_rhBMP2 males ( P < .05), whereas rhBMP2 females had higher rates of pseudarthrosis, urinary tract infection, and urinary retention compared with no_rhBMP2 females ( P < .05). Conclusion: Our data revealed higher overall complication rates in PLF patients given rhBMP2 compared with no_rhBMP2. Furthermore, our data suggests that rhBMP2-associated complications may be gender specific.
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Gribble, Amy, and Ee-Min Wong. "Residual neuromuscular block – a neglected cause of postoperative respiratory complications." Trends in Anaesthesia and Critical Care 30 (February 2020): e114. http://dx.doi.org/10.1016/j.tacc.2019.12.279.

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Allen, Gary S., Charles S. Cox, Nicki White, Samia Khalil, Mary Rabb, and Kevin P. Lally. "Postoperative respiratory complications in ex-premature infants after inguinal herniorrhaphy." Journal of Pediatric Surgery 33, no. 7 (July 1998): 1095–98. http://dx.doi.org/10.1016/s0022-3468(98)90538-3.

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Le, Lan My, and Nathorn Chaiyakunapruk. "Urgent need to take action on reducing postoperative respiratory complications." Lancet Regional Health - Western Pacific 10 (May 2021): 100136. http://dx.doi.org/10.1016/j.lanwpc.2021.100136.

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Ball, Lorenzo, Marcelo Gama de Abreu, Marcus J. Schultz, and Paolo Pelosi. "Neuromuscular blocking agents and postoperative pulmonary complications." Lancet Respiratory Medicine 7, no. 2 (February 2019): 102–3. http://dx.doi.org/10.1016/s2213-2600(18)30363-1.

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Takahashi, Yusuke, and Shigeki Suzuki. "Preoperative pulmonary function testing and postoperative complications." Journal of Thoracic Disease 10, S33 (November 2018): S3840—S3842. http://dx.doi.org/10.21037/jtd.2018.09.37.

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39

Brown, Karen A., Isabelle Morin, Chantal Hickey, John J. Manoukian, Gillian M. Nixon, and Robert T. Brouillette. "Urgent Adenotonsillectomy." Anesthesiology 99, no. 3 (September 1, 2003): 586–95. http://dx.doi.org/10.1097/00000542-200309000-00013.

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Background The aim of this study was to determine the frequency and type of respiratory complications after urgent adenotonsillectomy (study group) for comparison with a control group of children undergoing a sleep study and adenotonsillectomy for obstructive sleep apnea syndrome. A second aim was to assess risk factors predictive of respiratory complications after urgent adenotonsillectomy. Methods The perioperative course of children who underwent adenotonsillectomy between January 1, 1999, and March 31, 2001, was reviewed. Two groups of children were identified from two different databases: the hospital database for surgical procedures (the study group) and the sleep laboratory database (the control group). The retrospective chart review focused on the preoperative status (including an evaluation for obstructive sleep apnea), anesthetic management, and need for postoperative respiratory interventions. Results A total of 64 consecutive cases for urgent adenotonsillectomy were identified, and 54 children met the inclusion criteria. Thirty-three children (60%) had postoperative respiratory complications necessitating a medical intervention; 11 (20.3%) required a major intervention (reintubation, ventilation, and/or administration of racemic epinephrine or Ventolin), and 22 (40.7%) required a minor intervention (oxygen administration). Six children (11.1%) required reintubation in the recovery room for respiratory compromise. Risk factors for respiratory complications were an associated medical condition (odds ratio, 8.15; 95% confidence interval, 1.81-36.73) and a preoperative saturation nadir less than 80% (odds ratio, 5.54; 95% confidence interval, 1.15-26.72). Sixteen (49%) of the medical interventions were required within the first postoperative hour. Atropine administration, at induction, decreased the risk of postoperative respiratory complications (odds ratio, 0.18; 95% confidence interval, 0.11-1.050. Control Group Of 75 children who underwent a sleep study and adenotonsillectomy, 44 had sleep apnea and were admitted to hospital after elective adenotonsillectomy. Sixteen (36.4%) children had postoperative respiratory complications necessitating a medical intervention. Six percent of the children (n = 3) required a major medical intervention. No child required reintubation for respiratory compromise. Conclusions Severe obstructive sleep apnea syndrome and an associated medical condition are risk factors for postadenotonsillectomy respiratory complications. Risk reductions strategies should focus on their assessment.
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Çınar, Hüseyin Ulaş. "Is respiratory physiotherapy effective on pulmonary complications after lobectomy for lung cancer?" Turkish Journal of Thoracic and Cardiovascular Surgery 28, no. 4 (October 22, 2020): 638–47. http://dx.doi.org/10.5606/tgkdc.dergisi.2020.19693.

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Background: The aim of this study was to investigate the effects of a postoperative respiratory physiotherapy program on pulmonary complications, length of hospital stay, and hospital cost after lobectomy for lung cancer. Methods: A total of 90 patients (75 males, 15 females; mean age 63.1±10.4 years; range, 30 to 82 years) who underwent elective lobectomy through thoracotomy due to lung cancer between June 2014 and December 2019 were retrospectively analyzed. The patients were divided into two groups as Group S who received standard postoperative care (n=50) and Group P who received postoperative respiratory physiotherapy in addition to standard care (n=40). Both groups were compared in terms of postoperative pulmonary complications, 30-day mortality, length of hospital stay, and hospital cost. Results: The preoperative and surgical characteristics of the groups were similar. Group P had a lower incidence of postoperative pulmonary complications (10% vs. 38%, respectively; p=0.002) than Group S. The median length of stay in the hospital was six (range, 4 to 12) days in Group P and seven (range, 4 to 40) days in Group S (p=0.001). The drug cost (639.70 vs. 1,211.46 Turkish Liras, respectively; p=0.001) and the total hospital cost (2,031.10 vs. 3,778.68 Turkish Liras, respectively; p=0.001) of the patients in Group P were significantly lower. The multivariate logistic regression analysis showed that respiratory physiotherapy had a protective effect on the development of postoperative pulmonary complications (odds ratio =0.063, 95% confidence interval: 0.010-0.401, p=0.003). Conclusion: An intensive physiotherapy program focusing on respiratory exercises is a cost-effective practice which reduces the risk of development of postoperative pulmonary complications in patients undergoing lobectomy for lung cancer.
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Hanada, Masatoshi, Kota Yamauchi, Shinjiro Miyazaki, Yohei Oyama, Yorihide Yanagita, Shuntaro Sato, Takuro Miyazaki, Takeshi Nagayasu, and Ryo Kozu. "Short-Physical Performance Battery (SPPB) score is associated with postoperative pulmonary complications in elderly patients undergoing lung resection surgery: A prospective multicenter cohort study." Chronic Respiratory Disease 17 (January 1, 2020): 147997312096184. http://dx.doi.org/10.1177/1479973120961846.

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Elderly patients awaiting lung resection surgery often have poor physical function, which puts them at a high risk of postoperative pulmonary complications. The aim of this study was to investigate the impact of preoperative physical performance on postoperative pulmonary complications in patients awaiting lung resection surgery. In this prospective multicenter cohort study, the characteristics of patients and postoperative pulmonary complications were compared between subjects with low (<10) and high (≥10) Short Physical Performance Battery (SPPB) scores. Postoperative pulmonary complications were defined as over grade II in Clavien-Dindo classification system. We estimated the effects of physical performance on postoperative pulmonary complications using multivariable hierarchical logistic regression. The postoperative pulmonary complications were compared between 331 patients in the high and 33 patients in the low SPPB group. Patients in the low SPPB score group had a significantly higher rate of postoperative pulmonary complications (p < 0.001). Low SPPB score was associated with a higher risk of postoperative pulmonary complications (odds ratio, 8.80; p < 0.001). The SPPB is a clinically useful evaluation tool to assess surgical patients’ physical performance. The low physical performance indicated by the SPPB may be predictive of postoperative pulmonary complications after lung resection surgery. Trial registration: Clinical Trials. University hospital Medical Information Network Center (UMIN-CTR) UMIN000021875.
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Barrera, Shelby C., Evan J. Sanford, Sarah B. Ammerman, Jay K. Ferrell, C. Blake Simpson, and Laura M. Dominguez. "Postoperative Complications in Obese Patients After Tracheostomy." OTO Open 4, no. 3 (July 2020): 2473974X2095309. http://dx.doi.org/10.1177/2473974x20953090.

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Objective To determine the prevalence of varying classes of obesity in patients undergoing tracheostomy and the associated complication rates as compared with nonobese patients. Study Design A retrospective chart review was performed from 2012 to 2018 on all patients who underwent open tracheostomy by the Department of Otolaryngology–Head and Neck Surgery. Setting All tracheostomies were performed at a single tertiary care center. Methods Patients were classified by body mass index (BMI) according to the World Health Organization classification system: underweight (<18.5), normal-overweight (18.5-29.9), class I (30-34.9), class II (35-39.9), and class III (>40). Charts were reviewed for patient demographic information, Charlson Comorbidity Index score, surgical indication, operative time, tracheostomy tube type, and postoperative complications. Results A total of 387 patients (mean ± SD BMI, 31.3 ± 14.2) were identified per the inclusion/exclusion criteria. Of patients with BMI >30 (n=153), 34.6% were categorized as obesity class I, 29.4% as class II, and 35.9% as class III. The most common indication for tracheostomy was malignancy in nonobese patients (41.5%) and respiratory failure for obese patients (58.2%). Operative time was significantly longer in obese patients, and most of these patients required an extended-length tracheostomy tube. Patients with a BMI >40 had higher rates of multiple postoperative complications or death ( P = .009). Underweight patients also had a higher rate of complication than normal-overweight patients ( P = .016). Conclusion Class III and underweight patients had higher rates of postoperative complications, which should be taken into consideration during perioperative counseling.
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Pereira, Eanes Delgado Barros, Ana Luisa Godoy Fernandes, Meide da Silva Anção, Clóvis de Araújo Peres, Álvaro Nagib Atallah, and Sonia Maria Faresin. "Prospective assessment of the risk of postoperative pulmonary complications in patients submitted to upper abdominal surgery." Sao Paulo Medical Journal 117, no. 4 (July 1999): 151–60. http://dx.doi.org/10.1590/s1516-31801999000400003.

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OBJECTIVE: To investigate associations between preoperative variables and postoperative pulmonary complications (PPC) in elective upper abdominal surgery. DESIGN: Prospective clinical trial. SETTING: A tertiary university hospital. PATIENTS: 408 patients were prospectively analyzed during the preoperative period and followed up postoperatively for pulmonary complications. MEASUREMENTS: Patient characteristics, with clinical and physical evaluation, related diseases, smoking habits, and duration of surgery. Preoperative pulmonary function tests (PFT) were performed on 247 patients. RESULTS: The postoperative pulmonary complication rate was 14 percent. The significant predictors in univariate analyses of postoperative pulmonary complications were: age >50, smoking habits, presence of chronic pulmonary disease or respiratory symptoms at the time of evaluation, duration of surgery >210 minutes and comorbidity (p <0.04). In a logistic regression analysis, the statistically significant predictors were: presence of chronic pulmonary disease, surgery lasting >210 and comorbidity (p <0.009). CONCLUSIONS: There were three major clinical risk factors for pulmonary complications following upper abdominal surgery: chronic pulmonary disease, comorbidity, and surgery lasting more than 210 minutes. Those patients with three risk factors were three times more likely to develop a PPC compared to patients without any of these risk factors (p <0.001). PFT is indicated when there are uncertainties regarding the patient’s pulmonary status.
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44

Rahman, Ganiyu A. "Possible Risk Factors for respiratory Complications after Thyroidectomy: An Observational Study." Ear, Nose & Throat Journal 88, no. 4 (April 2009): 890–92. http://dx.doi.org/10.1177/014556130908800415.

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It is widely accepted that thyroid surgery is not without morbidity. One well known postoperative complication is respiratory distress. The aim of this prospective observational study was to determine the incidence of post-thyroidectomy respiratory complications and to identify possible predictive factors. The study population was made up of 262 patients who had undergone thyroidectomy for goiter at the University of Ilorin Teaching Hospital in Nigeria from January 1989 through December 2003. Information was collected on 8 possible predictive factors for respiratory complications: (1) the duration of the goiter, (2) the preoperative status of the recurrent laryngeal nerve, (3) the presence or absence of tracheal narrowing or deviation, (4) the presence or absence of retrosternal extension, (5) the ease or difficulty of endotracheal intubation, (6) the presence or absence of thyroid cancer, (7) the presence or absence of giant goiter, and (8) whether or not the goiter represented a recurrence. Respiratory complications occurred in 20 of the 262 patients (7.6%). Of these 20 patients, 16 (80%) had a goiter of at least 5 years’ duration, 12 (60%)) had a giant goiter, 5 (25%) had tracheal narrowing, 4 (20%) had a malignant goiter, 3 (15%) had palsy of the recurrent laryngeal nerve preoperatively, and 2 patients each (10%) had retrosternal extension, a difficult intubation, or a recurrent goiter. Twelve patients (60%) had at least 4 of the 8 possible risk factors, and 6 others (30%) had 3 factors. Postoperative tracheotomy was necessary for 4 patients. No deaths occurred. While the findings of this observational study can only suggest the possibility of causation, preoperative factors such as long-standing goiter and giant goiter should be taken into consideration in postoperative management and the prevention of respiratory complications. In addition, the presence of at least 4 of the 8 factors studied should likewise alert the management team.
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Duldulao, Marjun P., Wendy Lee, Maithao Le, Rebecca Wiatrek, Rebecca A. Nelson, Zhenbin Chen, Wenyan Li, Joseph Kim, and Julio Garcia-Aguilar. "Surgical Complications and Pathologic Complete Response after Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer." American Surgeon 77, no. 10 (October 2011): 1281–85. http://dx.doi.org/10.1177/000313481107701001.

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Pathologic complete response (pCR) to neoadjuvant chemoradiation (CRT) in patients with rectal cancer is associated with improved prognosis, whereas postoperative surgical complications have been linked with poor oncologic outcomes. Our objective was to examine the association between postoperative complications and pCR. We analyzed 127 patients enrolled in a prospective multicenter study investigating rectal cancer response to CRT. Surgical complications were scored according to the Clavien-Dindo scale (Grade 1 to 4). Among the 127 patients analyzed, 28 (22%) patients had a pCR. In the pCR group, six surgical Grade 3+ complications occurred in five (18%) patients, including anastomotic leak (n = 2), ureteral injury (n = 2), pelvic abscess (n = 1), and pneumonia (n = 1). In the non-pCR group, there were 10 Grade 3+ complications in eight (8%) patients, including severe obstruction (n = 1), postoperative hemorrhage (n = 1), leak (n = 2), pelvic abscess (n = 2), ureteral injury (n = 1), and severe morbidity (stroke, n = 1; acute respiratory distress, n = 1; and cardiac event, n = 1). There was no significant difference in the frequency of total surgical complications between pCR and non-pCR patients; and no association was observed between pCR and major postoperative complications. In conclusion, postoperative complication rates do not differ between pCR and non-pCR groups. The occurrence of major postoperative complications is not associated with response to neoadjuvant CRT.
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Ahmadinejad, Mojtaba, Mozaffar Hashemi, and Nasim Azizallahi. "Evaluation of Prognostic Factors Associated with Postoperative Complications Following Pulmonary Hydatid Cyst Surgery." Open Respiratory Medicine Journal 14, no. 1 (July 21, 2020): 16–21. http://dx.doi.org/10.2174/1874306402014010016.

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Background: Hydatid cysts are one of the serious complications following echinococcus infection. The liver and the lungs are the most affected organs, respectively. The severity of the disease is associated with the increase in the number and the size of the cysts, cysts rupture, and systemic effects. The aim of this study is to evaluate prognostic factors that are associated with the increased incidence of postoperative complications following pulmonary hydatid cyst surgery. Methods: Patients referred to Madani hospital from 2014-2018, presenting pulmonary hydatid cysts were included in this study. All the patients were evaluated based on the following parameters: age, gender, location and size of the cysts, rupture status of the cysts (intact or perforated), type of surgical intervention (capitonnage or segmentectomy) and Erythrocyte Sedimentation Rate (ESR). The factors were then compared with postoperative complications. Statistical analysis of the data obtained was conducted using R-software Results: Of 76 patients enrolled in our study, 52.63% were males and 47.36% were female. Air leak complication was reported in 13.15% of the patients and 3.94% of the patients were presented with pleural effusion. Postoperative complications were significantly associated with the perforated (ruptured) cysts p= 0.001, segmentectomy p= 0.013, giant hydatid cysts p= 0.007 and ESR p= 0.014. However, the side of the lung was not significantly related to postoperative complications. Conclusion: Our study reports that perforated cysts, increased size, segmentectomy and abnormal ESR are likely to increase postoperative complications following pulmonary hydatid cysts surgery. Prospective studies with perioperative parameters and greater sample size can help to deduce better inferences.
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Harden, Brandon, Xin Tian, Rachel Giese, Nader Nakhleh, Safina Kureshi, Richard Francis, Sridhar Hanumanthaiah, et al. "Increased postoperative respiratory complications in heterotaxy congenital heart disease patients with respiratory ciliary dysfunction." Journal of Thoracic and Cardiovascular Surgery 147, no. 4 (April 2014): 1291–98. http://dx.doi.org/10.1016/j.jtcvs.2013.06.018.

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48

Yamana, Ippei, Shinsuke Takeno, Tatsuya Hashimoto, Kenji Maki, Ryosuke Shibata, Hironari Shiwaku, Hideki Shimaoka, Etsuji Shiota, and Yuichi Yamashita. "Randomized Controlled Study to Evaluate the Efficacy of a Preoperative Respiratory Rehabilitation Program to Prevent Postoperative Pulmonary Complications after Esophagectomy." Digestive Surgery 32, no. 5 (2015): 331–37. http://dx.doi.org/10.1159/000434758.

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Background/Aims: Patients with postoperative pulmonary complications after esophagectomy often have increased mortality. The purpose of the study was to examine the efficacy of preventing postoperative pulmonary complications by an intensive preoperative respiratory rehabilitation (PR) program for esophageal cancer patients. Methods: This study was a prospective randomized controlled study. Thirty patients in the PR group and 30 patients in the no preoperative respiratory rehabilitation (NPR) group were included. The PR group received preoperative rehabilitation for more than 7 days, while the NPR group did not receive any preoperative rehabilitation. All patients underwent postoperative rehabilitation from the first postoperative day. The postoperative pulmonary complications were evaluated using the Clavien-Dindo classification (CDC) and the Utrecht Pneumonia Scoring System (UPSS). Results: The CDC grade in the PR group was significantly lower than that in the NPR group (p = 0.014). The UPSS score in the PR group was significantly lower than that in the NPR group at postoperative day 1 (p = 0.031). In the multivariate analysis, NPR was an independent risk factor for postoperative pulmonary complications greater than CDC grade II (OR: 3.99, 95% CI: 1.28-12.4, p = 0.017). Conclusions: This study showed that the intensive PR program was capable of reducing the postoperative pulmonary complications in esophageal cancer patients.
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Stæhr, Anne K., Christian S. Meyhoff, and Lars S. Rasmussen. "Inspiratory Oxygen Fraction and Postoperative Complications in Obese Patients." Anesthesiology 114, no. 6 (June 1, 2011): 1313–19. http://dx.doi.org/10.1097/aln.0b013e31821bdb82.

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Background Obese patients are at a high risk of postoperative complication, including surgical site infection (SSI). Our aim was to evaluate the effect of a high inspiratory oxygen fraction (80%) on SSI and pulmonary complications in obese patients undergoing laparotomy. Methods This study was a planned analysis of the obese patients (body mass index ≥ 30 kg/m²) recruited in the Danish multicenter, patient- and observer-blinded, PROXI Trial of 1,400 patients undergoing acute or elective laparotomy. Patients were randomized to receive either 80% or 30% oxygen during and for 2 h after surgery. The primary outcome was SSI within 14 days. Secondary outcomes were atelectasis, pneumonia, and respiratory failure. Results Two hundred thirteen patients had a body mass index ≥ 30 kg/m². The median (5-95% range) body mass index was 34 kg/m² (30-44) and 33 kg/m² (30-41) in patients allocated to the 80% and 30% oxygen group. SSI occurred in 32 of 102 (31%) versus 29 of 111 (26%) patients given 80% and 30% oxygen, respectively (odds ratio, 1.29; 95% CI, 0.71-2.34; P = 0.40). In addition, the incidence of pulmonary complications was not significantly different, with atelectasis occurring in 9% versus 6%, pneumonia in 6% versus 5%, and respiratory failure in 8% versus 5% in patients given 80% and 30% oxygen, respectively. Conclusion Administration of 80% oxygen, compared with 30% oxygen, did not reduce the frequency of SSI in obese patients. Moreover, no significant association was found between oxygen fraction and the risk of pulmonary complications.
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Ghannam, Abdelilah, Abdellah Tazi, Jaouad Tadili, Mamoun Faroudy, and Ali Kettani. "Myasthenia Revealed Following Laparotomy - A Case Report." International Journal of Medicine and Surgery 2, no. 1 (June 30, 2015): 23–25. http://dx.doi.org/10.15342/ijms.v2i1.16.

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Myasthenia (muscle weakness) is a rare neuromuscular disease of which respiratory failure is the main complication. The accidental discovery of such disease in the perioperative period is rare and potentially serious. We report a case of a woman who underwent emergency operation for appendiceal peritonitis, and failed repeatedly at weaning from postoperative mechanical ventilation. The usual etiologies such as postoperative respiratory complications, ventilator-associated pneumonia, acute respiratory distress syndrome complicating the septic shock or having no impact on it, and neuromyopathy’s resuscitation were considered, researched, examined or eliminated. Faced with the diagnostic impasse and the obvious weaning failure, another interview revealed signs of muscle fatigue which led to the diagnosis of myasthenia gravis decompensated perioperatively. Once the diagnosis was confirmed by means of a neostigmine test, the specific treatment began, particularly through plasma exchange sessions, and the process of weaning resumed. The result was complete weaning. A three-month follow-up showed a stable patient with no significant muscular disability.
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