Academic literature on the topic 'Asymmetric total synthesis'

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Journal articles on the topic "Asymmetric total synthesis"

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Chen, Fen-Er, and Lei Chen. "Total Synthesis of Camptothecins: An Update." Synlett 28, no. 10 (2017): 1134–50. http://dx.doi.org/10.1055/s-0036-1588738.

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Over the last few decades, considerable research efforts have been directed toward the development of effective chemical syntheses of camptothecin and its analogs. The last comprehensive review of this area was published in 2003 and many effective new methods have since been reported for the stereoselective synthesis of the camptothecin alkaloids. In this account, we have summarized most of the novel synthetic approaches developed for the synthesis of camptothecins during the last decade. We have focused on strategies for the construction of the pentacyclic ring system and the different method
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Huang, Deng-Ming, Hui-Jing Li, Jun-Hu Wang, and Yan-Chao Wu. "Asymmetric total synthesis of talienbisflavan A." Organic & Biomolecular Chemistry 16, no. 4 (2018): 585–92. http://dx.doi.org/10.1039/c7ob02837g.

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The first asymmetric total syntheses of talienbisflavan A and bis-8,8′-epicatechinylmethane as well as a facile synthesis of bis-8,8′-catechinylmethane has been accomplished from readily available starting materials by using a newly developed direct regioselective methylenation of catechin derivatives as one of the key steps.
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Szcześniak, Piotr, Olga Staszewska-Krajewska, and Jacek Mlynarski. "Asymmetric total synthesis of (+)-asenapine." Organic & Biomolecular Chemistry 17, no. 12 (2019): 3225–31. http://dx.doi.org/10.1039/c9ob00178f.

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Zhang, Yan-Hui, Rong Liu, and Bo Liu. "Total synthesis of nannocystin Ax." Chemical Communications 53, no. 40 (2017): 5549–52. http://dx.doi.org/10.1039/c7cc00469a.

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Total synthesis of nannocystin Ax has been accomplished concisely. The key elements in this total synthesis feature Kobayashi's remote asymmetric induction with vinylketene silyl N,O-acetal, Roush's asymmetric crotylboration of aldehyde, Mitsunobu's esterification and macrocyclization via Stille cross-coupling.
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Marumoto, Shinji, and Hiroshi Kogen. "Asymmetric Total Synthesis of Epolactaene." Journal of Synthetic Organic Chemistry, Japan 58, no. 3 (2000): 183–91. http://dx.doi.org/10.5059/yukigoseikyokaishi.58.183.

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Chen, Yang, and Wei-Dong Z. Li. "Asymmetric Total Synthesis of (-)-Cephalotaxine." Chinese Journal of Organic Chemistry 37, no. 8 (2017): 1885. http://dx.doi.org/10.6023/cjoc201705025.

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MUKAIYAMA, Teruaki, Isamu SHIINA, Hayato IWADARE, et al. "Asymmetric Total Synthesis of Taxol." Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences 73, no. 6 (1997): 95–100. http://dx.doi.org/10.2183/pjab.73.95.

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Koulocheri, Sofia D., and Serkos A. Haroutounian. "Asymmetric total synthesis of (−)-prosophylline." Tetrahedron Letters 40, no. 37 (1999): 6869–70. http://dx.doi.org/10.1016/s0040-4039(99)01387-8.

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Aoyagi, Sakae, Ryuta Tanaka, Masaichi Naruse, and Chihiro Kibayashi. "Asymmetric total synthesis of (−)-epibatidine." Tetrahedron Letters 39, no. 25 (1998): 4513–16. http://dx.doi.org/10.1016/s0040-4039(98)00803-x.

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Yang, Cui-Fen, Yi-Ming Xu, Li-Xin Liao, and Wei-Shan Zhou. "Asymmetric total synthesis of (+)-desoxoprosophylline." Tetrahedron Letters 39, no. 50 (1998): 9227–28. http://dx.doi.org/10.1016/s0040-4039(98)02129-7.

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Dissertations / Theses on the topic "Asymmetric total synthesis"

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Figuccia, Aude L. A. "Total asymmetric syntheses of iminosugars." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:7075b45f-e3e1-4ae6-a544-4d6e54d4714e.

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This thesis is concerned with the development of ring-closing iodoamination and ringexpansion methodology and its subsequent application to the asymmetric syntheses of pyrrolidine and piperidine iminosugars. <strong>Chapter 1</strong> highlights the remarkable biological properties displayed by iminosugars and introduces methods for the formation of the pyrrolidine and piperidine sub-classes. <strong>Chapter 2</strong> describes investigations into the ring-closing iodoamination of bishomoallylic amines which occurs with concomitant <i>N</i>-debenzylation to give an iodomethyl pyrrolidine scaf
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Grainger, Damian Mark. "Towards the total asymmetric synthesis of Euonyminol." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428333.

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Nieh, Ling-Fu. "Towards the asymmetric total synthesis of (-)-lycorine." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/44241.

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The application of organocatalysis has expanded significantly in recent years. Organocatalysts can give good enantioselectitvity and hence provide an efficient access to chiral building blocks for organic synthesis. The first chapter in this thesis discusses the possibility to improve the enantioselectivity of the asymmetric Kornblum-DeLaMare (KDLM) rearrangement on a six-membered cyclic endoperoxide. Toste has developed efficient bifunctional catalysts derived from quinine and quinidine for the asymmetric KDLM rearrangement on eight- and seven-membered cyclic endoperoxides, but these catalyst
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Hayes, J. F. "Studies towards the total asymmetric synthesis of macbecin." Thesis, University of Southampton, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374854.

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Zhang, Yan Crimmins Michael T. "Total synthesis of (-)-mucocin and studies toward the asymmetric total synthesis of brianthein A." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1414.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Apr. 25, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Chemistry." Discipline: Chemistry; Department/School: Chemistry.
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Kuang, Liping, and 况利平. "Asymmetric formal total synthesis of cortistatins A and J." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/208604.

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Ford, M. J. "Asymmetric total synthesis of alkaloids and seco-iridoids." Thesis, University of Manchester, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234212.

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Papillon, Julien Pierre Nicolas. "Studies towards the asymmetric total synthesis of oxazolomycin." Thesis, University of York, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288241.

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Webber, Matthew J. "Towards the first asymmetric total synthesis of (-)-Euonyminol." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/5612.

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(–)-euonyminol is a poly-oxygenated sesquiterpene which was first isolated in 1953 by Beroza. It was isolated by the saponification of a mixture of four alkaloids from Tripterygium wilfordii Hook, a member of the Celastraceae plant family. Since its discovery, (–)-euonyminol has been found to be a common core for a plethora of other Celastraceae natural products. Among these are hypogluanine B and triptonine B, two potent anti-HIV compounds. In this thesis, an overview of the natural products of the Celastraceae is given, highlighting euonyminol as a core of high value both in terms of biologi
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Mitra, Soumya. "Total synthesis of gomisin O asymmetric total syntheses of eupomatilones 1, 2 and 5; and studies towards total synthesis of mayolide A /." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1189449580.

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Books on the topic "Asymmetric total synthesis"

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Taber, Douglass. Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.001.0001.

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Organic synthesis is a vibrant and rapidly evolving field; we can now cyclize amines directly onto alkenes. Like the first two books in this series, Organic Synthesis: State of the Art 2003-2005 and Organic Synthesis: State of the Art 2005-2007, this reference leads readers quickly to the most important recent developments. Two years of Taber's popular weekly online column, "Organic Chemistry Highlights", as featured on the organic-chemistry.org website, are consolidated here, with cumulative indices of all three volumes in this series. Important topics that are covered range from powerful new
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Book chapters on the topic "Asymmetric total synthesis"

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Kilenyi, S. N. "Asymmetric total synthesis." In Asymmetric Synthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-1346-5_7.

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Movassaghi, Mohammad, and Sunkyu Han. "Total Synthesis of All (-)-Agelastatin Alkaloids." In Asymmetric Synthesis II. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527652235.ch49.

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Gaich, Tanja, and Johann Mulzer. "Biomimetic Total Synthesis of the Penifulvin Family." In Asymmetric Synthesis II. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527652235.ch22.

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Nilewski, Christian, and Erick M. Carreira. "Tactics and Strategies in the Total Synthesis of Chlorosulfolipids." In Asymmetric Synthesis II. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527652235.ch44.

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Barroso, Santiago, and Adriaan J. Minnaard. "Asymmetric Catalysis in the Total Synthesis of Lipids and Polyketides." In Asymmetric Synthesis II. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527652235.ch27.

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Ishikawa, Hayato, and Yujiro Hayashi. "Total Synthesis of Oseltamivir and ABT-341 Using One-Pot Technology." In Asymmetric Synthesis II. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527652235.ch9.

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Gademann, Karl. "Strategies for the Asymmetric Total Synthesis of Natural Products: ‘‘Chiral Pool’’ versus Chiral Catalysts." In Asymmetric Synthesis II. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527652235.ch40.

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Xie, Weiqing, and Dawei Ma. "Total Synthesis of Complex Natural Products via Dearomatization." In Asymmetric Dearomatization Reactions. Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527698479.ch13.

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Burns, Noah Z., and Phil S. Baran. "Point-to-Planar Chirality Transfer in Total Synthesis: Scalable and Programmable Synthesis of Haouamine A and Its Atropisomer." In Asymmetric Synthesis II. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527652235.ch2.

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Liu, Yun-Lin, and Jian Zhou. "Multicatalyst System Mediated Asymmetric Reactions in Total Synthesis." In Multicatalyst System in Asymmetric Catalysis. John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9781118846919.ch10.

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Conference papers on the topic "Asymmetric total synthesis"

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Ishikawa, Eloisa E., and Luiz F. Silva Jr. "Studies Towards Asymmetric Total Synthesis of Populene D." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013913144428.

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Hoppe, Dieter, and M. Martínez. "Total Synthesis of (-)-a-kainic Acid by(-)-sparteine-mediated Asymmetric Deprotonation/Cycloalkylation." In The 9th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2005. http://dx.doi.org/10.3390/ecsoc-9-01470.

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DENIAU, Eric, and Stéphane LEBRUN. "Asymmetric synthesis of a to nitrogen substituted azaheterocycles. Application to the total synthesis of S-(-)-Anabasine." In The 19th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2015. http://dx.doi.org/10.3390/ecsoc-19-a032.

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Deniau, Eric. "Total synthesis of (–)-herbaric acid through organocatalyzed asymmetric halolactonization of acrylate-type benzoic acids." In The 21st International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2017. http://dx.doi.org/10.3390/ecsoc-21-04725.

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Wang, Yiou, Jiang Zhe, Prashanta Dutta, and Gary J. Cheng. "A Hybrid Rapid Microfluidic Mixer Utilizing Electrokinetic Relay and Asymmetric Flow Geometries for Lab-on-a-Chip Applications." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-80423.

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Numerical study on a rapid micromixer based on hybrid electrokinetic relay and asymmetric serpentine structures is presented. Effective mixing of liquids is essential in many applications such as drug delivery, DNA analysis/sequencing, pheromone synthesis in micro bioreactors, and biological/chemical agent detections. Rapid mixing can reduce the analysis time and permit high throughput in lab-on-a-chip or micro total analysis systems (μTAS). The proposed hybrid mixing takes advantages of both mixing enhancements induced by asymmetric flow geometries and the electrokinetic relay actuating. Simu
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