Relevant bibliographies by topics / Cyclohexylamine derivatives

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Academic literature on the topic 'Cyclohexylamine derivatives'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Cyclohexylamine derivatives"

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Chepur, S. V., S. E. Galan, M. S. Vakhviayanen, R. N. Khromov, and A. N. Semenov. "EXPERIMENTAL EVALUATION OF TOXICOMETRIC INDICATORS AND ANALGESIC ACTIVITY OF KAPPA-OPIOID RECEPTOR AGONISTS." Toxicological Review, no. 4 (August 1, 2020): 27–33. http://dx.doi.org/10.36946/0869-7922-2020-4-27-33.

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Data on the biological activity of kappa-opioid receptor agonists - derivatives of three groups of compounds: 1,2-cyclohexylamine, 1,2,3,4-piperidine, 1,2,4-piperazine are presented. On the examples of 1,2-cyclohexylamine and 1,2,4-piperazine derivatives, it has been shown that a decrease in the length of the carbon chain in the phenylalkyl substituent at the nitrogen atom is accompanied by a decrease in the analgesic activity and toxicity of compounds. The replacement of chlorine atoms in the 3 and 4 positions of the phenyl ring with fluorine atoms, which are more electronegative, leads to an
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2

Glushkov, V. A., O. S. P’yankova, L. V. Anikina, et al. "Synthesis and biological activity of cyclohexylamine derivatives." Pharmaceutical Chemistry Journal 40, no. 6 (2006): 298–302. http://dx.doi.org/10.1007/s11094-006-0114-7.

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Llona-Minguez, Sabin, and Simon P. Mackay. "Stereoselective synthesis of carbocyclic analogues of the nucleoside Q precursor (PreQ0)." Beilstein Journal of Organic Chemistry 10 (June 11, 2014): 1333–38. http://dx.doi.org/10.3762/bjoc.10.135.

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A convergent and stereoselective synthesis of chiral cyclopentyl- and cyclohexylamine derivatives of nucleoside Q precursor (PreQ0) has been accomplished. This synthetic route allows for an efficient preparation of 4-substituted analogues with interesting three-dimensional character, including chiral cyclopentane-1,2-diol and -1,2,3-triol derivatives. This unusual substitution pattern provides a useful starting point for the discovery of novel bioactive molecules.
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4

Suzuki, Aya, Hiroyuki Miyamura, and Shū Kobayashi. "Highly Selective Reductive Cross-Amination between Aniline or Nitroarene Derivatives and Alkylamines Catalyzed by Polysilane-Immobilized Rh/Pt Bimetallic Nanoparticles." Synlett 30, no. 04 (2019): 387–92. http://dx.doi.org/10.1055/s-0037-1611341.

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Reductive cross-amination between imine intermediates generated through partial hydrogenation of aniline or nitroarene derivatives and alkylamines is an ideal method for obtaining N-alkylated cyclohexylamine derivatives; however, no such transformations have hitherto been established. Here, we report a highly selective reductive cross-amination using aniline derivatives and alkylamines catalyzed by heterogeneous Rh/Pt bimetallic nanoparticles under mild conditions. The catalyst was recovered and reused for five runs, keeping high activity. In this reaction, imine intermediates generated during
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5

Georgieva, Maya, Javor Mitkov, Lily Peikova, Plamen Peikov, and Alexander Zlatkov. "SYNTHESIS EVALUATION AND QUANTUM MECHANICAL CHARACTERIZATION OF CYCLOHEXYLAMINE CONTAINING DERIVATIVES OF METHYLXANTHINE." CBU International Conference Proceedings 4 (September 26, 2016): 879–87. http://dx.doi.org/10.12955/cbup.v4.868.

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The synthesis of methylxanthine derivatives could provide a sound approach to developing new analogues with similar or novel pharmacological profiles. The synthesis of six new compounds: two derivatives of 8-substituted-1,3,7-trimethylxanthine and four derivatives of 1-propyl-3,7-dimethylxanthine containing a cyclohexyl fragment, are presented. The structures were confirmed by elemental analyses using Furrier Transform Infrared Spectroscopy (FTIR) and Nuclear Magnetic Resonance (NMR) spectral data. The chemical reactivity of the new molecules was assessed, based on computed values for their el
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Zificsak, Craig A., Jay P. Theroff, Lisa D. Aimone, et al. "Methanesulfonamido-cyclohexylamine derivatives of 2,4-diaminopyrimidine as potent ALK inhibitors." Bioorganic & Medicinal Chemistry Letters 21, no. 13 (2011): 3877–80. http://dx.doi.org/10.1016/j.bmcl.2011.05.040.

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Castañeta, Grover, Rodrigo Villagomez, Efrain Salamanca, et al. "Microwave-Assisted Semisynthesis and Leishmanicidal Activity of Some Phenolic Constituents from Lichens." Separations 10, no. 10 (2023): 524. http://dx.doi.org/10.3390/separations10100524.

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Leishmaniasis is considered one of the most untreated tropical diseases in the world. In this study, we investigated the in vitro leishmanicidal activity and cytotoxicity of various isolated lichen substances, including atranorin (1), usnic acid (2), gyrophoric acid (3), salazinic acid (4), galbinic acid (5), and parietin (6), and some semi-synthetic imine derivatives of usnic acid (7, 8, 9) and atranorin (10, 11, 12, 13). Imine condensation reactions with hydrazine and several amines were assisted by microwave heating, an efficient and eco-friendly energy source. The most interesting result w
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Čeřovský, Václav, Taťána Saks, and Karel Jošt. "Papain-catalyzed synthesis of 2-naphthylamides of N-acylamino acids and dipeptides." Collection of Czechoslovak Chemical Communications 52, no. 9 (1987): 2309–16. http://dx.doi.org/10.1135/cccc19872309.

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2-Naphthylamides of several N-acylamino acids were prepared by papain-catalyzed condensation reaction in acidic medium. Under the same conditions, papain catalyzed the synthesis of peptide bond between benzyloxycarbonylglycine and phenylalanine 2-naphthylamide and between benzyloxycarbonylserine and tyrosine 2-naphthylamide. Phenylalanine 2-naphthylamide was also acylated with benzyloxycarbonyl glycine methyl ester in an alkaline medium. For comparison, papain-catalyzed condensations of benzyloxycarbonyl-S-benzylcysteine or benzyloxycarbonylalanine with aniline and its derivatives, benzylamine
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MOHAMED, ABBAS METWALLY, and M. KHALIL ABDEL-GALIL. "Synthesis of Azabicyclo[3.3.1 ]nonanes and Dibenzo[b,d]pyrans from 3-Aryl-2,4-dicarboethoxy-5-hydroxy-5-methyl-cyclohexanones as Potential Antimicrobial Agents." Journal of Indian Chemical Society Vol. 65, Nov 1988 (1988): 766–67. https://doi.org/10.5281/zenodo.6087498.

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Department of Chemistry, Faculty of Science, University of Mansoura, Mansoura, Egypt <em>Manuscript received 19 January&nbsp;1988, revised 27&nbsp;&nbsp;May&nbsp;1988, accepted&nbsp;2 August&nbsp;1988</em> Double Mannich reaction or 1a, c with formalin and benzylamine or cyclohexylamine gave 3-azabicyclo [3 3.1]&nbsp;nonane derivatives (2a, b), while&nbsp; the Pechmann reaction of 1a, c&nbsp;gave the dlbenzopyrans (4, 5). The structures of the compounds have been confirmed by ir, pmr and mass spectral data.
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Štetinová, Jarmila, Adolf Jurášek, Jaroslav Kováč, Miloslava Dandárová, and Oľga Rajniaková. "Synthesis and properties of 4-alkylaminomethyl and 4-alkoxymethyl derivatives of 5-methyl-2-furancarboxylic acid." Collection of Czechoslovak Chemical Communications 51, no. 10 (1986): 2186–92. http://dx.doi.org/10.1135/cccc19862186.

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New β-substituted amines and ethers of the furan series (II-V) were prepared by reaction of methyl 4-bromomethyl-5-methyl-2-furancarboxylate (I) with nucleophiles such as pyrrolidine, piperidine, morpholine, N-phenylpiperazine, cyclohexylamine, 2-methylcyclohexylamine, N-ethylaniline, p-toluidine, ethanol, butanol and salicylaldehyde. The structure of the products was confirmed by their analytical and spectral data. Kovats indices I for the products were determined using gas-liquid chromatography.
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Conference papers on the topic "Cyclohexylamine derivatives"

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Kouznetsov, D. L., O. Yu Podkopaeva, Yu V. Chizhov, G. P. Antroshenko, S. M. Shevchenko, and A. I. Altsybeeva. "Relationship between the Structure and Activity of Volatile Corrosion Inhibitors Derived from Cyclic Amines." In CORROSION 2001. NACE International, 2001. https://doi.org/10.5006/c2001-01192.

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Abstract Products of the condensation reaction between morpholine or cyclohexylamine and benzaldehydes have been used extensively as volatile inhibitors of atmospheric corrosion, as well as components of lubricant compositions, biocides and preservatives in automotive cooling liquids and fuels. In this study, we examined the relationship between the electronic structure and inhibition performance of the compounds in an atmospheric corrosion test. The condensation products have significantly lower vapor pressure than parent amines, resulting in longer residence times of inhibitor species at a m
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