Academic literature on the topic 'Coumarin derivative'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Coumarin derivative.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Coumarin derivative"

1

Min, Su Ji, Heesu Lee, Myoung-Sook Shin, and Jae Wook Lee. "Synthesis and Biological Properties of Pyranocoumarin Derivatives as Potent Anti-Inflammatory Agents." International Journal of Molecular Sciences 24, no. 12 (2023): 10026. http://dx.doi.org/10.3390/ijms241210026.

Full text
Abstract:
This study aimed to synthesize 23 coumarin derivatives and analyze their anti-inflammatory effects on lipopolysaccharide (LPS)-induced inflammation in RAW264.7 macrophages. A cytotoxicity test performed on LPS-induced RAW264.7 macrophages revealed that none of the 23 coumarin derivatives were cytotoxic. Among the 23 coumarin derivatives, coumarin derivative 2 showed the highest anti-inflammatory activity by significantly reducing nitric oxide production in a concentration-dependent manner. Coumarin derivative 2 inhibited the production of proinflammatory cytokines, including tumor necrosis fac
APA, Harvard, Vancouver, ISO, and other styles
2

Al-Harbi, Reem A. K. "Synthesis of New Coumarin Scaffold Bearing 2-Iminochromene Moiety." Acta Chimica Slovenica 70, no. 3 (2023): 380–84. http://dx.doi.org/10.17344/acsi.2023.8016.

Full text
Abstract:
Coumarin is classified as one of interesting therapeutic starting research points to obtain remarkable compounds with high efficacy. So, during this research, new 2-iminochromene derivatives bearing coumarin moiety were synthesized. At first, cyanoacetohydrazone of 3-acetylcoumarin was prepared and used as the starting material. The 2-iminochromene derivatives were synthesized through the ring closure of cyanoacetohydrazone derivative with 4-hydroxysalicylaldehyde, 5-aryldiazosalicylaldehydes, 2-hydroxynaphthaldehyde and 7-hydroxychromone-6-carboxaldehyde derivative. All of the newly synthesiz
APA, Harvard, Vancouver, ISO, and other styles
3

Sanaryh Mohammed Al-awad, Leaqaa Abdalredha raheem, and Ausama Ayob Jaccob. "Synthesis and Pharmacological Evaluation of Novel Coumarin Derivatives." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 865–74. http://dx.doi.org/10.26452/ijrps.v11i1.1908.

Full text
Abstract:
The current work focuses on new architecture, synthesis of coumarin-oxadiazole hybrid derivative products as both these (coumarin ring and oxadiazole) have a wide variety of biological behavior, Compounds containing the nucleus of coumarin (2H-1-benzopyran-2-one) are an interesting class of hetero cycles which hold an important role in the field of natural ingredients and synthetic organic chemistry. It has been exciting medicinal chemists to study native coumarins or synthetic analogs for their application for decades. And they can be further modified to synthesize more effective and potent d
APA, Harvard, Vancouver, ISO, and other styles
4

Kumari, Sumita, Amit Sharma, and Sonia Yadav. "Pharmacological Potential of Coumarin-Based Derivatives: (A Comprehensive Brief Review)." Oriental Journal Of Chemistry 39, no. 3 (2023): 568–76. http://dx.doi.org/10.13005/ojc/390304.

Full text
Abstract:
By combining of benzene nucleus and pyrone ring a class of heterocyclic compounds known as benzopyrone is generated. As a basic parent scaffold 1,2- benzopyrone ring system contains by coumarins. These compounds can be divided into two groups: 1. Benzo-α-pyrone 2. Benzo-γ-pyrone. Data on different coumarin derivatives are gathered in this review article as these compounds have a wide spectrum of pharmacological actions and can be further modified to make more potent and effective medications. Derivatives of coumarin play a significant role in industries and sectors of medicine. This can be lin
APA, Harvard, Vancouver, ISO, and other styles
5

Hwang, Sumi. "Antibacterial Activity for Synthesized Coumarin Derivatives and a Coumarin Component of Lime Peel (Citrus aurantifolia)." Bioengineering 11, no. 8 (2024): 752. http://dx.doi.org/10.3390/bioengineering11080752.

Full text
Abstract:
In this study, we investigated the antibacterial activity of the coumarin component isolated from lime peel and coumarin derivatives synthesized using various techniques against eight types of food-poisoning bacteria. The minimum inhibitory concentration (MIC) for the 3b [5,7-dihydroxy-4-trifluoromethylcoumarin] derivative was measured as 1.5 mM in Bacillus cereus, Micrococcus luteus, Listeria monocytogenes, and Staphylococcus aureus subsp. aureus; that for the 3c [7-hydroxy-4-trifluoromethylcoumarin] derivative was 1.7 mM in Enterococcus facium; and that for the 3n [dicoumarol] derivative was
APA, Harvard, Vancouver, ISO, and other styles
6

Kashirin, Anton O., Irina B. Krylova, Elena N. Selina, et al. "Antihypoxic effect of new synthetic derivatives of 7-alkoxycoumarin and 4-aminocoumarin in acute hypobaric hypoxia in rats." Reviews on Clinical Pharmacology and Drug Therapy 19, no. 4 (2021): 413–20. http://dx.doi.org/10.17816/rcf194413-420.

Full text
Abstract:
BACKGROUND: Coumarins are naturally occurring molecules with a wide range of pharmacological activities. Their use is limited by difficulties in isolation from plant material, toxicity, and low solubility. The chemical structure of these compounds makes coumarins promising for the synthesis of a large number of derivatives that may have biological activity and be of interest as potential drugs. We had synthesized coumarin derivatives, two of which IEM-2266 (7-alkoxycoumarin derivative) and IEM-2267 (4-aminocoumarin derivative) have shown antihypoxic effect in mice in models of hypoxic hypoxia
APA, Harvard, Vancouver, ISO, and other styles
7

Gümüş, Hacer. "Evaluation of the Antioxidant Properties of Coumarin Derivatives Using Spectroscopic Methods." Clinical Cardiology and Cardiovascular Interventions 7, no. 10 (2024): 01–06. https://doi.org/10.31579/2641-0419/399.

Full text
Abstract:
Coumarin derivatives are perceived as part of defense mechanisms in plants due to their commonly observed antimicrobial, antioxidant, antitumor, anti-inflammatory, and other biological activities. Investigating the molecular structure of coumarin derivatives using computational programs like Gaussian is an effective method for understanding the biological, chemical, and physical properties of these compounds. Therefore, in this study, the molecular structure parameters and spectroscopic (IR, NMR) properties of our coumarin derivative compound were theoretically examined using the DFT method wi
APA, Harvard, Vancouver, ISO, and other styles
8

U., C. Mashelkar, and A. Audi A. "Synthesis of some novel 4-substituted coumarins having antibacterial activity (Part-I)." Journal of Indian Chemical Society Vol. 82, Mar 2005 (2005): 254–57. https://doi.org/10.5281/zenodo.5827011.

Full text
Abstract:
Organic Research Laboratory. SS &amp; LS Patkar College, Goregaon (W). Mumbai-400 062, India E-mail: ajayaaudi@rediffmail.com&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Fax : 91-22-28744755 <em>Manuscript received 13 February 2004, revised 1 September 2004, accepted 24 November 2004</em> Methyl coumarin-4-methyl acetate on bromination in dioxane or dichloroethane as solvent resulted in sidechain bromination giving a-bromo derivative. The same r
APA, Harvard, Vancouver, ISO, and other styles
9

Adeleke, Richard, Idayat Sulaıman, Sunday Wilson Balogun, Wahab Osunniran, Sikiru Ahmed, and Olusola James. "Computational Studies of Suitability of Triarylmethane-Coumarins as Sensitizer for Dye-Sensitized Solar Cells." Turkish Computational and Theoretical Chemistry 8, no. 3 (2024): 66–73. http://dx.doi.org/10.33435/tcandtc.1349520.

Full text
Abstract:
Triarylmethanes are low cost synthetic dyes with intense absorption in the visible spectrum. This make it attractive to explore their suitability as sensitizer for dye sensitized solar cell. Using malachite green as a lead dye, we made intuitive structural modifications: incorporation of coumarin-3-carboxylic acid as acceptor/anchor, and substituting one or the two N, N-diethylaniline donors with N-propyl-1,6dimethyllutidine(s). The three resulting triarylmethane-coumarin structures were subjected to DFT calculations to investigate their suitability as sensitizers for DSSC applications. The ca
APA, Harvard, Vancouver, ISO, and other styles
10

Szafraniec, Anna, and Waldemar Iwanek. "Intramolecular Hydrogen Bond Driven Conformational Selectivity of Coumarin Derivatives of Resorcin[4]arene." International Journal of Molecular Sciences 21, no. 17 (2020): 6160. http://dx.doi.org/10.3390/ijms21176160.

Full text
Abstract:
In this study, the synthesis and structure of 4-aminocoumarin derivatives of resorcin[4]arene were investigated. Spectroscopic analysis and quantum mechanical calculations showed that this molecule undertakes a crown-in conformation in chloroform. The conformations of the aminocoumarin derivative of resorcin[4]arene were compared with a hydroxycoumarin derivative of resorcin[4]arene, and the effect of the substituent on the conformational selectivity of the coumarin derivatives of resorcin[4]arene was demonstrated. Both UV-VIS and fluorescence spectroscopy for the coumarin derivative of resorc
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Coumarin derivative"

1

Sabbagh, Liezel Veronica. "Chemical studies of chromone derivatives." Thesis, Rhodes University, 2001. http://hdl.handle.net/10962/d1006899.

Full text
Abstract:
This study has focussed on several aspects of chromone chemistry, viz., (i) the influence of remote substituents on the basicity of 2-(N,N-dimethylamino)chromones, (ii) MoritaBaylis-Hillman reactions of substituted chromone-3-carbaldehydes and (iii) an investigation into the application of chromone chemistry in the total synthesis of the marine natural product, Rietone A. Selected 2-(N,N-dimethylamino )chromones were prepared using two different methods; firstly, via cyclisation of salicylate-derived N,N-dimethyl-3;.(2-hydroxyphenyl)-3- oxopropanamide precursors and, secondly, via 2-hydroxyace
APA, Harvard, Vancouver, ISO, and other styles
2

Musa, Musiliyu Ayodele. "Applications of the Baylis-Hillman reaction in the synthesis of coumarin derivatives." Thesis, Rhodes University, 2003. http://eprints.ru.ac.za/2319/1/MUSA-PhD-TR03-74.pdf.

Full text
Abstract:
The reaction of specially prepared salicylaldehyde benzyl ethers with the activated alkenes, methyl acrylate or acrylonitrile, in the presence of the catalyst, DABCO, has afforded Baylis-Hillman products, which have been subjected to conjugate addition with either piperidine or benzylamine. Hydrogenolysis of these conjugate addition products in the presence of a palladium-on-carbon catalyst has been shown to afford the corresponding 3-substituted coumarins, while treatment of O-benzylated Baylis-Hillman adducts with HCl or HI afforded the corresponding 3-(halomethyl)coumarins directly, in up
APA, Harvard, Vancouver, ISO, and other styles
3

Repsold, Benjamin Petrus. "Inhibition of monoamine oxidase B by substituted coumarin derivatives / Bennie Repsold." Thesis, North-West University, 2008. http://hdl.handle.net/10394/4177.

Full text
Abstract:
Interest in the selective inhibition of monoamine oxidase B (MAO-B) has increased in the last years due to their therapeutic potential in age related neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Reversibly inhibiting MAO-B reduces the oxidative deamination of dopamine, increases dopamine levels and, consequently, reduces the production of reactive oxygen species (ROS) which may be the therapeutic intervention that positively affect the tempo and progression of neurodegenerative diseases. Coumarin analogues exhibit a broad spectrum of pharmacological activity,
APA, Harvard, Vancouver, ISO, and other styles
4

Robinson, Ross Stuart. "Baylis-Hillman derived benzopyrans and related systems : a synthetic and mechanistic study." Thesis, Rhodes University, 1998. http://hdl.handle.net/10962/d1007193.

Full text
Abstract:
The Baylis-Hillman reaction between substituted salicylaldehydes and various acrylate species has been shown to afford complex reaction mixtures, careful chromatography of which has led to the isolation of an extensive range of novel compounds. One- and two-dimensional NMR spectroscopic, mass spectrometric and X-ray crystallographic analysis of these compounds have permitted identification of no less than eight general classes of chromene and coumarin derivatives. The formation of the various product types is attributed to cascades of successive reactions stemming, in each case, from a Baylis-
APA, Harvard, Vancouver, ISO, and other styles
5

Ramaite, Ipfani David Isaiah. "Synthetic and physical organic studies of chromone derivatives." Thesis, Rhodes University, 1997. http://hdl.handle.net/10962/d1005045.

Full text
Abstract:
A range of chromone-2-carboxylic acids has been prepared by condensing suitably substituted 2-hydroxyacetophenones with diethyl oxalate. pK₂ Studies of these acids revealed that 6- or 7-methoxy substituents decreased acidity while the 6-nitro group enhanced acidity; the strongest acid was the 3-chloro derivative, the increase in acidity being attributed to steric inhibition of acid-weakening delocalisation between the carboxyl group and the chromone system. Various chromone-2-carboxamides, derived from acid chloride precursors, were converted to polysubstituted acrylamides by nucleophilic ring
APA, Harvard, Vancouver, ISO, and other styles
6

Rodriguez, Dominguez Juan Carlos. "Nouvelles synthèses de dérivés hetérocycliques pour applications biologiques : (Céphalosporines, Coumarines et Indoles) = New synthesis of heterocyclic derivatives for biological applications (Cephalosporins, Coumarins and Indoles)." Metz, 2006. http://docnum.univ-lorraine.fr/public/UPV-M/Theses/2006/Rodriguez_Dominguez_Juan_Carlos_SMZ0618.pdf.

Full text
Abstract:
Les céphalosporines de synthèse, les dérivés de coumarines et indoles sont des composés très intéressant dans le domaine de la biochimie. Les premières sont utilisées habituellement dans le système de santé mondiale contre les infections bactériennes ; les secondes et les dernières, sont présentes dans les sciences de la nature et de la vie avec des larges gammes d'activités et des usages biologiques. Due à leurs importantes applications, il apparait nécessaire d'avoir des méthodes efficaces pour synthétiser ces produits. Des temps de réactions plus courts, de bons rendements, un travail fait
APA, Harvard, Vancouver, ISO, and other styles
7

Rodriguez, Dominguez Juan Carlos Kirsch Gilbert Prieto Sylvia. "Nouvelles synthèses de dérivés hetérocycliques pour applications biologiques (Céphalosporines, Coumarines et Indoles) = New synthesis of heterocyclic derivatives for biological applications (Cephalosporins, Coumarins and Indoles) /." [S.l.] : [s.n.], 2006. ftp://ftp.scd.univ-metz.fr/pub/Theses/2006/Rodriguez%20Dominguez.Juan%20Carlos.SMZ0618.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Rose, Nathan Rolf. "Synthesis of novel coumarin derivatives as potential inhibitors of HIV-1 protease." Thesis, Rhodes University, 2007. http://hdl.handle.net/10962/d1007220.

Full text
Abstract:
This research has focused on the development of novel coumann derivatives containing peptide-like side chains as potential HIV-1 protease inhibitors. The reaction of various salicylaldehyde derivatives with tert-butyl acrylate In the presence of 1,4- diazabicyclo[2.2.2]octane (DABCO) has afforded a series of Baylis-Hillman adducts in moderate yield. Cyclisation of the adducts in the presence of HCI afforded the corresponding 3-(chloromethyl)coumarin derivatives, which have been reacted with various amine hydrochlorides in the presence of Proton Sponge® to afford a series of novel 3- (aminometh
APA, Harvard, Vancouver, ISO, and other styles
9

Ramaite, Ipfani David Isaiah. "Chemical and spectroscopic studies of chromone derivatives." Thesis, Rhodes University, 1993. http://hdl.handle.net/10962/d1006888.

Full text
Abstract:
A number of biologically active chromones occur in plants (eg. Khellin) and research in this field has eventually led to the discovery of chromoglycic acid, which is widely used as a sodium salt in asthma therapy. Since biological activity may be related to acidity, a range of chromone-2-carboxylic acids have been prepared via Claisen acylation of substituted o- hydroxyacetophenones and their acid dissociation constants determined potentiometrically to explore substituent effects. From this study it has been found that introduction of certain groups does have a marked effect on acidity. A vari
APA, Harvard, Vancouver, ISO, and other styles
10

Concannon, Shauna. "A study of the isolation, synthesis, structural elucidation and biological properties of coumarin derivatives." Thesis, University of Ulster, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274067.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Coumarin derivative"

1

Gábor, M. The pharmacology of benzopyrone derivatives and related compounds. Akadémiai Kiadó, 1986.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

Concannon, Shauna. A study of the isolation, synthesis, structural elucidation and biological properties of coumarin derivatives. The author], 2001.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

Vekariya, Mitesh B., Jayeshkumar S. Babariya, and Krushnakumar J. Jilariya. Synthesis and Characterization of Some Novel Coumarin Derivative and Study of Crystalography. Lulu Press, Inc., 2019.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Coumarin and Its Derivatives. MDPI, 2021. http://dx.doi.org/10.3390/books978-3-0365-2774-1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Matos, Maria João. Coumarin and Its Derivatives. Mdpi AG, 2021.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

Applications of Coumarin Derivatives [Working Title]. IntechOpen, 2019. http://dx.doi.org/10.5772/intechopen.80202.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Penta, Santhosh. Advances in Structure and Activity Relationship of Coumarin Derivatives. Elsevier Science & Technology Books, 2015.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Advances in Structure and Activity Relationship of Coumarin Derivatives. Elsevier, 2016. http://dx.doi.org/10.1016/c2015-0-00450-6.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Penta, Santhosh. Advances in Structure and Activity Relationship of Coumarin Derivatives. Elsevier Science & Technology Books, 2015.

Find full text
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Coumarin derivative"

1

Avdović, Edina, Dušan Dimić, and Dejan Milenković. "Investigation of Coumarin Derivative 3-(1-o-toluidinoethylidene)-chromane-2,4-dione: IR Spectroscopic Characterization, NBO, and AIM Analysis and Molecular Docking Studies." In Learning and Analytics in Intelligent Systems. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-43658-2_12.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Pozzan, Alfonso, Manlio Palumbo, Francesco Dall’Acqua, and Massimo Mabilia. "Photoreactivity of coumarin derivatives: Pattern recognition and QSAR Studies." In Trends in QSAR and Molecular Modelling 92. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1472-1_65.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Rani, Pooja. "Fluorescence Characteristics of Coumarin Derivatives with Divalent Metal Ions." In Computational and Experimental Methods in Mechanical Engineering. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2857-3_26.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Sharma, Rajesh Kumar, and Diksha Katiyar. "Recent Advances in the Development of Coumarin Derivatives as Antifungal Agents." In Recent Trends in Human and Animal Mycology. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9435-5_10.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

More, Kerba S., and Sheshanath V. Bhosale. "Synthesis of π-conjugated coumarins and their derivatives for supramolecular applications." In Nanoscience. Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839163791-00053.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Choi, Y. H., J. Kim, M. J. Noh, E. S. Choi, and K. P. Yoo. "Effect of Functional Groups on the Solubilities of Coumarin Derivatives in Supercritical Carbon Dioxide." In ACS Symposium Series. American Chemical Society, 1997. http://dx.doi.org/10.1021/bk-1997-0670.ch009.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Xue, Yong, and Qingfang He. "Synthetic Biology Approaches to the Sustainable Production of p-Coumaric Acid and Its Derivatives in Cyanobacteria." In Synthetic Biology of Cyanobacteria. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-0854-3_11.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Gambacorta, Nicola, Marco Catto, Leonardo Pisani, Angelo Carotti, and Orazio Nicolotti. "Informed Use of 3D-QSAR for the Rational Design of Coumarin Derivatives as Potent and Selective MAO B Inhibitors." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2643-6_15.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Netter, K. J., B. Hahnemann, S. A. Mangoura, et al. "Selective Inducers of the Coh-Locus Enhance the Metabolisms of Coumarin- and of Quinoline-Derivatives but Not That of Naphthalenes." In Advances in Experimental Medicine and Biology. Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4684-5877-0_46.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Sharma, Deepika, Vasudevan Dhayalan, Chitrarasu Manikandan, and Rambabu Dandela. "Recent Methods for Synthesis of Coumarin Derivatives and Their New Applications." In Strategies Towards the Synthesis of Heterocycles and Their Applications [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108563.

Full text
Abstract:
Coumarin (2H-1-benzopyran-2-one) and its heterocyclic derivatives are widely used as lactone scaffolds used by innovative methods for the preparation of heterocyclic molecules. Nowadays, significant biological activities, as well as properties of unique nature coumarin derivatives, have played an important role in the development of novel drugs. This chapter entitles numerous methods of one-pot construction of coumarin derivatives, together with well-known name reactions and other type reactions as well, in the presence of various metal-based homogenous and heterogeneous catalyst system. Couma
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Coumarin derivative"

1

Renuka, C. G. "Solvatochromism and electronic structure of coumarin derivative." In 3RD INTERNATIONAL CONFERENCE ON CONDENSED MATTER AND APPLIED PHYSICS (ICC-2019). AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0001777.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Dimić, Dušan, Dejan Milenković, Edina Avdović, Goran Kaluđerović, and Jasmina Dimitrić Marković. "MOLECULAR DOCKING AND MOLECULAR DYNAMICS STUDIES OF THE INTERACTION BETWEEN COUMARIN-NEUROTRANSMITTER DERIVATIVES AND CARBONIC ANHYDRASE IX." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.056d.

Full text
Abstract:
Novel biologically active compounds can be obtained by the structural modification of coumarins. In this contribution, five new derivatives of 4-hydroxycoumarin with tyramine, octopamine, norepinephrine, 3-methoxytyramine, and dopamine were obtained. Their structures were optimized based on the previously obtained crystal structure of the 4-hydroxycoumarin-dopamine derivative. The special emphasis was put on the effect of various substituents on the structure of obtained compounds and intramolecular interactions governing the stability. To investigate their possible antitumor activity, molecul
APA, Harvard, Vancouver, ISO, and other styles
3

Zhao, Yuxia, Ying Gu, Shaona Zhou, and Zhiyuan Sun. "A quaternary ammonium modified coumarin derivative for antimicrobial photodynamic therapy." In Photonic Diagnosis and Treatment of Infections and Inflammatory Diseases, edited by Tianhong Dai. SPIE, 2018. http://dx.doi.org/10.1117/12.2287086.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Avdović, Edina, Sandra Jovičić Milić, Dušica Simijonović, Danijela Stojković, Dejan Milenković, and Zoran Marković. "SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND BSA INTERACTIONS OF 3-(1-((4-HYDROXY PENTYLAMINO)ETHYLIDENE)CHROMAN-2,4-DIONE." In 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry. Society of Physical Chemists of Serbia, 2024. https://doi.org/10.46793/phys.chem24i.053a.

Full text
Abstract:
In this study, we synthesized a novel coumarin derivative, specifically 3-(1-((4-hydroxy pentylamino)ethylidene)cromane-2,4-dione by the reaction of 3-acetyl-4-hydroxycoumarin and 5- aminopentanol in methanol. The compound was obtained after 2 hours of reflux. The synthesized coumarin derivative was obtained in very good yield (80%) and characterized using elemental microanalysis, Uv-Vis, IR and NMR spectroscopy. Furthermore, the interaction of investigated compound with bovine serum albumin (BSA) was studied using fluorescence spectroscopy and the Stern-Volmer constant (Ksv), quenching rate c
APA, Harvard, Vancouver, ISO, and other styles
5

Patil, Omnath, P. K. Ingalagondi, G. B. Mathapati, and S. M. Hanagodimath. "Analysis of fluorescence quenching of coumarin derivative dye using Stern-Volmer plots." In ADVANCES IN BASIC SCIENCE (ICABS 2019). AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5122630.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Zhang, Peng, Tianzhi Yu, Yuling Zhao, and Duowang Fan. "Crystal Structure, UV-vis Absorption and Fluorescent Properties of a Novel Coumarin Derivative." In 2007 International Nano-Optoelectronics Workshop. IEEE, 2007. http://dx.doi.org/10.1109/inow.2007.4303004.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Pramod, A. G., Y. F. Nadaf, C. G. Renuka, and M. Sucheta. "Deep blue light emission of (4,3-Oxo‒HCMM) coumarin derivative for organic LED display application." In PROF. DINESH VARSHNEY MEMORIAL NATIONAL CONFERENCE ON PHYSICS AND CHEMISTRY OF MATERIALS: NCPCM 2018. Author(s), 2019. http://dx.doi.org/10.1063/1.5098659.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Seidel, Claus A. M. "Nucleic acid base specific quenching of coumarin-120-derivative in nucleotid-conjugates-photoinduced electron transfer." In Optics, Electro-Optics, and Laser Applications in Science and Engineering, edited by Robert R. Birge and Laurence A. Nafie. SPIE, 1991. http://dx.doi.org/10.1117/12.44215.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Kurjan, Jakub, Rastislav Jendželovský, Zuzana Jendželovská, et al. "A novel silver complex with 4-hydroxycoumarin derivative: Synthesis, structure, and biological activity." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.447k.

Full text
Abstract:
In this contribution, a novel coumarin-derivative ligand, and its silver(I) complex are reported. Ligand 3-(1-(2-pyridylamino)ethylidene)-2H-chromene-2,4-dione (HL) was prepared by reaction of 3-acetyl-4-hydroxycoumarin with 2-picolyl amine. Further, complex [Ag(HL)2]NO3 was prepared and both compounds were characterized by physico-chemical methods such as IR and NMR spectroscopy, elemental analysis, and structure of the ligand and the complex was confirmed by X-ray analysis. The stability of both compounds was measured by NMR spectroscopy. MTT assay and cell proliferation assay on human lung
APA, Harvard, Vancouver, ISO, and other styles
10

Lin, Pi-Han, Tzu-Ming Jao, Yu-Lin Hung, Hsing-Pang Hsieh, Ya-Chien Yang, and Sui-Yuan Chang. "Abstract 1754: BPR2P001S0, a Coumarin derivative, induced cell cycle arrest in A549 through inhibiting PDPK1 activity." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-1754.

Full text
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!