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Relevant bibliographies by topics / Catharanthine

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Journal articles

Academic literature on the topic 'Catharanthine'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Catharanthine"

1

Keglevich, András, Szabolcs Mayer, Réka Pápai, et al. "Attempted Synthesis of Vinca Alkaloids Condensed with Three-Membered Rings." Molecules 23, no. 10 (2018): 2574. http://dx.doi.org/10.3390/molecules23102574.

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Our successful work for the synthesis of cyclopropanated vinblastine and its derivatives by the Simmons–Smith reaction was followed to build up further three-membered rings into the 14,15-position of the vindoline part of the dimer alkaloid. Halogenated 14,15-cyclopropanovindoline was prepared by reactions with iodoform and bromoform, respectively, in the presence of diethylzinc. Reactions of dichlorocarbene with vindoline resulted in the 10-formyl derivative. Unexpectedly, in the case of the dimer alkaloids vinblastine and vincristine, the rearranged products containing an oxirane ring in the

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2

Zhu, Jianhua, Shuijie He, Pengfei Zhou, et al. "Eliciting Effect of Catharanthine on the Biosynthesis of Vallesiachotamine and Isovallesiachotamine in Catharanthus roseus Cambial Meristematic Cells." Natural Product Communications 13, no. 5 (2018): 1934578X1801300. http://dx.doi.org/10.1177/1934578x1801300508.

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Vallesiachotamine and isovallesiachotamine are pharmacologically active monoterpene indole alkaloids produced by Catharanthus roseus. However, the biosynthetic pathway for these two alkaloids has not been characterized. The results of our experiments demonstrated that catharanthine induced the biosynthesis of vallesiachotamine and isovallesiachotamine in C. roseus cambial meristematic cells (CMCs) in a time- and dosage-dependent manner. The highest yields of vallesiachotamine and isovallesiachotamine (i.e., 1.49 mg l−1 and 1.08 mg l−1, respectively) were observed in CMCs treated with 10 mg cat

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3

Raucher, Stanley, and Brian L. Bray. "Total synthesis of (.+-.)-catharanthine." Journal of Organic Chemistry 50, no. 17 (1985): 3236–37. http://dx.doi.org/10.1021/jo00217a052.

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4

Moisan, Lionel, Pierre Thuéry, Marc Nicolas, Eric Doris, and Bernard Rousseau. "Formal Synthesis of (+)-Catharanthine." Angewandte Chemie International Edition 45, no. 32 (2006): 5334–36. http://dx.doi.org/10.1002/anie.200601307.

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5

Moisan, Lionel, Pierre Thuéry, Marc Nicolas, Eric Doris, and Bernard Rousseau. "Formal Synthesis of (+)-Catharanthine." Angewandte Chemie 118, no. 32 (2006): 5460–62. http://dx.doi.org/10.1002/ange.200601307.

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6

Pandiangan, Dingse. "Peningkatan Produksi Katarantin Melalui Teknik Elisitasi Pada Kultur Agregat Sel Catharanthus roseus." JURNAL ILMIAH SAINS 15, no. 1 (2011): 140. http://dx.doi.org/10.35799/jis.11.2.2011.178.

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ABSTRAK Penelitian ini bertujuan untuk optimasi dan peningkatan produksi antikanker katarantin khususnya elisitasi. Tujuan praktisnya adalah untuk mengetahui pertumbuhan kalus agregat sel C. roseus yang diberi elisitor, menemukan kurva tumbuh S. cerevisiae dan bahan elisitor, menemukan kandungan katarantin pada agregat sel dan medium perlakuan dan menemukan waktu panen perlakuan elisitasi yang menghasilkan kandungan katarantin yang paling tinggi. Dari hasil penelitian ini diharapkan dapat dihasilkan suatu informasi mengenai peningkatan katarantin yang dihasilkan (diproduksi) secara kultur (in

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7

Alehashem, Maryam Sadat, Chuan-Gee Lim, and Noel F. Thomas. "The radical cation mediated cleavage of catharanthine leading to the vinblastine type alkaloids: implications for total synthesis and drug design." RSC Advances 6, no. 22 (2016): 18002–25. http://dx.doi.org/10.1039/c5ra23074h.

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8

Pandya, Prateek, Surendra P. Gupta, Kumud Pandav, Ritu Barthwal, B. Jayaram, and Surat Kumar. "DNA Binding Studies of Vinca Alkaloids: Experimental and Computational Evidence." Natural Product Communications 7, no. 3 (2012): 1934578X1200700. http://dx.doi.org/10.1177/1934578x1200700308.

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Fluorescence studies on the indole alkaloids vinblastine sulfate, vincristine sulfate, vincamine and catharanthine have demonstrated the DNA binding ability of these molecules. The binding mode of these molecules in the minor groove of DNA is non-specific. A new parameter of the purine-pyrimidine base sequence specificty was observed in order to define the non-specific DNA binding of ligands. Catharanthine had shown ‘same’ pattern of ‘Pu-Py’ specificity while evaluating its DNA binding profile. The proton resonances of a DNA decamer duplex were assigned. The models of the drug:DNA complexes we

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9

Raucher, Stanley, Brian L. Bray, and Ross F. Lawrence. "Synthesis of (.+-.)-catharanthine, (+)-anhydrovinblastine, and (-)-anhydrovincovaline." Journal of the American Chemical Society 109, no. 2 (1987): 442–46. http://dx.doi.org/10.1021/ja00236a023.

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10

Sundberg, Richard J., Phyllis J. Hunt, Patrice Desos, and Kumar G. Gadamasetti. "Oxidative fragmentation of catharanthine by dichlorodicyanoquinone." Journal of Organic Chemistry 56, no. 5 (1991): 1689–92. http://dx.doi.org/10.1021/jo00005a007.

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