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Journal articles on the topic 'Derivatives of Salicylic Acid'

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Published: 5 June 2025

Last updated: 1 August 2025

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1

Bondareva, Natalia A., Peotr P. Purygin, and Olga O. Isaeva. "Synthesis and biological activity of a number of salicylic acid esters." Butlerov Communications 60, no. 11 (2019): 93–97. http://dx.doi.org/10.37952/roi-jbc-01/19-60-11-93.

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Salicylic acid is currently of little use, but its derivatives are one of the most large-tonnage drugs in the world. However, the natural sources of salicylic acid cannot satisfy the needs for its preparations and therefore the acid and its derivatives are obtained exclusively by synthetic means. Derivatives of salicylic acid are of great interest, due to their high reactivity and widespread use in medical practice as anti-inflammatory, antipyretic, analgesic, antimicrobial, antiseptic and anti-tuberculosis drugs. Currently, there is a fairly large body of data on the synthesis, structure, and

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2

Chvertkina, L. V., P. S. Khoklov, and Vladimir F. Mironov. "Phosphorus derivatives of salicylic acid." Russian Chemical Reviews 61, no. 10 (1992): 1009–21. http://dx.doi.org/10.1070/rc1992v061n10abeh001013.

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3

Prithiviraj, B., U. P. Singh, M. Manickam, and A. B. Ray. "Antifungal activity of anacardic acid, a naturally occurring derivative of salicylic acid." Canadian Journal of Botany 75, no. 1 (1997): 207–11. http://dx.doi.org/10.1139/b97-021.

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The antifungal activity of anacardic acid and two of its derivatives was tested against some plant pathogenic fungi and the inhibitory effect was compared with that of salicylic acid. Anacardic acid was found to be most effective and it inhibited Colletotrichum capsici spore germination at 125–150 μg mL−1. The results suggest that salicylic acid with appropriate structural modifications may prove to be a superior antifungal agent and can be utilized in controlling certain plant diseases under field conditions. Key words: salicylic acid derivatives, antifungal activity, fungal spore germination

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4

Mardjan, Muhammad Idham Darussalam, Retno Ambarwati, Sabirin Matsjeh, Tutik Dwi Wahyuningsih, and Winarto Haryadi. "SYNTHESIS OF FLAVANONE-6-CARBOXYLIC ACID DERIVATIVES FROM SALICYLIC ACID DERIVATIVE." Indonesian Journal of Chemistry 12, no. 1 (2012): 70–76. http://dx.doi.org/10.22146/ijc.21374.

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Synthesis of flavanone-6-carboxylic acid derivatives had been conducted via the route of chalcone. The synthesis was carried out from salicylic acid derivative, i.e. 4-hydroxybenzoic acid, via esterification, Fries rearrangement, Claisen-Schmidt condensation and 1,4-nucleophilic addition reactions. Structure elucidation of products was performed using FT-IR, 1H-NMR, GC-MS and UV-Vis spectrometers. Reaction of 4-hydroxybenzoic acid with methanol catalyzed with sulfuric acid produced methyl 4-hydroxybenzoate in 87% yield. The acid-catalyzed-acetylation of the product using acetic anhydride gave

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5

A., A. ABD EL-GABER, B. SALEH M., and T. AHMED I. "Potentiometric Studies on the Ternary Complex Systems : Metal(II)-Salicylic Acid-Amino Acids." Journal of Indian Chemical Society Vol. 69, Jan 1992 (1992): 17–20. https://doi.org/10.5281/zenodo.5991402.

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Chemistry Department, Faculty of Science, Minia University, Minia, Egypt <em>Manuscript received 26 March 1991, revised 28 October 1991, accepted 27 January 1992</em> Ternary complex systems, metal(II)-salicylic acid derivatives (as primary ligands)-acidic and basic amino acids (as secondary ligands) have been investigated by the potentiometric technique. Formation constant values of the various binary and ternary complexes liable to exist in such systems have been determined at 25° and µ=0.2 mol dm<sup>-3</sup> (KCI). The order of stability of the binary or ternary complexes in

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6

Enchev, Dobromir D. "New Phosphorus Derivatives of Salicylic Acid." Phosphorus, Sulfur, and Silicon and the Related Elements 165, no. 1 (2000): 243–48. http://dx.doi.org/10.1080/10426500008076343.

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7

Fatullayeva, P. A. "COMPLEXES OF METALS WITH HYDRAZONE HYDRAZIDE SALICYLIC ACID." Chemical Problems 19, no. 2 (2021): 79–83. http://dx.doi.org/10.32737/2221-8688-2021-2-79-83.

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Complexes of Cu (II), Ni (II), and Co (II) with hydrazone derivatives of salicylic acid hydrazide and 3,5-di-tert-butyl salicylic aldehyde (LH) were synthesized and the structure of these compounds studied by means of elemental analysis methods, IR and electronic spectroscopy, magnetochemistry and thermal analysis. It revealed that the complexes are monomeric and have a composition [MLXSoI] where M is a metal ion, L is a ligand, X is an inorganic anion, and Sol is a solvent molecule. LH- in the complexes behaves like a monoanionic tridentate ligand. It found that the resulting complexes exhibi

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8

Divya Nair, Vadakkemuriyil, Sreedevi, Pathaniya Reeya, Diksha, Khem Chand Saini, and Kumar Sanjeev. "COMPARATIVE STUDY ON AMELIORATIVE EFFECT OF SALICYLIC ACID AND ITS DERIVATIVES IN F1 HYBRID, INDAM NAVEEN 2000 VARIETY OF LYCOPERSICUM ESCULENTUM MILL. UNDER SALINITY STRESS." International Journal on Agricultural Sciences 15, no. 02 (2024): 63–83. https://doi.org/10.53390/ijas.2024.15201.

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Agriculture productivity is severely hampered by salinity of the soil. To increase plant salinity tolerance, a variety of tactics have been used. The use of salicylic acid (SA) to promote plant salt tolerance has been widely reported. Biologically active salicylic acid (SA) derivative (Sulfosalicyclic acid, SSA) and SA were chosen to study their ameliorative effect of salt stress in Solanum esculentum mill. Indo –American Hybrid Seeds F1 Hybrid, Indam Naveen 2000 variety were used in this study. The compounds were applied as soil drenching method. Under 100mM NaCl treatment the growth paramete

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9

Clissold, Stephen P. "Aspirin and Related Derivatives of Salicylic Acid." Drugs 32, Supplement 4 (1986): 8–26. http://dx.doi.org/10.2165/00003495-198600324-00003.

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10

Capelle, S., N. Cotelle, P. Cotelle, J. L. Bernier, and J. P. Catteau. "Antioxidant activities of dihydroxylated salicylic acid derivatives." Redox Report 1, no. 2 (1995): 131–37. http://dx.doi.org/10.1080/13510002.1995.11746971.

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11

Rahman, M. Mukhlesur, Satyajit D. Sarker, Maureen Byres, and Alexander I. Gray. "New Salicylic Acid and Isoflavone Derivatives fromFlemingiapaniculata." Journal of Natural Products 67, no. 3 (2004): 402–6. http://dx.doi.org/10.1021/np0206108.

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12

Dhanapal, L. P., and A. N. Morse. "Effect of analgesics and their derivatives on antibiotic resistance of environmental microbes." Water Science and Technology 59, no. 9 (2009): 1823–29. http://dx.doi.org/10.2166/wst.2009.210.

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This research is a preliminary study conducted to determine the effects of aspirin (acetyl-salicylic acid) and salicylic acid (analgesics and their derivatives) on the antibiotic resistance of ammonia oxidizing bacterium (AOB) (a non-pathogenic environmental microbe) cultured from the Texas Tech University—Water Recovery System that treats a space related wastewater for NASA. The effect of salicylic acid was investigated by obtaining the minimal inhibition concentration (MIC) of antibiotics (amoxicillin, ciprofloxacin, and nalidixic acid) in the presence of aspirin and salicylic acid. The poss

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13

Kachalkin, Maxim N., and Alexander V. Voronin. "Preparation of sorbents for solid-phase extraction of salicylic acid from aqueous solutions." Aspirantskiy Vestnik Povolzhiya 21, no. 5-6 (2021): 16–22. http://dx.doi.org/10.55531/2072-2354.2021.21.3.16-22.

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Salicylic acid and its derivatives are widely used in medicine and pharmacy as antipyretic, antirheumatic, anti-inflammatory and analgesic drugs for external and internal use. The development of methods for the quantitation of salicylic acid in multicomponent samples using selective methods of sample preparation is an important problem in quality drug control. The aim of the study was to obtain sorbents based on ethyl cellulose for solid-phase extraction of salicylic acid from aqueous solutions. As a result of the study, a method for obtaining a sorbent for solid-phase salicylic acid from aque

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14

Yu, Byung Sul, Eui Chaul Oh, and Dong Hwan Sohn. "Molecular interaction between a reduced riboflavin derivative and salicylic acid derivatives." Archives of Pharmacal Research 8, no. 3 (1985): 99–107. http://dx.doi.org/10.1007/bf02857035.

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15

Xu, Qiuyang, Meixue Shi, Shaohua Wang, and Yuchun Qing. "Study on the Effect of Exogenous Salicylic Acid on Algae Growth in the Environment." E3S Web of Conferences 165 (2020): 02001. http://dx.doi.org/10.1051/e3sconf/202016502001.

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With the development of industry, synthetic drugs and their secondary metabolites bring some hidden dangers to environmental safety. As an excellent drug, salicylic acid is widely used in cardiovascular drugs, industrial dyes, skin care and acne products, etc. Therefore, it is possible to detect salicylic acid molecules, its derivatives or secondary metabolites in the natural environment. It should be noted that salicylic acid, as an endogenous signal molecule, can greatly affect plant growth. In this study, the common algal Spirogyra in fresh water was taken as the research object. The effect

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16

Meher, Hari Charan, Vijay T. Gajbhiye та Ghanendra Singh. "A GC-ECD Method for Estimation of Free and Bound Amino Acids, γ-Aminobutyric Acid, Salicylic Acid, and Acetyl Salicylic Acid from Solanum lycopersicum (L.)". Journal of AOAC INTERNATIONAL 94, № 1 (2011): 232–42. http://dx.doi.org/10.1093/jaoac/94.1.232.

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Abstract A gas chromatograph with electron capture detection method for estimation of selected metabolites—amino acids (free and bound), γ-aminobutyric acid (GABA), salicylic acid (SA), and acetyl salicylic acid (ASA) from tomato—is reported. The method is based on nitrophenylation of the metabolites by 1-fluoro-2,4-dinitrobenzene under aqueous alkaline conditions to form dinitrophenyl derivatives. The derivatives were stable under the operating conditions of GC. Analysis of bound amino acids comprised perchloric acid precipitation of protein, alkylation (carboxymethylation) with iodoacetic ac

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17

Pan, Bendu, Jia-Sheng Ouyang, Yaqi Zhang, et al. "Iridium-catalyzed intramolecular asymmetric allylic etherification of salicylic acid derivatives with chiral-bridged biphenyl phosphoramidite ligands." Organic Chemistry Frontiers 8, no. 16 (2021): 4514–19. http://dx.doi.org/10.1039/d1qo00566a.

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18

Nayfert, S. A., D. A. Zherebtsov, K. Rajakumar, et al. "Structure of Two Acetylene Derivatives of Salicylic Acid." Crystallography Reports 67, no. 3 (2022): 364–70. http://dx.doi.org/10.1134/s1063774522030142.

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19

Ukrainczyk, Marko, Matija Gredičak, Ivanka Jerić, and Damir Kralj. "Interactions of salicylic acid derivatives with calcite crystals." Journal of Colloid and Interface Science 365, no. 1 (2012): 296–307. http://dx.doi.org/10.1016/j.jcis.2011.09.009.

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20

Nicktam, Thokchom, Chenu Sri Likhitha, Roshnee Nameirakpam, and Jatinder Singh. "Enhancement of Postharvest Life of Fruits by Application of Salicylic Acid." International Journal of Plant & Soil Science 35, no. 10 (2023): 15–22. http://dx.doi.org/10.9734/ijpss/2023/v35i102919.

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Salicylic acid (SA), an endogenous plant growth regulator, has been found to produce a wide range of metabolic and physiological responses in plants thereby affecting their growth and development. SA as a natural and safe phenolic compound, which exhibits a high potential in controlling postharvest losses of fruit crops. In this review, various intrinsic biosynthetic pathways and effects of exogenous salicylic acid on respiration, antioxidant systems, ethylene biosynthesis action, oxidative stress, nutritional quality, firmness, disease resistance and postharvest decay have also been discussed

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21

George, Roy. "Adsorption Equilibrium and Kinetic Studies of Effect of ortho-Substitution to Benzoic Acid in Aqueous Phase Using Granular Activated Carbon." Asian Journal of Chemistry 31, no. 8 (2019): 1667–74. http://dx.doi.org/10.14233/ajchem.2019.21938.

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Adsorption equilibrium and kinetics studies of effect of ortho-substituted benzoic acid in aqueous phase using granular activated carbon were investigated. The granular activated carbon (GAC) obtained from bituminous type coal having a surface area of 998 m2/g and loosely bounded and open pores morphology. The adorbates selected for this study was benzoic acid and its ortho-derivatives namely; salicylic acid, phthalic acid and o-toluic acid. The solubility of adsorbate in solvent affected the adsorption behaviour more pronouncly. The order of adsorption for adsorbates was found to be as: benzo

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22

Kuzma, Mónika, Nikoletta Kovács, Lilla Sziva, Gábor Maász, Péter Avar, and Pál Perjési. "Oxidation of Hydroxy- and Dihydroxybenzoic Acids Under the Udenfriend's Conditions. An HPLC Study." Open Medicinal Chemistry Journal 12, no. 1 (2018): 13–22. http://dx.doi.org/10.2174/1874104501812010013.

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Background:Non-enzymatic hydroxylation of aromatic compounds to the respective phenolic derivatives is a possible metabolic pathway of xenobiotics. The formed metabolites can undergo consecutive oxidative reactions with free radicals to form potential toxic molecules.Objective:Development of HPLC methods to separate, identify and quantitate the main products formed from salicylic acid, 2,3-dihydroxybenzoic acid and 2,5-dihydroxybenzoic acid underin vitrohydroxylation conditions (Udenfriend's system).Method:An RP-HPLC-UV-Vis method was developed to separate salicylic acid and isomeric dihydroxy

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23

Hooper, Abigail E., Stuart R. Kennedy, Christopher D. Jones, and Jonathan W. Steed. "Gelation by supramolecular dimerization of mono(urea)s." Chemical Communications 52, no. 1 (2016): 198–201. http://dx.doi.org/10.1039/c5cc06995e.

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24

Oliveira, Ana Júlia de Morais Santos, Tatiana Pineda, Sara Maria Robledo, and Damião Pergentino De Sousa. "Antiparasitic evaluation of salicylate and salicylamide derivatives." Brazilian Journal of Health Review 6, no. 4 (2023): 15959–76. http://dx.doi.org/10.34119/bjhrv6n4-156.

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In the present study, twelve salicylic acid derivatives were obtained through Fischer esterification, the Mitsunobu reaction, and the acid chloride reactions. The products were structurally characterized using infrared, 1H NMR, 13C NMR spectroscopy, and high resolution mass spectrometry of three unpublished compounds. Then they were evaluated against the parasites Leishmania braziliensis, Trypanosoma cruzi, and Plasmodium falciparum. Some compounds were weakly bioactive against L. braziliensis amastigotes, such as N-cyclohexyl-2-hydroxybenzamide (10), EC50 = 15.60 ± 2.69 µM and SI = 2.67, and

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25

Aksoy, Mehmet Suat, and Ulviye Özer. "Equilibrium Studies on Chromium(III) Complexes of Salicylic Acid and Salicylic Acid Derivatives in Aqueous Solution." CHEMICAL & PHARMACEUTICAL BULLETIN 52, no. 11 (2004): 1280–84. http://dx.doi.org/10.1248/cpb.52.1280.

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26

Nehela, Yasser, Naglaa A. Taha, Abdelnaser A. Elzaawely, et al. "Benzoic Acid and Its Hydroxylated Derivatives Suppress Early Blight of Tomato (Alternaria solani) via the Induction of Salicylic Acid Biosynthesis and Enzymatic and Nonenzymatic Antioxidant Defense Machinery." Journal of Fungi 7, no. 8 (2021): 663. http://dx.doi.org/10.3390/jof7080663.

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Tomato early blight, caused by Alternaria solani, is a destructive foliar fungal disease. Herein, the potential defensive roles of benzoic acid (BA) and two of its hydroxylated derivatives, ρ-hydroxybenzoic acid (HBA), and protocatechuic acid (PCA) against A. solani were investigated. All tested compounds showed strong dose-dependent fungistatic activity against A. solani and significantly reduced the disease development. Benzoic acid, and its hydroxylated derivatives, enhanced vegetative growth and yield traits. Moreover, BA and its derivatives induce the activation of enzymatic (POX, PPO, CA

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27

Ramesh, Aswathy, Rakesh Kumar Jat, and R. Arunkumar. "Synthesis and Evaluation of Antifungal Activity of Novel 1,3,4-Oxadiazole Derivatives." International Journal of Medical Sciences and Pharma Research 10, no. 1 (2024): 22–25. http://dx.doi.org/10.22270/ijmspr.v10i1.85.

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Here new eight derivatives of 1,3,4-oxadiazole were synthesised from salicylic acid and phenyl acetic acid by ring condensation mechanism. The synthesized derivatives were characterized and structures were confirmed by various spectral analysis. Antifungal activity studies revealed that Ox1, Ox2 and Ox4 exhibit promising activity. Keywords: 1,3,4-oxadiazole, antifungal activity, Disc diffusion method, MIC,

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28

Kumar, N., and D. Pathak. "SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SOME NEWER BENZIMIDAZOLE DERIVATIVES BY MANNICH REACTION." INDIAN DRUGS 56, no. 07 (2019): 16–22. http://dx.doi.org/10.53879/id.56.07.11797.

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O-phenylenediamine and salicylic acid were used for the synthesis of 2-(1-(substituted phenylamino) methyl-1H benzo[d] imidazol-2-yl) phenol (2a-2h) derivatives by using various substituted aniline. In the first step, reaction of o-phenylenediamine and salicylic acid yielded 2-(1H-benzo[d]imidazol-2-yl) phenol (1), which on Mannich reaction with substituted aniline gave compounds (2a-2h). The structures of these compounds were characterized by IR, 1H NMR, mass spectral data and elemental analysis. Each analogue was tested in vitro for various types of pharmacological activity of this class of

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29

Luňák, Stanislav, Jacques Muzart, and Jiřina Brodilová. "Photochemical Hydroxylation of Salicylic Acid Derivatives with Hydrogen Peroxide, Catalyzed with Fe(III) and Sensitized with Methylene Blue." Collection of Czechoslovak Chemical Communications 59, no. 4 (1994): 905–12. http://dx.doi.org/10.1135/cccc19940905.

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Substitution of hydrogen in the carboxy or hydroxy group of a salicylic acid molecule with a methyl group, which hinders the coordination of Fe(III), results in a pronounced reduction of photocatalytic effects. The complex of Fe(III) with salicylic acid is the precursor of the thermal catalyst arising on irradiation.

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30

Takahashi, Shigehiro, Nobuhiro Haraguchi, Naoyuki Abiko, Tetsuya Ono, Kentaro Yoshida, and Jun-Ichi Anzai. "Voltammetric Determination of Salicylic Acid and Derivatives Based on Ferroceneboronic Acid." Sensor Letters 9, no. 5 (2011): 1845–48. http://dx.doi.org/10.1166/sl.2011.1737.

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31

Wodnicka, Alicja, Elżbieta Huzar, Maria Krawczyk, and Halina Kwiecień. "Synthesis and antifungal activity of new salicylic acid derivatives." Polish Journal of Chemical Technology 19, no. 1 (2017): 143–48. http://dx.doi.org/10.1515/pjct-2017-0019.

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Abstract A simple one-step procedure for synthesis of 1-methoxy-1-oxoalkan-2-yl salicylates and 1-methoxy-1-oxoalkan-2-yl 2-[(1-methoxy-1-oxoalkan-2-yl)oxy]benzoates by reaction of salicylic acid with several methyl 2-bromoalkanoates was developed. The reactions were carried out in N,N-dimethylformamide (DMF) in the presence of anhydrous potassium carbonate. Conditions for regioselective synthesis of target compounds were established. The developed procedure could be easily applied in the industrial production process. The new salicylic acid derivatives were obtained with satisfactory yields a

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32

Wu, Qi-Fan, Bin Zhao, Zhi-Jin Fan, et al. "Design, synthesis and fungicidal activity of isothiazole–thiazole derivatives." RSC Advances 8, no. 69 (2018): 39593–601. http://dx.doi.org/10.1039/c8ra07619g.

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33

F. Saeed, Zenab. "Synthesis of some Acetylenic Amino Derivatives from Salicylic Acid." JOURNAL OF EDUCATION AND SCIENCE 23, no. 3 (2010): 48–53. http://dx.doi.org/10.33899/edusj.2010.58408.

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34

Toiu, A., L. Vlase, I. Oniga, and M. Tamas. "HPLC analysis of salicylic acid derivatives from Viola species." Chemistry of Natural Compounds 44, no. 3 (2008): 357–58. http://dx.doi.org/10.1007/s10600-008-9060-9.

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35

Xu, G. L., Z. Z. Liu, M. Xie, et al. "Salicylic Acid Derivatives and Other Components from Gaultheria trichoclada." Chemistry of Natural Compounds 52, no. 2 (2016): 301–3. http://dx.doi.org/10.1007/s10600-016-1621-8.

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36

CHVERTKINA, L. V., P. S. KHOKHLOV, and V. F. MIRONOV. "ChemInform Abstract: Chemistry of Phosphorus Derivatives of Salicylic Acid." ChemInform 24, no. 44 (2010): no. http://dx.doi.org/10.1002/chin.199344311.

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37

Lisina, S. V., A. K. Brel’, L. S. Mazanova, and A. A. Spasov. "Synthesis and antipyretic activity of new salicylic acid derivatives." Pharmaceutical Chemistry Journal 42, no. 10 (2008): 574–76. http://dx.doi.org/10.1007/s11094-009-0184-4.

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38

Pozdnyakov, Ivan P., Anatolio Pigliucci, Nikolai Tkachenko, Victor F. Plyusnin, Eric Vauthey, and Helge Lemmetyinen. "The photophysics of salicylic acid derivatives in aqueous solution." Journal of Physical Organic Chemistry 22, no. 5 (2009): 449–54. http://dx.doi.org/10.1002/poc.1489.

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Ledwożyw-Smoleń, Iwona, Mariya Halka, Sylwester Smoleń, and Michał Kruczek. "ANTIOXIDANT POTENTIAL OF TOMATO (SOLANUM LYCOPERSICUM L.) SEEDLINGS AS AFFECTED BY THE EXOGENOUS APPLICATION OF ORGANOIODINE COMPOUNDS." Acta Scientiarum Polonorum Hortorum Cultus 19, no. 2 (2020): 3–15. http://dx.doi.org/10.24326/asphc.2020.2.1.

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Salicylic acid is one of the regulatory compounds involved in numerous processes in plants. Previous studies indicated that also its halogen derivatives may exhibit similar roles. The aim of the work was to evaluate the influence of iododerivatives of salicylic acid such as: 5-iodosalicylc acid (5I-SA) and 3,5-diiodosalicylic acid (3,5diI-SA) on selected aspects of antioxidant capacity of tomato seedlings. The efficiency of improving iodine accumulation in tomato seedlings was also studied. No tested organoiodine compound had a negative effect on the growth and development of tomato seedlings.

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40

Nitulescu, Georgiana, Dumitru Lupuliasa, Ines Adam-Dima, and George Mihai Nitulescu. "Ultraviolet Filters for Cosmetic Applications." Cosmetics 10, no. 4 (2023): 101. http://dx.doi.org/10.3390/cosmetics10040101.

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Sunscreens reduce the occurrence risk of skin disorders such as sunburn, skin aging, and cancer through their ability to absorb, reflect, and scatter ultraviolet (UV) radiation. This review provides an overview of UV filters as active ingredients of sunscreen products, emphasizing their classification and structural characteristics. Their photostability, mechanism of action of ultraviolet radiation absorption, optical properties, and regulatory status are discussed based on their chemical structure. The main classes of organic UV filters presented include aminobenzoic acid derivatives, salicyl

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41

Cecone, Claudio, Mario Iudici, Marco Ginepro, Marco Zanetti, Francesco Trotta, and Pierangiola Bracco. "Dextrin-Based Adsorbents Synthesized via a Sustainable Approach for the Removal of Salicylic Acid from Water." Nanomaterials 13, no. 20 (2023): 2805. http://dx.doi.org/10.3390/nano13202805.

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Pharmaceuticals such as salicylic acid are commonly detected in wastewater and surface waters, increasing concern for possible harmful effects on humans and the environment. Their difficult removal via conventional treatments raised the need for improved strategies, among which the development of bioderived adsorbents gained interest because of their sustainability and circularity. In this work, biobased cross-linked adsorbents, synthesized via a sustainable approach from starch derivatives, namely beta-cyclodextrins and maltodextrins, were at first characterized via FTIR-ATR, TGA, SEM, and el

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42

El-Hagrassey, Eman A., Ehab Abdel-Latif, and Gamal M. Abdel-Fattah. "Synthesis and efficiency of new pyridine, chromene and thiazole containing compounds as antimicrobial and antioxidant agents." Bulletin of the Chemical Society of Ethiopia 36, no. 1 (2022): 137–48. http://dx.doi.org/10.4314/bcse.v36i1.12.

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ABSTRACT. The versatile scaffold, N'-(2-cyanoacetyl)-2-hydroxybenzohydrazide (3) was utilized in the production of new pyridine, chromene and thiazole derivatives as antimicrobial and antioxidant agents. The synthetic strategy involves the treatment of precursor 3 with various arylidene-malononitrile and 3-aryl-2-cyanoacrylate compounds to furnish substituted pyridines 5 and 7. The interaction of 3 with salicylaldehyde and/or phenyl isothiocyanate followed by cyclization with chloroacetone produced the corresponding 2-imino-2H-chromene-3-carbohydrazide and (thiazol-2-ylidene-acetyl)-salicylic

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43

Agarwal, Sarah. "A New Approach Towards Cancer Cures: Salicylic Acids and its Derivatives." International Journal of Science and Research (IJSR) 14, no. 1 (2025): 232–39. https://doi.org/10.21275/sr241119144136.

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Pniewska, Alicja, and Urszula Kalinowska-Lis. "A Survey of UV Filters Used in Sunscreen Cosmetics." Applied Sciences 14, no. 8 (2024): 3302. http://dx.doi.org/10.3390/app14083302.

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The aim of this study was to determine the types of UV filters used in adult and children’s sunscreen products sold in Poland (part of the EU market) and their frequency of use. The INCI compositions of sunscreen products were collected and analyzed for the presence of UV filters. The study included 150 randomly selected preparations for adults (from 71 brands) and 50 for children (from 33 brands). The survey concerned the UV filters listed in Annex VI to Regulation (EC) No 1223/2009 of the European Parliament and Council of 30 November 2009 on cosmetic products. The most frequently used UV fi

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Akshara, Vinayakrishnan* Aneesha Thomas Malavika K. Aswagosh K. "In-Silico Design, Synthesis and Biological Evaluation of Some Noval Benzimidazole Derivatives." International Journal of Pharmaceutical Sciences 3, no. 2 (2025): 1493–504. https://doi.org/10.5281/zenodo.14886450.

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Benzimidazole, a heterocyclic compound with versatile biological activity, serves as a scaffold for medicinal chemistry. We aimed to develop new derivatives with anti-inflammatory and anti-bacterial effects. The design was done using software tools, followed by synthesis, isolation, purification and characterization of two derivatives. The two novel derivatives are synthesized by the reaction of benzimidazole with 5-sulphosalicylic acid (BM 1) and 3,5-dinitro salicylic acid(BM 2). Biological activity was evaluated using protein denaturation and agar well diffusion method. The results showed th

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Volgina, Tatyana, Viktor T. Novikov, and Oksana Yu Fedorova. "Liquid-Phase Oxidative Degradation of the Damaged or Expired Medicinal Products." Advanced Materials Research 1040 (September 2014): 327–30. http://dx.doi.org/10.4028/www.scientific.net/amr.1040.327.

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A method of oxidative mineralization of the salicylic acid and its derivatives as well as medicinal products containing salicylic acid as the active ingredient was investigated. Destruction of the organic compounds is possible both in the electrolyte under the oxidant, electrochemically formed in situ in the sulphuric acid solutions, and at the anode so. Simultaneously, at the cathode, reduction of the zinc ions, contained in a number of medicinal products, is possible. Final products of the oxidation are simple non-toxic organic compounds, carbon dioxide, and water. This process is the most e

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KRISHNA, C. JOSHI, JAIN RENUKA, and NISHITH SAROJ. "Reactions of 3-Arylimino-2H-indol-2-ones with o-Mercaptobenzoic Acid and Salicylic Acid : Synthesis of Novel Spiro[2H-1,3-benzothiazine-2,3'-[3H]indole]-2,4( 1' H,3H)-diones." Journal of Indian Chemical Society Vol. 68, Nov 1991 (1991): 625–27. https://doi.org/10.5281/zenodo.6154499.

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Department of Chemistry, University of Rajasthan, Jaipur-302 004 <em>Manuscript received 6 March 1991, accepted 7 November 1991</em> Reactions of 3-Arylimino-2<em>H</em>-indol-2-ones with o-Mercaptobenzoic Acid and Salicylic Acid : Synthesis of Novel Spiro[2<em>H</em>-1,3-benzothiazine-2,3'-[3<em>H</em>]indole]-2,4( 1' H, 3<em>H</em>)-diones.

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Rajesh, K. Verma, and Chaurasia Leena. "Synthesis and antifungal activity studies of some pyrazolopyrimidine derivatives." Journal of Indian Chemical Society Vol. 82, Jul 2005 (2005): 665–69. https://doi.org/10.5281/zenodo.5830592.

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Building Pests and Mycology Laboratory, Environmental Science and Technology Division. Central Building Research Institute, Roorkee-247 667, India <em>E-mail</em> : rkverma_cbri@yahoo.co.in;      dr_rajesh 197S @rediffmail.com <em>Manuscript received 20 July 2004, revised 5 January 2005, accepted 22 March 2005</em> Thirty four compounds of pyrazolopyrimidine derivatives namely N<sup>1</sup>-isonicotinoyi/<em>N<sup>1</sup></em>-salicyloyl-4'-(substituted phenylazo) 1,2-diazole-4,6-dimethyl pyrimidine-5-one have been synthesized by the condensation of substituted phenylaz

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Ramesh, Aswathy, Rakesh Kumar Jat, and R. Arunkumar. "Pharmacological Evaluation of Novel 1,3,4-Oxadiazole Derivatives." International Journal of Medical Sciences and Pharma Research 10, no. 1 (2024): 26–34. http://dx.doi.org/10.22270/ijmspr.v10i1.88.

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A series of 2, 5- disubstituted- 1, 3, 4-oxadiazole derivatives (Ox1-Ox10) are synthesized by the ring condensation reaction followed by rearrangement of salicylic acid and phenyl acetic acid with various aromatic acids in presence of phosphorous oxychloride as cyclizing agent. Structure of the new derivatives are confirmed by spectral analysis. Those derivatives having high Pa value in PASS software are subjected to antibacterial, anticancer and antidiabetic studies which yield promising reports. This study helps and stimulate the researcher to exploit the oxadiazole nuclei for the developmen

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Li, Anlan, Hubert Seipelt, Cornelia Müller, Yongde Shi, and Gerhard Michael Artmann. "Effects of Salicylic Acid Derivatives on Red Blood Cell Membranes." Pharmacology & Toxicology 85 (September 1999): 206–11. http://dx.doi.org/10.1111/j.1600-0773.1999.tb02010.x.

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