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Journal articles on the topic 'Bioactive properties'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 June 2025

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Selvaraj, Jesupriya Poornakala, Alagesan Arumugam, Yuvaraja Arumugam, and Menaka Chinnusamy. "Bioactive compounds and therapeutic properties of millet bran." Agriculture Association of Textile Chemical and Critical Reviews 13, no. 1 (2025): 63–70. https://doi.org/10.21276/aatccreview.2025.13.01.62.

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Millet bran is a by-product obtained during the processing of millet and is packed with a variety of nutrients. It is made up of the outer layer, seed coat, aleurone layer, a small part of the embryo, and the endosperm [1]. It makes up about 6–8% of millet's total weight [2]. This by-product is typically thrown away during the milling and refining of cereal grains due to its appearance, taste, and ability to extend shelf life [3]. It contains bioactive elements such as fibers, lipids, proteins, and minerals [4]. Additionally, millet bran is higher in vitamins B, C, and E compared to the kernels [5,6]. Moreover, millet bran is a good source of phytochemicals, including flavonoids, polyphenols, phytosterols, dietary fiber, and other bioactive substances [4]. Beyond its high fiber content, millet bran is also a rich source of essential oils. The fat content of the millet small bran had unsaturated fatty acids, linoleic acid, linolenic acid, arachidonic acid and other essential fatty acids unsaturated fatty acids [7]. This review discusses the phytochemical potential of millet bran and provided valuable insights into these compounds and their possible therapeutic properties in disease management.

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Syta, Ewa, Grażyna Ginalska, and Paulina Kazimierczak. "Bioactive properties of carnosine." Medycyna Ogólna i Nauki o Zdrowiu 24, no. 2 (2018): 96–100. http://dx.doi.org/10.26444/monz/90885.

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Vulić, Jelena, Ksenija Bibovski, Vanja Šeregelj, et al. "Chemical and Biological Properties of Peach Pomace Encapsulates: Chemometric Modeling." Processes 10, no. 4 (2022): 642. http://dx.doi.org/10.3390/pr10040642.

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Background: Bioactive compounds need to resist food processing, be released from the food matrix, and be bioaccessible in the gastrointestinal tract in order to provide health benefits. Bioactive compounds isolated from peach pomace (PP) were encapsulated using four different wall materials to improve their stability and to evaluate the effects of in vitro gastrointestinal digestion, as well as chemometric modeling among obtained encapsulates. Methods: Phenolics and carotenoids content, antioxidant, antihyperglycemic, anti-inflammatory, and cell growth activities were evaluated after gastric and intestinal digestion steps. Chemometrics classification analysis–principal component analysis and hierarchical cluster analysis revealed grouping among encapsulates. Results: The encapsulation of PP bioactive compounds showed a protective effect against pH changes and enzymatic activities along digestion, and thereby contributed to an increase in their bioaccessibility in gastric and intestinal fluids. Conclusions: The obtained results suggest protein and polysaccharide carriers and the freeze-drying technique, as an efficient method for the encapsulation of bioactives from PP, could find use in the food and pharmaceutical industry.

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Mateos, Raquel, José Ricardo Pérez-Correa, and Herminia Domínguez. "Bioactive Properties of Marine Phenolics." Marine Drugs 18, no. 10 (2020): 501. http://dx.doi.org/10.3390/md18100501.

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Phenolic compounds from marine organisms are far less studied than those from terrestrial sources since their structural diversity and variability require powerful analytical tools. However, both their biological relevance and potential properties make them an attractive group deserving increasing scientific interest. The use of efficient extraction and, in some cases, purification techniques can provide novel bioactives useful for food, nutraceutical, cosmeceutical and pharmaceutical applications. The bioactivity of marine phenolics is the consequence of their enzyme inhibitory effect and antimicrobial, antiviral, anticancer, antidiabetic, antioxidant, or anti-inflammatory activities. This review presents a survey of the major types of phenolic compounds found in marine sources, as well as their reputed effect in relation to the occurrence of dietary and lifestyle-related diseases, notably type 2 diabetes mellitus, obesity, metabolic syndrome, cancer and Alzheimer’s disease. In addition, the influence of marine phenolics on gut microbiota and other pathologies is also addressed.

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Brauer, Delia S. "Bioactive Glasses-Structure and Properties." Angewandte Chemie International Edition 54, no. 14 (2015): 4160–81. http://dx.doi.org/10.1002/anie.201405310.

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CORRAL NUÑEZ, Camila, Cristian COVARRUBIAS, Eduardo FERNANDEZ, and Osmir Batista de OLIVEIRA JUNIOR. "Enhanced bioactive properties of BiodentineTM modified with bioactive glass nanoparticles." Journal of Applied Oral Science 25, no. 2 (2017): 177–85. http://dx.doi.org/10.1590/1678-77572016-0209.

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Cunha, Sara A., Ezequiel R. Coscueta, Paulo Nova, Joana Laranjeira Silva, and Maria Manuela Pintado. "Bioactive Hydrolysates from Chlorella vulgaris: Optimal Process and Bioactive Properties." Molecules 27, no. 8 (2022): 2505. http://dx.doi.org/10.3390/molecules27082505.

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Microalgae have been described as a source of bioactive compounds, such as peptides. Microalgae are easy to produce, making them a sustainable resource for extracting active ingredients for industrial applications. Several microalgae species have interesting protein content, such as Chlorella vulgaris with around 52.2% of protein, making it promising for peptide hydrolysate production. Therefore, this work focused on the production of water-soluble hydrolysates rich in proteins/peptides from the microalgae C. vulgaris and studied bioactive properties. For that, a design of experiments (DOE) was performed to establish the optimal conditions to produce hydrolysates with higher levels of protein, as well as antioxidant and antihypertensive properties. Four experimental factors were considered (cellulase percentage, protease percentage, hydrolysis temperature, and hydrolysis duration) for three responses (protein content, antioxidant activity, and antihypertensive activity). The optimal conditions determined by the DOE allowed producing a scaled-up hydrolysate with 45% protein, with antioxidant activity, measured by oxygen radical absorbance capacity assay, of 1035 µmol TE/g protein, IC50 for angiotensin-converting enzyme inhibition activity of 286 µg protein/mL, and α-glucosidase inhibition of 31% (30 mg hydrolysate/mL). The obtained hydrolysates can be used as functional ingredients for food and nutraceuticals due to their antioxidant, antihypertensive, and antidiabetic potential. Moreover, the antioxidant potential of the extracts may be relevant for the cosmetic industry, especially in antiaging formulations.

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Moysidou, Anastasia Maria, Konstantina Cheimpeloglou, Spyridoula Ioanna Koutra, Marios Argyrios Finos, Anna Ofrydopoulou, and Alexandros Tsoupras. "A Comprehensive Review on the Antioxidant and Anti-Inflammatory Bioactives of Kiwi and Its By-Products for Functional Foods and Cosmetics with Health-Promoting Properties." Applied Sciences 14, no. 14 (2024): 5990. http://dx.doi.org/10.3390/app14145990.

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Kiwi’s increased popularity as a healthy fruit with several agro-food applications has increased the amount of bio-waste produced like leaf, peel, and seed by-products, usually combined to form a kiwi pomace, which increases the environmental footprint of kiwi fruit and waste management costs. The aim of the present study is to thoroughly review and outline the nutritional content and bioactive components of both kiwi fruit and its by-products, as well as the innovative approaches to obtain and valorize kiwi’s bioactives, phytochemicals, vitamins, and nutrients in several functional food products, nutraceuticals, and cosmetics applications with health-promoting properties. The antioxidant and anti-inflammatory properties and mechanisms of action of the extracted polyphenols, flavonoids, flavones, organic acids, and other bioactive components in both the fruit and in its functional products are also elucidated. Emphasis is given to those bioactive ingredients and extracts from kiwi by-products that can be valorized in various functional foods, supplements, nutraceuticals, nutricosmetics, cosmeceuticals, and cosmetics-related applications, with antioxidant and anti-inflammatory health-promoting properties. Characteristic examples with reported health benefits are the functional kiwi fruit jelly (FKJ),fermented kiwi fruit products like wine, starchy kiwi fruit flour (SKF), and kiwi-derived functional protein bars, cheese and flour, as well as several nutraceuticals and functional cosmetics with kiwi bioactives improving their antioxidant, antiaging, and photoprotective properties, collagen synthesis, skin density, hydration, elasticity, and the wound healing process, while beneficially reducing skin roughness, wrinkles, hyperpigmentation, keratinocyte death, and DNA and cell damage. The limitations and future perspectives for these kiwi bioactive-based applications are also discussed.

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Badr, Ahmed Noah, Karolina Gromadzka, Mohamed Gamal Shehata, Kinga Stuper-Szablewska, Kinga Drzewiecka, and Adel Gabr Abdel-Razek. "Prospective antimycotoxigenic action of wild Opuntia ficus-indica by-products." Czech Journal of Food Sciences 38, No. 5 (2020): 308–14. http://dx.doi.org/10.17221/11/2020-cjfs.

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Numerous natural compounds perform pharmaceutical, antimycotic and antitoxic purposes in the body system. The aim was to evaluate new phytoconstituents that provide antimycotoxigenic properties against mycotoxins. Bioactive materials chosen were fruit peels and cladodes of wild Opuntia ficus-indica containing a measurable quantity of bioactive phytochemicals. The highest concentration of bioactive metabolites was recorded for protocatechuic and t-cinnamic acids. A reduction effect of bioactives was estimated against aflatoxins, ochratoxin A and zearalenone in a simulated body system. Antifungal activity was determined in liquid media to evaluate antimycotic properties. Lyophilised extracts caused an aflatoxin reduction in media by 14.65% to 23.77% for fruit peels and cladodes, respectively. It caused a decrease of 59% zearalenone and 51% of ochratoxin A in a in a simulated body fluid. The cladode extract manifested better antimycotic and antimycotoxigenic characteristics due to its bioactive contents. These results support a modern antimycotoxin trend of food preservation that has a considerable impact on food safety.

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LI, YING, CHI MUN CHEAH, HENGKY CHANG, LEONARD LOH, and ADELINE KUM. "PREPARATION AND CHARACTERIZATION OF BIOACTIVE COMPOSITES OF PCL/BIOACTIVE FILLERS." International Journal of Modern Physics B 24, no. 01n02 (2010): 128–35. http://dx.doi.org/10.1142/s0217979210064058.

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A variety of bioactive composites have been invested over the last two decades as substitute materials for diseased or damaged tissues in the human body. In this paper, bioactive composites were prepared using polycaprolactone ( PCL ) and hydroxyapatite ( HA ). The influence of micro-sized and nano-sized HA on composite properties was investigated. The nano- HA was prepared by wet chemical co-precipitation reaction method. Studies of biocomposite specimen morphology were performed by Field-emission scanning electron microscopy (SEM). XRD (X-Ray Diffraction) and DSC (Differential scanning calorimetry) were used to assess the crystal structure of HA and thermal properties of the composites, respectively. The synthesized nano- HA is found to be of high purity HA structure. The relationship between composition, structure and properties was studied. Different methods to prepare uniform composites were tried, and the outcome of this work suggests that by proper manipulation of biodegradable polymers and bioactive ceramics through material design, bioactive composites with controlled properties might be achievable.

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Sadiq, Uzma, Harsharn Gill, and Jayani Chandrapala. "Casein Micelles as an Emerging Delivery System for Bioactive Food Components." Foods 10, no. 8 (2021): 1965. http://dx.doi.org/10.3390/foods10081965.

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Bioactive food components have potential health benefits but are highly susceptible for degradation under adverse conditions such as light, pH, temperature and oxygen. Furthermore, they are known to have poor solubilities, low stabilities and low bioavailabilities in the gastrointestinal tract. Hence, technologies that can retain, protect and enable their targeted delivery are significant to the food industry. Amongst these, microencapsulation of bioactives has emerged as a promising technology. The present review evaluates the potential use of casein micelles (CMs) as a bioactive delivery system. The review discusses in depth how physicochemical and techno-functional properties of CMs can be modified by secondary processing parameters in making them a choice for the delivery of food bioactives in functional foods. CMs are an assembly of four types of caseins, (αs1, αs2, β and κ casein) with calcium phosphate. They possess hydrophobic and hydrophilic properties that make them ideal for encapsulation of food bioactives. In addition, CMs have a self-assembling nature to incorporate bioactives, remarkable surface activity to stabilise emulsions and the ability to bind hydrophobic components when heated. Moreover, CMs can act as natural hydrogels to encapsulate minerals, bind with polymers to form nano capsules and possess pH swelling behaviour for targeted and controlled release of bioactives in the GI tract. Although numerous novel advancements of employing CMs as an effective delivery have been reported in recent years, more comprehensive studies are required to increase the understanding of how variation in structural properties of CMs be utilised to deliver bioactives with different physical, chemical and structural properties.

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Ouma, Stephen, Richard Kagia, and Faith Kamakia. "Determination of pharmacological activity of bioactives in Allium sativum using computational analysis." F1000Research 12 (February 9, 2023): 151. http://dx.doi.org/10.12688/f1000research.130105.1.

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Introduction: Use of natural products for management of diseases has increased widely due to the belief that natural products are less toxic than conventional medicines. Natural products have been utilised for management of chronic diseases such as diabetes and cancers. Respiratory infections have also been managed using natural products. Allium sativum is one of the natural products that has been utilised in the management of SARS-CoV infections, diabetes and cancer. Methods: This study was aimed at screening bioactive agents in Allium sativum using computational analysis. The targets of the bioactive agents were predicted using SwissTargetPrediction tools. Molecular docking followed, where the docking energies of the bioactive agents to the targets were generated. The bioactive agents were analysed for pharmacokinetics properties using SwissADME as well as toxicity profiles using the ProTox II webserver. The docking scores, toxicities and pharmacokinetics profiles of the bioactive agents in Allium sativum were compared with those of reference compounds. Results: All the bioactives showed lower docking scores than the reference compounds. The bioactives, however, showed some activity on specific receptors such as carbonic anhydrases, cyclooxygenase and ghrelin. All the bioactives showed high gastrointestinal tract absorption and none violated Lipinski’s rule of five. Diallyl trisulphide was predicted to be most lethal, with an LD50 of 100mg/kg, while was the safest, with 8000mg/kg. Conclusions: In conclusion, bioactives showed lower docking scores than the reference compounds, therefore overall pharmacological activity could be attributed to synergy between the bioactives for a particular receptor.

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Benahmed Djilali, Adiba, Abdelouahab Benseddik, Halima Boughellout, Karim Allaf, and Mohamed Nabiev. "Biological and functional properties of vine leaves." North African Journal of Food and Nutrition Research 5, no. 11 (2021): 43–52. http://dx.doi.org/10.51745/najfnr.5.11.43-52.

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Aims: The main objective of the present research work was to evaluate the (phytochemical, biochemical, and antimicrobial) properties of Muscat of Alexandria leaf powder and develop new functional dairy product using the mixture lactic bacteria and vine leaf powder as prebiotic for health applications (gastric and cardiac problems, etc.). Material and Methods: Various nutritional parameters of the vine leaf powder namely: pH, acidity, water content, ashes, salts, fatty acids) were determined. Also, their bioactive substances (TPC, total flavonoids content, tannin content, soluble-water polysaccharides) were extracted and quantified using referenced methods. The evaluation of antimicrobial activity of these substances was carried out by disc method. Vine leaf powder and aqueous extract were used to improve acidification kinetic. Also, functional yogurt using the mixture (lactic bacteria and vine leaf powder as prebiotic) was prepared. Results: The main results demonstrate that, the vine leaf powder contains high-value components such as salts with a high k/Na ratio, fatty acids (palmitic, linolenic and oleic) and bioactives (polyphenols, tannins and polysaccharides). The antimicrobial activity of these bioactive metabolites varies depending on the resistance of the strains tested. On the other hand, vine leaf TPC and polysaccharides act as an antifungal against (C. albicans and A. niger) and increase the acidification rate and consequently the growth and activity of the lactic bacteria in the yogurt, which suggests a probable prebiotic effect. Conclusions: Through this study, we have demonstrated the high content of vine leaves in several bioactive compounds such as polyphenols, flavonoids, tannins and polysaccharides. These compounds display an interesting antimicrobial activity and an extensive effect on the activity of lactic bacteria, which suggests a prebiotic effect. Keywords: Bioactive substances, antimicrobial activity, prebiotic, vine leaves.

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Ismaiel, Lama, Valeria Rizzo, Carla Di Mattia, et al. "Oil-in-Water Emulsions Made of Pistachio Oil: Physical and Chemical Properties and Stability." Foods 14, no. 1 (2024): 60. https://doi.org/10.3390/foods14010060.

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Pistachio nuts are valued for their sensory qualities, nutritional benefits, and health-promoting properties. Pistachio oil has also gained interest for its bioactive compounds, though these are sensitive to processing and environmental stresses. While pistachio-based products are commercially available, little research has addressed the emulsifying properties of crude pistachio oil or its impact on the stability and bioactive profile of oil-in-water (O/W) emulsions. This study evaluated the emulsion-forming abilities of two commercial pistachio oils (PO1, PO2), their physical and oxidative stability during emulsification, and the effects of emulsifier concentration over short-term storage (7 days, 4 °C). O/W emulsions were prepared using 20% (w/w) oil and Tween 20 (0.5% and 1% w/w) in phosphate buffer and homogenized under high pressure. The emulsions were analyzed for particle size, fatty acid profile, antioxidants, and oxidative state. The results revealed differences in fatty acid composition, oxidative stability, and bioactive content between the oils and their emulsions. PO1 showed higher levels of bioactives compared to PO2. Emulsification increased the peroxide value of the oil phase, confirming its pro-oxidant effects. The results of this study demonstrate the potential of pistachio oil to create stable O/W emulsions rich in bioactives, offering new opportunities for healthy emulsified food products.

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Tsoupras, Alexandros, Donal Moran, Thomas Byrne, et al. "Anti-Inflammatory and Anti-Platelet Properties of Lipid Bioactives from Apple Cider By-Products." Molecules 26, no. 10 (2021): 2869. http://dx.doi.org/10.3390/molecules26102869.

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The valorization of food industry by-products as sources of bioactive compounds is at the forefront of research in functional foods and nutraceuticals. This study focuses on bioactives of apple cider by-products (ACBPs) with putative cardio-protective properties. Total lipids (TLs) were extracted from ACBPs of apple varieties that are low (ACBP1), medium (ACBP2), and high (ACBP3) in tannins and were further separated into polar lipids (PLs) and neutral lipids (NLs). The functionality of these lipid extracts and of their HPLC-derived lipid fractions/PL subclasses were assessed in vitro against human platelet aggregation induced by the thrombotic and inflammatory platelet agonists platelet-activating factor (PAF) and adenosine diphosphate (ADP). The fatty acid profile of PLs and their most bioactive lipid fractions were evaluated by GC–MS analysis. The PL extracts exhibited higher specificity against the PAF-induced platelet aggregation compared to their anti-ADP effects, while TL and NL showed lower bioactivities in all ACBPs. HPLC analysis unveiled that the most bioactive PL from all ACBPs were those in PL fraction 3 containing phosphatidylcholines (PCs). PLs from all ACBPs and their PC bioactives were rich in polyunsaturated fatty acids (PUFAs) and especially in the essential omega-6 (n-6) linoleic acid (LA) and omega-3 (n-3) alpha linolenic acid (ALA), with favorably low values of the n-6/n-3 PUFA ratio, thus providing a rationale for their higher anti-inflammatory bioactivities. Within this study, highly bioactive PL compounds with strong anti-inflammatory and anti-platelet properties were identified in ACBPs, which can be potentially utilized for producing cardio-protective functional foods and/or nutraceuticals.

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Sharma, Manoj B., Hend A. M. Abdelmohsen, Özlem Kap, et al. "Poly(2-Hydroxyethyl Methacrylate) Hydrogel-Based Microneedles for Bioactive Release." Bioengineering 11, no. 7 (2024): 649. http://dx.doi.org/10.3390/bioengineering11070649.

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Microneedle arrays are minimally invasive devices that have been extensively investigated for the transdermal/intradermal delivery of drugs/bioactives. Here, we demonstrate the release of bioactive molecules (estradiol, melatonin and meropenem) from poly(2-hydroxyethyl methacrylate), pHEMA, hydrogel-based microneedle patches in vitro. The pHEMA hydrogel microneedles had mechanical properties that were sufficiently robust to penetrate soft tissues (exemplified here by phantom tissues). The bioactive release from the pHEMA hydrogel-based microneedles was fitted to various models (e.g., zero order, first order, second order). Such pHEMA microneedles have potential application in the transdermal delivery of bioactives (exemplified here by estradiol, melatonin and meropenem) for the treatment of various conditions.

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Alsharairi, Naser A. "A Review on Bioactive Compounds and Pharmacological Activities of Citrus unshiu." Applied Sciences 15, no. 8 (2025): 4475. https://doi.org/10.3390/app15084475.

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Citrus constitutes a group of fruit crops that include lemons, limes, mandarins, oranges, and grapefruits. These citrus have a variety of essential nutrients and bioactive compounds that exert several pharmacological properties, including antioxidant, anti-inflammatory, anticancer, anti-diabetic, and anti-obesity. The Satsuma mandarin, also known as Citrus unshiu Marc. (C. unshiu), is one of the most popular citrus types. This is mostly due to its seedless nature, early maturity, and highly valued commercial trait in the citrus sector. The pharmacological properties and phytochemicals of the two main citrus fruits—sweet oranges (C. sinensis) and lemons (C. limon)—are given more attention. Satsuma mandarin has not, however, had its therapeutic properties thoroughly examined and explored. Therefore, the purpose of this review is to use multiple databases to compile the information currently available on the pharmacological properties and bioactive compounds of C. unshiu. The findings indicate that C. unshiu bioactives (hesperidin; hesperetin; nobiletin; narirutin; naringin; naringenin; tangeretin; 3,5,6,7,8,3′,4′-heptamethoxyflavone; neoponcirin; synephrine; quercetin; quercetagetin; rutin; β-cryptoxanthin; and pectin) exert in vitro/vivo anticancer, anti-obesity, anti-diabetic, cardioprotective, gastroprotective, neuroprotective, hepatoprotective, skin-protective, nasal airway-protective, lipid-lowering, antioxidant, anti-inflammatory, and anti-microbial activities. Future experimental investigations into the potential health benefits of C. unshiu could contribute to a better understanding of the mechanisms behind its therapeutic activities. Clinical studies are necessary to assess the therapeutic properties of C. unshiu bioactives. The therapeutic potential of C. unshiu bioactives should be determined through preclinical in vivo animal studies before they can be applied in clinical settings.

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Anvar, Amir Ali, and Bahareh Nowruzi. "Bioactive Properties of Spirulina: A Review." Microbial Bioactives 4, no. 1 (2021): 134–42. http://dx.doi.org/10.25163/microbbioacts.412117b0719110521.

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Spirulina is a single-cell protein rich in all essential nutrients and vitamins and can be used to produce functional food. Spirulina is a single-cell protein rich in all essential nutrients and vitamins and can be used to produce functional food. In fact, one of the most important problems in the food industry is the use of synthetic food additives that increase the risk of cancer. Therefore, efforts are being made around the world today to isolate new and safe antioxidants from natural sources. Among these, the natural products of cyanobacteria are an important source of new drug compounds. Natural bioactive products not only have medicinal value themselves but are also used as building models to create synthetic analogs. The chemical composition of Spirulina includes protein (70-55%), carbohydrates (25-25%), essential fatty acids (18%), vitamins, minerals, and pigments such as carotene, chlorophyll A and phycocyanin. Obviously, the introduction of valuable properties of cyanobacteria Spirulina can be a suitable substitute for many antimicrobial compounds and synthetic antioxidants that not only pose no risk to the consumer but can also improve consumer health. In this review, we have discussed the important nutrient, bioactive properties, and immunological applications of Spirulina. The current research suggests that spirulina supplementations have been accepted by global accreditation as a safe nutritional and dietary supplement.

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Milusheva, R. Yu, and S. Sh Rashidova. "Bioactive properties of nanochitosan Bombyx mori." Polymer Science, Series C 59, no. 1 (2017): 29–34. http://dx.doi.org/10.1134/s1811238217010088.

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Özcan, M. M. "Moringa spp: Composition and bioactive properties." South African Journal of Botany 129 (March 2020): 25–31. http://dx.doi.org/10.1016/j.sajb.2018.11.017.

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Smith, M. A. L., K. A. Marley, D. Seigler, K. W. Singletary, and B. Meline. "Bioactive Properties of Wild Blueberry Fruits." Journal of Food Science 65, no. 2 (2000): 352–56. http://dx.doi.org/10.1111/j.1365-2621.2000.tb16006.x.

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Yildiz, Hilal, and Neva Karatas. "Microbial exopolysaccharides: Resources and bioactive properties." Process Biochemistry 72 (September 2018): 41–46. http://dx.doi.org/10.1016/j.procbio.2018.06.009.

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Queiroz Zepka, Leila, Eduardo Jacob-Lopes, and María Roca. "Catabolism and bioactive properties of chlorophylls." Current Opinion in Food Science 26 (April 2019): 94–100. http://dx.doi.org/10.1016/j.cofs.2019.04.004.

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Kokubo, Tadashi. "Bioactive glass ceramics: properties and applications." Biomaterials 12, no. 2 (1991): 155–63. http://dx.doi.org/10.1016/0142-9612(91)90194-f.

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Kokubo, T., H. M. Kim, M. Kawashita, and T. Nakamura. "REVIEW Bioactive metals: preparation and properties." Journal of Materials Science: Materials in Medicine 15, no. 2 (2004): 99–107. http://dx.doi.org/10.1023/b:jmsm.0000011809.36275.0c.

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Juhasz, Judith A., and Serena M. Best. "Bioactive ceramics: processing, structures and properties." Journal of Materials Science 47, no. 2 (2011): 610–24. http://dx.doi.org/10.1007/s10853-011-6063-x.

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Osés, S. M., A. Pascual-Maté, M. A. Fernández-Muiño, T. M. López-Díaz, and M. T. Sancho. "Bioactive properties of honey with propolis." Food Chemistry 196 (April 2016): 1215–23. http://dx.doi.org/10.1016/j.foodchem.2015.10.050.

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Hager, Roland, Johannes Pitsch, Jakob Kerbl-Knapp, et al. "A High-Content Screen for the Identification of Plant Extracts with Insulin Secretion-Modulating Activity." Pharmaceuticals 14, no. 8 (2021): 809. http://dx.doi.org/10.3390/ph14080809.

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Bioactive plant compounds and extracts are of special interest for the development of pharmaceuticals. Here, we describe the screening of more than 1100 aqueous plant extracts and synthetic reference compounds for their ability to stimulate or inhibit insulin secretion. To quantify insulin secretion in living MIN6 β cells, an insulin–Gaussia luciferase (Ins-GLuc) biosensor was used. Positive hits included extracts from Quillaja saponaria, Anagallis arvensis, Sapindus mukorossi, Gleditsia sinensis and Albizia julibrissin, which were identified as insulin secretion stimulators, whereas extracts of Acacia catechu, Myrtus communis, Actaea spicata L., Vaccinium vitis-idaea and Calendula officinalis were found to exhibit insulin secretion inhibitory properties. Gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) were used to characterize several bioactive compounds in the selected plant extracts, and these bioactives were retested for their insulin-modulating properties. Overall, we identified several plant extracts and some of their bioactive compounds that may be used to manipulate pancreatic insulin secretion.

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Agatha Ngukuran Jikah and Gift Onyinye Christopher. "The bioactive constituents and biological properties of Trigonella Foenum-Graecum (Fenugreek): A comprehensive review." International Journal of Science and Research Archive 13, no. 1 (2024): 2140–49. http://dx.doi.org/10.30574/ijsra.2024.13.1.1679.

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Fenugreek; the extremely nutritional plant of the Fabaceae family ranks amongst the oldest therapeutic plants used in traditional medicine. The plant has a broad –spectrum of pharmacological and biological activities which are traceable to its bioactive compounds and protective nutrients contained such as; flavonoids, diosgenin, saponins, galactomannans, trigonellin, essential oils, coumarins, 4-hydroxyisoleucine and scopoletin. These bioactive compounds elicit nutraceutical, immunomodultory, antioxidant, anti-atherogenic, anti-oxidative, anti-hyperlipidemic, hypoglycaemic, anticarcinogenic, antinociceptive, anti-inflammatory and anti-hypertensive effects via various mechanisms against common chronic diseases. Moreover, the plant also has protective effects on the digestive, cardiovascular, endocrine, and reproductive systems. This article considers the role of fenugreek contained bioactives on human milk production and lactation. The other biological activities are also discussed.

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Shahidi, Fereidoon, and Ying Zhong. "Bioactive Peptides." Journal of AOAC INTERNATIONAL 91, no. 4 (2008): 914–31. http://dx.doi.org/10.1093/jaoac/91.4.914.

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Abstract Peptides with biological activities, released during gastrointestinal digestion or food processing, play an important role in metabolic regulation and modulation, suggesting their potential use as nutraceuticals and functional food ingredients for health promotion and disease risk reduction. Many studies have reported that peptides from various food sources possess bioactivities, including antihypertensive, antioxidant, anticancer, antimicrobial, and opioid activities as well as immunomodulatory and cholesterol-lowering effects. More studies are being performed exploring the sources, bioavailabilities, and possible physiological/functional properties and the mechanisms of action of bioactive peptides. Technological approaches in terms of peptide preparation, purification, and characterization have also been investigated.

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Aguilar-Pérez, Fernando J., Rossana F. Vargas-Coronado, Jose M. Cervantes-Uc, Juan V. Cauich-Rodríguez, Cristian Covarrubias, and Merhdad Pedram-Yazdani. "Preparation and bioactive properties of nano bioactive glass and segmented polyurethane composites." Journal of Biomaterials Applications 30, no. 9 (2016): 1362–72. http://dx.doi.org/10.1177/0885328215626361.

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Lei, Bo, Xiaofeng Chen, Yingjun Wang, Naru Zhao, Chang Du, and Liming Fang. "Synthesis and bioactive properties of macroporous nanoscale SiO2–CaO–P2O5 bioactive glass." Journal of Non-Crystalline Solids 355, no. 52-54 (2009): 2678–81. http://dx.doi.org/10.1016/j.jnoncrysol.2009.09.029.

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Martin Alain, Mune Mune. "Prediction and Evaluation of Bioactive Properties of Cowpea Protein Hydrolysates." Journal of Food Biochemistry 2023 (February 13, 2023): 1–12. http://dx.doi.org/10.1155/2023/9095113.

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Cowpea protein hydrolysates were prepared using thermolysin, alcalase, and trypsin and analysed for bioactive properties, and then, the release of bioactive peptides was investigated in silico. It was found that the degree of hydrolysis reached 48% after 24 h hydrolysis with alcalase. The hydrolysate prepared using alcalase showed higher ACE inhibitory (62%) and DPPH scavenging activity (19%). SDS-PAGE analysis revealed that vignin was the major protein in cowpea protein isolate. In silico analysis indicated the presence of potential bioactive peptides with potent bioactivity in the primary structure of proteins. The 3D structure of proteins was built, upon which bioactive peptides were mapped using their location in the primary structure. The secondary structure and solvent accessible surface around each bioactive peptide were then calculated. On this basis, the higher degree of hydrolysis and bioactive properties of cowpea protein hydrolysate prepared by alcalase were explained, and structural factors influencing the release of bioactive peptides were investigated.

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Gupta, Neeraj, Vikash Kumar Vyas, and Apurba Mandal. "Studies of Substitution Effect of B2O3 on Structure and Properties of 1393 Bioactive Glass." Oriental Journal Of Chemistry 37, no. 6 (2021): 1409–14. http://dx.doi.org/10.13005/ojc/370619.

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Bioactive glass is mainly familiar for its outstanding biocompatibility and bioactive behavior and it’s known for important bone bonding ability. Bioactive glass is a reproduction fillet joint meant for orthopedic in addition to periodontal function of one of the leading applications. A silica based bioactive glass designated 1393 bio-glass® [wt. % (53) SiO2 – (6) Na2O – (12) K2O – (20) CaO – (5) MgO – (4)P2O5] 1393 is like 45S5 bio-glass®, other than it has a high SiO2 content and network modifiers, such as potassium oxide and magnesium oxide, bioactive glass, is also used clinically. In this communication, study of destructive (DT) & non-destructive (NDT) behavior of SiO2 replaced by boron trioxide (B2O3) in 1393 bioactive glass has been reported. The formed amorphous phase using x-ray diffraction (X-RD) analysis in bioactive glass will be identified. Density and mechanical properties measured using different types of instrument and using ultrasonic wave velocities study the elastic properties like young’s , shear, bulk modulus and Poisson’s ratio of bioactive glasses were reported. The results point to the substitution of boron trioxide in 1393 bioactive glass enhanced its density, mechanical properties and elastic properties, similarly for silica.

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Huq, Md Amdadul, and Shahina Akter. "Bioactive Polymer Materials with Antibacterial Properties: An Editorial." Polymers 17, no. 3 (2025): 394. https://doi.org/10.3390/polym17030394.

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Almulhim, Khalid S., Mariam Raza Syed, Norah Alqahtani, et al. "Bioactive Inorganic Materials for Dental Applications: A Narrative Review." Materials 15, no. 19 (2022): 6864. http://dx.doi.org/10.3390/ma15196864.

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Over time, much attention has been given to the use of bioceramics for biomedical applications; however, the recent trend has been gaining traction to apply these materials for dental restorations. The bioceramics (mainly bioactive) are exceptionally biocompatible and possess excellent bioactive and biological properties due to their similar chemical composition to human hard tissues. However, concern has been noticed related to their mechanical properties. All dental materials based on bioactive materials must be biocompatible, long-lasting, mechanically strong enough to bear the masticatory and functional load, wear-resistant, easily manipulated, and implanted. This review article presents the basic structure, properties, and dental applications of different bioactive materials i.e., amorphous calcium phosphate, hydroxyapatite, tri-calcium phosphate, mono-calcium phosphate, calcium silicate, and bioactive glass. The advantageous properties and limitations of these materials are also discussed. In the end, future directions and proposals are given to improve the physical and mechanical properties of bioactive materials-based dental materials.

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Bokić, Jelena, Jovana Kojić, Jelena Krulj, et al. "Bioactive, Mineral and Antioxidative Properties of Gluten-Free Chicory Supplemented Snack: Impact of Processing Conditions." Foods 11, no. 22 (2022): 3692. http://dx.doi.org/10.3390/foods11223692.

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This study aimed to investigate the impact of chicory root addition (20–40%) and extrusion conditions (moisture content from 16.3 to 22.5%, and screw speed from 500 to 900 rpm) on bioactive compounds content (inulin, sesquiterpene lactones, and polyphenols) of gluten-free rice snacks. Chicory root is considered a potential carrier of food bioactives, while extrusion may produce a wide range of functional snack products. The mineral profiles were determined in all of the obtained extrudates in terms of Na, K, Ca, Mg, Fe, Mn, Zn, and Cu contents, while antioxidative activity was established through reducing capacity, DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) tests. Chicory root addition contributed to the improvement of bioactive compounds and mineral contents, as well as antioxidative activities in all of the investigated extrudates in comparison to the pure-rice control sample. An increase in moisture content raised sesquiterpene lactones and minerals, while high screw speeds positively affected polyphenols content. The achieved results showed the important impact of the extrusion conditions on the investigated parameters and promoted chicory root as an attractive food ingredient in gluten-free snack products with high bioactive value.

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Tsiapali, Olga I., Efthymia Ayfantopoulou, Athanasia Tzourouni, Anna Ofrydopoulou, Sophia Letsiou, and Alexandros Tsoupras. "Unveiling the Utilization of Grape and Winery By-Products in Cosmetics with Health Promoting Properties." Applied Sciences 15, no. 3 (2025): 1007. https://doi.org/10.3390/app15031007.

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Winemaking by-products, such as grape pomace and grape seed oil, provide sustainable and eco-friendly resources for cosmetics and are rich in bioactive compounds like phenolic bioactives, proteins, and lipids (i.e., unsaturated fatty acids, bioactive polar lipids, and carotenoids). These compounds, extracted using advanced techniques such as ultrasound, microwave, and enzyme-assisted methods, exhibit antioxidant, antimicrobial, anti-aging, and anti-inflammatory properties. In vitro and in vivo studies on keratinocytes and fibroblasts demonstrate their efficacy in enhancing skin hydration, elasticity, and UV protection while reducing oxidative stress and inflammation through pathways like SIRT1 and HSP47. Encapsulation techniques further improve their stability and bioavailability. The aim of this review is to investigate in detail the advanced techniques for the extraction of bioactive compounds from winemaking by-products and to evaluate their effectiveness in the isolation of phenolic compounds, proteins, and lipids. At the same time, it focuses on the application of the extracted compounds in the cosmetics industry, highlighting their contribution to products with antioxidant, anti-aging, antimicrobial, and anti-inflammatory properties. Finally, special emphasis is given to encapsulation techniques to improve their stability and bioavailability, with the aim of developing innovative and sustainable cosmetic products.

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Nahum, Victoria, and Abraham J. Domb. "Recent Developments in Solid Lipid Microparticles for Food Ingredients Delivery." Foods 10, no. 2 (2021): 400. http://dx.doi.org/10.3390/foods10020400.

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Health food has become a prominent force in the market place, influencing many food industries to focus on numerous bioactive compounds to reap benefits from its properties. Use of these compounds in food matrices has several limitations. Most of the food bio-additives are sensitive compounds that may quickly decompose in both food and within the gastrointestinal tract. Since most of these bioactives are highly or partially lipophilic molecules, they possess very low water solubility and insufficient dispersibility, leading to poor bioavailability. Thus, various methods of microencapsulation of large number of food bioactives have been studied. For encapsulation of hydrophobic compounds several lipid carriers and lipid platforms have been studied, including emulsions, microemulsions, micelles, liposomes, and lipid nano- and microparticles. Solid lipid particles (SLP) are a promising delivery system, can both deliver bioactive compounds, reduce their degradation, and permit slow and sustained release. Solid lipid particles have important advantages compared to other polymer carriers in light of their simple production technology, including scale up ability, higher loading capacity, extremely high biocompatibility, and usually low cost. This delivery system provides improved stability, solubility in various matrixes, bioavailability, and targeting properties. This article reviews recent studies on microencapsulation of selected bioactive food ingredients in solid lipid-based carriers from a point of view of production methods, characteristics of obtained particles, loading capability, stability, and release profile.

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Günal-Köroğlu, Deniz, Aysenur Betul Bilgin, Gulsah Karabulut, Beyza Saricaoglu, and Esra Capanoglu. "Encapsulation of hydrophobic compounds in yeast cells: methods, characterization, and applications." Exploration of Foods and Foodomics 2, no. 3 (2024): 252–74. http://dx.doi.org/10.37349/eff.2024.00037.

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Encapsulation is a pivotal technique for protecting and enhancing the efficiency of sensitive natural bioactive substances, notably essential oils, vitamins, and phenolic compounds, widely used in foods and nutraceuticals. Critical considerations in selecting encapsulation agents encompass safety, release kinetics, stability, and cost-effectiveness. Yeast cells emerge as versatile carriers distinguished by their low cost, compatibility with biological systems, and eco-friendly degradation properties, accommodating both hydrophilic and hydrophobic bioactive agents. Various yeast strains, including Saccharomyces cerevisiae, Torulopsis lipofera, Cutaneotrichosporon curvatus, Yarrowia lipolytica, and Candida utilis, find utility in microencapsulation. Yeast cell encapsulation relies on the permeation of bioactive agents through yeast cell walls, predominantly composed of mannoproteins and polysaccharides. The encapsulation process includes passive or vacuum-infused diffusion of bioactive compounds inside yeast cells, precise droplet size control, and attractive forces to trap bioactive components within cellular structures. Yeast cells display versatility in various states, whether alive or dead, intact or plasmolyzed. In addition, the loading capacity of hydrophobic bioactives can be increased through chemical pretreatment techniques such as plasmolysis, autolysis, and enzyme hydrolysis, freeing up space within yeast cells by eliminating water-soluble components. In summary, yeast cell encapsulation presents a promising and sustainable technology with diverse applications within the food industry. Yeast cells enhance the stability and controlled release of bioactive compounds, magnifying the efficacy of natural hydrophobic bioactives like curcumin, essential oils, β-carotene, and vitamin D across various food products. This comprehensive review focuses on the encapsulation procedures, influential factors, characterization techniques, and applications, with a pronounced emphasis on hydrophobic materials.

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Bulca, Selda, and Burcu Güvenç. "Süt ve Süt Ürünlerinde Bulunan Biyoaktif Peptitler, Antimikrobiyal Özellikleri ve İnsan Sağlığı Üzerindeki Etkileri." Turkish Journal of Agriculture - Food Science and Technology 8, no. 1 (2020): 158. http://dx.doi.org/10.24925/turjaf.v8i1.158-164.2886.

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In recent years, apart from the nutritional values of foods, functional properties have also gained importance. Bioactive peptides are the fragmentation products of proteins that have a positive effect on human health. Bioactive peptides in cow's milk are released as a result of hydrolysis of milk proteins with proteolytic enzymes. Bioactive peptides have biochemical and physiological properties such as immune regulation, mineral binding, antimicrobial, antihypertensive, opioid, anti-oxidative, anti-ulcerative, antithrombotic, antitumor and apoptosis. In this review, bioactive peptides in milk and milk products and their antimicrobial properties and effects on human health were evaluated.

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Ozuna, César, and Ma Fabiola León-Galván. "Cucurbitaceae Seed Protein Hydrolysates as a Potential Source of Bioactive Peptides with Functional Properties." BioMed Research International 2017 (2017): 1–16. http://dx.doi.org/10.1155/2017/2121878.

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Seeds from Cucurbitaceae plants (squashes, pumpkins, melons, etc.) have been used both as protein-rich food ingredients and nutraceutical agents by many indigenous cultures for millennia. However, relatively little is known about the bioactive components (e.g., peptides) of the Cucurbitaceae seed proteins (CSP) and their specific effects on human health. Therefore, this paper aims to provide a comprehensive review of latest research on bioactive and functional properties of CSP isolates and hydrolysates. Enzymatic hydrolysis can introduce a series of changes to the CSP structure and improve its bioactive and functional properties, including the enhanced protein solubility over a wide range of pH values. Small-sized peptides in CSP hydrolysates seem to enhance their bioactive properties but adversely affect their functional properties. Therefore, medium degrees of hydrolysis seem to benefit the overall improvement of bioactive and functional properties of CSP hydrolysates. Among the reported bioactive properties of CSP isolates and hydrolysates, their antioxidant, antihypertensive, and antihyperglycaemic activities stand out. Therefore, they could potentially substitute synthetic antioxidants and drugs which might have adverse secondary effects on human health. CSP isolates and hydrolysates could also be implemented as functional food ingredients, thanks to their favorable amino acid composition and good emulsifying and foaming properties.

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Kiani, A., N. J. Lakhkar, V. Salih, et al. "Titanium-containing bioactive phosphate glasses." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 370, no. 1963 (2012): 1352–75. http://dx.doi.org/10.1098/rsta.2011.0276.

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The use of biomaterials has revolutionized the biomedical field and has received substantial attention in the last two decades. Among the various types of biomaterials, phosphate glasses have generated great interest on account of their remarkable bioactivity and favourable physical properties for various biomedical applications relating to both hard and soft tissue regeneration. This review paper focuses mainly on the development of titanium-containing phosphate-based glasses and presents an overview of the structural and physical properties. The effect of titanium incorporation on the glassy network is to introduce favourable properties. The biocompatibility of these glasses is described along with recent developments in processing methodologies, and the potential of Ti-containing phosphate-based glasses as a bone substitute material is explored.

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Paudel, Devendra, Bandana Dhungana, Melanie Caffe, and Padmanaban Krishnan. "A Review of Health-Beneficial Properties of Oats." Foods 10, no. 11 (2021): 2591. http://dx.doi.org/10.3390/foods10112591.

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Oat is among the food crops and ancient grains cultivated and consumed worldwide. It is gaining in popularity owing to its nutritional composition and multifunctional benefits of select bioactive compounds. Beta-glucan is an important component of dietary fiber found in oat grains. It is the major active compound in oats with proven cholesterol-lowering and antidiabetic effects. Oats also provide substantial levels of other bioactive compounds such as phenolic acids, tocols, sterols, avenacosides, and avenanthramides. The consumption of oats has been determined to be beneficial for human health by promoting immunomodulation and improving gut microbiota. In addition, oat consumption assists in preventing diseases such as atherosclerosis, dermatitis, and some forms of cancer. While much has been published in relation to oat nutrients and oat fibers and their impact on major diseases, the oat industries and consumers may benefit from greater knowledge and understanding of clinical effects, range of occurrence, distribution, therapeutic doses and food functional attributes of other oat bioactives such as avenanthramides and saponins as well as other anti-inflammatory agents found in the cereal. This review focuses on the various studies relevant to the contribution of the consumption of oats and oat-based products in preventing human diseases and promoting human health.

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Kandylis, Panagiotis, Argyro Bekatorou, Dimitra Dimitrellou, Iris Plioni, and Kanella Giannopoulou. "Health Promoting Properties of Cereal Vinegars." Foods 10, no. 2 (2021): 344. http://dx.doi.org/10.3390/foods10020344.

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Vinegar has been used for its health promoting properties since antiquity. Nowadays, these properties are investigated, scientifically documented, and highlighted. The health benefits of vinegar have been associated with the presence of a variety of bioactive components such as acetic acid and other organic acids, phenolic compounds, amino acids, carotenoids, phytosterols, vitamins, minerals, and alkaloids, etc. These components are known to induce responses in the human body, such as antioxidant, antidiabetic, antimicrobial, antitumor, antiobesity, antihypertensive, and anti-inflammatory effects. The diversity and levels of bioactive components in vinegars depend on the raw material and the production method used. Cereal vinegars, which are more common in the Asia-Pacific region, are usually made from rice, although other cereals, such as millet, sorghum, barley, malt, wheat, corn, rye, oats, bran and chaff, are also used. A variety of bioactive components, such as organic acids, polyphenols, amino acids, vitamins, minerals, alkaloids, melanoidins, butenolides, and specific compounds such as γ-oryzanol, tetramethylpyrazine, γ-aminobutyric acid, etc., have been associated with the health properties of cereal vinegars. In this work, the bioactive components and the related health effects of cereal vinegars are reviewed, and the most recent scientific literature is presented and discussed.

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Viitala, R., M. Jokinen, T. Peltola, K. Gunnelius, and J. B. Rosenholm. "Surface properties of in vitro bioactive and non-bioactive sol–gel derived materials." Biomaterials 23, no. 15 (2002): 3073–86. http://dx.doi.org/10.1016/s0142-9612(02)00017-0.

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Nogueira, Gislaine Ferreira, Rafael Augustus de Oliveira, José Ignacio Velasco, and Farayde Matta Fakhouri. "Methods of Incorporating Plant-Derived Bioactive Compounds into Films Made with Agro-Based Polymers for Application as Food Packaging: A Brief Review." Polymers 12, no. 11 (2020): 2518. http://dx.doi.org/10.3390/polym12112518.

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Plastic, usually derived from non-renewable sources, is among the most used materials in food packaging. Despite its barrier properties, plastic packaging has a recycling rate below the ideal and its accumulation in the environment leads to environmental issues. One of the solutions approached to minimize this impact is the development of food packaging materials made from polymers from renewable sources that, in addition to being biodegradable, can also be edible. Different biopolymers from agricultural renewable sources such as gelatin, whey protein, starch, chitosan, alginate and pectin, among other, have been analyzed for the development of biodegradable films. Moreover, these films can serve as vehicles for transporting bioactive compounds, extending their applicability as bioactive, edible, compostable and biodegradable films. Biopolymer films incorporated with plant-derived bioactive compounds have become an interesting area of research. The interaction between environment-friendly biopolymers and bioactive compounds improves functionality. In addition to interfering with thermal, mechanical and barrier properties of films, depending on the properties of the bioactive compounds, new characteristics are attributed to films, such as antimicrobial and antioxidant properties, color and innovative flavors. This review compiles information on agro-based biopolymers and plant-derived bioactive compounds used in the production of bioactive films. Particular emphasis has been given to the methods used for incorporating bioactive compounds from plant-derived into films and their influence on the functional properties of biopolymer films. Some limitations to be overcome for future advances are also briefly summarized. This review will benefit future prospects for exploring innovative methods of incorporating plant-derived bioactive compounds into films made from agricultural polymers.

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Chatterjee, Cynthia, Stephen Gleddie, and Chao-Wu Xiao. "Soybean Bioactive Peptides and Their Functional Properties." Nutrients 10, no. 9 (2018): 1211. http://dx.doi.org/10.3390/nu10091211.

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Soy consumption has been associated with many potential health benefits in reducing chronic diseases such as obesity, cardiovascular disease, insulin-resistance/type II diabetes, certain type of cancers, and immune disorders. These physiological functions have been attributed to soy proteins either as intact soy protein or more commonly as functional or bioactive peptides derived from soybean processing. These findings have led to the approval of a health claim in the USA regarding the ability of soy proteins in reducing the risk for coronary heart disease and the acceptance of a health claim in Canada that soy protein can help lower cholesterol levels. Using different approaches, many soy bioactive peptides that have a variety of physiological functions such as hypolipidemic, anti-hypertensive, and anti-cancer properties, and anti-inflammatory, antioxidant, and immunomodulatory effects have been identified. Some soy peptides like lunasin and soymorphins possess more than one of these properties and play a role in the prevention of multiple chronic diseases. Overall, progress has been made in understanding the functional and bioactive components of soy. However, more studies are required to further identify their target organs, and elucidate their biological mechanisms of action in order to be potentially used as functional foods or even therapeutics for the prevention or treatment of chronic diseases.

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Rabia, Alghazeer, Abourghiba Taher, Ibrahim Ahmed, and Zreba Esra. "Bioactive properties of some selected Libyan plants." Journal of Medicinal Plants Research 10, no. 6 (2016): 67–76. http://dx.doi.org/10.5897/jmpr2015.5955.

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Zhang, Di, Eveliina Munukka, Leena Hupa, Heimo O. Ylänen, Matti K. Viljanen, and Mikko Hupa. "Factors Controlling Antibacterial Properties of Bioactive Glasses." Key Engineering Materials 330-332 (February 2007): 173–76. http://dx.doi.org/10.4028/www.scientific.net/kem.330-332.173.

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Factors controlling the antibacterial ability of three bioactive glasses were studied by comparing the changes in the SBF during immersion of the glasses with their response to four microorganisms. After immersion of 100 mg/ml fine powder (<45μm) of the glasses in the SBF for 1, 2, 4, 8, 16, 27 and 48 hours, the immersion solutions were filtered and the pH in the bulk solution was measured. Ionic concentrations of Na, K, Ca, Mg, P and Si ions in the immersion solutions were determined by ICP-OES. The antibacterial activity of the glasses showed good correlation with the changes of the pH values in the SBF solutions. No correlation was found between the ionic concentration and the antibacterial ability of the three glasses against the four tested microorganisms. The results suggest that, the antimicrobial effect of the glass powder against the microorganisms tested is mostly dependent on the increase of the pH in the solution to values detrimental for the bacteria growth.

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