Relevant bibliographies by topics / Chiral separation; HPLC; chirální separace

Contents

  1. Dissertations / Theses

Academic literature on the topic 'Chiral separation; HPLC; chirální separace'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Chiral separation; HPLC; chirální separace.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Dissertations / Theses on the topic "Chiral separation; HPLC; chirální separace"

1

Kučerová, Gabriela. "Chirální separace nově syntetizovaných aminokyselin metodou HPLC." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-323820.

Full text
Abstract:
The aim of this work was to develop and to optimize HPLC method for enantioseparation of newly synthesized derivatives of amino acids. The set of these analytes contained four N- blocked derivatives of D,L-Phenylalanine, three N-unblocked derivatives of D,L- Phenylalanine, , one methylated derivative of D,L-Tyrosine and D,L-Tyrosine. Two separation modes i.e. reversed phase and polar-organic modes and two columns i.e. Chirobiotic® T and Chirobiotic® T2 were used. Chiral stationary phases of these columns were composed of macrocyclic antibiotic teicoplanin coated on silica gel support. As mobil
APA, Harvard, Vancouver, ISO, and other styles
2

Vozka, Jiří. "Charakterizace nových chirálních separačních systémů pro použití v HPLC." Doctoral thesis, 2014. http://www.nusl.cz/ntk/nusl-332545.

Full text
Abstract:
The dissertation thesis is focused on the physico-chemical characterization of interaction mechanisms of chiral stationary phases based on derivatized cyclofructans. Correct interpretation of retention and enantiodiscrimination processes substantially facilitates the development and optimization of new enantioselective methods using cyclofructan-based chiral stationary phases. At first, the interaction mechanisms of three commercially available cyclofructan-based stationary phases were studied in normal-phase mode of liquid chromatography. Namely, systems using chiral stationary phases based o
APA, Harvard, Vancouver, ISO, and other styles
3

Novák, Martin. "Optimalizace chromatografických podmínek pro chirální separaci biologicky aktivních látek." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-388087.

Full text
Abstract:
Charles University, Faculty of Pharmacy in Hradec Králové Department of: Pharmaceutical Chemistry and Pharmaceutical Analysis Student: Bc. Martin Novák Supervisor: doc. PharmDr. Radim Kučera, Ph.D. Consultant: Mgr. et Mgr. Rafael Doležal, Ph.D. Title of diploma thesis: Optimization of chromatographic parameters for chiral separation of biologically active compounds. The diploma thesis was focused on the development of a HPLC-UV method for the determination of K 1277 enantiomers of systematic name N-(2-((6-chloro-1,2,3,4-tetra- hydroacridin-9-yl)amino)hexyl-2-amino-3-(1H-indole-3-yl) propylamid
APA, Harvard, Vancouver, ISO, and other styles
4

Landl, David. "Chirální separace biologicky aktivních látek v chromatografii." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-434112.

Full text
Abstract:
- 4 - Abstract in English This diploma thesis is focused on the evaluation and comparison of the enantioselective potential of two columns CHIRAL ART Amylose-SA and CDShell-RSP using a set of 29 chiral drugs in high performance liquid chromatography. The separations of enantiomers were performed in three modes: reversed-phase, normal-phase, and polar- organic mode. The CHIRAL ART Amylose-SA column was tested in normal-phase mode, the CDShell-RSP column in reversed-phase and polar-organic modes. The CHIRAL ART Amylose-SA column contains amylose tris(3,5- dimethylphenylcarbamate) immobilized on
APA, Harvard, Vancouver, ISO, and other styles
5

Marvalová, Jana. "Využití HPLC v chirálních separacích VI." Master's thesis, 2021. http://www.nusl.cz/ntk/nusl-446152.

Full text
Abstract:
Charles University Faculty of Pharmacy in Hradec Králové Department: Department of Pharmaceutical chemistry and Pharmaceutical analysis Candidate: Jana Marvalová Supervisor: doc. PharmDr. Radim Kučera, PhD. Title of Thesis: The employment of HPLC in field of chiral separations VI. Boron clusters are synthetically prepared substances that are being intensively studied in connection with Boron Neutron Capture Therapy, the substitution of phenyl rings of molecules of already known drugs and as potential inhibitors of HIV protease. Boron clusters are symmetric molecules, however, by endo- or exo-s
APA, Harvard, Vancouver, ISO, and other styles
6

Burda, Jakub. "Využití HPLC v chirálních separacích V." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-411572.

Full text
Abstract:
Charles University Faculty of Pharmacy in Hradec Králové Department: Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Candidate: Jakub Burda Supervisor: doc. PharmDr. Radim Kučera, Ph.D. Title of Thesis: The employment of HPLC in the field of chiral separations V. Continuously growing requirements of regulatory authorities for the quality and safety of medicines put a high pressure on manufacturers. Last decades are marked by optically pure drugs, whose developement goes hand in hand with developement of chiral syntheses and separations. The most used method in the field of s
APA, Harvard, Vancouver, ISO, and other styles
7

Plecitá, Denisa. "Chirální stacionární fáze na bázi celulosy pro reverzní HPLC." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-338785.

Full text
Abstract:
This diploma thesis is focused on the comparison of enantioselective potential of chiral stationary phases based on derivatized cellulose by high performance liquid chromatography (HPLC). Polysaccharide - based chiral stationary phases are suitable choice for enantioseparation of various chiral compounds. In this work Chiralpak IB column containing cellulose tris(3,5-dimethylphenylcarbamate) selector immobilized onto silica gel and Chiralpak IC column containing cellulose tris(3,5- dichlorophenylcarbamate) selector immobilized onto silica gel were used. Their ability of enantioseparation was t
APA, Harvard, Vancouver, ISO, and other styles
8

Procházková, Hana. "Sulfobutylether-β-cyklodextrin jako chirální selektor pro separace aminokyselin a dipeptidů v HPLC". Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-356361.

Full text
Abstract:
The main aim of this work was to prepare and characterize a new chiral stationary phase (CSP). The CSP was prepared by dynamic coating of sulfobutylether- β-cyclodextrin (SBE-β-CD) on a strong anion-exchange stationary phase (SP). The selectivity and stability of the newly prepared CSP were tested on the sets of chiral and achiral analytes. The next separation system used was composed of C18 SP with the addition of SBE-β-CD as a chiral selector into the mobile phase. The set of chiral analytes contained amino acids phenylalanin, tyrosine, tryptophan, their derivatives and dipeptides glycine-DL
APA, Harvard, Vancouver, ISO, and other styles
9

Šlechtová, Tereza. "Studium kinetiky trypsinového štěpení peptidů a chirálních separací biologicky aktivních látek metodou HPLC." Doctoral thesis, 2016. http://www.nusl.cz/ntk/nusl-353378.

Full text
Abstract:
This dissertation thesis composes of two parts; the first part focus on the characterization of trypsin, enzyme frequently used in proteomic research for the investigation and identification of protein sequences, and its peptide digestion kinetics. The second part is aimed to the enantioseparations of biologically active compounds. First part of this project focus on tryptic digestion of synthetic peptides and the development of HPLC method for the identification of synthetic peptides and their fragments. Using the in-solution digestion and HPLC method, relative kinetic constants were determin
APA, Harvard, Vancouver, ISO, and other styles
10

Repko, Pavel. "Využití chirálních stacionárních fází na bázi teikoplaninu a teikoplanin aglykonu pro enantioseparaci FMOC- derivatizovaných aminokyselin." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-312467.

Full text
Abstract:
In this work, an enantioselective HPLC method with UV and fluorimetric detection was developed and subsequently optimized for chiral separation of four aminoacids (D/L-alanine, D/L-valine, D/L-leucine, D/L-isoleucine) in native and particularly in derivatized form with an emphasis on enantioseparation of D-analogues. Retention and enantioseparation behavior of studied analytes was investigated on three chiral stationary phases based on teicoplanin (Chirobiotic T, Chirobiotic T2) and teicoplanin aglycone (Chirobiotic TAG). At the Chirobiotic T column, enantioseparations of underivatized aminoac
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography