Academic literature on the topic 'Anti-Convulsion Drugs'

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Journal articles on the topic "Anti-Convulsion Drugs"

1

Sadgunottama goud kamparaj, Kudagi B L, Karikal H P, Muthiah N S, and Pravin Kumar R. "Evaluation of the anticonvulsant activity of the phosphodiesterase III inhibitor cilostazol in the animal model of epilepsy." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (2020): 3391–95. http://dx.doi.org/10.26452/ijrps.v11i3.2476.

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The present study is objected to evaluate the anticonvulsant activity of the phosphodiesterase III inhibitor cilostazol in the animal model of epilepsy. Conventional anti-epileptic rodent models like Maximal Electric Shock (MES)- induced convulsions and Pentylenetetrazol (PTZ) induced convulsions were used. The animals were randomly divided into six groups, with six rats in every group. Here anti-epileptic activity of cilostazol with two different doses (10 mg/kg i.p and 20 mg/kg i.p) was compared with standard drug and standard drug + Cilostazol two different doses (10 mg/kg i.p and 20 mg/kg
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2

Tanaka, Kazuhiko, Masakatsu Nozaki, Takashi Nose, Kimio Yasuda, Kaito Tsurumi, and Hajine Fujimura. "Convulsion induced by combination with new quinolone antimicrobials and anti-inflammatory drugs." Japanese Journal of Pharmacology 46 (1988): 240. http://dx.doi.org/10.1016/s0021-5198(19)57560-6.

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3

Saad, Shaban E. A., Suhera M. Aburawi, Ahlaam A. Rahoumh, Ahlaam A. Rahoumh та Akram Abdraheem. "Influence of β- blockers on the activity of some anti-epileptic drugs on convulsions induced by picrotoxin in mice". Libyan Journal of Medical Research 16, № 2 (2022): 127–34. http://dx.doi.org/10.54361/ljmr.16210.

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Adrenergic β-receptor blockers are widely used in clinic for the management of cardiovascular disease and some other illnesses. However, this group of drugs known to cause central nervous system side effects such as drowsiness, sleep disturbance, hallucination, migraine and tremors. As anti-epileptic drugs exert their action mainly through the inhibition of the central nervous system to decrease the firing and the excitability of neurons. Accordingly, β-blockers might influence the pharmacological activity of anti-epileptic drugs. Aim:The aims of this study is to investigate the influence of β
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4

C., Muralidhar, Vijay Prasad S., and Sridhar I. "Anticonvulsant effect of nifedipine, dizepam and in combination on pentylenetetrazol induced experimental models of epilepsy on albino rats." International Journal of Basic & Clinical Pharmacology 6, no. 11 (2017): 2577. http://dx.doi.org/10.18203/2319-2003.ijbcp20174634.

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Background: In many patients, the presently available antiepileptic drugs such as phenobarbital, phenytoin, benzodiazepines, sodium valproate, etc., are unable to control seizures efficiently and the problem of adverse effects has also not been circumvented completely and approximately 30% of the patients continue to have seizures with current antiepileptic drugs therapy. Hence, search should continue to develop newer, more effective, and safer neuro-protective agents for treatment of epilepsy. Aim of the study was to investigate the activity of nifedipine, the dihydropyridine calcium channel
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5

Zaib-un-nissa*, Muhammad Iqbal Suhail Ahmed Almani Aatir H. Rajput Muhammad Muneeb Hamid Memon Syed Jehangir and Shahrukh Shaikh. "CASUAL COMPARATIVE ANALYSIS OF GINGIVAL INDEX SCORE AMONG EPILEPTIC PATIENTS USING CARBAMAZEPINE, SODIUM VALPROATE AND PHENYTOIN." Indo American Journal of Pharmaceutical Sciences 04, no. 06 (2017): 1565–69. https://doi.org/10.5281/zenodo.817621.

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Abstract: Objective: This research hoped to compare the periodontal health of epileptic patients using three different anti-epilepsy drugs, namely, carbamazepine, phenytoin and sodium valproateusing the gingival index score. Methodology: This casual comparative analysis of periodontal health was conducted at Liaquat University Hospital from January to March (2017) upon 3 groups of patients, each using a different anti-epileptic drug. The groups comprised of 15 patients each and the groups were matched for age, sex and duration of drug therapy. All recordings made on the gingival index score on
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6

Sikarwar, Saurav Singh, Kratika Daniel, and Neetesh Kumar Jain. "Synthesis, Characterization and Anti-Convulsant Activity of Novel Substituted Oxadiazole Derivatives." International Journal of Medical Sciences and Pharma Research 8, no. 2 (2022): 55–59. http://dx.doi.org/10.22270/ijmspr.v8i2.39.

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Seizures are sudden, transitory, and uncontrolled episodes of brain dysfunction resulting from abnormal discharge of neuronal cells with associated motor, sensory or behavioral changes. Anticonvulsants (also commonly known as antiepileptic drugs or as ant seizure drugs) are a diverse group of pharmaceuticals used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of bipolar disorder, since many seem to act as mood stabilizers, and for the treatment of neuropathic pain. Anticonvulsants suppress the rapid and excessive firing of neurons duri
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7

Vishal N Kushare and Saravanan S. "Invitro and invivo evaluation of anticonvulsant herbal drug loaded self nano emulsifying drug delivery system." International Journal of Pharmaceutical Research and Life Sciences 6, no. 2 (2018): 38–44. http://dx.doi.org/10.26452/ijprls.v6i2.1279.

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The aim of present study was to formulate and evaluate emulsifying drug delivery system (SNEDDS) of poorly and herbal drug like () extract, which was extracted from Coriandrum seeds by using ( method extraction process). are isolated by using column chromatography and concentrated under reduced pressure by using rotary flash evaporator., an essential of Coriandrum with anti-epileptic activity.the oil phase like , Tween 80 and PEG-200 were selected as and respectively for the formulation of SNEDDS(9 formulation). all the formulation S9 shows maximum cumulative amount of drug release of about97.
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8

Kathuria, Ishita, and Bhupesh Singla. "Anti-tumor efficacy of Calculus bovis: Suppressing liver cancer by targeting tumor-associated macrophages." World Journal of Gastroenterology 30, no. 38 (2024): 4249–53. http://dx.doi.org/10.3748/wjg.v30.i38.4249.

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Despite significant advances in our understanding of the molecular pathogenesis of liver cancer and the availability of novel pharmacotherapies, liver cancer remains the fourth leading cause of cancer-related mortality worldwide. Tumor relapse, resistance to current anti-cancer drugs, metastasis, and organ toxicity are the major challenges that prevent considerable improvements in patient survival and quality of life. Calculus bovis (CB), an ancient Chinese medicinal drug, has been used to treat various pathologies, including stroke, convulsion, epilepsy, pain, and cancer. In this editorial, w
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9

Xie, Xingcheng, Han Guo, Juan Liu, Junbao Wang, Huihui Li, and Zhongyuan Deng. "Edible and Medicinal Progress of Cryptotympana atrata (Fabricius) in China." Nutrients 15, no. 19 (2023): 4266. http://dx.doi.org/10.3390/nu15194266.

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As an important resource insect, the Cryptotympana atrata is widely distributed in the eastern and central parts of China. The cicada slough is one of the traditional crude drugs in East Asia, and the main component is polysaccharide, which has the functions of anti-convulsion, relieving asthma and improving lipid metabolism. The parasitoid fungus Cordyceps cicadae, which grows inside the cicada nymphs and forms the fruiting bodies on the surface of the host’s carcass, is also known as the “cicada flower” in China. The Cordyceps cicadae is another old, traditional Chinese medicine, which has b
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10

Preethi, Preethi, G. Sumathy, and Venkatalakshmi Venkatalakshmi. "Nardostachys Jatamansi DC: A Medicinal Treasure in Peril(A Review)." Journal of Neonatal Surgery 14, no. 9S (2025): 250–59. https://doi.org/10.52783/jns.v14.2653.

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The miraculous but endangered plant, Nardostachys Jatamansi DC is a highly medicinal value, primitive, and therapeutic herbal plant used in both daily self-care and professionally managed health care. It is an endangered species due to overexploitation of its rhizomes for medicinal, aromatic uses, folk medicine, overgrazing, loss of habitats, and forest degradation. All the parts of the plants are used for various therapeutic activities like Alzheimer’s, anti-convulsion, antioxidants, hair growth, hepatoprotective, Parkinson’s, etc. Phytosterols, terpenoids, flavonoids, and phenolic compounds
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