Log in

Relevant bibliographies by topics / Benzimidazole; 1 / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Benzimidazole; 1.

Dissertations / Theses on the topic 'Benzimidazole; 1'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 28 dissertations / theses for your research on the topic 'Benzimidazole; 1.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Namal, Imge. "Synthesis And Electrochemical Studies Of Fluorene And Benzimidazole Containing Conjugated Polymers." Master's thesis, METU, 2013. http://etd.lib.metu.edu.tr/upload/12615382/index.pdf.

Full text

Abstract:

The synthesis and characterization of two donor acceptor type conjugated polymers were investigated. The electrochemical properties were examined using cyclic voltammetry, spectroelectrochemistry and kinetic studies. The increase in the alkyl chain length attached to the fluorene unit was investigated by the corresponding electrochemical characteristics. The synthesis was carried out via Stille coupling of 4,7- dibromo-4&#039<br>-(tert-butyl)spiro[benzo[d]imidazole-2,1&#039<br>cyclohexane] and 2,5- bis(tributylstannyl)thiophene with 9,9-dihexyl-9H fluorene and 9,9-didodecyl-9H fluorene respect

APA, Harvard, Vancouver, ISO, and other styles

2

Barsys, Vygantas. "Benzimidazolų ir dihidropiridinų poveikio kraujagyslių segmentų ir papiliarinių raumenų izometrinei funkcijai įvertinimas." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2013~D_20140106_083915-09957.

Full text

Abstract:

Šio eksperimentinio darbo tikslas buvo įvertinti 1,4-dihidropiridino ir benzimidazolo junginių poveikį jūros kiaulyčių širdies papiliarinių raumenų izometrinei funkcijai bei žmogaus kraujagyslių segmentų susitraukimui ir atsipalaidavimui. Buvo atlikti eksperimentiniai tyrimai su izoliuotais jūros kiaulyčių širdies papiliarinių raumenų preparatais ir izoliuotais žmogaus v.saphena magna ir a.thoracica interna kraujagyslių segmentais. Kraujagyslių preparatai gauti iš pacientų, kuriems buvo atliekamos širdies vainikinių arterijų jungčių suformavimo operacijos LSMU ligoninės Kauno klinikos Kardioch

APA, Harvard, Vancouver, ISO, and other styles

3

Huang, Shih-Huang. "Synthesis and characterization of 2-chloro-3-benzylthiopyrrolo[1,2-a]- benzimidazol-1-one and 2,3-di(benzylthio)pyrrolo[1,2-a]benzimidazol-1-one." Thesis, University of North Texas, 2003. https://digital.library.unt.edu/ark:/67531/metadc4415/.

Full text

Abstract:

The reaction between o-phenylenediamine and 2,3-dichloromaleic anhydride has been probed and found to give 2,3-dichloropyrrolo[1,2-a]- benzimidazol-1-one as the major product. Chlorine substitution in 2,3-dichloropyrrolo[1,2-a]benzimidazol-1-one by added benzylthiol occurs in the presence of pyridine to provide the corresponding monosulfide and disulfide derivatives. The first benzylthiol ligand undergoes reaction at the C-3 position of the five-membered pyrrolo-1-one ring, with the addition of the second benzylthiol ligand occurring at the remaining chlorine-substituted carbon. The mono- and

APA, Harvard, Vancouver, ISO, and other styles

4

Cerda, Cavieres Christopher David. "Síntesis de Derivados N-Benzoil-2-(2-Nitrofenil)-1-Hbenzimidazoles. Desarrollo de Metodologías Analíticas y Caracterización Fisicoquímica de N-(p-Flúor)-Benzoil-2-(2-Nitrofenil)-Benzimidazol y N-(p-Nitro)-Benzoil -2-(2 Nitrofenil)-Benzimidazol." Tesis, Universidad de Chile, 2008. http://repositorio.uchile.cl/handle/2250/105700.

Full text

Abstract:

La presente Memoria se orientó al estudio y caracterización electro-analítica de una serie de derivados N-(4-R-benzoil)-2-(2-nitrofenil)-1-H-benzimidazoles como sustratos de interés biológico. Los compuestos estudiados fueron sintetizados a partir de 2-(o-nitrofenil)-benzimidazol, generado por condensación entre 1,2-diamino-benceno y 2-nitrobenzaldehído. Posterior reacción del benzimidazol con una serie de cloruros de aroílo, generó la serie de cuatro N-(4-R-benzoil)-2-(2-nitrofenil)-1-H-benzimidazoles en buen rendimiento (R = NO2, Cl, F), con la excepción del producto denominado PMNB (R =

APA, Harvard, Vancouver, ISO, and other styles

5

Wu, Guanmin. "Synthesis and Characterization of 2,3-Dichloropyrrolo[1,2-a]benzimidazol-1-one and Its Methylthiol Derivatives." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5238/.

Full text

Abstract:

Condensation of 2,3-dichloromaleic anhydride and o-phenylenediamine in refluxing toluene affords the three compounds 2,3-dichloro-N-o-C6H4(NH2)maleimide (1), N,N¢-o-C6H4-bis(2,3-dichloromaleimide) (2), and 2,3-dichloropyrrolo[1,2-a]benzimidazol-1-one (3), with compound 1 as the major product. Repeating the same reaction in the presence of added PTSA furnishes compound 3 as the major product. Treatment of 3 with methylthiol in the presence of pyridine affords monosulfide compounds 2-chloro-3-methylthiopyrrolo[1,2-a]benzimidazol-1-one (4) and and the disulfide derivatives 2,3-di(methylthio)pyrro

APA, Harvard, Vancouver, ISO, and other styles

6

Zaher, Damien. "Early transition metal benzimidazolyl-based catalysts for olefin polymerisation and co-polymerisation." Thesis, Imperial College London, 2007. http://hdl.handle.net/10044/1/8352.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Taleb, Abbass. "Recherche de composés antiparasitaires : voie d'accès aux 1-alkylbenzimidazole-4,7-diones et synthèse régiospécifique d'imidazo[4,5-g]quinoléine-4,9-diones." Lyon 1, 2005. http://www.theses.fr/2005LYO10293.

Full text

Abstract:

Le thème de recherche développé dans ce mémoire est orienté vers la synthèse de produits potentiellement actifs contre un protozoaire intracellulaire : Toxoplasma gondii. La purine nucléoside phosphorylase (PNP) étant une enzyme indispensable au développement de ce parasite, une recherche de composés inhibiteurs de celle-ci a été initiée. Des dérivés de benzimidazole-4,7-diones ont alors montré une bonne activité dans ce domaine. La première phase de nos travaux a consisté à améliorer la voie d'accès à de tels composés. Ainsi une nouvelle méthodologie a été mise au point, qui permet d'accéder

APA, Harvard, Vancouver, ISO, and other styles

8

Ishak, Dridi Islem. "Synthèse stéréosélective et réactivité des 4-hydroxy-1-boryl-1-allénylsilanes. Synthèse et étude théorique de nouveaux dérivés de dimères benzimidazolo-1,3,5,2-triazaphosphorine-2-oxydes." Thesis, Sorbonne université, 2019. https://accesdistant.sorbonne-universite.fr/login?url=http://theses-intra.upmc.fr/modules/resources/download/theses/2019SORUS573.pdf.

Full text

Abstract:

Cette thèse a portée sur deux sujets différents. D’abord la synthèse des 1-silylalléneboranes a été étudiée, pour la première fois, à partir d’époxyde acétylénique et d’un silylborane. Cette méthode permet la préparation stéréosélective et stéréospécifique des allénylboranes via un mécanisme SNi anti. Par la suite, la propargylation des aldéhydes par l’intermédiaire de ces allènes a permis d’accéder de façon stéréosélective aux 2-alcynyldiols-1,3 correspondants. Un état de transition fermé à six chainants a été proposé pour cette dernière transformation qui procède via un mécanisme SE2’. L’éte

APA, Harvard, Vancouver, ISO, and other styles

9

Badarau, Eduard. "Conception, synthèse et évaluation biologique de nouvelles classes de ligands sérotoninergiques 5-HT7." Phd thesis, Université d'Orléans, 2009. http://tel.archives-ouvertes.fr/tel-00480279.

Full text

Abstract:

Parmi tous les neurotransmetteurs identifiés à ce jour, la sérotonine (5-hydroxytryptamine, 5-HT) est impliquée dans le système le plus complexe de récepteurs. Parmi eux, les récepteurs 5-HT7 qui sont les derniers découverts (1993) semblent avoir des implications multiples tant au niveau central que périphérique. Le potentiel thérapeutique représenté par la découverte de ligands 5-HT7 sélectifs vis-à-vis d'autres RCPGs a motivé notre projet de recherche. Nos études sont orientées vers la conception de trois classes distinctes de ligands. Une première famille à été conçue sur une charpente benz

APA, Harvard, Vancouver, ISO, and other styles

10

Gulart, Caroline Almeida. "Sensibilidade in vitro e in vivo de isolados de Colletotrichum lindemuthianum (Sacc & Magn.) Briosi & Cav., a fungicidas sistêmicos." Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/4991.

Full text

Abstract:

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The sensitivity of ten isolated of Colletotrichum lindemuthianum the systemic fungicides was evaluated in vitro and in vivo, in experimental design was completely random with three replications. In the study in vitro, it was evaluated the percentage of germination of spores of the fungus when submitted to the benzimidazol fungicides: carbendazin and methyl tiophanate and the estrobilurins: azoxystrobin and pyraclostrobina. The methodology consisted in incorporate the fungicide to the agar at the final concentrations of 0; 0,1; 1,0;

APA, Harvard, Vancouver, ISO, and other styles

11

Dool, Carly Jade 1985. "Pharmacologic inhibition of insulin receptor tyrosine kinase activity has antineoplastic effects similar to alloxan-induced insulin deficiency with less acute metabolic toxicity." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111555.

Full text

Abstract:

Recent population studies provide evidence that individuals with high circulating insulin levels have a poor prognosis and/or increased risk of cancer development; however, laboratory studies concerning the role of insulin in breast cancer biology are sparse. We compared the growth of 4T1 murine breast cancer allografts in control mice, alloxan-induced hypoinsulinemic mice, and mice treated with the insulin/insulin-like growth factor-1 receptor tyrosine kinase inhibitor BMS-536924. Both interventions significantly decreased tumor growth versus control and decreased pathway activation downstrea

APA, Harvard, Vancouver, ISO, and other styles

12

Tsai, Sheng-Chung, and 蔡勝忠. "Synthesis and Antiplatelet Activity of Benzimidazole Analogs of YC-1." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/27595984996809626829.

Full text

Abstract:

博士<br>中國醫藥學院<br>藥物化學研究所<br>88<br>1-Benzyl-3-(5''-hydroxymethyl-2''-furyl)indazole (YC-1) was synthesized in our laboratory a few years ago. Biological studies revealed that YC-1 exhibited antiplatelet activity in vitro through NO-independent activation of soluble guanylate cyclase (sGC). Due to the unique mechanism of action as an antiplatelet agent, 1-benzyl-2-(5''''-hydroxymethyl-5''''-furyl)-benzimidazole (9), a YC-1 bioisostere, was used as a lead compound to pepare a series of its analogs for searching more active potent compound with the same mechanism of antiplatelet activity.

APA, Harvard, Vancouver, ISO, and other styles

13

Chen, Po-Chou, and 陳柏舟. "Synthesis and Antiplatelet Activity of 1-Benzyl-2-(5-methyl-2-furyl)benzimidazole Analogs." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/62490364641322385907.

Full text

Abstract:

碩士<br>中國醫藥大學<br>藥物化學研究所碩士班<br>95<br>As a result of our continuing study aimed at the discovery and development of novel antiplatelet agents, 1-benzyl-2-(5-methyl-2-furyl) benzimidazole (A) was synthesized and evaluated for its antiplatelet activity. The preliminary results of compound A showed good inbibitory effect on collagen, arachidonic acid, U46619-induced platelet aggregation, it can be developed as a new category of drug to treat thrombosis. Encourage by this results, compound A was selected as a lead compound in this article. Two target analogs of benzimidazole were designed, they are

APA, Harvard, Vancouver, ISO, and other styles

14

Esat, Burak. "Nitronyl nitroxides and benzimidazole -3 -oxide -1 -oxyls as building blocks of organic magnetic materials." 2001. https://scholarworks.umass.edu/dissertations/AAI3027196.

Full text

Abstract:

We have synthesized several nitronyl nitroxides (NNs) to study their crystal packing and magnetic properties. These were characterized by ESR spectroscopy, and most by IR and mass spectrometry. Dominant magnetic interactions were studied by magnetic susceptibility studies performed on 2-(3,5-difluorophenyl)-NN and 2-[3,5-bis-(trifluoromethyl)-phenyl)-NN crystals. Structural information was used from X-ray studies to elucidate magnetic interactions present in the NN crystals. The synthesis of the precursors for nitronyl nitroxides was optimized in most of the cases by using triethylamine as the

APA, Harvard, Vancouver, ISO, and other styles

15

Chang, Ying-Ching, and 張孆璟. "Synthesis of Anticacer Bis (benzimidazoles) Library and Benzimidazolyl benzoxazole Related to UK-1." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/8s3bfm.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Ye, Tzuen-Yang, and 葉尊揚. "Copper-Catalysed Aerobic Oxidative Carbocyclization- Ketonization, One-Pot Synthesis of Imidazo[1,2-a]benzimidazole and 1H-pyrrol-1-yl-1H-benzo[d]imidazole-5-carboxylate." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/73013471742307853416.

Full text

Abstract:

碩士<br>國立交通大學<br>應用化學系碩博士班<br>104<br>This thesis is divided into three parts, the first part is copper-catalysed aerobic oxidative carbocyclization- ketonization, one-pot synthesis of imidazo[1,2-a]benzimidazole, the second part is a single copper-catalysed aerobic oxidative carbocyclization- ketonization, one-pot synthesis of 1H-pyrrol-1-yl-1H-benzo [d] imidazole-5-carboxylates, the third part is a synthetic Rosoxacin. Part 1: Two copper metal-catalyzed alkyne-terminal addition to the imine derived from 2-aminobenzimidazole with an aromatic aldehyde formed in an oxygen system and accompanied b

APA, Harvard, Vancouver, ISO, and other styles

17

Kaulage, Mangesh Hanumant. "Structural and Functional Characterization of Quadruplex DNA Structures in Human Acetyl-CoA Carboxylase 1 Gene Promoters and Stabilization of G-quadruplex DNA by Carbazole-benzimidazole Conjugates." Thesis, 2016. https://etd.iisc.ac.in/handle/2005/4375.

Full text

Abstract:

A number of studies have established that DNA targeting is a successful strategy in anticancer therapy. In recent years, however, the focus has shifted from double-stranded DNA to alternative DNA motifs such as G-quadruplex and i-motif structures that are often found in the telomeric and transcriptional regulatory regions of genes in almost all eukaryotic organisms. The mutually exclusive formation of G-quadruplex and i-motif structures by G/C rich sequences, which in turn impact a variety of DNA transactions, suggest that stabilization of such structures by small molecules offer alternative o

APA, Harvard, Vancouver, ISO, and other styles

18

Hsieh, Ying-hsueh, and 謝英雪. "Synthesis and Antiplatelet Activity of 1-Substituted 2-(5'-methyl-2'-furyl)benzimidazoles." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/31104378942560870981.

Full text

Abstract:

碩士<br>中國醫藥學院<br>藥物化學研究所<br>88<br>To further explore the structure-activity relationship of YC-1 analogs in this work, I selected 5-methyl furfural (2) as starting material for condensation with o-phenyldiamine (1), in the precence of cupric acetate, to afford 2-(5´-methyl-2´-furyl) benzimidazole (3). Compound 3 was subsequently reacted with substituted benzyl chlorides to yield the 1-substituted benzl-2- (5´-methyl-2´-furyl)benzimidazoles (4~6). The antiplatelet activity of target compounds 3 and 4 were examined. Both compounds exhibit significant inhibitory effect against AA and co

APA, Harvard, Vancouver, ISO, and other styles

19

廖本原. "(1) Synthetic Studies of Benzimidazoles from Amidoximes (2) Copper-Catalyzed Synthesis of Indoles." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/04716447104067185921.

Full text

Abstract:

碩士<br>國立臺灣師範大學<br>化學系<br>102<br>This thesis covers two separated topics. The first part is the synthesis of N-phenyl hetero-aryl carboxamidoximes with different substituents on the bezene ring. The reaction of the N-phenyl hetero-aryl carboxamidoximes with p-toluenesulfonic anhydride undergoes a direct intramolecular electrophilic aromatic substitution at low temperature, to afford 2-hetero-arylbenzimidazole derivatives. Moreover, we also found that the reaction of arylcarboxamidoximes with different sulfonyl reagents undergo Tiemann rearrangement reaction to afford corresponding of N,N’-disub

APA, Harvard, Vancouver, ISO, and other styles

20

Wang, Chien-Hong, and 王建泓. "Synthesis of benzimidazoles via(1) Copper(I)-catalyzed Buchwald–Hartwig reaction and(2) Electrophilic aromatic substitution reaction." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/44099682207361315382.

Full text

Abstract:

碩士<br>國立臺灣師範大學<br>化學系<br>103<br>2-Aminobenzimidazole derivatives are important nitrogen-containing heterocycles which often were embedded in many biologically active molecules. This thesis focuses on the synthesis of 1-aminobenzimidazole derivatives from benzonitriles. In the first part, a direct approach for the synthesis of 2-(N-alkylamino)benzimidazoles from o-bromobenzonitriles was developed. The reaction of o-bromophenylcyanamides, obtained from o-bromobenzonitriles via Tiemann rearrangement, with various primary and secondary alkylamines employing of copper(I) iodide and 1,10-phenanthrol

APA, Harvard, Vancouver, ISO, and other styles

21

Kuang, Tsai-Chi, and 匡載麒. "Synthesis of 1-substituted benzyl-5(or 6) substituted 2-(5-methyl-2-furyl)benzimidazoles as antiplatelet drugs." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/74358954381439316314.

Full text

Abstract:

碩士<br>中國醫藥大學<br>藥物化學研究所碩士班<br>99<br>In continuing development of novel aniplatelet agents, we had found that 1-benzyl-2-(5-methyl-2-furyl)benzimidazole (1) showed good platelet inhibitory activity. Compound 1 showed good inhibitory effect on the platelet aggregation induced by collagen, arachidonic acid, and U46619. Encouraged by this result, the compound 1 was selected as a lead compound and a series of 1-substituted benzyl-5(or 6)substituted-2-(5-methyl-2-furyl) benzimidazoles derivatives (4-19, 21-36, 42~51) were synthesized in this work. All the synthesized compounds were evaluated for

APA, Harvard, Vancouver, ISO, and other styles

22

Lin, Pei-Jung, and 林佩蓉. "Synthesis and antiplatelet activities of 1-substituted benzyl-5(or/and 6) substituted -2-(5-methyl-2-furyl)benzimidazoles." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/44262398013467540705.

Full text

Abstract:

碩士<br>中國醫藥大學<br>藥物化學研究所碩士班<br>98<br>In continuing study of novel antiplatelet agents, we had found that 1-benzyl-2-(5-methyl-2-furyl) benzimidazole (1) exhibited good antiplatelet activity. Compound 1 showed good inhibitory effect on the platelet aggregation induced by collagen, arachidonic acid, and U46619. Encourage by this result, compound 1 was selected as a lead compound, and a series of 1-substituted benzyl-5(or/and 6) substituted- 2-(5-methyl-2- furyl)benzimidazoles (4~18, 20~34, 36~43, 45~52) were synthesized. All the synthesized compounds were evaluated for their antiplatelet activiti

APA, Harvard, Vancouver, ISO, and other styles

23

Li, Jian-Kuan, and 李建寬. "Synthesis and antiplatelet activities of 1-substituted benzyl-5(or 6 or 5,6 )halo-2-(5-methyl-2-furyl)benzimidazoles." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/7n7a4b.

Full text

Abstract:

碩士<br>中國醫藥大學<br>藥物化學研究所碩士班<br>101<br>In continuing development of novel aniplatelet agents, we had found that 1-benzyl-2-(5-methyl-2-furyl)benzimidazole (1) showed good platelet inhibitory activity. Compound 1 showed good inhibitory effect on the platelet aggregation induced by collagen, arachidonic acid, and U46619. Encouraged by this result, the compound 1 was selected as a lead compound and a series of 1-substituted benzyl-5(or 6 or 5,6)substituted-2-(5-methyl-2-furyl) benzimidazoles derivatives (3-18,19-43) were synthesized in this work. All the synthesized compounds were evaluated for

APA, Harvard, Vancouver, ISO, and other styles

24

Lin, Shao-Hsuan, and 林少軒. "Self-Assembly, Structures and Properties of Metal-Organic Frameworks from 1,3,5-tris(benzimidazoyl-1-ylmethyl)-2,4,6-trimethylbenzene and Transition Metal Ions." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/69939641828296748559.

Full text

Abstract:

碩士<br>國立臺灣師範大學<br>化學系<br>99<br>In this thesis, metal–organic coordination frameworks were prepared by reacting a ligand, 1,3,5-tris(benzimidazoyl-1-ylmethyl)-2,4,6-trimethylbenzene (TBzIm), with transition metal ions (ZnII, CoII, MnII, and NiII) and different carboxylic acids under hydrothermal conditions. We report eight compounds in this study, 4(H3O)+[Zn8(TBzIm)2(btc)4Cl8]•4H2O (1), [Zn12(TBzIm)2(bdc)4Cl16]•3H2O (2), [Co4(TBzIm)4(Hbtc)4] (3), [Co2(TBzIm)2(bdc)2]•3H2O (4), [Mn5Cl10(TBzIm)4]•1acetone (5), [Co2(Fum)2(TBzIm)2]n (6), [Ni2(Fum)2(TBzIm)2]n (7), and [Co12(TBzIm)4(D-Cam)12] (8). A

APA, Harvard, Vancouver, ISO, and other styles

25

Yao, Po-Hsin, and 姚伯昕. "1.Diversity-Oriented Synthesis of Coumarin-Linked Benzimidazoles via a One-Pot, Three-Step, Intramolecular Knoevenagal Cyclization 2.Multicomponent Reaction Synthesis of 2-aza-7-arylpyrrolizidine alkaloid Derivatives." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/5p73u6.

Full text

Abstract:

碩士<br>國立交通大學<br>應用化學系碩博士班<br>105<br>First part:One-pot, three step synthesis of 3-(1-propyl-1H- benzo[d]imidazol-2-yl)-2H-chromen-2-one, using 2-cyano-N-(2-(propylamino)phenyl)acetamide compound 11 under p-toluene sulfonic acid catalyst to undergo intramolecular cyclization to form 2-(1-propyl-1H-benzo[d]imidazol-2-yl)acetonitrile compound 12, then add proper triethylamine to undergo Knoevenagel condensation reaction to get intermediate 14, and finally add 1N HCl to provide compound 15. Second part: Compounds 12 obtained in the first part of the study can further synthesize polycyclic structur

APA, Harvard, Vancouver, ISO, and other styles

26

林淑芬. "（（Ⅰ）Microwave-Assisted Liquid Phase Parallel Synthesis of Bis(benzimidazoles) Library which Has Anticancer Activity Analogue to UK-1（Ⅱ）Microwave-Assisted Liquid Phase Syntehsie of Quinoxalinone Library via Ugi Four-Component Condensation（Ⅲ）Solut." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/12025886230606867834.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Lin, Yi-Feng, and 林義峰. "Part Ⅰ Synthesis and Photochemistry of a series of radical pair precursors contain 1-toluene sulphonyl benzimidazoles and their derivatives Part Ⅱ Synthesis of (4,4´-dicarboxylate-2,2´-bipyridyl) ruthenium complexes applied in the solar cell." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/45209660368849627531.

Full text

Abstract:

碩士<br>國立交通大學<br>應用化學系所<br>93<br>The major part of this thesis is about the syntheses and EPR studies of a series of radical pair precursors (55, 56 and 57) which contain 1-toluene sulphonyl benzimidazoles as the key components. The photolysis (230-325 nm) of 55 at 77 K in a MTHF matrix gave EPR signals characteristic of a randomly oriented triplet radical pair and its zero-field splitting parameters are determined to be |D/hc| = 0.0144 cm-1 and |E/hc| = 0.0020 cm-1, respectively. Furthermore, the photolysis of 55 in the presence of MNP in CDCl3 at room temperature gave not only the Photo-Fries

APA, Harvard, Vancouver, ISO, and other styles

28

Lamont, F. R., D. C. Tomlinson, Patricia A. Cooper, Steven D. Shnyder, J. D. Chester, and M. A. Knowles. "Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo." 2011. http://hdl.handle.net/10454/6061.

Full text

Abstract:

BACKGROUND: Activating mutations of FGFR3 are frequently identified in superficial urothelial carcinoma (UC) and increased expression of FGFR1 and FGFR3 are common in both superficial and invasive UC. METHODS: The effects of inhibition of receptor activity by three small molecule inhibitors (PD173074, TKI-258 and SU5402) were investigated in a panel of bladder tumour cell lines with known FGFR expression levels and FGFR3 mutation status. RESULTS: All inhibitors prevented activation of FGFR3, and inhibited downstream MAPK pathway signalling. Response was related to FGFR3 and/or FGFR1 expression

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!