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Journal articles on the topic 'Alcoholic Liver cirrhosis'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Bell, Helge, Nils Raknerud, Jan A. Falch, and Egil Haug. "Inappropriately low levels of gonadotrophins in amenorrhoeic women with alcoholic and non-alcoholic cirrhosis." European Journal of Endocrinology 132, no. 4 (1995): 444–49. http://dx.doi.org/10.1530/eje.0.1320444.

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Bell H, Raknerud N, Falch JA, Haug E. Inappropriately low levels of gonadotrophins in amenorrhoeic women with alcoholic and non-alcoholic cirrhosis. Eur J Endocrinol 1995;132:444–9. ISSN 0804–4643 We investigated a group of 111 amenorrhoeic females with associated liver disease. These comprised alcoholic cirrhotics (N = 38), non-alcoholic cirrhotics (N = 12), non-cirrhotic alcoholics (N = 21) and those suffering from other chronic liver diseases (N = 40) admitted to our medical department from 1986 to 1991. The serum levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), oe

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Johansson, U., F. Johnsson, B. Joelsson, M. Berglund, and B. Åkesson. "Selenium status in patients with liver cirrhosis and alcoholism." British Journal of Nutrition 55, no. 2 (1986): 227–33. http://dx.doi.org/10.1079/bjn19860029.

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1. Selenium status and blood levels of other nutrients related to lipid peroxidation were studied in patients with advanced alcoholic liver cirrhosis, in male alcoholics who had been abstinent for at least 1 month and in healthy control subjects.2. Plasma Se was decreased in alcoholic cirrhosis but not among alcoholics in abstinence. Platelet glutathione peroxidase (EC 1. 11. 1.9; GSH-Px) activity was decreased in cirrhotic patients, whereas GSH-Px in blood and plasma was the same as in controls for both groups of patients.3. Plasma retinol and plasma α-tocopherol were decreased in alcoholic c

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Prystupa, Andrzej, Paweł Kiciński, Jarosław Sak, Anna Boguszewska-Czubara, Anna Toruń-Jurkowska та Wojciech Załuska. "Proinflammatory Cytokines (IL-1α, IL-6) and Hepatocyte Growth Factor in Patients with Alcoholic Liver Cirrhosis". Gastroenterology Research and Practice 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/532615.

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Background. The aim of the study was to assess the activity of interleukin-1α, interleukin-6, and hepatocyte growth factor protein (HGF) in serum of patients with alcoholic liver cirrhosis.Materials and Methods. Sixty patients with alcoholic liver cirrhosis treated in various hospitals were randomly enrolled. The stage of cirrhosis was assessed according to the Child-Turcotte-Pugh scoring system. The control group consisted of ten healthy persons without liver disease, who did not drink alcohol. Additionally, the group of alcoholics without liver cirrhosis was included in the study. The activi

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Chang, Binxia, Baosen Li, Ying Sun, et al. "Changes in Etiologies of Hospitalized Patients with Liver Cirrhosis in Beijing 302 Hospital from 2002 to 2013." Mediators of Inflammation 2017 (2017): 1–5. http://dx.doi.org/10.1155/2017/5605981.

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Background. Over the last 20 years, the prevalence of hepatitis B virus (HBV) infection in China has decreased gradually due to the application of a national HBV vaccination program. In contrast, the prevalence of alcoholic liver disease (ALD), nonalcoholic fatty liver disease, autoimmune liver disease, and drug-induced liver injury has markedly increased. Methods. We conducted a retrospective review of 82,562 hospitalized patients diagnosed with liver cirrhosis in Beijing 302 Hospital from 2002 to 2013. Results. The top four etiologies of cirrhosis were HBV, HCV, ALD, and autoimmune liver dis

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Zhang, Zhenzhen, Guomin Xie, Li Liang, et al. "RIPK3-Mediated Necroptosis and Neutrophil Infiltration Are Associated with Poor Prognosis in Patients with Alcoholic Cirrhosis." Journal of Immunology Research 2018 (November 25, 2018): 1–7. http://dx.doi.org/10.1155/2018/1509851.

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Alcoholic cirrhosis is an end-stage liver disease with impaired survival and often requires liver transplantation. Recent data suggests that receptor-interacting protein kinase-3- (RIPK3-) mediated necroptosis plays an important role in alcoholic cirrhosis. Additionally, neutrophil infiltration is the most characteristic pathologic hallmark of alcoholic hepatitis. Whether RIPK3 level is correlated with neutrophil infiltration or poor prognosis in alcoholic cirrhotic patients is still unknown. We aimed to determine the correlation of RIPK3 and neutrophil infiltration with the prognosis in the e

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Silveira, Luciano Alves Matias da, Bianca Gonçalves Silva Torquato, Mariana Silva Oliveira, et al. "Implications of alcoholic cirrhosis in atherosclerosis of autopsied patients." Revista da Associação Médica Brasileira 63, no. 4 (2017): 336–40. http://dx.doi.org/10.1590/1806-9282.63.04.336.

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Summary Introduction: Alcoholism is a major public health problem, which has a high social cost and affects many aspects of human activity. Liver disease is one of the first consequences of alcohol abuse, and steatosis, liver cirrhosis and hepatitis may occur. Other organs are also affected with pathological changes, such as pancreatitis, cardiomyopathies, dyslipidemias and atherosclerosis. Objective: To identify the occurrence and degree of atherosclerosis in alcohol-dependent individuals with liver cirrhosis, observing macroscopic and microscopic changes in lipid and collagen deposits and in

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Gaurav R. Waghmare, Vinayak A. Katekar, and Swati P. Deshmukh. "A review: Alcoholic liver disease pathophysiology, current molecular and clinical perspectives." GSC Biological and Pharmaceutical Sciences 25, no. 2 (2023): 014–24. http://dx.doi.org/10.30574/gscbps.2023.25.2.0424.

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Alcohol-related liver damage (ALD) is a term used for a variety of liver conditions comprising cirrhosis, fibrosis, and steatohepatitis with chronic inflammation that is predominantly brought on by heavy alcohol consumption. ALD is currently regarded as one of the most common causes of liver disease-related mortality on a global scale. The majority of cirrhosis in the liver cases seen in district general hospitals in the UK are caused by alcohol, which is a key factor in the Western world. Alcoholic cirrhosis, acute alcoholic hepatitis, and alcoholic fatty liver (steatosis) are the three most

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Gaurav, R. Waghmare, A. Katekar Vinayak, and P. Deshmukh Swati. "A review: Alcoholic liver disease pathophysiology, current molecular and clinical perspectives." GSC Biological and Pharmaceutical Sciences 25, no. 2 (2023): 014–24. https://doi.org/10.5281/zenodo.10579109.

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Alcohol-related liver damage (ALD) is a term used for a variety of liver conditions comprising cirrhosis, fibrosis, and steatohepatitis with chronic inflammation that is predominantly brought on by heavy alcohol consumption. ALD is currently regarded as one of the most common causes of liver disease-related mortality on a global scale. The majority of cirrhosis in the liver cases seen in district general hospitals in the UK are caused by alcohol, which is a key factor in the Western world. Alcoholic cirrhosis, acute alcoholic hepatitis, and alcoholic fatty liver (steatosis) are the three most

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Girleanu, Irina, Anca Trifan, Laura Huiban, et al. "The Risk of Clostridioides difficile Infection in Cirrhotic Patients Receiving Norfloxacin for Secondary Prophylaxis of Spontaneous Bacterial Peritonitis—A Real Life Cohort." Medicina 57, no. 9 (2021): 964. http://dx.doi.org/10.3390/medicina57090964.

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Background and Objectives: Spontaneous bacterial peritonitis (SBP) is a life-threatening complication of liver cirrhosis. Antibiotic prophylaxis is effective but can lead to an increased incidence of Clostridioides difficile infection (CDI). The aim of this study was to evaluate the incidence of CDI and the risk factors in cirrhotic patients with a previous episode of SBP receiving norfloxacin as secondary prophylaxis. Materials and Methods: We performed a prospective, cohort study including patients with liver cirrhosis and SBP, successfully treated over a 2-year period in a tertiary universi

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Anaize Tonon do Amaral, Joice, Renata Salatini, Claudia Arab, et al. "Non-Alcoholic Cirrhosis and Heart Rate Variability: A Systematic Mini-Review." Medicina 56, no. 3 (2020): 116. http://dx.doi.org/10.3390/medicina56030116.

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Background and Objectives: Cirrhosis is a liver disease that causes about one million deaths annually worldwide. The estimated cirrhosis prevalence ranges from 4.5–9.5% in the general population. Up to 40% of cirrhotic patients are asymptomatic and may be diagnosed late. Studies have described the importance of the functions of the liver and autonomic nervous system (ANS) and their relationship. There is limited information available on non-alcoholic cirrhosis and heart rate variability (HRV), which is a measure of the ANS. This study aimed to evaluate cardiac autonomic modulation through HRV

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Shchyokotova, A. P. "Liver cirrhosis." Perm Medical Journal 39, no. 4 (2022): 41–57. http://dx.doi.org/10.17816/pmj39441-57.

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The liver cirrhosis (LC) is a severe disease, the 11th by the cause of death in the world, 50 % of patients die during 5 years. The most frequent etiological factors are alcoholic disease of the liver and chronic viral hepatitis. The following general pathological mechanisms are involved in LC pathogenesis: hepatocyte damage, endothelial dysfunction, oxidant stress, fibrosis activation, pathological regeneration, neoangiogenesis, architectonic impairment of the organ with the development of portal hypertension. Genetic factors contribute to the progression of the liver pathology. Depending on

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Zhang, Kun, Alexander Braun, Francisca von Koeckritz, et al. "Right Heart Remodeling in Patients with End-Stage Alcoholic Liver Cirrhosis: Speckle Tracking Point of View." Journal of Clinical Medicine 8, no. 9 (2019): 1285. http://dx.doi.org/10.3390/jcm8091285.

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Background: Data regarding cardiac remodeling in patients with alcoholic liver cirrhosis are scarce. We sought to investigate right atrial (RA) and right ventricular (RV) structure, function, and mechanics in patients with alcoholic liver cirrhosis. Methods: This retrospective cross-sectional investigation included 67 end-stage cirrhotic patients, who were referred for evaluation for liver transplantation and 36 healthy controls. All participants underwent echocardiographic examination including strain analysis, which was performed offline. Results: RV basal diameter and RV thickness were sign

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Raghava, K. Vijay, H. Shivananda, Darshan Mundinamane, Vinita Boloor, and Biju Thomas. "Evaluation of Periodontal Status in Alcoholic Liver Cirrhosis Patients: A Comparative Study." Journal of Contemporary Dental Practice 14, no. 2 (2013): 179–82. http://dx.doi.org/10.5005/jp-journals-10024-1296.

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ABSTRACT Aim Bacterial infections are common complicating findings in course of liver cirrhosis, most of them being Gram-negative. Similarly periodontal pathogens are also mostly Gram-negative bacteria hence the objective was to evaluate the periodontal status in alcoholic liver cirrhosis patients and to compare the periodontal status of alcoholic liver cirrhosis patients in: a. Smokers with periodontitis and b. Nonsmokers with periodontitis. Materials and methods A total of 150 patients made up the sample of this study. The sample size was divided into four groups. The first two groups compri

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Wani, Ajaz Ahmed, and Younis Rashid. "Epidemiology of Liver Cirrhosis, Associated Complications and its Management: A Review." Saudi Journal of Medical and Pharmaceutical Sciences 10, no. 08 (2024): 603–7. http://dx.doi.org/10.36348/sjmps.2024.v10i08.013.

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Cirrhosis is characterised by the formation of regenerative nodules in liver parenchyma surrounded by fibrous septa due to chronic liver injury. It occurs due to necrosis of liver cells followed by fibrosis and nodule formation. Cirrhosis is the final stage of chronic liver disease and has many causes including viral hepatitis, excessive alcohol intake and non alcoholic steatohepatitis. Liver cirrhosis effects the quality of life and patient survival. Cirrhotic patients are in need of early diagnosis and careful follow up to prevent further complications.This review article covers the clinical

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Lu, Li-Hong, Xue-Ya Lv, Qi-Ming Wu, et al. "Comparison of Electrocardiogram and QT Interval between Viral Hepatitis Cirrhosis and Alcoholic Cirrhosis." Cardiology Research and Practice 2022 (October 18, 2022): 1–4. http://dx.doi.org/10.1155/2022/6934418.

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Objective. This study aims to compare the electrocardiogram (ECG) abnormalities and QT interval prolongation in 2,886 patients with viral hepatitis cirrhosis and 643 patients with alcoholic cirrhosis in order to understand the characteristics of ECG in patients with cirrhosis and provide information and evidence for clinical diagnosis and treatment. Methods. The ECG data of patients with viral hepatitis cirrhosis and alcoholic liver cirrhosis in the outpatients and inpatients of our hospital from August 2012 to July 2018 were reviewed. The ECG data were recorded, and the ECG report was issued

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Sánchez-Rodríguez, A., M. Criado, A. M. Rodríguez-López, A. Esteller, A. Martín De Arriba, and J. M. López-Novoa. "Increased Nitric Oxide Synthesis and Inducible Nitric Oxide Synthase Expression in Patients with Alcoholic and Non-Alcoholic Liver Cirrhosis." Clinical Science 94, no. 6 (1998): 637–43. http://dx.doi.org/10.1042/cs0940637.

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1. The synthesis and release of nitric oxide may play a role in the pathogenesis of peripheral vasodilatation and hyperdynamic circulation observed in liver cirrhosis. In this work, we analysed the synthesis of nitric oxide by the lympho-mononuclear cells of peripheral blood from patients with chronic alcoholic and non-alcoholic liver disease and we identified the isoform of nitric oxide synthase involved in the increased nitric oxide synthesis. 2. Patients were classified following clinical and histological criteria in non-alcoholic cirrhotic, alcoholic cirrhotic and non-cirrhotic chronic liv

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Nikitin, I. G., A. S. Tikhomirova, T. A. Zhinzhilo, et al. "Liver Cirrhosis as the Outcome of Non-Alcoholic Fatty Liver Disease Associated with PNPLA3 Gene RS738409 Polymorphism." Russian Archives of Internal Medicine 10, no. 2 (2020): 148–54. http://dx.doi.org/10.20514/2226-6704-2020-0-2-148-154.

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Relevance: Non-alcoholic fatty liver disease is the most common liver disease worldwide. Although the disease usually has a favorable, asymptomatic course, in some cases it can occur in the form of non-alcoholic steatohepatitis, and some patients may develop cirrhosis of the liver and hepatocellular carcinoma. There are more and more foreign studies proving the relationship of genetic factors with the progression of Non-alcoholic fatty liver disease. However, information about this association in the Russian Federation remains scarce.Goal of the study: to assess the prevalence of patatinlike p

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Nikitin, I. G., A. S. Tikhomirova, T. A. Zhinzhilo, et al. "Liver Cirrhosis as the Outcome of Non-Alcoholic Fatty Liver Disease Associated with PNPLA3 Gene RS738409 Polymorphism." Russian Archives of Internal Medicine 10, no. 2 (2020): 148–54. http://dx.doi.org/10.20514/2226-6704-2020-10-2-148-154.

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Relevance: Non-alcoholic fatty liver disease is the most common liver disease worldwide. Although the disease usually has a favorable, asymptomatic course, in some cases it can occur in the form of non-alcoholic steatohepatitis, and some patients may develop cirrhosis of the liver and hepatocellular carcinoma. There are more and more foreign studies proving the relationship of genetic factors with the progression of Non-alcoholic fatty liver disease. However, information about this association in the Russian Federation remains scarce.Goal of the study: to assess the prevalence of patatinlike p

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R. Sivasubramaniam. "A research study on the utility of GGT level and AST/ALT ratio in alcoholic liver diseases." International Journal of Clinical Biochemistry and Research 11, no. 2 (2024): 85–92. http://dx.doi.org/10.18231/j.ijcbr.2024.015.

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Alcoholic liver disease covers a spectrum of disorders, beginning from the fatty liver, progressing at times to alcoholic hepatitis and culminating in alcoholic cirrhosis, which is the most advanced and irreversible form of liver injury related to the consumption of alcohol. There are three histologic stages of alcoholic liver disease: 1. Alcoholic Fatty Liver or Steatosis: At this stage, fat accumulates in the liver parenchyma. 2. Alcoholic Hepatitis: Inflammation of liver cells takes place at this stage, and the outcome depends on the severity of the damage. Alcohol abstinence, nutritional s

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Dr., Jyoti Umarji, Shobha G. Dr., and Vislavath Srikanth Dr. "Mixed Nodular Liver Cirrhosis A Case Report." International Journal of Trend in Scientific Research and Development 2, no. 5 (2018): 1825–29. https://doi.org/10.31142/ijtsrd18174.

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Cirrhosis of the liver is a diffuse disease, involves entire liver. The prevalence of Cirrhosis increasing globally. Every year approximately 10 lack patients are newly diagnosed in India. The common causes are Chronic Hepatitis C and Alcohol related liver disease. Patients with compensated cirrhosis may present with non specific symptoms or may be asymptomatic. It is associated with the several complications, which have serious effect on health and prognosis of the disease. The end stage of cirrhosis is irreversible and liver transplantation is the only definitive management. This is a case o

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Askgaard, Gro, Janne S. Tolstrup, Mette S. Kjær, and David A. Leon. "Number of hospital contacts with alcohol problems predicts later risk of alcoholic liver cirrhosis." Scandinavian Journal of Public Health 47, no. 4 (2018): 417–19. http://dx.doi.org/10.1177/1403494818763436.

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Aims: Alcoholic liver cirrhosis is usually preceded by years of heavy drinking. We investigated whether the risk of alcoholic liver cirrhosis increases as the number of hospital contacts with alcohol problems goes up. Methods: This was a supplementary analysis on a nationwide register-based cohort study. All patients in Denmark with an initial hospital contact with alcohol problems (alcohol intoxication, harmful alcohol use or alcohol dependence) 1998–2002, free of liver disease, were followed for diagnosis of alcoholic liver cirrhosis. The number of subsequent hospital contacts with alcohol p

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OLIVEIRA, Kalinca S., Luana Reis OLIVEIRA, Sabrina A. FERNANDES, and Gabriela P. CORAL. "MALNUTRITION IN CIRRHOSIS: ASSOCIATION WITH ETIOLOGY AND HEPATOCELLULAR DYSFUNCTION." Arquivos de Gastroenterologia 57, no. 4 (2020): 375–80. http://dx.doi.org/10.1590/s0004-2803.202000000-71.

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ABSTRACT BACKGROUND: The protein-energy malnutrition alters the prognosis of patients with cirrhosis. Its prevalence may vary according to the etiology of liver disease, it´s severity and the evaluation of the method applied. The infection by the hepatitis C virus (HCV) and alcoholism are the main etiologies of cirrhosis and result in a significant morbidity and mortality. OBJECTIVE: To evaluate the nutritional status of patients with cirrhosis according the liver disease etiology and severity. METHODS: It is a prospective study, in which the sample was for convenience and consisted of patient

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Pageaux, G.-P., J. Michel, V. Coste, et al. "Alcoholic cirrhosis is a good indication for liver transplantation, even for cases of recidivism." Gut 45, no. 3 (1999): 421–26. http://dx.doi.org/10.1136/gut.45.3.421.

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BACKGROUND/AIMSAlcoholic cirrhosis remains a controversial indication for liver transplantation, mainly because of ethical considerations related to the shortage of donor livers. The aim of this study was to review experience to date, focusing on survival rates and complications, and the effect of alcohol relapse on outcome and alterations in marital and socioprofessional status.METHODSThe results for 53 patients transplanted for alcoholic cirrhosis between 1989 and 1994 were compared with those for 48 patients transplanted for non-alcoholic liver disease. The following variables were analysed

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Beudeker, Boris J. B., Zwier M. A. Groothuismink, Annemiek A. van der Eijk, Jose D. Debes, and Andre Boonstra. "Circulating Cytokines Reflect the Etiology-Specific Immune Environment in Cirrhosis and HCC." Cancers 14, no. 19 (2022): 4900. http://dx.doi.org/10.3390/cancers14194900.

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Background and Aims: Chronic liver disease—from any etiology—can progress to fibrosis, cirrhosis and hepatocellular carcinoma (HCC). The progression of liver cirrhosis to the end stages of disease is influenced by a variety of factors, including inflammatory cytokines. We pursued a study of cytokine-mediated inflammatory responses in hepatitis B (HBV), hepatitis C (HCV), alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) patients with liver cirrhosis. Methods: Immune profiles were determined through the serum multiplex profiling of >100 cytokines in a 188 cirrhotic

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Menachery, John, and Ajay Duseja. "Treatment of Decompensated Alcoholic Liver Disease." International Journal of Hepatology 2011 (2011): 1–7. http://dx.doi.org/10.4061/2011/219238.

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Alcoholic liver disease (ALD) is a spectrum ranging from simple hepatic steatosis to alcoholic hepatitis and cirrhosis. Patients with severe alcoholic hepatitis can have clinical presentation almost similar to those with decompensated cirrhosis. Scoring with models like Maddrey discriminant function, a model for end-stage liver disease, Glasgow alcoholic hepatitis score, and Lille model are helpful in prognosticating patients with ALD. One of the first therapeutic goals in ALD is to induce alcohol withdrawal with psychotherapy or drugs. Most studies have shown that nutritional therapy improves

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D.Nakhale, Bhaurao. "Study of Autonomic Dysfunction in Alcoholic Cirrhosis of Liver." Journal of Medical Science And clinical Research 05, no. 03 (2017): 18866–74. http://dx.doi.org/10.18535/jmscr/v5i3.93.

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K.C., Geetika. "Diagnosis of Non-alcoholic fatty liver disease." Journal of Pathology of Nepal 6, no. 11 (2016): 947–52. http://dx.doi.org/10.3126/jpn.v6i11.15679.

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Non Alcoholic Fatty Liver Disease is the deposition of fat in liver in absence of excessive of alcohol consumption. Non Alcoholic Fatty Liver Disease ranges from simple steatosis to Nonalcoholic steatohepatitis and cirrhosis. Most cases (90%) of Non Alcoholic Fatty Liver Disease have simple steatosis with benign prognosis. Ten to thirty percent of Non -Alcoholic Fatty Liver Disease progresses to NASH and 25-40% of Nonalcoholic steatohepatitis undergoes progressive liver fibrosis.Ultimately 20-30% of Nonalcoholic steatohepatitis will go into cirrhosis during their lifetime. Nonalcoholic steatoh

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Briggler, Amber, Layla Q. Simmons, and Megan Lane. "The Importance of Sonographic Imaging With Alcoholic Liver Disease: A Case Study." Journal of Diagnostic Medical Sonography 37, no. 1 (2020): 84–90. http://dx.doi.org/10.1177/8756479320944150.

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Alcoholic liver disease (ALD), a precursor to alcohol-induced cirrhosis, is a disease caused by excessive ingestion of alcoholic substances that directly affects liver functions. Abnormal liver function can cause the liver to damage other organs within the abdomen. This case study examines the physiological nature of alcohol-induced cirrhosis and its pathogenesis, external and internal clinical presentations, and treatment options. Treatments for alcohol-induced cirrhosis include liver transplant for permanent correction as well as varied options to manage symptoms. This case study analyzes al

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Rusnak, I. T., N. O. Slyvka, S. O. Akentiev, et al. "CHRONIC PYELONEPHRITIS AS A PRECIPITATING FACTOR OF HEPATORENAL SYNDROME IN PATIENTS WITH ALCOHOLIC LIVER CIRRHOSIS." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 21, no. 3 (2021): 100–103. http://dx.doi.org/10.31718/2077-1096.21.3.100.

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Introduction. Most attempts to assess renal failure in alcoholic liver cirrhosis have so far focused on acute kidney injury and on the hepatorenal syndrome in particular. However, there are still limited data on the prevalence and clinical impact of chronic kidney disease in cirrhosis. Objectives. This study aimed to assess the influence of chronic pyelonephritis on the incidence of hepatorenal syndrome in patients with alcoholic liver cirrhosis. Material and methods. 165 patients with decompensated alcoholic liver cirrhosis and concomitant chronic pyelonephritis were enrolled in the study. Th

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Cao, Xinlu, Oksana Zolnikova, Roman Maslennikov, et al. "Differences in Fecal Short-Chain Fatty Acids between Alcoholic Fatty Liver-Induced Cirrhosis and Non-alcoholic (Metabolic-Associated) Fatty Liver-Induced Cirrhosis." Metabolites 13, no. 7 (2023): 859. http://dx.doi.org/10.3390/metabo13070859.

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The objective of this study was to investigate the metabolic activity of the gut microbiota in cirrhosis due to different variants of fatty liver disease (alcoholic vs. non-alcoholic [metabolic-associated] one [AFLD and MAFLD]). The present study included 24 patients with alcoholic liver cirrhosis, 16 patients with MAFLD-related cirrhosis, and 20 healthy controls. The level and spectrum of short-chain fatty acids (SCFAs) were determined via gas–liquid chromatography. All patients with cirrhosis showed a decrease in the total content of SCFAs (p < 0.001) and absolute content of acetate (p &l

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Platz, K. P., A. R. Mueller, E. Spree, et al. "Liver transplantation for alcoholic cirrhosis." Transplant International 13, S1 (2000): S127—S130. http://dx.doi.org/10.1111/j.1432-2277.2000.tb02000.x.

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Platz, K. P., A. R. Mueller, E. Spree, et al. "Liver transplantation for alcoholic cirrhosis." Transplant International 13, no. 7 (2000): S127—S130. http://dx.doi.org/10.1007/s001470050297.

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Olbrisch, Mary Ellen. "Liver Transplantation for Alcoholic Cirrhosis." JAMA: The Journal of the American Medical Association 261, no. 20 (1989): 2958. http://dx.doi.org/10.1001/jama.1989.03420200048032.

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Olbrisch, M. E. "Liver transplantation for alcoholic cirrhosis." JAMA: The Journal of the American Medical Association 261, no. 20 (1989): 2958b—2958. http://dx.doi.org/10.1001/jama.261.20.2958b.

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Reena, Rani, and Kumar Singh Anupam. "Effect of Alcohol Intake on Liver Function Tests." International Journal of Toxicological and Pharmacological Research 14, no. 1 (2024): 33–35. https://doi.org/10.5281/zenodo.10969558.

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Alcohol consumption has been steadily increasing all over world, especially in India. Alcohol can cause physical, mental and social effects which is determined by quantity and pattern of alcohol drinking. All organs can be damaged due to direct effects of alcohol, especially the digestive and nervous systems. At the level of digestive system, alcohol causes gastrointestinal problems, cirrhosis of liver, pancreatitis and cancer of mouth, pharynx and oesophagus. The present study aims to compare the values of Liver function test, LFT parameters in a group of chronic alcoholics and a matched cont

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Goodall, J. A. D., and C. Bryan. "The Low Incidence of Alcoholic Cirrhosis in the Islands of Lewis and Harris." Scottish Medical Journal 33, no. 2 (1988): 229–30. http://dx.doi.org/10.1177/003693308803300202.

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The annual incidence of clinically apparent cirrhosis of the liver from all causes in the islands of Lewis and Harris has been found to be 5.5 cases per 100,000 and alcoholic cirrhosis to be 2.76 per 100,000. Sales of alcohol in the island amount to £6.85 million giving a per capita spending on alcohol of £283 in 1984. The incidence of alcoholic cardiomyopathy was found to be 3.7 cases per 100,000 and there were 120 admissions per 100,000 with illnesses directly related to alcoholism. It was suggested that the very low incidence of alcoholic cirrhosis despite the high per capita spending on al

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Carbone, Marco, and James Neuberger. "Liver Transplantation for Hepatitis C and Alcoholic Liver Disease." Journal of Transplantation 2010 (2010): 1–8. http://dx.doi.org/10.1155/2010/893893.

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End-stage liver disease due to hepatitis C (HCV) and cirrhosis from alcohol (ALD) are the commonest indications for liver transplantation in the western countries. Up to one third of HCV-infected transplant candidates have a history of significant alcohol intake prior to transplantation. However, there are few data available about the possible interaction between alcohol and HCV in the post-transplant setting. Patients with both HCV and alcohol are more likely to die on the waiting list than those with ALD and HCV alone. However, after transplantation, non-risk adjusted graft and patient survi

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Møller, S., M. Hansen, J. Hillingsø, J.-E. B. Jensen, and J. H. Henriksen. "Elevated carboxy terminal cross linked telopeptide of type I collagen in alcoholic cirrhosis: relation to liver and kidney function and bone metabolism." Gut 44, no. 3 (1999): 417–23. http://dx.doi.org/10.1136/gut.44.3.417.

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BACKGROUNDThe carboxy terminal cross linked telopeptide of type I collagen (ICTP) has been put forward as a marker of bone resorption. Patients with alcoholic liver disease may have osteodystrophy.AIMSTo assess circulating and regional concentrations of ICTP in relation to liver dysfunction, bone metabolism, and fibrosis.METHODSIn 15 patients with alcoholic cirrhosis and 20 controls, hepatic venous, renal venous, and femoral arterial concentrations of ICTP, and bone mass and metabolism were measured.RESULTSCirculating ICTP was higher in patients with cirrhosis than in controls. No overall sign

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Qodirova, Madinabonu Mirzamaxmud qizi. "ANATOMY OF PATHOLOGICAL CHANGES IN THE LIVER UNDER THE INFLUENCE OF ALСOHOL". THEORETICAL ASPECTS IN THE FORMATION OF PEDAGOGICAL SCIENCES 2, № 11 (2023): 44–48. https://doi.org/10.5281/zenodo.7902278.

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This scientific article is about the anatomy of the pathological changes that occur in the liver under the influence of alcohol, and today, as a result of the researches of the specialists of the Health System, the symptoms of serious damage to the liver caused by the consumption of alcohol have been revealed. Specifically, more than 90% of all heavy drinkers develop fatty liver, 25% develop alcoholic hepatitis, and 15% develop cirrhosis. In the early stages, alcoholic fatty liver disease, i.e. fatty liver, later leads to alcoholic hepatitis, and in the final stages, liver cirrhosis.

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Kirchheimer, J. C., K. Huber, P. Polterauer, and B. R. Binder. "Urokinase Antigen in Plasma of Patients with Liver Cirrhosis and Hepatoma." Thrombosis and Haemostasis 54, no. 03 (1985): 617–18. http://dx.doi.org/10.1055/s-0038-1660082.

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SummaryPlasma urokinase antigen levels were studied in 78 patients suffering from liver diseases. Blood was drawn before any specific medication was initiated. Impairment of liver function was comparable in all patients. In both groups of cirrhotic liver disease (alcoholic and non-alcoholic), normal levels of plasma urokinase antigen were found as compared to age-matched control groups. In both groups of patients with hepatomas (with or without a history of liver cirrhosis), however, significantly increased plasma urokinase antigen levels could be determined. These data indicate that an increa

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Romano, D. R., C. Jiménez, F. Rodrı́guez, et al. "Orthotopic liver transplantation in alcoholic liver cirrhosis." Transplantation Proceedings 31, no. 6 (1999): 2491–93. http://dx.doi.org/10.1016/s0041-1345(99)00432-7.

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Enamm S.Abdullah. "Effect of alcohol on liver enzyme (sGOT)." Journal of the College of Basic Education 18, no. 73 (2023): 161–66. http://dx.doi.org/10.35950/cbej.v18i73.9633.

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This study was aimed to estimated effect of alcohol on liver enzyme (GOT) , long term alcohol consumption can cause alcoholic liver disease It leads to develope alcoholic hepatitis and cirrhosis, Most of the liver damage caused by alcohol is attributed to alcohol metabolism and by products of that metabolism, Liver injury may be caused by direct toxicity of alcohol by products and also by inflammation that is induced secondarily by these same compounds, One half of heavy drinkers develop alcoholic hepatitis or cirrhosis

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Zorzano, Antonio, Luis Ruiz del Arbol, and Emilio Herrera. "Effect of liver disorders on ethanol elimination and alcohol and aldehyde dehydrogenase activities in liver and erythrocytes." Clinical Science 76, no. 1 (1989): 51–57. http://dx.doi.org/10.1042/cs0760051.

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1. Liver biopsies were performed in healthy control subjects and in subjects with alcoholic and non-alcoholic liver disease in order to examine alcohol dehydrogenase (ADH; EC 1.1.1.1) and aldehyde dehydrogenase [ALDH; aldehyde dehydrogenase (NAD+); EC 1. 2. 1. 3] activities. Erythrocyte ALDH and ethanol metabolism were also investigated in the same subjects. 2. Fifteen per cent of the subjects studied (seven of 48 subjects tested) presented atypical ADH activity, characterized by elevated activity at pH 7.4 or 8.8 compared with that found in subjects with the usual ADH form. However, the ethan

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Matkovska, N. "Features of the State of Internal Organs and the Structure of Comorbidity in Deceased Persons With Alcoholic Liver Cirrhosis, Non-alcoholic Fatty Liver Disease at the Cirrhosis Stage and Alcoholic Liver Cirrhosis Associated With Insulin Resistance and Obesity." Lviv Clinical Bulletin 2, no. 30 (2020): 35–45. http://dx.doi.org/10.25040/lkv2020.02.035.

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Naga Pradeep, Muvva, and Gonaboyina Deepak Srinivas. "A STUDY OF ECHOCARDIOGRAPHIC CHANGES IN PATIENTS WITH CIRRHOSIS OF LIVER." International Journal of Advanced Research 9, no. 11 (2021): 833–35. http://dx.doi.org/10.21474/ijar01/13810.

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Background/Aims: Cirrhosis is associated with a significant number of cardiac abnormalities but, the information available is scanty about the changes associated with it in India. Which include increased cardiac output, increased wall thickness of cardiac chambers, left ventricular diastolic dysfunction, and PAH. These cardiac abnormalities in patients with Cirrhosis have been termed as Cirrhotic Cardiomyopathy. Cirrhotic Cardiomyopathy may be a significant cause of morbidity and mortality in patients with Cirrhosis. With the advent of increased liver transplantation in India, this entity may

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Fábrega, Emilio, Javier Crespo, Fernando Casafont, Gonzalo De las Heras, J. de la Peña, and Fernando Pons-Romero. "Alcoholic Recidivism After Liver Transplantation for Alcoholic Cirrhosis." Journal of Clinical Gastroenterology 26, no. 3 (1998): 204–6. http://dx.doi.org/10.1097/00004836-199804000-00011.

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Chen, Sheng, Yi-Jie Qiu, Dan Zuo, Shuai-Nan Shi, Wen-Ping Wang, and Yi Dong. "Imaging Features of Hepatocellular Carcinoma in the Non-Cirrhotic Liver with Sonazoid-Enhanced Contrast-Enhanced Ultrasound." Diagnostics 12, no. 10 (2022): 2272. http://dx.doi.org/10.3390/diagnostics12102272.

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Purpose: To investigate the Sonazoid-enhanced contrast-enhanced ultrasound (CEUS) features of hepatocellular carcinoma (HCC) in a non-cirrhosis liver background, in comparison to those in liver cirrhosis. Methods: In this retrospective study, 19 patients with surgery and histopathologically proven HCC lesions in non-cirrhosis liver background were included regarding Sonazoid-enhanced CEUS characteristics. Two radiologists evaluated the CEUS features of HCC lesions according to the WFUMB (World Federation of Societies for Ultrasound in Medicine and Biology) guidelines criteria. Thirty-six patie

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Kjaergaard, Alisa D., Stig E. Bojesen, Børge G. Nordestgaard, and Julia S. Johansen. "YKL-40 and Alcoholic Liver and Pancreas Damage and Disease in 86258 Individuals from the General Population: Cohort and Mendelian Randomization Studies." Clinical Chemistry 60, no. 11 (2014): 1429–40. http://dx.doi.org/10.1373/clinchem.2014.229096.

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Abstract BACKGROUND We tested the hypothesis that observationally and genetically increased YKL-40 concentrations are associated with alcoholic liver and pancreas damage and disease. METHODS We performed cohort and mendelian randomization in 86 258 individuals from the Danish general population, with measured concentrations of plasma YKL-40 (n = 21 646) and CHI3L1 rs4950928 genotype (n = 84 738). RESULTS Increased YKL-40 was associated with increased alanine aminotransferase, bilirubin, alkaline phosphatase, γ-glutamyl transferase, erythrocyte mean corpuscular volume, C-reactive protein, and f

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Galle, P. R., W. J. Hofmann, H. Walczak, et al. "Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage." Journal of Experimental Medicine 182, no. 5 (1995): 1223–30. http://dx.doi.org/10.1084/jem.182.5.1223.

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Apoptosis occurs in the normal liver and in various forms of liver disease. The CD95 (APO-1/Fas) (CD95) receptor mediates apoptosis, and liver cells in animal models are acutely sensitive to apoptosis initiated by this receptor. We have used primary human hepatocytes as a model system to investigate CD95-mediated apoptotic liver damage. Treatment of fresh human hepatocytes with low concentrations of agonistic antibodies against CD95 resulted in apoptosis of &gt; 95% of the cultured liver cells within 4 and 7.5 h. Immunohistology of a panel of explanted liver tissues revealed that hepatocyt

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Calborean, Veronica, Silvia Alina Miscoci, Octavian Istratoaie, et al. "Correlation Between Liver Cirrhosis and Risk of Cardiac Arrhythmias." Revista de Chimie 69, no. 6 (2018): 1527–32. http://dx.doi.org/10.37358/rc.18.6.6361.

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There are few studies analyzing the correlation between liver cirrhosis and cardiac arrhythmias. Still, factors triggering cardiac arrhythmias occur in many instances in liver cirrhosis.We studied a cohort with patientsdiagnosed with liver cirrhosis hospitalized to Cardiology Department, to the County Hospital of Craiova, between January 2017 and January 2018. We wanted to study the frequency of cardiac arrhythmias at the patients diagnosed with liver cirrhosis and also to evaluate several associated factors.The frequency of cardiac arrhythmias in the presence of risk factors was analysed usin

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