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1

Das, Sourav, Barbara Vörös-Horváth, Tímea Bencsik, et al. "Antimicrobial Activity of Different Artemisia Essential Oil Formulations." Molecules 25, no. 10 (2020): 2390. http://dx.doi.org/10.3390/molecules25102390.

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The extreme lipophilicity of essential oils (EOs) impedes the measurement of their biological actions in an aqueous environment. We formulated oil in water type Pickering Artemisia annua EO nanoemulsions (AEP) with surface-modified Stöber silica nanoparticles (20 nm) as the stabilizing agent. The antimicrobial activity of AEP and its effects on mature Candida biofilms were compared with those of Tween 80 stabilized emulsion (AET) and ethanolic solution (AEE) of the Artemisia EO. The antimicrobial activity was evaluated by using the minimum inhibitory concentrations (MIC90) and minimum effectiv
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Ahmad, Ishtiaque, Anjum Khalique, Muhammad Qamar Shahid, et al. "Studying the Influence of Apple Peel Polyphenol Extract Fortification on the Characteristics of Probiotic Yoghurt." Plants 9, no. 1 (2020): 77. http://dx.doi.org/10.3390/plants9010077.

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The aim of the current study was to evaluate the effect of apple peel polyphenol extract (APPE) on the physicochemical and microbiological properties of probiotic yoghurt. Five concentrations of APPE were added in probiotic yoghurt as: (1) CTL, control without APPE; (2) AE1, addition of 1% APPE; (3) AE2, addition of 2% APPE; (4) AE3, addition of 3% APPE; (5) AE4, addition of 4% APPE; and (6) AE5, addition of 5% APPE. The prepared probiotic yoghurt was stored at 4 °C for 21 days and analyzed for physicochemical and microbiological properties. The initial viable count of L. bulgaricus, S. thermo
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Chertoff, Mark E., Kurt E. Hecox, and Robert Goldstein. "Auditory Distortion Products Measured With Averaged Auditory Evoked Potentials." Journal of Speech, Language, and Hearing Research 35, no. 1 (1992): 157–66. http://dx.doi.org/10.1044/jshr.3501.157.

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The purpose of this investigation was to describe the properties of averaged auditory evoked potential distortion products (AEP-DPs) in guinea pigs. This study provided a step toward developing a clinical index of nonlinear processing of auditory signals and supplied a baseline for studies evaluating the effect of cochlear damage on AEP-DPs. The amplitude of the AEP-DPs was evaluated as a function of f2/fl ratio (1.12–1.52) and primary frequency (500 Hz–2000 Hz). The amplitude of the AEP cubic difference tone (AEP-CDT) increased with increasing f2/fl ratio for the 500-Hz f1 primary and remaine
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Schwarz, G., J. Brandenburg, M. Reich, T. Burster, C. Driessen, and H. Kalbacher. "Characterization of Legumain." Biological Chemistry 383, no. 11 (2002): 1813–16. http://dx.doi.org/10.1515/bc.2002.203.

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Abstract The mammalian legumain, also called asparaginyl endopeptidase (AEP), is critically involved in the processing of bacterial antigens for MHC class II presentation. In order to investigate the substrate specificity of AEP in the P1 position, we created a peptide library and digested it with purified pig kidney AEP. Digestion was less efficient only when proline was in the P1 position. Maximum AEP activity was found in lysosomal fractions of different types of antigen presenting cells (APC). When the multiple sclerosisassociated autoantigen myelin basic protein (MBP) was digested with AE
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5

Sedval, Göran. "AEP President’s Report." European Psychiatry 17, no. 4 (2002): 175–78. http://dx.doi.org/10.1016/s0924-9338(02)00670-3.

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6

Meneu, Ricard. "¿AEP para qué?" Revista de Calidad Asistencial 17, no. 8 (2002): 589–90. http://dx.doi.org/10.1016/s1134-282x(02)77549-0.

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7

Zhang, Wenrui, and Yingying Lin. "The Mechanism of Asparagine Endopeptidase in the Progression of Malignant Tumors: A Review." Cells 10, no. 5 (2021): 1153. http://dx.doi.org/10.3390/cells10051153.

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Asparagine endopeptidase (AEP), also called legumain, is currently the only known cysteine protease that specifically cleaves peptide bonds in asparaginyl residue in the mammalian genome. Since 2003, AEP has been reported to be widely expressed in a variety of carcinomas and is considered a potential therapeutic target. In the following years, researchers intensively investigated the substrates of AEP and the mechanism of AEP in partial tumors. With the identification of substrate proteins such as P53, integrin αvβ3, MMP-2, and MMP-9, the biochemical mechanism of AEP in carcinomas is also more
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8

Schneider, Gerhard, Eberhard F. Kochs, Henry Arenbeck, Michael Gallinat, and Gudrun Stockmanns. "Signal Verification of Middle Latency Auditory Evoked Potentials by Automated Detection of the Brainstem Response." Anesthesiology 101, no. 2 (2004): 321–26. http://dx.doi.org/10.1097/00000542-200408000-00012.

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Background The midlatency components of auditory evoked potentials (AEPs) are gradually suppressed with increasing concentrations of anesthetics. Thus, they have been proposed as a monitor of anesthetic depth. However, undetected malfunction or disconnection of headphones and undetected hearing loss also result in suppressed midlatency AEPs that in turn may be misinterpreted as signs of deep anesthesia. As the brainstem component of the AEP is minimally influenced by anesthetics, its presence or absence can be used to verify that the recorded signal is a true AEP rather than an artifact. In th
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9

peng, baowei, Bin Lan та Fang Guo. "Loss of asparagine endopeptidase impairs autophagic degradation and enhances endotoxin-induced TNF-α production in M2 macrophages (INM8P.358)". Journal of Immunology 194, № 1_Supplement (2015): 195.2. http://dx.doi.org/10.4049/jimmunol.194.supp.195.2.

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Abstract Asparagine endopeptidase (AEP) has been shown to play important roles in innate immunity. Here, we show that AEP is a previously unrecognized regulator of autophagy in M2 macrophages. AEP interacted with PI3K p110α and suppressed PI3K activation on the endomembranes. AEP deficiency led to abnormal activation of PI3K, which converted phosphatidyinositol (4,5)-bisphosphate (PIP2) to phosphatidyinositol (3,4,5)-bisphosphate (PIP3) (PIP3). Decrease in PIP2 and increase in PIP3 resulted in impaired autophagic lysosome biogenesis and autolysosome clearance. Impaired autolysosome clearance i
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10

Jacob, Stefan, and Christian Koch. "Unveiling weak auditory evoked potentials using data-driven filtering." Journal of the Acoustical Society of America 154, no. 4_supplement (2023): A141. http://dx.doi.org/10.1121/10.0023054.

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Auditory evoked potentials (AEPs) are commonly used to objectively evaluate sound perception in humans. Close to the hearing threshold and for low frequencies, efficient filtering of AEP from other brain activities is of major concern due to weak potentials and the requirement of long averaging times. Filtered AEP data are well-interpretable and useful, especially in medical and psychological diagnostics. Here, we present two data-driven approaches for efficient AEP filtering. First, neural networks of different architectures trained for EEG denoising are used to extract weak late-response AEP
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11

Burina, Adnan, Osman Sinanović, Dževdet Smajlović, Mirjana Vidović, and Fuad Brkić. "Some Aspects of Balance Disorder in Patients with Multiple Sclerosis." Bosnian Journal of Basic Medical Sciences 8, no. 1 (2008): 80–85. http://dx.doi.org/10.17305/bjbms.2008.3003.

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The aim of this study was to analyze: frequency of balance disorder (vertigo and disequilibrium), frequency of abnormalities in auditory evoked potentials (AEP) and magnetic resonance imaging (MRI) changes of the brain in multiple sclerosis (MS) patients with balance disorder, relation of patients disability status to balance disorder and relation of the changes in MRI of the brainstem to AEP abnormalities. It was analyzed 60 patients with relapsing-remitting form of MS. Two groups of patients were made consecutively under Expanded Disability Status Scale score (EDSS): A (EDSS <4,5) and B (
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12

Patel, Naina, Shekhar Krishnan, Marc N. Offman, et al. "Lymphoblasts Produce a Lysosomal Protease That Rapidly Degrades L-Asparaginase - Implications for Therapy in Childhood Acute Lymphoblastic Leukemia." Blood 110, no. 11 (2007): 2791. http://dx.doi.org/10.1182/blood.v110.11.2791.2791.

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Abstract The efficacy of the key anti-leukaemic agent E.coli L-Asparaginase (L-Asp) is limited by variable therapeutic activity and development of antibodies/hypersensitivity. Observing more frequent clinical hypersensitivity in children with high risk acute lymphoblastic leukaemia (ALL), we speculated that L-Asp was proteolytically degraded by lymphoblasts, generating immunogenic fragments. On incubation with whole cell lysate from a lymphoblastic cell line, L-Asp was cleaved into at least three fragments. This cleavage was blocked only by MV026630, a specific inhibitor of the cysteine protea
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Zhang, Fan, Ying Wu, Xiaohan Zou, Qinglian Tang, Fang Zhao, and Zhengyu Cao. "BmK AEP, an Anti-Epileptic Peptide Distinctly Affects the Gating of Brain Subtypes of Voltage-Gated Sodium Channels." International Journal of Molecular Sciences 20, no. 3 (2019): 729. http://dx.doi.org/10.3390/ijms20030729.

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BmK AEP, a scorpion peptide purified form the venom of Buthus martensii Karsch, has been reported to display anti-epileptic activity. Voltage-gated sodium channels (VGSCs) are responsible for the rising phase of action potentials (APs) in neurons and, therefore, controlling neuronal excitability. To elucidate the potential molecular mechanisms responsible for its anti-epileptic activity, we examined the influence of BmK AEP on AP firing in cortical neurons and how BmK AEP influences brain subtypes of VGSCs (Nav1.1–1.3 and Nav1.6). BmK AEP concentration-dependently suppresses neuronal excitabil
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14

Yaver, D. S., S. Matoba, and D. M. Ogrydziak. "A mutation in the signal recognition particle 7S RNA of the yeast Yarrowia lipolytica preferentially affects synthesis of the alkaline extracellular protease: in vivo evidence for translational arrest." Journal of Cell Biology 116, no. 3 (1992): 605–16. http://dx.doi.org/10.1083/jcb.116.3.605.

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Replacement of the signal recognition particle (SRP) 7S gene (SCR1) on a replicating plasmid with scr1-1 (G to A at 129 and A to T at 131 in the consensus sequence -GNAR- in the loop of domain III) resulted in temperature sensitivity for growth of cells in which both chromosomal SRP 7S RNA genes were deleted. Pulse-chase immunoprecipitation experiments were done after a shift to non-permissive temperature using the major secreted protein the alkaline extracellular protease (AEP) as a reporter molecule. No untranslocated AEP precursor was detected in a strain with scr1-1 on a plasmid, but the a
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15

Rachid, Mohamad, Khansa Ahmad, Meghan Saunders-Kurban, Aelia Fatima, Aditya Shah, and Anas Nahhas. "Daptomycin-Induced Acute Eosinophilic Pneumonia: Late Onset and Quick Recovery." Case Reports in Pulmonology 2017 (2017): 1–4. http://dx.doi.org/10.1155/2017/8525789.

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Background. Daptomycin is a cyclic lipopeptide antibiotic that provides great coverage for gram positive cocci. From the early years of daptomycin use, concerns were raised regarding the pulmonary side effects of daptomycin and potential development of acute eosinophilic pneumonia (AEP) secondary to daptomycin therapy. Discussion. AEP could be idiopathic or induced by drugs or toxins. It is a distinct entity from atopic diseases and autoimmune, parasitic, or fungal infections that can also cause pulmonary eosinophilia. Multiple medications are associated with acute eosinophilic pneumonia. Mult
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Lin, Yingying, Keman Liao, Yifeng Miao, et al. "Role of Asparagine Endopeptidase in Mediating Wild-Type p53 Inactivation of Glioblastoma." JNCI: Journal of the National Cancer Institute 112, no. 4 (2019): 343–55. http://dx.doi.org/10.1093/jnci/djz155.

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Abstract Background Isocitrate dehydrogenase wild-type (WT) glioblastoma (GBM) accounts for 90% of all GBMs, yet only 27% of isocitrate dehydrogenase WT-GBMs have p53 mutations. However, the tumor surveillance function of WT-p53 in GBM is subverted by mechanisms that are not fully understood. Methods We investigated the proteolytic inactivation of WT-p53 by asparaginyl endopeptidase (AEP) and its effects on GBM progression in cancer cells, murine models, and patients’ specimens using biochemical and functional assays. The sera of healthy donors (n = 48) and GBM patients (n = 20) were examined
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17

Silva, André Luís Silva da, Marcello Ferreira, Samara Magalhães Pereira, and Olavo Leopoldino da Silva Filho. "Atividade experimental problematizada (AEP)." Revista Pesquisa e Debate em Educação 9, no. 1 (2019): 459–71. http://dx.doi.org/10.34019/2237-9444.2019.v9.31125.

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O ensino experimental fundamentado na busca por solução de problemas baseia-se, sobretudo, na relação estabelecida entre os desafios e a busca de estratégias particularizadas para cercá-los a determinada maneira. Temos trabalhado nesta área de pesquisa nos últimos anos, investigando abordagens experimentais problematizadas (AEP). Muito se tem produzido neste campo científico, sob diversos vieses, e este trabalho se dedica a analisar determinado extrato da produção acadêmica correlata. Foram analisados 12 periódicos científicos nas áreas de Ensino, Educação, Ensino de Química e Ensino de Física
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18

Marsico, R., R. D. Ryan, and R. L. Retallack. "AEP Chainette Structure Development." IEEE Power Engineering Review PER-5, no. 10 (1985): 44. http://dx.doi.org/10.1109/mper.1985.5528699.

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19

Pull, C. B., and J. M. Cloos. "Internet strategies for AEP." European Psychiatry 17 (May 2002): 70. http://dx.doi.org/10.1016/s0924-9338(02)80320-0.

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Marsico, R., R. Ryan, and R. Retallack. "Aep Chainette Structure Development." IEEE Transactions on Power Apparatus and Systems PAS-104, no. 10 (1985): 2844–51. http://dx.doi.org/10.1109/tpas.1985.319128.

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21

Mao, Xudong, Hao Chen, Yubing Wang, Xinbo Zhu, and Guohua Yang. "Study on Benzylamine(BZA) and Aminoethylpiperazine(AEP) Mixed Absorbent on Ship-Based Carbon Capture." Molecules 28, no. 6 (2023): 2661. http://dx.doi.org/10.3390/molecules28062661.

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To find suitable absorbents for ship-based carbon capture, the absorption and desorption properties of four mixed aqueous amines based on BZA were investigated, and the results indicated that BZA-AEP had the best absorption and desorption performance. Then, the absorption and desorption properties of different mole ratios of BZA-AEP were tested. The results showed that the average CO2 absorption rate had the highest value at the mole ratio of BZA to AEP of three. The average CO2 desorption rate had the maximum value at the mole ratio of BZA to AEP of one. Three fitted models of the absorption
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22

Yokoyama, Akihiko, and Hiroshi Okuda. "The Molecular Mechanism of Transcriptional Activation By MLL-AEP Fusion Proteins." Blood 126, no. 23 (2015): 2435. http://dx.doi.org/10.1182/blood.v126.23.2435.2435.

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Abstract Chromosomal translocations generate a variety of mixed lineage leukemia (MLL) fusion genes, which cause aggressive leukemia. Although >70 different fusion partners have been identified, the majority of the cases are caused by the chimeric genes of MLL and a component of the AEP co-activator complex (hereafter referred to as AEP), which comprises of AF4 family proteins (e.g. AF4, AF5Q31), ENL family proteins (e.g. ENL, AF9), and the P-TEFb elongation factor. MLL-AEP fusion proteins constitutively activate their target genes by recruiting AEP components to their target chromatin, whe
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Matoba, S., J. Fukayama, R. A. Wing, and D. M. Ogrydziak. "Intracellular precursors and secretion of alkaline extracellular protease of Yarrowia lipolytica." Molecular and Cellular Biology 8, no. 11 (1988): 4904–16. http://dx.doi.org/10.1128/mcb.8.11.4904-4916.1988.

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Processing and secretion of the alkaline extracellular protease (AEP) from the yeast Yarrowia lipolytica was studied by pulse-chase and immunoprecipitation experiments. Over half of newly synthesized AEP was secreted by 6 min. Over 99% of AEP activity which was external to the cytoplasmic membrane was located in the supernatant medium. Polypeptides of 55, 52, 44, 36, and 32 kilodaltons (55K, 52K, 44K, 36K, and 32K polypeptides) were immunoprecipitated from [3H]leucine-labeled cell extracts by rabbit antibodies raised against mature, secreted AEP (32K polypeptide). Experiments with tunicamycin
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Matoba, S., J. Fukayama, R. A. Wing, and D. M. Ogrydziak. "Intracellular precursors and secretion of alkaline extracellular protease of Yarrowia lipolytica." Molecular and Cellular Biology 8, no. 11 (1988): 4904–16. http://dx.doi.org/10.1128/mcb.8.11.4904.

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Processing and secretion of the alkaline extracellular protease (AEP) from the yeast Yarrowia lipolytica was studied by pulse-chase and immunoprecipitation experiments. Over half of newly synthesized AEP was secreted by 6 min. Over 99% of AEP activity which was external to the cytoplasmic membrane was located in the supernatant medium. Polypeptides of 55, 52, 44, 36, and 32 kilodaltons (55K, 52K, 44K, 36K, and 32K polypeptides) were immunoprecipitated from [3H]leucine-labeled cell extracts by rabbit antibodies raised against mature, secreted AEP (32K polypeptide). Experiments with tunicamycin
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Zhang, Shaojie, Xiaohu Lei, Hongjuan Yang, et al. "Investigation of the functional relationship between antecedent rainfall and the probability of debris flow occurrence in Jiangjia Gully, China." Hydrology and Earth System Sciences 28, no. 11 (2024): 2343–55. http://dx.doi.org/10.5194/hess-28-2343-2024.

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Abstract. A larger antecedent effective precipitation (AEP) indicates a higher probability of a debris flow (Pdf) being triggered by subsequent rainfall. Scientific topics surrounding this qualitative conclusion that can be raised include what kinds of variation rules they follow and whether there is a boundary limit. To answer these questions, Jiangjia Gully in Dongchuan, Yunnan Province, China, is chosen as the study area, and numerical calculation, a rainfall scenario simulation, and the Monte Carlo integration method have been used to calculate the occurrence probability of debris flow und
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Taira, Even Akemi, Carolina Ruis Ferrari, Gabriel Carvalho, et al. "Rinsing with Statherin-Derived Peptide Alters the Proteome of the Acquired Enamel Pellicle." Caries Research 55, no. 4 (2021): 333–40. http://dx.doi.org/10.1159/000517959.

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Changes in the proteomic profile of the acquired enamel pellicle (AEP) formed for 3 min or 2 h after rinsing with a peptide containing the 15 N-terminal residues of statherin, with serines 2 and 3 phosphorylated (StatpSpS), were evaluated. Nine volunteers participated in 2 consecutive days. Each day, after professional tooth cleaning, they rinsed for 1 min with 10 mL of phosphate buffer containing 1.88 × 10<sup>−5</sup> M StatpSpS or phosphate buffer only (control). The acquired pellicle formed on enamel after 3 min or 2 h was collected with electrode filter papers soaked in 3% cit
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Mohd Noor, Noorfaizalfarid, Nadhirah Mohd Napi, and Izzati Farzana Ibni Amin. "The Development of Autonomous Examination Paper Application: A Case Study in UiTM Cawangan Perlis." Journal of Computing Research and Innovation 4, no. 2 (2019): 21–30. http://dx.doi.org/10.24191/jcrinn.v4i2.105.

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Examination is a vital role to measure the capabilities of students in their learning. Hence, generating question paper in an effective way is a decisive job for educators in educational institution. Using traditional method, it is monotonous and time consuming. Today, Autonomous Examination Paper (AEP) is used to produce exam paper. Many researchers have proposed effective AEPs to be used by educators. This paper aims to investigate about AEP development and to construct AEP in UiTM Cawangan Perlis. As a result, Ad-Hoc Question Paper Application (AQPA) has been developed using Fisher-Yates al
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Cruz, Edmara Andrade Macedo, Ester Dias Xavier, Geziella Aurea Aparecida Damasceno Souza, et al. "Formação de biofilmes por Staphylococcus aureus multirresistentes isolados de leite de vacas com mastite." Caderno de Ciências Agrárias 13 (October 17, 2021): 1–6. http://dx.doi.org/10.35699/2447-6218.2021.35651.

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Staphylococcus aureus provenientes de leite de vacas com mastite subclínica e fenotipicamente resistentes a antimicrobianos da classe dos beta-lactâmicos foram testadas quanto a capacidade em produzir biofilme. Foi procedido o cultivo e análise em Ágar vermelho congo (CRA) e Teste de Aderência em Placas (AEP). Também foi avaliada a associação entre os testes CRA e AEP e a associação de cada um destes testes com a frequência das cepas potencialmente produtoras de biofilme resistentes aos beta-lactâmicos. Como resultado, 65,2% (15) dos 23 isolados testaram positivo para formação de biofilme em C
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Chen, Chun, Eun Hee Ahn, Seong Su Kang, Xia Liu, Ashfaqul Alam та Keqiang Ye. "Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model". Science Advances 6, № 31 (2020): eaba0466. http://dx.doi.org/10.1126/sciadv.aba0466.

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The gut-brain axis is bidirectional, and gut microbiota influence brain disorders including Alzheimer’s disease (AD). CCAAT/enhancer binding protein β/asparagine endopeptidase (C/EBPβ/AEP) signaling spatiotemporally mediates AD pathologies in the brain via cleaving both β-amyloid precursor protein and Tau. We show that gut dysbiosis occurs in 5xFAD mice, and is associated with escalation of the C/EBPβ/AEP pathway in the gut with age. Unlike that of aged wild-type mice, the microbiota of aged 3xTg mice accelerate AD pathology in young 3xTg mice, accompanied by active C/EBPβ/AEP signaling in the
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Recart, Alejandro, Paul F. White, Agnes Wang, Irina Gasanova, Stephanie Byerly, and Stephanie B. Jones. "Effect of Auditory Evoked Potential Index Monitoring on Anesthetic Drug Requirements and Recovery Profile after Laparoscopic Surgery." Anesthesiology 99, no. 4 (2003): 813–18. http://dx.doi.org/10.1097/00000542-200310000-00011.

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Background The auditory evoked potential (AEP) monitor provides an electroencephalogram-derived index (AAI) that has been reported to correlate with the central nervous system depressant effects of anesthetic drugs. This clinical utility study was designed to test the hypothesis that AAI-guided administration of the maintenance anesthetics and analgesics would improve their titration and thereby provide a faster recovery from general anesthesia. Methods Seventy consenting patients undergoing elective general surgery procedures were randomly assigned to either a control (standard clinical pract
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Jamieson, Nigel B., Donald C. McMillan, Duncan J. F. Brown, and A. Michael Wallace. "Comparison of simple acid-ethanol precipitation with gel exclusion chromatography for measuring leptin binding in serum of normal subjects and cancer patients." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 40, no. 2 (2003): 185–87. http://dx.doi.org/10.1258/000456303763046157.

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Background: In humans, leptin circulates in a free form and is also bound to macromolecules. The aim of the present study was to compare a rapid acid-ethanol precipitation (AEP) method of measuring bound leptin with the more laborious gel exclusion chromatography (GEC) reference procedure. Serum samples collected from healthy subjects and cancer patients were used in this comparison. Methods: AEP and GEC methods for measuring leptin binding in serum (from 14 healthy volunteers and 14 patients with advanced non-small cell lung cancer) were adapted from previously published procedures. Results:
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Gao, Han, Wencheng Zhang, Bingsong Wang, et al. "Purification, characterization and anti-fatigue activity of polysaccharide fractions from okra (Abelmoschus esculentus (L.) Moench)." Food & Function 9, no. 2 (2018): 1088–101. http://dx.doi.org/10.1039/c7fo01821e.

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Padrón, Andrés Santiago, Jared Thomas, Andrew P. J. Stanley, Juan J. Alonso, and Andrew Ning. "Polynomial chaos to efficiently compute the annual energy production in wind farm layout optimization." Wind Energy Science 4, no. 2 (2019): 211–31. http://dx.doi.org/10.5194/wes-4-211-2019.

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Abstract. In this paper, we develop computationally efficient techniques to calculate statistics used in wind farm optimization with the goal of enabling the use of higher-fidelity models and larger wind farm optimization problems. We apply these techniques to maximize the annual energy production (AEP) of a wind farm by optimizing the position of the individual wind turbines. The AEP (a statistic) is the expected power produced by the wind farm over a period of 1 year subject to uncertainties in the wind conditions (wind direction and wind speed) that are described with empirically determined
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Pryor, Sara C., Tristan J. Shepherd, and Rebecca J. Barthelmie. "Interannual variability of wind climates and wind turbine annual energy production." Wind Energy Science 3, no. 2 (2018): 651–65. http://dx.doi.org/10.5194/wes-3-651-2018.

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Abstract. The interannual variability (IAV) of expected annual energy production (AEP) from proposed wind farms plays a key role in dictating project financing. IAV in preconstruction projected AEP and the difference in 50th and 90th percentile (P50 and P90) AEP derive in part from variability in wind climates. However, the magnitude of IAV in wind speeds at or close to wind turbine hub heights is poorly defined and may be overestimated by assuming annual mean wind speeds are Gaussian distributed with a standard deviation (σ) of 6 %, as is widely applied within the wind energy industry. There
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Turkmen, Seref. "Stabilization of the Turkish Economy in the Early 2000s and the Urgent Action Plan." European Scientific Journal, ESJ 19, no. 10 (2023): 64. http://dx.doi.org/10.19044/esj.2023.v19n10p64.

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This article discusses the stabilisation of the Turkish economy in the early 2000s, with a focus on the Urgent Action Plan (AEP) implemented by the Justice and Development Party (AKP). The AEP aimed to bring about real structural changes in Turkish economic governance, accelerate privatization, provide capital to certain productive sectors, and increase financial discipline, resulting in the radical decline of public debt. The article explores the success of the AEP and the impact of the AKP's economic policies on the country's growth, as well as the role of globalization and the European Unio
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Mittraphab, Yanisa, Maki Nagata, Masako Matsumoto, and Kuniyoshi Shimizu. "Antioxidant and Protective Effect of Acetone Extract of Entada phaseoloides Leaves on UVB-Irradiated Human Epidermal Keratinocytes (HaCaT cells) by Inhibiting COX-2, iNOS, and Caspase-3 Activation." Natural Product Communications 17, no. 3 (2022): 1934578X2210786. http://dx.doi.org/10.1177/1934578x221078627.

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Chronic ultraviolet (UV) exposure produces oxidative stress, molecular damage, and aging-related signal transduction, all of which contribute to skin photoaging. In this study, the antioxidant and anti-inflammatory activities of Entada phaseoloides are reported. High-performance liquid chromatography (HPLC) detected 7 phenolic compounds: gallic acid, protocatechuic acid, 4-hydroxybenzoic acid, quercetin, luteolin, kaempferol, and apigenin. We investigated the antioxidant and protective effect of the acetone extract of E. phaseoloides leaves (AEP) on UVB-irradiated human epidermal keratinocytes
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Zhang, Min, Jianhua Zhu, Wei Wang, and Zhiteng Jiang. "Active legumain promotes invasion and migration of neuroblastoma by regulating epithelial-mesenchymal transition." Open Life Sciences 17, no. 1 (2022): 676–85. http://dx.doi.org/10.1515/biol-2022-0012.

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Abstract Neuroblastoma (NB) is a commonly occurring malignancy in children. Epithelial-mesenchymal transition (EMT) is an adaptive change in promoting tumor metastasis. As an important factor in regulating tumor metastasis, whether legumain could promote metastasis of NB by EMT is still unexplored. Legumain is the active form of prolegumain, abundant in tumor plasma. So in the current study, different forms of legumain were identified in NB. Second, correlation analysis of N-cadherin and active legumain was identified by western blot analysis. Third, legumain gene amplification or gene knockdo
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de Jesus Menezes-Filho, Noélio, Cleide dos Santos Souza, Tereza Cristina Silva Costa, et al. "Cytotoxicity of the Diterpene 14-O-Methyl-ryanodanol from Erythroxylum passerinum in an Astrocytic Cells Model." Natural Product Communications 9, no. 9 (2014): 1934578X1400900. http://dx.doi.org/10.1177/1934578x1400900906.

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Plant secondary metabolites, such as, specifically, alkaloids and terpenes, may present psychoactive properties that modify the function of the central nervous system (CNS) and induce neurotoxicity. Neurotoxicity involves the response of glial cells, mainly astrocytes, which play a fundamental role in the control of homeostasis of the CNS. Some Erythroxylum species are indigenous to the state of Bahia in Brazil. This study investigated the cytotoxic activity of the diterpene AEP-1, extracted from the fruit of E. passerinum in a GL-15 cell line, astrocytic, glial cells model. The effects on cel
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Jongjitaree, Suppanut, Sittichai Koontongkaew, Nattisa Niyomtham, Boon-ek Yingyongnarongkul, and Kusumawadee Utispan. "The Oral Wound Healing Potential of Thai Propolis Based on Its Antioxidant Activity and Stimulation of Oral Fibroblast Migration and Proliferation." Evidence-Based Complementary and Alternative Medicine 2022 (May 26, 2022): 1–17. http://dx.doi.org/10.1155/2022/3503164.

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Introduction. Propolis has demonstrated wound healing effects. Propolis’ effects vary based on its composition and geographical origin. However, there are few reports on the effects of propolis on oral wound healing. The aim of this study was to evaluate the antioxidant and in vitro gingival wound healing effects of the n-hexane extract of propolis (HEP), ethyl acetate extract of propolis (EEP), and aqueous extract of propolis (AEP) fractions of the ethanol extract of Thai propolis. Materials and Methods. The crude ethanol extract of propolis was obtained by maceration with 95% ethanol that wa
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McFadden, Dennis, Craig A. Champlin, Michelle H. Pho, Edward G. Pasanen, Mindy M. Maloney, and Erin M. Leshikar. "Auditory evoked potentials: Differences by sex, race, and menstrual cycle and correlations with common psychoacoustical tasks." PLOS ONE 16, no. 5 (2021): e0251363. http://dx.doi.org/10.1371/journal.pone.0251363.

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Auditory brainstem responses (ABRs) and auditory middle-latency responses (AMLRs) to a click stimulus were measured in about 100 subjects. Of interest were the sex differences in those auditory evoked potentials (AEPs), the correlations between the various AEP measures, and the correlations between the AEP measures and measures of otoacoustic emissions (OAEs) and behavioral performance also measured on the same subjects. Also of interest was how the menstrual cycle affected the various AEP measures. Most ABR measures and several AMLR measures exhibited sex differences, and many of the former w
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Bodini, Nicola, and Mike Optis. "Operational-based annual energy production uncertainty: are its components actually uncorrelated?" Wind Energy Science 5, no. 4 (2020): 1435–48. http://dx.doi.org/10.5194/wes-5-1435-2020.

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Abstract. Calculations of annual energy production (AEP) from a wind power plant – whether based on preconstruction or operational data – are critical for wind plant financial transactions. The uncertainty in the AEP calculation is especially important in quantifying risk and is a key factor in determining financing terms. A popular industry practice is to assume that different uncertainty components within an AEP calculation are uncorrelated and can therefore be combined as the sum of their squares. We assess the practical validity of this assumption for operational-based uncertainty by perfo
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Möllerström, Erik, Sean Gregory, and Aromal Sugathan. "Improvement of AEP Predictions with Time for Swedish Wind Farms." Energies 14, no. 12 (2021): 3475. http://dx.doi.org/10.3390/en14123475.

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Based on data from 2083 wind turbines installed in Sweden from 1988 onwards, the accuracy of the predictions of the annual energy production (AEP) from the project planning phases has been compared to the actual wind-index-corrected production. Both the electricity production and the predicted AEP come from Vindstat, a database that collects information directly from wind turbine owners. The mean error for all analyzed wind turbines was 13.0%, which means that, overall, the predicted AEP has been overestimated. There has been an improvement of accuracy with time with an overestimation of 8.2%
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Ghosh, Dipon. "India–ASEAN Economic Relations and North-east India: Act East Policy as a New Paradigm." India Quarterly: A Journal of International Affairs 80, no. 2 (2024): 196–218. http://dx.doi.org/10.1177/09749284241241594.

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The article delves into three aspects: (a) India–ASEAN economic relationship since the last three decades of Look East Policy (LEP), (b) the achievements of North-east India (NEI) under LEP and Act East Policy (AEP) and (c) adding a note on AEP as a new ‘development paradigm’ in NEI. The study finds that the India–ASEAN economic relationship deepened in the post-LEP period as merchandise trade and foreign direct investment (FDI) inflows increased manifold. However, neither LEP nor AEP made any significant impact on NEI in terms of economic growth, exports and FDI inflows. Economic growth stagn
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Živadinović, Biljana, Stefan Todorović, Eva Antić, Mina Stojković, and Milan Janković. "Pathological finding of auditory evoked potentials in patients with vertebral artery hypoplasia associated with posterior circulation stroke." Timocki medicinski glasnik 48, no. 2-3 (2023): 35–38. http://dx.doi.org/10.5937/tmg2302035q.

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The aim of the paper was to determine clinical significance of pathological finding and characteristics of auditory evoked potentials (AEP) in patients with posterior circulation stroke caused by vertebral artery hypoplasia (VAH). The study enrolled 71 patients, 31 of them had posterior circulation stroke. The results of the examinations showed that pathological AEP finding was statistically significantly correlated with posterior circulation stroke (PCS) finding. Changes in AEP amplitude presented a prominent feature of stroke caused by vertebral artery hypoplasia and require further clinical
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Ezekwudo, Daniel E., Rohit Singh, Bolanle Gbadamosi, Mark Micale, Ishmael Jaiyesimi, and Marc Smith. "Prognostic Impact of Bone Marrow Erythropoiesis on Newly Diagnosed Plasma Cell Myeloma: A Single Institutional Analyses." Blood 132, Supplement 1 (2018): 5579. http://dx.doi.org/10.1182/blood-2018-99-116619.

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Abstract Introduction: In plasma cell myeloma (PCM), tumor burden and activity plays an important role in diagnosis and prognosis (e.g. circulating plasma cells), however very little attention has been directed to the impact of the non-plasma cell component of the bone marrow. The presence of anemia has been used to distinguish PCM from smoldering myeloma; however this can be a non-specific finding as there are many potential causes of anemia besides PCM. We sought to determine if the level of erythropoiesis in bone marrow biopsies may be a more reliable prognostic factor. In the study herein,
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Calliess, Iris, Kai Treichel, and Alexis Bowers. "Association of European Psychiatrists (AEP)." International Psychiatry 5, no. 3 (2008): 77. http://dx.doi.org/10.1192/s1749367600002186.

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Sir: Your readers may be interested to know that the Association of European Psychiatrists (AEP) held its 16th Annual Congress in Nice, France, 5-9 April 2008. There were almost 3000 delegates from 57 countries. The theme was ‘Pathways to Integrative Care.’
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Sodiya, E. F., and F. A. Dawodu. "Extracts of leaf as green substitute to zinc compound additives in alkyd primer for corrosion inhibition of mild steel." International Review of Applied Sciences and Engineering, January 13, 2023. http://dx.doi.org/10.1556/1848.2022.00459.

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AbstractApplication of leaf extracts in alkyd extract primer (AEP) to inhibit corrosion of mild steel was compared with performance of alkyd conventional primer (ACP) containing zinc phosphate and zinc chromate as inhibitors. The investigations were carried out through Gasometric technique in 5 °C steps of temperature increase from 25 to 50 °C in 1.0 M HCl as corrodent. The AEP of 34.24 percent actives compared with ACP of 56.57 percent actives gave the same inhibition efficiencies of 76.5%. Extract primer of lower percent active compared with conventional primer were cost effective and more p
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"AEP NEWS." European Psychiatry 16, no. 8 (2001): 510–13. http://dx.doi.org/10.1016/s0924-9338(01)00617-4.

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"AEP News." European Psychiatry 17, no. 6 (2002): 369–70. http://dx.doi.org/10.1016/s0924-9338(02)00702-2.

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"AEP News." European Psychiatry 9, no. 1 (1994): 56–57. http://dx.doi.org/10.1017/s0924933800003229.

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