Relevant bibliographies by topics / 4-Thiadiazoles[3

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Academic literature on the topic '4-Thiadiazoles[3'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "4-Thiadiazoles[3"

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Zakaria, Medhat Mahamed. "Important of Azoles." American International Journal of Biology and Life Sciences 1, no. 1 (2019): 6–14. http://dx.doi.org/10.46545/aijbls.v1i1.30.

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Azoles are one of a cyclic derivatives of chemical heterocyclic chemical and organic compounds including g a five member di unsaturated ring structure composed of bi nitrogen atoms at position (3 and 4) and one sulfur atom at position (1).
 
 
 
 
 
 
 
 
 
 
 
 Most of prepared work on the four thiadiazoles has been on the 1, 3, 4-thiadiazoles. Physical, theoretical, and spectroscopic properties have been reviewed .
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2

Kong, Yung Cheol, and Kyongtae Kim. "Exploratory chemistry of 3-aroylformamido-4-aryl-1,2,5-thiadiazoles." Journal of Heterocyclic Chemistry 36, no. 2 (1999): 515–23. http://dx.doi.org/10.1002/jhet.5570360231.

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3

Cowden, WB, SJ Sullivan, and DJ Brown. "Unfused Heterobicycles as Amplifiers of Phleomycin. VII> Some Bithiazoles; Thienyl-, Furanyl- and Thiazolyl-thiadiazoles and Related Oxadiazoles." Australian Journal of Chemistry 38, no. 8 (1985): 1257. http://dx.doi.org/10.1071/ch9851257.

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Syntheses are described for several unfused heterobicycles including 4,5′- and 2,4′-bithiazoles, 5-(thiazol-4′ and 5′-yl)-1,3,4- thiadiazoles , 5-(thien-2′-yl)-, 5-(furan-2′ and 3′-yl)-, thiadiazoles and related oxadiazoles, all with side chains containing dialkylamine terminal groups. The activities of these compounds as amplifiers of phleomycin -G are reported.
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4

Abu-Hashem, Ameen Ali, and Rasha A. M. Faty. "Synthesis, Antimicrobial Evaluation of Some New 1, 3, 4-Thiadiazoles and 1, 3, 4- Thiadiazines." Current Organic Synthesis 15, no. 8 (2018): 1161–70. http://dx.doi.org/10.2174/1570179415666180720114547.

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Background: 1, 3, 4-thiadiazoles, 1, 3, 4-thiadiazines and thienopyrimidines have newly attracted attention due to their forceful pharmacological activities. They showed antimicrobial, antiviral, analgesic and anti-inflammatory properties. Objective: The aim of this research is to synthesize new thiadiazolothienopyrimidines (2-10), thienopyrimidothiadiazines (11-15), quinoxaline-thienopyrimidinones (16) and thienopyrimido- thiadiazinoquinoxalinones (17) via effectual high yield procedure for assessing their antimicrobial activity. Method: A series of new 1, 3, 4-thiadiazolothienopyrimidines, t
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5

Ergena, Asrat, Yerra Rajeshwar, and Gebremedhin Solomon. "Synthesis and Diuretic Activity of Substituted 1,3,4-Thiadiazoles." Scientifica 2022 (April 8, 2022): 1–9. http://dx.doi.org/10.1155/2022/3011531.

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1,3,4-Thiadiazole nuclease, a 5-membered heterocyclic ring system containing two nitrogen and one sulfur atoms in addition to carbon atoms, is compound that showed promising results in the process of searching new diuretic agents. In this study, seven 5- and 2-thioate derivatives of 1, 3, 4-thiadiazoles were synthesized by substitution reaction using acetone as solvent and K2CO3 as a base. The compounds ware then characterized by using IR and NMR spectroscopy. The diuretic activity of the compounds was evaluated on Swiss albino mice by measuring urine volume, urinary pH, and urinary Na+, K+, a
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6

Мирко, І. І., Ю. І. Горак, Т. І. Чабан, І. В. Драпак, and В. С. Матійчук. "Synthesis and antitumor properties of some new 3-R-6-(5-arylfuran-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles." Farmatsevtychnyi zhurnal, no. 5 (October 22, 2021): 37–49. http://dx.doi.org/10.32352/0367-3057.5.21.04.

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One of the promising methods of creating antitumor drugs is the screening of potential antitumor agents among synthesized compounds. Nitrogen-based heterocycle analogues are an extremely important class of organic substances that are widely used in medical chemistry. [1,2,4]Triazolo[3,4-b][1,3,4] thiadiazoles are among the little-studied and hard-to-reach members of this class of compounds.
 The aim of our work was to synthesize some new 3-R-6-(5-arylfuran-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles, as well as the study of their antitumor activity.
 The objects of study were 3-R-
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7

JAG, MOHAN, S. R. ANJANBYULU G., and KIRAN. "Heterocyclic Systems containing Bridgehead Nitrogen Atom. Synthesis of Thiadiazolo[2',3', : 2,1 )imidazo[ 4,5-b)quinoxaline, Jmidazo[2,1-b ]-1,3,4-thiadiazoles and their Brominated Products." Journal of Indian Chemical Society Vol. 66, Feb 1989 (1989): 118–19. https://doi.org/10.5281/zenodo.6303535.

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Department of Chemistry, Maharshi Dayanand University, Rohtak-124&nbsp;001 <em>Manuscript received 25 March 1988, accepted 2 November 1988</em> 2-Amino-5-alkylthiadiazoles (1) condense with \(\propto\)-haloketones and 2,3-dichloroquinoxalene to furnish&nbsp;respectively the cyclised products, 2,6-disubstituted imidazo [2,1-b]-1,3,4-thiadiazoles (2) and 2-substituted-thiadiazolo(2<em>&#39;,</em>3<em>&#39;</em>: 2,1] imidazo[4,5-b]- quinoxaline (4). Bromination of 2 furnishes 5-bromo-2,6-disubstituted-imidazo[2,1-b]- thiadiazoles (3). The antimicrobial activities of some of the compounds have be
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8

Joshi, K. A., J. M. Dhalani, H. B. Bhatt, and K. M. Kapadiya. "Synthesis of some new 6-aryl-3-(4-isopropylphenyl)[1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles and its anti-microbial study." Current Chemistry Letters 10, no. 4 (2021): 479–88. http://dx.doi.org/10.5267/j.ccl.2021.4.003.

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New series of fused 1,2,4-triazoles, i.e., 3-(4-isopropylphenyl)-6-substituted phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles (5a-5j) have been synthesized via a four-step procedure and using eco-friendly reaction condition at some steps of the synthesis. It was adopted by the formation of hydrazide of methyl 4-isopropylbenzoate (1) followed by reaction with CS2 in basic media to afford potassium salt, which on cyclized to our essential step, 4-amino-5-(4-isopropylphenyl)-4H-1,2,4-triazole-3-thiol (4). The desired adducts (5a-5j) were formed by (4) on reaction with various aromatic acids in
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9

Smicius, Romualdas, Virginija Jakubkiene, Milda M. Burbuliene, Aiste Mikalainyte, and Povilas Vainilavicius. "Synthesis of 1-(6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydro-3-Pyrimidinyl)Acetyl-4-Alkyl(Aryl)Thiosemicarbazides and their Heterocyclisation to 1,2,4-Triazoles and 1,3,4-Thiadiazoles." Journal of Chemical Research 2002, no. 4 (2002): 170–72. http://dx.doi.org/10.3184/030823402103171555.

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5-(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydro-3-pyrimidinyl)methyl-1,3,4-oxadiazole-2-thione reacts with amines to give 1-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-3-pyrimidinyl)acetyl-4-alkyl(aryl)thiosemicarbazides, which on treatment with base or acid undergo cyclisation to 4-alkyl-1,2,4-triazole-2-thiones or 4-amino-1,3,4-thiadiazoles, respectively.
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10

Lelyukh, Maryan I., Ivan O. Krukovskiy, Zoryana M. Komarenska, Nataliia V. Yelahina, Taras I. Chaban, and Ihor G. Chaban. "Appliance Features of 4-Amino-1,2,4-triazole-3-thiols in the Synthesis of 3,6-Disubstituted [1,2,4]Triazolo[3,4-b] [1,3,4]thiadiazoles." Acta Chimica Slovenica 72, no. 2 (2025): 238–59. https://doi.org/10.17344/acsi.2025.9169.

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4-Amino-5-substituted-4H-1,2,4-triazole-3-thiols are versatile synthons for the construction of various biologically active heterocycles. This is provided by the close proximity of the amino and mercapto groups, which serve as readily accessible nucleophilic centers for the preparation of N-bridged heterosystems. One of the possible and convenient directions of using 4-amino-4H-1,2,4-triazole-3-thiols in heterocyclic synthesis is based on their utilization in reaction with various carboxylic acids in the presence of dehydrating reagents, most often phosphorus oxychloride. Synthesized as follow
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Dissertations / Theses on the topic "4-Thiadiazoles[3"

1

Seltmann, Jens. "Struktur-Eigenschaftsbeziehungen V-förmiger Mesogene zur Realisierung biaxial nematischer Mesophasen." Doctoral thesis, Universitätsbibliothek Chemnitz, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-67693.

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Die vorliegende Arbeit befasst sich mit der Synthese und der Untersuchung von Struktur-Eigenschaftsbeziehungen neuartiger V-förmiger, formstabiler Mesogene zur Realisierung biaxial nematischer Mesophasen (Nb). Alle synthetisierten Verbindungen besitzen ein formtreues Oligo(phenylenethinylen)-Grundgerüst, an welches laterale Alkyloxyketten und verschiedene terminale Substituenten (z. B. -CN, O(CH2)nCOOEt, Pyridyle) angebunden wurden. Durch dieses spezielle Design erhält man ausschließlich nematische und keine höher geordneten flüssigkristallinen Phasen. Durch den Einsatz verschiedener zentraler
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Journal articles
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