Relevant bibliographies by topics / Biliary tract dysfunction

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  2. Dissertations / Theses
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  4. Conference papers

Academic literature on the topic 'Biliary tract dysfunction'

Author: Grafiati
Published: 5 June 2025
Last updated: 16 July 2025

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Journal articles on the topic "Biliary tract dysfunction"

1

Toouli, James. "Biliary tract motor dysfunction." Baillière's Clinical Gastroenterology 5, no. 2 (1991): 409–30. http://dx.doi.org/10.1016/0950-3528(91)90035-y.

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Shulpekova, Yu O., I. R. Popova, and V. M. Nechaev. "Functional Disorders of the Biliary Tract and Cholelithiasis: Analysis of a Possible Relationship." Russian Journal of Gastroenterology, Hepatology, Coloproctology 34, no. 4 (2024): 94–103. http://dx.doi.org/10.22416/1382-4376-2024-34-4-94-103.

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Aim: Diagnostic criteria for functional disorders of the biliary tract are presented in the materials of the Rome IV consensus, as well as expert councils of Russian and foreign specialists. Episodes of functional biliary pain are caused by a violation of bile outflow through the cystic duct and sphincter of Oddi. It has been suggested that there is a “biliary continuum” in which in some patients’ biliary dysfunction is transformed into cholelithiasis. Key points. Lithogenic bile is considered as the pathophysiological basis for the development of biliary dyskinesia and cholelithiasis. Lithogenic bile provokes inflammation of low grades in the mucous membrane of the biliary tract, decreased contractility of the gallbladder and impaired relaxation of the biliary sphincters, impaired physiological response to cholecystokinin. Changes in motility of the biliary tract may be associated with the influence of hydrophobic bile salts and impaired eicosanoid metabolism. Hyperplasia of the epithelium and muscle layer, hypersecretion of mucin and cholesterol precipitation further impair the outflow of bile. Experimental data and some clinical observations indicate the possibility of transformation of biliary dysfunction into cholelithiasis. Dysfunction of the sphincter of Oddi is one of the possible consequences of cholecystectomy and, in fact, acts as a variant of postcholecystectomy syndrome. The basis for the treatment of biliary dysfunctions are antispasmodics of different classes, which can be combined with ursodeoxycholic acid. The biliary tract-selective antispasmodic hymecromone has shown high effectiveness in relieving biliary pain, which also has a moderate choleretic effect and the ability to prevent the crystallization of cholesterol in bile and can be used both for functional diseases and for cholelithiasis. The domestic drug hymecromone “Odecromone” entered the pharmaceutical market. Conclusion. There is no doubt that the relevance of further study of the patterns of development of biliary dysfunctions and GI is obvious. The study of this problem will contribute to the development of effective preventive approaches, including in the field of nutraceuticals.
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Zakharova, I. N., I. V. Berezhnaya, and S. V. Shishkina. "Chronic constipation combined with biliary tract dysfunction in children: comorbidity or clinical regularity?" Medical Council, no. 17 (November 24, 2019): 130–36. http://dx.doi.org/10.21518/2079-701x-2019-17-130-136.

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Functional disorders of the gastrointestinal tract (GIT) are a common problem in children. The Roman IV criteria adopted in 2016, devoted to the problem of constipation and biliary tract dysfunction in children are developed in accordance with age and are idendoitified by the letter code. This article presents data on the correspondence of the Roman IV criteria and ICD-10 in the combined problem of constipation and biliary tract dysfunction in children. The development of upper gastrointestinal tract pathology caused by increased intracavitary pressure associated with impaired colon motility (chronic constipation) is natural during a prolonged course of chronic constipation. The study based on a specially designed questionnaire in Russia showed that an average of 54% of children in different age groups suffer from chronic constipation, that is, almost every second child. Studies showed that the frequency of biliary tract dysfunction in children with chronic constipation accounts for 42.3 to 100% cases. The survey that we conducted among pediatricians showed that a quarter of doctors found it difficult to establish diagnosis, and 41% of pediatricians struggled with prescribing therapy for persistent constipation in children, especially constipation combined with motor-tonic dysfunction of the colon in children with biliary tract dysfunction. A total of 201 children aged 6 to 15 years (96 boys and 114 girls) were enrolled in the study. In addition to pain syndrome, cellular energy exchange disorder in the form of decreased level of intracellular antioxidant catalase enzyme and plasma antioxidant activity (PAO) was identified against the background of chronic constipation and biliary tract dysfunction in this group of children, which is evidence of decompensation of antioxidant protection in the acute stage of biliary tract dysfunctional disorders in children. The identified changes make a strong case for prescribing a drug with hepatoprotective, choleretic and antioxidant effects. The use of herbal extract of fresh artichoke leaves (Chophytol®, Mayoly Spindle, France) showed the relief of pain syndrome by Day 14 of treatment in 92% of patients (75% in the comparison group), nausea in 74% of children, constipation in 88% (50% of patients in the comparison group). It is important to detect an elevated α-tocopherol level and significantly reduced catalase level, which indicates the need to choose a drug with selective antioxidant activity, which does not change the α-tocopherol level. The introduction of the herbal extract of fresh artichoke leaves (Chophytol®) in the complex therapy of the studied patients accelerated the relief of the clinical symptoms of functional biliary tract disorders and reduced the frequency of constipation in children by 4 times as compared with the control group without significant effect on the α-tocopherol level.
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Zakharova, I. N., M. I. Pykov, I. V. Berezhnaya, et al. "Functional disorders of the biliary tract. What a pediatrician needs to know." Medical Council, no. 11 (July 16, 2018): 91–102. http://dx.doi.org/10.21518/2079-701x-2018-11-91-102.

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According to the frequency of contact with a doctor, abdominal pain in children is second only to respiratory diseases. Since the pain syndrome is a nonspecific manifestation of various pathologies, the doctor faces a serious diagnostic task, which is especially difficult in pediatric practice. One of the frequent causes of abdominal pain in children is a disruption of the function of the digestive tract, in particular, the dysfunction of the billiard tract. The article considers etiopathogenetic mechanisms of development of functional disorders of the biliary tract in children, classification in the light of the Rome IV consensus, modern low-invasive methods for diagnosing dysfunctions of the biliary tract. The ultrasound of the hepatobiliary zone was assessed. Questions are given for self-control.
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Minushkin, O. N., L. V. Maslovsky, N. V. Lvova, et al. "Biliary dysfunction (according to recommendations of Rome IV): diagnosis, treatment." Medical alphabet, no. 10 (June 17, 2020): 5–10. http://dx.doi.org/10.33667/2078-5631-2020-10-5-10.

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The paper presents information on modern functional disorders of the gastrointestinal tract and biliary system, based on the recommendations of the Rome IV. Own studies on the effectiveness of treatment of biliary functional disorders with Niaspam (mebeverine hydrochloride) are presented. We studied 30 patients with biliary pain and functional disorders of the gallbladder. As a result of studies, it was found that the symptoms of biliary dysfunction stop in 83.3 % of patients, the contractility of the gallbladder is restored in 86.7 %. No side effects have been reported.
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Kucheryavyy, Yu A., and M. F. Osipenko. "Chronic acalculous cholecystitis and biliary dysfunction: how does clinical diagnosis affect management?" Meditsinskiy sovet = Medical Council, no. 5 (May 13, 2021): 54–61. http://dx.doi.org/10.21518/2079-701x2021-5-54-61.

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Similar abdominal pain of biliary type in functional disorders of biliary tract and chronic acalculous cholecystitis causes objective difficulties to differentiate not only between each other, but also with other diseases of gastrointestinal tract. The clinical picture is so homogeneous and difficult to distinguish from cholelithiasis that some patients undergo unreasonable surgical interventions for CAC and FDBT. Individual publications pushing for such an aggressive strategy are sporadic and need to be clarified in larger studies. The first choice drugs for treatment of FDBT are spasmolytics; ursodeoxycholic acid drugs are used as adjuvant agents. In CAC, the initial therapy will be similar, but the treatment regimen can be expanded with targeted etiotropic (if the cause of cholecystitis is identified – giardiasis, opisthorchiasis, etc.) or empirical antimicrobial/antiparasitic therapy. The greatest interest today is caused by hymecromone – a drug with proven by both experimental and controlled studies combined choleretic, selective spasmolytic action, mediated effect of reducing bile lithogenicity and possible anti-inflammatory action. Hymecromone effectively relieves biliary pain without causing gallbladder contractions, which determines the possibility of its wide application both in CAC and FDBT, both in monotherapy and in combination with other agents, primarily with UDCA. In this article the issues of optimization of diagnostic and therapeutic strategy of management of patients with biliary pain to avoid unreasonable cholecystectomies in acalculous diseases of the biliary tract are considered.
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Shelukhina, S. V., A. S. Vasilevskaya, E. V. Markova, M. A. Butov, O. A. Maslova, and I. A. Zagravskaya. "Features of the management of patients with biliary dysfunctions with spasm of the sphincter of Oddi." Medical alphabet, no. 5 (May 7, 2024): 18–22. http://dx.doi.org/10.33667/2078-5631-2024-5-18-22.

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The aim. Assessment of clinical manifestations of biliary dysfunction, duodenal hypertension. The analysis of data on the effect of drugs of various pharmacological groups on the motor function of the gallbladder is carried out.Materials and methods. We were examined 60 patients (18–50 years old, mean age 41±4.6 years), mostly women (44). All patients underwent a general clinical examination, including blood and urine tests, biochemical blood parameters, ultrasound examination of the abdominal organs and monitoring of gallbladder contractility, esophagogastroduodenoscopy. The examined patients were divided into 2 groups of 30 patients.Results and conclusion. The use of choleretics for spasm of the sphincter of Oddi and symptoms of duodenal hypertension is not always justified. The leading link in the treatment of this type of biliary dysfunction are antispasmodics, which eliminate spasm of the sphincter zones, which restores the passage of bile through the biliary tract and reduces the phenomena of biliary insufficiency. Mebeverine hydrochloride also eliminates the phenomena of duodenal hypertension, which facilitates the removal of bile from the biliary tract. When choleretics are prescribed for the treatment of patients with biliary dysfunction with spasm of the sphincter of Oddi, it is quite possible that the course of this pathology will worsen.
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Sorokman, T. V., L. Yu Khlunovska, and I. Ya Lozyuk. "Frequency of involvement different parts of the gastrointestinal tract in the pathological process in children with biliary dysfunction." Modern pediatrics. Ukraine, no. 4(116) (May 26, 2021): 24–28. http://dx.doi.org/10.15574/sp.2021.116.24.

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The close anatomical and physiological connection of the digestive organs leads to a significant spread of functional disorders in various diseases. Purpose — to investigate the frequency and features of the clinical course of biliary dysfunction (BD) in children. Materials and methods. 66 children aged 10–18 years with BD were examined. The study included a complete clinical examination of children, laboratory and instrumental methods. To assess the severity of clinical symptoms in the examined patients was used traditional score scale of symptoms (0–3 points) and the frequency index (FI). Results. In most children, the database was combined with other functional and organic lesions of the digestive tract (n=56, 84.8%). The database was most often combined with chronic gastritis and duodenitis, as well as with functional motor disorders. FI in children with BD involved in the pathological process of the stomach and duodenum was the highest (0.59), and IR in children with BD and intestinal involvement was the lowest (0.23). The relationship between the frequency of combined pathology and the frequency of cases of increase in the size of the gallbladder (χ2=22.87 at a critical value of χ2=9.33 for the significance level p<0.01). Hyper- or hypofunctions of the biliary tract occurred with the same frequency. Conclusions. Biliary dysfunction in children is significantly more often combined with chronic gastritis and duodenitis, as well as with other functional disorders of the gastrointestinal tract (duodenogastric reflux). In children with biliary dysfunction and involvement in the pathological process of other parts of the gastrointestinal tract there is an increase in the frequency of exacerbations, more pronounced signs of dyspeptic syndrome on the background of pain with the same intensity and more often ultrasound reveals signs of gallbladder dysformation. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local Ethics Committee of all participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors. Key words: children, biliary dysfunction.
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Glick, Michael E., John C. Hoefs, and Hooshang Meshkinpour. "Glucose Intolerance and Hepatic, Biliary Tract and Pancreatic Dysfunction." Digestive Diseases 5, no. 2 (1987): 78–96. http://dx.doi.org/10.1159/000171165.

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Шестопалова, Є. С., С. А. Калмиков, and Ю. С. Калмикова. "Current issues of physical therapy in biliary tract dysfunction." Physical rehabilitation and recreational health technologies 5, no. 1 (2020): 52–57. http://dx.doi.org/10.15391/prrht.2020-5(1).07.

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Мета: розглянути особливості застосування фізичної терапії при дисфункції біліарного тракту. Матеріал і методи: теоретичний аналіз і узагальнення сучасних наукових даних щодо особливостей застосування реабілітаційних засобів при дисфункціональних розладах біліарного тракту. Результати: розглянуто механізм лікувальної дії фізичних вправ при дисфункції біліарного тракту; визначено особливості застосування фізичної терапії у період ремісії. Висновки: фізична терапія є невід´ємною частиною медичної реабілітації при дисфункціональних розладах біліарного тракту і залежить від форми дискінезії (гіпертонічно-гіперкінетична або гіпотонічно-гіпокінетична форма) та наявності органічної патології печінки, системи жовчовиділення, дванадцятипалої кишки, шлунку, товстого кишечника та інших органів.
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Dissertations / Theses on the topic "Biliary tract dysfunction"

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Васильєва, Олена Геннадіївна, Елена Геннадьевна Васильева, Olena Hennadiivna Vasylieva, Р. К. Кожина, Я. В. Сердюк та Т. В. Міхно. "Дисфункції жовчовивідних шляхів у дітей". Thesis, Сумський державний університет, 2015. http://essuir.sumdu.edu.ua/handle/123456789/41814.

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У практиці педіатра все частіше зустрічаються функціональні розлади жовчовивідних шляхів. Незважаючи на функціональний характер даної патології, вона супроводжується болем і диспепсичними розладами, особливо вираженими в дитячому віці, що погіршує якість життя дитини.
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Book chapters on the topic "Biliary tract dysfunction"

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GROSSMAN, Z. "Biliary Tract Obstruction/Hepatic Dysfunction." In Cost-Effective Diagnostic Imaging. Elsevier, 2006. http://dx.doi.org/10.1016/b978-0-323-03283-4.50007-4.

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Elmunzer, B. Joseph, and Grace H. Elta. "Biliary Tract Motor Function and Dysfunction." In Sleisenger and Fordtran's Gastrointestinal and Liver Disease. Elsevier, 2010. http://dx.doi.org/10.1016/b978-1-4160-6189-2.00063-9.

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Morgan, Katherine A., and David B. Adams. "Biliary Dyskinesia and Sphincter of Oddi Dysfunction." In Shackelford's Surgery of the Alimentary Tract. Elsevier, 2013. http://dx.doi.org/10.1016/b978-1-4377-2206-2.00106-8.

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Morgan, Katherine A., and David B. Adams. "Biliary Dyskinesia and Sphincter of Oddi Dysfunction." In Shackelford's Surgery of the Alimentary Tract, 2 Volume Set. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-323-40232-3.00110-2.

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"Dysfunction of the sphincter of Oddi complex and gallbladder." In Fast Facts: Pancreas and Biliary Tract Diseases. S. Karger AG, 2017. http://dx.doi.org/10.1159/000491324.

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Conference papers on the topic "Biliary tract dysfunction"

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Kurnikova, Irina, Shirin Gulova, Guzal Akhmadullina, Natalia Danilina, and Ikram Mokhammed. "Methods of computer simulation in the development of technology for the functional assessment of the state of the liver in patients." In 14th International Conference on Applied Human Factors and Ergonomics (AHFE 2023). AHFE International, 2023. http://dx.doi.org/10.54941/ahfe1003456.

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Most of the diseases associated with carbohydrate and fat metabolism disorders (type 2 diabetes mellitus, obesity, metabolic syndrome) lead to changes in the structure and function of liver cells, and the formed liver dysfunction negatively affects the further progression of the disease. The process of liver damage develops with varying intensity and does not immediately lead to irreversible consequences; therefore, dysfunction should be detected as early as possible, and the data obtained should be used to assess the current state and predict their reversibility.Study purpose. To create a quantitative assessment method that allows to assess the current functional state of the liver and to determine the reversibility of existing functional disorders and the severity of structural changes, to assess the prognosis of the course of the disease and the effectiveness of restorative measures.Instruments and Data Collection Procedure. Examination of patients, in addition to conventional methods, included an assessment of the absorptive-excretory function of the liver and biliary tract patency using a scintillation gamma camera (Siemens Symbia T16) with subsequent processing on the SUPER-SEGAMS computer system (Hungary). Freshly prepared Bromesida, 99mТс was administered intravenously at the rate of 1.1 MBq per kg of the patient's body weight, with a normal content of bilirubin in blood. Series of scintigrams allow to assess the passage of the drug visually through the blood-liver-ducts-intestine system, to characterize the anatomical features and organic changes in the biliary system. Quantitative analysis of the "activity-time" curves obtained from the areas of interest (the right lobe of the liver - 2 zones, the left lobe of the liver, the common bile duct, the intestinal area, the heart area) makes it possible to study the absorptive-excretory function of the liver.Results. By the method of mathematical modeling, a formula was obtained - the index of the functional activity of hepatocytes:IFAH= (-1,1564 + 0,0653 × BMI - 0,0144 × Tmax) × 100,where:IFAH - index of functional activity of hepatocytes (liver cells);BMI - body mass index (kg/m2)Tmax - indicator of the absorption function of the liver (min) - the time to reach the maximum accumulation of the radiopharmaceutical in the liver. It is an indicator of the function of polygonal liver cells (normal = 8-12 min).Functional activity of hepatocytes: from 0 to 9.9 - normal functional activity of hepatocytes; from 10 to 19.9 - the risk of developing functional disorders; from 20 to 29.9 - reversible dysfunction of hepatocytes (steatosis); more than 30 - irreversible (organic) liver dysfunction (steatohepatitis). With negative IFAH values - the influence of extrahepatic factors, such as diseases that accelerate metabolism at the cellular level (thyrotoxicosis), taking drugs in violation of the prescriptions before these studies.The originality and novelty of the technique are confirmed by the patent – “A method for diagnosing fatty hepatosis” (patent RU 2 578 080 C2 dated February 19, 2016).The method was tested in clinical practice and the data obtained confirmed the high diagnostic accuracy (95%) of the proposed method for calculating the index of IFAH.Conclusion: the discussed method allows doctors to evaluate not only the current functional state of the liver, but also to determine the reversibility of existing functional disorders and the severity of structural changes; also could be used to evaluate the prognosis of the course of the disease and the effectiveness of restorative measures. It is characterized by relative ease of implementation. Only one parameter — Tmax is required, after which the study can be completed.
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