Academic literature on the topic 'Conhydrine'

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Journal articles on the topic "Conhydrine"

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Vicario, Jose, Dolores Badía, Efraim Reyes, Nerea Ruiz, and Luisa Carrillo. "Stereoselective Total Synthesis of (-)-β-Conhydrine and (+)-α-Conhydrine." Synthesis 2011, no. 03 (January 5, 2011): 443–50. http://dx.doi.org/10.1055/s-0030-1258390.

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Chang, Meng-Yang, Yung-Hua Kung, and Shui-Tein Chen. "Synthesis of α-conhydrine." Tetrahedron 62, no. 47 (November 2006): 10843–48. http://dx.doi.org/10.1016/j.tet.2006.09.004.

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Reddipalli, Gowrisankar, Mallam Venkataiah, and Nitin W. Fadnavis. "Stereoselective synthesis of (−)-α-conhydrine." Tetrahedron: Asymmetry 22, no. 18-19 (October 2011): 1778–83. http://dx.doi.org/10.1016/j.tetasy.2011.10.008.

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Kandula, Subba Rao V., and Pradeep Kumar. "Asymmetric synthesis of (−)-α-conhydrine." Tetrahedron: Asymmetry 16, no. 19 (October 2005): 3268–74. http://dx.doi.org/10.1016/j.tetasy.2005.08.045.

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Chavan, Subhash P., Lalit B. Khairnar, Kailash P. Pawar, Prakash N. Chavan, and Sanket A. Kawale. "Enantioselective syntheses of (R)-pipecolic acid, (2R,3R)-3-hydroxypipecolic acid, β-(+)-conhydrine and (−)-swainsonine using an aziridine derived common chiral synthon." RSC Advances 5, no. 62 (2015): 50580–90. http://dx.doi.org/10.1039/c5ra06429e.

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Concise total syntheses of (R)-pipecolic acid, (2R,3R)-3-hydroxypipecolic acid and formal syntheses of β-(+)-conhydrine, (−)-lentiginosine, (−)-swainsonine and -1,2-di-epi-swainsonine have been accomplished starting from a common chiral synthon.
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Penumati, Nageshwar Rao, and Nagaiah Kommu. "Stereoselective Synthesis of (+)-α-Conhydrine from R-(+)-Glyceraldehyde." Organic Chemistry International 2014 (October 20, 2014): 1–7. http://dx.doi.org/10.1155/2014/982716.

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Stereoselective synthesis of (+)-α-Conhydrine was accomplished from protected (R)-(+)-glyceraldehyde, a familiar carbohydrate predecessor. Our synthetic strategy featured the following two key reactions. One is Zn-mediated stereoselective aza-Barbier reaction of imine 6 with allyl bromide to afford chiral homoallylic amine 7, and the other is ring-closing metathesis.
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Itoh, Takashi, Kazuhiro Nagata, and Yosuke Toriizuka. "A Concise Enantioselective Synthesis of (+)-α-Conhydrine." HETEROCYCLES 66, no. 1 (2005): 107. http://dx.doi.org/10.3987/com-05-s(k)44.

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Voituriez, Arnaud, Franck Ferreira, and Fabrice Chemla. "Short and Efficient Asymmetric Synthesis of (−)-α-Conhydrine†." Journal of Organic Chemistry 72, no. 14 (July 2007): 5358–61. http://dx.doi.org/10.1021/jo070760t.

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Enders, Dieter, Bert Nolte, Gerhard Raabe, and Jan Runsink. "Asymmetric synthesis and structural assignment of (−)-α-conhydrine." Tetrahedron: Asymmetry 13, no. 3 (March 2002): 285–91. http://dx.doi.org/10.1016/s0957-4166(02)00066-6.

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Kamal, Ahmed, Saidi Reddy Vangala, N. V. Subba Reddy, and V. Santhosh Reddy. "Stereoselective total synthesis of (+)-β-conhydrine from d-mannitol." Tetrahedron: Asymmetry 20, no. 22 (November 2009): 2589–93. http://dx.doi.org/10.1016/j.tetasy.2009.10.017.

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Dissertations / Theses on the topic "Conhydrine"

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Vidal, Virginie. "Synthèse asymétrique d'analogues d'alcaloïdes pipéridiniques et indolizidiniques à l'aide d'un synthon chiral dérivé d'amino-acide." Paris 11, 1988. http://www.theses.fr/1988PA112316.

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La cyano 2S phényloxazolo 6S pipéridinel (synthon) obtenue en une étape à partir du R(-)phénylglycinol, du glutaraldéhyde et du cyanure de potassium permet des alcoylations régio et stéréosélectives en position C-2 du cycle pipéridinique. Cette thèse décrit l'utilisation de ce composé pour la synthèse asymétrique plusieurs produits en série pipéridinique et indolizidinique. L'alcoylation du synthon l par le dibromopropane a permis d'obtenir après cyclisation de l'azote de la pipéridine sur le brome et élimination de la partie auxiliaire chirale, la première synthèse asymétrique de la (-)-delta-conicéine en trois étapes. L'alcoylation du synthon l par le chloroformiate d'éthyle suivie d'une réduction par !e borohydrure de sodium et hydrogénolyse conduit auR(-)pipécolinol. La réaction de l'anion du synthon sur des aldéhydes a été particulièrement étudiée, elle conduit de manière hautement stéréosélective à des béta aminoalcools. La préparation de la (+)-béta-conhydrine a ainsi été effectuée par alcoylation de. L avec le propionaldéhyde et a ainsi permis de déterminer la configuration absolue de ce produit. En utilisant la même stratégie, une synthèse asymétrique d'une dihydroxyindoliziàine, analogue d'un produit naturel (swainsonine), inhibiteur d'alpha mannosidase a pu être réalisée. Ainsi, l'alcoylation du synthonl par le crotonaldéhyde suivie d'une décyanation par le borohydrure de sodium et époxydarion permet d'obtenir, après cycli­sation de l'azote, sur l'époxyde un analogue de la swainsonine
The 2S cyano 6S oxazolo piperidine (synthon) which is obtained in one step starting from R(-) phenylglycinol, glutaraldehyde and potassium cyanide allows regio and stereoselective alkylations at the C-2 position of the piperidine ring. This thesis describes the usage of this compound in the asymmetric synthesis of severa] products from the piperidinic and indolizidini c series. Alkylation of the synthon I with dibromopropane permitted to obtain, after cyclisation of nitrogen on brome and elimination of the auxiliar chiral chain the first asymmetric synthesis of (-)-delta coniceine in three steps. Reaction of synthon 1 with ethyl chloroformate followed by a reduction with sodium borohydride and hydrogenolysis leads to R(-) pipecolinol. The reaction of the anion of the synthon on aldehydes was studied, in particular, it leads with a high stereoselectivity to beta amino­ alcohols. The preparation of (+)-beta -conhydrine was thus carried out by alkylation of 1 with propionaldehyde and permitted in this way the determination of the absolute configuration of this product. Following this strategy, an asymmetric synthesis of an indolizidine diol, a natural product analog (swainsonine), inhibitor of alpha mannosidase , was achieved. Alkylation of synthon 1 with crotonaldehyde followed by decyanation with sodium borohydride and epoxydation supplies after cyclisation of the nitrogen atom on the epoxide a swainsonine analog
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Pilard, Serge. "Les Omega-azido et aminoépoxydes précurseurs de beta-aminoalcools substitution nucléophile inter et intramoléculaires : synthèse totale des (+/-) alpha et beta conhydrines /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37608912s.

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PILLARD, SERGE. "Les omega -azido et aminoepoxydes precurseurs de beta amino-alcools : substitution nucleophile inter et intramoleculaires, synthese totale des ( +ou- ) alpha et beta conhydrines." Rennes 1, 1987. http://www.theses.fr/1987REN10074.

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Book chapters on the topic "Conhydrine"

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Talapatra, Sunil Kumar, and Bani Talapatra. "Coniine, Conhydrine, and Pseudoconhydrine (The C-Skeleton Derived from a C 8 -Fatty Acid and N from Transamination)." In Chemistry of Plant Natural Products, 733–48. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-45410-3_17.

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Taber, Douglass. "Organic Functional Group Interconversion: (-)- β -Conhydrine (Barua) and (+)-6'-Hydroxyarenarol (Anderson)." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0009.

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V. T. Perchyonok and Kellie L. Tuck of Monash University found (Tetrahedron Lett. 2008, 49, 4777) that a concentrated solution of Bu4NCl and H3PO2 in water effected free radical reductions and cyclizations. Stéphane G. Ouellet of Merck Frosst demonstrated (Tetrahedron Lett. 2008, 49, 6707) that an oxazoline such as 3 could be converted to the alcohol 4 by acylation followed by reduction. Elizabeth R. Burkhardt of BASF developed (Tetrahedron Lett. 2008, 49, 5152) a protocol for scalable reductive amination using an easily metered liquid pyridine-borane complex. Mohammad Movassaghi of MIT devised (Angew. Chem. Int. Ed. 2008, 47, 8909) a strategy for conversion of an allylic carbonate 8 by way of the allylic diazene to the terminal alkene 9. Philippe Compain of the Université d’Orleans uncovered (J. Org. Chem. 2008, 73, 8647) a practical procedure for oxidizing an inexpensive aldose such as 10 to the amide 12, a valuable chiral pool starting material. Karl A. Scheidt of Northwestern University extended (Organic Lett. 2008, 10, 4331) activated MnO2 oxidation to saturated aldehydes such as 13, leading to the ester 15. Tohru Fukuyama of the University of Tokyo showed (Organic Lett. 2008, 10, 2259) that halides such as 16 could be oxidized to the oxime 18 with the reagent 17. The product oximes are readily dehydrated to the corresponding nitriles. Chutima Kuhakarn of Mahidol University devised (Synthesis 2008, 2045) a simple protocol for the oxidation of a primary amine such as 19 to the nitrile 20 . Nasser Iranpoor and Habib Firouzabadi of Shiraz University developed (J. Org. Chem. 2008, 73, 4882) the reagent 22 for Mitsunobu coupling. The stereochemical course of this reaction with simple acyclic secondary alcohols such as 21 was not reported. Salvatore D. Lepore of Florida Atlantic University optimized (Angew. Chem. Int. Ed. 2008, 47, 7511) the quisylate 24 for the displacement with retention to give the azide 25. Hideki Yorimitsu and Koichiro Oshima of Kyoto University optimized (J. Am. Chem. Soc. 2008, 130, 11276) a Co catalyst for the conversion of a secondary halide such as 26 to the terminal alkene 27 . Base-mediated elimination gave primarily the internal alkene.
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Conference papers on the topic "Conhydrine"

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Couture, Axel, Eric Deniau, Marc Lamblin, and Pierre Grandclaudon. "Asymmetric Synthesis of (+)-Coniine,(-)-Coniceine, (+)-b-Conhydrine,(+)-Sedamine and(+)-Allosedamine by a Strategic Combination of RCM with Nucleophilic 1,2-Addition on SAMP-Hydrazones." In The 12th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2008. http://dx.doi.org/10.3390/ecsoc-12-01212.

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