Academic literature on the topic 'Receptors fibroblast growth factor'

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Journal articles on the topic "Receptors fibroblast growth factor"

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Chen, Gregory, and Reza Forough. "Fibroblast Growth Factors, Fibroblast Growth Factor Receptors, Diseases, and Drugs." Recent Patents on Cardiovascular Drug Discovery 1, no. 2 (2006): 211–24. http://dx.doi.org/10.2174/157489006777442478.

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Li, Y., C. Basilico, and A. Mansukhani. "Cell transformation by fibroblast growth factors can be suppressed by truncated fibroblast growth factor receptors." Molecular and Cellular Biology 14, no. 11 (1994): 7660–69. http://dx.doi.org/10.1128/mcb.14.11.7660.

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Ligand-induced dimerization and transphosphorylation are thought to be important events by which receptor tyrosine kinases generate cellular signals. We have investigated the ability of signalling-defective, truncated fibroblast growth factor (FGF) receptors (FGFR-1 and FGFR-2) to block the FGF response in cells that express both types of endogenous FGF receptors. When these dominant negative receptors are expressed in NIH 3T3 cells transformed by the secreted FGF-4, the transformed properties of the cells can be reverted to various degrees, with better reversion phenotype correlating with hig
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Li, Y., C. Basilico, and A. Mansukhani. "Cell transformation by fibroblast growth factors can be suppressed by truncated fibroblast growth factor receptors." Molecular and Cellular Biology 14, no. 11 (1994): 7660–69. http://dx.doi.org/10.1128/mcb.14.11.7660-7669.1994.

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Ligand-induced dimerization and transphosphorylation are thought to be important events by which receptor tyrosine kinases generate cellular signals. We have investigated the ability of signalling-defective, truncated fibroblast growth factor (FGF) receptors (FGFR-1 and FGFR-2) to block the FGF response in cells that express both types of endogenous FGF receptors. When these dominant negative receptors are expressed in NIH 3T3 cells transformed by the secreted FGF-4, the transformed properties of the cells can be reverted to various degrees, with better reversion phenotype correlating with hig
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Wang, Shuwei, and Zhongyang Ding. "Fibroblast growth factor receptors in breast cancer." Tumor Biology 39, no. 5 (2017): 101042831769837. http://dx.doi.org/10.1177/1010428317698370.

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Fibroblast growth factor receptors are growth factor receptor tyrosine kinases, exerting their roles in embryogenesis, tissue homeostasis, and development of breast cancer. Recent genetic studies have identified some subtypes of fibroblast growth factor receptors as strong genetic loci associated with breast cancer. In this article, we review the recent epidemiological findings and experiment results of fibroblast growth factor receptors in breast cancer. First, we summarized the structure and physiological function of fibroblast growth factor receptors in humans. Then, we discussed the common
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Green, Paula J., Frank S. Walsh, and Patrick Doherty. "Promiscuity of fibroblast growth factor receptors." BioEssays 18, no. 8 (1996): 639–46. http://dx.doi.org/10.1002/bies.950180807.

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Hsu, Pi-en, Fu Yu, François Féron, James O. Pickles, Kyra Sneesby, and Alan Mackay-Sim. "Basic fibroblast growth factor and fibroblast growth factor receptors in adult olfactory epithelium." Brain Research 896, no. 1-2 (2001): 188–97. http://dx.doi.org/10.1016/s0006-8993(01)02173-4.

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Galzie, Zoya, Anne R. Kinsella, and John A. Smith. "Fibroblast growth factors and their receptors." Biochemistry and Cell Biology 75, no. 6 (1997): 669–85. http://dx.doi.org/10.1139/o97-091.

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Fibroblast growth factors (FGFs) represent a group of polypeptide mitogens eliciting a wide variety of responses depending upon the target cell type. The knowledge of the cell surface receptors mediating the effects of FGFs has recently expanded remarkably. The complexity of the FGF family and the FGF-induced responses is reflected in the diversity and redundancy of the FGF receptors. In this review, a number of biochemical characteristics and biological properties of the FGF family and its receptors are described and their expression both in normal tissues and in tumours is discussed. Finally
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Malot, Michel, Edith Browaeys-Poly, Franck Foumiertjt, Katia Cailliaul, and Jean Pierre Vilain. "Ca2+Oscillations induced by fibroblast growth factor 2 inXenopusoocytes expressing fibroblast growth factor receptors." Molecular Membrane Biology 14, no. 4 (1997): 205–10. http://dx.doi.org/10.3109/09687689709048183.

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Klint, Peter. "Signal transduction by fibroblast growth factor receptors." Frontiers in Bioscience 4, no. 1-3 (1999): d165. http://dx.doi.org/10.2741/klint.

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Fedyanin, M. Yu, D. N. Hmel’kova, T. S. Serebriyskaya, T. A. Nikol’skaya, and S. A. Tyulyandin. "Fibroblast growth factor receptors in malignant tumors." Malignant tumours, no. 4 (May 21, 2015): 19. http://dx.doi.org/10.18027/2224-5057-2014-4-19-34.

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Dissertations / Theses on the topic "Receptors fibroblast growth factor"

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Petiot, Anita Claire. "Fibroblast growth factor receptors and skeletogenesis." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368708.

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Markert, Anja. "Fibroblast growth factor receptors in chemoresistance." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/39292.

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Chemoresistance is a major obstacle to successful treatment in many cancers. Identification and dissection of the mechanisms underlying chemoresistance is therefore crucial for finding new therapeutic targets to improve patient survival. One growth factor implicated in chemoresistance is FGF2. It has been shown to be involved in triggering chemoresistance in small cell lung cancer (SCLC) and osteosarcoma cells via the activation of a MAPK-dependent signalling pathway. Similarly, previous work by our group has shown that FGF10 induces chemoresistance in SCLC. Here, we investigated whether FGF2
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Grand, Effie Kyriacou. "Deregulated fibroblast growth factor receptors in haematological malignancies." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419978.

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Burgar, Helen Rachel. "Fibroblast growth factor receptor signalling." Thesis, University of Birmingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275129.

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Walters, Jean E. "Immunochemical studies on fibroblast growth factor-1 and fibroblast growth factor receptor 1." Thesis, Oxford Brookes University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245703.

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Markham, Hilary Jane. "The role of fibroblast growth factor receptors in mammalian odontogenesis." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272151.

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Britto, Jonathan Anthony. "Syndromic craniofacial dysostosis : from genotype to phenotype: studies of FGFR gene expression in human craniofacial development and craniosynostosis." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268446.

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Drugan, Caroline S. "The role of fibroblast growth factors and their receptors in human oral carcinogenesis." Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389231.

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Kolanczyk, Maria Elzbieta. "Signaling mechanisms and developmental function of fibroblast growth factor receptors in zebrafish." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:14-ds-1242722157657-12154.

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Fibroblast growth factor (Fgf) signaling plays multiple inductive roles during development of vertebrates (Itoh 2007). Some Fgfs, such as Fgf8, are locally secreted and signal over a long range to provide positional information in the target tissue (Scholpp and Brand 2004). Fgf ligands signal in a receptor-dependent manner via tyrosine kinase receptors, four of which have been so far identified. Fgf8 signaling was shown to depend both on receptor activation as well as endocytosis. The specificity of Fgf ligands and receptors as well as the function of receptors in the control of the Fgf signal
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Powell, Andrew Keith. "Characterisation of the interaction of fibroblast growth factor receptors with heparan sulphate." Thesis, University of Birmingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288866.

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Books on the topic "Receptors fibroblast growth factor"

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Burgar, Helen Rachel. Fibroblast growth factor receptor signalling. University of Birmingham, 2002.

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Walters, Jean Elizabeth. Immunochemical studies on fibroblast growth factor-1 and fibroblast growth factor receptor 1. Oxford Brookes University, 1998.

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Smith, Conrad. Developmental changes in the injury induced expression of fibroblast growth factor-2 and fibroblast growth factor receptor 1 in the rat brain. University of Birmingham, 1998.

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Thompson, Stuart David. Fibroblast growth factor 2 and its receptor, FGFR 1 in the normal thyroid and multinodular goitre. University of Birmingham, 2000.

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1945-, Lippman Marc E., Ortho Pharmaceutical Corporation, and University of California, Los Angeles., eds. Growth regulation of cancer: Proceedings of an Ortho-UCLA Symposium on Growth Regulation of Cancer, held at Park City, Utah, January 17-23, 1987. Liss, 1988.

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Plowright, Elizabeth Emma. Expression of fibroblast growth factor receptor 3 in multiple myeloma causes II-6-independence and enhanced survival. National Library of Canada, 1999.

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Clarke, Wendy Elizabeth. Intracellular compartmentalisation of fibroblast growth factor-2 and associated high and low affinity receptors after cerebral injury to the adult rat brain. University of Birmingham, 1999.

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Onwuazor, Obiageli Nneka. Mutation, SNP and isoform analysis of fibroblast growth factor receptor 3 (FGFR3) in 150 newly diagnosed multiple myeloma patients. National Library of Canada, 2003.

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Cocks, Helen Catherine. Fibroblast growth factor in the thyroid. University of Birmingham, 2003.

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Lyn-Cook, Richard X. Cortical development in fibroblast growth factor 2 knockout mice. s.n.], 1999.

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Book chapters on the topic "Receptors fibroblast growth factor"

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Ornitz, David M., and Gabriel Waksman. "Fibroblast Growth Factor Receptors." In Growth Factors and Wound Healing. Springer New York, 1997. http://dx.doi.org/10.1007/978-1-4612-1876-0_9.

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Burgess, Wilson H. "Structure-Function Analysis of Fibroblast Growth Factor-1 (Acidic Fibroblast Growth Factor)." In Growth Factors, Peptides and Receptors. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2846-3_28.

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Baird, A., and P. Böhlen. "Fibroblast Growth Factors." In Peptide Growth Factors and Their Receptors I. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-49295-2_7.

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Baird, A., and P. Böhlen. "Fibroblast Growth Factors." In Peptide Growth Factors and Their Receptors I. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4612-3210-0_7.

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Quarto, Natalina, Gérard Bouche, Béatrix Bugler, et al. "The Basic Fibroblast Growth Factor Isoforms: Endogenous and Exogenous Behavior." In Growth Factors, Peptides and Receptors. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2846-3_15.

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Cariello, Marica, Marilidia Piglionica, Raffaella Maria Gadaleta, and Antonio Moschetta. "The Enterokine Fibroblast Growth Factor 15/19 in Bile Acid Metabolism." In Bile Acids and Their Receptors. Springer International Publishing, 2019. http://dx.doi.org/10.1007/164_2019_235.

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Baird, A. "Angiogenesis, Fibroblast Growth Factors, and Their Receptors." In Therapeutic Angiogenesis. Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-662-03776-8_1.

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Muenke, Maximilian, Clair A. Francomano, M. Michael Cohen, and Ethylin Wang Jabs. "Fibroblast Growth Factor Receptor-Related Skeletal Disorders." In Principles of Molecular Medicine. Humana Press, 1998. http://dx.doi.org/10.1007/978-1-59259-726-0_114.

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Bridge, Peter J. "Fibroblast Growth Factor Receptor–Related Skeletal Disorders." In Molecular Pathology in Clinical Practice: Genetics. Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-87374-9_9.

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Pike, Kurt G. "Inhibitors of the Fibroblast Growth Factor Receptor." In Topics in Medicinal Chemistry. Springer International Publishing, 2017. http://dx.doi.org/10.1007/7355_2017_13.

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Conference papers on the topic "Receptors fibroblast growth factor"

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Alijaj, Nagjie, Sandrine Moutel, Maxim Gray, et al. "Abstract 3116: Targeting fibroblast growth factor receptors in rhabdomyosarcoma." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-3116.

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Alijaj, Nagjie, Sandrine Moutel, Maxim Gray, et al. "Abstract 3116: Targeting fibroblast growth factor receptors in rhabdomyosarcoma." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-3116.

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Labrecque, Mark P., Lisha G. Brown, Ilsa M. Coleman, et al. "Abstract 1458: Targeting fibroblast growth factor receptors in castration-resistant prostate cancer." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-1458.

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Patel, Nisha S., and Alisa Morss Clyne. "A Computational Model of Fibroblast Growth Factor-2 Binding to Isolated and Intact Cell Surface Receptors: Effects of Fibroblast Growth Factor-2 Concentration, Flow and Delivery Mode." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80798.

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Fibroblast growth factor-2 (FGF2) plays an important role in both healthy vascular cell functions and pathogenesis in cancer, atherosclerosis and reduced perfusion in diabetes (1–4). FGF2 therapy and targeted drug delivery have great potential in the treatment of such diseases, but have had little clinical success. FGF2 binding kinetics to heparan sulfate proteoglycan (HSPG) and fibroblast growth factor receptors (FGFR) have been largely studied under static conditions (5), however FGF2 binding to endothelial cells occurs physiologically under fluid flow conditions. Understanding complex FGF2
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Shimada, Yutaka, Tomoyuki Okumura, Takuya Nagata, Yoshinori Takei, Kazuhiro Tsukada, and Kazuharu Shimizu. "Abstract 3447: Role of fibroblast growth factor receptors in esophageal squamous cell carcinoma." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3447.

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Tokunaga, Ryuma, Yu Imamura, Kenichi Nakamura, et al. "Abstract 568: Fibroblast growth factor receptors 2 is a novel therapeutic target in esophagogastric junction adenocarcinoma." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-568.

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Naito, Zenya, Yoko Matsuda, Yoko Kawamoto, et al. "Abstract 285: Fibroblast growth factor receptor 2IIIc enhances the growth of colorectal adenocarcinoma cells." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-285.

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Feng, Shu, Wendong Yu, Yi Cai, Jianghua Wang, and Michael M. Ittmann. "Abstract 3271: Targeting fibroblast growth factor receptor 4 decreases prostate cancer growth and metastasis." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-3271.

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Paur, Jakob, Lisa Nika, Christiane Maier, et al. "Abstract 1671: Fibroblast growth factor receptor 3 enhances progression of hepatocellular carcinoma." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-1671.

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Epstein Shochet, G., E. Brook, E. Edelstein, et al. "Nintedanib Blocks the IPF-Fibroblast Paracrine Induction of Epidermal Growth Factor Receptor." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5321.

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Reports on the topic "Receptors fibroblast growth factor"

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Ittmann, Michael M. Fibroblast Growth Factor Receptor-4 and Prostate Cancer Progression. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada446482.

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Ittmann, Michael M. Fibroblast Growth Factor Receptor-4 and Prostate Cancer Progression. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada462818.

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Ittmann, Michael M. Fibroblast Growth Factor Receptor-4 and Prostate Cancer Progression. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada476956.

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Ozen, Mustafa. Disruption of Fibroblast Growth Factor Receptor (FGFR) Signaling as an Approach to Prostate Cancer Therapy. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada443202.

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Ozen, Mustafa. Disruption of Fibroblast Growth Factor Receptor (FGFR) Signaling as an Approach to Prostate Cancer Therapy. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada455329.

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Ozen, Mustafa. Disruption of Fibroblast Growth Factor Receptor (FGFR) Signaling as an Approach to Prostate Cancer Therapy. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada427152.

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Welling, Bradley. Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada591173.

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Reiss, Michael. Transforming Growth Factor-B Receptors in Humans. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada393526.

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Kagan, Benjamin L. Growth Factor Regulation of an Angiogenic Factor, the Fibroblast Growth Factor-Binding Protein (FGF-BP), in Breast Cancer. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada398106.

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Kagan, Benjamin L. Growth Factor Regulation of an Angiogenic Factor, the Fibroblast Growth Factor-Binding Protein (FGF-BP), in Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada410065.

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