Relevant bibliographies by topics / Benzofuranones

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Benzofuranones'

Author: Grafiati
Published: 4 June 2021
Last updated: 22 February 2023

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Journal articles on the topic "Benzofuranones"

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Qiu, Renhua, Nobuaki Kambe, Zhi Tang, Zhou Tong, and Shuang-Feng Yin. "Recent Advances on Benzofuranones: Synthesis and Transformation via C–H Functionalization." Synthesis 53, no. 18 (2021): 3193–210. http://dx.doi.org/10.1055/a-1405-5761.

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AbstractThe benzofuranone structure is important in many fields, such as natural products, pharmaceuticals, building blocks, antioxidants, and dyes. The efficient synthesis and transformation of benzofuranones have attracted great attention in organic synthesis. They can be synthesized by the Friedel–Crafts reaction and intramolecular dehydration ring-closing and transition-metal-catalyzed reactions, among others. Their direct utilization in the preparation of other functional molecules further enhance their application. Due to their low pK a value and easy enolization, the transformation of b
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García-Lacuna, Jorge, Maialen Alonso, Gema Domínguez, and Javier Pérez Castells. "Study of the Pauson–Khand reaction in flow over alkynylphenyl vinyl ethers: towards the synthesis of tricyclic multisubstituted benzofurans." RSC Advances 12, no. 12 (2022): 7313–17. http://dx.doi.org/10.1039/d2ra01062c.

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Wang, Mo, Xiao Zhang, Zheng Ling, Zhenfeng Zhang, and Wanbin Zhang. "Direct enantioselective C-acylation for the construction of a quaternary stereocenter catalyzed by a chiral bicyclic imidazole." Chemical Communications 53, no. 8 (2017): 1381–84. http://dx.doi.org/10.1039/c6cc09451a.

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Speisky, Hernán, María Fernanda Arias-Santé, and Jocelyn Fuentes. "Oxidation of Quercetin and Kaempferol Markedly Amplifies Their Antioxidant, Cytoprotective, and Anti-Inflammatory Properties." Antioxidants 12, no. 1 (2023): 155. http://dx.doi.org/10.3390/antiox12010155.

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The contention that flavonoids’ oxidation would necessarily lead to a loss of their antioxidant properties was recently challenged by the demonstration that quercetin oxidation leads to the formation of 2-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxy-3(2H)-benzofuranone (Que-BZF), a metabolite whose antioxidant potency was notably higher than that of its precursor. Here, we compared and expanded the former observation to that of the quercetin analogue kaempferol. Oxidation of kaempferol led to the formation of a mixture of metabolites that included the 2-(4-hydroxybenzoyl)-2,4,6-trihydroxy-3(2H)-ben
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Xu, Kunhua, Wenming Chen, Xu Chen, Biao Wang, Jun Huang, and Xu Tian. "Organocatalytic asymmetric Friedel–Crafts alkylation/hemiketalization/lactonization cascade reactions: highly enantioselective synthesis of furo[2,3-b]benzofuranones." Organic Chemistry Frontiers 7, no. 13 (2020): 1679–84. http://dx.doi.org/10.1039/d0qo00475h.

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A highly diastereo- and enantioselective organocatalytic Friedel–Crafts alkylation/hemiketalization/lactonization cascade reaction generating furo[2,3-b]benzofuranones in good to excellent yields with high stereoselectivities.
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Peng, Xueke, Zhiye Hu, Jing Zhang та ін. "Construction of benzofuranone library via a metal-free, one-pot intermolecular condensation, and their application as efficient estrogen receptor β modulators". Chemical Communications 55, № 97 (2019): 14570–73. http://dx.doi.org/10.1039/c9cc05756k.

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Facile synthesis of benzofuranones as efficient estrogen receptor β modulators was achieved through a metal-free, one-pot intermolecular condensation between α-hydroxy aryl ketones and resorcinol derivatives.
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Zhang, Xiaojie, and Christopher M. Beaudry. "Regioselective Synthesis of Benzofuranones and Benzofurans." Journal of Organic Chemistry 86, no. 9 (2021): 6931–36. http://dx.doi.org/10.1021/acs.joc.1c00341.

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Li, Yao, Xin Li, and Jin-Pei Cheng. "Catalytic Asymmetric Synthesis of Chiral Benzofuranones." Advanced Synthesis & Catalysis 356, no. 6 (2014): 1172–98. http://dx.doi.org/10.1002/adsc.201301038.

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Hu, Chen, Gang Hong, Pradip D. Nahide, et al. "C(sp3)–H hydroxylation of fluorenes, oxindoles and benzofuranones with a Mg(NO3)2–HP(O)Ph2 oxidation system." Organic Chemistry Frontiers 6, no. 17 (2019): 3167–71. http://dx.doi.org/10.1039/c9qo00778d.

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A novel oxidation system in which magnesium nitrate is used as an oxidant in the presence of diphenylphosphine oxide permits the C(sp<sup>3</sup>)–H hydroxylation of fluorenes, oxindoles, and benzofuranones.
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Huang, Zhusheng, Xiuqin Yang, Fulai Yang, Tao Lu та Qingfa Zhou. "Phosphine-Catalyzed Domino β/γ-Additions of Benzofuranones with Allenoates: A Method for Unsymmetrical 3,3-Disubstituted Benzofuranones". Organic Letters 19, № 13 (2017): 3524–27. http://dx.doi.org/10.1021/acs.orglett.7b01482.

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Dissertations / Theses on the topic "Benzofuranones"

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Bahhaj, Fatima El. "Nanosondes épigénétiques." Thesis, Poitiers, 2014. http://www.theses.fr/2014POIT2289/document.

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Les cibles épigénétiques telles que les histones désacétylases (HDAC) sont étudiées comme nouveaux traitements anticancéreux, leur fonctionnement anormal étant associée aux processus cancéreux. De nombreux inhibiteurs de ces enzymes sont apparus tel que le SAHA ou le CI-994. Notre laboratoire a développé un nouvel analogue de la trichostatine A appelé NODH. Malgré leur activité anticancéreuse in vitro prometteuse, ces inhibiteurs souffrent de leur manque de solubilité, d'effets toxiques et de leur rapide métabolisation par l'organisme. Afin de pallier ces limitations, ces iHDAC peuvent être co
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Hills, Ivory Derrick 1977. "Catalytic enantioselective synthesis of oxindoles and benzofuranones bearing a quaternary stereocenter and reactions of palladium bisphosphine complexes relevant to catalytic C-C bond formation." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/28699.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2004.<br>Includes bibliographical references.<br>In Part I the development of a new method for the construction of oxindoles and benzofuranones bearing quaternary stereocenters is discussed. A planar-chiral PPY derivative catalyzes the O-to-C acyl group migration (Black rearrangement) in a highly efficient and enantioselective manner. The utility of this method is further demonstrated by the formal total synthesis of the natural product aplysin. In Part II reactivity of bisphosphine palladium-complexes is discussed. It
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Mougin, Catherine. "Synthèse et évaluation des propriétés de nouveaux agents modérateurs de la polymérisation radicalaire. Nouvelles préparations d'hétérocycles azotés." Phd thesis, Ecole Polytechnique X, 2006. http://pastel.archives-ouvertes.fr/pastel-00001979.

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Cette thèse se divise en trois parties. La première concerne le développement d'une nouvelle voie d'accès à des hétérocycles azotés. Cette synthèse est basée sur deux étapes: l'addition radicalaire d'un xanthate, portant une fonction 1,2-dione, sur diverses oléfines suivie de sa condensation sur une diamine. Cette étude a permis de préparer des composés présentant un intérêt biologique certain tels que des pyrazines. De plus, une nouvelle méthodologie permettant l'accès à des structures imidazoles a été mise en évidence. La seconde partie a été consacrée à la préparation d'un support soluble à
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Brant, Antonio Jedson Caldeira. "Flavonóides, cumarinas e benzofuranos como marcadores quimiotaxonômicos em Asteraceae." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/46/46135/tde-02102008-085120/.

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Este trabalho descreve as ocorrências naturais de flavonóides, cumarinas e benzofuranos na família de plantas, Asteraceae / Compositae. Tem como objetivo principal classificar os referidos metabólitos secundários como possíveis marcadores quimiotaxonômicos da família bem como fazer previsões de suas ocorrências naquela. Para sua realização, foi montado um banco de dados de ocorrências desses produtos naturais a partir da literatura especializada. Os números de ocorrências das três classes químicas (flavonóides, 4369;cumarinas, 961; benzofuranos, 628) foram avaliados através de programas comput
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Hessamian-Alinejad, Anahita. "Synthese von spiro-Benzofuranonen als Inhibitoren für die Peptidyl-Prolyl-cis/trans-Isomerasen der hPin1." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=96635754X.

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Silva, Eliezer Pereira. "Novos alquenil benzofuranos e perfil de ácidos graxos presentes nas sementes e folhas de Tapirira guianansis(Anacardiaceae)." reponame:Repositório Institucional da UFBA, 2011. http://www.repositorio.ufba.br/ri/handle/ri/10804.

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77 f.<br>Submitted by Ana Hilda Fonseca (anahilda@ufba.br) on 2013-04-11T16:04:37Z No. of bitstreams: 1 Flor de tricô.docx: 411814 bytes, checksum: d1a4ae77e444ad8ff1fca87eb3a1c5c0 (MD5)<br>Rejected by Ana Hilda Fonseca(anahilda@ufba.br), reason: ficheiro on 2013-05-10T16:32:57Z (GMT)<br>Submitted by Ana Hilda Fonseca (anahilda@ufba.br) on 2013-05-10T16:43:14Z No. of bitstreams: 1 Dissertação Eliezer P Silva.pdf: 1502056 bytes, checksum: cb8a09e51fa693a4aebb9e1f01350220 (MD5)<br>Approved for entry into archive by Ana Hilda Fonseca(anahilda@ufba.br) on 2013-05-10T16:46:24Z (GMT) No. of bitstrea
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Bombonato, Fernanda Irene. "Estudos visando à síntese do jungianol e a construção de anéis benzofurânicos utilizando TTN." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/46/46135/tde-04092007-145143/.

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Neste trabalho descrevemos os estudos visando à síntese do jungianol e a construção de anéis benzofurânicos. Em ambos os casos, a etapa chave da seqüência sintética é a reação de contração de anel mediada por tálio(III). O jungianol é um sesquiterpeno fenólico que foi isolado por Bohlmann et al., em 1977, da espécie Jungia malvaefolia. A etapa chave da síntese seria a reação do 1,2-diidro-5-metóxi-1,6-dimetilnaftaleno (intermediário-chave) com trinitrato de tálio (TTN), para dar origem ao esqueleto indânico presente no jungianol. Duas abordagens sintéticas foram utilizadas na tentativa de pr
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8

Ahmad, Anees. "Exploring the iodine(III)-mediated ring contraction: new substrates, novel conditions and asymmetric reactions." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/46/46136/tde-29092015-145020/.

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In the first section this thesis includes the reactivity of various oxygen-containing benzofused cyclic alkenes with HTIB (Hydroxy(tosyloxy)iodobenzene). Instead of getting ring contraction products, 2H-chromene resulted in 4H-chromenes together with trans-addition products. Only cis-addition products were isolated from 4-methyl-2H-chromene. Ring contraction was observed in dihydrobenzoxepines and 2,2-dimethyl-2H-chromenes giving functionalized chromanes and benzofurans, respectively. In the second part, the ring contraction of 1,2-dihydronaphthalenes using HTIB was expanded to substrates be
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López, Muñoz Laura. "Homology modeling and structural analysis of the antipsychotic drugs receptorome." Doctoral thesis, Universitat Pompeu Fabra, 2010. http://hdl.handle.net/10803/7228.

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Classically it was assumed that the compounds with therapeutic effect exert their action interacting with a single receptor. Nowadays it is widely recognized that the pharmacological effect of most drugs is more complex and involves a set of receptors, some associated to their positive effects and some others to the side effects and toxicity. Antipsychotic drugs are an example of effective compounds characterized by a complex pharmacological profile binding to several receptors (mainly G protein-coupled-receptors, GPCR). In this work we will present a detailed study of known antipsychotic drug
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PUGLISI, ANTONIO. "Quinones in asymmetric arylation and biaryl coupling." Doctoral thesis, 2017. http://hdl.handle.net/11573/1062383.

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Quinones are widespread compounds in nature, where they play key roles due to their biological activity. Quinones have proven their usefulness in the field of synthetic chemistry, being excellent oxidants and electrophiles. In this thesis work, two example of efficient exploitment of quinones as electrophiles are presented. In one case, an asymmetric organocatalyzed biaryl couling is presented, a reaction which proceeds with the addition of a nucleophilic naphthol to a substituted electrophilic quinone, followed by rearomatization of the quinone. The reaction is catalyzed by Cinchona alkaloids
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Book chapters on the topic "Benzofuranones"

1

"Benzofuranones." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186992.ch5.

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