Academic literature on the topic 'Ulipristal acetate'

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Journal articles on the topic "Ulipristal acetate"

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DURAN, Mehmet Nuri, Hacı Öztürk ŞAHİN, Nihal KILINÇ, and Bülent DEMİR. "The Effect of Ulipristal Acetate on Surgical Endometriosis Created in Rats." Artuklu International Journal of Health Sciences 2, no. 3 (2022): 15–19. http://dx.doi.org/10.58252/artukluder.1180091.

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Objective: The effect of Ulipristal Acetate on endometriosis foci created in rats was investigated. Methods: The study was conducted with 12-week-old rats weighing approximately 280 grams. After creating an autologous endometriosis model, the group that did not receive ulipristal acetate negative was administered with oral saline daily, and the group given ulipristal acetate positive was administered with 0.5 mg/kg (0.125 mg/rat/day) orally for 4 weeks. Ectopic endometrial tissues were removed for histopathological and immunohistochemical evaluations. Staining was performed with Hematoxylin Eo
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Kavitha, Veladanda, and Rachamalla Madhuri. "Ulipristal Acetate Versus Leuprolide Acetate in Medical Management of Uterine Fibroids." Journal of Evolution of Medical and Dental Sciences 10, no. 43 (2021): 3701–6. http://dx.doi.org/10.14260/jemds/2021/749.

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BACKGROUND We wanted to compare the effectiveness of the treatment and the adverse effects of ulipristal acetate and leuprolide acetate in the medical management of symptomatic uterine fibroids. METHODS This is a randomised controlled study conducted in the the Department of Obstetrics and Gynaecology in Chalmeda Anand Rao Institute of Medical Sciences from January 2019 to January 2020. 60 patients with symptomatic fibroids and excessive uterine bleeding were randomly divided. They were given daily therapy of ulipristal acetate 10 mg orally for 3 months or monthly injection leuprolide acetate
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McKeage, Kate, and Jamie D. Croxtall. "Ulipristal Acetate." Drugs 71, no. 7 (2011): 935–45. http://dx.doi.org/10.2165/11207410-000000000-00000.

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Croxtall, Jamie D. "Ulipristal Acetate." Drugs 72, no. 8 (2012): 1075–85. http://dx.doi.org/10.2165/11209400-000000000-00000.

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Mozzanega, Bruno, Salvatore Gizzo, Stefania Di Gangi, Erich Cosmi, and Giovanni Battista Nardelli. "Ulipristal Acetate." Reproductive Sciences 21, no. 6 (2014): 678–85. http://dx.doi.org/10.1177/1933719113519178.

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Lei, Rong Rong, Zuo Liang Sha, Liang Zhu, Li Bin Yang, and Yan Fei Wang. "Investigation on Thermal Decomposition Kinetics of Ulipristal Acetate (Form B)." Advanced Materials Research 791-793 (September 2013): 260–64. http://dx.doi.org/10.4028/www.scientific.net/amr.791-793.260.

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Non-isothermal thermogravimetry analysis was applied to study the thermal decomposition kinetics of ulipristal acetate (form B). According to the experimental result, ulipristal acetate (form B) decomposed included three steps. Based on different kinetics function of corresponding thermal decomposition mechanisms and experimental data of ulipristal acetate (form B), decomposition mechanisms of three steps of ulipristal acetate (form B) were analyzed by differential method. According to fitting results of different mechanism functions, decomposition mechanisms of three steps of ulipristal aceta
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Shipika. "Ulipristal Acetate versus Placebo for Fibroid Treatment." International Journal of Toxicological and Pharmacological Research 13, no. 9 (2023): 206–11. https://doi.org/10.5281/zenodo.11081891.

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<strong>Background:&nbsp;</strong>The efficacy and safety of oral ulipristal acetate for the treatment of symptomatic uterine fibroids before surgery are uncertain.&nbsp;<strong>Methods:&nbsp;</strong>We randomly assigned women with symptomatic fibroids, excessive uterine bleeding (a score of &gt;100 on the pictorial blood-loss assessment chart [PBAC, an objective assessment of blood loss, in which monthly scores range from 0 to &gt;500, with higher numbers indicating more bleeding]) and anemia (hemoglobin level of &le;10.2 g per deciliter) to receive treatment for up to 13 weeks with oral uli
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a, Shipika. "ULIPRISTAL ACETATE VERSUS PLACEBO FOR FIBROID TREATMENT." International Journal of Advanced Research 11, no. 07 (2023): 1348–54. http://dx.doi.org/10.21474/ijar01/17351.

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Background: The efficacy and safety of oral ulipristal acetate for the treatment of symptomatic uterine fibroids before surgery are uncertain. Methods: We randomly assigned women with symptomatic fibroids, excessive uterine bleeding (a score of &gt;100 on the pictorial blood-loss assessment chart [PBAC, an objective assessment of blood loss, in which monthly scores range from 0 to &gt;500, with higher numbers indicating more bleeding]) and anemia (hemoglobin level of ≤10.2 g per deciliter) to receive treatment for up to 13 weeks with oral ulipristal acetate at a dose of 5 mg per day (96 wome
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a, Shipika. "ULIPRISTAL ACETATE VERSUS PLACEBO FOR FIBROID TREATMENT." International Journal of Advanced Research 11, no. 07 (2023): 1234–40. http://dx.doi.org/10.21474/ijar01/17342.

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Background: The efficacy and safety of oral ulipristal acetate for the treatment of symptomatic uterine fibroids before surgery are uncertain. Methods: We randomly assigned women with symptomatic fibroids, excessive uterine bleeding (a score of &gt;100 on the pictorial blood-loss assessment chart [PBAC, an objective assessment of blood loss, in which monthly scores range from 0 to &gt;500, with higher numbers indicating more bleeding]) and anemia (hemoglobin level of ≤10.2 g per deciliter) to receive treatment for up to 13 weeks with oral ulipristal acetate at a dose of 5 mg per day (96 wome
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Costa, Ana R., Ana P. Carvalho, Diana R. Martins, et al. "Series of 55 pregnancies following ulipristal acetate treatment of symptomatic uterine fibroids." Journal of Endometriosis and Pelvic Pain Disorders 12, no. 3-4 (2020): 170–75. http://dx.doi.org/10.1177/2284026520932468.

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Introduction: Treatment with ulipristal acetate effectively controls excessive bleeding due to uterine fibroids and reduces their size. Uterine fibroid size reduction is expected to improve the results of the myomectomy and the reproductive prospects of the patient. Methods: Retrospective and descriptive analysis of a series of 53 patients who achieved pregnancy after being treated for symptomatic uterine fibroids. The primary endpoints were pregnancy and birth outcomes in women with symptomatic uterine fibroids that conceived following at least one course of therapy with ulipristal acetate 5
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Dissertations / Theses on the topic "Ulipristal acetate"

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Li, Yingxing, and 李莹星. "Role of ulipristal acetate in regulating endometrial gene expression and spheroids attachment." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hdl.handle.net/10722/211559.

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The novel emergency contraceptive Ulipristal acetate (UPA) belongs to the progesterone receptor modulator family. A single oral dosage of 30mg UPA within 120 hours of unprotected intercourse could delay ovulation and differentiation of endometrium. Yet, whether UPA affect embryo implantation remains largely unknown. This study aims to investigate whether UPA affect endometrial gene expressions and embryo attachment onto endometrial epithelial cells. The PR-expressing human endometrial carcinoma cell line Ishikawa was used and treated with 10nM estrogen, 1μM progesterone or 4μM UPA for 24 ho
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Whitaker, Lucy Harriet Ravenscroft. "Effect of administration of selective progesterone receptor modulators (SPRMs) on uterine and endometrial morphology." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/28974.

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Introduction: The human menstrual cycle is regulated by sex-steroid hormones, including oestrogen (E), progesterone (P4) and androgens which act by ligand binding to their cognate receptors. Perturbation of the complex series of events governing the menstrual cycle may lead to heavy menstrual bleeding (HMB). This is a common debilitating condition and often associated with uterine fibroids. There remains an unmet need for effective, long-term medical treatment so women avoid surgery and preserve their fertility. Selective progesterone receptor modulators (SPRMs, e.g. ulipristal acetate, UPA) a
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Buechner-wiegand, Dana K. "Contraception Management at Point of Care for Emergency Contraception." Otterbein University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=otbn1367841736.

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Simpson, Paul. "A study of the histopathological changes within ectopic endometrial tissue, in subjects with known pelvic endometriosis, following treatment with ulipristal acetate, a Selective Progesterone Receptor Modulator (SPRM)." Thesis, University of East Anglia, 2018. https://ueaeprints.uea.ac.uk/67857/.

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Endometriosis is a common disease, affecting 10% of women of reproductive age. Pharmacological agents play an important role in control of symptoms as well as disease suppression but are limited by systemic side effects. Although surgical management is helpful for some, there is an increasing reliance on medical treatment and the exploration of new treatments such as selective progesterone receptor modulators (SPRMs). The aim of this interventional descriptive cohort study was to assess the changes in the ectopic endometrial deposits of twenty patients with pelvic endometriosis after a three-m
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Esber, Nathalie. "Effets des modulateurs du récepteur de la progestérone dans des modèles de cancer mammaire humain." Thesis, Université Paris-Saclay (ComUE), 2015. http://www.theses.fr/2015SACLS058/document.

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Le rôle des progestatifs et du récepteur de la progestérone (PR) dans la carcinogénèse mammaire est maintenant établi. Le PR est exprimé sous deux isoformes PRA et PRB dont l'expression est équimolaire mais qui différent par leur activité transcriptionnelle des gènes cibles. La surexpression de PRA est associée à un pronostic défavorable du cancer mammaire, et est observée chez les femmes à haut risque génétique de cancer du sein. L'utilisation d'antagonistes pour inhiber l'activité de PR pourrait constituer une stratégie thérapeutique potentielle. L'objectif de cette thèse a été d'évaluer les
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Bristot, Margarete. "Efetividade do acetato de ulipristal para miomatose uterina : revisão sistemática e metanálise." reponame:Repositório Institucional da UNESC, 2017. http://repositorio.unesc.net/handle/1/5191.

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Dissertação apresentada ao Programa de Pós-Graduação em Saúde Coletiva (Mestrado Profissional) da Universidade do Extremo Sul Catarinense - UNESC, como requisito para a obtenção do título de Mestre em Saúde Coletiva.<br>Os miomas uterinos são os tumores mais comuns do trato genital feminino, afetando as mulheres na sua idade produtiva e reprodutiva. Como seu manejo curativo ainda é eminentemente cirúrgico, o tratamento dos mesmos produz alto impacto econômico, onerando os serviços públicos de saúde. Diante disto, a busca por uma resolução medicamentosa se faz necessária. A comprovação da ação
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Baptista, Marta Adriana Natário. "Fibromiomas e preservação da fertilidade." Master's thesis, 2019. http://hdl.handle.net/10316/89853.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução: os fibromiomas ou fibroleiomiomas uterinos são os tumores benignos mais frequentes durante a idade reprodutiva. Podem causar grande desconforto no dia-a-dia da mulher e limitar o potencial da fertilidade feminina. Quando o tratamento é necessário, devem ser ponderados fatores como a idade, raça, desejo de gravidez futura e a classificação FIGO do fibromioma.Materiais e métodos: realizou-se a pesquisa através do Serviço da Biblioteca do Centro Hospitalar e Universitário de Coimbra e em plataforma
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Argiel, Agostina Daniela. "Mecanismos que regulan la fecundación en mamíferos: Modulación de la quimiotaxis espermática en bovinos mediada por acetato de ulipristal y zinc." Bachelor's thesis, 2018. http://hdl.handle.net/11086/6635.

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Tesina (Grado en Ciencias Biológicas)--Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Lugar de Trabajo: Centro de Biología Celular y Molecular-CEBICEM-2018. 36 h.; ils.; tabls. grafs. Contiene Referencia Bibliográfica.<br>Para que ocurra la fecundación en mamíferos se tiene que producir el encuentro y fusión de las gametas femenina y masculina. Distintos mecanismos, como la quimiotaxis, guían a los espermatozoides en su viaje por el tracto reproductor femenino, para facilitar el encuentro del ovocito. Las células del cumulus que rodean al ovocito secretan
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Gomes, Ana Cláudia Chapeira. "Pílula do dia seguinte: avaliação do conhecimento de utilização pela população." Master's thesis, 2014. http://hdl.handle.net/10400.6/5336.

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Este documento encontra-se dividido em três capítulos. No primeiro encontra-se desenvolvido o projeto de investigação, explorando um tema da área das Ciências Farmacêuticas e no segundo e terceiro são abordadas as experiências profissionalizantes nas vertentes de Farmácia Comunitária e Hospitalar. Durante os últimos anos, o acesso à pilula do dia seguinte tem sofrido alterações, tendo ocorrido um aumento do número deste tipo de pilulas vendidas em Portugal. A informação científica respeitante a esta temática é ainda limitada. Neste sentido, a componente de investigação desenvolvida centra-se
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Book chapters on the topic "Ulipristal acetate"

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"Ulipristal acetate." In Meyler's Side Effects of Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-444-53717-1.00048-2.

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"Ulipristal Acetate." In Hale’s Medications & Mothers’ Milk™ 2019. Springer Publishing Company, 2018. http://dx.doi.org/10.1891/9780826150356.1049.

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"Emergency Contraception—Ulipristal Acetate." In Canadian Family Practice Guidelines. Springer Publishing Company, 2019. http://dx.doi.org/10.1891/9780826194985.0075.

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"Emergency Contraception—Ulipristal Acetate, Family." In Family Practice Guidelines. Springer Publishing Company, 2020. http://dx.doi.org/10.1891/9780826153425.0025bh.

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Béni, Zoltán. "Structure Elucidation of a Mysterious Trace Component of Ulipristal Acetate." In Anthropic Awareness. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-419963-7.00010-9.

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Conference papers on the topic "Ulipristal acetate"

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Wagner, J. K., M. Hoeltzenbein, C. Schaefer, and K. Dathe. "Ulipristal acetate and pregnancy outcome – an observational study." In Kongressabstracts zur Tagung 2020 der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG). © 2020. Thieme. All rights reserved., 2020. http://dx.doi.org/10.1055/s-0040-1718100.

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Dooper, Marten. "Low-dose ulipristal acetate is an effective treatment for PMDD." In 35th ECNP Congress, edited by Christina Dalla. Medicom Medical Publishers, 2022. http://dx.doi.org/10.55788/5c1b0c62.

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Stanoulov, G., Bourazan A. Chalil, and P. Tsikouras. "Menstruation behavior after use of emergency contraception: Ulipristal acetate versus levonorgestrel in women of reproductive age." In Kongressabstracts zur Tagung 2020 der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG). © 2020. Thieme. All rights reserved., 2020. http://dx.doi.org/10.1055/s-0040-1717696.

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Dovnik, A., and M. Pakiž. "EP509 Case series of uterine sarcomas associated with preoperative treatment with ulipristal acetate for supposed symptomatic myomas." In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.567.

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Lee, Ha-Young, A. Ra Ko, Dong-Woo Kang, et al. "Abstract 1191: Anti-tumor effect of selective progesterone receptor modulator (ulipristal acetate) on endometrial cancer cell lines." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1191.

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Lee, Oukseub, Minhua Wang, Maarten C. Bosland, Omid Hosseini, Irene Helenowski, and Seema A. Khan. "Abstract PD11-08: Low dose endoxifen represses mouse mammary tumorigenesis: A preclinical study of monotherapy and combination with ulipristal acetate." In Abstracts: 2020 San Antonio Breast Cancer Virtual Symposium; December 8-11, 2020; San Antonio, Texas. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.sabcs20-pd11-08.

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Hwang, Jae Ryoung, Young-Jae Cho, Ji-Yoon Ryu, Ju-Yeon Choi, Jung-Joo Choi, and Jeong-Won Lee. "Ulipristal acetate, a selective progesterone receptor modulator, induces cell death via inhibition of STAT3/CCL2 signaling pathway in uterine sarcoma." In KSGO 2023. Korean Society of Gynecologic Oncology, 2023. http://dx.doi.org/10.3802/jgo.2023.34.s1.fp_u04.

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