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Journal articles on the topic '973.3/092 b'

Author: Grafiati

Published: 28 July 2024

Last updated: 31 July 2025

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1

Vertullo, Christopher J., Marina Piepenbrink, Patrick A. Smith, Adrian J. Wilson, and Coen A. Wijdicks. "Biomechanical Testing of Three Alternative Quadrupled Tendon Graft Constructs With Adjustable Loop Suspensory Fixation for Anterior Cruciate Ligament Reconstruction Compared With Four-Strand Grafts Fixed With Screws and Femoral Fixed Loop Devices." American Journal of Sports Medicine 47, no. 4 (2019): 828–36. http://dx.doi.org/10.1177/0363546518825256.

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Background: Quadrupled semitendinosus (ST) grafts for anterior cruciate ligament (ACL) reconstruction have advantages of greater graft diameter and gracilis (G) preservation compared with doubled ST-G grafts. However, a paucity of biomechanical data are available regarding different preparation techniques for these constructs. Purpose: To biomechanically analyze 3 alternative tendon constructs fixed with adjustable suspensory fixation devices on the femur and tibia compared with a matched 4-strand construct fixed with a tibial screw and femoral fixed loop device. Study Design: Controlled labor

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Kepert, Cameron J., Lu Wei-Min, Peter C. Junk, Brian W. Skelton, and Allan H. White. "Structural Systematics of Rare Earth Complexes. XI (‘Maximally’) Hydrated Rare Earth(III) Trifluoro- and Trichloro-acetates." Australian Journal of Chemistry 52, no. 6 (1999): 459. http://dx.doi.org/10.1071/ch98042.

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Room-temperature single-crystal X-ray structure determinations carried out on ‘maximally’ hydrated rare earth(III) trifluoroacetates, Ln(tfa)3.x H2O, crystallized at room temperature, show the Ln = La, Ce adducts to be isomorphous and monoclinic, P 21/c, a ≈ 11·9, b ≈ 12·8, c ≈ 9·8 8 Å, β ≈ 103·7°, Z = 4; they are trihydrates. The Ln = Pr, Lu (and, implicitly, intermediate Ln) adducts are also monoclinic, P 21/c, Z = 4, and trihydrates, but of a different polymorph, with a ≈ 9·2, b 18·8, c ≈ 9·8 Å, β ≈ 114°. For the four determinations, conventional R values on |F| were 0·038, 0·032, 0·036, an

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Pollard, Jessica, Todd A. Alonzo, Robert B. Gerbing, et al. "Negative Prognostic Impact Of High CD33 Expression Is Negated With The Use Of Gemtuzumab Ozogamicin: A Report From The Children’s Oncology Group." Blood 122, no. 21 (2013): 491. http://dx.doi.org/10.1182/blood.v122.21.491.491.

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Abstract CD33 is expressed on leukemic blasts of most patients with acute myeloid leukemia (AML) and is the target for gemtuzumab ozogamicin (GO), a toxin-conjugated anti-CD33 monoclonal antibody. CD33 expression of leukemic blasts was prospectively quantified within the context of COG AAML0531, a phase III randomized study for de novo AML in which patients were randomized to receive conventional chemotherapy (Arm A) vs. GO + conventional chemotherapy (Arm B) to determine the impact of CD33 expression on outcome within the context of this GO randomization. CD33 mean fluorescent intensity (MFI)

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Overbeck, Tobias Raphael, Annika Reiffert, Katja Schmitz, et al. "NTRK Gene Fusions in Non-Small-Cell Lung Cancer: Real-World Screening Data of 1068 Unselected Patients." Cancers 15, no. 11 (2023): 2966. http://dx.doi.org/10.3390/cancers15112966.

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(1) Background: The main objectives of our study are (i) to determine the prevalence of NTRK (neurotrophic tyrosine kinase) fusions in a routine diagnostic setting in NSCLC (non-small cell lung cancer) and (ii) to investigate the feasibility of screening approaches including immunohistochemistry (IHC) as a first-line test accompanied by fluorescence in situ hybridization (FISH) and RNA-(ribonucleic acid-)based next-generation sequencing (RNA-NGS). (2) Methods: A total of 1068 unselected consecutive patients with NSCLC were screened in two scenarios, either with initial IHC followed by RNA-NGS

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Frahm, Eckart. "Michael Streck, Altorientalistik. Einführung, Baden-Baden (Nomos) 2023, 290 S., ISBN 973-3-8487-8197-3 (brosch.), € 29,–." Klio 107, no. 1 (2025): 268–72. https://doi.org/10.1515/klio-2025-2001.

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Kosaka, Hisashi, Yasuyuki Kaneno, and Takayuki Takasugi. "Ductilization of a Ni₃(Si,Ti) Intermetallic Alloy by Addition of Interstitial Type Elements." Advanced Materials Research 409 (November 2011): 321–26. http://dx.doi.org/10.4028/www.scientific.net/amr.409.321.

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The effect of a concomitant doping of interstitial type elements boron (B) and carbon (C), and boron (B) and nitrogen (N) on tensile properties of a Ni3(Si,Ti) intermetallic alloy was investigated in the temperature range between room temperature and 973 K. It was found that the concomitant doping of (C/B) and (N/B) remarkably improved the intermediate-temperature tensile elongation of the Ni3(Si,Ti) alloy compared with the simple doping of B or C. It was also shown that the fracture surface of the alloy doped with (C/B) and (N/B) exhibited the ductile transgranular fracture mode while that of

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7

FU, CHIH-CHIANG, JASON SHIAN-CHING JANG, I.-SUI LEE, and HUEI-SEN WANG. "STRAIN RATE DEPENDENCE ON THE HIGH TEMPERATURE MECHANICAL BEHAVIOR OF THE NI-18SI-3.0NB-1.0CR-0.2B INTERMETALLIC ALLOY." International Journal of Modern Physics B 23, no. 06n07 (2009): 1040–46. http://dx.doi.org/10.1142/s0217979209060439.

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The effect of strain rate and temperature on the mechanical behavior of the Ni -18 Si -3.0 Nb -1.0 Cr -0.2 B alloy was investigated by atmosphere-controlled tensile testing in vacuum and air atmosphere at different strain rates and different temperatures. The results reveal that the Ni -18 Si -3.0 Nb -1.0 Cr -0.2 B alloy exhibits ductile mechanical behavior (UTS > 1200 MPa, ε > 8%) at room temperature under different atmosphere conditions. In addition, both of the ultimate tensile strength and elongation exhibit quite insensitive response with respect to the loading strain rate when test

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Ullah, Ihsan, Muhammad Israr, Jehanzeb Khan, and Mushtaq Khatak. "To compare the efficacy of timolol maleate 0.5% vs fixed combination of timolol maleate 0.5%, and brimonidine tartrate 0.2% in control of raised intra ocular pressure in patients undergone Nd-Yag laser capsulotomy." American Journal of Health, Medicine and Nursing Practice 7, no. 4 (2022): 1–6. http://dx.doi.org/10.47672/ajhmn.933.

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Purpose: The purpose of the study is to compare the efficacy of Timolol maleate alone vs fixed combination of Timolol maleate 0.5% with Brimonidine 0.2% in patients undergone Nd-Yag laser capsulotomy. Methodology: 100 patients with posterior capsular opacification were enrolled though OPD. They were placed in 2 groups with 50 patients each. Group A received Timolol maleate 0.5% alone while group B received combination of timolol maleate with Brimonidine tartrate. Results: In group A 3 patients developed acute raise of intraocular pressure despite of Timolol maleate use while goup B

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Eberhardt, Jan, Melissa J. Hobson, Thomas Henning, et al. "Three Warm Jupiters around Solar-analog Stars Detected with TESS*." Astronomical Journal 166, no. 6 (2023): 271. http://dx.doi.org/10.3847/1538-3881/ad06bc.

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Abstract We report the discovery and characterization of three giant exoplanets orbiting solar-analog stars, detected by the TESS space mission and confirmed through ground-based photometry and radial velocity measurements taken at La Silla observatory with FEROS. TOI-2373 b is a warm Jupiter orbiting its host star every ∼13.3 days, and is one of the most massive known exoplanet with a precisely determined mass and radius around a star similar to the Sun, with an estimated mass of m p = 9.3 − 0.2 + 0.2 M jup and a radius of r p = 0.93 − 0.2 + 0.2 R jup . With a mean density of ρ = 14.4 − 1.0 +

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Bình, Nguyễn Thanh, та Nguyễn Thùy Trang. "Đặc điểm kiểu gen HLA các mẫu máu cuống rốn lưu trữ tại Bệnh viện Nhi Trung ương". Tạp chí Nghiên cứu Y học 143, № 7 (2021): 8–14. http://dx.doi.org/10.52852/tcncyh.v143i7.367.

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HLA là gen nằm trên cánh ngắn nhiễm sắc thể số 6 ở người gồm nhiều locus và thường di truyền theo cụm. Việc định typ HLA cần thiết trong việc lựa chọn cặp ghép phù hợp đặc biệt trong ghép tế bào gốc tạo máu. Nghiên cứu cắt ngang xác định tỷ lệ các allele HLA-A, HLA-B, HLA-DRB1 và haplotype của các lucus gen này trên 233 mẫu máu cuống rốn được lưu trữ tại Ngân hàng tế bào gốc Bệnh viện Nhi Trung ương từ năm 2011-2014. Các mẫu máu cuống rốn được làm xét nghiệm định typ HLA cho 3 locus HLA-A; HLA-B; HLA-DRB1 bằng kỹ thuật PCR-SSP sử dụng bộ KIT AllSetTM Gold SSP. Kết quả cho thấy Locus HLA-A có 1

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Dauvilliers, Yves, Abby Chen, Marisa Whalen, Wayne Macfadden, and Michael Thorpy. "0592 Efficacy of Lower-Sodium Oxybate by Baseline Sleep Inertia in a Phase 3 Clinical Study in Patients With Idiopathic Hypersomnia." SLEEP 46, Supplement_1 (2023): A260. http://dx.doi.org/10.1093/sleep/zsad077.0592.

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Abstract Introduction Idiopathic hypersomnia is a debilitating neurologic sleep disorder. Sleep inertia (difficulty awakening) is a common symptom that can significantly impair functioning and quality of life. This post hoc analysis evaluated response to lower-sodium oxybate (LXB; Xywav®) by baseline sleep inertia in a phase 3 trial (NCT03533114). Methods Eligible participants began LXB treatment with an open-label treatment titration and optimization period (10–14 weeks), followed by a 2-week stable-dose period (SDP). Participants were randomized to placebo or continued LXB treatment during a

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Dens, Nathalie, Patrick De Pelsmacker, and Nathalia Purnawirawan. "“We(b)care”." Journal of Service Management 26, no. 3 (2015): 486–515. http://dx.doi.org/10.1108/josm-03-2014-0082.

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Purpose – Consumers often discuss brands and companies online, but no research details how service providers’ responses to online reviews influence other readers’ perceptions of the reviews and responses. Based on justice theory and the accountability principle, both integrated in equity theory, the purpose of this paper is to examine how service providers should react to different degrees of negative reviews to enhance readers’ attitudes, patronage intentions, and intentions to spread positive word of mouth. Design/methodology/approach – A 3 (review set balance: positive, neutral, negative) ×

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Whittall, Ian R., Mark G. Humphrey та David C. R. Hockless. "Structural Systematics of Metal Acetylide Complexes. II. X-Ray Studies of Some Nickel σ-Acetylide Complexes". Australian Journal of Chemistry 51, № 3 (1998): 219. http://dx.doi.org/10.1071/c97082.

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The structures of Ni(C≡CR)(PPh3)(η-C5H5) (R = Ph (1), C6H4-4-NO2 (2), 4-C6H4C6H4-4′-NO2 (3), (E)-4-C6H4CH=CHC6H4-4′-NO2 (4), 4-C6H4C≡CC6H4-4′-NO2 (5), 4-C6H4N=CHC6H4-4′-NO2 (6)) have been determined by single-crystal X-ray diffraction studies, refining by full-matrix least-squares analysis. For (1), crystals are triclinic, space group P-1, with a 10·094(2), b13·429(3), c 18·835(5) Å,α 103·24(2), β 91·50(2), γ 90·10(2)°, Z 4, 5844 unique reflections (595 parameters), converging at R 0·033 and Rw 0·024. For (2), crystals are orthorhombic, space group Pna21, with a 16·799(2), b 8·681(2), c 17·485

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Harb, Wael, Mansoor N. Saleh, Kyriakos P. Papadopoulos, et al. "Clinical Trial Results from the Subgroup of Lymphoma/CLL in a Phase 1 Study of ARQ 092, a Novel Pan AKT-Inhibitor." Blood 126, no. 23 (2015): 5116. http://dx.doi.org/10.1182/blood.v126.23.5116.5116.

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Abstract Background: ARQ 092 is an oral allosteric, potent and selective AKT inhibitor with in vitro and in vivo activity in solid and hematological tumors. ARQ 092-101, the first clinical trial of ARQ 092, has enrolled more than 100 subjects with advanced solid tumors or recurrent malignant lymphoma. As reported previously, the dose escalation portion of the study has been completed and two dosing schedules (intermittent and weekly), are recommended for phase 2 studies. The recommended phase 2 dose (RP2D) for the intermittent dosing schedule is 200 mg once daily (QD) (one week on, one week of

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15

Jendrzejczyk, Dominika, Wojciech Gierlotka, and Krzysztof Fitzner. "Thermodynamic properties of liquid silver–indium–antimony alloys determined from e.m.f. measurements." International Journal of Materials Research 97, no. 11 (2006): 1519–25. http://dx.doi.org/10.1515/ijmr-2006-0237.

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Abstract The thermodynamic properties of liquid Ag–Sb –In alloys were determined using solid oxide galvanic cells with zirconia electrolyte. The following galvanic cells were employed: in the temperature range from 973 to 1200 K. (I) R e + kanthal, A g x − I n y − S b ( 1 − x − y ), I n 2 O 3 / / Z r O 2 + Y 2 O 3 / / N i O , N i , P t $$\begin{array}{l}\mathrm{Re}+\text { kanthal, } \mathrm{Ag}_{x}-\mathrm{In}_{y}-\mathrm{Sb}_{(1-x-y),} \\ \mathrm{In}_{2} \mathrm{O}_{3} / / \mathrm{ZrO}_{2}+\left(\mathrm{Y}_{2} \mathrm{O}_{3}\right) / / \mathrm{NiO}, \mathrm{Ni}, \mathrm{Pt}\end{array}$$ Ther

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16

Hönle, Wolfgang, Sigrid Furuseth та Hans Georg von Schnering. "Synthesis and Crystal Structure of Ordered, Orthorhombic α-NbBr5". Zeitschrift für Naturforschung B 45, № 7 (1990): 952–56. http://dx.doi.org/10.1515/znb-1990-0706.

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Niobium pentabromide, NbBr5, is prepared in the orthorhombic ordered (α)-form from the elements in sealed quartz ampoules (Nb powder, Br2, l) at 973 K. The structure has been determined from single crystal data (a = 1288.8(2), b = 1869.0(3), c = 614.9(1) pm; Pnma (No. 62); Z = 8; R = 0.055). α-NbBr5_ forms dimeric Nb2Br10 molecules with d̄(Nb–Brb) = 271.5 pm, d̄(Nb–Bre) = 240.8 pm and d̄(Nb– Bra) = 246.1 pm. α-NbBr5 is a diamagnetic semiconductor with cgsχmoldia(300 K) = –72 × 10-6 cm3/mol. The band gaps of NbCl5, α-NbBr5 and NbI5 have been determined by diffuse reflection to be Eg(NbCl5) = 2.

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McDonagh, Andrew M., Mark G. Humphrey, and David C. R. Hockless. "Preparation of cis- and trans-[OsCl2(Me2SO)4], and X-Ray Crystal Structures of the All-S-Bound Isomers." Australian Journal of Chemistry 51, no. 9 (1998): 807. http://dx.doi.org/10.1071/c98017.

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Efficient syntheses of the cis and trans isomers of [OsCl2(Me2SO)4] are reported. While a structural study of thetrans isomer confirms the spectroscopically assigned all-S-bound Me2SO configuration, a crystallographic determination of the cis isomer reveals a previously unheralded all-S-bound Me2SO geometry, in contrast to the spectroscopically inferred configuration predominant in solution which has one O-bound ligand. Fortrans-[OsCl2(Me2SO)4], crystals are tetragonal, space group I 4/m, with a 9·092(2), c 11·212(3) Å, Z 2, 566 unique reflections (34 parameters), converging at R 0·026 and Rw

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Otto, Eckart. "Faist, Betina: Assyrische Rechtsprechung im 1. Jahrtausend v. Chr. Münster: Zaphon 2020. 376 S. 80 = dubsar 15. Hartbd. € 90,00. ISBN 978-3-96327-092-5." Orientalistische Literaturzeitung 116, no. 4-5 (2021): 352–53. http://dx.doi.org/10.1515/olzg-2021-0106.

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Gupta, Sakshi, Preeti Tiwari, Priyanka Srivastava, et al. "Source apportionment and health risk assessment of PM 10 bound carbonaceous and elemental species in the central Himalayas." Current Natural Sciences and Engineering 1, no. 2 (2024): 15–26. http://dx.doi.org/10.63015/2e-2418.1.2.

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In this extensive investigation, the sources and health risk assessment of carbonaceous aerosols, as well as the elemental compositions (Ca, Al, Fe, S, K, Mg, Pd, B, Mo, Zn, Ag, Nb, Ga, Cl, Ti, Zr, Na, Cr, Cu, Mn, Cs, P, Y, Sb, Ni, Sn, F, Sr, Br, Pm, U, Pb, Th, Br, Rb, and V) of PM10, were conducted throughout January-December 2021 in Nainital, a central Himalayan region of India. The average annual mass concentration of PM10 was determined to be 64±6 µg m-3. Carbonaceous aerosols (CAs), comprising OC, EC, WSOC, and SOC, exhibited annual averages of 9.3±0.8 µg m-3, 4.9±0.5 µg m-3, 1.5±0.2 µg m

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Fidias, P., T. A. Ciuleanu, O. Gladkov, et al. "A randomized, open-label, phase III trial of NOV-002 in combination with paclitaxel (P) and carboplatin (C) versus paclitaxel and carboplatin alone for the treatment of advanced non-small cell lung cancer (NSCLC)." Journal of Clinical Oncology 28, no. 18_suppl (2010): LBA7007. http://dx.doi.org/10.1200/jco.2010.28.18_suppl.lba7007.

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LBA7007 Background: NOV-002 is a formulation of disodium glutathione disulfide (GSSG). GSSG is a naturally occurring substance that functions as a component of the glutathione (GSH) pathway, vital to the regulation of the intracellular redox state. A key function of the GSH/GSSG redox couple is to dynamically regulate protein functions, including cell signaling pathways, through the reversible formation of mixed disulfides between protein cysteines and GSH (S-glutathionylation). Based on positive results from a randomized, phase I/II study of carboplatin and paclitaxel (CP) with or without NOV

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Krogh Andersen, Anne Marie, and Poul Norby. "Ab initio structure determination and Rietveld refinement of a high-temperature phase of zirconium hydrogen phosphate and a new polymorph of zirconium pyrophosphate from in situ temperature-resolved powder diffraction data." Acta Crystallographica Section B Structural Science 56, no. 4 (2000): 618–25. http://dx.doi.org/10.1107/s0108768100003645.

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The collected in situ temperature-resolved synchrotron powder data revealed that the transformation of the recently reported three-dimensional τ-Zr(HPO4)2 to cubic ZrP2O7 goes through two intermediate phases. The first intermediate phase, ρ-Zr(HPO4)2, is formed in a reversible phase transition at 598 K, which involves both rearrangement and disordering of the hydrogen phosphate groups of τ-Zr(HPO4)2. At 688 K condensation of the hydrogen phosphate groups leads to the formation of the second intermediate, a new polymorph of zirconium pyrophosphate (β-ZrP2O7). Heating above 973 K results in the

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Simura, Rayko, та Hisanori Yamane. "α-SrZn5-Type solid solution, BaZn2.6Cu2.4". Acta Crystallographica Section E Crystallographic Communications 75, № 10 (2019): 1490–93. http://dx.doi.org/10.1107/s2056989019012532.

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Single crystals of the title compound barium zinc copper, BaCu2.6Zn2.4, were obtained from a sample prepared by heating metal chips of Ba, Cu, and Zn in an Ar atmosphere up to 973 K, followed by slow cooling. Single-crystal X-ray structure analysis revealed that BaCu2.6Zn2.4 crystallizes in an orthorhombic cell [a = 12.9858 (3), b = 5.2162 (1), and c = 6.6804 (2) Å] with an α-SrZn5-type structure (space group Pnma). The three-dimensional framework consists of Cu and Zn atoms, with Ba atoms in the tunnels extending in the b-axis direction. Although the Ba atom is larger than the Sr atom, the ce

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Ziegler, Raimund, Martina Tribus, Clivia Hejny, and Gunter Heymann. "Single-Crystal Structure of HP-Sc2TeO6 Prepared by High-Pressure/High-Temperature Synthesis." Crystals 11, no. 12 (2021): 1554. http://dx.doi.org/10.3390/cryst11121554.

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The first high-pressure scandium tellurate HP-Sc2TeO6 was synthesized from an NP-Sc2TeO6 normal-pressure precursor at 12 GPa and 1173 K using a multianvil apparatus (1000 t press, Walker-type module). The compound crystallizes in the monoclinic space group P2/c (no. 13) with a = 729.43(3), b = 512.52(2), c = 1095.02(4) pm and β = 103.88(1)°. The structure was refined from X-ray single-crystal diffractometer data: R1 = 0.0261, wR2 = 0.0344, 568 F2 values and 84 variables. HP-Sc2TeO6 is isostructural to Yb2WO6 and is built up from TeO6 octahedra, typical for tellurate(VI) compounds. During synth

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Silfiani, Intan, Abdul Latief Abadi, Luqman Qurata Aini, Kestrillia Rega Prillianti, Matheus Randy Prabowo, and Sylvia Herli Dianti. "FTIR (Fourier Transform Infrared) Spectroscopy Method for Bacillus cereus Characterization." Research Journal of Life Science 9, no. 2 (2022): 69–76. http://dx.doi.org/10.21776/ub.rjls.2022.009.02.3.

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One of the potentials of Bacillus cereus bacteria is as an inducer of systemic resistance in plants against plant diseases. FTIR spectroscopy is a traditional method extensively utilized in the pharmaceutical industry, since it is fast, non-destructive, and requires minimal sample preparation. In this study, the indicators that were effectively discovered were the functional groups that compose carbohydrates and lipids. The absorption region to be analyzed for the functional groups that compose carbohydrates is in the wavenumber region of 1200-800 cm-1, whereas the functional groups that compo

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Sato, Hiroshi. "Liquidus Surfaces and Isothermal Section at 973 K of the BaO-ZnO-B₂O₃ Pseudo-Ternary System." MATERIALS TRANSACTIONS 47, no. 12 (2006): 2910–17. http://dx.doi.org/10.2320/matertrans.47.2910.

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Chin, K., H. Iishi, H. Imamura, et al. "Irinotecan plus S-1 (IRIS) versus S-1 alone as first line treatment for advanced gastric cancer: Preliminary results of a randomized phase III study (GC0301/TOP-002)." Journal of Clinical Oncology 25, no. 18_suppl (2007): 4525. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.4525.

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4525 Background: Irinotecan has single agent activity and combination activity with S-1 reportedly in phase I/II studies with advanced gastric cancer patients (pts). S-1, oral fluoropyrimidine, also has activity on gastric cancer. A multicenter, randomized phase III trial comparing IRIS to S-1 alone in advanced gastric cancer was conducted. Methods: Pts with previously untreated gastric cancer were randomized to Arm A (oral S-1 80 mg/m2/day from day 1 to 28 followed by a 14-day rest period), or Arm B (oral S-1 80 mg/m2/day from day 1 to 21 and intravenous irinotecan 80 mg/m2 on days 1 and 15 f

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Funnell, Mark P., Stephen A. Mears, Kurt Bergin-Taylor, and Lewis J. James. "Blinded and unblinded hypohydration similarly impair cycling time trial performance in the heat in trained cyclists." Journal of Applied Physiology 126, no. 4 (2019): 870–79. http://dx.doi.org/10.1152/japplphysiol.01026.2018.

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Knowledge of hydration status may contribute to hypohydration-induced exercise performance decrements; therefore, this study compared blinded and unblinded hypohydration on cycling performance. Fourteen trained, nonheat-acclimated cyclists (age: 25 ± 5 yr; V̇o2peak: 63.3 ± 4.7 ml·kg−1·min−1; cycling experience: 6 ± 3 yr) were pair matched to blinded (B) or unblinded (UB) groups. After familiarization, subjects completed euhydrated (B-EUH; UB-EUH) and hypohydrated (B-HYP; UB-HYP) trials in the heat (31°C); 120-min cycling preload (50% Wpeak) and a time trial (~15 min). During the preload of all

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Dasari, Arvind, Joleen M. Hubbard, Cathy Eng, et al. "Phase 1/1b trial of fruquintinib in patients with advanced solid tumors: Preliminary results of the dose expansion cohorts in refractory metastatic colorectal cancer." Journal of Clinical Oncology 40, no. 4_suppl (2022): 93. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.093.

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93 Background: Fruquintinib (F) is a highly selective, novel, oral tyrosine kinase inhibitor (TKI) of vascular endothelial growth factor receptors (VEGFR) -1, -2, and -3. The phase (Ph) 3 FRESCO study (NCT02314819) that investigated F (5mg daily, 3 weeks (wks) on 1 wk off) showed improved median overall survival in patients (pts) with metastatic colorectal cancer (mCRC) in third line and beyond when compared to placebo (9.3 vs. 6.6 months); hazard ratio 0.65 (P < 0.001) and led to its approval in China. Methods: This is an ongoing Ph 1/1b open-label, dose escalation/expansion study conducte

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Pryor, J. Luke, Evan C. Johnson, Jeffery Del Favero, Andrew Monteleone, Lawrence E. Armstrong, and Nancy R. Rodriguez. "Hydration Status and Sodium Balance of Endurance Runners Consuming Postexercise Supplements of Varying Nutrient Content." International Journal of Sport Nutrition and Exercise Metabolism 25, no. 5 (2015): 471–79. http://dx.doi.org/10.1123/ijsnem.2014-0231.

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Postexercise protein and sodium supplementation may aid recovery and rehydration. Preserved beef provides protein and contains high quantities of sodium that may alter performance related variables in runners. The purpose of this study was to determine the effects of consuming a commercial beef product postexercise on sodium and water balance. A secondary objective was to characterize effects of the supplementation protocols on hydration, blood pressure, body mass, and running economy. Eight trained males (age = 22 ± 3 y, V̇O2max = 66.4 ± 4.2 ml·kg-1·min-1) completed three identical weeks of r

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Barber, Madyson G., Andrew W. Mann, Jonathan L. Bush, et al. "Transit Hunt for Young and Maturing Exoplanets (THYME). VIII. A Pleiades-age Association Harboring Two Transiting Planetary Systems from Kepler." Astronomical Journal 164, no. 3 (2022): 88. http://dx.doi.org/10.3847/1538-3881/ac7b28.

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Abstract Young planets provide a window into the early stages and evolution of planetary systems. Ideal planets for such research are in coeval associations, where the parent population can precisely determine their ages. We describe a young association (MELANGE-3) in the Kepler field, which harbors two transiting planetary systems (KOI-3876 and Kepler-970). We identify MELANGE-3 by searching for kinematic and spatial overdensities around Kepler planet hosts with high levels of lithium. To determine the age and membership of MELANGE-3, we combine new high-resolution spectra with archival light

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Graves, Diana, Aleksandar Obradovic, Michael Korrer, et al. "903 Human cancer-associated fibroblast subsets can predict immune checkpoint response in head and neck cancer patients." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (2021): A947. http://dx.doi.org/10.1136/jitc-2021-sitc2021.903.

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BackgroundUse of anti-PD-1 immune checkpoint inhibitors (ICI) is currently the first line therapy for recurrent/metastatic head and neck squamous cell carcinoma (HNSCC), but critical work remains in identifying factors guiding resistance mechanisms.1 2 While recent studies have specifically implicated cancer-associated fibroblasts (CAFs) as potential mediators of immunotherapy response, the immunoregulatory role of CAFs in head and neck cancer has not been thoroughly explored.3–5MethodsTo determine if there are changes in cell populations associated with anti-PD-1 therapy in head and neck canc

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Torgashina, A., E. Sokol, J. Khvan, et al. "OP0320 CHARACTERISTICS OF PERIPHERAL BLOOD B-CELL SUBSETS IN PATIENTS WITH SJOGREN SYNDROME." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 196.1–196. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2982.

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Background:B-cells play a pivotal role in primary Sjogren’s syndrome (SS) pathogenesis. Recent studies have shown disturbances in the peripheral B cell populations in primary SS.Objectives:To examine В-cell subsets in peripheral blood of SS patients (pts) and to analyze the association between B-cell subsets and SS activity.Methods:Twenty active SS pts (19F/1M): median age 42 years (range) (32-54); disease duration 3 (2-10) years; ESSDAI score ≥5 in 6 pts, <5 in 14 pts), were included. SS was diagnosed based on the ACR-EULAR 2016 criteria. Twenty healthy donors composed the control group. C

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Kushkhov, Kh B., F. A. Kisheva, M. K. Vindizheva, R. A. Mukozheva, K. R. Kozhemova, and L. M. Beroeva. "INVESTIGATION OF THE MECHANISM OF LANTHANUM IONS ELECTROREDUCTION ON NICKEL ELECTRODE IN CHLORIDE MELT." Расплавы, no. 6 (November 1, 2023): 652–60. http://dx.doi.org/10.31857/s023501062306004x.

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The electrochemical behavior of lanthanum ions on a nickel electrode has been studied using various electrochemical methods such as cyclic voltammetry, chronopotentiometry, open circuit chronopotentiometry (on-off curves), and square wave voltammetry in an equimolar melt of potassium and sodium chlorides at 973 K. The cyclic voltammetry curves has several reduction waves on the cathodic branch and corresponding oxidation waves on the anodic branch. The first wave A is located in the potential region –(0.0–0.1) V, where the reduction of Ni2+ ions takes place. The second wave B is in the region

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ALMEIDA, LUIZ EDUARDO PEREIRA COSTA ASSIS DE, LUIS EDUARDO CARELLI TEIXEIRA DA SILVA, CAIQUE JAUHAR DE CASTRO, GIULIANA VASCONCELOS DE SOUZA FONSECA, ROBSON TEIXEIRA VITAL, and MÁRCIA MARIA RODRIGUES JARDIM. "PEDICLE MORPHOLOGY IN SCOLIOSIS: CLASSIFICATION AGREEMENT FOR PRE-OPERATIVE EVALUATION." Coluna/Columna 19, no. 3 (2020): 176–79. http://dx.doi.org/10.1590/s1808-185120201903224254.

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ABSTRACT Objectives Although Watanabe morphological classification is well known, there is no consensus of its use among spine surgeons. We propose an analysis of the Watanabe classification by three observers, one senior and two recently graduated orthopedic spine surgeons, and its applicability in pre-operative evaluation. Methods An intraobserver and interobserver analysis of the classifications of 937 thoracic pedicles among 55 scoliosis patients treated surgically in two institutions. The average age at time of surgery was 16.3 years (10- 50 years). The etiologies of the scoliosis were: i

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Shao, Yu Yun, Chi-Huang Hsiao, Ray Lee, et al. "Tumor c-Met expression and prognosis of advanced hepatocellular carcinoma patients treated with sorafenib." Journal of Clinical Oncology 33, no. 3_suppl (2015): 317. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.317.

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317 Background: Overexpression of c-Met signaling has been associated with development and progression of hepatocellular carcinoma (HCC). We explored the prognostic role of tumor c-Met expression in patients with advanced HCC. Methods: Patients who had received sorafenib alone as first-line therapy for advanced HCC and had available archival tumor tissues were enrolled. Expression of total c-Met was determined by immunohistochemical staining using CONFIRM anti-total c-MET (SP44) rabbit monoclonal primary antibody (Ventana) on the BenchMark ULTRA staining platform. We evaluated c-Met expression

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Samad, Abdul, D. D. Solihin, D. D. Solihin, et al. "Phylogeography of the Maleo Senkawor (Macrocephalon maleo Sal. Muller 1846) Based on Cytochrome B Gene in Sulawesi And Their Sex Determination using Molecular Sexing." Jurnal Ilmu Ternak dan Veteriner 28, no. 1 (2023): 34–44. http://dx.doi.org/10.14334/jitv.v28i1.3107.

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The Maleo Senkawor bird (Macrocephalon maleo) is endemic and widely distributed in Sulawesi. Maleo Senkawor bird is monomorphic so it is difficult to distinguish between male and female individuals. This study aimed to determine the kinship relationship among M. maleo in various geographic areas in Sulawesi through the use of the gene marker Cytochrome-b (Cyt-b), determine the sex ratio, and examine the reliability of the 2550F/2718R primer. Fifteen (feather and eggshell) samples from North Sulawesi, Southeast Sulawesi, and Central Sulawesi were collected. Total DNA isolation was performed usi

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Zoladek, T., G. Vaduva, L. A. Hunter, et al. "Mutations altering the mitochondrial-cytoplasmic distribution of Mod5p implicate the actin cytoskeleton and mRNA 3' ends and/or protein synthesis in mitochondrial delivery." Molecular and Cellular Biology 15, no. 12 (1995): 6884–94. http://dx.doi.org/10.1128/mcb.15.12.6884.

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The Saccharomyces cerevisiae MOD5 gene encodes proteins that function in three subcellular locations: mitochondria, the cytoplasm, and nuclei (M. Boguta, L.A. Hunter, W.-C. Shen, E. C. Gillman, N. C. Martin, and A. K. Hopper, Mol. Cell. Biol. 14:2298-2306, 1994; E. C. Gillman, L. B. Slusher, N. C. Martin, and A. K. Hopper, Mol. Cell. Biol. 11:2382-2390, 1991). A mutant allele of MOD5 encoding a protein (Mod5p-I,KR6) located predominantly in mitochondria was constructed. Mutants defective in delivering Mod5p-I,KR6 to mitochondria were sought by selecting cells with increased cytosolic activity

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Orrú, C., V. Chavarrías, W. S. J. Uijttewaal, and A. Blom. "Image analysis for measuring stratigraphy in sand-gravel laboratory experiments." Earth Surface Dynamics Discussions 1, no. 1 (2013): 973–1018. http://dx.doi.org/10.5194/esurfd-1-973-2013.

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Abstract. Measurements of spatial and temporal changes in the grain size distribution are crucial to improving the modelling of sediment transport and associated grain size-selective processes. We present three complementary techniques to determine such variations in the grain size distribution in sand-gravel laboratory experiments, as well as the resulting stratigraphy: (1) particle colouring, (2) removal of sediment layers, and (3) image analysis. The resulting stratigraphy measurement method has been evaluated in two sets of experiments. In both sets three grain size fractions within the ra

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Lapierre, Jean-Marc, Sudharshan Eathiraj, David Vensel, et al. "Discovery of 3-(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine (ARQ 092): An Orally Bioavailable, Selective, and Potent Allosteric AKT Inhibitor." Journal of Medicinal Chemistry 59, no. 13 (2016): 6455–69. http://dx.doi.org/10.1021/acs.jmedchem.6b00619.

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Bindi, L., F. Nestola, E. Makovicky, A. Guastoni, and L. De Battisti. "Tl-bearing sulfosalt from the Lengenbach quarry, Binn Valley, Switzerland: Philrothite, TlAs3S5." Mineralogical Magazine 78, no. 1 (2014): 1–9. http://dx.doi.org/10.1180/minmag.2014.078.1.01.

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AbstractPhilrothite, ideally TlAs3S5, is a new mineral from the Lengenbach quarry in the Binn Valley, Valais, Switzerland. It occurs as very rare crystals up to 200 mm across on realgar associated with smithite, rutile and sartorite. Philrothite is opaque with a metallic lustre and shows a dark brown streak. It is brittle; the Vickers hardness (VHN25) is 128 kg/mm2 (range: 120–137) (Mohs hardness of 3–3½). In reflected light philrothite is moderately bireflectant and weakly pleochroic from dark grey to light grey. Under crossed polars it is anisotropic with grey to bluish rotation tints. Inter

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Hannemann. "Schmidt, G. (Hrsg.): Sozialpolymorphismus bei Insekten. Probleme der Kastenbildung im Tierreich. Studienausgabe. 2. unveränderte Aufl. 1987. XXIV, 974 S., 281 Abbild., 83 Tab., kart. DM 78. – Wissenschaftliche Verlagsges. m. b. H. Stuttgart. ISBN 3-8047-0942-7." Deutsche Entomologische Zeitschrift (neue Folge) 35, no. 1-3 (1988): 215. http://dx.doi.org/10.1002/mmnd.4810350137.

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Wu, Shaojie, Junru Du, Jie Ma, et al. "A Survival Prognostic Model for Gastro-Intestinal Non-Hodgkin Lymphoma." Blood 144, Supplement 1 (2024): 3087. https://doi.org/10.1182/blood-2024-200667.

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Primary gastro-intestinal lymphoma is the most common extra-nodal lymphoma. There is no widely-accepted survival prognostic model. We interrogated data from 1, 023 consecutive newly-diagnosed subjects. The most common site was stomach (n = 560, 54.74%) followed by the large intestine (excluding the ileocecal region) (n = 177, 17.30%), small intestine (n = 134, 13.10%), ileocecal region (n = 85, 8.31%). Most were of B-cell origin (n = 973, 95.1%). Diffuse large B-cell lymphoma (DLBCL) was the most common diagnosis (n = 668, 65.30%). Subjects with B-cell non-Hodgkin lymphoma had better survival

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Bongomin, Felix, Tomaz Garcez, and David W. Denning. "Impact of high baseline Aspergillus-specific IgG levels on weight and quality-of-life outcomes of patients with chronic pulmonary aspergillosis." Medical Mycology 58, no. 7 (2020): 1000–1004. http://dx.doi.org/10.1093/mmy/myaa026.

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Abstract This study aimed to evaluate the impact of quantitative baseline Aspergillus-specific immunoglobulin G (IgG) serum levels on weight changes of patients with chronic pulmonary aspergillosis (CPA) under antifungal treatment. We retrospectively reviewed data of patients diagnosed with CPA between April 2015 and March 2018 at the National Aspergillosis Centre (Manchester, UK). All patients were on continued antifungal treatment for 12 months. Data on Aspergillus-specific IgG levels, St George's quality of life (SGQoL) variables and weight at baseline, 6 months and 12 months were extracted

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Bedenne, Laurent, Pierre Michel, Olivier Bouché, et al. "Chemoradiation Followed by Surgery Compared With Chemoradiation Alone in Squamous Cancer of the Esophagus: FFCD 9102." Journal of Clinical Oncology 25, no. 10 (2007): 1160–68. http://dx.doi.org/10.1200/jco.2005.04.7118.

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Purpose Uncontrolled studies suggest that chemoradiation has similar efficacy as surgery for esophageal cancer. Therefore, a randomized trial was carried out to compare, in responders only, chemoradiation alone with chemoradiation followed by surgery in patients with locally advanced tumors. Patients and Methods Eligible patients had operable T3N0-1M0 thoracic esophageal cancer. Patients received two cycles of fluorouracil (FU) and cisplatin (days 1 to 5 and 22 to 26) and either conventional (46 Gy in 4.5 weeks) or split-course (15 Gy, days 1 to 5 and 22 to 26) concomitant radiotherapy. Patien

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Norikawa, Yutaro, Kouji Yasuda, and Toshiyuki Nohira. "Effect of Temperature on Grain Growth during Ti Electrodeposition in Lif–LiCl Eutectic Melt." ECS Meeting Abstracts MA2022-01, no. 23 (2022): 1197. http://dx.doi.org/10.1149/ma2022-01231197mtgabs.

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1. Introduction Ti has superior properties, such as high specific strength, corrosion resistance, biocompatibility, and is used for many fields such as airplane, chemical plant, consumer products. However, its high manufacturing cost and poor processability have hindered its further spread. Thus, a number of smelting processes and processing methods have been investigated to reduce the cost and spread the use of Ti. Among them, plating Ti metal on inexpensive substrates is one of the methods that can utilize the surface properties of Ti. Electrodeposition is a promising plating method from the

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Kuo, Hung-Yang, Jhe-Cyuan Guo, Ta-Chen Huang, et al. "The recurrence patterns and post-recurrence survivals in patients with locally advanced esophageal squamous cell carcinoma (ESCC) treated with preoperative paclitaxel/cisplatin-based chemoradiotherapy." Journal of Clinical Oncology 34, no. 4_suppl (2016): 80. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.80.

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80 Background: More than half of patients (pts) with locally advanced ESCC would have disease recurrence after curative preoperative chemoradiation (CRT) followed by surgery. Whether recurrence pattern correlates with the post-recurrence survival remains uncertain. Methods: We included 131 pts with locally advanced ESCC (clinical T3N0-1M0 or T1-3N1M0 or M1a according to AJCC 6thedition) who were enrolled in 3 phase II clinical trials of preoperative CRT followed by surgery and had successfully completed CRT and surgery. These pts received preoperative twice weekly paclitaxel/cisplatin-based CR

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NAVNIT KUMAR, LALITA RANA, and A.K. SINGH. "Response of high yielding varieties of sugarcane (Saccharum spp. hybrid complex) to planting materials under waterlogged condition." Indian Journal of Agronomy 69, no. 2 (2024): 190–94. http://dx.doi.org/10.59797/ija.v69i2.5506.

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A 3 -years field experiment consisting of 2 planting materials viz., 3- bud setts and bud chips and 5 sugarcane (Saccharum spp. hybrid complex) varieties (‘BO 91’, ‘CoP 16437’, ‘CoP 16438’ and ‘BO 156’) was conducted during spring seasons of 2016-17, 2017-18 and 2018-19, to study the effect of planting materials and varieties on productivity of sugarcane under waterlogged conditions. Significantly higher plant population (157, 000/ha), plant height (292 cm), LAI (4.12), mortality percent (38.4%), length of internode (11.8 cm), millable canes (96, 300/ha) and B: C ratio (0.70) was observed with

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Sarmistha, Halder, Paul Piyali, Acharyya Rama, et al. "Cytotoxic properties of two families of benzaldehyde thiosemicarbazone complexes of palladium." Journal of Indian Chemical Society Vol. 90, Jun 2013 (2013): 771–76. https://doi.org/10.5281/zenodo.5772639.

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Department of Chemistry, Inorganic Chemistry Section, Jadavpur University, Kolkata-700 032, India <em>E-mail </em>: samaresh _ b@hotmal.J. com Department of Anticancer Drug Development, Chittaranjan National Cancer Institute, Kolkata-700 026, India <em>Manuscript received online 16 July 2012. accepted 20 July 2012</em> Reaction of 4-R-benzaldehy thiosermicarbazones (HL-R, where H stands for the dissociable hydrazinic proton- and R (R = OCH<sub>3</sub>, CH<sub>3</sub>, H, Cl and NO<sub>2</sub>) for the substituent) with <em>trans</em>-[Pd(PPh<sub>3</sub>)<sub>2</sub>CI<sub>2</sub>] and Na<

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Krakers, Sanne, Sanne Woudsma, Dieuwke van Dartel, Marloes Vermeer, Miriam Vollenbroek-Hutten, and Johannes Hegeman. "Rehabilitation of Frail Older Adults after Hip Fracture Surgery: Predictors for the Length of Geriatric Rehabilitation Stay at a Skilled Nursing Home." Journal of Clinical Medicine 13, no. 15 (2024): 4547. http://dx.doi.org/10.3390/jcm13154547.

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Background: Approximately 50% of older patients hospitalized for hip fractures are admitted to a geriatric rehabilitation department at a skilled nursing home. Given the wide variation in rehabilitation stay lengths, predicting the length of stay upon hospital discharge would help manage patients’ recovery expectations and create appropriate therapy schedules. Existing literature on length of stay predictors included both acute hospital and in-hospital rehabilitation phases or involved small sample sizes. The present study aims to identify predictors for the length of geriatric rehabilitation

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Tee, Vanessa Sze Theen, Phan Nguyen, Hubertus Jersmann, et al. "Use of Ventilation-Perfusion Single-Photon Emission Computed Tomography to Select the Target Lobe for Endobronchial Valve Lung Volume Reduction." Respiration 100, no. 9 (2021): 886–97. http://dx.doi.org/10.1159/000515336.

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<b><i>Background:</i></b> Quantitative planar ventilation-perfusion (VQ) has a complementary role in target lobe selection for endobronchial valve lung volume reduction (EBV-LVR), especially in homogenous disease. We investigated a novel method of lung lobar quantitation using VQ single-photon emission computed tomography (SPECT) with computed tomography (CT) to generate a parameter called the ventilation-perfusion differential index (VQDI). <b><i>Aim:</i></b> The aim of this study was to validate VQDI as a parameter for target lobe selection in

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