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Dissertations / Theses on the topic 'Biological ontology'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Bartol, Jordan Nelson. "'Kind Historicism' & biological ontology." Thesis, University of Leeds, 2015. http://etheses.whiterose.ac.uk/9473/.

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This thesis develops a new theory of natural kinds for the biological world, called ‘Kind Historicism’, and addresses the relationship between natural kind theorizing and scientific reasoning. Applied to natural kinds and individuals in biology, Kind Historicism provides an ontology of the biological world. Discussions of biological ontology have struggled to balance insights from scientific practice with tools from analytic philosophy, metaphysics, and ontology. Ontological questions and practical/epistemic questions are often entangled. This thesis separates the two enquires, explaining why

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2

Mossley, David John. "Biological being : philosophical issues in scientific realism, experiments and (dis)unity." Thesis, Durham University, 1997. http://etheses.dur.ac.uk/4754/.

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The biological sciences are changing the ways in which we understand ourselves Biological Being is a philosophical exploration of biology, mapping some of the features of the field that make it so important in generating these changes Two central themes are at the heart of this exploration: biology is a science that should be grasped from a realist position, and it is a science that reveals a disunified, pluralistic world of kinds of things. After an introduction of some the issues involved, in three substantial chapters these themes are unpacked and analysed. The first major chapter is about

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3

Davidson, Christopher. "Applying database and ontology design techniques to a NASA biological research repository." [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0000922.

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4

Feltrin, Erika. "Contribution to OBO ontologies and application of structured vocabularies for data integration and biological reasoning." Doctoral thesis, Università degli studi di Padova, 2008. http://hdl.handle.net/11577/3426373.

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As the amount of accessible biological data is growing exponentially, it is becoming harder and harder to extract the biological knowledge contained in thousands of databases. Biomedical scientists collect facts, often recording them in natural language, and then use their knowledge to make inferences about as yet uncharacterised observations. Therefore, to make the best use of biological databases and the knowledge they contain, different kinds of information from diï¬€erent sources must be integrated in ways that make sense to the scientific community. The Gene Ontology (GO) and other biomed

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5

Kim, Wooyoung. "Innovative Algorithms and Evaluation Methods for Biological Motif Finding." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/cs_diss/63.

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Biological motifs are defined as overly recurring sub-patterns in biological systems. Sequence motifs and network motifs are the examples of biological motifs. Due to the wide range of applications, many algorithms and computational tools have been developed for efficient search for biological motifs. Therefore, there are more computationally derived motifs than experimentally validated motifs, and how to validate the biological significance of the ‘candidate motifs’ becomes an important question. Some of sequence motifs are verified by their structural similarities or their functional roles i

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6

Pohl, Matin. "Using an ontology to enhance metabolic or signaling pathway comparisions by biological and chemical knowledge." Thesis, University of Skövde, School of Humanities and Informatics, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-32.

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<p>Motivation:</p><p>As genome-scale efforts are ongoing to investigate metabolic networks of miscellaneous organisms the amount of pathway data is growing. Simultaneously an increasing amount of gene expression data from micro arrays becomes available for reverse engineering, delivering e.g. hypothetical regulatory pathway data. To avoid outgrowing of data and keep control of real new informations the need of analysis tools arises. One vital task is the comparison of pathways for detection of similar functionalities, overlaps, or in case of reverse engineering, detection of known data corrobo

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7

REHMAN, HAFEEZ UR. "Integration and Analysis of Heterogeneous Biological Data." Doctoral thesis, Politecnico di Torino, 2014. http://hdl.handle.net/11583/2537092.

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We live in the era of networks. The power of networks is the most fundamental driving force behind the machinery of life. Living bodies stay alive through complex inter-regulations of biochemical networks and information flows through these networks with such a great intensity and complexity that it exceeds anything that the human ingenuity has been able to spawn so far. Due to this overwhelming complexity we have begun to see a rapid rise in studies aimed at explaining the fundamental concepts and hidden properties of such complex systems. This thesis provides a strong foundation of using net

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8

He, Xin. "A semi-automated framework for the analytical use of gene-centric data with biological ontologies." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/25505.

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Motivation Translational bioinformatics(TBI) has been defined as ‘the development and application of informatics methods that connect molecular entities to clinical entities’ [1], which has emerged as a systems theory approach to bridge the huge wealth of biomedical data into clinical actions using a combination of innovations and resources across the entire spectrum of biomedical informatics approaches [2]. The challenge for TBI is the availability of both comprehensive knowledge based on genes and the corresponding tools that allow their analysis and exploitation. Traditionally, biological r

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9

Seth, Pawan. "STUDY OF THE RELATIONSHIP BETWEEN Mus musculus PROTEIN SEQUENCES AND THEIR BIOLOGICAL FUNCTIONS." University of Akron / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=akron1176736255.

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10

Bahurek, Tomáš. "Dotazovací jazyk pro databáze biologických dat." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2015. http://www.nusl.cz/ntk/nusl-234998.

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With rising amount of biological data, biological databases are becoming more important each day. Knowledge discovery (identification of connections that were unknown at the time of data entry) is an essential aspect of these databases. To gain knowledge from these databases one has to construct complicated SQL queries, which requires advanced knowledge of SQL language and used database schema. Biologists usually don't have this knowledge, which creates need for tool, that would offer more intuitive interface for querying biological databases. This work proposes ChQL, an intuitive query langua

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11

Hagen, Matthew. "Biological and clinical data integration and its applications in healthcare." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/54267.

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Answers to the most complex biological questions are rarely determined solely from the experimental evidence. It requires subsequent analysis of many data sources that are often heterogeneous. Most biological data repositories focus on providing only one particular type of data, such as sequences, molecular interactions, protein structure, or gene expression. In many cases, it is required for researchers to visit several different databases to answer one scientific question. It is essential to develop strategies to integrate disparate biological data sources that are efficient and seamless to

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12

GUDIVADA, RANGA CHANDRA. "DISCOVERY AND PRIORITIZATION OF BIOLOGICAL ENTITIES UNDERLYING COMPLEX DISORDERS BY PHENOME-GENOME NETWORK INTEGRATION." University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1195161740.

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13

Sanavia, Tiziana. "Biomarker lists stability in genomic studies: analysis and improvement by prior biological knowledge integration into the learning process." Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3422197.

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The analysis of high-throughput sequencing, microarray and mass spectrometry data has been demonstrated extremely helpful for the identification of those genes and proteins, called biomarkers, helpful for answering to both diagnostic/prognostic and functional questions. In this context, robustness of the results is critical both to understand the biological mechanisms underlying diseases and to gain sufficient reliability for clinical/pharmaceutical applications. Recently, different studies have proved that the lists of identified biomarkers are poorly reproducible, making the validation of bi

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14

Edelmann, Jonathan B. "When two worldviews meet : a dialogue between the Bhagavata Purana and contemporary biological theory." Thesis, University of Oxford, 2008. http://ora.ox.ac.uk/objects/uuid:d5e04b73-8b28-4950-b1bc-10416ea04504.

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Over the past thirty years, academic dialogues on the relationships between the sciences and religions have flourished, albeit primarily within Judeo-Christian historical, theological and philosophical contexts. Can a Hindu tradition be brought into this dialogue? The Bhagavata Purana is one of the most well-known sacred texts of India, and biology, Darwinism in particular, has become one of the most spirited areas of the science and religion dialogue in academia, as well as in the popular media. This thesis examines the possibility, scope and foundational topics involved in a dialogue between

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15

Marpuri, ReddySalilaja. "Evaluation of Annotation Performances between Automated and Curated Databases of E.COLI Using the Correlation Coefficient." TopSCHOLAR®, 2009. http://digitalcommons.wku.edu/theses/94.

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This project compared the performance of the correlation coefficient to show similarities in annotations between a predictive automated bacterial annotation database and the curated EcoCyc database. EcoCyc is a conservative multidimensional annotation system that is exclusively based on experimentally validated findings by over 15,000 publications. The automated annotation system, used in the comparison was BASys. It is often used as a first pass annotation tool that tries to add as many annotations as possible by drawing upon over 30 information sources. Gene ontology served as one basis of c

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16

Bock, Jürgen [Verfasser]. "Ontology Alignment using Biologically-inspired Optimisation Algorithms / Jürgen Bock." Karlsruhe : KIT Scientific Publishing, 2013. http://www.ksp.kit.edu.

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Bock, Jürgen [Verfasser], and R. [Akademischer Betreuer] Studer. "Ontology Alignment using Biologically-inspired Optimisation Algorithms / Jürgen Bock. Betreuer: R. Studer." Karlsruhe : KIT-Bibliothek, 2012. http://d-nb.info/1024729532/34.

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Palazzi, Daniele Cristina. "QDAontology – abordagem para o desenvolvimento de ontologias em e-science: um estudo de caso em biologia." Universidade Federal de Juiz de Fora (UFJF), 2010. https://repositorio.ufjf.br/jspui/handle/ufjf/4406.

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Submitted by isabela.moljf@hotmail.com (isabela.moljf@hotmail.com) on 2017-05-04T15:40:50Z No. of bitstreams: 1 danielecristinapalazzi.pdf: 10986138 bytes, checksum: 0dc14af800b34e649fec5c397c87cc25 (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-05-17T13:31:34Z (GMT) No. of bitstreams: 1 danielecristinapalazzi.pdf: 10986138 bytes, checksum: 0dc14af800b34e649fec5c397c87cc25 (MD5)<br>Made available in DSpace on 2017-05-17T13:31:34Z (GMT). No. of bitstreams: 1 danielecristinapalazzi.pdf: 10986138 bytes, checksum: 0dc14af800b34e649fec5c397c8

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Rahm, Jonas. "Biologically plausible visual representation of modular decomposition." Thesis, University of Skövde, School of Humanities and Informatics, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-953.

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<p>Modular decompositions of protein interaction networks can be used to identify modules of cooperating proteins. The biological plausibility off these modules might be questioned though. This report describes how a modular decomposition can be completed with semantic information in the visual representation. Possible methods for creating modules of functionally related proteins are also proposed in this work. The results show that such modules, with advantage can be combined with modules from a graph decomposition, to find proteins that are likely to cooperate to perform certain functions in

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Repchevskiy, Dmitry. "Ontology based data integration in life sciences." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/386411.

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The aim of this thesis is to develop standard and practical approaches for the semantic integration of biological data and services. The thesis considers various scenarios where ontologies may benefit bioinformatics web services development, integration and provenance. In spite of the broad use of ontologies in biology, their usage is usually limited to a definition of taxonomic hierarchies. This thesis examines the utility of ontologies for data integration in context of semantic web services development. The biological datatypes ontologies are very valuable for the data integration, especial

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21

Korkmaz, Gulberal Kircicegi Yoksul. "Mining Microarray Data For Biologically Important Gene Sets." Phd thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614266/index.pdf.

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Microarray technology enables researchers to measure the expression levels of thousands of genes simultaneously to understand relationships between genes, extract pathways, and in general understand a diverse amount of biological processes such as diseases and cell cycles. While microarrays provide the great opportunity of revealing information about biological processes, it is a challenging task to mine the huge amount of information contained in the microarray datasets. Generally, since an accurate model for the data is missing, first a clustering algorithm is applied and then the resulting

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22

Jimeno, Yepes Antonio José. "Ontology refinement for improved information retrieval in the biomedical domain." Doctoral thesis, Universitat Jaume I, 2009. http://hdl.handle.net/10803/384552.

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Este trabajo de tesis doctoral se centra en el uso de ontologías de dominio y su refinamiento enfocado a la recuperación de la información. El dominio seleccionado ha sido el de la Biomedicina, que dispone de una extensa colección de resúmenes en la base de datos Medline y recursos que facilitan la creación de ontologías muy extensas, tales como MeSH o UMLS. En este trabajo se ha desarrollado también un modelo de formulación de consulta que permite relacionar un modelo de documento con una ontología dentro de los modelos de lenguaje. Además hemos desarrollado un algoritmo que permite mejorar

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23

NOTARO, MARCO. "HIERARCHICAL ENSEMBLE METHODS FOR ONTOLOGY-BASED PREDICTIONS IN COMPUTATIONAL BIOLOGY." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/606185.

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L'annotazione standardizzata di entità biologiche, quali geni e proteine, ha fortemente promosso l'organizzazione dei concetti biologici in vocabolari controllati, cioè ontologie che consentono di indicizzare in modo coerente le relazioni tra le diverse classi funzionali organizzate secondo una gerarchia predefinita. Esempi di ontologie biologiche in cui i termini funzionali sono strutturati secondo un grafo diretto aciclico (DAG) sono la Gene Ontology (GO) e la Human Phenotype Ontology (HPO). Tali tassonomie gerarchiche vengono utilizzate dalla comunità scientifica rispettivamente per sistema

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24

Isik, Zerrin, Tulin Ersahin, Volkan Atalay, Cevdet Aykanat, and Rengul Cetin-Atalay. "A signal transduction score flow algorithm for cyclic cellular pathway analysis, which combines transcriptome and ChIP-seq data." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-138982.

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Determination of cell signalling behaviour is crucial for understanding the physiological response to a specific stimulus or drug treatment. Current approaches for large-scale data analysis do not effectively incorporate critical topological information provided by the signalling network. We herein describe a novel model- and data-driven hybrid approach, or signal transduction score flow algorithm, which allows quantitative visualization of cyclic cell signalling pathways that lead to ultimate cell responses such as survival, migration or death. This score flow algorithm translates signalling

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Farias, Luciana Fortes. "SISTEMA MULTIAGENTE PARA MONITORAMENTO AMBIENTAL DO COMPLEXO PORTUÁRIO DA ILHA DE SÃO LUÍS-MARANHÃO." Universidade Federal do Maranhão, 2009. http://tedebc.ufma.br:8080/jspui/handle/tede/423.

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Made available in DSpace on 2016-08-17T14:53:06Z (GMT). No. of bitstreams: 1 Luciana Fortes Farias.pdf: 24712291 bytes, checksum: d8760f57e945d0cde298c31a44b38539 (MD5) Previous issue date: 2009-11-04<br>This work is discussed the conceptual model of a multi-agent system for environmental monitoring with the use of biomarkers of aquatic organisms present in the port complex of São Luís-Maranhão-Brasil, second most important in the country in cargo handling. Located in the São Marcos Bay, this complex have an estuarine ecosystems which have suffered attacks in the current process of economi

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26

Meluzzi, Marco. "Metodi ed algoritmi di data science per la scoperta di nuove funzioni biologiche di geni: implementazione e analisi sperimentale." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2019.

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Comprendere il modo in cui i singoli geni contribuiscono alla biologia di un organismo, individuandone le specifiche funzioni, è uno degli obiettivi primari della ricerca biomedica per lo sviluppo di nuovi farmaci e terapie personalizzate. Negli ultimi anni metodi ed algoritmi di Data Science si sono rivelati fondamentali in ambito genomico, dando un contributo importante alla ricerca scientifica tradizionale, molto spesso limitata da fattori etici, di tempo e di costo. Ciò è reso possibile anche grazie alla nascita di banche dati specializzate, tra cui Gene Ontology, il cui obiettivo è quello

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Chizzola, Valentina <1976&gt. "La filosofia della biologia come ontologia del vivente: il concetto di organismo nel pensiero di Hans Jonas." Doctoral thesis, Università Ca' Foscari Venezia, 2007. http://hdl.handle.net/10579/74.

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Giannini, Andrea. "Individuazione di Nuove Funzioni Biologiche di Geni mediante Transfer Learning Inter-Organismo con Reti Neurali Autoencoder." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/17018/.

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La genomica è la disciplina che si occupa della struttura, sequenza, funzione ed evoluzione del genoma, cioè dell’informazione genetica contenuta nel DNA presente nelle cellule di una particolare specie. Avendo a disposizione enormi quantità di dati per l'uomo diventa difficile poterli analizzare tutti e riuscire fare deduzioni su di essi. Perciò fin dai primi anni di ricerca, in questa branca della biologia, si è resa fondamentale l'informatica per l'elaborazione e la visualizzazione dei dati che produce, tanto da poter affermare che si basa sulla bioinformatica. Con l'accrescere dei dat

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Isik, Zerrin, Tulin Ersahin, Volkan Atalay, Cevdet Aykanat, and Rengul Cetin-Atalay. "A signal transduction score flow algorithm for cyclic cellular pathway analysis, which combines transcriptome and ChIP-seq data." Royal Society of Chemistry, 2012. https://tud.qucosa.de/id/qucosa%3A27799.

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Determination of cell signalling behaviour is crucial for understanding the physiological response to a specific stimulus or drug treatment. Current approaches for large-scale data analysis do not effectively incorporate critical topological information provided by the signalling network. We herein describe a novel model- and data-driven hybrid approach, or signal transduction score flow algorithm, which allows quantitative visualization of cyclic cell signalling pathways that lead to ultimate cell responses such as survival, migration or death. This score flow algorithm translates signalling

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Moraes, Marilda Schiller de. "Coaching ontológico: uma contribuição à gestão hospitalar." Pontifícia Universidade Católica de São Paulo, 2015. https://tede2.pucsp.br/handle/handle/1141.

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Made available in DSpace on 2016-04-25T16:44:44Z (GMT). No. of bitstreams: 1 Marilda Schiller de Moraes.pdf: 2077674 bytes, checksum: 85683f79e158bd4fe193bcf41b45adf2 (MD5) Previous issue date: 2015-09-17<br>This study s main goal is to identify how the use of Ontological Coaching, based on the Ontology of Language, can facilitate communication and assist in building healthy and productive environments within companies. In the universe of organizations the communication issue has great importance, because it is through the instructions and exchange of informations that are developed all the

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Matos, Ely Edison da Silva. "CelOWS: um framework baseado em ontologias com serviços web para modelagem conceitual em biologia sistêmica." Universidade Federal de Juiz de Fora (UFJF), 2008. https://repositorio.ufjf.br/jspui/handle/ufjf/3560.

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Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-03-07T12:42:38Z No. of bitstreams: 1 elyedsondasilvamatos.pdf: 1113400 bytes, checksum: 983068af705f65ab80cd37df7d39f34c (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-03-07T15:04:38Z (GMT) No. of bitstreams: 1 elyedsondasilvamatos.pdf: 1113400 bytes, checksum: 983068af705f65ab80cd37df7d39f34c (MD5)<br>Made available in DSpace on 2017-03-07T15:04:38Z (GMT). No. of bitstreams: 1 elyedsondasilvamatos.pdf: 1113400 bytes, checksum: 983068af705f65ab80cd37df7d39f34c (MD5) Previous is

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Vashisht, S. "COMPUTATIONAL APPROACHES IN THE ESTIMATION AND ANALYSIS OF TRANSCRIPTS DIFFERENTIAL EXPRESSION AND SPLICING: APPLICATION TO SPINAL MUSCULAR ATROPHY." Doctoral thesis, Università degli Studi di Milano, 2017. http://hdl.handle.net/2434/470076.

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Spinal Muscular Atrophy (SMA) is among the most common genetic neurological diseases that cause infant mortality. SMA is caused by deletion or mutations in the survival motor neuron 1 gene (SMN1), which are expected to generate alterations in RNA transcription, or splicing and most importantly reductions in mRNA transport within the axons of motor neurons (MNs). SMA ultimately results in the selective degeneration of MNs in spinal cord, but the underlying reason is still not clear entirely. The aim of this study is to investigate splicing abnormalities in SMA, and to identify genes presenting

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Hudelot, Céline. "Towards a Cognitive Vision Platform for Semantic Image Interpretation; Application to the Recognition of Biological Organisms." Phd thesis, Université de Nice Sophia-Antipolis, 2005. http://tel.archives-ouvertes.fr/tel-00328034.

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Ces travaux de thèse ont pour but de faire des avancées dans le domaine de la vision cognitive en proposant une plate-forme fonctionnelle et logicielle pour le problème complexe de l'interprétation sémantique d'images. Nous nous sommes focalisés sur la proposition de solutions génériques et indépendantes de toute application. Plus qu'une solution à un problème spécifique, la plate-forme proposée est une architecture minimale qui fournit des outils réutilisables pour la conception de systèmes d'interprétation sémantique d'images.<br />Le problème de l'interprétation sémantique d'images est un p

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Dieli, Anna Maria. "La hiérarchie des individus biologiques : problèmes ontologiques et épistémologiques." Thesis, Paris 1, 2018. http://www.theses.fr/2018PA01H203/document.

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Au cours de cette thèse on développera l'hypothèse que l'individu biologique soit une unité fonctionnelle hiérarchiquement organisée : une définition qui correspond à l'ontologie des systèmes biologiques et influence la pratique de la biologie. Le but de cette thèse est de démontrer que l'organisation des entités en niveaux n'est pas une question purement méthodologique : le fait d'avoir des Individus à plusieurs niveaux fait partie de l'ontologie des systèmes biologiques. Le point de départ de la thèse c'est le constat qu'il y a des individus biologiques à plusieurs niveaux : c'est-à-dire des

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Dönitz, Jürgen. "Development and application of ontologies for biological applications." Thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-0028-86B9-B.

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Dippold, Mindi M. "A Biological and Bioinformatics Ontology for Service Discovery and Data Integration." Thesis, 2006. http://hdl.handle.net/1805/621.

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Submitted to the faculty of Indiana University in partial fulfillment of the requirements for the degree Masters of Science in the School of Informatics Indiana University December 2005<br>This project addresses the need for an increased expressivity and robustness of ontologies already supporting BACIIS and SIBIOS, two systems for data and service integration in the life sciences. The previous ontology solutions as global schema and facilitator of service discovery sustained the purposes for which they were built to provide, but were in need of updating in order to keep up with more recent s

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Köhler, Jacob [Verfasser]. "SEMEDA (semantic meta database) : ontology based semantic integration of biological databases / von Jacob Köhler." 2003. http://d-nb.info/968863019/34.

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Fruzangohar, Mario. "Biomedical literature mining." Thesis, 2014. http://hdl.handle.net/2440/85201.

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Thousands of biomedical articles are published every year containing many newly discovered biological interactions and functions. Manually reading and classifying this information is a difficult and laborious task. Literature mining contains mechanisms and tools to automate the process of extracting biological relationships, storing them in biological databases and finally analyse and present them in a biological meaningful way. In the first stage of literature mining, articles are parsed and get segmented, sentences separated, tokenized and finally annotated by part of speech tags (POS). POS

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O'Neill, Kieran. "Relieving the cognitive load of constructing molecular biological ontology based queries by means of visual aids." Thesis, 2007. http://hdl.handle.net/10413/539.

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The domain of molecular biology is complex and vast. Bio-ontologies and information visualisation have arisen in recent years as means to assist biologists in making sense of this information. Ontologies can enable the construction of conceptual queries, but existing systems to do this are too technical for most biologists. OntoDas, the software developed as part of this thesis work, demonstrates how the application of techniques from information visualisation and human computer interaction can result in software which enables biologists to construct conceptual queries.<br>Thesis (M.Comp.Sc.)-

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CAFFO, LEONARDO. "Apparato umano: un’ontologia sociale incarnata." Doctoral thesis, 2015. http://hdl.handle.net/2318/158545.

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The contemporary debate on social ontology (Gallotti and Michael 2014) is largely aimed at the ontological definition of social entities and at the definition of the conditions of possibility for the representation of such objects. The main objective of any project of social ontology, therefore, has to be rooted in understanding what social objects are, that is, in finding the exact location of social objects is in a hypothetical "catalogue of the world" (Laycock 2011). In the perspective of the project "Human Apparatuses" (hereafter HA), social objects are understood as socially constructed b

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Mott, Isabela. "Investigating semantic similarity for biomedical ontology alignment." Master's thesis, 2017. http://hdl.handle.net/10451/31946.

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Tese de mestrado, Bioinformática e Biologia Computacional (Bioinformática) Universidade de Lisboa, Faculdade de Ciências, 2017<br>A heterogeneidade dos dados biomédicos e o crescimento exponencial da informação dentro desse domínio tem levado à utilização de ontologias, que codificam o conhecimento de forma computacionalmente tratável. O desenvolvimento de uma ontologia decorre, em geral, com base nos requisitos da equipa que a desenvolve, podendo levar à criação de ontologias diferentes e potencialmente incompatíveis por várias equipas de investigação. Isto implica que as várias ontologias ex

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Łabaj, Wojciech. "Konstrukcja i adnotacje sygnatur genowych na bazie eksperymentów porównawczych uzyskiwanych technikami wysokoprzepustowymi w biologii molekularnej." Rozprawa doktorska, 2019. https://repolis.bg.polsl.pl/dlibra/docmetadata?showContent=true&id=68236.

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Łabaj, Wojciech. "Konstrukcja i adnotacje sygnatur genowych na bazie eksperymentów porównawczych uzyskiwanych technikami wysokoprzepustowymi w biologii molekularnej." Rozprawa doktorska, 2019. https://delibra.bg.polsl.pl/dlibra/docmetadata?showContent=true&id=68236.

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Martins, Pedro de Almeida. "Previsão da localização subcelular de proteínas humanas com base em aprendizagem automática." Master's thesis, 2017. http://hdl.handle.net/10451/27610.

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Tese de mestrado, Bioinformática e Biologia Computacional (Bioinformática) Universidade de Lisboa, Faculdade de Ciências, 2017<br>Conhecer a localização subcelular de um dado produto génico (i.e., onde a proteína codificada pelo gene está localizada) é particularmente importante para a anotação funcional das proteínas. Para lidar com o aumento exponencial do número de proteínas descobertas recentemente, foram desenvolvidos métodos computacionais capazes de prever a localização subcelular de proteínas. Uma vez que as proteínas localizadas em determinados compartimentos intracelulares possuem ca

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Sousa, Rita Isabel Torres de. "Evolving meaning: using genetic programming to learn similarity perspectives for mining biomedical data." Master's thesis, 2019. http://hdl.handle.net/10451/39550.

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Tese de mestrado, Bioinformática e Biologia Computacional, Universidade de Lisboa, Faculdade de Ciências, 2019<br>Nos últimos anos, as ontologias biomédicas tornaram-se fundamentais para descrever o conhecimento biológico na forma de grafos de conhecimento. Consequentemente, foram propostas várias abordagens de mineração de dados que tiram partido destes grafos de conhecimento. Estas abordagens baseiam-se em representações vetoriais que podem não capturar toda a informação semântica subjacente aos grafos. Uma abordagem alternativa consiste em utilizar a semelhança semântica como representação

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