Academic literature on the topic 'Cynaropicrin'

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Journal articles on the topic "Cynaropicrin"

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da Silva, Cristiane França, Denise da Gama Jaen Batista, Julianna Siciliano De Araújo, et al. "Activities of Psilostachyin A and Cynaropicrin against Trypanosoma cruziIn VitroandIn Vivo." Antimicrobial Agents and Chemotherapy 57, no. 11 (2013): 5307–14. http://dx.doi.org/10.1128/aac.00595-13.

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ABSTRACTIn vitroandin vivoactivities againstTrypanosoma cruziwere evaluated for two sesquiterpene lactones: psilostachyin A and cynaropicrin. Cynaropicrin had previously been shown to potently inhibit African trypanosomesin vivo, and psilostachyin A had been reported to showin vivoeffects againstT. cruzi, albeit in another test design.In vitrodata showed that cynaropicrin was more effective than psilostachyin A. Ultrastructural alterations induced by cynaropicrin included shedding events, detachment of large portions of the plasma membrane, and vesicular bodies and large vacuoles containing me
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Lepore, Saverio M., Valentina Maggisano, Giovanni E. Lombardo, et al. "Antiproliferative Effects of Cynaropicrin on Anaplastic Thyroid Cancer Cells." Endocrine, Metabolic & Immune Disorders - Drug Targets 19, no. 1 (2019): 59–66. http://dx.doi.org/10.2174/1871530318666180928153241.

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Background: The sesquiterpene lactone cynaropicrin, a major constituent of the artichoke leaves extracts, has shown several biologic activities in many preclinical experimental models, including anti-proliferative effects. Objective: Herein we evaluated the effects of cynaropicrin on the growth of three human anaplastic thyroid carcinoma cell lines, investigating the molecular mechanism underlying its action. Method: MTT assay was used to evaluate the viability of CAL-62, 8505C and SW1736 cells, and flow cytometry to analyse cell cycle distribution. Western blot was performed to detect the lev
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Nakamura, Tenma, Dinda B. Pitna, Kogaku Kimura, et al. "Total synthesis of cynaropicrin." Organic & Biomolecular Chemistry 19, no. 27 (2021): 6038–44. http://dx.doi.org/10.1039/d1ob00657f.

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The first total synthesis of the sesquiterpene lactone cynaropicrin, isolated from artichoke, was achieved starting from (S)-α-pinene. The synthesis involved a stereoselective Favorskii rearrangement and a diastereoselective Barbier reaction.
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Nowak, Gerard, Miroslav Holub, and Miloš Buděšínský. "Sesquiterpene lactones. XXXIV. Guaianolides in the genus Leuzea DC." Acta Societatis Botanicorum Poloniae 57, no. 1 (2014): 157–63. http://dx.doi.org/10.5586/asbp.1988.015.

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Guaianolides were found in three species of the genus <em>Leuzea</em> DC. Chlorojanerin, cynaropicrin and janerin were isolated from <em>L. rhapontica</em> subg. <em>helenifolia</em> (Gren, Gordon) Holub and <em>L. rhaponticoides</em> Graells. From <em>L. carthamoides</em> (Willd.) DC., chlorojanerin, cynaropicrin, janerin, cebellin E and repdiolide were obtained.
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Adekenova, A. S. "Reference Standards Based on the Grosheimin and Cynaropicrin." Eurasian Chemico-Technological Journal 18, no. 1 (2016): 73. http://dx.doi.org/10.18321/ectj399.

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The aim of this work is the development of effective method for producing the reference standards of Grosheimin and Cynaropicrin for quality control of domestic herbal medicines, as well as project development concerning normative documents on reference standards of Grosheimin and Cynaropicrin, an introduction of reference standards to the Pharmacopoeia of Kazakhstan. This article discusses the method of allocation and purification of reference standards of Grosheimin and Cynaropicrin which are sesquiterpene lactones of guaiane type were obtained from the ethyl acetate extract of <em>Cha
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Sato, Takuya, Shihori Hara, Makiko Sato, Keita Ogawa, Michael Adams, and Toyonobu Usuki. "Synthesis of cynaropicrin- d 4." Bioorganic & Medicinal Chemistry Letters 25, no. 23 (2015): 5504–7. http://dx.doi.org/10.1016/j.bmcl.2015.10.065.

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Nowak, Gerard, Bohdan Drożdż, Miroslav Holub, and Agnieszka Łagodzińska. "Sesquiterpene lactones. XXXIII. Guaianolides in the subgenus Psephellus (Cass.) Schmalh., genus Centaurea L." Acta Societatis Botanicorum Poloniae 55, no. 4 (2014): 629–37. http://dx.doi.org/10.5586/asbp.1986.052.

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Sesquiterpene lactones were found to occur in all of the studied species of the subgenus <em>Psephellus</em> (Cass.) Schmalh. Differing compositions were found in the representatives of three sections. In <em>Centaurea declinata</em> MB. from the section <em>Leucophylle</em> (Sosn.) Sosn.. 15-deoxyrepin, linichlorin B and cynaropicrin were found. Linichlorin B dominated in <em>Centaurea hypoleucu</em> DC. from section <em>Hypoleucae</em> (Sosn.) Sosn., while in the species classified in section <em>Psephellus</em> Sosn., r
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Abbas, Ghada M., Amal Sallam, Fatma M. Abdel Bar, Mohamed Farid I. Lahloub, and Ahmed A. Gohar. "New Cynaropicrin Derivative from Cynara Scolymus L." Records of Natural Products 15, no. 2 (2020): 103–10. http://dx.doi.org/10.25135/rnp.198.20.07.1747.

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A new sesquiterpene lactone 1a along with other four known compounds 1b, 2, 3 and 4 were isolated from fresh leaves of Cynara scolymus L. using ordinary chromatographic techniques. The structures of the isolated compounds were determined via spectroscopic analysis.
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Nowak, Gerard, Bohdan Drożdż, and Miroslav Holub. "Sesquiterpene lactones. XXXII. Guaianolides in species from the genus Chartolepis Cass." Acta Societatis Botanicorum Poloniae 55, no. 2 (2014): 233–38. http://dx.doi.org/10.5586/asbp.1986.023.

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Differences in the composition of the "lactone fraction" of 4 species from the genus <em>Chartolepis</em> Cass. were observed. Cynaropierin was isolated from the above-ground parts of <em>Chartolepis intermedia</em> Boiss. and the occurrence there of grossheimin was confirmed. The following compounds were isolated from the above-ground parts of <em>Chartolepis glastifolia</em> (L.) Cass.: centaurepensin, repin, cebellin C, acroptillin, cebellin D, cynaropicrin, cebellin F and janerin. Centaurepensin, repin, cebellin C, acroptillin, cynaropicrin, janerin and
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Baybulova, A., V. Bychkov, S. Kulikova , S. Lazarev, R. Uruzbaev , and V. Korsun. "Studying of sausalin and cynaropicrin in experimental opisthorchosis." Immunopathology, Allergology, Infectology, no. 3 (July 1, 2016): 70–76. http://dx.doi.org/10.14427/jipai.2016.3.70.

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Dissertations / Theses on the topic "Cynaropicrin"

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Brás, Teresa Isabel de Amoreira Sousa e. Silva. "Production of cynaropicrin extracts from Cynara cardunculus leaves and its use for development of wound dressing films." Doctoral thesis, 2020. http://hdl.handle.net/10362/111454.

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Natural compounds derived from plants are presently an alternative for the discovery of new effective drugs, from which new products may be developed, potentially overcoming the current limitations of synthetic compounds for use in pharma and biomedical applications. This thesis concerns the design and production of cynaropicrin enriched extracts from leaves of Cynara cardunculus, and their application in a chitosan matrix as wound dressing for antiinflammatory drug delivery. The design and production of cynaropicrin enriched extracts was performed considering the use of environmentally
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Coelho, Maria da Conceição Rijo Dragão Lopes. "Avaliação de populações espontâneas de CARDO-DO-COALHO (CYNARA CARDUNCULUS) - numa perspectiva de valorização da espécie." Master's thesis, 2019. http://hdl.handle.net/10400.26/28691.

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Cynara cardunculus é uma planta espontânea, que tradicionalmente é utilizada para o fabrico de queijo. No entanto, apresenta outras potencialidades que podem gerar valor acrescentado. A planta é uma fonte de cinaropicrina (principal componente do conteúdo lipofílico das folhas) que influência as atividades fisiológicas ou celulares dos seres vivos que as consomem. O presente trabalho teve como objetivo descrever a variabilidade fenotípica de populações silvestres de Cynara cardunculus existentes no Alto e Baixo Alentejo, avaliando, simultaneamente, se existe alguma relação entre os descritore
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Book chapters on the topic "Cynaropicrin"

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Caroleo, Maria Cristina, Francesca Aiello, Erika Cione, and Maria Luisa Di Gioia. "Sesquiterpene Lactone Cynaropicrin as Novel Inhibitor of Bcr-Abl Fusion Oncogene Expression." In Frontiers in Natural Product Chemistry. BENTHAM SCIENCE PUBLISHERS, 2019. http://dx.doi.org/10.2174/9789811423772119050004.

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