Готові списки джерел за темами / Endocrine aspects of Immunity / Статті в журналах
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Статті в журналах з теми "Endocrine aspects of Immunity"

Автор: Grafiati
Опубліковано: 4 червня 2021
Оновлено: 7 лютого 2022

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1

Adriana, Gherbon. "Aspects of Humoral Immunity in a Group of Children With Type 1 Diabetes and Thyroid Disorders." European Scientific Journal, ESJ 12, no. 36 (December 31, 2016): 18. http://dx.doi.org/10.19044/esj.2016.v12n36p18.

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Анотація:
Patients with diabetes have a high prevalence of thyroid disease compared with non-diabetic population. In the case of type 1 diabetes, it is often associated with autoimmune endocrine and systemic diseases as: Graves-Basedow disease, autoimmune chonic thyroiditis (ACT), Addison's disease, celiac disease, pernicious anemia, myasthenia gravis, vitiligo, etc.. The purpose of this study is to determine the main aspects of humoral immunity in a group of children with type 1 diabetes and thyroid disorders. The studied group was represented by 83 cases (71 girls and 12 boys), aged between 7-17 years. They were used clinical, imaging, biochemical, hormonal and immunological parameters. Results: Prevalence of positive anthyroid antibodies (ACAT) in the study group was: Basedow – Graves disease – 100% (both), ACT - 85.18% antiTPO and 83.33% antiTg, euthyroid difusse goiter – 0% (both). In the case of children and adolescents with type 1 diabetes and ACT with positive antiTPO AB we notice that they had a younger onset age of diabetes (4.86 ± 3.94 vs. 8.62 ± 0.51 years), a longer duration of diabetes (9.23 ± 4.05 vs. 8.12 ± 0.64 years), elevated HbA1c values (8.91 ± 2.03 vs.7, 55 ± 1.96%) and lower TSH values (12.00 ± 23.7 vs. 14.77 ± 17.03 mIU/ml) than those negative. Conclusions: It is recommended determination of antithyroid antibodies, particularly those antiTPO in children and adolescents with type 1 diabetes at onset of diabetes, or before puberty and, if they are positive should be tested the thyroid function annually to minimize the risk of undiagnosed hypothyroidism.
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2

Zhelavskyi, M. M. "Immunobiological aspects of cow lactation." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 21, no. 95 (November 2, 2019): 3–8. http://dx.doi.org/10.32718/nvlvet9501.

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Lactation of cows is a high-energy metabolic process. It is regulated in the body by the complex physiological mechanisms of the nervous, endocrine and immune systems. The purpose of to study changes in the immunobiological reactivity of the body of cows during lactation. Clinical and experimental studies were accomplished at the veterinary clinic and in the specialized laboratory of reproductive animal immunology. For the study, four groups of analogues of experimental animals were formed in which the immunological methods determined the immune status: cows (n = 17) during the early lactation (secretion of colostrum, 3–5th day); second (n = 32) – cows (n = 32) in the mid (3–5th month) lactation; the third (n = 28) – during the late lactation (5–7th day) and the fourth group (n = 28) – during the dry period (12–20th day). Our research has shown that during lactation in the body of cows fluctuations of the studied indicators of cellular and humoral immunity occur. Experimental data that showed that the percentage of T-lymphocytes in the blood of cows of Ukrainian dairy black-billed breed during the initial (3–5 days) period of lactogenesis is the lowest (37.88 ± 1.53%). However, the lowest expression of B-immune cells (16.05 ± 0.74%) was also detected during colostrum secretion. These changes occurred against the background of the decrease in CD3+/СD22+ (2.36 ± 0.11). In particular, at the 3–5th month of lactation, peripheral blood flow contained 53.40 ± 0.83% CD3+, ie 1.40 times more. The number of CD22+ mononuclear cells increased by only 1.14 times (up to 18.31 ± 0.69%). The beginning late lactation and dry period in the number of immunocompetent cells was observed: CD3+ – up to 42.11 ± 1.03%, and CD22+ – up to 22.92 ± 0.89%. All this was accompanied by a corresponding redistribution of the balance (CD3+/СD22+). We have identified certain patterns in the blast transformation ability of T-lymphocytes, which was manifested in the change in the activity of activated immune cells of blood. At the beginning of lactation, the functional capacity of T cells was the lowest (42.47 ± 0.62%). But subsequently with the increase of the lactation curve there was a certain activation of their transformation into blasts (51.11 ± 1.05%). At the beginning of late lactation cows underwent a gradual decrease in the blasttransformation capacity of immunocompetent cells (43.11 ± 0.89%). And which continued to decline gradually during the dry period. Thus, during lactation in the body of cows there are dynamic permanent changes in the system of cellular and humoral immunity. From the beginning of lactogenesis, there is a gradual increase in the increase in the functioning of the mammary gland of cows, and further decrease in the population composition of CD3+ and СD22+, which was also accompanied by changes in the functional activity of immunocompetent cells.
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3

Tang, Tian, Jinghan Yang, and Siyuan Jing. "A Preliminary Study on the Mechanism of Premature Ovarian Failure." Proceedings of Anticancer Research 5, no. 4 (July 29, 2021): 34–39. http://dx.doi.org/10.26689/par.v5i4.2318.

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Premature ovarian failure (POF) refers to the failure of ovaries which causes amenorrhea before the age of 40. It is characterized by primary or secondary amenorrhea along with elevated blood gonadotropin levels and decreased estrogen levels with varying degrees of low estrogen symptoms such as hot flashes and sweating, facial flushing, reduced libido, and so on. Premature ovarian failure (POF) is a common endocrine disease in gynecology. The incidence of POF is increasing year by year and the affected population increasingly involves the younger-aged groups. Its etiology is complex and diverse involving many factors such as genetics, immunity, medical treatment, environment endocrine disruptors, etc. It is also affected by long-term smoking, alcohol intake, and other behaviors which damage patients’ physical and mental health. In recent years, the effects of gene therapy in restoring ovarian function and improving fertility in animal experiments have provided a new direction for POF patients. This article discusses the etiology and possible pathogenesis of POF and BRCA from various aspects as well as summarizes the recent research status and progress of new treatment methods of POF.
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4

Meier, Ursula, and Axel M. Gressner. "Endocrine Regulation of Energy Metabolism: Review of Pathobiochemical and Clinical Chemical Aspects of Leptin, Ghrelin, Adiponectin, and Resistin." Clinical Chemistry 50, no. 9 (September 1, 2004): 1511–25. http://dx.doi.org/10.1373/clinchem.2004.032482.

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Abstract Background: Recent studies point to the adipose tissue as a highly active endocrine organ secreting a range of hormones. Leptin, ghrelin, adiponectin, and resistin are considered to take part in the regulation of energy metabolism. Approach: This review summarizes recent knowledge on leptin and its receptor and on ghrelin, adiponectin, and resistin, and emphasizes their roles in pathobiochemistry and clinical chemistry. Content: Leptin, adiponectin, and resistin are produced by the adipose tissue. The protein leptin, a satiety hormone, regulates appetite and energy balance of the body. Adiponectin could suppress the development of atherosclerosis and liver fibrosis and might play a role as an antiinflammatory hormone. Increased resistin concentrations might cause insulin resistance and thus could link obesity with type II diabetes. Ghrelin is produced in the stomach. In addition to its role in long-term regulation of energy metabolism, it is involved in the short-term regulation of feeding. These hormones have important roles in energy homeostasis, glucose and lipid metabolism, reproduction, cardiovascular function, and immunity. They directly influence other organ systems, including the brain, liver, and skeletal muscle, and are significantly regulated by nutritional status. This newly discovered secretory function has extended the biological relevance of adipose tissue, which is no longer considered as only an energy storage site. Summary: The functional roles, structures, synthesis, analytical aspects, and clinical significance of leptin, ghrelin, adiponectin, and resistin are summarized.
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5

Torino, Francesco, Agnese Barnabei, Rosa Maria Paragliola, Paolo Marchetti, Roberto Salvatori, and Salvatore Maria Corsello. "ENDOCRINE SIDE-EFFECTS OF ANTI-CANCER DRUGS: mAbs and pituitary dysfunction: clinical evidence and pathogenic hypotheses." European Journal of Endocrinology 169, no. 6 (December 2013): R153—R164. http://dx.doi.org/10.1530/eje-13-0434.

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mAbs are established targeted therapies for several diseases, including hematological and solid malignancies. These agents have shown a favorable toxicity profile, but, despite their high selectivity, new typical side-effects have emerged. In cancer patients, pituitary dysfunction may be mainly due to brain metastases or primary tumors and to related surgery and radiotherapy. Anticancer agents may induce hypopituitarism in patients cured for childhood cancers. These agents infrequently affect pituitary function in adult cancer patients. Notably, hypophysitis, a previously very rare disease, has emerged as a distinctive side-effect of ipilimumab and tremelimumab, two mAbs inhibiting the cytotoxic T-lymphocyte antigen-4 receptor, being occasionally seen with nivolumab, another immune checkpoint inhibitor. Enhanced antitumor immunity is the suggested mechanism of action of these drugs and autoimmunity the presumptive mechanism of their toxicity. Recently, ipilimumab has been licensed for the treatment of patients affected by metastatic melanoma. With the expanding use of these drugs, hypophysitis will be progressively encountered by oncologists and endocrinologists in clinical practice. The optimal management of this potentially life-threatening adverse event needs a rapid and timely diagnostic and therapeutic intervention. Hypopituitarism caused by these agents is rarely reversible, requiring prolonged or lifelong substitutive hormonal treatment. Further studies are needed to clarify several clinical and pathogenic aspects of this new form of secondary pituitary dysfunction.
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6

Zhao, Hongyan, Ning Zhao, Peng Zheng, Xiaohong Xu, Meijie Liu, Dan Luo, Huihui Xu, and Dahong Ju. "Prevention and Treatment of Osteoporosis Using Chinese Medicinal Plants: Special Emphasis on Mechanisms of Immune Modulation." Journal of Immunology Research 2018 (2018): 1–11. http://dx.doi.org/10.1155/2018/6345857.

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Numerous studies have examined the pathogenesis of osteoporosis. The causes of osteoporosis include endocrine factors, nutritional status, genetic factors, physical factors, and immune factors. Recent osteoimmunology studies demonstrated that the immune system and immune factors play important regulatory roles in the occurrence of osteoporosis, and people should pay more attention to the relationship between immunity and osteoporosis. Immune and bone cells are located in the bone marrow and share numerous regulatory molecules, signaling molecules, and transcription factors. Abnormal activation of the immune system alters the balance between osteoblasts and osteoclasts, which results in an imbalance of bone remodeling and osteoporosis. The incidence of osteoporosis is also increasing with the aging of China’s population, and traditional Chinese medicine has played a vital role in the prevention and treatment of osteoporosis for centuries. Chinese medicinal plants possess unique advantages in the regulation of the immune system and the relationships between osteoporosis and the immune system. In this review, we provide a general overview of Chinese medicinal plants in the prevention and treatment of osteoporosis, focusing on immunological aspects.
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7

Srinivasan, N., V. Swarnapriya, A. J. W. Felix, and T. Pravin. "Assessment of knowledge and practice on plastics among the professional course students of Annamalai University, Tamil Nadu." International Journal Of Community Medicine And Public Health 6, no. 2 (January 24, 2019): 510. http://dx.doi.org/10.18203/2394-6040.ijcmph20190099.

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Background: The use of plastics made life easy in day to day life. However, the disposal of it remains a public health problem worldwide. Plastic waste are major cause of environment pollution becomes carcinogenic to human, birth defects, impaired immunity, endocrine disruption, development and reproductive effect. Raising the awareness of the different stake holders is suggested by United Nations Environment Programme. Assessing the knowledge and practice of the student community, especially of the professional courses, in this regard is considered as a vital one.Methods: A total of 563 students of professional courses were included in the study. Their knowledge in terms general aspects, ill effects, reuse and practice in terms of usage and disposal were assessed with a questionnaire.Results: 46% of the students found having good knowledge. Only 27.6% were found to have good practice. Though the students have good knowledge on ill effects of plastics, their practice in terms of disposal was less. Significant variations were observed among the students of different courses.Conclusions: Addressing the gap between knowledge and practice in terms of designing messages for proper disposal and avoiding usage of single use plastics at individual and collective level is required.
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8

Tilg, Herbert, and Alexander R. Moschen. "Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases." Clinical Science 114, no. 4 (January 15, 2008): 275–88. http://dx.doi.org/10.1042/cs20070196.

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Анотація:
Obesity and obesity-related disorders play an important role in clinical medicine. Adipose tissue, with its soluble mediators called adipocytokines, has emerged as a major endocrine organ. These adipocytokines comprise many mediators such as adiponectin, PBEF (pre-B-cell-enhancing factor)/visfatin, leptin, resistin, retinol-binding protein-4 and others. They play major roles in key aspects of metabolism, such as insulin resistance, fatty acid oxidation, inflammation and immunity. Adiponectin, a prototypic adipocytokine, is of importance in the regulation of insulin resistance, as circulating levels are decreased in obesity and diseases associated with insulin resistance. Besides its major role in regulation of insulin sensitivity, recent evidence suggests potent anti-inflammatory functions for adiponectin. These effects are paralleled by other immune-regulatory properties, such as regulation of endothelial cell function. The in vitro effects of adiponectin have been corroborated by several studies demonstrating potent in vivo anti-inflammatory effects. Many other adipocytokines, such as PBEF/visfatin, leptin, resistin or retinol binding protein-4, are involved in the physiology and pathophysiology of adipocytes, adipose tissue and related diseases. PBEF/visfatin, another recently characterized adipocytokine, has been linked to several inflammatory disease states beyond insulin resistance, such as acute lung injury or inflammatory bowel diseases. It has been recognized for many decades that obesity is accompanied by an increase in cancer and potentially some immune-mediated diseases. Understanding this new exciting world of adipocytokines will be of importance in the development of novel therapies for obesity-associated diseases.
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9

Falzoni, Simonetta, Giovanna Donvito, and Francesco Di Virgilio. "Detecting adenosine triphosphate in the pericellular space." Interface Focus 3, no. 3 (June 6, 2013): 20120101. http://dx.doi.org/10.1098/rsfs.2012.0101.

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Release of adenosine triphosphate (ATP) into the extracellular space occurs in response to a multiplicity of physiological and pathological stimuli in virtually all cells and tissues. A role for extracellular ATP has been identified in processes as different as neurotransmission, endocrine and exocrine secretion, smooth muscle contraction, bone metabolism, cell proliferation, immunity and inflammation. However, ATP measurement in the extracellular space has proved a daunting task until recently. To tackle this challenge, some years ago, we designed and engineered a novel luciferase probe targeted to and expressed on the outer aspect of the plasma membrane. This novel probe was constructed by appending to firefly luciferase the N-terminal leader sequence and the C-terminal glycophosphatidylinositol anchor of the folate receptor. This chimeric protein, named plasma membrane luciferase, is targeted and localized to the outer side of the plasma membrane. With this probe, we have generated stably transfected HEK293 cell clones that act as an in vitro and in vivo sensor of the extracellular ATP concentration in several disease conditions, such as experimentally induced tumours and inflammation.
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10

Greco, Deborah S., and Lynn M. Harpold. "Immunity and the Endocrine System." Veterinary Clinics of North America: Small Animal Practice 24, no. 4 (July 1994): 765–82. http://dx.doi.org/10.1016/s0195-5616(94)50083-4.

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11

Khardori, Romesh, Alys Adamski, and Nancy Khardori. "Infection, Immunity, and Hormones/Endocrine Interactions." Infectious Disease Clinics of North America 21, no. 3 (September 2007): 601–15. http://dx.doi.org/10.1016/j.idc.2007.06.002.

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12

Proietto, Joseph. "Endocrine aspects of obesity." Molecular and Cellular Endocrinology 316, no. 2 (March 2010): 103. http://dx.doi.org/10.1016/j.mce.2009.12.004.

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13

Glass, Allan R. "Endocrine Aspects of Obesity." Medical Clinics of North America 73, no. 1 (January 1989): 139–60. http://dx.doi.org/10.1016/s0025-7125(16)30696-4.

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14

Sica, G. "Pathophysiologic and Endocrine Aspects." Journal of International Medical Research 18, no. 1_suppl (January 1990): 8–10. http://dx.doi.org/10.1177/03000605900180s103.

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15

KALTENBACH, JANE C. "Endocrine Aspects of Homeostasis." American Zoologist 28, no. 2 (May 1988): 761–73. http://dx.doi.org/10.1093/icb/28.2.761.

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16

Shalet, SM. "Endocrine aspects of cancer." British Journal of Cancer 70, no. 3 (September 1994): 569. http://dx.doi.org/10.1038/bjc.1994.347.

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17

Drent, M. "Endocrine aspects of obesity." Netherlands Journal of Medicine 47, no. 3 (September 1995): 127–36. http://dx.doi.org/10.1016/0300-2977(95)00008-b.

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18

Vagenakis, A. G. "Endocrine aspects of menopause." Clinical Rheumatology 8, S2 (June 1989): 48–51. http://dx.doi.org/10.1007/bf02207233.

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19

Murialdo, G., and G. Tamagno. "Endocrine aspects of neurosarcoidosis." Journal of Endocrinological Investigation 25, no. 7 (July 2002): 650–62. http://dx.doi.org/10.1007/bf03345093.

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20

Deem, Michael W., and Pooya Hejazi. "Theoretical Aspects of Immunity." Annual Review of Chemical and Biomolecular Engineering 1, no. 1 (June 15, 2010): 247–76. http://dx.doi.org/10.1146/annurev-chembioeng-073009-100952.

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21

Ilić, Saša, Draško Gostiljac, Vesna Dimitrijević-Srećković, and Srđan Popović. "Endocrine aspects of Crohn's disease." Medicinski glasnik Specijalne bolnice za bolesti štitaste žlezde i bolesti metabolizma 24, no. 74 (2019): 7–18. http://dx.doi.org/10.5937/medgla1973007i.

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22

Sonino, N., J. Guidi, and GA Fava. "Psychological aspects of endocrine disease." Journal of the Royal College of Physicians of Edinburgh 45, no. 1 (2015): 55–59. http://dx.doi.org/10.4997/jrcpe.2015.113.

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23

Yoo, Hyung Joon. "Antiaging Efforts in Endocrine Aspects." Journal of the Korean Medical Association 50, no. 3 (2007): 234. http://dx.doi.org/10.5124/jkma.2007.50.3.234.

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24

Sahin, Ozlem G., Elçin Kartal, and Nusret Taheri. "Meibomian Gland Dysfunction: Endocrine Aspects." ISRN Ophthalmology 2011 (October 20, 2011): 1–6. http://dx.doi.org/10.5402/2011/465198.

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Purpose. To compare the hormone levels of patients with seborrheic meibomian gland dysfunction with controls. Procedures. This is a retrospective case-control study involving 50 patients and 50 controls. Blood workup for hormones was studied in both groups by using macroELISA (enzyme-linked immunosorbent assay). Statistical evaluation was done by using SPSS 15.0 independent samples -test. Results. There were statistically significant differences of serum testosterone and dehydroepiandrosterone sulphate levels between patients and controls (P = 0.000). Female gender showed statistically significant differences of serum thyroid-stimulating hormone and prolactin levels between patients and controls (P = 0.014 and P = 0.043), in addition to serum testosterone and dehydroepiandrosterone sulphate levels (P = 0.000 and P = 0.001). However, male gender showed statistically significant differences of only serum testosterone and dehydroepiandrosterone sulphate levels between patients and controls. (P = 0.003 and P = 0.003 resp.). Conclusions. Increased serum levels of testosterone and dehydroepiandrosterone sulphate in both genders should be considered as diagnostic markers for seborrheic meibomian gland dysfunction.
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25

Hofbauer, Lorenz C., Tilman D. Rachner, Robert E. Coleman, and Franz Jakob. "Endocrine aspects of bone metastases." Lancet Diabetes & Endocrinology 2, no. 6 (June 2014): 500–512. http://dx.doi.org/10.1016/s2213-8587(13)70203-1.

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26

Bravo, Emmanuel L. "Clinical Aspects of Endocrine Hypertension." Medical Clinics of North America 71, no. 5 (September 1987): 907–20. http://dx.doi.org/10.1016/s0025-7125(16)30816-1.

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27

Lizarazo, Adriana Herrera, Michelle McLoughlin, and Maria G. Vogiatzi. "Endocrine aspects of Klinefelter syndrome." Current Opinion in Endocrinology & Diabetes and Obesity 26, no. 1 (February 2019): 60–65. http://dx.doi.org/10.1097/med.0000000000000454.

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28

Higgins, NiallO'. "ENDOCRINE ASPECTS OF BREAST CANCER." ANZ Journal of Surgery 57, no. 10 (October 1987): 697–701. http://dx.doi.org/10.1111/j.1445-2197.1987.tb01246.x.

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29

Wu, F. C. W. "Endocrine aspects of anabolic steroids." Clinical Chemistry 43, no. 7 (July 1, 1997): 1289–92. http://dx.doi.org/10.1093/clinchem/43.7.1289.

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Abstract Understanding of the mechanism of androgen action has been enhanced by advances in knowledge on the molecular basis of activation of the androgen receptor and the importance of tissue conversion of circulating testosterone to dihydrotestosterone and estradiol. New evidence supports the view that supraphysiological doses of anabolic steroids do have a definite, positive effect on muscle size and muscle strength. However, the nature of the anabolic action of androgens on muscle is currently unclear and may involve mechanisms independent of the androgen receptor. The dose–response relationships of anabolic actions vs the potentially serious risks to health of androgenic-anabolic steroids (AAS) use are still unresolved. Most of the adverse effects of AAS are reversible but some are permanent, particularly in women and children. The reported incidence of acute life-threatening events associated with AAS abuse is low, but the actual risk may be underrecognized or underreported; the exact incidence is unknown. The long-term consequences and disease risks of AAS to the sports competitor remain to be properly evaluated.
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30

Currie, Gemma, David M. Carty, John M. Connell, and Marie Freel. "Endocrine aspects of pre-eclampsia." Cardiovascular Endocrinology 4, no. 1 (March 2015): 1–10. http://dx.doi.org/10.1097/xce.0000000000000039.

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31

Pantelakis, Chairmen: S., and CR Rodda. "Endocrine aspects of thalassaemia major." Acta Paediatrica 83, s406 (December 1994): 105–6. http://dx.doi.org/10.1111/j.1651-2227.1994.tb13435.x.

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32

Sonino, Nicoletta, and Giovanni A. Fava. "Psychological aspects of endocrine disease." Clinical Endocrinology 49, no. 1 (July 1998): 1–7. http://dx.doi.org/10.1046/j.1365-2265.1998.00528.x.

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33

Baker, J. R. "Immunologic aspects of endocrine diseases." JAMA: The Journal of the American Medical Association 268, no. 20 (November 25, 1992): 2899–903. http://dx.doi.org/10.1001/jama.268.20.2899.

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34

Beall, Gildon N. "Immunologic Aspects of Endocrine Diseases." JAMA: The Journal of the American Medical Association 258, no. 20 (November 27, 1987): 2952. http://dx.doi.org/10.1001/jama.1987.03400200158019.

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35

Klowden, Marc J. "Endocrine aspects of mosquito reproduction." Archives of Insect Biochemistry and Physiology 35, no. 4 (1997): 491–512. http://dx.doi.org/10.1002/(sici)1520-6327(1997)35:4<491::aid-arch10>3.0.co;2-5.

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36

LIECHTY, R. DALE. "Endocrine Aspects of Acute Illness." Archives of Surgery 120, no. 11 (November 1, 1985): 1327. http://dx.doi.org/10.1001/archsurg.1985.01390350103032.

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37

Beall, G. N. "Immunologic aspects of endocrine diseases." JAMA: The Journal of the American Medical Association 258, no. 20 (November 27, 1987): 2952–56. http://dx.doi.org/10.1001/jama.258.20.2952.

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38

Baker, James R. "Immunologic Aspects of Endocrine Diseases." JAMA: The Journal of the American Medical Association 268, no. 20 (November 25, 1992): 2899. http://dx.doi.org/10.1001/jama.1992.03490200151017.

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39

Akopova, R. A., and T. V. Kokoreva. "ENDOCRINE ASPECTS OF MALE INFERTILITY." Bulletin "Biomedicine and sociology" 3, no. 4 (December 30, 2018): 17–19. http://dx.doi.org/10.26787/nydha-2618-8783-2018-3-4-17-19.

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40

Shalet, S. M. "Endocrine Aspects of Acute Illness." Postgraduate Medical Journal 61, no. 722 (December 1, 1985): 1099. http://dx.doi.org/10.1136/pgmj.61.722.1099.

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41

Franks, Stephen. "Endocrine Aspects of Menstrual Disorders." Medicine 29, no. 11 (November 2001): 34–37. http://dx.doi.org/10.1383/medc.29.11.34.28432.

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42

Müller, B. "Endocrine aspects of critical illness." Annales d'Endocrinologie 68, no. 4 (September 2007): 290–98. http://dx.doi.org/10.1016/j.ando.2007.06.006.

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43

Pervanidou, Panagiota, Evangelia Charmandari, and George P. Chrousos. "Endocrine Aspects of Childhood Obesity." Current Pediatrics Reports 1, no. 2 (February 2, 2013): 109–17. http://dx.doi.org/10.1007/s40124-013-0011-y.

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44

Harrison, Timothy S. "Endocrine aspects of acute illness." American Journal of Surgery 151, no. 5 (May 1986): 639. http://dx.doi.org/10.1016/0002-9610(86)90578-7.

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45

Boehm, B. O., and N. R. Farid. "Molecular aspects of endocrine autoimmunity." Clinical Investigator 71, no. 1 (January 1993): 79–81. http://dx.doi.org/10.1007/bf00210975.

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46

Weetman, A. P. "New Aspects of Thyroid Immunity." Hormone Research 48, no. 4 (1997): 51–54. http://dx.doi.org/10.1159/000191314.

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47

Rehermann, Barbara, and Eui-Cheol Shin. "Private aspects of heterologous immunity." Journal of Experimental Medicine 201, no. 5 (March 7, 2005): 667–70. http://dx.doi.org/10.1084/jem.20050220.

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Анотація:
Clinical manifestations of viral infections are highly variable, both in type and severity, among individual patients. Differences in host genetics and in dose and route of infection contribute to this variability but do not fully explain it. New studies now show that each subject's history of past infections individualizes the memory T cell pool. Private T cell receptor specificities of these preexisting memory T cell populations influence both disease severity and outcome of subsequent, unrelated virus infections.
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48

Harrison, Barney. "Endocrine Surgical Aspects of Multiple Endocrine Neoplasia Syndromes in Children." Hormone Research in Paediatrics 68, no. 5 (2007): 105–6. http://dx.doi.org/10.1159/000110590.

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49

Stover, C., E. Otto, J. Beyer, and G. Kahaly. "Humoral immunity and retrobulbar fibroblasts in endocrine ophthalmopathy." Acta Endocrinologica 126, no. 5 (May 1992): 394–98. http://dx.doi.org/10.1530/acta.0.1260394.

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The exact role of retrobulbar fibroblasts in the immunopathogenesis of endocrine ophthalmopathy still remains to be elucidated. To evaluate the in vitro influence of humoral immunity on retrobulbar fibroblasts, the effects of immunoglobulin G as well as of the sera of 50 euthyroid patients with endocrine ophthalmopathy and 30 controls on both porcine and human (patients' and controls') retrobulbar fibroblasts were measured by means of several assays: a colorimetric test involving a heterocyclic chemical, a tetrazolium bromide, was applied to quantify the activity of mitochondrial dehydrogenases; the incorporation of 3H-thymidine was determined as a sensitive parameter for cell proliferation, and an enzyme-linked immunosorbent assay was to reveal specific binding of antibodies to the cells. There was consistently no significant difference between patients' (untreated or treated) and controls' IgG to bind to, to activate or to stimulate the proliferation of porcine and human (patients and controls) retrobulbar fibroblasts. The effects of patients' heat-inactivated and non-inactivated sera were indistinguishable from those of the controls. Incubation of autologous sera, however, led to an activation of retrobulbar fibroblasts which was both higher than the median caused by the patients' group and that engendered by incubation of autologous IgG. Yet, a significant role that humoral immunity might play directly on retrobulbar fibroblasts could not be detected in the experiments conducted in this study.
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Nappi, Francesca, Luigi Barrea, Carolina Di Somma, Maria Savanelli, Giovanna Muscogiuri, Francesco Orio, and Silvia Savastano. "Endocrine Aspects of Environmental “Obesogen” Pollutants." International Journal of Environmental Research and Public Health 13, no. 8 (July 28, 2016): 765. http://dx.doi.org/10.3390/ijerph13080765.

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