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Journal articles on the topic '4-aminophenazone'

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Published: 5 June 2025

Last updated: 1 August 2025

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1

Khurshid, Asma, Aamer Saeed, Tuncer Hökelek, et al. "Experimental and Hirshfeld Surface Investigations for Unexpected Aminophenazone Cocrystal Formation under Thiourea Reaction Conditions via Possible Enamine Assisted Rearrangement." Crystals 12, no. 5 (2022): 608. http://dx.doi.org/10.3390/cryst12050608.

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Considering the astounding biomedicine properties of pharmaceutically active drug, 4-aminophenazone, also known as 4-aminoantipyrine, the work reported in this manuscript details the formation of novel cocrystals of rearranged 4-aminophenazone and 4-nitro-N-(4-nitrobenzoyl) benzamide in 1:1 stoichiometry under employed conditions for thiourea synthesis by exploiting the use of its active amino component. However, detailed analysis via various characterization techniques such as FT-IR, nuclear magnetic resonance spectroscopy and single crystal XRD, for this unforeseen, but useful cocrystalline

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2

Khurshid, Asma, Aamer Saeed, Tuncer Hökelek, et al. "Experimental and Hirshfeld Surface Investigations for Unexpected Aminophenazone Cocrystal Formation under Thiourea Reaction Conditions via Possible Enamine Assisted Rearrangement." Crystals 12, no. 5 (2022): 608. http://dx.doi.org/10.3390/cryst12050608.

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Considering the astounding biomedicine properties of pharmaceutically active drug, 4-aminophenazone, also known as 4-aminoantipyrine, the work reported in this manuscript details the formation of novel cocrystals of rearranged 4-aminophenazone and 4-nitro-N-(4-nitrobenzoyl) benzamide in 1:1 stoichiometry under employed conditions for thiourea synthesis by exploiting the use of its active amino component. However, detailed analysis via various characterization techniques such as FT-IR, nuclear magnetic resonance spectroscopy and single crystal XRD, for this unforeseen, but useful cocrystalline

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3

Khurshid, Asma, Aamer Saeed, Tuncer Hökelek, et al. "Experimental and Hirshfeld Surface Investigations for Unexpected Aminophenazone Cocrystal Formation under Thiourea Reaction Conditions via Possible Enamine Assisted Rearrangement." Crystals 12, no. 5 (2022): 608. http://dx.doi.org/10.3390/cryst12050608.

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Considering the astounding biomedicine properties of pharmaceutically active drug, 4-aminophenazone, also known as 4-aminoantipyrine, the work reported in this manuscript details the formation of novel cocrystals of rearranged 4-aminophenazone and 4-nitro-N-(4-nitrobenzoyl) benzamide in 1:1 stoichiometry under employed conditions for thiourea synthesis by exploiting the use of its active amino component. However, detailed analysis via various characterization techniques such as FT-IR, nuclear magnetic resonance spectroscopy and single crystal XRD, for this unforeseen, but useful cocrystalline

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4

Karon, Brad S., Thomas M. Daly, and Mitchell G. Scott. "Mechanisms of dopamine and dobutamine interference in biochemical tests that use peroxide and peroxidase to generate chromophore." Clinical Chemistry 44, no. 1 (1998): 155–60. http://dx.doi.org/10.1093/clinchem/44.1.155.

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Abstract Dopamine and dobutamine have recently been shown to produce a negative interference in several biochemical tests that use peroxide and peroxidase to generate a chromophore. To define the chemical mechanism of this interference, we examined the effects of dopamine and dobutamine in various peroxidase-based biochemical tests. Dopamine interfered stoichiometrically with peroxidase-based tests that use 4-aminophenazone to form chromophore but interfered little in those that use other compounds to generate chromophore. Dopamine reacts with 4-aminophenazone in the presence of peroxide and p

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5

Moustafa, Ahmed H., and Hosam A. Saad. "Synthesis of Phenazone Derivatives." Journal of Chemical Research 2005, no. 5 (2005): 328–31. http://dx.doi.org/10.3184/0308234054324002.

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Some new phenazone (antipyrin) derivatives 2–11 have been synthesised by acylation, alkylation, condensation and ring closure reactions of 4-aminophenazone 1. The structures of the products have been secured by elemental analyses and spectral data (IR, 1H, and 13C NMR).

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6

Althomali, Raed H., Khalid A. Alamry, Mahmoud A. Hussein, and R. M. Guedes. "An investigation on the adsorption and removal performance of a carboxymethylcellulose-based 4-aminophenazone@MWCNT nanocomposite against crystal violet and brilliant green dyes." RSC Advances 13, no. 7 (2023): 4303–13. http://dx.doi.org/10.1039/d2ra07321h.

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The adsorption and removal performance of CMC-based 4-aminophenazone and doped MWCNTs NC was investigated CV and BG dyes. The results demonstrate the excellent potential of A-PH-CMC/MWCNTs nanocomposites as a material for CV and BG dye removal.

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7

Aromdee, Chantana, та Kamphol Raksrivong. "Spectrophotometric Determination of Piroxicam in Capsules with 4-Aminophenazone(การหาปริมาณไพรอกชีแคม ด้วย 4 - อมิโนฟีนาโชน โดยวิธีสเปกโทรโปโต..." Thai Journal of Pharmaceutical Sciences 13, № 3 (1988): 301–7. http://dx.doi.org/10.56808/3027-7922.1384.

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8

Paredes Cuaran, Angela Maria, Cindy Vanessa Castellanos Bernal, Isabella Peñaranda Lopera, Victor Manuel Prado Hernandez, and Jimmy Morales. "(Digital Presentation) A Facile Molasse-Assisted Synthesis of LaFeO₃ Lanthanum Iron Oxide Nanoparticles for Simultaneous Electrochemical Determination of Acetaminophen and 4-Aminophenazone." ECS Meeting Abstracts MA2024-02, no. 66 (2024): 4932. https://doi.org/10.1149/ma2024-02664932mtgabs.

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Using a screen-printed carbon electrode modified with lanthanum iron oxide nanoparticles as a sensing device, the heterocyclic chemicals, acetaminophen and 4-aminophenazone, which are developing pollutants, were electrochemically destroyed in PBS buffer media at pH 5.5 in this study. X-ray diffraction was used to analyze lanthanum iron oxide nanoparticles LFO NPs, which were manufactured utilizing a low-cost and straightforward approach. The simultaneous determination of acetaminophen (AC) and 4-aminophenazone (4-AM) has been accomplished through the development and validation of a novel, sens

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9

Alwehaid, AbdulAziz M. "Flow injection spectrophotometric determination of 4-aminophenazone based on diazotisation and coupling reactions." Analyst 115, no. 11 (1990): 1419. http://dx.doi.org/10.1039/an9901501419.

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10

Journal, Baghdad Science. "Transition Metal Complexes with Tridentate Ligand: Preparation, Spectroscopic Characterization, Thermal Analysis and Structural Studies." Baghdad Science Journal 13, no. 4 (2016): 770–81. http://dx.doi.org/10.21123/bsj.13.4.770-781.

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New series of metal ions complexes have been prepared from the new ligand 1,5- Dimethyl-4- (5-oxohexan-2- ylideneamino) -2-phenyl- 1H-pyrazol-3 (2H)-one derived from 2,5-hexandione and 4-aminophenazone. Then, its V(IV), Ni(II), Cu(II), Pd(II), Re(V) and Pt(IV) complexes prepared. The compounds have been characterized by FT-IR, UV-Vis, mass and 1H and 13C-NMR spectra, TGA curve, magnetic moment, elemental microanalyses (C.H.N.O.), chloride containing, Atomic absorption and molar conductance. Hyper Chem-8 program has been used to predict structural geometries of compounds in gas phase, the heat

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11

Gowda, Jayant I., and Sharanappa T. Nandibewoor. "Simultaneous electrochemical determination of 4-aminophenazone and caffeine at electrochemically pre-treated graphite pencil electrode." Analytical Methods 6, no. 14 (2014): 5147. http://dx.doi.org/10.1039/c4ay00467a.

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12

Nissa, Choirun, Syafira Noor Pratiwi, Siti Majidah, et al. "THE EFFECTS OF PAPAYA LEAVES JELLY IN LIPID PROFILE AMONG OVERWEIGHT WOMEN." Journal of Nutrition College 9, no. 4 (2020): 290–95. http://dx.doi.org/10.14710/jnc.v9i4.29160.

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Background : Insulin resistance that occurred in diabetic state could promote endothelial dysfunction which lead to metabolic disease in obese subjects. Although several studies showed papaya leaves had antidiabetic and antihyperlipidemic agent, the effect of papaya leaves jelly is rarely studied on lipid profiles among overweight women.Objectives : We aimed to examine the effect of papaya leaves jelly on lipid profiles in women with overweight. Methods : This study was a pre-posttest controlled group design with both of the groups were overweight. The treatment group consumed papayq leaves je

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13

Gowda, Jayant I., and Sharanappa T. Nandibewoor. "Electrochemical Behavior of 4-Aminophenazone Drug at a Graphite Pencil Electrode and Its Application in Real Samples." Industrial & Engineering Chemistry Research 51, no. 49 (2012): 15936–41. http://dx.doi.org/10.1021/ie302501f.

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14

Morris, H. C., P. D. Overton, J. R. Ramsay, et al. "Development and validation of an automated, enzyme-mediated colorimetric assay of salicylate in serum." Clinical Chemistry 36, no. 1 (1990): 131–35. http://dx.doi.org/10.1093/clinchem/36.1.131.

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Abstract This salicylate-specific assay can be adapted for use with most discrete analyzers, for rapid emergency or routine testing with small serum or plasma sample volumes and a single calibration. The basis of this method is as follows: salicylate monooxygenase (EC 1.14.13.1) converts salicylate to catechol in the presence of NADH; the catechol then reacts with 4-aminophenazone under alkaline conditions, catalyzed by manganese ions, to produce a red dye. Incorporation of an NADH-regenerating system, involving glucose and glucose dehydrogenase, into the enzyme reagent ensures that the workin

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15

Pardeep, Kaur, Sharma Sunita, Gaba Jyoti, and Rashmi. "Conventional vs microwave assisted synthesis of different substituted heterocyclic amides." Journal of Indian Chemical Society Vol. 96, Mar 2019 (2019): 401–5. https://doi.org/10.5281/zenodo.5651034.

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Department of Chemistry, Department of Plant Breeding and Genetics, Punjab Agricultural University, Ludhiana-141 004, Punjab, India <em>E-mail: </em>pardip2493@gmail.com, sunita_sharma@pau.edu, jyotgcw@gmail.com, rashmibakshi280@gmail.com <em>Manuscript received online 05 September 2018, revised 20 February 2019, accepted 26 February 2019</em> Amides have great importance in the field of synthetic organic chemistry because of their presence in many biologically active molecules. Condensation of different carboxylic acids with different amines is one of the most convenient method for amide synt

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16

Murtaza, Shahzad, Muhammad Shoaib Akhtar, Farina Kanwal, Aadil Abbas, Shoaib Ashiq, and Saima Shamim. "Synthesis and biological evaluation of schiff bases of 4-aminophenazone as an anti-inflammatory, analgesic and antipyretic agent." Journal of Saudi Chemical Society 21 (January 2017): S359—S372. http://dx.doi.org/10.1016/j.jscs.2014.04.003.

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17

Arshad, Nasima, Mukhtar Ahmad, Muhammad Zaman Ashraf, and Humaira Nadeem. "Spectroscopic, electrochemical DNA binding and in vivo anti-inflammatory studies on newly synthesized Schiff bases of 4-aminophenazone." Journal of Photochemistry and Photobiology B: Biology 138 (September 2014): 331–46. http://dx.doi.org/10.1016/j.jphotobiol.2014.06.014.

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18

Lespinas, F., G. Dupuy, F. Revol, and C. Aubry. "Enzymic urea assay: a new colorimetric method based on hydrogen peroxide measurement." Clinical Chemistry 35, no. 4 (1989): 654–58. http://dx.doi.org/10.1093/clinchem/35.4.654.

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Abstract We describe a new enzymic colorimetric method in which urea is measured in serum by use of a single reagent mixture. Ammonia produced by urea hydrolysis, catalyzed by urease, reacts with glutamate and ATP in the presence of glutamine synthetase. The ADP so produced is assayed in reactions catalyzed sequentially by pyruvate kinase and pyruvate oxidase in a system that generates hydrogen peroxide. The hydrogen peroxide is measured at 500 or 550 nm in a reaction catalyzed by horseradish peroxidase, with phenol/4-aminophenazone as the chromogen. The reaction is complete in 15 min at 37 de

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19

Journal, Baghdad Science. "Synthesis , characterization and biological activity study of N-substituted sulfonamido maleimides substituted with different heterocycles." Baghdad Science Journal 7, no. 1 (2010): 641–53. http://dx.doi.org/10.21123/bsj.7.1.641-653.

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Eighteen new cyclic imides (maleimides) conncted to benzothiazole moiety through sulfonamide group were synthesized via multistep synthesis.The first step involved preparation of two maleamic acids N-phenylmaleamic acid and N-benzylmaleamic acid via reaction of maleic anhydride with aniline or benzyl amine.Dehydration of the prepared amic acids by treatment with acetic anhydride and anhydrous sodium acetate in the second step afforded N-phenylmaleimide and N- benzyl maleimide which in turn were treated with chlorosulfonic acid in the third step to afford 4-(N-maleimidyl) phenyl sulfonyl chlori

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20

Bolhuis, P. A., R. Zwart, P. R. Bär, M. de Visser, and H. J. van der Helm. "Rapid determination of the hypoxanthine increase in ischemic exercise tests." Clinical Chemistry 34, no. 8 (1988): 1607–10. http://dx.doi.org/10.1093/clinchem/34.8.1607.

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Abstract After ischemic exercise tests, performed to detect glycogenoses or myoadenylate deaminase (EC 3.5.4.6) deficiency, the increases in serum lactate and ammonia usually are measured. Determination of hypoxanthine instead of ammonia can also be used to show myoadenylate deaminase deficiency, but HPLC of hypoxanthine is time-consuming. As a substitute, we developed an indirect enzymatic equilibrium method for hypoxanthine based on coupling the chromogenic system 3,5-dichloro-2-hydroxy-benzenesulfonic acid/4-aminophenazone with formation of hydrogen peroxide by xanthine oxidase (EC 1.1.3.22

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21

Saini, Harpal S., and Neil Wratten. "Quantitative Determination of Total Glucosinolates in Rapeseed and Meal Digests." Journal of AOAC INTERNATIONAL 70, no. 1 (1987): 141–45. http://dx.doi.org/10.1093/jaoac/70.1.141.

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Abstract A method has been developed for the quantitative determination of total glucosinolates in enzymic digests of seeds and meals of rapeseed cultivars. The method is based on the determination of the glucose released after myrosinase digestion and subsequent deproteinization, using the glucose oxidase-peroxidase system with 4-aminophenazone as the oxygen acceptor. The myrosinase was prepared from white mustard seeds and partially purified to remove other glucose-liberating enzyme activities. Endogenous enzyme activities in the samples analyzed were also removed by heat treatment before an

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22

Anoopjit, Singh Kooner, Sharma S., and Sharma Poonam. "Synthesis and microbial activity of acrylamides with heteroatoms." Journal of Indian Chemical Society Vol. 91, Feb 2014 (2014): 293–98. https://doi.org/10.5281/zenodo.5749142.

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Department of Chemistry, Punjab Agricultural University, Ludhiana-141 004, Punjab, India <em>E-mail </em>: ajsingh@live.in Department of Plant Breeding and Genetics, Punjab Agricultural University, Ludhiana-141 004, Punjab, India E-mail : sonita_311@rediffmail.com; poonam_sharma@pau.edu <em>Manuscript received 05 September 2012, revised 11 March 2013, accepted 18 April 2013</em> The modified condensation reaction of benzaldehyde (1a), 2-chlorobenzaldehyde (1c), 3-nitrobenzaldehyde (1b) and 4-chlorobenzaldehyde (1d) with <strong>α</strong>-proton containing acids viz. acetic acid (2a) and

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23

Ganiyu, Soliu O., Nihal Oturan, Clément Trellu, et al. "Electrochemical Abatement of Analgesic Antipyretic 4‐Aminophenazone using Conductive Boron‐Doped Diamond and Sub‐Stoichiometric Titanium Oxide Anodes: Kinetics, Mineralization and Toxicity Assessment." ChemElectroChem 6, no. 6 (2019): 1808–17. http://dx.doi.org/10.1002/celc.201801741.

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24

Susilowati, Retno, and Abdul Malik Setiawan. "Cinnamomum burmannii (Nees & T. Nees) Blume and Eleutherine palmifolia (L.) Merr. extract combination ameliorate lipid profile and heart oxidative stress in hyperlipidemic mice." July-2020 13, no. 7 (2020): 1404–9. http://dx.doi.org/10.14202/vetworld.2020.1404-1409.

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Background and Aim: Hyperlipidemia is an important risk factor for cardiovascular disease. The use of statins has adverse side effects that result in oxidative stress disorders. The objective of this study was to investigate the antihyperlipidemic effect of a combination of Cinnamomum burmannii and Eleutherine palmifolia extract in high-fat diet (HFD)-induced hyperlipidemia mice. Materials and Methods: Mice were divided into eight groups (n=4): Control group or healthy mice (normal), HFD-induced hyperlipidemic mice without any treatment (CE0), HFD-induced hyperlipidemic mice treated with 3.6 m

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25

Susilowati, Retno, and Abdul Malik Setiawan. "Cinnamomum burmannii (Nees & T. Nees) Blume and Eleutherine palmifolia (L.) Merr. extract combination ameliorate lipid profile and heart oxidative stress in hyperlipidemic mice." July-2020 13, no. 7 (2020): 1404–9. http://dx.doi.org/10.14202/10.14202/vetworld.2020.1404-1409.

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Background and Aim: Hyperlipidemia is an important risk factor for cardiovascular disease. The use of statins has adverse side effects that result in oxidative stress disorders. The objective of this study was to investigate the antihyperlipidemic effect of a combination of Cinnamomum burmannii and Eleutherine palmifolia extract in high-fat diet (HFD)-induced hyperlipidemia mice. Materials and Methods: Mice were divided into eight groups (n=4): Control group or healthy mice (normal), HFD-induced hyperlipidemic mice without any treatment (CE0), HFD-induced hyperlipidemic mice treated with 3.6 m

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26

Nurmasitoh, Titis, and Miranti Dewi Pramaningtyas. "Honey improves lipid profile of diet-induced hypercholesterolemic rats." Universa Medicina 34, no. 3 (2016): 177. http://dx.doi.org/10.18051/univmed.2015.v34.177-186.

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Background<br />Coronary heart disease (CHD) is a major cause of morbidity and mortality throughout the world, including Indonesia. One of the risk factors for CHD is hypercholesterolemia. One of the natural products that has been developed for the treatment of hypercholesterolemia is honey. Honey contains fructooligosaccharides, various vitamins, minerals, and enzymes which are supposedly able to lower blood cholesterol levels. This research aimed to study the influence of honey on the levels of blood total cholesterol, triglyceride, and low density lipoprotein (LDL) levels in Wistar ra

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27

Rashmi, Arora, Sharma Rishi, Tageza Abhishek, et al. "Design and synthesis of novel 4-aminophenazone Schiff bases by grinding technique as prospective anti-inflammatory agents." Journal of Applied Pharmaceutical Science, March 5, 2021. http://dx.doi.org/10.7324/japs.2021.11s105.

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28

María-José, Castro-Castro, Cachón-Suárez Isabel, Maestre-Fernández Andrea, and Navarro-Badal Rosa. "Interference of metamizole in the measurement of serum creatinine concentration." Advances in Laboratory Medicine / Avances en Medicina de Laboratorio, April 26, 2024. http://dx.doi.org/10.1515/almed-2023-0163.

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Abstract Objectives There is little literature on the interference of metamizole in measurement creatinine concentration by the enzymatic method. Some studies have postulated that the dipyrone molecule is responsible for interfering in the last reaction of the enzymatic method sequence, due to its similarity with the 4-aminophenazone molecule. The aim of this study is to examine the interference of the presence of metamizole in the measurement of serum creatinine concentration by the enzymatic method. Methods An interference study of the measurement of creatinine concentration was carried out

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29

"MC-15 The assay of serum urate on the American monitor perspective analyser using the 3,5-dichloro-2-hydroxybenzene sulphonate/4-aminophenazone chromogenic system." Clinical Biochemistry 21, no. 6 (1988): 383. http://dx.doi.org/10.1016/s0009-9120(88)80035-3.

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30

Tahir, Muhammad Nawaz, Zahid Rashid, Khurram Shahzad Munawar, et al. "Synthesis, Characterization, and Exploration of Supramolecular Assembly in a 4-Aminophenazone Derivative: A Comprehensive Study Including Hirshfeld Surface Analysis, Computational Investigation, and Molecular Docking." Journal of Molecular Structure, March 2024, 137953. http://dx.doi.org/10.1016/j.molstruc.2024.137953.

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31

"Relationship between Insulin Sensitivity and Body Fat Composition, and Leptin Sensitivity in Non-Obese and Overweight/Obese Adults." Myanmar Health Sciences Research Journal 31, no. 3 (2019): 212–18. http://dx.doi.org/10.34299/mhsrj.00950.

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Both insulin and leptin are major contributors for the body energy balance. Obesity is a state of energy imbalance and is also associated with changes in both insulin sensitivity and leptin sensitivity. The aim of this study was to find out the relationship between insulin sensitivity and body fat composition, and leptin sensitivity in non-obese and obese adults. A total of 86 adults participated: 42 non-obese and 44 over-weight/obese. Body fat (BF) percent was determined by skinfold method. Fasting plasma glucose was analyzed by glucose oxidase-phenol and 4 aminophenazone (GOD-PAP) method usi

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32

"5116730 Amino acid substituted 4-aminophenazones for measuring enzyme activity." Biotechnology Advances 10, no. 3 (1992): 485. http://dx.doi.org/10.1016/0734-9750(92)90477-q.

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