Relevant bibliographies by topics / Antiviral plants

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Antiviral plants'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Antiviral plants"

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Orrego Escobar, Eduardo. "Plants with antiviral activity." Medwave 13, no. 10 (2013): e5854-e5854. http://dx.doi.org/10.5867/medwave.2013.10.5854.

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Cui, Qinghua, Ruikun Du, Miaomiao Liu, and Lijun Rong. "Lignans and Their Derivatives from Plants as Antivirals." Molecules 25, no. 1 (2020): 183. http://dx.doi.org/10.3390/molecules25010183.

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Lignans are widely produced by various plant species; they are a class of natural products that share structural similarity. They usually contain a core scaffold that is formed by two or more phenylpropanoid units. Lignans possess diverse pharmacological properties, including their antiviral activities that have been reported in recent years. This review discusses the distribution of lignans in nature according to their structural classification, and it provides a comprehensive summary of their antiviral activities. Among them, two types of antiviral lignans—podophyllotoxin and bicyclol, which
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İNCE KÖSE, Tuğçe, and Ayşe Mine GENÇLER ÖZKAN. "ANTIVIRAL HERBS." Ankara Universitesi Eczacilik Fakultesi Dergisi 46, no. 2 (2022): 505–22. http://dx.doi.org/10.33483/jfpau.1057473.

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Objective: Viruses are agents that can infect all kinds of living organisms, and the most important hosts are humans, animals, plants, bacteria and fungi. Viral diseases are responsible for serious morbidity and mortality worldwide, are a major threat to public health, and remain a major problem worldwide. The recently prominent Coronaviruses (CoVs) within this group belong to the Coronaviridae family, subfamily Coronavirinae, and are large (genome size 26−32 kb), enveloped, single-stranded ribonucleic acid (RNA ) viruses that can infect both animals and humans. The world has experienced three
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Morales-Pérez, Mayasil, Junior Vega Jiménez, and Ana Julia García-Milian. "Interacciones farmacológicas entre antivirales y plantas medicinales." Horizonte Sanitario 21, no. 2 (2022): 318–25. http://dx.doi.org/10.19136/hs.a21n2.4507.

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Objective: To identify medicinal plants that show pharmacological interactions with antiviral drugs. Materials and methods: A literature review carried out through the collection of articles in the PubMed, Scielo, Google academic databases. Information retrieved from each of the plants studied up to May 2018. An information sheet was prepared based on the information obtained and taking into account its usefulness and topicality. Results: 57.9% of the information was retrieved from academic Google. 47.9% of the total studies reviewed referred to clinical studies and 27% were investigations car
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Zahmanova, Gergana, Katerina Takova, Valeria Tonova, et al. "How Can Plant-Derived Natural Products and Plant Biotechnology Help Against Emerging Viruses?" International Journal of Molecular Sciences 26, no. 15 (2025): 7046. https://doi.org/10.3390/ijms26157046.

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Infectious diseases have been treated using plants and their compounds for thousands of years. This knowledge has enabled modern techniques to identify specific antiviral remedies and to understand their molecular mechanism of action. Numerous active phytochemicals, such as alkaloids, terpenoids, polyphenols (phenolic acids, flavonoids, stilbenes, and lignans), coumarins, thiophenes, saponins, furyl compounds, small proteins, and peptides, are promising options for treating and preventing viral infections. It has been shown that plant-derived products can prevent or inhibit viral entry into an
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Ferraro, G., A. Broussalis, V. Martino, G. Garcia, R. Campos, and J. D. Coussio. "ARGENTINE MEDICINAL PLANTS: ANTIVIRAL SCREENING." Acta Horticulturae, no. 306 (May 1992): 239–44. http://dx.doi.org/10.17660/actahortic.1992.306.28.

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Xie, Qi, and Hui-Shan Guo. "Systemic antiviral silencing in plants." Virus Research 118, no. 1-2 (2006): 1–6. http://dx.doi.org/10.1016/j.virusres.2005.11.012.

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Mukhtar, Muhammad, Mohammad Arshad, Mahmood Ahmad, Roger J. Pomerantz, Brian Wigdahl, and Zahida Parveen. "Antiviral potentials of medicinal plants." Virus Research 131, no. 2 (2008): 111–20. http://dx.doi.org/10.1016/j.virusres.2007.09.008.

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Jin, Liying, Mengna Chen, Meiqin Xiang, and Zhongxin Guo. "RNAi-Based Antiviral Innate Immunity in Plants." Viruses 14, no. 2 (2022): 432. http://dx.doi.org/10.3390/v14020432.

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Multiple antiviral immunities were developed to defend against viral infection in hosts. RNA interference (RNAi)-based antiviral innate immunity is evolutionarily conserved in eukaryotes and plays a vital role against all types of viruses. During the arms race between the host and virus, many viruses evolve viral suppressors of RNA silencing (VSRs) to inhibit antiviral innate immunity. Here, we reviewed the mechanism at different stages in RNAi-based antiviral innate immunity in plants and the counteractions of various VSRs, mainly upon infection of RNA viruses in model plant Arabidopsis. Some
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Ali Esmail Al-Snafi. "Medicinal plants with antiviral effect: A review." GSC Biological and Pharmaceutical Sciences 24, no. 1 (2023): 098–113. http://dx.doi.org/10.30574/gscbps.2023.24.1.0275.

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Several phytochemicals exhibited high level of antiviral activity. Medicinal plant possessed antiviral activity via many mechanisms included inhibition of viral replication, inhibition of the assembly of intracellular infectious virus particles, inhibition of viral infectivity, inhibition of RNA polymerase, DNA polymerase, viral neuraminidase, protease, reverse transcriptase and viral protein expression and many other mechanisms. The current review discuss the medicinal plants with antiviral activity with their mechanisms of action.
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Dissertations / Theses on the topic "Antiviral plants"

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Ho, Thien Xuan. "Antiviral gene silencing in plants." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509958.

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Kerr, Conor Gerard. "Investigation of antiviral activities of traditional Chinese medicinal plants." Thesis, Queen's University Belfast, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.602553.

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For thousands of years the practice of traditional medicine has been effective in the treatment of various infections using the plants and herbs that have been found and used locally with little or no adverse effects reported . One such documented system is that of traditional Chinese medicine (TCM) which is underlain by an artistic philosophy and supported by a wealth of anecdotal evidence of curative effect on human ailments. Many traditional medicinal plants have now been subjected to scientific based antiviral studies with their antiviral action being evaluated against both human and anima
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Ciomperlik, Jessica J. "Anti-viral RNAi and its suppression in plants." [College Station, Tex. : Texas A&M University, 2008. http://hdl.handle.net/1969.1/ETD-TAMU-2008-08-37.

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Sakamoto, Tetsu. "The tomato RLK superfamily: phylogeny and functional predictions about the role of the LRRII- RLK subfamily in antiviral defense." Universidade Federal de Viçosa, 2012. http://locus.ufv.br/handle/123456789/4804.

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Made available in DSpace on 2015-03-26T13:42:33Z (GMT). No. of bitstreams: 1 texto completo.pdf: 7011501 bytes, checksum: 91e769b2bb42693898b81b66b463f1e3 (MD5) Previous issue date: 2012-08-03<br>Fundação de Amparo a Pesquisa do Estado de Minas Gerais<br>Receptores cinases (RLKs) compõem uma grande famíla de proteínas transmembrânicas que possuem funções importantes na propagação e percepção de sinais celulares nas plantas. Em Arabidopsis thaliana, a superfamília de RLK é composta de mais de 600 membros e vários destes, principalmente aqueles que possuem repetições ricas em leucina (LRR), sã
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Ku, Chuen Fai. "Arylnapthalene liguans from justicia plants as potent broad-spectrum antiviral agents." HKBU Institutional Repository, 2020. https://repository.hkbu.edu.hk/etd_oa/779.

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Background: The emergence of viral diseases has been the major threat to public health and social stability. A hundred years ago, 1918 Spanish flu (H1N1) pandemic spread worldwide, and about 3% ~ 5% of the world's population died from the flu-related illnesses. It is known as the deadliest catastrophic pandemics in human history. There have been five Public Health Emergency of International Concern (PHEIC) declarations over the past decade, including the 2014 Ebola outbreak in west Africa, the 2016 Zika outbreak and the ongoing COVID-19 pandemic. There is always a new strain of virus emerging
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Ku, Chuen Fai. "Arylnaphthalene lignans from justicia plants as potent broad-spectrum antiviral agents." HKBU Institutional Repository, 2020. https://repository.hkbu.edu.hk/etd_oa/836.

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Background: The emergence of viral diseases has been the major threat to public health and social stability. A hundred years ago, 1918 Spanish flu (H1N1) pandemic spread worldwide, and about 3% ~ 5% of the world's population died from the flu-related illnesses. It is known as the deadliest catastrophic pandemics in human history. There have been five Public Health Emergency of International Concern (PHEIC) declarations over the past decade, including the 2014 Ebola outbreak in west Africa, the 2016 Zika outbreak and the ongoing COVID-19 pandemic. There is always a new strain of virus emerging
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Emamzadeh-Yazdi, Simin. "Antiviral, antibacterial and cytotoxic activities of South African plants containing cardiac glycosides." Diss., University of Pretoria, 2013. http://hdl.handle.net/2263/33163.

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South Africa has one of the richest and diverse floras in the world with over 30000 species of higher plants. There are approximately 3000 species of medicinal plants in South Africa. The discovery of active compounds in medicinal plants plays a strategic role in the phytochemical investigation of crude plant extracts. Secondary metabolites of medicinal plants are a major source of drugs for the treatment of various health disorders. Cardiac glycosides are one of the subgroups of steroids modified from terpenoids. The existence of cardiac glycosides in some plant species often indicates toxici
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Li, Wanfei. "Chemical synthesis of anti-HIV compounds based on the aryl naphthalene lignans identified from justicia plants." HKBU Institutional Repository, 2019. https://repository.hkbu.edu.hk/etd_oa/685.

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Background: Natural products have been a rich source for the discovery of lead compounds in modern drug discovery. 6,7'-Cyclolignans are a class of secondary metabolites which are widely distributed in more than 20 families. This important class of lignans continue to attract the interest of the pharmaceutical industry owing to their remarkable biological benefits, particularly for their anti-tumor and antiviral properties. Arylnaphthalene lignans (ANLs) belong to 6,7'-cyclolignans which contain a 2,3-dimethyl-1-phenyl-naphthalene core structure. ANLs are widely distributed in plants. Justicia
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Kalogirou, Maria. "Antiviral and quality effects of chemical elictors and Cucumber Mosaic Virus (CMV) infection on tomato plants and fruits." Thesis, Cranfield University, 2012. http://dspace.lib.cranfield.ac.uk/handle/1826/7278.

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Cucumber mosaic virus (CMV) has emerged as one of the most serious threats to tomato cultivation in Greece. In the present study the effects of Benzothiadiazoles (BTH) and pyraclostrobin against mechanically or aphid-transmitted CMV in tomato plants, of hybrid F1 Clodin, were investigated in greenhouse experiments. BTH was confirmed as capable of inducing systemic acquired resistance (SAR) in tomato seedlings against CMV, while pyraclostrobin was not. Responses to BTH application and/or CMV inoculation on Spanish tomato hybrid Delos (BTH, BTH+CMV, CMV treatments) were monitored during winter a
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GHOSH, Gopal Chandra. "Behavior of antibiotics and antiviral drugs in sewage treatment plants and risk associated with their widespread use under pandemic condition." 京都大学 (Kyoto University), 2009. http://hdl.handle.net/2433/85391.

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The concern for pharmaceutically active compounds (PhACs) as contaminants in the environment and the need to assess their environmental risk have greatly increased since the early nineties. Among PhACs, antibiotics and antiviral drugs are of important concern due to their role in growing antibiotic and antiviral drugs resistance among pathogenic bacteria and influenza viruses, respectively. Besides resistance issue, the compounds may upset sensitive ecosystems as they are designed to be highly bioactive. Clinically-important antibiotics are virtually ubiquitous contaminants in sewage water and
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Books on the topic "Antiviral plants"

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Watson, John M., and Ming-Bo Wang, eds. Antiviral Resistance in Plants. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-882-5.

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Kobayashi, Kappei, and Masamichi Nishiguchi, eds. Antiviral Resistance in Plants. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9635-3.

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Meyer, Chessin, DeBorde Dan, and Zipf Allan, eds. Antiviral proteins in higher plants. CRC Press, 1995.

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Song, Baoan, Linhong Jin, Song Yang, and Pinaki S. Bhadury. Environment-Friendly Antiviral Agents for Plants. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-03692-7.

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Song, Bao'an. Environment-friendly antiviral agents for plants. Springer, 2010.

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Akhtar, Nadeem, Azamal Husen, Vagish Dwibedi, and Santosh Kumar Rath. Promising Antiviral Herbal and Medicinal Plants. CRC Press, 2023. http://dx.doi.org/10.1201/9781003329169.

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Ray, A. B. Medicinal properties of plants: Antifungal, antibacterial, and antiviral activities. International Book Distributing Co., 2004.

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J, Cousins D., and C. A. B. International, eds. Plants with antimicrobial properties: A bibliography compiled from the CAB abstracts database. CAB International, 1995.

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Hudson, James B. Antiviral Compounds from Plants. Taylor & Francis Group, 2018.

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Hudson, James B. Antiviral Compounds from Plants. Taylor & Francis Group, 2018.

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Book chapters on the topic "Antiviral plants"

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Anderssen, Robert S., and Peter M. Waterhouse. "Modeling Antiviral Resistance in Plants." In Methods in Molecular Biology. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-882-5_10.

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Venkateish, V. P., V. Nivya, V. Vani, V. Baskaran, and P. Madan Kumar. "Antiviral Activity of Medicinal Plants." In Traditional Herbal Therapy for the Human Immune System. CRC Press, 2021. http://dx.doi.org/10.1201/9781003137955-3.

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Beutler, John A., John H. Cardellina, James B. McMahon, Robert H. Shoemaker, and Michael R. Boyd. "Antiviral and Antitumor Plant Metabolites." In Phytochemistry of Medicinal Plants. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-1778-2_3.

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Song, Baoan, Linhong Jin, Song Yang, and Pinaki S. Bhadury. "The Heterocyclic Antiviral Agents." In Environment-Friendly Antiviral Agents for Plants. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-03692-7_5.

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Devi, M. Bilashini, S. R. Assumi, H. D. Talang, Vanlalruati, and Pooja Bhadrecha. "Medicinal Plants and Herbs." In Promising Antiviral Herbal and Medicinal Plants. CRC Press, 2023. http://dx.doi.org/10.1201/9781003329169-3.

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Kumari, Reena, and Prachi Vaid. "Prospects of Medicinal Plants and Plant Compounds as Anti-Human Herpes Virus Drugs." In Promising Antiviral Herbal and Medicinal Plants. CRC Press, 2023. http://dx.doi.org/10.1201/9781003329169-15.

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Kaur, Yadveer, Gurpreet Kaur, and Gursharan Kaur. "Rotavirus and Medicinal Plants/Herbs." In Promising Antiviral Herbal and Medicinal Plants. CRC Press, 2023. http://dx.doi.org/10.1201/9781003329169-16.

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Elsharkawy, Mohsen Mohamed. "Antiviral Activity of Nanoparticles in Plants." In Nanotechnology in Plant Health. CRC Press, 2024. http://dx.doi.org/10.1201/9781003375104-21.

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Sharma, Swati, and Monika Thakur. "Human Papillomavirus and Medicinal Plants/Herbs." In Promising Antiviral Herbal and Medicinal Plants. CRC Press, 2023. http://dx.doi.org/10.1201/9781003329169-17.

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Kumar, Abhijit, and Pooja Bhadrecha. "Medicinal Plants/Herbs and Influenza Virus." In Promising Antiviral Herbal and Medicinal Plants. CRC Press, 2023. http://dx.doi.org/10.1201/9781003329169-11.

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Conference papers on the topic "Antiviral plants"

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Marliyana, Soerya Dewi, Maulidan Firdaus, Muhamad Widyo Wartono, Diana Inas Utami, and Uly Wulan Apriani. "Evaluation of the Antibacterial Activity of Pinostrobin Derivative Compounds from Ethylation and Allylation Reactions." In 8th International Conference on Advanced Material for Better Future. Trans Tech Publications Ltd, 2025. https://doi.org/10.4028/p-s3ucax.

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Temu Kunci (Kaempferia pandurata Roxb.) is one of the plants from the Zingiberaceae family that contains secondary metabolites derived from flavonoids. Studies on the bioactivity of flavonoid compounds from this species have shown various biological activities such as antibacterial, antioxidant, antiviral, antitumor, antipyretic, anti-inflammatory, analgesic, and insecticidal properties. Pinostrobin (5-hydroxy-7-methoxy flavanone) (1) is the major flavonoid found in the rhizomes of this plant and has been successfully derivatized through ethylation and allylation reactions. Two compounds were
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Suprunova, T. P., N. V. Markin, A. N. Ignatov, A. G. Solovyov, N. O. Kalinina, and M. E. Talyansky. "Use of dsRNA-based antiviral compounds to protect potato plants." In Растениеводство и луговодство. Тимирязевская сельскохозяйственная академия, 2020. http://dx.doi.org/10.26897/978-5-9675-1762-4-2020-132.

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One of the most important food crops in the world, the potato (Solanum tuberosum L.) is infected with many viruses, of which the y virus (Potato virus Y, PVY) is the most important economically, causing significant crop losses. Several alternative methods of dsRNA delivery have been tested, with the most promising being spray - induced gene silencing (SIGS). The results showed a high effect of preventive use of dsRNA. Treatment with the initial working concentration of dsRNA protected 100% and 65% of plants from virus propagation for 14 and 21 days, respectively, and 65% of plants were protect
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Todorov, Daniel, Anton Hinkov, Kalina Shishkova, et al. "Antiviral treasure hunt: Novel compounds from plants and invertebrates." In RAD Conference. RAD Centre, 2023. http://dx.doi.org/10.21175/rad.abstr.book.2023.7.4.

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Marschik, T., and K. Zitterl-Eglseer. "Antiviral Medicinal Plants of Veterinary Importance (A Literature Review)." In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736812.

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Gosteva, T. A., V. V. Solodky, V. V. Zolin, and O. P. Os’kina. "TOXICITY OF ESSENTIAL OILS AND THEIR ANTIVIRAL ACTIVITY AGAINST THE SARS-COV-2 VIRUS." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-180.

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Essential oils of some plants are used in medicine as anti-inflammatory, immunomodulatory, antimicrobial and antiviral agents. Natural essential oils perform the functions of protecting plants from pests, accidents, viruses, as well as from low and high temperatures [1–3].
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Shurupova, М. N., V. S. Shurupov, and R. S. Romanets. "To the resource study of the Rosaceae plants with antiviral activity in Southern Siberia." In Problems of studying the vegetation cover of Siberia. TSU Press, 2020. http://dx.doi.org/10.17223/978-5-94621-927-3-2020-48.

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The survey is directed at revealing of the natural reserves of 9 species of Rosaceae family in the Southern Siberia: Agrimonia pilosa Ledeb., Alchemilla vulgaris L. s.l., Filipendula ulmaria (L.) Maxim., F. vulgaris Moench., F. stepposa Juz., and Pentaphylloides fruticosa (L.) O. Schwarz. Raw materials of these species are considered as a strategically important source of biologically active substances with antiviral activity being perspective for pharmaceutic branch. For habitats from some regions of Southern Siberia, the resource indicators of these species are given, such as the coefficient
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Kolychikhina, M. S. "Positive effect of preparations with antiviral properties on potato productivity." In Растениеводство и луговодство. Тимирязевская сельскохозяйственная академия, 2020. http://dx.doi.org/10.26897/978-5-9675-1762-4-2020-111.

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In the small-plot experiment of the Russian State Agrarian University - Moscow Timiryazev Agricultural Academy against potato viruses in 2014-2019 were tested some kinds of preparations with antiviral activity: Pharmayod, GS (100 g/l of iodine); Immunocytophyte, TAB (20 g/kg arachidonic acid ethyl ester); Ecogel, WS (30 g/l of chitosan lactate); Amulet, TAB (composition of linear polyaminosaccharides (chitosan) in succinic acid solution); Zerox, WS (3000 mg /l colloidal silver); Viron, WS (biostimulant based on urea and citric acid with the addition of essential oils). According to the results
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Shahrajabian, Mohamad Hesam, and Wenli Sun. "Chinese Medicinal Plants with Antiviral Activities for Treatment of the Common Cold and Flu." In Foods 2023. MDPI, 2023. http://dx.doi.org/10.3390/foods2023-15058.

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Самарская, В. О., Н. А. Спеченкова, Н. В. Маркин, et al. "MECHANISMS INVOLVED IN THE PROTECTIVE ANTIVIRAL RESPONSE OF POTATO PLANTS DURING EXOGENOUS APPLICATION OF dsRNA AGAINST POTATO VIRUS Y." In Биотехнология в растениеводстве, животноводстве и сельскохозяйственной микробиологии. Crossref, 2022. http://dx.doi.org/10.48397/arriab.2022.22.xxii.029.

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Технология опрыскивания растений экзогенной двуцепочечной РНК (дцРНК) или спрей-индуцированный сайленсинг генов применяется для индукции устойчивости растений к вирусам сельскохозяйственных культур [1]. В настоящей работе мы использовали этот подход для обработки растений картофеля Solanum tuberosum препаратами дцРНК, гомологичной консервативному фрагменту гена репликазы Y вируса картофеля (дцРНК-YВК), и изучили влияние экзогенной дцРНК на защитный ответ растений, основанный на механизмах специфической РНК интерференции (РНКи) [2] и неспецифического иммунитета, индуцируемого молекулярными патт
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Mehrbod, P., M. Ali Abdalla, F. Fotouhi, J. Nicolaas Eloff, LJ McGaw, and O. Fasina Folorunso. "Antiviral potential against influenza A virus of crude extracts from five South African medicinal plants." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608390.

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Reports on the topic "Antiviral plants"

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Loebenstein, Gad, M. Chessin, and Abed Gera. Resistance Mechanisms to Viruses in Plants Associated with Antiviral Substances (Inhibitors of Virus Replication). United States Department of Agriculture, 1987. http://dx.doi.org/10.32747/1987.7695597.bard.

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Gal-On, Amit, Shou-Wei Ding, Victor P. Gaba, and Harry S. Paris. role of RNA-dependent RNA polymerase 1 in plant virus defense. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597919.bard.

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Objectives: Our BARD proposal on the impact of RNA-dependent RNA polymerase 1 (RDR1) in plant defense against viruses was divided into four original objectives. 1. To examine whether a high level of dsRNA expression can stimulate RDR1 transcription independent of salicylic acid (SA) concentration. 2. To determine whether the high or low level of RDR1 transcript accumulation observed in virus resistant and susceptible cultivars is associated with viral resistance and susceptibility. 3. To define the biogenesis and function of RDR1-dependent endogenous siRNAs. 4. To understand why Cucumber mosai
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Wang, X. F., and M. Schuldiner. Systems biology approaches to dissect virus-host interactions to develop crops with broad-spectrum virus resistance. United States-Israel Binational Agricultural Research and Development Fund, 2020. http://dx.doi.org/10.32747/2020.8134163.bard.

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More than 60% of plant viruses are positive-strand RNA viruses that cause billion-dollar losses annually and pose a major threat to stable agricultural production, including cucumber mosaic virus (CMV) that infects numerous vegetables and ornamental trees. A highly conserved feature among these viruses is that they form viral replication complexes (VRCs) to multiply their genomes by hijacking host proteins and remodeling host intracellular membranes. As a conserved and indispensable process, VRC assembly also represents an excellent target for the development of antiviral strategies that can b
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Whitham, Steven A., Amit Gal-On, and Victor Gaba. Post-transcriptional Regulation of Host Genes Involved with Symptom Expression in Potyviral Infections. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7593391.bard.

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Understanding how RNA viruses cause disease symptoms in their hosts is expected to provide information that can be exploited to enhance modern agriculture. The helper component-proteinase (HC-Pro) protein of potyviruses has been implicated in symptom development. Previously, we demonstrated that symptom expression is associated with binding of duplex small-interfering-RNA (duplex-siRNA) to a highly conserved FRNK amino acid motif in the HC-Pro of Zucchini yellow mosaic virus (ZYMV). This binding activity also alters host microRNA (miRNA) profiles. In Turnip mosaic virus (TuMV), which infects t
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Chejanovsky, Nor, and Bruce A. Webb. Potentiation of Pest Control by Insect Immunosuppression. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7592113.bard.

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The restricted host range of many baculoviruses, highly pathogenic to Lepidoptera and non-pathogenic to mammals, limits their use to single or few closely related Lepidopteran species and is an obstacle to extending their implementation for pest control. The insect immune response is a major determinant of the ability of an insect pathogen to efficiently multiply and propagate. We have developed an original model system to study the Lepidopteran antiviral immune response based on Spodoptera littoralis resistance to AcMNPV (Autographa californica multiple nucleopolyhedrovirus) infection and the
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Turpin, James A. Drug Development and Convervation of Biodiversity in West and Central Africa/in Vitro Antiviral Screening of Plant Extracts and Isolates. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada383151.

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Gafni, Yedidya, Moshe Lapidot, and Vitaly Citovsky. Dual role of the TYLCV protein V2 in suppressing the host plant defense. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7597935.bard.

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TYLCV-Is is a major tomato pathogen, causing extensive crop losses in Israel and the U.S. We have identified a TYLCV-Is protein, V2, which acts as a suppressor of RNA silencing. Intriguingly, the counter-defense function of V2 may not be limited to silencing suppression. Our recent data suggest that V2 interacts with the tomato CYP1 protease. CYP1 belongs to the family of papain-like cysteine proteases which participate in programmed cell death (PCD) involved in plant defense against pathogens. Based on these data we proposed a model for dual action of V2 in suppressing the host antiviral defe
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Lapidot, Moshe, and Vitaly Citovsky. molecular mechanism for the Tomato yellow leaf curl virus resistance at the ty-5 locus. United States Department of Agriculture, 2016. http://dx.doi.org/10.32747/2016.7604274.bard.

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Tomato yellow leaf curl virus (TYLCV) is a major pathogen of tomato that causes extensive crop loss worldwide, including the US and Israel. Genetic resistance in the host plant is considered highly effective in the defense against viral infection in the field. Thus, the best way to reduce yield losses due to TYLCV is by breeding tomatoes resistant or tolerant to the virus. To date, only six major TYLCV-resistance loci, termed Ty-1 to Ty-6, have been characterized and mapped to the tomato genome. Among tomato TYLCV-resistant lines containing these loci, we have identified a major recessive quan
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