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Books on the topic 'Antagonistes AT₁'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

J, Colatsky Thomas, ed. Potassium channels: Basic function and therapeutic aspects : proceedings of the 29th Annual A.N. Richards Symposium held at Valley Forge, Pennsylvania, May 16-17, 1988. Wiley-Liss, 1990.

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2

Matrix Metalloproteinase Conference (1989 Sandestin Beach, Fla.). Matrix metalloproteinases and inhibitors: Proceedings of the Matrix Metalloproteinase Conference held at Sandestin Beach, FL, September 11-15, 1989. Edited by Birkedal-Hansen Henning. G. Fischer Verlag, 1992.

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3

Nekrasov, Stanislav. Social dialectics of prehistory. INFRA-M Academic Publishing LLC., 2021. http://dx.doi.org/10.12737/1078147.

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The author of the monograph, written on the original material, restores the classical scientific social philosophy, which allows the means of dialectical methodology and materialism in sociology to predict the end of the prehistory of antagonistic epochs and the beginning of the true history of a single humanity. The new industrialization at the moment of transition from prehistory to history creates civilizational neo-industrialism as a dialectical synthesis of traditional civilization and progressive formation in the form of new socialism. The global project of neo-industrialism civili

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4

Baldi, Elisabetta, and Corrado Bucherelli. Neuroscience. Firenze University Press, 2017. http://dx.doi.org/10.36253/978-88-6453-638-5.

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This bibliographic material is patrimony of our Laboratory of the Behavior Physiology. This research unit originated in 1972 by will of Aldo Giachetti (until 1990) and with the beginning of the activity of Corrado Bucherelli. In the early 1980s, with Carlo Ambrogi Lorenzini (until 2004), the cataloging became more capillary and systematic, to continue to this day. All the researchers who worked in our laboratory contributed to this collection (Giovanna Tassoni 1986-2000, Benedetto Sacchetti 1996-2002 and Elisabetta Baldi from 1991). The study of learning, memory and behavior requires to follow

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5

Lambert, David G. Mechanisms and determinants of anaesthetic drug action. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0013.

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This chapter is broken into two main sections: a general description of the principles of ligand receptor interaction and a discussion of the main groups of ‘targets’; and explanation of some common pharmacological interactions in anaesthesia, critical care, and pain management. Agonists bind to and activate receptors while antagonists bind to receptors and block the effects of agonists. Antagonists can be competitive (most common) or non-competitive/irreversible. The main classes of drug target are enzymes, carriers, ion channels, and receptors with examples of anaesthetic relevance interacti

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6

Fiorino, Daniel J. Ecology and Economy: Partners or Antagonists? Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190605803.003.0003.

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Ecological policy and politics in the United States and most other countries has turned on the almost inevitable conflicts between ecological and economic goals. US policy recognized this in defining policy as a process of minimizing negatives: of limiting ecological harm while also controlling for pollution and other effects of growth. Instead, policy choices should be built on a green growth strategy—of maximizing the opportunities for positive relationships. This goal is supported by evidence. Ecological policies in the United States have had limited adverse effects on economic growth and c

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7

Y, Wang Rex, and Schoenfeld Ronald, eds. Cholecystokinin antagonists: Proceedings of a workshop held at the Banbury Center of Cold Spring Harbor, New York, September 21-22, 1987. Liss, 1988.

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8

Feng, Alexander J., George C. Chang Chien, and Alan D. Kaye. NMDA Receptor Antagonists, Gabapentinoids, Alpha-2 Agonists, and Dexamethasone. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190457006.003.0002.

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Surgical pain is a major obstacle in the recovery of patients. Effective pain management is of upmost importance to optimize a patient’s recovery, decrease medical complications, and increase patient satisfaction. Traditional pain management with opioids and nonsteroidal anti-inflammatory drugs have significant side effect profiles leading to medical complications or insufficient pain management from reluctance of use. Adjuvant analgesic can provide improved pain management with significantly less side effect profile. In addition, the clinician can, with synergistic effects of adjuvant medicat

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9

Jones, Alison L. Management of opioid poisoning. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0319.

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Opioids are ‘morphine like’ substances that have actions at specific opioid receptors (especially µ receptors) in the central nervous system (CNS). Tolerance of respiratory depression develops at a slower rate than analgesic tolerance, placing patients with a long history of opioid use at particular risk for respiratory depression. If chronic users abruptly stop taking opioids, they develop an acute withdrawal syndrome. Most opioid toxicity is the result of inadvertent overdosage during recreational use or in self-harm, but it can also be due to medication misuse and drug errors. It is charact

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10

Michael, Steinhausen, and World Congress for Microcirculation (4th : 1987 : Tokyo, Japan), eds. Calcium antagonists and microcirculation: Proceedings of a symposium at the Fourth World Congress for Microcirculation, Tokyo/Japan, July 28, 1987. Karger, 1989.

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11

Calcium antagonists: A decade of progress and future prospects, a review based on a symposium held at the Royal Society of Medicine, London, 9-10 July 1986. Medical Education Services, 1987.

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12

Calcium antagonists: A decade of progress and future prospects : a review based on a symposium held at the Royal Society of Medicine, London, 9-10 July 1986. Medical Education Services, 1987.

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13

Paoletti, Rodolfo. Cardiovascular System, Hypertension, and Serotonin Antagonists: Papers Presented at the Intl Symposium on Serotonin : From Cell Biology to Pharmacolo. Kluwer Academic Pub, 1990.

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14

Kasperbauer, T. J. Evolved Attitudes to Animals. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190695811.003.0002.

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This chapter looks at how our attitudes to animals have been shaped by different roles animals played in our evolutionary history. It reviews research on attitudes toward animals across cultures and among very young children. The main argument of the chapter is that we primarily inherited antagonistic attitudes toward animals from our evolutionary forebears. Antagonistic and aversive reactions to animals are discussed within the context of predator–prey relationships and disease avoidance. Positive attitudes to animals are also accounted for by looking at the evolution of pet-keeping and carin

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15

Hildebrand, D. M. Effects of soil solar heating on thermotolerant microorganisms antagonistic to pathogenic Fusarium spp. at Bessey Nursery, Halsey, Nebraska. 1986.

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16

Daum, Andreas W. The Two German States in the International World. Edited by Helmut Walser Smith. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780199237395.013.0032.

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This article centers on the two German states in the 1970s and 1980s. In 1972, however, détente — the period of relaxation, openness, and communication between the two antagonistic superpowers and their allies — had reached its height. Many in the West no longer saw the border that separated the Germans into antagonistic political blocs as an insurmountable ‘Iron Curtain’. The building of the Berlin Wall in August 1961 had been a brutal act. Ironically, its existence opened new opportunities for encounters between West and East. Dialogue, openness, and transparency were values that many in the

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17

Eastman, Brad, and Larry Field. Opioid and Benzodiazepine Overdose. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0092.

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This chapter, “Opioid and Benzodiazepine Overdose,” reviews the pathophysiology of disease state pertaining to overdose as well as the molecular mechanisms involved with drug receptor binding. It discusses common presenting signs and symptoms of opioid and benzodiazepine overdose in the context of a clinical scenario. It also discusses specific patient populations that are at increased risk of opioid and benzodiazepine overdose. Initial and subsequent treatment options are thoroughly examined while allowing the reader to engage in clinical discussions to open-ended questions provided throughou

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18

Nutt, David J., and Liam J. Nestor. The opioid system and addiction. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198797746.003.0010.

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The opioid system of the brain is the major target for opiate drugs such as morphine and heroin, and has been implicated in processes such as pain, stress and reward. Many of these effects take place at the mu opioid receptor (mOR), which is distributed throughout the brain. Significantly, genetic polymorphisms at the mOR may confer a greater dopamine response to the reinforcing effects of alcohol, and it has been suggested that addiction per se may be associated with alterations to the opioid system. There is evidence for the potential efficacy of mOR antagonists (e.g. naltrexone) in reducing

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19

Giersdorf, Jens. Is It OK to Dance on Graves? Edited by Rebekah J. Kowal, Gerald Siegmund, and Randy Martin. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199928187.013.7.

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Catalyzed by Boris Charmatz’s restaging of his 2012–2013 choreography 20 Dancers for the XX Century in June 2014 at the Soviet War Memorial in Berlin, this chapter investigates the complex relationship between modernism and socialist realism in choreography. Concepts like socialism, capitalism, and modernity are not static entities. As discursive models, they rely on other historically determined discourses that accompany them. Modernity and its related concept of modernism require a counterpart against which to be defined. For decades, socialism and socialist realist artistic productions that

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20

Kilkelly, Shannon. Coagulation System. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0090.

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Despite the development of entirely new classes of anticoagulant medication, vitamin K antagonists like warfarin continue to be commonly prescribed for a wide range of cardiovascular diagnoses. Conversely, the advent of low molecular weight heparin has greatly simplified the use of the drug to the point that patients can dose themselves at home with no need for any type of monitoring. Given the widespread use of these medications, it is not surprising that an increasing number of patients requiring urgent or emergent surgery will present with a medically induced coagulopathy. Managing this coa

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21

Iversen, Leslie. The Pharmacology of Delta-9-Tetrahydrocannabinol (THC). Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190846848.003.0002.

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The 19th century was a great era for plant chemistry. Many complex drug molecules, known as alkaloids, were isolated and identified from plants. This chapter discusses the history of the discovery of delta-9-tetrahyrocannabinol (THC) as the psychoactive substance in cannabis products and also the discovery of the cannabinoid receptors CB-1 and CB-2 in the body and brain. The mechanism of action of cannabinoids on such receptors to inhibit neurotransmitter release or other actions is also discussed. In addition, various methods for the ingestion of cannabis, such as smoking and vaping, are revi

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22

Webster, Wendy. The Empire Comes to Britain. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198735762.003.0004.

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This chapter looks at the many people who arrived in Britain from the British Empire—some to serve in the armed forces, others as war workers and wartime propagandists working at the BBC and in British cinema. Mixing between imperial allies produced many close friendships and camaraderie. The British media promoted a vision of an imperial community of allies. But wartime propaganda was potentially undermined by evidence of the practice of colour bars—in the empire and in Britain—and of tensions and antagonisms between imperial allies. Disruption of a publicly disseminated vision of a united em

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23

Tucker, Veta Smith. Secret Agents. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252037900.003.0004.

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This chapter explores the gendered schema at the core of enslaved black women's abolitionist resistance and the scholarly neglect it received by examining the multiple and varied forms of resistance to labor and sexual abuse that four enslaved women engaged in: Mary Elizabeth Bowser, Margaret Garner, Harriet Tubman, and Mary Ellen Pleasant. In all cases, black women manipulated the stereotype of the hapless, deficient, enslaved black woman and used it as camouflage for their anti-slavery and anti-patriarchy insurgency. Either momentarily or permanently, Bowser, Garner, Tubman, and Pleasant bec

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24

Vandenberg, Laura N. Classic Toxicology vs. New Science. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190490911.003.0012.

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Endocrine-disrupting chemicals (EDCs) are compounds that interfere with hormone action. Many EDCs are agonists or antagonists of estrogen, androgen, or thyroid hormone receptors. EDCs are found in many consumer products and are detected at low doses in humans. Using traditional methods from toxicology and risk assessment, these compounds have often been considered benign based on the low exposure levels and few overt signs of toxicity. However, thousands of epidemiology studies have found associations between EDC exposures and disease outcomes, suggesting that the methods used to prioritize ch

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25

Hider, Samantha, and Edward Roddy. Epidemiology of gout. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0038.

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Gout is the most prevalent inflammatory arthritis in men. Data from epidemiological studies conducted in several countries suggest that the prevalence and incidence of gout have risen over the last few decades, although incidence may have stabilized recently. Dietary factors (animal purines, alcohol, and fructose), co-morbid medical conditions (obesity, metabolic syndrome, hypertension, and chronic kidney disease), and medications (diuretics, aspirin, beta blockers, angiotensin converting-enzyme inhibitors, and non-losartan angiotensin II receptor blockers) have been confirmed to be risk facto

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26

Opie, Lionel. Optimal Medical Therapy Post-AMI. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199544769.003.0006.

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• The management of an acute myocardial infarction can be divided into four phases: (a) The initial acute ischaemia causes severe prolonged chest pain when the patient is rushed to a Coronary or Intensive Care Unit; (b) Within the next few hours as ischaemia changes into infarction, the aim at this step is to restore blood flow in the occluded artery by thrombolysis or by percutaneous coronary intervention (PCI); (c) Next, the infarct is established and the left ventricle undergoes early remodeling; (d) Finally, follows the post-AMI post-hospital phase when continued left ventricular remodelin

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27

Zhukovsky, Donna S. Treatment of Opioid-Induced Constipation in Advanced Illness (DRAFT). Edited by Nathan A. Gray and Thomas W. LeBlanc. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190658618.003.0025.

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Opioid-induced constipation is a major problem for patients with advanced medical illness despite aggressive use of bowel regimens. Methylnaltrexone is an opioid antagonist with limited ability to cross the blood–brain barrier and thus is thought to induce opioid withdrawal at the level of the gastrointestinal tract without causing central withdrawal and flare of pain. This chapter describes and evaluates a randomized controlled trial of methylnaltrexone versus placebo and an open label extension study for patients with advanced illness and opioid-induced constipation. Primary outcomes are eff

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28

Erlinge, David, and Göran Olivecrona. Diagnosis and management of non-STEMI coronary syndromes. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0146.

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Acute coronary syndromes are classified as ST segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI) or unstable angina. Most patients with NSTEMI present with a history of chest pain that has subsided spontaneously before or soon after arrival at the emergency room, but with positive cardiac markers (usually troponin T or I) indicative of myocardial infarction. NSTEMI has a risk of recurrent myocardial infarction of 15–20% and a 15% chance of 1-year mortality. Patients with non-STE-acute coronary syndromes are at similar risk as a STEMI patient at 1 year. The strongest objective

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29

Epstein, William M. Conclusion. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190467067.003.0011.

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The Conclusion argues that the nation’s attachment to policy romanticism prevents its social maturation. Incorporating freely chosen, widely cherished values, policy romanticism remains antagonistic to liberal democracy, or at least to the Enlightenment hopes for social progress. Americans are not innocent of American problems. The nation’s problems are created as the effects of consensual, embedded norms. In contrast, the control of social policy making by illegitimate elites is so improbable that mass preference and mass consent would seem to be a logical default position. Mass consent shoul

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30

Finnerup, Nanna Brix, and Troels Staehelin Jensen. Management issues in neuropathic pain. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0133.

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Neuropathic pain is a common complication to cancer, cancer treatment, HIV, and other conditions that may affect the somatosensory nervous system. Neuropathic pain may be present in up to 40% of cancer patients and may persist independently of the cancer and affect the quality of life in disease-free cancer survivors. Particular surgical treatment and chemotherapy may cause chronic persistent neuropathic pain in cancer survivors. The diagnosis of neuropathic pain can be challenging and requires documentation of a nervous system lesion and pain in areas of sensory changes. The pharmacological t

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31

Lichtenstein, Nelson. Writing and Rewriting Labor’s Narrative. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252037856.003.0002.

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This chapter presents the author'a account of how he reframed his understanding of the structures and social impulses that create the consciousness of the working-class as well its antagonists. At Berkeley in the early 1970s he was convinced that neither the law, religion, ethnicity, nor even race were as important as the work experience itself in shaping the consciousness of industrial unionists, whose sit-down strikes and wildcat strikes seemed to emerge directly out of a revolt against hierarchy and authority on the shop floor itself. However, he has come to the conclusion that the relation

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32

Vimalesvaran, Kavitha, and Michael Marber. Myocardial Remodelling after Myocardial Infarction. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0031.

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This chapter focuses on myocardial remodelling, a process that affects the heart’s shape, structure, and function, following myocardial injury (MI). Post-MI remodelling can be divided into three phases, with the first phase 0–72 hours beginning at the time of ischaemic injury, the second phase 72 hours to 6 weeks, and the third and last phase 6 weeks and beyond. During post-infarction remodelling, hypertrophy is an adaptive response that compensates for the increased load, reduces the effect of progressive dilatation, and balances contractile function. The chapter discusses the factors involve

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33

Stavrakakis, Yannis. Populism and Hegemony. Edited by Cristóbal Rovira Kaltwasser, Paul Taggart, Paulina Ochoa Espejo, and Pierre Ostiguy. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780198803560.013.26.

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How can theories of hegemony advance our understanding of populism? Against the background of Gramsci’s work, this chapter draws on Laclau, Mouffe, and other theoretical resources in order to illuminate what shapes and animates populist discourse, what overdetermines its hegemonic potential. We focus on populist articulatory practices as political interventions operating within a broader socio-symbolic as well as psycho-social terrain that both facilitates their formation and—at the same time—limits their scope. The chapter highlights thus the need to take into account the broader terrain of p

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34

Caudill, Edward. The Contrarian and the Commoner. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252038013.003.0003.

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This chapter examines Clarence Darrow and William Jennings Bryan's contrasting worldviews of science and religion. Bryan and Darrow personified two major, antagonistic streams of thought in American society. Bryan believed religion informed all walks of life, including politics and science, whereas Darrow saw it as an impediment to enlightenment. Bryan had unshakable faith in the common man; Darrow called himself a pessimist, apparently with little faith in humanity, but he fiercely defended the rights of the common man. This chapter first discusses Bryan's background as “The Great Commoner,”

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35

Olzer, Rachel, Rebecca L. Ehrlich, Justa L. Heinen-Kay, Jessie Tanner, and Marlene Zuk. Reproductive behavior. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198797500.003.0013.

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Sex and reproduction lie at the heart of studies of insect behavior. We begin by providing a brief overview of insect anatomy and physiology, followed by an introduction to the overarching themes of parental investment, sexual selection, and mating systems. We then take a sequential approach to illustrate the diversity of phenomena and concepts behind insect reproductive behavior from pre-copulatory mate signalling through copulatory sperm transfer, mating positions, and sexual conflict, to post-copulatory sperm competition, and cryptic female choice. We provide an overview of the evolutionary

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36

Scheipers, Sibylle. Clausewitz and the Eighteenth-Century Context of Partisan Warfare. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198799047.003.0002.

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Clausewitz was an ardent analyst of partisan warfare. In 1810 and 1811, he lectured at the Berlin Kriegsschule, the war academy, on the subject of small wars. Clausewitz’s lectures focused on the tactical nature of small wars. However, the eighteenth-century context was by no means irrelevant for Clausewitz’s further intellectual development. On the contrary, he extrapolated from his analysis of the tactical nature of small wars their strategic potential, as well as their exemplary nature for the study of war as such. The partisan, in Clausewitz’s eyes, possessed exemplary qualities in that he

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37

Goldberg, Brian. Poetry and Social Class. Edited by David Duff. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780199660896.013.11.

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During the Romantic period, poetry and social class were intimately connected. Many of the period’s political arguments were about the social hierarchy, and poetic writing often reflected these debates. A poet’s social origin also had much to do with what he or she wrote and how that writing might be received. Fundamentally, audiences assumed that a legitimate poet would have a classical education unavailable to writers below a certain rank. Poets regularly attempted to challenge perceived class distinctions, sometimes by experimenting with the voices and viewpoints of other ranks, sometimes b

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38

Carr, James Revell. Hukihuki. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252038600.003.0004.

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This chapter deals with the antagonistic relationship between American missionaries and American sailors, in which Hawaiians were caught in the middle. It shows how that conflict literally played out on theatrical and musical stages in Hawaii and on the mainland. It frames this struggle using the indigenous Hawaiian term hukihuki, which means “the constant, opposing emotional pull two or more persons in conflict may exert on a third person, ostensibly to win his love, loyalty or influence but actually to gain supremacy in the two way power struggle.” Missionaries sought to keep Hawaiians attac

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39

Kanduč, M., A. Schlaich, E. Schneck, and R. R. Netz. Interactions between biological membranes: theoretical concepts. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198789352.003.0012.

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In this chapter we review the various types of generic (non-specific) forces acting between lipid membranes in an aqueous environment and discuss the underlying mechanisms, with particular focus on the competing roles of enthalpic and entropic contributions. The interaction free energy (or interaction potential) is typically the result of a subtle interplay of several, often antagonistic contributions with comparable magnitude. First, we will briefly introduce the underlying physics of various kinds of surface–surface interactions, starting with theories of van der Waals and undulation interac

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40

Masters, Ben. Introduction. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198766148.003.0001.

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The introduction shows how a general suspicion of stylistic flamboyance in post-war England led writers like Anthony Burgess, Angela Carter, and Martin Amis to feel at odds with English literary culture. Reconsidering these writers as sophisticated stylists and ethicists—the ‘stylists of excess’—the introduction outlines the major arguments of the ethical turn in literary criticism, describing some of the general antagonisms between the humanist revival and the new ethics, before suggesting a literary ethics that borrows from both without over-relying on notions of character and interiority (c

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41

Wheeldon, Marianne. The Controversy over the Ode à la France. Oxford University Press, 2018. http://dx.doi.org/10.1093/acprof:oso/9780190631222.003.0004.

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Chapter 4 considers the posthumous premieres of 1928 and their performance in a high-profile concert commemorating the tenth anniversary of the composer’s death. The event sparked fevered debate in the press and occasioned a surge of vitriolic commentary. By performing unpublished works from Debussy’s student years as well as his final incomplete work, the Ode à la France, the concert program and ensuing controversy got to the heart of what was now at stake in the composer’s posthumous reputation: what should be commemorated and who had the authority to decide. The struggle over these two ques

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42

Mellman, Thomas A. Sleep and PTSD. Edited by Charles B. Nemeroff and Charles R. Marmar. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190259440.003.0023.

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The Chapter reviews two long standing concerns of sleep research in PTSD. The first is characterizing dysregulations of arousal that manifest in relation to sleep including disturbances of sleep initiation, maintenance, and depth. The other is characterizing nightmare disturbances in PTSD and establishing the role of the neurophysiological substrate of dreams, rapid eye movement sleep (REMS), in the disorder. While there has been uncertainty and controversy regarding these issues, a comprehensive look at findings and their context (e.g. duration of PTSD, setting of recordings) allows some reco

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43

Fudin, Jeffrey, Jacqueline Cleary, Courtney Kominek, Abigail Brooks, and Thien C. Pham. Screening Patients for Opioid Risk (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190265366.003.0010.

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The narrow therapeutic index associated with most analgesic opioids creates a high degree of risk, obliging caution in patient selection; this chapter describes screening practices. More attention is due to the use of opioid therapy for chronic non-cancer pain as episodes of respiratory arrest increase. Universal precautions are recommended for all patients. Before and throughout treatment, selected tools assessing risk and misuse should be employed. Increased access to the opioid antagonist naloxone has followed the increase in opioid poisoning deaths; the Risk Index for Overdose or Serious O

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44

Alhazzani, Waleed, and Deborah J. Cook. Stress ulcer prophylaxis and treatment drugs in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0041.

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Many changes have occurred over the last three decades in the field of stress ulcer gastrointestinal bleeding and its prevention. The topic is controversial, fuelled by disparate data, studies at risk of bias, and the impression that the problem is not as serious as it once was. Indeed, compared with over four decades ago when mucosal ulceration of the stomach causing serious bleeding was first described, a relatively small proportion of critically-ill patients now develop clinically important bleeding. Acid suppression is commonly prescribed for stress ulcer prophylaxis (SUP), targeting subgr

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45

Koczanowicz, Leszek. Politics of Dialogue. Edinburgh University Press, 2015. http://dx.doi.org/10.3366/edinburgh/9780748644056.001.0001.

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Contemporary democracy is in crisis. People are losing faith in in a system of democratic institutions that can cope with current social problems. The book sheds new light on this issue, drawing on the ideas of M. M. Bakhtin, American pragmatism, and others to show that dialogue in democracy can transcend both antagonistic and consensual perspectives. The author provides an overview of the history of the dialogue-vs.-antagonism opposition as it is embedded in modern political theory, and outlines the concept of dialogue in contemporary political thought. The author argues that dialogue is a va

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Newcomb, John Timberman. Poetry’s Opening Door. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252036798.003.0003.

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This chapter examines how the New Verse movement achieved spectacular success by focusing on the role played by Poetry: A Magazine of Verse, particularly in creating a space for contemporary American verse where none had been. Poetry, founded by Harriet Monroe in Chicago in 1912, exemplifies the productive intersection between twentieth-century artistic avant-gardes and the forces of modern disciplinary specialization. This chapter looks at how Monroe and others forged Poetry's identity through antagonistic opposition to such “standpatters” as the “quality magazines,” transforming it into a pi

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R, Rolland, Chadha Dev R, and Willemsen, Wilhelmus Nicolass Petrus, 1947-, eds. Gonadotropin down-regulation in gynecological practice: Proceedings of an international symposium held at the University of Nijmegen, the Netherlands, April 25 and 26, 1986. Liss, 1986.

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Aston, Nigel, and Benjamin Bankurst, eds. Negotiating Toleration. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198804222.001.0001.

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The year 1714 was a revolutionary one for Dissenters across the British Empire. The Hanoverian Succession upended a political and religious order antagonistic to Protestant non-conformity and replaced it with a regime that was, ostensibly, sympathetic to the Whig interest. The death of Queen Anne and the dawn of Hanoverian Rule presented Dissenters with fresh opportunities and new challenges as they worked to negotiate and legitimize afresh their place in the polity. The essays in this collection examine how Dissenters and their allies in a range of geographic contexts confronted and adapted t

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Sharma, Mukul. Conclusion. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199477562.003.0006.

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In the conclusion the author summarizes his arguments and research findings, bringing in discussions on some of the initiatives taken by the Dalits and other organizations to link up the issues of caste, nature, and Dalit movements. He points towards the new generation of environmental questions, especially in the context of caste, Dalits, identity, ethnicity, minority, democracy, and development. Dalit–Brahmin encounters in the realm of nature have been antagonistic, but there could be some internal commonalities dissolving the differences and complementing each other at complex levels. He co

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Stevens, Philip, and Paul Dark. Ileus and obstruction in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0182.

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Obstruction is the commonest cause of acute intestinal failure in critical care. Management is dependent upon whether it is adynamic or mechanical in origin. Paralytic ileus is managed conservatively by correction of electrolyte disturbances, nutritional support, and minimization of enterostatic drug use. Pharmacological agents aimed at reducing sympathetic stimuli may be useful, although widespread application is limited due to anti-muscarinic side effects. Peripherally acting μ‎-opioid receptor antagonists, may have a role, although data in critical illness are lacking. Prokinetic agents hav

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