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Articles de revues sur le sujet « Cellules MIAMI »

Auteur : Grafiati

Publié le 4 juin 2021

Mis à jour le 1 février 2022

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1

Li, Ye, Wenjing Wang, Xiaoxue Xu, Shiyue Sun, Xiaoyu Xu, and Xian-jun Qu. "{2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic Acid Methyl Ester Inhibited Hepatocellular Carcinoma Growth in Bel-7402 Cells and Its Resistant Variants by Activation of NOX4 and SIRT3." BioMed Research International 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/491205.

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{2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic acid methyl ester (MIAM) is a novel indole compound, which possessed high efficacy against many cancers xenografted in mice without obvious toxicity. In this study, we aimed to investigate the effects of MIAM on human hepatocellular carcinoma (HCC) Bel-7402 cells and its resistant variants Bel-7402/5FU. MIAM inhibited the growth of HCC more potent in Bel-7402/5FU cells than its parent cells. MIAM increased cellular reactive oxygen species (ROS) levels, induced cell apoptosis, and arrested cell cycle in G0/G1pha

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Mitsui, A., S. Cao, A. Takahashi, and T. Arai. "Growth synchrony and cellular parameters of the unicellular nitrogen-fixing marine cyanobacterium, Synechococcus sp. strain Miami BG 043511 under continuous illumination." Physiologia Plantarum 69, no. 1 (1987): 1–8. http://dx.doi.org/10.1111/j.1399-3054.1987.tb01938.x.

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Suter, Robert, Vasileios Stathias, Anna Jermakowicz, et al. "COMP-16. COMPREHENSIVE TRANSCRIPTOMIC ANALYSIS OF SINGLE CELLS FROM RECURRENT AND PRIMARY GLIOBLASTOMA TO PREDICT CELL-TYPE SPECIFIC THERAPEUTICS." Neuro-Oncology 21, Supplement_6 (2019): vi64. http://dx.doi.org/10.1093/neuonc/noz175.259.

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Abstract Glioblastoma (GBM) remains the most common adult brain tumor, with poor survival expectations, and no new therapeutic modalities approved in the last decade. Our laboratories have recently demonstrated that the integration of a transcriptional disease signature obtained from The Cancer Genome Atlas’ GBM dataset with transcriptional cell drug-response signatures in the LINCS L1000 dataset yields possible combinatorial therapeutics. Considering the extreme intra-tumor heterogeneity associated with the disease, we hypothesize that the utilization of single-cell RNA-sequencing (scRNA-seq)

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Farhangi, Monika, Ryan J. Diel, Dawn C. Buse, et al. "Individuals with migraine have a different dry eye symptom profile than individuals without migraine." British Journal of Ophthalmology 104, no. 2 (2019): 260–64. http://dx.doi.org/10.1136/bjophthalmol-2018-313471.

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BackgroundMany individuals with migraine report symptoms of dry eye (DE). However, it is not known whether DE profiles are similar between individuals with and without migraine. To bridge this gap, we evaluated symptoms and signs of DE, including symptoms suggestive of nerve dysfunction, in a large group of individuals with DE symptoms, and compared profiles between individuals with migraine and those without migraine or headache.MethodsProspective cross-sectional study of individuals with DE symptoms seen at the Miami VA.ResultsOf 250 individuals, 31 met International Classification of Headac

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Gozes, Illana, and Douglas E. Brenneman. "Summer Neuropeptide Conference: The 14th Annual Meeting of the Summer Neuropeptide Conference, Miami Beach, Florida, USA, July 5–9, 2004." Neuropeptides 39, no. 1 (2005): 29–33. http://dx.doi.org/10.1016/j.npep.2004.09.001.

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Diel, Ryan J., Jodi Hwang, Zachary A. Kroeger, et al. "Photophobia and sensations of dryness in patients with migraine occur independent of baseline tear volume and improve following botulinum toxin A injections." British Journal of Ophthalmology 103, no. 8 (2018): 1024–29. http://dx.doi.org/10.1136/bjophthalmol-2018-312649.

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BackgroundTo evaluate the efficacy of botulinum toxin A (BoNT-A) in reducing photophobia and dry eye symptoms in individuals with chronic migraine. Additionally, we aimed to evaluate tear film volume as a potential contributor to symptoms in these patients.MethodsRetrospective review of 76 patients who received BoNT-A for chronic migraine between 23 August 2017 and 13 December 2017 at the Miami Veterans Affairs Medical Center Neurotoxin Clinic. Demographic data and all comorbidities were queried via chart review. Standardised validated surveys were administered to assess symptoms prior to and

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Bradley, Walter G. "Late effects of poliomyelitis.By L. S. Halstead, D. O. Wiechers, 236 pp, Symposia Foundation, Miami, FL, 1985. ($17.95 soft cover; $27.95 hard cover)." Muscle & Nerve 9, no. 5 (1986): 476. http://dx.doi.org/10.1002/mus.880090514.

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Ahmad, Sarfraz, Ali Amirkhosravi, Jamie M. Walker, et al. "Functional Consequences of Cellular Interactions with Heparin-PF4 Antibodies in Heparin-Induced Thrombocytopenia." Blood 104, no. 11 (2004): 3498. http://dx.doi.org/10.1182/blood.v104.11.3498.3498.

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Abstract Heparin-induced thrombocytopenia (HIT) is a potentially devastating complication of heparin therapy. The condition is due to formation of antibodies to the heparin-platelet factor 4 (HPF4) complex that activate platelets and/or endothelial cells by binding to FcγIIa (CD32) receptors. It is not clear why only a sub-population of patients that form HPF4 antibodies also develops clinical HIT, and why only a fraction of those develop thrombosis. We hypothesized that some functionally active HPF4 antibodies (i.e. that activate platelets) may also activate leukocytes and endothelial cells b

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Sandoval-Sus, Jose D., Damien Mikael Hansra, Maureen Cioffi Lavina, et al. "Pulmonary blastoma: A clinicopathologic study of three cases." Journal of Clinical Oncology 31, no. 15_suppl (2013): e19140-e19140. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e19140.

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e19140 Background: Pulmonary blastoma (PB) is a rare biphasic neoplasm representing 0.2-0.5% of pulmonary malignancies. Presentation ranges from asymptomatic to symptoms of advanced pulmonary tumors. Surgery is the preferred treatment with no consensus on the role of other adjuvant therapies. Methods: We report the clinicopathologic features of PB in 3 patients (pts). Retrospective review of medical records of pts diagnosed with PB at Jackson Memorial Hospital, Miami, FL since 2009. Staging performed using the 2009 AJCC system for NSCLC. Cases required pathological diagnosis before inclusion.

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Menapace, Bryan, Walter Jeske, Vicki Escalante, Erin Coglianese, Jeffrey Schwartz, and Jeanine M. Walenga. "Cellular Microparticles As Predictive Markers for Thrombosis and Other Clinical Events in Patients with Implanted Lvads." Blood 124, no. 21 (2014): 4995. http://dx.doi.org/10.1182/blood.v124.21.4995.4995.

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Abstract Introduction: Since the implantation of left ventricular assist devices (LVAD) in heart failure patients has become more frequent, the need to prevent, predict, and treat the associated pathologies has become paramount. The most common complications, which include thrombosis, gastrointestinal bleeds, anemia, and hemolysis, are also the adverse events that carry a less than favorable prognosis. Current methods for predicting these conditions, i.e. elevated LDH or low hemoglobin levels, typically provide an alert, at most, days in advance. This can result in inadequate time to prevent t

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Basher, Fahmin, Yonette Paul, and James E. Hoffman. "Clinical Outcomes in Relapsed/Refractory Multiple Myeloma Patients Receiving Sequential Elotuzumab and Daratumumab: A Single Center Experience." Blood 136, Supplement 1 (2020): 24. http://dx.doi.org/10.1182/blood-2020-142923.

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Daratumumab and elotuzumab are monoclonal antibodies approved by the FDA in November 2015 for the treatment of relapsed/refractory multiple myeloma (RRMM). Daratumumab was approved as a single therapy targeting plasma cell surface CD38, while elotuzumab was approved as part of combination therapy (with lenalidomide), targeting SLAMF7 to impact natural killer cell activation. While both therapies are involved in the recruitment of cellular cytotoxic mechanisms against multiple myeloma, the efficacy of each after a patient has relapsed on the other therapy is unclear. We conducted a retrospectiv

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Barletta, Pamela, Mukunthan Murthi, Douglas Salguero, and Mehdi Mirsaeidi. "Sarcoidosis as a paraneoplastic syndrome for breast cancer." Journal of Clinical Oncology 37, no. 15_suppl (2019): e12587-e12587. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e12587.

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e12587 Background: Sarcoidosis is a multisystem granulomatous disease of unknown etiology. The pathogenesis of sarcoidosis is believed to be a result from a cellular immune reaction from exposure to occupational, environmental, or infectious elements that lead to the formation of noncaseating granulomas. Non-caseating granulomas are also present in cancer , and it is well known that the cancer cells carry neo-antigens, leading to a possible association between cancer and sarcoidosis. Several studies have shown an increased risk of breast cancer , in particular, in patients with sarcoidosis, bu

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Iacono, E., B. Merlo, A. Spadari, G. Mari, F. Ricci, and P. Tazzari. "308 ISOLATION, DIFFERENTIATION, AND IMMUNOPHENOTYPIC CHARACTERIZATION OF MESENCHYMAL STEM CELLS DERIVED FROM EQUINE ADIPOSE TISSUE AND BONE MARROW." Reproduction, Fertility and Development 23, no. 1 (2011): 250. http://dx.doi.org/10.1071/rdv23n1ab308.

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Minimum criteria for the characterisation of human mesenchymal stem cells (MSC) are a) adhesion to the plastic when maintained under culture conditions; b) expression of CD105, CD73, and CD90, and no expression for CD45, CD34, and CD14; and c) differentiation into osteoblasts, adipocytes, and chondroblasts in vitro. One major difficulty in characterising equine MSC is the absence of specific monoclonal antibodies and evidence that certain markers from other species do not cross-react with the equine species. The aim of this work was to isolate, cultivate, differentiate, and conduct cellular ch

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Torres, Tania, Jeanine M. Walenga, Bryan Menapace, et al. "Are Microparticle Levels Useful for Detecting Thrombosis in Patients with Ventricular Assist Devices?" Blood 126, no. 23 (2015): 1115. http://dx.doi.org/10.1182/blood.v126.23.1115.1115.

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Abstract Introduction: Ventricular assist devices (VADs) are increasingly being used in the clinical management of patients with heart failure. While effective, there are risks associated with the use of a VAD. One of the most serious risks is pump thrombosis characterized by an organized fibrin deposition in the pump, which requires clinical intervention and/or surgical replacement of the device. Due to the growing number of cardiac patients with an implanted VAD, it is important to understand the susceptibility to hemostatic dysregulation among these patients to prevent complications. In cur

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O’Day, Steven, Cesar Perez, Trisha Wise-Draper, et al. "423 Safety and preliminary efficacy of intratumoral cavrotolimod (AST-008), a spherical nucleic acid TLR9 agonist, in combination with pembrolizumab in patients with advanced solid tumors." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A449. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0423.

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BackgroundSpherical nucleic acids (SNAs) are nanostructures consisting of radially oriented, densely packed oligonucleotides arranged in a spherical 3D architecture. SNAs have different properties than linear oligonucleotides, including increased cellular uptake, which may enhance efficacy. Cavrotolimod (AST-008) is an SNA toll-like receptor 9 (TLR9) agonist designed to robustly activate innate and adaptive immune responses. Cavrotolimod is in development for the treatment of advanced solid tumors in combination with PD-1 blockade. Prior studies demonstrated that cavrotolimod, alone and in com

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Watanabe, M., K. Nishida, Y. Nasu, et al. "SAT0023 THE ROLE OF ADAM12 UPREGULATED PROLIFERATION OF SYNOVIAL MEMBRANE IN RHEUMATOID ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 941.2–942. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1968.

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Background:ADAM12 is a member of a disintegrin and metalloproteinase family and has been reported to participate in the development of a variety of tumors by degrading ECM and shed precursors, thus promoting cell proliferation, invasion, and metastasis1). Additionally, ADAM12 is involved in chondrocyte differentiation from osteoarthritis (OA) patients by regulation of TGFβ1-induced IGF-1 and RUNX-2 expressions2). However, there is no report on the role of ADAM12 for rheumatoid arthritis (RA).Objectives:To investigate the expression and role of ADAM12 in the synovial tissue of RA.Methods:(1) Th

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Hatzistergos, Konstantinos. "Allogeneic Mesenchymal Stem Cells in Cellular Cardiomyoplasty: Mechanisms of Cardiac Repair." Circulation 118, suppl_18 (2008). http://dx.doi.org/10.1161/circ.118.suppl_18.a_20-c.

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Abstract 486 Konstantinos E. Hatzistergos, Henry Quevedo, Behzad N. Oskouei, Qinghua Hu, Ramesh Mazhari, Juan P. Zambrano, David Valdes, Gary S. Feigenbaum, Jose R. Rodriguez, Irene S. Margitich, Jeffrey M. Zimmet, Univ of Miami, Miami, FL; Concepción Revilla, INIA, Madrid, Spain; Alan W. Heldman, Ian McNiece, Joshua M. Hare, Univ of Miami, Miami, FL Konstantinos Hatzistergos, 2008 Finalist and Presenting Author

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Rossi, Fiorella, Hunter Noren, Leonor Sarria, Paul C. Schiller, Lubov Nathanson, and Vladimir Beljanski. "Combination therapies enhance immunoregulatory properties of MIAMI cells." Stem Cell Research & Therapy 10, no. 1 (2019). http://dx.doi.org/10.1186/s13287-019-1515-3.

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Abstract Background Mesenchymal stromal cells (MSCs), adult stromal cells most commonly isolated from bone marrow (BM), are being increasingly utilized in various therapeutic applications including tissue repair via immunomodulation, which is recognized as one of their most relevant mechanism of action. The promise of MSC-based therapies is somewhat hindered by their apparent modest clinical benefits, highlighting the need for approaches that would increase the efficacy of such therapies. Manipulation of cellular stress-response mechanism(s) such as autophagy, a catabolic stress-response mecha

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Rubin, Ewelina T., Ian C. Enochs, Colin Foord, et al. "Molecular Mechanisms of Coral Persistence Within Highly Urbanized Locations in the Port of Miami, Florida." Frontiers in Marine Science 8 (July 20, 2021). http://dx.doi.org/10.3389/fmars.2021.695236.

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Healthy coral communities can be found on artificial structures (concrete walls and riprap) within the Port of Miami (PoM), Florida. These communities feature an unusually high abundance of brain corals, which have almost entirely vanished from nearby offshore reefs. These corals appear to be thriving in very low-quality waters influenced by dense ship and boat traffic, dredging, and numerous residential and industrial developments. The PoM basin is part of Biscayne Bay, an estuarine environment that experiences frequent freshwater input, high nutrient loading, hypoxia, and acidification. To i

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Shibata, Kazuhiko, Hirokazu Morita, Mitsutaka Ueda, and Shigeru Nakai. "P1364CATIONIC CELLULOSE BASED PAD STOPS BLEEDING WITHIN FIVE MINUTES AFTER HEMODIALYSIS." Nephrology Dialysis Transplantation 35, Supplement_3 (2020). http://dx.doi.org/10.1093/ndt/gfaa142.p1364.

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Abstract Background and Aims In case of prolonged bleeding at the vascular access site after hemodialysis, a nurse must compress the bleeding site longer than usual. This situation causes the risk of intravascular thrombosis and consumes valuable time of both patients and staff. Therefore, the method that can surely stop bleeding from the puncture site in short time is desired. Nowadays, chitosan is considered as one of the strongest hemostatic substance. Nipro Corporation and Artisan-lab co.,Ltd found the cationic cellulose could clot blood faster than chitosan in the activated clotting time

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"The 15th Annual Meeting of the Summer Neuropeptide Conference, Miami Beach, Florida, USA, July 5–9, 2005." Neuropeptides 40, no. 2 (2006): 133–36. http://dx.doi.org/10.1016/j.npep.2005.11.003.

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"Molecular approaches to the study of the function of cardiac and skeletal muscle troponin I James D. Potter, Zelin Sheng, Ren Zhang, Bo-Sheng Pan and Todd Miller. Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, Miami, Florida 33101." Journal of Molecular and Cellular Cardiology 24 (July 1992): 26. http://dx.doi.org/10.1016/0022-2828(92)93419-k.

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"Abstracts from the Summer Neuropeptide Conference: The 14th Annual Meeting of the Summer Neuropeptide Conference, Miami Beach, Florida, USA, July 5–9, 2004." Neuropeptides 39, no. 1 (2005): 35–65. http://dx.doi.org/10.1016/j.npep.2004.09.002.

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"Abstracts from the Summer Neuropeptide Conference: The 15th Annual Meeting of the Summer Neuropeptide Conference, Miami Beach, Florida, USA, July 5–9, 2005." Neuropeptides 40, no. 2 (2006): 137–59. http://dx.doi.org/10.1016/j.npep.2005.11.004.

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Shibata, Kazuhiko, Shigeru Nakai, Ikuto Masakane, et al. "P1088BRAND NEW METHOD TO CALCULATE THE VOLUME OF EXTRA CELLULAR FLUID IN HEMODIALYSIS PATIENT ONLY FROM REGULAR BLOOD TEST." Nephrology Dialysis Transplantation 35, Supplement_3 (2020). http://dx.doi.org/10.1093/ndt/gfaa142.p1088.

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Abstract Background and Aims Uric acid is a small molecule with molecular weight 168, but has an electrical pole which enables pass through the phospholipid bilayers of cell membranes by simple diffusion. Urate transport proteins of cell membranes (URAT1, GLUT9, OAT, MRP4, MCT9, NPT4, ABCG2) are expressed only in uric acid-excreting tissues. These findings suggest that uric acid does not pass through the cell membrane, either by diffusion or active transport. Since uric acid does not pass through cell membranes, the uric acid distribution volume (UDiV) would reflect the extracellular volume (E

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Hunter, John C. "Organic Interfaces; or, How Human Beings Augment Their Digital Devices." M/C Journal 16, no. 6 (2013). http://dx.doi.org/10.5204/mcj.743.

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In many ways, computers are becoming invisible and will continue to do so. When we reach into our pockets and pull out our cell phones to find a place to eat or message a friend on Facebook, we are no longer consciously aware that we are interacting with a user experience that has been consciously designed for our computer or device screen—but we are.— Andy Pratt and Jason Nunes, Interactive Design In theory, cell phones and other information and communication technologies (ICTs) are just a means for us to interact with people, businesses, and data sources. They have interfaces and, in a large

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Deer, Patrick, and Toby Miller. "A Day That Will Live In … ?" M/C Journal 5, no. 1 (2002). http://dx.doi.org/10.5204/mcj.1938.

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By the time you read this, it will be wrong. Things seemed to be moving so fast in these first days after airplanes crashed into the World Trade Center, the Pentagon, and the Pennsylvania earth. Each certainty is as carelessly dropped as it was once carelessly assumed. The sounds of lower Manhattan that used to serve as white noise for residentsâ€”sirens, screeches, screamsâ€”are no longer signs without a referent. Instead, they make folks stare and stop, hurry and hustle, wondering whether the noises we know so well are in fact, this time, coefficients of a new reality. At the time of writing

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