Academic literature on the topic 'Bifunctional compound'

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Journal articles on the topic "Bifunctional compound"

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Zaichenko, N. L., A. I. Shienok, L. S. Koltsova, et al. "Bifunctional photosensitive compound for optical processors." physica status solidi (c) 8, no. 9 (2011): 2746–48. http://dx.doi.org/10.1002/pssc.201084039.

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Chen, Katherine, Alice Jih, Sarah T. Kavaler, et al. "Dual actions of a novel bifunctional compound to lower glucose in mice with diet-induced insulin resistance." American Journal of Physiology-Endocrinology and Metabolism 309, no. 3 (2015): E293—E301. http://dx.doi.org/10.1152/ajpendo.00045.2015.

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Docosahexaenoic acid (DHA 22:6n-3) and salicylate are both known to exert anti-inflammatory effects. This study investigated the effects of a novel bifunctional drug compound consisting of DHA and salicylate linked together by a small molecule that is stable in plasma but hydrolyzed in the cytoplasm. The components of the bifunctional compound acted synergistically to reduce inflammation mediated via nuclear factor κB in cultured macrophages. Notably, oral administration of the bifunctional compound acted in two distinct ways to mitigate hyperglycemia in high-fat diet-induced insulin resistanc
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Yokochi, Hirogi, Rikito Takashima, Daisuke Aoki, and Hideyuki Otsuka. "Using the dynamic behavior of macrocyclic monomers with a bis(hindered amino)disulfide linker for the preparation of end-functionalized polymers." Polymer Chemistry 11, no. 21 (2020): 3557–63. http://dx.doi.org/10.1039/d0py00366b.

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End-functionalized polymers were synthesized by simply heating a mixture of a macrocyclic compound with one bis(2,2,6,6-tetramethylpiperidin-1-yl)disulfide (BiTEMPS) moiety and bifunctional acyclic BiTEMPS compounds as sources of repeat units and terminal groups, respectively.
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El-Gazzar, Marwa G., and Hala M. Aly. "Anticancer Evaluation and Docking Study of New Bifunctional Phthalazine Derivatives." Current Organic Synthesis 15, no. 3 (2018): 414–22. http://dx.doi.org/10.2174/2211556006666170927155809.

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Aims and Objective: A series of novel phthalazine derivatives was synthesized with versatile, readily accessible electrophilic and nucleophilic reagents. The newly synthesized compounds were confirmed by the results of spectroscopic measurements. Hence, their potential clinical application investigated in particular for cancer treatment. Materials and Methods: The newly synthesized compounds were characterized by spectroscopic measurements and were tested for their in vitro anticancer activity by MTT assay against human liver cancer cell line. Docking study of all the synthesized compounds was
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Ren, Tan, Guisheng Zhang, and Dexi Liu. "Synthesis of bifunctional cationic compound for gene delivery." Tetrahedron Letters 42, no. 6 (2001): 1007–10. http://dx.doi.org/10.1016/s0040-4039(00)02221-8.

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Choi, Dong Hoon, Sang Joon Oh, Hyo Bok Cha, and Joon Youl Lee. "Photochemically bifunctional epoxy compound containing a chalcone moiety." European Polymer Journal 37, no. 10 (2001): 1951–59. http://dx.doi.org/10.1016/s0014-3057(01)00102-1.

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Shiyonok, A. I., N. L. Zaichenko, L. S. Kol"tsova, and V. S. Marevtsev. "Photochemically bifunctional compound from the class of spironaphthooxazines." Russian Chemical Bulletin 52, no. 10 (2003): 2294–95. http://dx.doi.org/10.1023/b:rucb.0000011898.89321.85.

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Souard, Florence, Edwige Nicolle, Delphine Cressend, Alexis Valentin, and Ahcène Boumendjel. "Two in one: bifunctional derivatives of trolox acting as antimalarial and antioxidant agents." Future Medicinal Chemistry 12, no. 20 (2020): 1845–54. http://dx.doi.org/10.4155/fmc-2020-0106.

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Background: The aim of the present work was to set-up compounds that are able to act simultaneously as antimalarial and antioxidants. Trolox, a known antioxidant was chosen as a core structure to ensure the antioxidant activity and contribute to antiplasmodial effect. Results: Ten compounds were prepared in one step and evaluated on chloroquino-sensitive (3D7) and chloroquino-resistant (FcB1) strains of Plasmodium falciparum. The most active compound (3d) shows antiplasmodial activity in the range of chloroquine against chloroquino-sensitive and chloroquino-resistant P. falciparum strain. The
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Schulte, Marcus, and François P. Gabbaï. "Synthesis of heteronuclear bifunctional Lewis acids by transmetalation of 1,8-bis(trimethylstannyl)naphthalene with BCl3." Canadian Journal of Chemistry 80, no. 10 (2002): 1308–12. http://dx.doi.org/10.1139/v02-177.

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Reaction of 1,8-bis(trimethylstannyl)naphthalene (1) with an excess of BCl3 at –78°, followed by warming to 0°C, results in the exclusive formation of the novel bifunctional Lewis acid 1-(chlorodimethylstannyl)-8-(dichloroboryl)naphthalene (2), a compound in which a boryl and a stannyl moiety coexist at the peri-positions of a naphthalene core. At elevated temperature compound 2 undergoes a chloride–methyl exchange, which affords 1-(dichloromethylstannyl)-8-(chloromethylboryl)naphthalene (3). Compounds 2 and 3 have been characterized by multi-nuclear NMR spectroscopy. The single crystal X-ray
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Starnowska-Sokół, Joanna. "A hybrid for pain, i.e. bifunctional analgesics in neuropathy." BÓL 21, no. 4 (2021): 17–24. http://dx.doi.org/10.5604/01.3001.0014.8073.

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The need of developing new neuropathic pain therapies results from limited potency of currently available treatments, which is underlain by low efficacy of conventional analgesics, complex etiology and pathogenesis of neuropathy, diversity of its symptoms, as well as heightened side effects risk that accompanies the polypharmaceutical strategy, employed commonly to improve the therapeutic outcomes. Designing hybrid compounds, i.e. multimodal molecules that present the affinity to more than one receptor target, offers a promising perspective in this context. The multimodal approach allows to in
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Dissertations / Theses on the topic "Bifunctional compound"

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Peng, Chen. "Synthesis of very-long-chain bifunctional and isotope-labeled compounds for biochemical investigations into novel compounds in plant cuticular waxes." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43752.

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Plant cuticles are the interface for plant-environment interactions, and the first barrier protecting plants from environmental stresses such as water loss and pathogens. Structurally, the cuticle consists of a hydrophobic polymer lattice, cutin, and cuticular waxes deposited inside and outside cutin. The major components of the cuticular waxes are aliphatics derived from very-long-chain (VLC) fatty acids, such as alkanes and aldehydes. Besides compounds with primary functionalities, some compounds with two or more functional groups have also been identified in cuticular waxes. However, only l
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Avci, Gulden. "Analysis Of Phenol Oxidation Products By Scytalidium Thermophilum Bifunctional Catalase/phenol Oxidase (catpo)." Phd thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613770/index.pdf.

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This thesis was aimed to analyze phenol oxidation by the bifunctional catalase/phenol oxidase of the thermophilic fungus Scytalidium thermophilum. Several reactive oxygen species (ROS) are continuously produced in fungi under oxidative stress. Depending on the nature of the ROS species, some are highly toxic and are rapidly detoxified by various cellular enzymatic mechanisms, including the production of catalase. S. thermophilum produces a novel bifunctional catalase-phenol oxidase (CATPO) which is capable of oxidizing phenolics in the absence of hydrogen peroxide. Phenol oxidases convert phen
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CAMPISTRON, GUILMET IRENE. "La reaction de metathese : synthese de molecules modeles et de diesters polydieniques, degradation controlee des polydienes." Le Mans, 1987. http://www.theses.fr/1987LEMA1021.

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Amelioration des processus de synthese des composes modeles des polydienes et d'oligomeres alpha , omega -bifonctionnels par reaction de cometatheses du cyclooctadiene-1,5 avec l'octene-4, le methyl-4 octene-4, l'hexadiene-1,5 et l'hexene-3 dioate de dimethyle
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Razmutė-Razmė, Inga. "Vibrational spectroscopic studies on the structure and interaction with solution components of bifunctional organic compounds adsorbed at metal electrodes." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2009. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2009~D_20091215_091605-81688.

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The indole and phenole rings comprise the main part of tryptophan and tyrosine side chains in proteins and play an important role in the stabilization of tertiary structure, interaction with active centers in biomolecules, and electron transfer phenomena. To get better insight into the interactions of these functional groups, the artificial monomolecular structures have been constructed from the synthesized bifuncional compounds with thiol and indole or phenole ring functional groups able to form self-assembled monolayers on gold, silver and copper electrodes. Properties of these monolayers we
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Denis, Alexis. "Fonctionnalisations selectives a l'aide des complexes du palladium : synthese de composes d'interet biologiques, cyclopropanes vinyliques, aryl-3 oxazolidinones-2 (inhibiteurs potentiels de la monoamine oxydase)." Paris 6, 1987. http://www.theses.fr/1987PA066335.

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Ce travail porte sur l'utilisation du palladium (o) pour la synthese de molecules d'interet biologique. En premier lieu, on decrit la synthese stereoselective de cyclopropanes vinyliques et de pyrethrinoides. Dans un second temps, on etudie l'echange acetate phenol et l'amination de derives allyliques fibonctionnels. Enfin, on presente la synthese d'aryl-3 dihydroxy-5,5 oxazolidones-2 erythro et threo et etudie leur utilisation en tant qu'inhibiteur d'enzyme monoamine oxidase
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Vasalatiy, Olga V. "Labeling of protein surfaces with bifunctional PARACEST agents /." 2007. http://proquest.umi.com/pqdweb?did=1296102451&sid=2&Fmt=2&clientId=10361&RQT=309&VName=PQD.

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Shaw, Megan Lorraine. "Bifunctional phosphines : synthesis and evaluation in catalysis." Thesis, 2012. http://hdl.handle.net/10210/7261.

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M.Sc.<br>This study focused on the synthesis and evaluation of phosphine ligands with multiple functional ities. Polar ligands suitable for use in homogeneous catalysis in aqueous/organic systems were synthesised, as were ligands incorporating a boron atom in an intramolecular Lewis acid-Lewis base interaction with the phosphorus atom. A malonate moiety was readily incorporated into a phosphorus starting material, and derivatives were obtained by reduction of the ester groups. The polar diol products were reacted with 1,4-butanesultone which made them water soluble and thus ideal for biphasic
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Chang, Chun-Hsiung, and 張俊雄. "Development of New Synthetic Method of Acene Compounds and It's Application in Bifunctional Acene Systems." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/72924163540198099190.

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碩士<br>國立臺灣師範大學<br>化學系<br>98<br>In the past decade, acenes have played an important role in the research of organic materials, owing to their excellent photoelectric properties. However, the stability and solubility problems of acenes compounds are formidable roadblocks to their future applications. The goal of this thesis is to develop simple and mild synthetic reaction to synthesis of acene skeletons. Previously, we developed an iterative elongation protocol consisted of Wittig olefination and Knoevenagel condensation. We hereby describe have two new synthetic method based on our publishe
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Siwek, Mariana [Verfasser]. "Isolation of organic selenium compounds from Antarctic krill after enzymatic hydrolysis and bifunctional chromatography / vorgelegt von Mariana Siwek." 2008. http://d-nb.info/988979012/34.

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Books on the topic "Bifunctional compound"

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Bifunctional compounds. Oxford University Press, 1994.

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Ikariya, Takao. Bifunctional Molecular Catalysis. Springer-Verlag Berlin Heidelberg, 2011.

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Ikariya, Takao, and Masakatsu Shibasaki. Bifunctional Molecular Catalysis. Springer, 2011.

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Ikariya, Takao, and Masakatsu Shibasaki. Bifunctional Molecular Catalysis. Springer, 2013.

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Book chapters on the topic "Bifunctional compound"

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Li, Hu, Xiao Kong, Zhen Fang, and Richard L. Smith. "Fundamentals of Bifunctional Catalysis for Transforming Biomass-Related Compounds into Chemicals and Biofuels." In Production of Biofuels and Chemicals with Bifunctional Catalysts. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-5137-1_1.

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Reyman, Dolores, and Cristina Díaz-Oliva. "Excited-State Double Hydrogen Bonding Induced by Charge Transfer in Isomeric Bifunctional Azaaromatic Compounds." In Hydrogen Bonding and Transfer in the Excited State. John Wiley & Sons, Ltd, 2010. http://dx.doi.org/10.1002/9780470669143.ch30.

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Kimura, Shunsaku, and Yukio Imanishi. "Bifunctional peptides composed of helical segment and sugar, crown ether, or cyclic peptide, and the function regulation." In Peptides. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2264-1_137.

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Kyrychenko, Alexander, and Jacek Waluk. "From the Gas Phase to a Lipid Membrane Environment: DFT and MD Simulations of Structure and Dynamics of Hydrogen-Bonded Solvates of Bifunctional Heteroazaaromatic Compounds." In Challenges and Advances in Computational Chemistry and Physics. Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-3034-4_2.

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Sato, N. "From a 1,2-Bifunctional Compound and Ammonia or Ammonium." In Six-Membered Hetarenes with Two Identical Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-016-00923.

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Sato, N. "From a 1,2-Bifunctional Compound and Ammonia or Ammonium." In Six-Membered Hetarenes with Two Identical Heteroatoms. Georg Thieme Verlag KG, 2011. http://dx.doi.org/10.1055/sos-sd-116-00432.

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Sartori, G., and R. Maggi. "By Reaction with Bifunctional Compounds." In Four Carbon-Heteroatom Bonds. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-018-00834.

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Phillips, Gary, and Michael Salmon. "Bifunctional Compounds for the Treatment of COPD." In Annual Reports in Medicinal Chemistry Volume 47. Elsevier, 2012. http://dx.doi.org/10.1016/b978-0-12-396492-2.00014-x.

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Török, Béla, Árpád Molnár, Károly Borszéky, Enikö Tóth-Kádár, and Imre Bakonyi. "Selective catalytic hydrogenation of bifunctional compounds over amorphous nickel alloys." In Studies in Surface Science and Catalysis. Elsevier, 1993. http://dx.doi.org/10.1016/s0167-2991(08)63318-2.

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Amitai, G., R. Adani, I. Rabinovitz, et al. "Bifunctional compounds eliciting both anti-inflammatory and cholinergic activity as potential drugs for CNS disorders." In Cholinergic Mechanisms. CRC Press, 2004. http://dx.doi.org/10.3109/9780203493878-42.

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Conference papers on the topic "Bifunctional compound"

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Saraswati, Teguh Endah, Oktaviana Dewi Indah Prasiwi, Abu Masykur, and Miftahul Anwar. "Bifunctional catalyst of graphite-encapsulated iron compound nanoparticle for magnetic carbon nanotubes growth by chemical vapor deposition." In INTERNATIONAL CONFERENCE ON ENGINEERING, SCIENCE AND NANOTECHNOLOGY 2016 (ICESNANO 2016). Author(s), 2017. http://dx.doi.org/10.1063/1.4968282.

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Dekamin, Mohammad, M. Reza Naimi-Jamal, Mehdi Farahmand, and Zahra Karimi. "Highly turnover number cyanosilylation of carbonyl compounds catalyzed by tetraethylammonium 2- (hydroxycarbamoyl)benzoate as a bifunctional organocatalyst: The role of hydrogen bonding." In The 13th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00194.

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Reports on the topic "Bifunctional compound"

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Essigmann, John M., and Robert G. Croy. Development of Novel Bifunctional Compounds That Induce Apoptosis in Prostate Cancer Cells. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada502889.

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Essigmann, John M. Development of Novel Bifunctional Compounds that Induce Apoptosis in Prostate Cancer Cells. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada437129.

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Essigmann, John M. Development of Novel Bifunctional Compounds that Induce Apoptosis in Prostate Cancer Cells. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada454067.

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Essigmann, John M. Development of Novel Bifunctional Compounds that Induce Apoptosis in Prostate Cancer Cells. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada468546.

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Essigmann, John M. Development of Novel Bifunctional Compounds That Induce Apoptosis in Prostate Cancer Cells. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada425127.

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Essigmann, John M., and Robert G. Croy. Development of Novel Bifunctional Compounds that Induce Apoptosis in Prostate Cancer Cells. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada481546.

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