Bibliografías temáticas / Cellular immunity and chemotherapy, immune status of cancer patients

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Literatura académica sobre el tema "Cellular immunity and chemotherapy, immune status of cancer patients"

Autor: Grafiati

Publicado: 4 de junio de 2021

Última modificación: 10 de febrero de 2022

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Artículos de revistas sobre el tema "Cellular immunity and chemotherapy, immune status of cancer patients"

Schantz, S. P., H. E. Savage, T. Racz, et al. "Immunologic determinants of head and neck cancer response to induction chemotherapy." Journal of Clinical Oncology 7, no. 7 (1989): 857–64. http://dx.doi.org/10.1200/jco.1989.7.7.857.

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Various measures of immune response were assessed prior to induction chemotherapy (intravenous [IV] cisplatin, fluorouracil [5-FU], and bleomycin) in 43 previously untreated head and neck cancer patients to derive a clinical response prediction model. These were parameters of functional cellular immunity (natural killer [NK] cell activity, lymphocyte blastogenesis response to mitogens), total lymphocyte and lymphocyte subset numbers and percentages, and circulating humoral immunity (total immunoglobulin, immunoglobulin classes, and C1q binding activity [C1q BA]). The C1q BA may reflect levels

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Khakimova, G. G., A. A. Tryakin, T. N. Zabotina, and Sh G. Khakimova. "Comprehensive assessment of the systemic and local immunity, inflammatory factors and clinical indicators in patients with gastric cancer." Malignant tumours 10, no. 4 (2021): 5–15. http://dx.doi.org/10.18027/2224-5057-2020-10-4-5-15.

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Objective.To study the state of cellular immunity and local immunity in patients with gastric adenocarcinoma.Materials and methods.From 2017 to 2018 45 primary patients with gastric adenocarcinoma (25 — with stages I–III, 20 — with stage IV) received surgical / combined treatment or chemotherapy at the Blokhin Scientific Research Center of Oncology, respectively. Peripheral blood and tumor tissue were collected before starting treatment. The percentage of the degree of infiltration of tumor tissue by lymphocytes (CD45 + CD14‑TILs) was assessed by flow cytometry: T‑cells (CD3 + CD19‑TILs), B‑ce

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Mantovani, Stefania, Barbara Oliviero, Stefania Varchetta, Dalila Mele, and Mario U. Mondelli. "Natural Killer Cell Responses in Hepatocellular Carcinoma: Implications for Novel Immunotherapeutic Approaches." Cancers 12, no. 4 (2020): 926. http://dx.doi.org/10.3390/cancers12040926.

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Hepatocellular carcinoma (HCC) still represents a significant complication of chronic liver disease, particularly when cirrhosis ensues. Current treatment options include surgery, loco-regional procedures and chemotherapy, according to specific clinical practice guidelines. Immunotherapy with check-point inhibitors, aimed at rescuing T-cells from exhaustion, has been applied as second-line therapy with limited and variable success. Natural killer (NK) cells are an essential component of innate immunity against cancer and changes in phenotype and function have been described in patients with HC

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Diplas, Bill, Ryan Ptashkin, Andrea Cercek, et al. "Clinical relevance of clonal hematopoiesis in metastatic gastrointestinal malignancies." Journal of Clinical Oncology 39, no. 15_suppl (2021): e16082-e16082. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e16082.

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e16082 Background: Clonal hematopoiesis (CH) represents non-random clonal selection of bone marrow-derived cells marked by somatic mutations in certain genes. The presence of CH is associated with development of atherosclerosis and leukemia, and accelerated by toxic exposures (chemotherapy, radiation, smoking) and aging (Jaiswal et al. NEJM 2017; Abelson et al. Nature 2018). The impact of these genetic alterations on cellular function is unknown, especially in the broader context of immunity and in response to cancer therapy. To determine the contribution of CH to therapeutic response and hema

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DeJoubner, Nutan Jyothi, Hyunseok Kang, Qunna Li, et al. "Prognostic impact of circulating endothelial cell counts in patients with advanced non-small cell lung cancer." Journal of Clinical Oncology 30, no. 15_suppl (2012): e21045-e21045. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e21045.

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e21045 Background: Blood progenitor cells expressing the stem cell marker CD34 have been associated with prognosis in cancer. We hypothesized that non-small cell lung cancer (NSCLC) patients with higher numbers of circulating CD34+ endothelial progenitor cells (CD34+/CD146+/CD45-, CEC) would have worse post-treatment outcomes and patients with more hematopoietic progenitor cells (CD34+/CD45+/CD45dim/CD133+, HPC) would have better outcomes. Methods: Blood samples from patients with advanced NSCLC were analyzed at 3 time points: prior to chemotherapy, after cycle one, and at completion of treatm

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Zemskov, Vladimir M., Konstantin N. Pronko, Dmitrii A. Ionkin, et al. "Immune Status of Pancreatic Cancer Patients Receiving Cryosurgery." Medical Sciences 7, no. 6 (2019): 73. http://dx.doi.org/10.3390/medsci7060073.

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Cryosurgery used on patients with unresectable pancreatic cancer improved their quality of life, but mainly because of the pain relief. In postoperative patients, multifaceted changes in immunity were found, and the state of the immune system prior to surgery often was a decisive factor to indicate whether further disorders in the postoperative period would develop, or by contrast, it would boost its recovery. Some patients receiving cryosurgery showed immune system imbalance and activation, and of antitumor immunity in particular. It has been suggested that the advisability of immunotropic th

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Pais, Irene, Nuno Correia, Isabel Pimentel, et al. "Effects of Acupuncture on Leucopenia, Neutropenia, NK, and B Cells in Cancer Patients: A Randomized Pilot Study." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/217397.

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Chemotherapy is one of most significant therapeutic approaches to cancer. Immune system functional state is considered a major prognostic and predictive impact on the success of chemotherapy and it has an important role on patients’ psychoemotional state and quality of life. In Chinese medicine, chemotherapy is understood as “toxic cold” that may induce a progressive hypofunctional state of immune system, thus compromising the fast recovery of immunity during chemotherapy. In this study, we performed a standardized acupuncture and moxibustion protocol to enhance immunity in cancer patients und

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Zavadova, Eva, Jan Spacek, Michal Vocka, Bohuslav Konopasek, and Lubos Petruzelka. "Decreased cellular and humoral immunity in patients with breast cancer." Journal of Clinical Oncology 36, no. 5_suppl (2018): 4. http://dx.doi.org/10.1200/jco.2018.36.5_suppl.4.

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4 Background: A growing body of evidence over the past few years suggests that the presence of immune elements within the tumor or in the tumor stroma has prognostic and predictive value in breast cancer. Immunotherapy is successfully used in many types of cancer, and modulation of immune system became standard part of the cancer patients treatment Responses in breast cancer have been more recently reported. However it has yet to be determined whether predictable biomarkers of response can be identified. Therefore in recent years, research focused on a precise description of the status and fun

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Jaunalksne, Inta, Simona Doniņa, Svetlana Čapenko, Maksims Čstjakovs, and Modra Murovska. "Cellular Immunity in Human Herpes Viruses 6 and 7 Infected Gastrointestinal Cancer Patients." Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 63, no. 4-5 (2009): 163–67. http://dx.doi.org/10.2478/v10046-009-0052-3.

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Cellular Immunity in Human Herpes Viruses 6 and 7 Infected Gastrointestinal Cancer Patients CD4+ T lymphocytes appear to be the preferential target for replication of HHV-6 (human herpes virus) as well as HHV-7 viruses in vivo. In addition, CD8+ T cells, monocytes/macrophages, natural killer cells, epithelial, endothelial, neural cells and fibroblasts may be infected. By definition, however, even a tumour designated by pathologists to be early stage may be late stage when considered by the immune system. Certainly, even early stage tumours have evaded immune control, suggesting that they have

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Kamaeva, Inna A., Irina B. Lysenko, Aleksandr B. Sagakyants, et al. "Parameters of cellular immunity in patients with lymphomas after COVID-19." Journal of Clinical Oncology 39, no. 15_suppl (2021): e19572-e19572. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e19572.

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e19572 Background: The development of lymphomas is accompanied by disorders in the structural and functional organization of the immune system leading to immune deficiency. Such patients are at greater risk of severe SARS-CoV infection. Our purpose was to assess the parameters of cellular immunity in patients with lymphomas with a history of multi-course chemotherapy, therapy with anti-CD20+ antibodies and PCR-confirmed COVID19. Methods: The study included 12 adult patients with lymphoproliferative diseases (non-Hodgkin's large B-cell lymphomas (NHL) - 7, Hodgkin's lymphomas (HL) - 5) with a h

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Tesis sobre el tema "Cellular immunity and chemotherapy, immune status of cancer patients"

Grunemann, Karoline. "Chemotherapeutische Beeinflussung des zellulären Immunstatus bei Patienten mit erstmanifestierten soliden Tumoren des Gastrointestinaltraktes." Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-71548.

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In der vorliegenden Arbeit wurde der zelluläre Immunstatus von 17 Patienten mit Erstdiagnose eines soliden gastrointestinalen Tumors vor und nach intravenöser Applikation von drei Zyklen einer konventionellen Polychemotherapie untersucht. Verglichen wurde zu Beginn der Therapie mit einer Kontrollgruppe, bestehend aus 21 nicht onkologisch vorerkrankten Probanden. Zur Messung der individuellen T-Zellvermittelten Immunantwort auf Einzelzellebene wird auf die Methode des IFN-γ-ELISPOT-Assays zurückgegriffen. Die zentrale Frage war, ob die Applikation einer Polychemotherapie einen messbaren Effek

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Grunemann, Karoline. "Chemotherapeutische Beeinflussung des zellulären Immunstatus bei Patienten mit erstmanifestierten soliden Tumoren des Gastrointestinaltraktes: Chemotherapeutische Beeinflussung des zellulärenImmunstatus bei Patienten mit erstmanifestierten solidenTumoren des Gastrointestinaltraktes." Doctoral thesis, 2010. https://ul.qucosa.de/id/qucosa%3A11239.

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