Academic literature on the topic 'Urinary clusterine'

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Journal articles on the topic "Urinary clusterine"

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Sambara, Yuliana, Mansyur Arif, and Uleng Bahrun. "Pathomechanism of Renal Damage in Type 2 Diabetes Mellitus Patients." Indonesian Biomedical Journal 5, no. 3 (2013): 161. http://dx.doi.org/10.18585/inabj.v5i3.66.

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BACKGROUND: Hyperglycemia in diabetic patients cause both chronic inflammation and extracellular matrix accumulation that can lead to progressive renal damage. Albumin, Gammaglutamytransferase (GGT) and clusterin in urine are markers to detect damage in glomerulus, cell of the tubules and proximal tubules, respectively.METHODS: This study aimed to evaluate the pathomechanism of haemoglobin A1c (HbA1c), albumin, GGT, clusterin, type IV collagen in urine, and high sensitivity C-reactive protein (hsCRP) in type 2 diabetes mellitus (DM) patients. The study was a cross sectional study involving 82
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Musiał, Kinga, Monika Augustynowicz, Izabella Miśkiewicz-Migoń, Krzysztof Kałwak, Marek Ussowicz, and Danuta Zwolińska. "Clusterin as a New Marker of Kidney Injury in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Pilot Study." Journal of Clinical Medicine 9, no. 8 (2020): 2599. http://dx.doi.org/10.3390/jcm9082599.

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Background and aims: The markers of renal damage defining subclinical AKI are not widely used in children undergoing allogeneic hematopoietic stem cell transplantation (alloHSCT). The aim of the study was to evaluate serum and urinary clusterin as indices of kidney injury after alloHSCT in relation to damage (kidney injury molecule (KIM)-1) and functional (cystatin C) markers. Material and methods: Serum and urinary clusterin, KIM-1 and cystatin C concentrations were assessed by ELISA in 27 children before alloHSCT, 24 h, 1, 2, 3 and 4 weeks after alloHSCT and in controls. Results: All paramet
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Dodiya, Hardik, Mukul Jain, and Sunita S. Goswami. "Renal Toxicity of Lisinopril and Rosuvastatin, Alone and in Combination, in Wistar Rats." International Journal of Toxicology 30, no. 5 (2011): 518–27. http://dx.doi.org/10.1177/1091581811415293.

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The aim of study was to evaluate the effect of commonly used lisinopril, rosuvastatin and their combined action on site-specific nephrotoxicity in rats using clusterin and microalbumin nephrotoxic biomarkers and other related parameters using oral gavage. Rosuvastatin at 2 different doses showed increase in urinary microalbumin levels whereas lisinopril and its combination with rosuvastatin at 2 different doses did not show urinary microalbumin excretion indicating beneficial effects of lisinopril in terms of reducing microalbumin. Urinary clusterin levels significantly increased in high-dose
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Martynova, Ekaterina V., Adelya N. Maksudova, Venera G. Shakirova, et al. "Urinary Clusterin Is Upregulated in Nephropathia Epidemica." Disease Markers 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/8658507.

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Kidney insufficiency is a hallmark of nephropathia epidemica (NE). Little is known about the mechanisms of the NE kidney pathology, with current knowledge mainly based on findings in postmortem tissue. We have analyzed kidney damage biomarkers in urine collected from early- and late-phase NE using Bio-Plex kidney toxicity panels 1 and 2. To determine the disease specificity, kidney damage biomarkers were also analyzed in urine samples from patients diagnosed with gout, type 2 diabetes, systemic lupus erythematosus, and chronic kidney insufficiency. Analysis of 12 biomarkers suggests damage to
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Esteban-Fernández, Adelaida, Clara Ibañez, Carolina Simó, Begoña Bartolomé, and Victoria Moreno Arribas. "Metabolome-based clustering after moderate wine consumption." OENO One 54, no. 3 (2020): 455–67. http://dx.doi.org/10.20870/oeno-one.2020.54..2983.

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Grouping individuals according to their metabolic capacities (metabotyping) has caused a shift from individualised to grouped treatments for the optimisation of nutritional interventions. Several studies have reported a stratification of patients into metabolic clusters after the intake of certain foods, of which polyphenols seem to be mostly associated with metabotypes. Despite this, there is a lack of metabotyping studies regarding wine consumption. In this context, the human urinary metabolome of healthy volunteers (n=41) was explored by means of a non-targeted metabolomic approach after an
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Jiang, Yuan-Hong, Jia-Fong Jhang, Jen-Hung Wang, Ya-Hui Wu, and Hann-Chorng Kuo. "Applying K-Means Cluster Analysis to Urinary Biomarkers in Interstitial Cystitis/Bladder Pain Syndrome: A New Perspective on Disease Classification." International Journal of Molecular Sciences 26, no. 8 (2025): 3712. https://doi.org/10.3390/ijms26083712.

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This study applied K-means cluster analysis to urinary biomarker profiles in interstitial cystitis/bladder pain syndrome (IC/BPS) patients, aiming to provide a new perspective on disease classification and its clinical relevance. We retrospectively analyzed urine samples from 127 IC/BPS patients and 30 controls. The urinary levels of 10 inflammatory cytokines and three oxidative stress markers (8-hydroxy-2-deoxyguanosin [8-OHdG], 8-isoprostane, and total antioxidant capacity [TAC]) were quantified. K-means clustering was performed to identify biomarker-based patient subgroups. IC/BPS patients
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Eti, S., C. Y. Cheng, A. Marshall, and M. M. Reidenberg. "Urinary Clusterin in Chronic Nephrotoxicity in the Rat." Experimental Biology and Medicine 202, no. 4 (1993): 487–90. http://dx.doi.org/10.3181/00379727-202-43564.

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García-Martínez, Juan D., Asta Tvarijonaviciute, José J. Cerón, Marco Caldin, and Silvia Martínez-Subiela. "Urinary clusterin as a renal marker in dogs." Journal of Veterinary Diagnostic Investigation 24, no. 2 (2012): 301–6. http://dx.doi.org/10.1177/1040638711435112.

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Mavrogeorgis, Emmanouil, Sophie Valkenburg, Justyna Siwy, et al. "Integration of Urinary Peptidome and Fecal Microbiome to Explore Patient Clustering in Chronic Kidney Disease." Proteomes 12, no. 2 (2024): 11. http://dx.doi.org/10.3390/proteomes12020011.

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Millions of people worldwide currently suffer from chronic kidney disease (CKD), requiring kidney replacement therapy at the end stage. Endeavors to better understand CKD pathophysiology from an omics perspective have revealed major molecular players in several sample sources. Focusing on non-invasive sources, gut microbial communities appear to be disturbed in CKD, while numerous human urinary peptides are also dysregulated. Nevertheless, studies often focus on isolated omics techniques, thus potentially missing the complementary pathophysiological information that multidisciplinary approache
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Purohit, Rajveer S., and Marshall L. Stoller. "Stone clustering of patients with cystine urinary stone formation." Urology 63, no. 4 (2004): 630–34. http://dx.doi.org/10.1016/j.urology.2003.11.045.

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Dissertations / Theses on the topic "Urinary clusterine"

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Mendonça, Joana da Silva. "Estudo comparativo de biomarcadores renais (Dimetilarginina Simétrica e Clusterina urinária) em gatos seniores e geriátricos sem azotemia." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2018. http://hdl.handle.net/10400.5/15002.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>A doença renal crónica é uma das doenças mais frequentemente diagnosticada em gatos seniores e geriátricos, caracterizando-se pela perda de nefrónios funcionais. Dadas as características desta doença e a elevada prevalência em gatos, tem sido dada cada vez mais importância ao estudo de marcadores renais que permitam o diagnóstico precoce da doença e que sejam capazes de detetar lesões renais agudas, visto que o biomarcador padrão de função renal (creatinina) não tem sensibilidade para detetar precocemente a doença. A importância do
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Afonso, Joana Cabrita. "A clusterina urinária como biomarcador para o diagnóstico precoce de doença renal crónica em felídeos." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2021. http://hdl.handle.net/10400.5/21245.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>A doença renal crónica carateriza-se por uma diminuição permanente do número de nefrónios funcionais e é a doença renal mais frequentemente diagnosticada no gato, estimando-se que em felídeos com mais de 10 anos a prevalência esteja entre 30 e 40%. Apesar de recentemente ter sido validado um biomarcador com maior sensibilidade do que a creatinina para deteção precoce de perda de função renal, a dimetilarginina simétrica, o diagnóstico da doença continua a fazer-se relativamente tarde, o que traz consequências a nível do prognóstico e
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Books on the topic "Urinary clusterine"

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Radović, Milan, and Adalbert Schiller. Balkan endemic nephropathy. Edited by Adrian Covic. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0090_update_001.

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Balkan endemic nephropathy (BEN) is a chronic, slowly progressive tubulointerstitial nephritis, with familial clustering, occurring in several endemic rural regions in countries of the Balkan Peninsula. BEN is characterized by anaemia, tubular proteinuria, renal shrinkage, and slowly declining glomerular filtration rate (GFR). Up to one-third of patients may also develop upper urothelial tumours. The aetiology of BEN is unclear; chronic exposure to aristolochic acid and a polygenic predisposition are the most likely contributing factors. The major pathological characteristics of BEN are symmet
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Book chapters on the topic "Urinary clusterine"

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Laurikkala, Jorma, and Martti Juhola. "Hierarchical Clustering of Female Urinary Incontinence Data Having Noise and Outliers." In Medical Data Analysis. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/3-540-45497-7_24.

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Mao, Lingchao, Kimia Vahdat, Sara Shashaani, and Julie L. Swann. "Personalized Predictions for Unplanned Urinary Tract Infection Hospitalizations with Hierarchical Clustering." In Springer Proceedings in Business and Economics. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-75166-1_34.

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Laurikkala Jorma and Juhola Martti. "Hierarchical Clustering of Fuzzy Data on Female Urinary Incontinence." In Studies in Health Technology and Informatics. IOS Press, 2001. https://doi.org/10.3233/978-1-60750-928-8-578.

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