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Journal articles on the topic 'Surgical Excision Recurrences Radiotherapy'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Tonev, Ivan Dimitrov, Yana Stoeva Pirgova, and Nikolay Vladimirov Conev. "Primary Adenoid Cystic Carcinoma of the Skin with Multiple Local Recurrences." Case Reports in Oncology 8, no. 2 (2015): 251–55. http://dx.doi.org/10.1159/000431082.

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Primary adenoid cystic carcinoma (PACC) of the skin is a rare tumor with fewer than 70 cases studied in detail in the English literature. This type of tumor shows a prolonged course and a growth pattern usually manifested by multiple local recurrences and has a low potential for distant metastases. The most important modality for primary treatment is surgical resection followed by radiotherapy. We report a woman aged 43 years at the time of diagnosis, who presented with a slow-growing nodule in the right axilla without lymph node enlargement. A wide local excision was performed, and the histol

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Maharaj, Daya, and Carlos M. C. Fernandes. "Surgical Experience with Juvenile Nasopharyngeal Angiofibroma." Annals of Otology, Rhinology & Laryngology 98, no. 4 (1989): 269–72. http://dx.doi.org/10.1177/000348948909800406.

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Our experience with 18 cases of juvenile nasopharyngeal angiofibroma (jna) over a period of 9 years is discussed. All cases were managed surgically: 17 via a transpalatal approach and one case by a combined transpalatal, lateral rhinotomy, and transantral approach. In this series there were two recurrences following primary surgical procedures and these required a second procedure. There were no major complications and all 18 patients are alive. We believe that surgical excision should be the treatment of choice for jna and that radiotherapy should be used adjunctively for cases wherein intrac

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Wijeratne, YMTY, HDKC Hapuachchige, and S. Kannangara. "A Rare Case Series of Vaginal Melanoma- experience of National Cancer Institute Sri Lanka." Asian Pacific Journal of Cancer Care 7, no. 2 (2022): 409–13. http://dx.doi.org/10.31557/apjcc.2022.7.2.409-413.

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Vaginal melanomas are extremely rare gynaecological malignancy with aggressive behavior resulting in poor outcome. The aetiology is not well understood so far. There is no standardized treatment owing to the extreme rarity of the disease, however surgical excision with adjuvant radiotherapy has been the widely practiced treatment. The role of lymphadenectomy is controversial. The six cases reported between November 2015 to November 2021 at the National cancer institute Sri Lanka were treated primarily by surgical excision including hysterocolpectomy, colpectomy, and wide local excision. Pelvic

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Tsai, Sheng-Lin, Yu-Chi Tsai, Yu-Tse Weng, Wen-Yen Huang, and Chih-Hsin Wang. "Keloid Excision With Primary Closure Combined With Superficial Radiation Therapy (SRT-100)." Annals of Plastic Surgery 94, no. 3S (2025): S18—S23. https://doi.org/10.1097/sap.0000000000004187.

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Background Surgery plus radiotherapy is associated with fewer recurrences after keloid treatment. However, the side effects of radiotherapy are of concern. Superficial radiation therapy has a low energy, targets the skin, and spares deeper structures, making it ideal for keloid treatment. Many studies have reported good outcomes after surgery combined with superficial radiation therapy. This study provided data on Taiwanese patients who underwent keloid excision with simple primary closure and superficial radiation therapy. Methods We retrospectively collected data from patients who underwent

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Lee, Jeong Won, and Ki Ho Seol. "Adjuvant Radiotherapy after Surgical Excision in Keloids." Medicina 57, no. 7 (2021): 730. http://dx.doi.org/10.3390/medicina57070730.

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Keloids are a benign fibroproliferative disease with a high tendency of recurrence. Keloids cause functional impairment, disfigurement, pruritus, and low quality of life. Many therapeutic options have been used for keloids. However, the high recurrence rates have led to the use of adjuvant therapy after surgical keloid excision. There are different radiotherapy regimens available, and the advantages and disadvantages of each are still unclear. The aim of this review is to explain the appropriate radiotherapy regimen for keloids as well as discuss the recent reports on keloid management with ra

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Acar, Ömer, and Öner Şanlı. "Surgical Management of Local Recurrences of Renal Cell Carcinoma." Surgery Research and Practice 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/2394942.

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Surgical resection either in the form of radical nephrectomy or in the form of partial nephrectomy represents the mainstay options in the treatment of kidney cancer. In most instances, resecting the tumor bearing kidney or the tumor itself provides durable cancer specific survival rates. However, recurrences may rarely develop in the renal fossa or remnant kidney. Despite its rarity, locally recurrent RCC is a challenging condition in terms of the possible management options and relatively poor prognosis. If technically feasible, wide surgical excision and ensuring negative surgical margins ar

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Karadağ, İbrahim, Özgür Koçak, Fatih Şahin, Güven Güney, and Serdar Karakaya. "A case of unilateral ovarian fibrothecoma and pelvic aggressive angiomyxoma with a concurrent diagnosis." Injector 3, no. 1 (2024): 34–38. https://doi.org/10.5281/zenodo.11200318.

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Aggressive angiomyxoma (AA) is a rare mesenchymal tumor that is more common in women and can cause local recurrences, usually originating from the pelvis. Surgical excision is the main treatment method. In patients who cannot be completely excised or who relapse, hormone therapy and radiotherapy can be other options. A rare subtype of ovarian sex-cord stromal tumor is called fibrothecoma (FT). Early diagnosis is common and surgical excision is typically enough for treatment. In this report, we describe the case of a 56-year-old woman who was simultaneously diagnosed with two distinct cancers.

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Kathuria, Sunil, and Chikku Sunny. "Olfactory neuroblastoma: A case report." IP Indian Journal of Anatomy and Surgery of Head, Neck and Brain 8, no. 1 (2022): 19–22. http://dx.doi.org/10.18231/j.ijashnb.2022.006.

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Olfactory neuroblastoma (ON) is a rare malignant neuroectodermal tumor of the nasal cavity. The malignancy accounts for &#60;3% of tumours originating in the nasal cavity. Through the nasal cavity, ON may infiltrate the sinuses, the orbit and the cranium. The tumour is characterized by a pattern of slow growth and local recurrences. Olfactory neuroblastoma is a neoplasm that can histologically mimic many tumours within the sinonasal tract. Treatment options are surgical excision combined with a radiotherapy and/or chemotherapy combination treatment.The present study reports the case of a 4

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Pari, Vishnupriya, Biswanath Roy, Surajit Gorai, Saptarshi Bhattacharya, Tanweer Shahid, and Ritu Srivastava. "Multiple cutaneous squamous cell carcinoma of the forehead in a patient with skin of color treated by wide local excision with adjuvant radiotherapy: a case report." International Journal of Otorhinolaryngology and Head and Neck Surgery 10, no. 3 (2024): 358–61. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20241339.

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Cutaneous squamous cell carcinoma is the second most common non-melanoma skin cancer, characterized by the proliferation of keratinocytes, with an increasing incidence worldwide. In cases of perineural invasion, surgical excision followed by adjuvant radiotherapy is the preferred treatment. An intraoperative frozen section is necessary to determine the cancer-cell-free margin. A 80-year-old male presented to the outpatient department of our hospital with two fungating growths over his right forehead (size 2.7×1.2 cm) and right temple region (size 4×1.2 cm) for 5 years. An incisional biopsy of

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Ogawa, Rei, Mamiko Tosa, Teruyuki Dohi, Satoshi Akaishi, and Shigehiko Kuribayashi. "Surgical excision and postoperative radiotherapy for keloids." Scars, Burns & Healing 5 (January 2019): 205951311989111. http://dx.doi.org/10.1177/2059513119891113.

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Keloids can be treated in a number of ways, including by surgery. Multiple studies now show that while surgical monotherapy associates with extremely high rates of recurrence (50%–80%), postoperative radiotherapy can significantly reduce these recurrence rates. Ongoing improvements in radiation technology have further increased the safety and efficacy of this combination protocol. Of the various radiotherapies that have been used in this setting, electron beam (β-ray) irradiation is currently the best due to its excellent dose distribution and safety. The maximal biologically effective dose (B

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Benabdallah, Y. Staouni, S. Sidki, G. Fallouh, R. Al Sabbagh, and R. Aboutaeib. "The Liposarcoma of the Spermatic Cord: A Rare Tumor." Scholars Journal of Medical Case Reports 12, no. 02 (2024): 235–38. http://dx.doi.org/10.36347/sjmcr.2024.v12i02.026.

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Liposarcoma of the spermatic cord is a rare tumor, with only 60 cases reported in the literature, constituting 7% of malignant tumors of the spermatic cord. We present a new case of an unusual liposarcoma of the spermatic cord, characterized by its necrotic and myxoid variant, occurring in a 66-year-old man in good general health. The primary treatment involves the widest possible surgical excision, with adjuvant radiotherapy sometimes proving effective against local recurrences. Despite its slow progression, extended surveillance is necessary due to the high risk of late recurrence.

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Chandra, P. S., B. S. Sharma, and Manmohan Singh. "Aggressive surgical management of craniopharyngiomas." Indian Journal of Neurosurgery 02, no. 02 (2013): 138–41. http://dx.doi.org/10.4103/2277-9167.118113.

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Abstract Surgical treatment of craniopharyngiomas is challenging and despite advancements it continues to pose a challenge. Proponents of subtotal resection in conjunction with radiotherapy argue that this less aggressive approach can yield appropriate results with the lower morbidity. On the contrary, other argument is that gross total resection is superior. Though surgical management of craniopharyngioma is challenging due to its location and important surrounding neurovascular structures, optimal surgical results can be expected following radical surgical excision. Radical excision of crani

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Sherriff, Jennifer, Urmila Barthakur, Paul Sanghera, et al. "Post-operative accelerated hypofractionated radiotherapy for adenoid cystic carcinoma." Journal of Radiotherapy in Practice 10, no. 2 (2010): 85–90. http://dx.doi.org/10.1017/s1460396910000178.

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AbstractObjective: To examine the outcomes of patients with adenoid cystic carcinoma (ACC) treated with post-operative accelerated hypofractionated radiotherapy (AHRT).Methods: Patients treated with AHRT (50–55 Gy in 20 fractions over 25 days) between 1997 and 2008 were identified and retrospectively analysed. Data collection included site of primary and surgical excision margin. Primary outcomes were overall survival (OS) and local control (LC) calculated using the Kaplan–Meier method.Results: A total of 37 patients meeting the above criteria were identified with a median age of 55 years (ran

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Adil, Dehhaze, Mai Aicha, Barij Hamza, et al. "Dermatofibrosarcoma of Darrier and Ferrand: Recurrency Character: A Case-Report (Experience of the University Hospital Tangier-Tetouan-Al Hoceima)." Scholars Journal of Medical Case Reports 12, no. 04 (2024): 610–14. http://dx.doi.org/10.36347/sjmcr.2024.v12i05.009.

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Introduction: Dermatofibrosarcoma of Darier and Ferrand (DFSP) is a rare skin tumor characterized by its local aggressiveness and high potential. Its prognosis depends essentially on the quality of its management. Observation and Results: In this article, we report the case of a young patient treated at the Department of Plastic, Reconstructive and Aesthetic Surgery, Tangier, for a Darier and Ferrand dermatofibrosarcoma that recurred five times after surgical excision, with a 5-cm margin on the surface and a healthy anatomical barrier at depth. Coverage of the loss of substance (LOS) was perfo

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Martin, Luke, Miguel S. Cabalag, Anand Ramakrishnan, and Andrew Martin. "Management of close/positive margins in cutaneous squamous cell carcinoma of the head and neck: a systematised review." Australasian Journal of Plastic Surgery 7, no. 2 (2024): 1–13. http://dx.doi.org/10.34239/ajops.88849.

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Introduction: The authors reviewed close/positive margins in cutaneous squamous cell carcinoma of the head and neck, ensuing recurrence, regional or systemic metastasis, mortality and follow-up management. Methods: The design was a systematised review from January 2000 to July 2021. The MEDLINE database was searched with 15 articles out of 3104 meeting the inclusion criteria. Pertinent references underpinning the National Comprehensive Cancer Network’s Squamous Cell Skin Cancer Guidelines Version 2.2022 were reviewed. Results: Overall, there were 13,671 cutaneous squamous cell carcinoma lesion

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Toffoli, Ludovica, Giulia Bazzacco, Claudio Conforti, et al. "Pilomatrix Carcinoma: Report of Two Cases of the Head and Review of the Literature." Current Oncology 30, no. 2 (2023): 1426–38. http://dx.doi.org/10.3390/curroncol30020109.

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Background: Pilomatrix carcinoma (PC) is a rare skin tumor arising from hair follicle matrix cells. It is locally aggressive with a high rate of local recurrence after surgical excision. Few cases in the literature have been described and the management is not well defined. Objectives: The aim of this study was to present two cases of PC located on the head and review the relevant literature about epidemiology, clinical and dermoscopic evaluation, characteristics of local and distant metastases, local recurrence rate and management of this rare skin tumor. Methods: We consulted databases from

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Lee, Justin, Ian Poon, Judith Balogh, May Tsao, and Elizabeth Barnes. "A Review of Radiotherapy for Merkel Cell Carcinoma of the Head and Neck." Journal of Skin Cancer 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/563829.

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Merkel cell carcinoma of the head and neck (MCCHN) presents a clinical challenge due to its aggressive natural history, unpredictable lymphatic drainage, and high degree of treatment related morbidity. Histological examination of the regional lymph nodes is very important in determining the optimal treatment and is usually achieved by sentinel lymph node biopsy. Radiotherapy plays a critical role in the treatment of most patients with MCCHN. Surgery with adjuvant radiotherapy to the primary tumour site is associated with high local control rates. If lymph nodes are clinically or microscopicall

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Duinkerken, Charlotte W., Peter J. F. M. Lohuis, Marianne B. Crijns, et al. "Orthovoltage X-rays for Postoperative Treatment of Resected Basal Cell Carcinoma in the Head and Neck Area." Journal of Cutaneous Medicine and Surgery 21, no. 3 (2016): 243–49. http://dx.doi.org/10.1177/1203475416687268.

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Background: Surgery is the golden standard for treating basal cell carcinomas. In case of positive tumor margins or recurrent disease, postoperative adjuvant or salvaging therapy is suggested to achieve good local control. Objective: To retrospectively report on local control and toxicity of postoperative radiotherapy by means of orthovoltage X-rays for residual or recurrent basal cell carcinoma after surgery in the head and neck area. Methods: Sixty-six surgically resected residual or recurrent basal cell carcinomas of the head and neck region were irradiated postoperatively by means of ortho

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Turcu, E. G. "Surgical Treatment Option in a Recurrent Giant Sacrococcygeal and Gluteal Squamous Cell Carcinoma - Case Presentation." INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND BIO-MEDICAL SCIENCE 04, no. 07 (2024): 614–17. https://doi.org/10.5281/zenodo.12771696.

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This article refers to the case of a 57-year-old female patient admitted in our clinic for a recurrent giant sacrococcygeal and gluteal squamous cell carcinoma.In the past, excisional biopsy was performed in another clinic of plastic surgery, followed by tumor excision,chemotherapy and radiotherapy for 6 months.After one year, the patient addresses our clinic for giant tumor recurrence in the sacrococcian region and bilateral buttocks. The MRI examination carried out highlights a tumor formation that invades both gluteal regions up to the level of the piriformis muscle and the sacrum. No metas

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Lukovic, Jelena, and Kathy Han. "Postoperative management of vulvar cancer." International Journal of Gynecologic Cancer 32, no. 3 (2022): 338–43. http://dx.doi.org/10.1136/ijgc-2021-002463.

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The primary treatment for resectable vulvar cancer includes wide local excision of the primary tumor and surgical lymph node assessment. Following surgery, up to 40–50% of patients develop a local recurrence. Historically, the strongest predictor of local recurrence is a positive or close margin (defined as <8 mm), although recent studies question the importance of margin status. Post-operative radiotherapy to the vulva is recommended for all women with a positive margin where re-excision is not possible. Radiotherapy may also be considered in the setting of risk factors for local recurrenc

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Sharma, Jyoti, and Lalit Chandrakant. "Oligometastatic recurrence in radically treated stage II lower thoracic ca oesophagus at two drain sites: a treatment challenge?" International Surgery Journal 8, no. 3 (2021): 1060. http://dx.doi.org/10.18203/2349-2902.isj20210952.

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Ca oesophagus is a dreaded malignancy with less than 15 % cure rate and majority of the patients presenting with advanced unresectable disease. Prognosis remains poor despite advances in combined modality treatments. Most common sites of loco-regional recurrence after surgery remains the mediastinal lymph node clearance area while other common sites are lung liver and bone. Unexpected sites of metastasis have been reported like skin, muscle, eyes etc. We report a case of 66-year-old male patient diagnosed with stage II poorly differentiated squamous cell carcinoma lower oesophagus radically tr

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Murty, George E., Joseph P. Diver, and Patrick J. Bradley. "Carcinoma in Situ of the Glottis: Radiotherapy or Excision Biopsy?" Annals of Otology, Rhinology & Laryngology 102, no. 8 (1993): 592–95. http://dx.doi.org/10.1177/000348949310200804.

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Excision biopsy, radiotherapy, and laryngofissure cordectomy have all been used, but the best treatment regimen for glottic carcinoma in situ remains controversial. A 20-year experience of 37 cases is reported. For the first 10 years biopsy with radiotherapy was the first-line treatment (n = 20), but for the last 10 years surgical or laser excision biopsy alone has been performed (n = 17). The T stage of the carcinoma in situ does not determine its premalignant potential. Malignancy appears to be a recurrence, rather than a new expression of carcinogenesis. Excision biopsy alone provides local

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Parashurama, Raghava, Vivek Nama, and Richard Hutson. "Paget’s Disease of the Vulva: A Review of 20 Years’ Experience." International Journal of Gynecologic Cancer 27, no. 4 (2017): 791–93. http://dx.doi.org/10.1097/igc.0000000000000901.

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BackgroundExtramammary Paget’s disease is a rare condition, and the vulva is a common site for it to occur. Despite this, there is a paucity of literature on Paget’s disease of the vulva (VPD). A Cochrane meta-analysis could not draw any conclusions on interventions in VPD. Our aim was to review our practice and improve further management of VPD in our center.MethodsWe reviewed all the cases presented to Leeds Gynaecological Oncology Centre between 1988 and 2016. All cases identified in this interval were followed up until April 2016. All case notes and electronic patient data were retrieved t

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Todorovic, Dusan, Tatjana Sarenac Vulovic, Suncica Sreckovic, Svetlana Jovanovic, Katarina Janicijevic, and Zeljko Todorovic. "Updates on the Treatment of Pterygium." Serbian Journal of Experimental and Clinical Research 17, no. 3 (2016): 257–62. http://dx.doi.org/10.1515/sjecr-2016-0012.

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AbstractPterygium is an ocular disease characterised by the growth of fibrovascular conjunctiva on the cornea. It occurs more often in men, at an older age, and in individuals exposed to ultraviolet radiation. Surgical treatment is the primary treatment for pterygium and there are two common procedures for pterygium excision. In the first method, the head of the pterygium is separated from the corneal surface using a surgical blade. The second method is based on avulsion. Other approaches to excising the pterygium include the use of argon laser and excimer laser. Because of a high recurrence r

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Maiti, Mousam, Ajay Mallick, Debangshu Ghosh, and Indranil Chakrabarti. "Adolescent tongue base tumour with diagnostic histopathological dilemma." BMJ Case Reports 17, no. 8 (2024): e259570. http://dx.doi.org/10.1136/bcr-2023-259570.

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Mucoepidermoid carcinoma arising from minor salivary glands at the base of the tongue is rare. Surgical excision of the tumours remains the primary treatment of choice. The prognosis of this tumour depends on optimum clearance of the disease surgically, clinical staging and histopathological grading. Postoperatively, radiotherapy depends on the grading and histopathological features of the tumour. Long-term follow-up is a must to detect early recurrences of oropharyngeal tumours. In our case, the tumour was removed by the transoral route because it was a limited tumour and for better postopera

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Mucha-Małecka, A., K. Urbanek, A. Ambicka, P. Majchrzak, and K. Małecki. "Radiotherapy in lymphoepithelioma-like carcinoma of the skin: review of the literature and report of a recurrent and metastatic case." Strahlentherapie und Onkologie 195, no. 11 (2019): 1028–32. http://dx.doi.org/10.1007/s00066-019-01516-8.

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Abstract Primary lymphoepithelioma-like carcinoma of the skin (LELCS) is a very rare cutaneous neoplasm. Only about 70 cases have been documented in the literature. There are no prospective data regarding treatment methods. Surgical excision is sufficient therapy in the majority of cases. Radiation therapy is sometimes used in case of recurrence or positive margins after surgery. The metastatic potential of LELCS is extremely low and only five previously documented cases of lymph node spread have been reported. We present the case of an 80-year-old male with a tumor primarily located on the lo

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Balakrishnan, V., S. Berry, B. Stew, and A. Sizeland. "Benefits of combined modality treatment of Merkel cell carcinoma of the head and neck: single institution experience." Journal of Laryngology & Otology 127, no. 9 (2013): 908–16. http://dx.doi.org/10.1017/s0022215113001862.

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AbstractBackground:There is ongoing debate surrounding the roles of surgery and adjuvant radiotherapy in the management of primary and recurrent Merkel cell carcinoma of the head and neck. This study assessed the influence of local excision, margin status, adjuvant radiotherapy and chemotherapy on locoregional recurrence and survival.Method:A retrospective review of 54 consecutive cases of head and neck Merkel cell carcinoma at a single institution.Results:Median disease-specific survival time was 120 months. Forty-four per cent of patients developed locoregional recurrence. Combined treatment

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Wang, Ru, Patricia L. Danielsen, Magnus S. Ågren, et al. "Corticosteroid Injection Alone or Combined with Surgical Excision of Keloids versus Other Therapies Including Ionising Radiotherapy: A Systematic Review and Meta-Analysis of Randomised Controlled Trials." European Burn Journal 2, no. 2 (2021): 41–54. http://dx.doi.org/10.3390/ebj2020004.

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Keloid scars are difficult to manage and remain a therapeutic challenge. Corticosteroid therapy alone or ionising radiation (radiotherapy) alone or combined with surgery are first-line treatments, but the scientific justification for these treatments is unclear. The aim of this systematic review and meta-analysis of randomised controlled trials (RCTs) is to assess the effects of intralesional corticosteroid injection in treating keloids or preventing their recurrence after surgical removal. Searches for RCTs were conducted through the MEDLINE, EMBASE, EBSCO and Cochrane databases from January

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Yamanouchi, Daisuke, Toshiyuki Oshitari, Yosuke Nakamura, et al. "Primary Neuroendocrine Carcinoma of Ocular Adnexa." Case Reports in Ophthalmological Medicine 2013 (2013): 1–4. http://dx.doi.org/10.1155/2013/281351.

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We present our findings in a case of primary neuroendocrine carcinoma (NEC) of the lacrimal gland and a case of primary Merkel cell carcinoma (MCC) of the eyelid. An 86-year-old man noticed a swelling of the left upper eyelid three months earlier. We performed excision biopsy and histopathological examination indicated that he had a primary NEC of the left lacrimal gland. He underwent chemotherapy followed by excision including the clinically visible margins and 50 Gy radiotherapy of the surgical margins. He had neither recurrence nor metastasis for 6 months since the last radiotherapy. An 80-

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Vijitha, Vempuluru Sai, Anasua Ganguly Kapoor, Ruchi Mittal, and Ramakrishna Vangara. "Preoperative embolisation of orbital solitary fibrous tumour." BMJ Case Reports 13, no. 12 (2020): e235576. http://dx.doi.org/10.1136/bcr-2020-235576.

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Solitary fibrous tumours (SFT) is an encompassing terminology comprising of tumours with proliferating CD34 positive specialised fibroblasts. Orbital SFTs are rare slowly progressive highly vascular neoplasms. Complete surgical excision is considered the mainstay treatment. Incomplete resection is a known risk factor for recurrence and malignant transformation. Recently preoperative embolisation of SFT has shown promising results in reducing the vascularity of these tumours rendering them amenable to complete surgical excision. Less than 10 cases of embolisation of orbital solitary fibrous tum

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Graves, Glenn M., Dale E. Bjorling, and Edward Mahaffey. "Canine hemangiopericytoma: 23 cases (1967-1984)." Journal of the American Veterinary Medical Association 192, no. 1 (1988): 99–102. https://doi.org/10.2460/javma.1988.192.01.99.

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Summary The medical records of 23 histopathologicaily confirmed cases of canine hemangiopericytoma were reviewed. Ninety-one percent (21/23) of the dogs were 7 years old or older, and 70% (16/23) were female. Seventy-four percent (20/27) of the tumors developed on the extremities. Recurrence rates were 31% (5/16) with surgical excision only, and 60% (3/5) with surgical excision combined with radiotherapy. Tumor recurrence did not appear to be related to mitotic index. Metastasis was suspected in one of the dogs, but was not confirmed.

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Kunkiel, Michal, Anna Niwinska, Agnieszka I. Jagiello-Gruszfeld, and Wojciech Michalski. "Validation of the Van Nuys Prognostic Index in 737 patients with ductal carcinoma in situ (DCIS) treated at Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland." Journal of Clinical Oncology 38, no. 15_suppl (2020): e12603-e12603. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e12603.

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e12603 Background: To assess the value of the Van Nuys Prognostic Index (VNPI) used in Maria Sklodowska-Curie National Research Institute of Oncology (MSCNRIO) to select the most adequate method of the treatment of DCIS patients. Methods: The database covered 737 subsequent DCIS patients treated in MSCNRIO in the years 1996 -2011. The results of the treatment with and without compliance with the VNPI index were compared. Results: In the group of 737 patients 66 (9%) failures were reported. There were 4 (0.5%) deaths due to DCIS progression. After 15 years of observation of patients treated in

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Guenzi, Marina, Paola Franzone, Maria Pia Muttini, et al. "Radio-Hyperthermia in Post-Surgical Recurrence of Melanoma." Tumori Journal 79, no. 6 (1993): 410–12. http://dx.doi.org/10.1177/030089169307900608.

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Aims and background Malignant melanoma is one of the most radioresistant tumors. It can be treated with combinated hyperthermia and radiation therapy. Methods From January 1991 through June 1992, 7 patients, 1 male and 6 female, aged 40-88 years (mean 75), with skin and nodal postsurgical recurrences of melanoma, were treated with a combination of radiation therapy and hyperthermia. Two patients presented systemic disease when they reached our observation, but all of them were without symptoms. None of them underwent surgical excision of the recurrence before or during thermoradiotherapy. None

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D C, Sathyaki, and Nalina P A. "Efficacy of Triamcinolone in Treatment of Keloid." Bengal Journal of Otolaryngology and Head Neck Surgery 29, no. 3 (2022): 291–94. http://dx.doi.org/10.47210/bjohns.2021.v29i3.557.

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Introduction Keloids are well known for recurrence. There is no standardized regimen for the treatment of keloids. Many different treatment modalities such as surgical excision, intralesional corticosteroids, radiotherapy, and pressure earrings have been used for keloids. Surgical excision alone may result in recurrence rate of 40%-100%. This study was conducted to evaluate the efficacy of triamcinolone in preventing recurrence of Keloid. Materials and Methods Of the 40 patients who underwent excision of keloid at a tertiary care centre, surgery alone was performed in 20 patients and surgery w

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Ramadhani, Febriana R., and Sonar S. Panigoro. "076. Surgical Management Challenges in Recurrent Kimura Disease: A Case Study of a Rare Disease." JBN (Jurnal Bedah Nasional) 8, no. 2 (2024): 76. http://dx.doi.org/10.24843/jbn.2024.v08.is02.p076.

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Background: Kimura disease (KD) is a rare autoimmune disease characterized by angiolymphoid hyperplasia with eosinophilia, primarily affecting young males of Asian descent. First described in 1948, approximately 200 cases have been reported globally. Despite surgical excision, recurrence is common, posing significant challenges for management. This report details the management challenges of recurrent KD. Case: A 30-years-old male presented with recurrent KD of the right buccal. Histologic examination revealed chronic lymphadenitis and eosinophilia. MRI showed a solid heterogeneous mass in the

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Koufman, James A. "The Endoscopic Management of Early Squamous Carcinoma of the Vocal Cord with the Carbon Dioxide Surgical Laser: Clinical Experience and a Proposed Subclassification." Otolaryngology–Head and Neck Surgery 95, no. 5 (1986): 531–37. http://dx.doi.org/10.1177/019459988609500502.

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Sixteen patients with T1 vocal cord squamous cell carcinoma were treated with endoscopic laser excision during a 4-year period. Laser excision was the initial treatment in 11 patients, and it was used to treat 5 patients who had recurrence after radiotherapy. Postoperatively, 13 (81%) of the 16 patients had normal voices. Two patients with persistent postoperative hoarseness had had anterior commissure lesions and previous radiotherapy; the other patient had a subtotal cordectomy. One patient developed a subsequent new lesion 27 months after the initial laser treatment; he was successfully man

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Raducu, Laura, Cristina Nicoleta Cozma, Andra Elena Balcangiu Stroescu, et al. "A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment." Revista de Chimie 69, no. 2 (2018): 354–57. http://dx.doi.org/10.37358/rc.18.2.6106.

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Merkel cell carcinoma is (MCC) a rare type of skin malignancy that appears as a result of a disorganized multiplication of the Merkel cells and has a high rate of recurrence and metastases even from early stages. We describe the case of an 84-year old women diagnosed with Merkel cell carcinoma of the lower lip. Surgical treatment was realised with tumor excision and reconstruction using advancement flaps. Postoperative cosmetic and functional results were excellent, but invasion of the lateral margins, the patient�s decision of refusing re-excision and delayed radiotherapy lead to a rapid recu

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Nahon-Estève, Sacha, Corine Bertolotto, Alexandra Picard-Gauci, et al. "Small but Challenging Conjunctival Melanoma: New Insights, Paradigms and Future Perspectives." Cancers 13, no. 22 (2021): 5691. http://dx.doi.org/10.3390/cancers13225691.

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Although its incidence has increased over the last decades, conjunctival melanoma (CM) remains a rare but challenging periocular malignancy. While there is currently no recognized standard of care, “no-touch” surgical excision followed by adjuvant treatments is usually recommended. Despite its small size, managing CM is challenging for clinicians. The first challenge is the high risk of tumour local recurrence that occurs in about one third of the patients. The management of locally advanced CM (≥T2) or multiple recurrences may require mutilating surgeries such as orbital exenteration (OE). Th

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Sekar, Raghul, Raja Kalaiarasi, Sivaraman Ganesan, Arun Alexander, and Sunil K. Saxena. "Malignant Chondroid Syringoma With Nose and Paranasal Sinus Extension: A Case Report." Allergy & Rhinology 10 (January 2019): 215265671989336. http://dx.doi.org/10.1177/2152656719893367.

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Chondroid syringoma is a rare, skin appendageal tumor. It is also known as mixed tumor of skin, as it histologically resembles mixed tumor of salivary gland (pleomorphic adenoma). It is most commonly a benign tumor, but a few malignant counterparts have been described in history. It usually presents as a solid, slow-growing, solitary, and painless nodule in the head and neck region. Malignant counterpart is rare and commonly affects trunk and extremities. Early diagnosis and surgery by wide local excision are the most reliable treatments to date. Recurrences are common and hence close follow-u

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Ovchinnikov, Mikhail, Alexander Kluttig, Elke Burger, et al. "Secondary Resections and Survival After Breast-Conserving Surgery in Breast Cancer Patients: A Cancer Registry-Based Cohort Study." Cancers 17, no. 3 (2025): 369. https://doi.org/10.3390/cancers17030369.

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Breast cancer remains the most common malignancy in women, and breast-conserving surgery (BCS) with adjuvant radiotherapy is a standard treatment for early-stage disease. This study assessed the impact of positive surgical margins and secondary surgeries on local recurrence rates and patient outcomes. In this retrospective tumor registry-based study, 24,450 women were eligible for analysis. Of them, 18,082 underwent primary BCS only, 4836 underwent re-excision by BCS, and 1532 underwent re-excision by mastectomy following primary BCS. Our findings indicate that even though re-excision procedur

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Bąk, Anna, Wojciech Smółka, and Jarosław Markowski. "Dermatofibrosarcoma protuberans of left temporal area with mass effect causing stenosis of EAM in 66-year-old patient - case report." Polski Przegląd Otorynolaryngologiczny 11, no. 4 (2022): 1–5. http://dx.doi.org/10.5604/01.3001.0016.1565.

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ABSTRACT INTRODUCTION: Dermatofibrosarcoma protuberans (DFSP) is a locally aggressive cutaneous sarcoma with a low metastasis potential, but a high local recurrence rate. It was first described in 1890 [1]. DFSP grows slowly and may take various forms in clinical trials - it presents both as a firm plaque, subcutaneous fat atrophy and a single or polycyclic tumor. Immunohistochemically DFSP, stains positive for CD34. The gold standard for DFSP treatment is a complete surgical excision with a margin of healthy tissue. Adjuvant therapy includes both radiotherapy and imatinib therapy. CASE REPORT

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Morita, Akio, Laligam N. Sekhar, and Donald C. Wright. "Current Concepts in the Management of Tumors of the Skull Base." Cancer Control 5, no. 2 (1998): 138–49. http://dx.doi.org/10.1177/107327489800500205.

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Background: Due to their involvement with critical neurovascular structures, tumors located in the cranial base present challenges to neurosurgeons and are associated with high morbidity and mortality. Methods: Rates of tumor control, complications, patient outcomes, and recurrences were extracted and summarized from two decades of our surgical and radiological treatment follow-up and review of the medical literature. Results: Recent advances in surgical techniques involving cranial base approaches have made surgical intervention safer and curative resection more likely. In managing benign tum

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Somani, Baral, Kumar Sethy Rajesh, Jena Debasis, Dash Rutayani, and Panda Sarita. "Clinical Profile of Periocular Tumors at a Tertiary Care Center in Southern Odisha." International Journal of Pharmaceutical and Clinical Research 16, no. 6 (2024): 543–47. https://doi.org/10.5281/zenodo.13126837.

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This prospective observational study at MKCG Medical College, Berhampur, Odisha, was conducted from April 2023 to March 2024 to analyze the clinical presentations, treatment modalities, and outcomes of periocular tumors. The study encompassed 28 patients, differentiating between benign and malignant tumors based on histopathological evaluations. Benign tumors, primarily dermoid cysts, were effectively managed with surgical excision, while malignant tumors, including basal cell carcinoma, required combined surgical and radiotherapeutic approaches. The findings indicate that meticulous surgical

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Sahu, Santosh Kumar, Khusubu Parichha, Aniruddh Dash, and Nihar Ranjan Mishra. "Pigmented Villonodular Synovitis of Ankle Joint – A Case Report." Journal of Orthopaedic Case Reports 13, no. 11 (2023): 133–36. http://dx.doi.org/10.13107/jocr.2023.v13.i11.4034.

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Introduction: Pigmented villonodular synovitis (PVNS)is a very uncommon lesion that involves the synovium of joints, tendon sheaths, or bursae. Approximately 2.5% of cases occur around the ankle. PVNS was earlier considered to be a synovial malignancy. Complete surgical excision is curative if bony destruction is not there. Radiotherapy is rarely helpful for residual lesions. Case Report: We share a case report on PVNSof ankle in a 22-yearsold male patient. Clinical diagnosis was confirmed with the help of magnetic resonance imaging and histopathology.A surgical excision with synovectomy was c

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Ormeci, Tugrul, Murat Can Kiremit, Bulent Erkurt, and Aslı Örmeci. "An Unusual Long-Term Survey of a Patient with Widespread Malignant Urachal Tumor, Not Given Chemotherapy or Radiotherapy." Case Reports in Radiology 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/183787.

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The urachus establishes a connection between the dome of the bladder and the umbilicus throughout fetal life. If the urachus does not close completely, malignancy is a potential complication. The primary treatment for malignant urachal tumor is surgical excision. A 61-year-old male patient diagnosed with urachal carcinoma had undergone partial cystectomy 25 years previously. Twenty years later, local recurrence was treated with another partial cystectomy without umbilical remnant excision. Recurrence at the umbilical site was excised 2 years later, but intraperitoneal invasion had occurred, an

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Kikuchi, N., T. Nakashima, J. Fukushima, K. Nariyama, and S. Komune. "Well-differentiated liposarcoma arising in the parapharyngeal space: a case report and review of the literature." Journal of Laryngology & Otology 129, S2 (2015): S86—S90. http://dx.doi.org/10.1017/s0022215114002461.

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AbstractBackground:Liposarcomas rarely occur in the parapharyngeal space and only a few case reports exist. For curative therapy of liposarcoma, surgical excision remains the dominant modality. Although a wide surgical margin is important to prevent local recurrence, wide excision is often difficult in the head and neck region.Case report:We report a case of a 19-year-old female with a well-differentiated liposarcoma arising in the parapharyngeal space. We removed the tumour surgically utilising a cervical–parotid approach. The histological diagnosis was well-differentiated sclerosing liposarc

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Wapnir, Irene, Carol Marquez, Kimberly Stone, et al. "Abstract OT1-09-01: A randomized study comparing surgical excision versus NeOadjuvant Radiotherapy followed by delayed surgical excision of Ductal carcinoma In Situ (NORDIS)." Cancer Research 82, no. 4_Supplement (2022): OT1–09–01—OT1–09–01. http://dx.doi.org/10.1158/1538-7445.sabcs21-ot1-09-01.

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Abstract Lumpectomy and breast radiotherapy (RT) achieve good longterm control of disease in patients diagnosed with ductal carcinoma in situ (DCIS). In the combined analysis of NSABP B-17/B-24 DCIS trials, these treatments were shown to reduce invasive ipsilateral breast tumor recurrences by 52% compared to lumpectomy alone. RT has been consistently used as an adjuvant to surgery and therefore, little is known of its activity on intact/untreated DCIS. Elucidating the effectiveness of radiation therapy may help optimize the treatment of DCIS and avoid over-treatment.Trial Design The objective

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Le, Minh Hang, Thao Luat Huynh, and Minh Khoi Tran. "SURGICAL MANAGEMENT OF GIANT ABDOMINAL LIPOSARCOMA TWO CASE REPORTS." Tạp chí Y Dược học Cần Thơ, no. 8TA (November 25, 2024): 129–34. https://doi.org/10.58490/ctump.2024i8ta.3342.

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Introduction: Abdominal sarcomas, accounting for 15–20% of all sarcomas, are rare and often grow large before causing symptoms, leading to limited reports on the disease. Case presentation: This review discusses two surgical cases: a 13.5 kg retroperitoneal liposarcoma (40 cm) in a 71-year-old male and a 6 kg liposarcoma in the small bowel mesentery in a 46-year-old female. Both patients presented with large abdominal tumors causing compressive symptoms. Contrastenhanced CT scans suggested liposarcoma, and both underwent complete surgical excisions without complications. They were discharged a

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Teng-Chin, Wang. "Polymorphous Low-Grade Adenocarcinoma: A Rare Cause of Long-term Epistaxis." Archives of Otolaryngology and Rhinology 2, no. 1 (2016): 027–29. https://doi.org/10.17352/2455-1759.000018.

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Polymorphous low-grade adenocarcinoma (PLGA) of the paranasal sinus is an extremely rareisease. PLGA is a minor salivary gland neoplasm that occurs mostly in the junction of the soft andhard palate, followed by the buccal mucosa and upper lip. Only a few cases have been reported in the sinonasal area. PLGA  generally follows a benign clinical course with frequent perineural invasion but low metastatic potential We report on a patient with PLGA in the ethmoid sinus, which presented as a nasal polyp withepistaxis for more than 2 years. The patient received surgical excision with adjuvant ra

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Shein, Gregory, Alison J. Potter, Christine Loo, Robert Smee, Ian Jacobson, and Antoinette Anazodo. "Paediatric Laryngeal Synovial Sarcoma: Dilemmas and Decision-Making." Case Reports in Otolaryngology 2024 (April 1, 2024): 1–5. http://dx.doi.org/10.1155/2024/7574240.

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Primary laryngeal synovial sarcoma is a rare head and neck cancer. We describe a case of synovial sarcoma of the larynx in a previously well 9-year-old boy with a one-month history of a progressively enlarging neck lump. He was referred to our institution after incomplete surgical excision of the then undifferentiated neck mass. A partial laryngectomy including wide local excision of the residual mass was performed. An ipsilateral level I-III neck dissection was also performed concurrently. Clear re-excision margins were achieved. The neck nodes were all negative for metastatic disease. Adjuva

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