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Dissertations / Theses on the topic '2-Formyl'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Bena, Stefania. "Expression and function of the formyl peptide receptor 2 in experimental myocardial infarct." Thesis, Queen Mary, University of London, 2014. http://qmro.qmul.ac.uk/xmlui/handle/123456789/7905.

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In Acute Myocardial Infarction (AMI), inflammation is a prerequisite for healing but it can paradoxically extend tissue injury; hence it needs to be modulated. Here, we investigated the role of the pro resolving GPCR FPR2/ALX and its agonist Annexin A1 (AnxA1) in AMI using mice lacking of the Fpr2/3 genes and with an in-frame GFP gene ‘knocked-in’. We developed protocols aimed to determine GFP expression as an indication of Fpr2 gene activity. Also, the Left Anterior Descending Coronary Artery of male Fpr2/3 KO and littermate controls (WT) was occluded for 30min and re-opened for 90min. At the

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2

Smith, Helen Katherine. "Resolving inflammation after stroke through modulation of Formyl Peptide Receptor 2, the lipoxin receptor." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/39362.

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Stroke kills 15 million people a year and causes disabilities in many more millions who survive. Most strokes are caused by a blood clot, yet only seven percent of patients qualify for early pharmacological clot removal. Damage is frequently exacerbated even as blood reperfuses an ischaemic brain region, through a concomitant inflammatory response to the damaged tissue. Following the continual failure in clinical trials of drugs intended to tackle both initial excitotoxic cell death and pro-inflammatory mechanisms during ischaemia/reperfusion (I/R), this thesis is premised on enhancing 'pro-re

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3

Augner, Daniel [Verfasser]. "Modulare Synthese von Isoindolinonen aus 2-Formyl-arylketonen und Anwendungen in der Wirk- und Naturstoffchemie / Daniel Augner." München : Verlag Dr. Hut, 2014. http://d-nb.info/1059330202/34.

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4

Winkler, Ralf. "Reaktionen am 2-Formyl-1,6-Methanoannulen : Synthesen und Eigenschaften ethinylierter und trimethylsilylethinylierter Molekülsysteme mit 1,6-Methano[10]annulen-Partialstruktur /." [S.l. : s.n.], 1990. http://www.gbv.de/dms/bs/toc/025245899.pdf.

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5

Neymeyer, Hanna. "Annexin A1 im chronischen Nierenversagen." Phd thesis, Universität Potsdam, 2013. http://opus.kobv.de/ubp/volltexte/2014/6967/.

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Die Expansion des renalen Tubulointerstitiums aufgrund einer Akkumulation zellulärer Bestandteile und extrazellulärer Matrix ist eine charakteristische Eigenschaft der chronischen Nierenerkrankung (CKD) und führt zu einer Progression der Erkrankung in Richtung eines terminalen Nierenversagens. Die Fibroblasten Proliferation und ihre Transformation hin zum sekretorischen Myofibroblasten-Phänotyp stellen hierbei Schlüsselereignisse dar. Signalprozesse, die zur Induktion der Myofibroblasten führen, werden aktiv beforscht um anti-fibrotische Therapieansätze zu identifizieren. Das anti-inflammatori

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6

Krishna, Prasad Golla. "Synthesis of multicyclic 2-pyridones from a formyl and chlorometylene substituted precursor using a strategy of directed diversity-oriented synthesis." Thesis, Umeå universitet, Kemiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-56763.

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Multi ring-fused 2-pyridones have shown interesting activity in a variety of biological systems. It would be of great interest to explore the biological application of even more multi heterocyclic ring fused 2-pyridones. ‘Diversity oriented synthesis’ is an excellent concept emerged in recent years to access compounds with structurally and stereochemically diverse skeletons. This served as an efficient avenue for synthesizing various ring fused 2-pyridones using formyl, chloromethylene substituted 2-pyridone ( 6) as a starting compound. By treating the starting material (6) with various nucleo

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7

Sevastyanova, Olena. "On the importance of oxidizable structures in bleached kraft pulps." Doctoral thesis, KTH, Fiber- och polymerteknik, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-534.

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After cooking, kraft pulps always contain not only residual lignin but also significant amounts of hexenuronic acid and other non-lignin structures oxidizable by permanganate under the standard kappa number determination conditions. These here referred to as false lignin. Like ordinary lignin, the false lignin also consumes bleaching chemicals, thus increasing both the production costs and the environmental impact of bleach plant effluents. The false lignin also has an effect on pulp properties such as brightness stability. This necessitates the development of efficient experimental routines f

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8

Berndt, Christian. "Bildungstendenz und Reaktionen von α-Azidoalkoholen". Doctoral thesis, Universitätsbibliothek Chemnitz, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-112553.

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Gegenstand der vorliegenden Arbeit ist die Synthese von α-Azidoalkoholen durch die Reaktion von aliphatischen sowie aromatischen Aldehyden mit Stickstoffwasserstoffsäure. Dabei stellt sich ein Gleichgewicht ein, dessen Lage durch die Ermittlung der Gleichgewichtskonstanten quantitativ bestimmt wird. In jedem Fall besteht die Möglichkeit, den α-Azidoalkohol in der Gleichgewichtsmischung zu charakterisieren und teilweise gelingt die Isolierung der reinen α-Azidoalkohole bei tiefen Temperaturen sowie deren Charakterisierung mittels Tieftemperatur-NMR-Spektroskopie. Die Ausgangsaldehyde für die Sy

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9

Chou, Tsung Hsien, and 周宗賢. "(1)Pyrolytic study of 2-chloroformyl-3-methylfuran and 3-chloro formyl-2-methylfuran;(2)Pyrolytic study of 2,5-di(benzoyloxymet hyl)furan." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/09492641374684368818.

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10

Liu, Po-Lin, and 劉柏麟. "One-pot Synthesis of 6-[(Formyl)methyl]-1H-pyrazolo[3,4-d]pyrimidines from 5-(2-Chloroacetylamino)pyrazoles and Bioactivity Study." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/nfamc8.

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碩士<br>中國醫藥大學<br>藥物化學研究所碩士班<br>102<br>A new one-pot multicomponent reaction was successfully developed as a key strategy for the synthesis of 6-[(formyl)methyl]-1H-pyrazolo[3,4-d]- pyrimidine compounds from 5-(2-chloroacetylamino)pyrazoles with formamide in presence of PBr3. Under the reliable condition, the tandem multicomponent reactions involving Vilsmeier-Haack reaction, Morgan-Walls reaction, sequential elimination, substitution reaction, and final hydrolysis reaction efficiently afforded formylmethylpyrazolo[3,4-d]pyrimidine products in good yields (73–92%).

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11

Ling-Chu and 張玲菊. "The mechanisms of inhibition by LCY-2-CHO of lipopolysaccharide-stimulated nitric oxide production in N9 microglia and by CHS-111 of formyl peptide-induced superoxide anion generation in rat neutrophils." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/76255994979577404172.

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博士<br>中山醫學大學<br>醫學研究所<br>97<br>1. Excessive nitric oxide (NO) production by activated microglia plays a critical role in neurodegenerative disorders. In this study, we found that 9-(2-chlorobenyl)-9H-carbazole-3-carbaldehyde (LCY-2-CHO) suppressed the NO production in lipopolysaccharide (LPS)/interferon-gamma (IFNg)-stimulated murine microglial N9 cell and in LPS-stimulated N9 cells, BV-2 cells and rat primary microglia. LCY-2-CHO had no cytotoxic effect on microglia. In activated N9 cells, LCY-2-CHO abolished the expression of inducible nitric oxide synthase (iNOS) protein and mRNA but failed

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12

Fousová, Eva. "Organizované formy volnočasových aktivit dětí 2.stupně ZŠ v Ostrově." Master's thesis, 2010. http://www.nusl.cz/ntk/nusl-298926.

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Title: Organized Forms of Pupils` Leisure Time Physical Activities at the second grade of Primary School in Ostrov. Objectives: The aim of this Master`s Thesis is to survey the organization which offers physical activities to the students in Ostrov and their range of sports clubs. Using questionnaires, I want to find out how much students in Ostrov (6th and 9th class of elementary school) are interested in sports offered by different organizations. Methods: This master`s thesis have an empirical character. The qualitative research is used according to the surveying in Ostrov's sports organizat

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13

Pintérová, Daniela. "Molekulární aspekty genetické predispozice k diabetes mellitus 2. typu a jeho monogenní formy." Doctoral thesis, 2009. http://www.nusl.cz/ntk/nusl-278680.

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The aim of this work was to study some molecular aspects of genetic predisposition to T2DM and its monogenic forms. We searched for correlations of genotypes with many clinical and laboratory markers and tried to evaluate their significance. The consequences for possible changes in the treatment some particular patients were under discussion. Especially for those suffering from monogenic forms we were able to reach better compensation of DM, or at latest the same compensation for more acceptable therapy. We studied the associations of chosen candidate genes, PPAR, NF-B, its inhibitor IB, known

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14

Berndt, Christian. "Bildungstendenz und Reaktionen von α-Azidoalkoholen". Doctoral thesis, 2012. https://monarch.qucosa.de/id/qucosa%3A19875.

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Gegenstand der vorliegenden Arbeit ist die Synthese von α-Azidoalkoholen durch die Reaktion von aliphatischen sowie aromatischen Aldehyden mit Stickstoffwasserstoffsäure. Dabei stellt sich ein Gleichgewicht ein, dessen Lage durch die Ermittlung der Gleichgewichtskonstanten quantitativ bestimmt wird. In jedem Fall besteht die Möglichkeit, den α-Azidoalkohol in der Gleichgewichtsmischung zu charakterisieren und teilweise gelingt die Isolierung der reinen α-Azidoalkohole bei tiefen Temperaturen sowie deren Charakterisierung mittels Tieftemperatur-NMR-Spektroskopie. Die Ausgangsaldehyde für die Sy

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15

SEDMÍKOVÁ, Kristýna. "Otázka čtenářského kánonu a formy recepce v literárním vzdělávání na 2. stupni ZŠ (se zaměřením na tvorbu K. H. Máchy a B. Němcové)." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-375732.

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The work will focus on the issue of the Czech literary canon and the literary legacy as a national wealth, while the work will focus especially the reception of this legacy in pupils at the elementary school. For this purpose, two authors were chosen - Karel Hynek Mácha and Božena Němcová. They are canonical authors their works were in many ways pioneering and determined for the subsequent development of Czech literature. The thesis is asking the extent to which importance is attached to these writers in the eyes of elementary school pupils. The work highlights the different perceptions of key

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16

Dvořáková, Dita. "Sebehodnocení žáků při přestupu z 1. na 2. stupeň základní školy." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-328075.

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The topic of my graduation final thesis is "Pupils self-evaluation during the children transfer from 1. to 2. level of a primary school (and teachers help with determining self-evaluation criteria). The thesis is composed as theoretical - empirical work. The mail goal of the theoretical part of my final thesis is to define main terms of pupils self-evaluation during the evaluating criteria formation and teachers help with determining self-evaluation criteria using didactical and psychological literature. The main goal of the empirical part of my final thesis is to map the occurrence of self- e

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