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1

G, Goetz Christopher, Aminoff Michael J. 1941-, Vinken P. J. 1927-, and Bruyn G. W. 1928-, eds. Systemic diseases. Elsevier Science Publishers, 1998.

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2

Portincasa, Piero, Gema Frühbeck, and Hendrik M. Nathoe, eds. Endocrinology and Systemic Diseases. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-66362-3.

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3

Michael, Greaves, ed. Blood in systemic diseases. Mosby-Wolfe, 1997.

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4

D, Horn Thomas, ed. Dermatopathology in systemic diseases. Oxford University Press, 2001.

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5

Clair, Symmers William St, and Wight D. G. D, eds. Systemic pathology. 3rd ed. Churchill Livingstone, 1994.

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6

Symmers, William St. Clair, 1917- ed., Friedmann I, Wickramasinghe S. N, et al., eds. Systemic pathology. 3rd ed. Churchill Livingstone, 1986.

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7

Wuyts, Wim A., Vincent Cottin, Paolo Spagnolo, and Athol U. Wells, eds. Pulmonary Manifestations of Systemic Diseases. European Respiratory Society, 2019. http://dx.doi.org/10.1183/2312508x.erm8619.

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8

Ohira, Hiromasa, ed. The Liver in Systemic Diseases. Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55790-6.

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9

Wada, Keiji, ed. Neurodegenerative Disorders as Systemic Diseases. Springer Japan, 2015. http://dx.doi.org/10.1007/978-4-431-54541-5.

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10

David, Talley J., ed. Cardiovascular involvement in systemic diseases. Igaku-Shoin, 1997.

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11

Mark, Zelman, ed. Human diseases: A systemic approach. 7th ed. Pearson Education, 2010.

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12

Mulvihill, Mary L. Human diseases: A systemic approach. 3rd ed. Appleton & Lange, 1991.

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13

Roy, Frederick Hampton. Ocular syndromes and systemic diseases. 2nd ed. W.B. Saunders, 1989.

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14

Mulvihill, Mary L. Human diseases: A systemic approach. 2nd ed. Appleton & Lange, 1987.

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15

Rolando, Cimaz, and Lehman Thomas J. A, eds. Pediatrics in systemic autoimmune diseases. Elsevier, 2008.

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16

Stepanov, Alexandr, and Jan Studnicka, eds. Ocular Manifestations of Systemic Diseases. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-58592-0.

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17

L, Mulvihill Mary, ed. Human diseases: A systemic approach. 6th ed. Pearson Prentice Hall, 2006.

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18

E, Wolverton Stephen, and Wilkin Jonathan K, eds. Systemic drugs for skin diseases. Saunders, 1991.

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19

A, Mathey Richard, ed. Pulmonary manifestations of systemic disease. W. B. Saunders, 1989.

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20

B, Robertson William, Becker Anton E, Symmers William St Clair, and Anderson Robert H. 1942-, eds. Systemic pathology. 3rd ed. Churchill Livingstone, 1993.

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21

U, Wells A., and Denton C. P, eds. Pulmonary involvement in systemic autoimmune diseases. Elsevier, 2004.

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22

Amerio, Alberto, Pasquale Coratelli, Vito M. Campese, and Shaul G. Massry, eds. Drugs, Systemic Diseases, and the Kidney. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-8953-8.

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23

Foster, Brogan, and Paul A. Brogan. Systemic diseases. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198738756.003.0004.

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This chapter covers the full spectrum of systemic diseases in paediatric rheumatology including: the systemic vasculitides (HSP, Kawasaki disease, PAN, ANCA-associated vasculitis, Takayasu arteritis, Behçet's disease, cerebral vasculitis, and many others); juvenile SLE; scleroderma; JDM; overlap syndromes; antiphospholipid syndrome; sarcoid; and paediatric uveitis. In addition, it provides updated descriptions and treatment approaches for autoinflammatory diseases, including recently described diseases such as DADA, SAVI, CANDLE, and many others. Other systemic diseases described in detail inc
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24

Foster, Helen, and Paul A. Brogan, eds. Systemic diseases. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199592630.003.0004.

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VasculitisThe classification of paediatric vasculitis 168The epidemiology of paediatric vasculitis 171The investigation of primary systemic vasculitis 172The standard treatment of childhood vasculitis 174Henoch–Schönlein purpura 179Kawasaki disease 183The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides 188Polyarteritis nodosa (PAN) 192Cutaneous polyarteritis nodosa (cPAN) ...
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25

Systemic diseases. Elsevier Science Publishers, 1993.

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26

(Editor), Rolando Cimaz, Thomas Lehman (Editor), and Ronald Asherson (Series Editor), eds. Pediatrics in Systemic Autoimmune Diseases, Volume 6 (Handbook of Systemic Autoimmune Diseases) (Handbook of Systemic Autoimmune Diseases). Elsevier Science, 2007.

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27

Systemic Diseases, Part III. Elsevier, 1998.

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28

Human Diseases: Systemic Approach. Appleton & Lange, 2001.

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29

(Editor), Harold L. Klawans, ed. Systemic Diseases, Part I. Elsevier Science Ltd, 1993.

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30

Ohira, Hiromasa. Liver in Systemic Diseases. Springer London, Limited, 2016.

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31

(Editor), Christopher G. Goetz, and Michael J. Aminoff (Editor), eds. Systemic Diseases, Part II. Elsevier, 1998.

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32

Portincasa, Piero, Gema Frühbeck, and Hendrik M. Nathoe. Endocrinology and Systemic Diseases. Springer, 2021.

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33

Endocrinology and Systemic Diseases. Springer, 2021.

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34

(Editor), Justin Mason, Charles Pusey (Editor), and Ronald Asherson (Series Editor), eds. The Kidney in Systemic Autoimmune Diseases, Volume 7 (Handbook of Systemic Autoimmune Diseases) (Handbook of Systemic Autoimmune Diseases). Elsevier Science, 2007.

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35

Sclera & Systemic Disorders. 2nd ed. Butterworth-Heinemann, 2003.

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36

Dorea, Andrea, Paolo Pauletto, Ronald Asherson, and Andrea Doria. Heart in Systemic Autoimmune Diseases. Elsevier Science & Technology Books, 2004.

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37

Sataloff, Robert T., and Abdul-Latif Hamdan. Laryngeal Manifestations of Systemic Diseases. Plural Publishing, Incorporated, 2018.

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38

Hagendorff, Andreas. Cardiac involvement in systemic diseases. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199599639.003.0020.

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Systemic diseases are generally an interdisciplinary challenge in clinical practice. Systemic diseases are able to induce tissue damage in different organs with ongoing duration of the illness. The heart and the circulation are important targets in systemic diseases. The cardiac involvement in systemic diseases normally introduces a chronic process of alterations in cardiac tissue, which causes cardiac failure in the end stage of the diseases or causes dangerous and life-threatening problems by induced acute cardiac events, such as myocardial infarction due to coronary thrombosis. Thus, diagno
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39

Verleden,, G. M., M. G. Demedts, R. Westhovens, and M. Thomeer, eds. Pulmonary Manifestations of Systemic Diseases. European Respiratory Society, 2005. http://dx.doi.org/10.1183/1025448x.erm3405.

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40

Płońska-Gościniak, Edyta, Michal Ciurzynski, Marcin Fijalkowski, et al. Cardiac involvement in systemic diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0057.

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Cardiovascular features in systemic diseases are common. Transthoracic echocardiography represents a first-line diagnostic tool among these patients. Pericarditis is the most frequent cardiac complication of rheumatoid arthritis. In systemic lupus erythematosus, echocardiography shows usually small or moderate pericardial effusion in up to 55% of patients. In this group, Libman-Sacks vegetations develop mainly on the mitral valve but also can be seen on other valves. Pulmonary hypertension is one of the most important complications adversely influencing survival of systemic sclerosis patients.
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41

Yadav, Dr Anuradha, Dr Swati Dahiya, Dr Niraj Kumar, and Dr Kajal Malhotra, eds. Oral Manifestations of Systemic Diseases. AkiNik Publications, 2022. http://dx.doi.org/10.22271/ed.book.1798.

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42

Pediatrics in Systemic Autoimmune Diseases. Elsevier, 2016. http://dx.doi.org/10.1016/c2014-0-04556-x.

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43

Pediatrics in Systemic Autoimmune Diseases. Elsevier, 2007. http://dx.doi.org/10.1016/s1571-5078(07)x0600-7.

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44

Oral Inflammations and Systemic Diseases. MDPI, 2020. http://dx.doi.org/10.3390/books978-3-03936-289-9.

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45

Roy, Frederick. Ocular Syndromes and Systemic Diseases. Jaypee Brothers Medical Publishers (P) Ltd., 2014. http://dx.doi.org/10.5005/jp/books/12136.

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46

Roy, Frederick Hampton. Ocular Syndromes and Systemic Diseases. 3rd ed. Lippincott Williams & Wilkins, 2002.

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47

Nasal manifestations of systemic diseases. OceanSide Publications, 1991.

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48

Asherson, Ronald, Andrea Doria, Piercarlo Sarzi-Puttini, Annegret Kuhn, and Giampietro Girolomoni. Skin in Systemic Autoimmune Diseases. Elsevier Science & Technology Books, 2006.

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49

Ocular syndromes and systemic diseases. Grune & Stratton, 1985.

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50

Oral Manifestations of Systemic Diseases. 2nd ed. W.B. Saunders Company, 1990.

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