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Relevant bibliographies by topics / Antiviral drug

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Academic literature on the topic 'Antiviral drug'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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Journal articles on the topic "Antiviral drug"

1

Anasir, Mohd Ishtiaq, Babu Ramanathan, and Chit Laa Poh. "Structure-Based Design of Antivirals against Envelope Glycoprotein of Dengue Virus." Viruses 12, no. 4 (2020): 367. http://dx.doi.org/10.3390/v12040367.

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Dengue virus (DENV) presents a significant threat to global public health with more than 500,000 hospitalizations and 25,000 deaths annually. Currently, there is no clinically approved antiviral drug to treat DENV infection. The envelope (E) glycoprotein of DENV is a promising target for drug discovery as the E protein is important for viral attachment and fusion. Understanding the structure and function of DENV E protein has led to the exploration of structure-based drug discovery of antiviral compounds and peptides against DENV infections. This review summarizes the structural information of

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Coen, Donald M., and Richard J. Whitley. "Antiviral drugs and antiviral drug resistance." Current Opinion in Virology 1, no. 6 (2011): 545–47. http://dx.doi.org/10.1016/j.coviro.2011.10.024.

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Hajjo, Rima, Dima A. Sabbah, Osama H. Abusara, Reham Kharmah, and Sanaa Bardaweel. "Targeting Human Proteins for Antiviral Drug Discovery and Repurposing Efforts: A Focus on Protein Kinases." Viruses 15, no. 2 (2023): 568. http://dx.doi.org/10.3390/v15020568.

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Despite the great technological and medical advances in fighting viral diseases, new therapies for most of them are still lacking, and existing antivirals suffer from major limitations regarding drug resistance and a limited spectrum of activity. In fact, most approved antivirals are directly acting antiviral (DAA) drugs, which interfere with viral proteins and confer great selectivity towards their viral targets but suffer from resistance and limited spectrum. Nowadays, host-targeted antivirals (HTAs) are on the rise, in the drug discovery and development pipelines, in academia and in the pha

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Žigrayová, Dominika, Veronika Mikušová, and Peter Mikuš. "Advances in Antiviral Delivery Systems and Chitosan-Based Polymeric and Nanoparticulate Antivirals and Antiviral Carriers." Viruses 15, no. 3 (2023): 647. http://dx.doi.org/10.3390/v15030647.

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Current antiviral therapy research is focused on developing dosage forms that enable highly effective drug delivery, providing a selective effect in the organism, lower risk of adverse effects, a lower dose of active pharmaceutical ingredients, and minimal toxicity. In this article, antiviral drugs and the mechanisms of their action are summarized at the beginning as a prerequisite background to develop relevant drug delivery/carrier systems for them, classified and briefly discussed subsequently. Many of the recent studies aim at different types of synthetic, semisynthetic, and natural polyme

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Komarasamy, Thamil Vaani, Nur Amelia Azreen Adnan, William James, and Vinod RMT Balasubramaniam. "Finding a chink in the armor: Update, limitations, and challenges toward successful antivirals against flaviviruses." PLOS Neglected Tropical Diseases 16, no. 4 (2022): e0010291. http://dx.doi.org/10.1371/journal.pntd.0010291.

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Flaviviruses have caused large epidemics and ongoing outbreaks for centuries. They are now distributed in every continent infecting up to millions of people annually and may emerge to cause future epidemics. Some of the viruses from this group cause severe illnesses ranging from hemorrhagic to neurological manifestations. Despite decades of research, there are currently no approved antiviral drugs against flaviviruses, urging for new strategies and antiviral targets. In recent years, integrated omics data-based drug repurposing paired with novel drug validation methodologies and appropriate an

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Abdulsamed, Mohamed, Ashraf A Naass, Mohamed S. A. Eswani, Mohamed O Elbasir, and Sedigh Bashir. "Advancing Precision Drug Therapy in Pregnant Women: PBPK Modeling of Antiviral Drugs." Translational Medicine: Open Access 2, no. 2 (2024): 01–17. https://doi.org/10.33140/tmoa.02.02.01.

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PBPK/PD modeling is essential in modern drug development. Traditional drug development methods frequently rely on trial and error, which can be time-consuming, costly, and could be risky. Predicting pharmacokinetics (PK) of drugs in pregnant women, encompassing the intricate aspect of placental drug transfer, remains a complex task. This study was to compare of simulated or predicted and observed (previously published approaches) pharmacokinetic parameters among the four antiviral drugs in pregnant and non-pregnant women. In addition, this investigation endeavors to construct and assess physio

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Plummer, Emily, Michael D. Buck, Marisa Sanchez, et al. "Dengue Virus Evolution under a Host-Targeted Antiviral." Journal of Virology 89, no. 10 (2015): 5592–601. http://dx.doi.org/10.1128/jvi.00028-15.

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ABSTRACTThe host-targeted antiviral drug UV-4B reduces viral replication and promotes survival in a mouse model of experimental dengue virus (DENV) infection. UV-4B is an iminosugar that inhibits the α-glucosidase family of enzymes and subsequently the folding of glycosylated proteins, both viral and host. Here, we utilized next-generation sequencing to investigate evolution of a flavivirus under selective pressure by a host-targeted antiviralin vivo. In viral populations recovered from UV-4B-treated mice, there was a significant increase in the number of single-nucleotide polymorphisms (SNPs)

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Oksenych, Valentyn, and Denis E. Kainov. "Broad-Spectrum Antivirals and Antiviral Drug Combinations." Viruses 14, no. 2 (2022): 301. http://dx.doi.org/10.3390/v14020301.

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Taburet, Anne-Marie, and Eric Singlas. "Drug Interactions with Antiviral Drugs." Clinical Pharmacokinetics 30, no. 5 (1996): 385–401. http://dx.doi.org/10.2165/00003088-199630050-00005.

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Becker, Y. "Transfer of antivirals to skin Langerhans cells--a novel approach to anti-HIV treatment by "antiviral peplotion"." Acta Biochimica Polonica 43, no. 1 (1996): 175–81. http://dx.doi.org/10.18388/abp.1996_4575.

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The analysis of the history of the research on antivirals especially the treatment of HIV-1 infected individuals with antivirals which were developed prior to the current AIDS epidemic led to suggest a different approach to the targeting of antivirals in the AIDS patients. Since HIV-1 replication in infected individuals occurs in the lymph nodes, it is suggested that modified anti-HIV-1 drugs should be applied to Langerhans cells in the skin. The Langerhans cells can serve as the carries of the antiviral drugs attached to their surfaces due to their ability to migrate from the skin through the

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Dissertations / Theses on the topic "Antiviral drug"

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Clifton, Heather A. "Computational antiviral drug design." Muncie, Ind. : Ball State University, 2009. http://cardinalscholar.bsu.edu/645.

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Klimenko, Kyrylo. "Computer-aided drug design of broad-spectrum antiviral compounds." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAF008/document.

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De nouveaux antiviraux à large spectre, agissant comme intercalant d'acides nucléiques, ont été identifiés par criblage virtuel et grâce à des cartes de l’espace chimique. La 1ère partie de la thèse présente le modèle QSPR pour la solubilité aqueuse des molécules organiques dans une grande gamme de températures. Ce modèle a été utilisé pour l'évaluation de la solubilité des composés antiviraux. Dans la 2ème partie de cette thèse, les filtres structuraux, les modèles QSAR et pharmacophores sont présentés. Leur utilisation pour cribler une base de données contenant plus de 3,2 M de composés est

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Junaid, Muhammad. "Studies of Retroviral Reverse Transcriptase and Flaviviral Protease Enzymes as Antiviral Drug Targets : Applications in Antiviral Drug Discovery & Therapy." Doctoral thesis, Uppsala universitet, Institutionen för farmaceutisk biovetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-173504.

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Viruses are a major threat to humans due to their unique adaptability, evolvability and capability to control their hosts as parasites and genetic elements. HIV/AIDS is the third largest cause of death by infectious diseases in the world, and drug resistance due to the viral mutations is still the leading cause of treatment failure. The flaviviruses, such as Dengue virus (DEN) and Japanese encephalitis virus (JEV), represent other major cause of morbidity and mortality, and the areas where these viruses are endemic are spreading rapidly. No curative therapy for any flavivirus could be made av

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Sun, Jian. "Computer-aided drug design for influenza A virus." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B44205156.

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Martin, Baptiste. "Méthyltransférases des filovirus et autres mononégavirus : caractérisation, originalités et drug design." Thesis, Aix-Marseille, 2017. http://www.theses.fr/2017AIXM0258.

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Les virus appartenant à l’ordre des Mononegavirales possèdent une « large » protéine L, responsable du cycle réplication/transcription et de maturation des ARNs. Six domaines conservés portent les différentes activités de cette protéine dont le site catalytique d’une activité méthyltransférase (MTase) de la coiffe. La coiffe est une structure chimique constituée d’une guanosine méthylée en position N7 reliée à l’extrémité 5’ des ARNm par une liaison 5’-5’ triphosphate. Une seconde méthylation est également présente en position 2’O du ribose du premier nucléotide de l’extrémité 5’ de l’ARNm. Ce

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Aldhumani, Ali Hamed. "Pharmacophore Model Development: Targeting Noncoding RNA for Antibacterial/Antiviral Drug Discovery." Ohio University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1610705872573225.

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Loughlin, Anita Marie. "Access to antiviral medication for HIV and HCV infected drug users." Available to US Hopkins community, 2003. http://wwwlib.umi.com/dissertations/dlnow/3080718.

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Dragoni, Filippo. "Antiviral drug development for treatment of acute and chronic viral infections." Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1127988.

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Background Viruses are aetiologic agents of several human infectious diseases, which can be distinguished into acute and chronic. Among the agents causing acute infections, arboviruses, such as Dengue (DENV), West Nile (WNV) and Zika (ZIKV) Viruses, have increasingly spread worldwide. Moreover, the newly discovered Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), causing the COVID-19 disease, is responsible for an incredibly quantity of infections and deaths. Conversely, the Human Immunodeficiency Virus (HIV-1) is a well-known pathogen able to cause chronic latent infection, but

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Benson, T. J. "The attempted synthesis of some novel imidazoyl and pyrrolyl n-nucleosides with potential antiviral activity." Thesis, University of Manchester, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.237245.

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Sun, Jian, and 孙健. "Computer-aided drug design for influenza A virus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B44205156.

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Books on the topic "Antiviral drug"

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De Clercq, Erik, and Richard T. Walker, eds. Antiviral Drug Development. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-7275-2.

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De Clercq, Erik, ed. Antiviral Drug Strategies. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635955.

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Clercq, Erik De. Antiviral drug strategies. Wiley-VCH, 2011.

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D, Richman Douglas, ed. Antiviral drug resistance. Wiley, 1996.

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L, LaFemina Robert, and American Society for Microbiology, eds. Antiviral research: Strategies in antiviral drug discovery. ASM Press, 2009.

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Liu, Xinyong, Peng Zhan, Luis Menéndez-Arias, and Vasanthanathan Poongavanam, eds. Antiviral Drug Discovery and Development. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-0267-2.

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Challand, Richard. Antiviral chemotherapy. Spektrum, 1997.

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NATO, Advanced Study Institute on Antiviral Drug Development: a. Multidisciplinary Approach (1987 Lucca Italy). Antiviral drug development: A multidisciplinary approach. Plenum Press, 1988.

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E, Blair, ed. Antiviral therapy. BIOS Scientific Publishers, 1998.

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Hofmann, F. Antiviral Strategies. Springer Berlin Heidelberg, 2009.

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Book chapters on the topic "Antiviral drug"

1

Rhee, Douglas J., Kathryn A. Colby, Lucia Sobrin, and Christopher J. Rapuano. "Antiviral Agents." In Ophthalmologic Drug Guide. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-7621-5_3.

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Meanwell, Nicholas A., Stanley V. D'Andrea, Christopher W. Cianci, et al. "Antiviral Drug Discovery." In Drug Discovery. John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118354483.ch11.

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Field, Hugh J., and Lindsey J. Owen. "Virus Drug Resistance." In Antiviral Drug Development. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-7275-2_12.

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De Clercq, Erik. "Outlook of the Antiviral Drug Era, Now More Than 50 Years after Description of the First Antiviral Drug." In Antiviral Drug Strategies. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635955.ch1.

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Andrei, Graciela, and Robert Snoeck. "Anti-HCMV Compounds." In Antiviral Drug Strategies. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635955.ch10.

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Iyidogan, Pinar, and Karen S. Anderson. "Lethal Mutagenesis as an Unconventional Approach to Combat HIV." In Antiviral Drug Strategies. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635955.ch11.

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Mani, Nagraj, Bhisetti G. Rao, Tara L. Kieffer, and Ann D. Kwong. "Recent Progress in the Development of HCV Protease Inhibitors." In Antiviral Drug Strategies. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635955.ch12.

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von Eije, Karin J., and Ben Berkhout. "Antiviral RNAi: How to Silence Viruses." In Antiviral Drug Strategies. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635955.ch13.

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Lew, Willard, Michael Z. Wang, Xiaowu Chen, James F. Rooney, and Choung Kim. "Neuraminidase Inhibitors as Anti-Influenza Agents." In Antiviral Drug Strategies. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635955.ch14.

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De Clercq, Erik. "From TIBO to Rilpivirine: The Chronicle of the Discovery of the Ideal Nonnucleoside Reverse Transcriptase Inhibitor." In Antiviral Drug Strategies. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527635955.ch15.

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Conference papers on the topic "Antiviral drug"

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Noviandy, Teuku Rizky, Aga Maulana, Ghifari Maulana Idroes, Rivansyah Suhendra, Razief Perucha Fauzie Afidh, and Rinaldi Idroes. "Machine Learning for Antiviral Drug Discovery: Application of XGBoost-TPE for Predicting Bioactivity of Hepatitis C Inhibitors." In 2024 International Conference on Electrical Engineering and Informatics (ICELTICs). IEEE, 2024. https://doi.org/10.1109/iceltics62730.2024.10776122.

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Chu, Justin Jang Hann. "Pandemic Preparedness: The Singapore Drug Repurposing Antiviral Strategy." In RExPO23. REPO4EU, 2023. http://dx.doi.org/10.58647/rexpo.23003.

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Smirnova, O. S., and I. D. Konstantinova. "BIOTECHNOLOGICAL SYNTHESIS THE ANTIVIRAL DRUG RIBAVIRIN ANALOGUES MODIFIED ON THE AMIDE GROUP." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-47.

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Ribavirin (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) is a well-known antiviral nucleoside. It has attracted interest for more than 40 years due to its unique spectrum of activity and still unclear mechanism of action. However, ribavirin has a high systemic toxicity and teratogenicity. Therefore, the search for new analogs of ribavirin with lower toxicity and high antiviral activity is still relevant.

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Cervo, A., A. Giacomelli, R. Rossotti, et al. "SC27 Real-world experience with doravirine in Italy: comparing three-drug and two-drug regimens." In Abstracts from the 17° Italian Conference on AIDS and Antiviral Research. BMJ Publishing Group Ltd, 2025. https://doi.org/10.1136/sextrans-icar-2025.92.

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Tynyo, Yaroslav Yaroslavovich, Elena Igorevna Yarygina, Varvara Andreevna Ustinova, Magdalena Trofimovna Vidrashko, and Galina Vadimovna Morozova. "ANTIVIRAL ACTIVITY OF ALLOKIN-ALPHA AGAINST BIRDS HERPESVIRUS." In Themed collection of papers from Foreign intemational scientific conference «Joint innovation - joint development». Medical sciences . Part 2. Ьу НNRI «National development» in cooperation with PS of UA. June 2023. Crossref, 2023. http://dx.doi.org/10.37539/230629.2023.95.55.023.

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Studies have been conducted to assess the effectiveness of the drug "Allokin-alpha" in the simulation of experimental viral infection in vivo at an agricultural poultry (day-old chickens) including: vaccination vaccine strain of HTV, monitoring of vaccinated poultry, the taking the study material from the vaccinated poultry, obtaining test material (an extract of feather follicles) from vaccinated birds. Specific antigen was detected in the epithelium of feather follicles by the diffusion precipitation in a gel). The results of the dynamics of antigen detection in the material obtained from th

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Fedulova, K. D., A. V. Ivanova, and N. V. Izmozherova. "Computer modeling of interaction between the antiviral drug riamilovir and HSP90." In PROCEEDINGS OF THE 3RD INTERNATIONAL CONFERENCE ON AUTOMOTIVE INNOVATION GREEN ENERGY VEHICLE: AIGEV 2018. Author(s), 2019. http://dx.doi.org/10.1063/1.5087315.

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Sun, Qingyang. "Advances on Molecular Design of Antiviral Drug Based on Deep Learning." In ICPHDS 2024: 2024 3rd International Conference on Public Health and Data Science. ACM, 2024. https://doi.org/10.1145/3718677.3718698.

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Ay, Emrah, and Nizami Duran. "Synergistic Efficacy of Eucalyptol with Acyclovir against HSV-2." In The 9th International Conference on Advanced Materials and Systems. INCDTP - Leather and Footwear Research Institute (ICPI), Bucharest, Romania, 2022. http://dx.doi.org/10.24264/icams-2022.iii.3.

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The increasing drug resistance in herpes viruses in recent years brings with it new treatment approaches. In recent years, it has been tried to overcome drug resistance, especially with the use of herbal products in combination with existing drugs. In this study, we aimed to investigate the effectiveness of eucalyptol in combination with acyclovir. A Vero cell line was used for toxicity tests and viral culture isolation studies in the study. The non-toxic concentrations of eucalyptol and acyclovir were determined by the MTT method. Antiviral efficacy studies were performed within non-toxic con

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Cosgriff, T. M., P. G. Canonico, L. Hodgson, et al. "RIBAVIRIN: STUDIES OF THE EFFECTS OF THE ANTIVIRAL DRUG ON PLATELET FUNCTION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644545.

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Ribavirin is a broad-spectrum antiviral drug which is presently undergoing testing in patients with AIDS-related complex. It has also been shown to have activity against respiratory syncytial virus, Sicilian sandfly fever virus, influenza A and B viruses, as well as several hemorrhagic fever viruses. It has proved effective in clinical trials in Lassa fever and shows promise as therapy for hemorrhagic fever with renal syndrome. Because platelet dysfunction may contribute significantly to hemostatic impairment in viral hemorrhagic fever, the effects of ribavirin on platelet function were measur

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Ripamonti, D., L. Comi, V. Bono, et al. "OC14 Changes in CD8+ T-cell activation after switching from suppressive 3-drug to 2-drug cART in people with HIV." In Abstracts from the 17° Italian Conference on AIDS and Antiviral Research. BMJ Publishing Group Ltd, 2025. https://doi.org/10.1136/sextrans-icar-2025.13.

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Reports on the topic "Antiviral drug"

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Hruby, Dennis E., and Tove C. Bolken. Smallpox Antiviral Drug. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada430565.

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Hruby, Dennis E. Smallpox Antiviral Drug. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada462351.

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Hruby, Dennis E. Smallpox Antiviral Drug. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada466159.

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Koizumi, Yoshiki, Syo Nakajim, Hirofumi Ohash, et al. Quantifying antiviral activity optimizes drug combinations against hepatitis C virus infection. Office of Scientific and Technical Information (OSTI), 2016. http://dx.doi.org/10.2172/1242919.

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Library, Spring. How Close are We Really to the HIV Cure? Spring Library, 2020. http://dx.doi.org/10.47496/sl.blog.20.

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The virus’ tricky, constantly mutating nature has so far made it impossible to develop an effective vaccine, even as the constantly improving antiviral drug classes have made HIV infection a manageable chronic health condition.

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Bunn, Sarah. COVID-19 therapies. Parliamentary Office of Science and Technology, 2020. http://dx.doi.org/10.58248/rr34.

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This article was updated on 1 May and again on 6 July. Since its original publication on 17 April, the number of COVID-19 clinical trials has increased from 524 to 2,378. There is no cure for COVID-19. Researchers are testing existing drugs to see if they act against SARS-CoV-2 or alleviate the symptoms of the disease. New drugs are also in development, but this is at a very early stage. Results from trials on existing drugs have already been reported with some positive findings. Dexamethasone is a cheap steroid drug that reduces the risk of death of ventilated patients by 35% and by 20% for p

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LI, jianhong, Zhuang LI, Yalin SHE, and Guohua LIN. Assessment of acupuncture for treating herpes zoster:a protocol for an umbrella systematic review and meta analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0010.

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Review question / Objective: Patients who suffer from HZ in line with the consensus of Chinese experts will be included, regardless of sex, race and time of onset . Those who diagnosed with PHN, auto-immune diseases, pregnant women will be excluded.Acupuncture, electroacupuncture, fire needle, skin acupuncture, plum blossom needle, auriculo-acupuncture all these such therapies in treating herpes zoster will be included.The control group’s treatment includes drug therapy (such as antiviral acyclovir nutritional nerve medicine or traditional Chinese medicine, etc.) ，sham acupuncture, placebo, no

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Turpin, James A. Drug Development and Convervation of Biodiversity in West and Central Africa/in Vitro Antiviral Screening of Plant Extracts and Isolates. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada383151.

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Ward, Keith B. Antiviral Drugs: Molecular Modeling and QSAR. Defense Technical Information Center, 1990. http://dx.doi.org/10.21236/ada256419.

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Tang, Jiqin, Gong Zhang, Jinxiao Xing, Ying Yu, and Tao Han. Network Meta-analysis of Heat-clearing and Detoxifying Oral Liquid of Chinese Medicines in Treatment of Children’s Hand-foot-mouth Disease：a protocol for systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.1.0032.

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Review question / Objective: The type of study was clinical randomized controlled trial (RCT). The object of study is the patients with HFMD. There is no limit to gender and race. In the case of clear diagnosis standard, curative effect judgment standard and consistent baseline treatment, the experimental group was treated with pure oral liquid of traditional Chinese medicine(A: Fuganlin oral liquid, B: huangzhihua oral liquid, C: Lanqin oral liquid, D: antiviral oral liquid, E: Huangqin oral liquid, F: Pudilan oral liquid, G: Shuanghuanglian oral liquid.)and the control group was treated with

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