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Barbirotta, Marcello, Abdallah Cheikh, Antonio Mastrandrea, Francesco Menichelli, Marco Ottavi, and Mauro Olivieri. "Evaluation of Dynamic Triple Modular Redundancy in an Interleaved-Multi-Threading RISC-V Core." Journal of Low Power Electronics and Applications 13, no. 1 (2022): 2. http://dx.doi.org/10.3390/jlpea13010002.
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Functional safety is a key requirement in several application domains in which microprocessors are an essential part. A number of redundancy techniques have been developed with the common purpose of protecting circuits against single event upset (SEU) faults. In microprocessors, functional redundancy may be achieved through multi-core or simultaneous-multi-threading architectures, with techniques that are broadly classifiable as Double Modular Redundancy (DMR) and Triple Modular Redundancy (TMR), involving the duplication or triplication of architecture units, respectively. RISC-V plays an interesting role in this context for its inherent extendability and the availability of open-source microarchitecture designs. In this work, we present a novel way to exploit the advantages of both DMR and TMR techniques in an Interleaved-Multi-Threading (IMT) microprocessor architecture, leveraging its replicated threads for redundancy, and obtaining a system that can dynamically switch from DMR to TMR in the case of faults. We demonstrated the approach for a specific family of RISC-V cores, modifying the microarchitecture and proving its effectiveness with an extensive RTL fault-injection simulation campaign.
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Возіяну, В.А. "КОМПЛЕКСНА МЕТОДОЛОГІЯ ПОБУДОВИ DMR-АРХІТЕКТУРИ НА ОСНОВІ РАДІОСИСТЕМИ SDR". Наукові записки Львівського університету бізнесу та права. Серія економічна. Серія юридична, № 34 (30 вересня 2022): 186–93. https://doi.org/10.5281/zenodo.7274330.
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To date, the definition of the principles of the implementation of the open standard of digital mobile radio communication (DMR: Digital Mobile Radio) as a highly effective and simple approach to the organization of radio systems, which at the same time is characterized by low cost, is considered as an extremely urgent task of scientific research. Compared to such widespread universal standards as iDEN and TETRA, the architecture based on DMR is characterized by a multiple higher bandwidth of the information channel, backward compatibility, a wide toolkit for organizing a radio station based on modern components, as well as flexibility and scalability of the overall system by applying the method of time division of one physical radio communication channel (TDMA: Time Division Multiple Access). In this regard, for developing countries, the DMR standard remains the most relevant means of organizing radial-zone radio communication systems, on the basis of which the automatic distribution of communication channels between subscribers is carried out, which is considered as a stage of the global transition from analog to digital technologies. The purpose of the study is to build a structural diagram of the architecture of a radio communication system with a DMR architecture based on the USRP, which is regulated at the level of interaction between individual modules, respectively, performing modulation-demodulation operations, digital low-frequency filtering, and symbol synchronization. Within the framework of the study, an assessment of the effectiveness of modeling and the performance of the implementation of the DMR architecture on the correspondingly given model should also be given. The analysis of the basic approaches to the organization of the architecture of the modern radio system based on the standard of mobile radio communication DMR was carried out. The basic model of an architecturally organized set of network protocols of radio communication systems based on the DMR service is presented. A warehouse has been installed, on the basis of which it would be possible to create the model of the organization scheme of the SDR system used for radio communication based on the USRP platform. In accordance with the basic model, an analysis of the radio signal processing procedure was carried out through the construction of a functioning scheme of the organizational complex for the radio communication. Proposals can be used for the organization, scaling and optimization of the DPR architecture in accordance with the target indicators.
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Golander, A., S. Weiss, and R. Ronen. "Synchronizing Redundant Cores in a Dynamic DMR Multicore Architecture." IEEE Transactions on Circuits and Systems II: Express Briefs 56, no. 6 (2009): 474–78. http://dx.doi.org/10.1109/tcsii.2009.2020930.
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Makhlynets, N. P., V. P. Pyuryk, H. B. Prots, and N. Ya Slyusarenko. "Etiopathogenetic Treatment of Patients with Dentofacial Anomalies Against the Background of Disorders in the Architecture of the Oral Cavity Forecourt." DENTISTRY. MEDICINE. REHABILITATION, no. 1 (June 2025): 9–13. https://doi.org/10.64124/dmr-2025-1-9.
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Aim and objectives of the study: Improving the effectiveness of diagnostics and comprehensive treatment of patients with dentofacial anomalies against the background of disorders in the architecture of the vestibule of the mouth is relevant, as the frenula of the lips, tongue, and buccal frenula are among the etiological factors in the development of dentofacial anomalies and the cause of relapses after the completion of active orthodontic treatment. Materials and Methods of the Study: 60 individuals with dentofacial anomalies and disorders in the architecture of the oral cavity forecourt were examined and treated, with an important aspect being the plastic surgeries on the vestibule of the mouth. Patients in Groups 1A and 2A underwent plastic surgery for disorders in the architecture of the vestibule of the mouth using the classical method. Patients in Groups 1B and 2B received the proposed correction, where the wound healed by primary tension using palatal grafts. Scientific Novelty: The feature of the clinical course of dentofacial anomalies against the background of disorders in the architecture of the vestibule of the mouth was the pronounced changes in the architecture of the vestibule of the mouth (the height of the attachment of the lip frenulum was less than 5 mm, and in 85.0% (51⁄60) of patients, buccal frenula were present in the area of the incisors and premolars). The results of cytomorphometric and reographic studies indicated a deficiency in blood supply in these areas. The clinical and laboratory examination results showed a significant difference between surgical interventions, where the wound healed by primary and secondary tension. The long-term results after the proposed method of correcting disorders in the architecture of the vestibule of the mouth and the use of Gengigel in the postoperative period indicated the formation of a normotrophic scar, the absence of relapses and the formation of gingival recession in the projection areas of the buccal frenula, as well as the normalization of clinical and laboratory indicators. The obtained data significantly differ from the indicators in other patient groups (p < 0.05). Conclusions: A detailed examination of the oral cavity forecourt during treatment planning for patients with dentofacial anomalies is an important diagnostic component. Since abnormally fixed buccal frenula are often a prerequisite for changes in tooth position, disruption of blood supply in the areas where they are located, the appearance of gingival recessions, and hypertonia in the area of the circular muscle of the mouth. Preventive plastic surgery of the buccal frenula prevents the onset of these pathological conditions. The use of the technique we proposed, combined with the use of Gengigel in the postoperative period, ensures the formation of normotrophic scars and the restoration of blood supply in the vestibule of the mouth.
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MATSUKAWA, Go, Yohei NAKATA, Yasuo SUGURE, et al. "A Low-Latency DMR Architecture with Fast Checkpoint Recovery Scheme." IEICE Transactions on Electronics E98.C, no. 4 (2015): 333–39. http://dx.doi.org/10.1587/transele.e98.c.333.
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Mantzourani, Efi, Hamde Nazar, Catherine Phibben, et al. "Exploring the association of the discharge medicines review with patient hospital readmissions through national routine data linkage in Wales: a retrospective cohort study." BMJ Open 10, no. 2 (2020): e033551. http://dx.doi.org/10.1136/bmjopen-2019-033551.
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ObjectiveTo evaluate the association of the discharge medicines review (DMR) community pharmacy service with hospital readmissions through linking National Health Service data sets.DesignRetrospective cohort study.SettingAll hospitals and 703 community pharmacies across Wales.ParticipantsInpatients meeting the referral criteria for a community pharmacy DMR.InterventionsInformation related to the patient’s medication and hospital stay is provided to the community pharmacists on discharge from hospital, who undertake a two-part service involving medicines reconciliation and a medicine use review. To investigate the association of this DMR service with hospital readmission, a data linking process was undertaken across six national databases.Primary outcomeRate of hospital readmission within 90 days for patients with and without a DMR part 1 started.Secondary outcomeStrength of association of age decile, sex, deprivation decile, diagnostic grouping and DMR type (started or not started) with reduction in readmission within 90 days.Results1923 patients were referred for a DMR over a 13-month period (February 2017–April 2018). Provision of DMR was found to be the most significant attributing factor to reducing likelihood of 90-day readmission using χ2 testing and classification methods. Cox regression survival analysis demonstrated that those receiving the intervention had a lower hospital readmission rate at 40 days (p<0.000, HR: 0.59739, CI 0.5043 to 0.7076).ConclusionsDMR after a hospital discharge is associated with a reduction in risk of hospital readmission within 40 days. Linking data across disparate national data records is feasible but requires a complex processual architecture. There is a significant value for integrated informatics to improve continuity and coherency of care, and also to facilitate service optimisation, evaluation and evidenced-based practice.
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Mazumder, Dipayan, Mithun Datta, Alexander C. Bodoh, and Ashiq A. Sakib. "A Scalable Formal Framework for the Verification and Vulnerability Analysis of Redundancy-Based Error-Resilient Null Convention Logic Asynchronous Circuits." Journal of Low Power Electronics and Applications 14, no. 1 (2024): 5. http://dx.doi.org/10.3390/jlpea14010005.
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The increasing demand for high-speed, energy-efficient, and miniaturized electronics has led to significant challenges and compromises in the domain of conventional clock-based digital designs, most notably reduced circuit reliability, particularly in mission-critical hardware. At scaled technology nodes, devices are vulnerable to transient or soft errors, such as Single Event Upset (SEU) and Single Event Latch-up (SEL). External radiation, internal electromagnetic interference (EMI), or noise are the primary sources of these errors, which can compromise the circuit functionality. In response to these challenges, the Quasi-Delay-Insensitive (QDI) Null Convention Logic (NCL) asynchronous design paradigm has emerged as a promising alternative, offering advantages such as ultra-low power performance, reduced noise and EMI, and resilience to process, voltage, and temperature variations. Moreover, its unique architecture and insensitivity to timing variations offers a degree of resistance against transient errors; however, it is not entirely resilient. Several resiliency schemes are available to detect and mitigate soft errors in QDI circuits, with approaches based on redundancy proving to be the most effective in ensuring complete resilience across all major QDI implementation paradigms, including NCL, Pre-charge/Weak-charge Half Buffers (PCHB/WCHB), and Sleep Convention Logic (SCL). This research focuses on one such redundancy-based resiliency scheme for QDI NCL circuits, known as the dual-modular redundancy-based NCL (DMR-NCL) architecture, and addresses the absence of formal methods for the verification and analysis of such circuits. A novel methodology has been proposed for formally verifying the correctness of DMR-NCL circuits synthesized from their synchronous counterparts, covering both safety (functional correctness) and liveness (the absence of deadlock). In addition, this research introduces a formal framework for the vulnerability analysis of DMR-NCL circuits against SEU/SEL. To demonstrate the framework’s efficacy and scalability, a prototype computer-aided support tool has been developed, which verifies and analyzes multiple DMR-NCL benchmark circuits of varying sizes and complexities.
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Datta, Mithun, Dipayan Mazumder, Alexander C. Bodoh, and Ashiq A. Sakib. "DMR-SCL: A Design and Verification Framework for Redundancy-Based Resilient Asynchronous Sleep Convention Logic Circuits." Electronics 14, no. 5 (2025): 884. https://doi.org/10.3390/electronics14050884.
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The digital integrated circuit (IC) design industry is continuously evolving. However, the rapid advancements in technology are accompanied by major reliability concerns. Conventional clock-based synchronous designs become exceedingly susceptible to transient errors, caused by radiation rays, power jitters, electromagnetic interferences (EMIs), and/or other noise sources, primarily due to aggressive device and voltage scaling. quasi-delay-insensitive (QDI) asynchronous (clockless) circuits demonstrate inherent robustness against such transient errors, owing to their unique architecture. However, they are not completely immune. This article presents a hardened QDI Sleep Convention Logic (SCL) asynchronous architecture, which can fully recover from radiation-induced single-event effects such as single-event upset (SEU) and single-event latch-up (SEL). Multiple benchmark circuits are designed based on the proposed architecture. The simulation results indicate that the proposed designs offer substantial energy savings per operation, dissipate substantially less power during idle phases, and have lower area footprints in comparison to designs based on an existing resilient Null Convention Logic (NCL) architecture at the cost of increased latency. In addition, a formal verification framework for the proposed architecture is also presented. The performance and scalability of the proposed verification scheme are demonstrated using several multiplier benchmark circuits of varying width.
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Gajewski, Sławomir, Małgorzata Gajewska, and Ryszard J. Katulski. "Trunked Radio Solutions for Special Applications." International Journal of Electronics and Telecommunications 60, no. 4 (2014): 309–14. http://dx.doi.org/10.2478/eletel-2014-0040.
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Abstract In the paper modern concepts of radio communication trunking-dispatch systems for special applications are presented. Basic standards of TETRA, DMR, and cdma2000 are mentioned. The aim of the paper is to present innovative trunking solutions based on the LTE system working both in FDD and TDD mode. The architecture of LTE trunked radio is shown as well as new services possible to implementation are described. The way of TETRA and LTE integration is characterized.
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Pileggi, Silvana, Marta La Vecchia, Elisa Adele Colombo, et al. "Cohesin Mutations Induce Chromatin Conformation Perturbation of the H19/IGF2 Imprinted Region and Gene Expression Dysregulation in Cornelia de Lange Syndrome Cell Lines." Biomolecules 11, no. 11 (2021): 1622. http://dx.doi.org/10.3390/biom11111622.
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Traditionally, Cornelia de Lange Syndrome (CdLS) is considered a cohesinopathy caused by constitutive mutations in cohesin complex genes. Cohesin is a major regulator of chromatin architecture, including the formation of chromatin loops at the imprinted IGF2/H19 domain. We used 3C analysis on lymphoblastoid cells from CdLS patients carrying mutations in NIPBL and SMC1A genes to explore 3D chromatin structure of the IGF2/H19 locus and evaluate the influence of cohesin alterations in chromatin architecture. We also assessed quantitative expression of imprinted loci and WNT pathway genes, together with DMR methylation status of the imprinted genes. A general impairment of chromatin architecture and the emergence of new interactions were found. Moreover, imprinting alterations also involved the expression and methylation levels of imprinted genes, suggesting an association among cohesin genetic defects, chromatin architecture impairment, and imprinting network alteration. The WNT pathway resulted dysregulated: canonical WNT, cell cycle, and WNT signal negative regulation were the most significantly affected subpathways. Among the deregulated pathway nodes, the key node of the frizzled receptors was repressed. Our study provides new evidence that mutations in genes of the cohesin complex have effects on the chromatin architecture and epigenetic stability of genes commonly regulated by high order chromatin structure.
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Iserte, Sergio, Héctor Martínez, Sergio Barrachina, Maribel Castillo, Rafael Mayo, and Antonio J. Peña. "Dynamic reconfiguration of noniterative scientific applications: A case study with HPG aligner." International Journal of High Performance Computing Applications 33, no. 5 (2018): 804–16. http://dx.doi.org/10.1177/1094342018802347.
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Several studies have proved the benefits of job malleability, that is, the capacity of an application to adapt its parallelism to a dynamically changing number of allocated processors. The most remarkable advantages of executing malleable jobs as part of a high performance computer workload are the throughput increase and the more efficient utilization of the underlying resources. Malleability has been mostly applied to iterative applications where all the processes execute the same operations over different sets of data and with a balanced per process load. Unfortunately, not all scientific applications adhere to this process-level malleable job structure. There are scientific applications which are either noniterative or present an irregular per process load distribution. Unlike many other reconfiguration tools, the Dynamic Management of Resources Application Programming Interface (DMR API) provides the necessary flexibility to make malleable these out-of-target applications. In this article, we study the particular case of using the DMR API to generate a malleable version of HPG aligner, a distributed-memory noniterative genomic sequencer featuring an irregular communication pattern among processes. Through this first conversion of an out-of-target application to a malleable job, we both illustrate how the DMR API may be used to convert this type of applications into malleable and test the benefits of this conversion in production clusters. Our experimental results reveal an important reduction of the malleable HPG aligner jobs completion time compared to the original HPG aligner version. Furthermore, HPG aligner malleable workloads achieve a greater throughput than their fixed counterparts.
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Robinson, Eric, Prathamesh M. Kulkarni, Jaya Sarin Pradhan, et al. "Prediction of distant melanoma recurrence from primary tumor digital H&E images using deep learning." Journal of Clinical Oncology 37, no. 15_suppl (2019): 9577. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.9577.
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9577 Background: Patients with resected melanoma are at high risk for systemic recurrence. Quantifying the risk of recurrence can help identify the need for adjuvant immunotherapies, and accelerate the acquisition of survival statistics in clinical trials. Methods: 75 patients with stages I, II, and III melanoma seen at Columbia University Medical Center between 2001 and 2014 and The Icahn School of Medicine at Mount Sinai between 2000 and 2010 were included based on availability of tissue and 24 months of clinical follow-up. Images were scanned into tiff files (Aperio Biosystems). Deep neural net (DNN) architecture was designed consisting of convolutional and recurrent neural networks (CNN, RNN). Using QuPath open source software for nuclear segmentation and cell classification, we generated cell location, density, and clustering features to identify tissue areas for training of network parameters. DNN analyzes image and feature information locally within an H&E image, generating a prediction vote per region, and votes are averaged. Results: The model was validated on two independent external sets of stage I-III primary melanomas. Cohort 1 (Yale Medical Center), had n = 86 patients, of whom 49 were alive or had no evidence of disease at death (no DMR) and 37 died from melanoma. The second set, Cohort 2 (Geisnger Health Systems), had n = 29 patients, 15 without DMR and 14 with DMR. Prediction scores correlated with DMR status in both sets (AUC = 0.94 and 0.77 for Cohorts 1 and 2, respectively). A multivariable Cox proportional hazard model showed DNN recurrence prediction to be an independent prognostic factor for both Cohort 1 (HR = 2.54, 95% CI: 1.54-4.19, p = .0004***) and Cohort 2 (HR = 8.43, 95% CI: 2.58-27.51, p = .001**). Conclusions: We designed a DNN for quantitative prediction of melanoma recurrence from a H&E stained tissue. The prediction score warrants further study in larger patient cohorts and may constitute a novel digital pathology tool for the selection of melanoma patients for adjuvant immunotherapy. [Table: see text]
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Barge, Sonal Arvind, and Gerardine Immaculate Mary. "Improving the reliability of SKINNY-Hash for IoT applications with less area-power overhead." Multidisciplinary Science Journal 7, no. 12 (2025): 2025567. https://doi.org/10.31893/multiscience.2025567.
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The widespread adoption of Internet of Things (IoT) devices has significantly increased the demand for IoT applications, which rely extensively on data collection and network transmission. However, the reliability of these devices, especially regarding the security and privacy of the data they handle, is a significant concern. This issue is further complicated by their exposure to environmental radiation and vulnerability to natural faults and malicious attacks. Cryptographic algorithms are crucial for securing IoT devices, but ensuring their reliability in such challenging environments is difficult. This work introduces a concurrent error detection technique called Space Redundancy with Complement Operands (SRECO) to enhance the reliability of cryptographic algorithms used in IoT devices. The lightweight SKINNY-Hash is adopted for the study. Specifically, SRECO is applied to the SKINNY-128-256 block cipher. Furthermore, we implement a resource-sharing concept to minimize the area-power overhead in the function architecture of SKINNY-Hash caused by the SRECO architecture. The function architecture in SKINNY-Hash is described using Very Large-Scale Integrated Circuits Hardware Description Language (VHDL) and synthesized with the Genus synthesis tool by Cadence, generating area-power reports. ModelSim SE-64 is employed for behavioural verification of the function architecture. The area-power results of our proposed work are compared with the traditional Double Modular Redundancy (DMR) technique, demonstrating that our approach has a low area-power overhead.
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Liu, Qingrui, Changhee Jung, Dongyoon Lee, and Devesh Tiwari. "Compiler-Directed Soft Error Detection and Recovery to Avoid DUE and SDC via Tail-DMR." ACM Transactions on Embedded Computing Systems 16, no. 2 (2017): 1–26. http://dx.doi.org/10.1145/2930667.
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Zhang, Yanting, Jianwei Liu, Zhenyu Guan, Bihe Zhao, Xianglun Leng, and Song Bian. "ARMOR: Differential Model Distribution for Adversarially Robust Federated Learning." Electronics 12, no. 4 (2023): 842. http://dx.doi.org/10.3390/electronics12040842.
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In this work, we formalize the concept of differential model robustness (DMR), a new property for ensuring model security in federated learning (FL) systems. For most conventional FL frameworks, all clients receive the same global model. If there exists a Byzantine client who maliciously generates adversarial samples against the global model, the attack will be immediately transferred to all other benign clients. To address the attack transferability concern and improve the DMR of FL systems, we propose the notion of differential model distribution (DMD) where the server distributes different models to different clients. As a concrete instantiation of DMD, we propose the ARMOR framework utilizing differential adversarial training to prevent a corrupted client from launching white-box adversarial attack against other clients, for the local model received by the corrupted client is different from that of benign clients. Through extensive experiments, we demonstrate that ARMOR can significantly reduce both the attack success rate (ASR) and average adversarial transfer rate (AATR) across different FL settings. For instance, for a 35-client FL system, the ASR and AATR can be reduced by as much as 85% and 80% over the MNIST dataset.
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Korobeynikov, A. V., and M. A. Boyarshinov. "Development of a Bench for Analyzing the Radio Station Operation in the APCO P25, DMR and TETRA Communication Standards Based on Broadband Software-Defined Radios and GNU Radio Software Toolkit." Vestnik IzhGTU imeni M.T. Kalashnikova 25, no. 4 (2022): 73–85. http://dx.doi.org/10.22213/2413-1172-2022-4-73-85.
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The article discusses the development of an instrument complex (bench, stand) for the study of digital radio communication standards: APCO P25, DMR and TETRA, based on software-defined radio systems (SDR) technologies in voice mode. The bench is based on the HackRF One broadband SDR transceiver and the GNU Radio open software toolkit. Along with the SDR transceiver HackRF One, it is proposed to use the SDR TV tuner AstroMeta Digital TV Dongle as an available receiver. The structure of the hardware and software parts of the bench is proposed. The software implementation of listed digital radio communication standards is based on the open libraries of the Osmocom project: the BoadBot OP25 and TETRA Live Monitor libraries. The operating system Linux Debian 10 and the software toolkit GNU Radio 3.7 were used for practical testing of the bench functioning. The practical testing results of the developed bench are presented both when interacting in voice mode with radio stations of the specified radio communication standards, and between the SDR transmitter HackRF One and the SDR TV tuner AstroMeta Digital TV Dongle. For the radio communication standards APCO P25 and DMR, the receiving and transmission modes of the speech signal have been practically tested on the developed bench, and for the radio communication standard TETRA, the modes of scanning the radio broadcast and receiving the speech signal have been tested. As a bench operability confirmation for the listed radio communication standards, the screenshots of programs implementing the specified modes of interaction between the bench hardware components are given. The proposed bench architecture allows to expand the list of supported radio standards. The developed bench can be used: 1) for educational purposes in the study of radio communication standards; 2) in the development and debugging of radio communication systems under development; 3) for control testing during the release of radio systems.
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Hasegawa, Shiho. "A study of the biological concept in architectural thought: A comparison between 'Der raum als membran' (1926) and 'Metabolism' (1960)." SAJ - Serbian Architectural Journal 11, no. 3 (2019): 427–40. http://dx.doi.org/10.5937/saj1903427h.
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This study analyzes the biological influence on the architecture in the 20th century by focusing on two particular biological architectural thought; "Der Raum als Membran (Space as Membrane)" by Siegfried Ebeling in 1926 and "Metabolism" by a group of Japanese architects in 1960. First, I discuss "Der Raum als Membran". Ebeling saw architecture or space as a biological membrane, like skin or a cell, and he proposed a theory of biological architecture. He not only introduced into planning an environment this biological metaphor with its flexibility of a membrane but also incorporated a biological concept like Umwelt. Second, I investigate a manifesto by the name of "Metabolism", which was produced in 1960 by a group of Japanese architects. They thought buildings and urban designs had an existence and underwent metabolism, which is a basic function of living things, and proposed variable and proliferate architectures having dynamic time spans. By comparing these biological architectural concepts, I point out three main similarities: 1) the expansion of the biological concept into architecture; 2) the cell as a metaphor; and 3) dynamic buildings or urban design. Although the authors had different backgrounds, all of them introduced new architectural ideas in their own times.
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Iserte, Sergio, Rafael Mayo, Enrique S. Quintana-Ortí, Vicenç Beltran, and Antonio J. Peña. "DMR API: Improving cluster productivity by turning applications into malleable." Parallel Computing 78 (October 2018): 54–66. http://dx.doi.org/10.1016/j.parco.2018.07.006.
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Preethi Veerlapalli. "ROISegNet: A Region-Focused Deep Learning Framework for Precision-Driven Medical Image Segmentation." Journal of Information Systems Engineering and Management 10, no. 21s (2025): 243–61. https://doi.org/10.52783/jisem.v10i21s.3311.
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Breast cancer is still one of the leading causes of death in women globally. Breast thermography is a non-invasive imaging procedure that can be used as an early screening device to identify temperature irregularities that suggest breast malignancies can develop. Early diagnosis is key to achieving better treatment and survival outcomes. Automated methods for breast cancer detection have drawn much attention due to the proliferation of artificial intelligence (AI) and deep learning (DL). This paper presents a new deep learning model, ROISegNet, that enables accurate segmentation of the region of interest (ROI) from breast thermography images. Our method utilizes semantic segmentation approaches using an atrous convolution-based deep learning architecture that effectively extracts the area of interest (ROI) where the abnormality is present in the human body, which potentially helps in early diagnosis. ROISegNet employs an advanced decoder module in addition to Intelligent Segmentation of Breast ROI (ISBROI), thereby achieving high segmentation accuracy. Evaluation on a benchmark dataset called DMR-IR shows that compared to other state-of-the-art backbones networks like Atrous Convolution, VGG19, ResNet50, and InceptionV3, the model's peak accuracy is 98 63%.
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Gi, Weng-Tein, Jan Haas, Farbod Sedaghat-Hamedani, et al. "Epigenetic Regulation of Alternative mRNA Splicing in Dilated Cardiomyopathy." Journal of Clinical Medicine 9, no. 5 (2020): 1499. http://dx.doi.org/10.3390/jcm9051499.
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In recent years, the genetic architecture of dilated cardiomyopathy (DCM) has been more thoroughly elucidated. However, there is still insufficient knowledge on the modifiers and regulatory principles that lead to the failure of myocardial function. The current study investigates the association of epigenome-wide DNA methylation and alternative splicing, both of which are important regulatory principles in DCM. We analyzed screening and replication cohorts of cases and controls and identified distinct transcriptomic patterns in the myocardium that differ significantly, and we identified a strong association of intronic DNA methylation and flanking exons usage (p < 2 × 10−16). By combining differential exon usage (DEU) and differential methylation regions (DMR), we found a significant change of regulation in important sarcomeric and other DCM-associated pathways. Interestingly, inverse regulation of Titin antisense non-coding RNA transcript splicing and DNA methylation of a locus reciprocal to TTN substantiate these findings and indicate an additional role for non-protein-coding transcripts. In summary, this study highlights for the first time the close interrelationship between genetic imprinting by DNA methylation and the transport of this epigenetic information towards the dynamic mRNA splicing landscape. This expands our knowledge of the genome–environment interaction in DCM besides simple gene expression regulation.
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Xiaohui, Wei, Wang Chenyang, Wu Qi, Yu Hongmin, and Yue Hengshan. "Systolic array-based CNN accelerator soft error approximate fault tolerance design." Scientific Insights and Discoveries Review 6 (October 14, 2024): 256–67. http://dx.doi.org/10.59782/sidr.v6i1.192.
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To satisfy the massive computational requirement of Convolutional Neural Networks, various Domain-Specific Architecture based accelerators have been deployed in large-scale systems. While improving the performance significantly, the high integration of the accelerator makes it much more susceptible to soft-error, which will be propagated and amplified layer by layer during the execution of CNN, finally disturbing the decision of CNN and leading to catastrophic consequences. CNNs have been increasingly deployed in security-critical areas, requiring more attention to reliable execution. Although the classical fault-tolerant approaches are error-effective, the performance/energy overheads introduced are non-negligible, which is the opposite of CNN accelerator design philosophy. In this article, we leverage CNN's intrinsic tolerance for minor errors and the similarity of filters within a layer to explore the Approximate Fault Tolerance opportunities for CNN accelerator fault tolerance overhead reduction. By gathering the filters into several check groups by clustering to perform an inexact check while ensuring that serious errors are mitigated, our approximate fault tolerance design can reduce fault tolerance overhead significantly. Furthermore, we remap the filters to match the checking process and the dataflow of systolic array, which can satisfy the real-time checking demands of CNN. Experimental results exhibit that our approach can reduce 73.39%performance degradation of baseline DMR.
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Alaryani, Fatima S. "Examining the pancreatic regenerative potential of Nigella sativa in diabetic rats: Evaluation of histological changes and transcription factors pdx-1 and neurog-3 levels." Materials Express 14, no. 3 (2024): 376–84. http://dx.doi.org/10.1166/mex.2024.2685.
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Pancreatic β cell neogenesis and proliferation represent promising avenues for diabetes management. Nigella sativa, known for its potent anti-inflammatory and antioxidant properties, has demonstrated efficacy in promoting regeneration across various organ systems. This study investigates the potential of Nigella sativa in pancreatic regeneration by examining pancreatic histology in addition, the expression levels of the key transcription factors, comprising NEUROG-3, PDX-1, INS-1, and INS-2. Twenty-four rats were categorized in 4sets that is negative control, positive control, normal, and treatment. Diabetes was prompted through intraperitoneal administration of alloxan hydrate. After 21 days of diabetes induction, the treatment set was applied with N. sativa extract, the positive control set was administered Glibenclamide, while the negative control group received no treatment. Parameters such as biochemical markers, oxidative stress markers, pancreatic islet architecture changes, and the expression levels of the NEUROG-3, PDX-1, INS-1, and INS-2 were assessed. Data analysis, conducted through DMR Test and ANOVA with a 5% threshold of significance, revealed significant insights into the consequence of N. sativa on the parameters under investigation. The results propose a possible part for N. sativa in promoting pancreatic regeneration and warrant further exploration for its application in diabetes management.
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Chugulu, Godfrey. "Hybrid Communication Architecture Based on Hierarchical Computing for Low Voltage Power Network Automation in Developing Countries." Journal of ICT Systems 2, no. 2 (2024): 81–106. https://doi.org/10.56279/jicts.v2i2.122.
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Utility companies in developing countries, such as Tanzania, have made significant advancements in automating the generation, transmission, and primary distribution segments of their electrical grids. However, automation in the Low Voltage Power Network (LVPN) remains minimal and largely unmonitored, leading to manual fault management that results in losses and inconveniences for both utilities and customers. Effective Smart Grid (SG) infrastructure relies on seamless communication between end-devices and controlling systems to ensure timely execution of critical applications. Key SG applications for LVPN automation include Advanced Metering Infrastructure (AMI), Distributed Energy Resource (DER) coordination, and Distribution Automation (DA), each with specific latency requirements that must be met. Current architectures outlined in the literature present challenges for utility companies attempting to implement these applications while satisfying latency criteria for automation. This paper introduces a hybrid communication architecture based on a three-level hierarchical computing model specifically designed for LVPN automation. Laboratory results indicate that this architecture achieves an average delay of 7.059ms, significantly below the maximum allowable latency of 20ms for AMI, DER, and DA which demonstrates the architecture's capability for effective LVPN automation.
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O Baror, Stacey, Richard Adeyemi, I, and Hein S. Venter. "Functional Architectural Design of a Digital Forensic Readiness Cybercrime Language as a Service." European Conference on Cyber Warfare and Security 22, no. 1 (2023): 73–82. http://dx.doi.org/10.34190/eccws.22.1.1240.
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Developing a generic digital forensic solution in a cloud computing platform that can address the functional requirements of digital forensic stakeholders is a complex process. The solution would require a technology-independent architectural design that addresses the challenges of incident threat identification, triggering, incident threat isolation and investigation. Existing approaches are limited to the functionality that treats these four challenges individually without the due diligence to consider their interoperability. This study proposes a context-independent and technology-neutral architecture to address these issues by developing a digital forensic readiness (DFR) based on a human language communication interaction (HLI) system that could create a cybercrime language as a service (DFClaaS). The functional architectural design of the proposed DFR HLI DFClaaS system comprises microservices, layered and event/component-based architectural patterns on top of cloud architectural patterns. The DFR HLI DFClaaS system integrates flexibility and other quality requirements to separate concerns while accommodating rigid requirements like security and reliability. The developed architecture is essential for any human-centred digital forensic solution. Therefore, integrating the developed architecture presents a reliable baseline for the digital forensic community.
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Tragbar, Klaus. "Heinrich Klotz und die architectura – und was in 50 Jahren aus ihr wurde." architectura 50, no. 1-2 (2022): 10–23. http://dx.doi.org/10.1515/atc-2020-1004.
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Abstract In 1971, Heinrich Klotz, who had returned from a stay as a visiting professor at Yale University in New Haven, Connecticut, founded architectura. Zeitschrift für Geschichte der Baukunst/Journal of the History of Architecture with the financial support of the Deutsche Forschungsgemeinschaft (DFG). Klotz experiments with different formats of essays but retires as editor in 1976. Under subsequent editors, architectura continues to develop into the leading journal for the history of architecture, whose essays are not subject to any temporal or local limitations and reflect the entire breadth of research in the history of architecture.
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Idoko, Ikenna Emmanuel, Onyeka Emmanuel Uzowulu, and Ikenna Michael Onuorah. "Minimalist Architecture and the Concept of Less is More: The Place of Hellenistic Cynicism in the Architectural Concept of Mies Van Der Rohe." International Journal of Research and Innovation in Social Science VIII, no. II (2024): 211–24. http://dx.doi.org/10.47772/ijriss.2024.802015.
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Historically, cynicism as a philosophical movement started and soared in the Hellenistic period. Disquisition on cynicism concerning architecture and architectural philosophy has been relatively neglected. This article addresses cynicism, delving into the philosophy of the cynics’ lifestyle and beliefs vis-à-vis less is more (minimalism), which was an epigram adopted by Mies Van Der Rohe in his architectural designs and buildings. Standing on the shoulder of simplicity, as the common denominator between cynicism and minimalism, the authors create an intercourse between philosophy and architecture through the appraisal of the philosophy of the Cynics and the architectural works of Mies Van Der Rohe. This further buttresses the innate need for continual interdisciplinary research works to unearth and expound more interesting synergy in human architectural and philosophical experiences.
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Fernández, Lisardo, Ricardo Olanda, Mariano Pérez, and Juan M. Orduña. "A Web-Based Tool for Automatic Detection and Visualization of DNA Differentially Methylated Regions." Electronics 10, no. 9 (2021): 1083. http://dx.doi.org/10.3390/electronics10091083.
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The study of Deoxyribonucleic Acid (DNA) methylation has allowed important advances in the understanding of genetic diseases related to abnormal cell behavior. DNA methylation analysis tools have become especially relevant in recent years. However, these tools have a high computational cost and some of them require the configuration of specific hardware and software, extending the time for research and diagnosis. In previous works, we proposed some tools for DNA methylation analysis and a new tool, called HPG-DHunter, for the detection and visualization of Differentially Methylated Regions (DMRs). Even though this tool offers a user-friendly interface, its installation and maintenance requires the information technology knowledge specified above. In this paper, we propose our tool as a web-based application, which allows biomedical researchers the use of a powerful tool for methylation analysis, even for those not specialized in the management of Graphics Processing Units (GPUs) and their related software. The performance evaluation results show that this web-based version of HPG-DHunter tool improves the response time offered to the user, also offering an improved interface and higher visualization quality, while showing the same efficiency in DMR identification than the standalone version.
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TURKI, Wouroud, and Amine HADJ TAIEB. "The Integration of Troglodyte Architecture into Contemporary Architecture, A Fusion of Tradition and Modernity: The Case of Dar Hi in Nefta." Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA 7, no. 1 (2024): 972–78. http://dx.doi.org/10.38027/iccaua2024en0069.
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Troglodyte architecture, characterized by the utilization of natural caves or structures carved into rock, stands as amesmerizing testament to humanity's adaptability to its surroundings. This study explores the integration of troglodytearchitecture into contemporary design, with a specific focus on Dar Hi in Nefta, Tunisia. It investigates the historicalfoundations, core principles, and the application of troglodyte architecture in modern architectural practices. Theanalysis begins with a historical overview, tracing the evolution of troglodyte structures and their adaptability todiverse environments. The centerpiece of this exploration is the detailed examination of Dar Hi, showcasing how itencapsulates traditional troglodyte elements within a contemporary architectural framework. It dissects thearchitectural components, materials, and design strategies employed, emphasizing sustainability and culturalpreservation. Moreover, this research highlights the experiential aspect, emphasizing how Dar Hi's design fosters asensory connection with Nefta's cultural heritage. It emphasizes how the integration of troglodyte architecturalelements within the establishment creates a unique blend of tradition and modernity. By spotlighting the case studyof Dar Hi, this study sheds light on the potential of harmonizing ancient architectural wisdom with modern design,aiming to inspire discussions on preserving and creatively incorporating troglodyte architecture into contemporaryarchitectural discourse.
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Park, Hyun A. "A study on the geometric spatial characteristics in Mies van der Rohe's architectural design." Korea Institute of Design Research Society 10, no. 2 (2025): 486–96. https://doi.org/10.46248/kidrs.2025.2.486.
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This paper derives geometric space characteristics based on geometric space and Mies van der Rohe's architectural design, and analyzes how such space appears in Mies van der Rohe's architecture. The purpose is to analyze geometric space characteristics in architecture and derive the results by focusing on representative early buildings after C.I.A.M. (International Competition for Modern Architecture). This study analyzes cases based on Mies van der Rohe's buildings that changed after C.I.A.M. The analysis criteria were derived through geometric pure figures, and analyzed with three geometric space characteristics: symbolic, relational, and hierarchical. As a result, the geometric symbol of space was mainly expressed through the derivation of geometric pure figures and the repetitive forms of figures, and the repetitive and simple forms further emphasize the symbolic space. The geometric relationship of space is mainly expressed as a flowing connection in the horizontal plane space of architecture, and the connection of space is developed and expressed as the flow of moving lines. The geometric hierarchy of space is mainly expressed through the vertical separation of space, and the separation of space is centered on the vertical core, and the serial space is expressed through the hierarchical arrangement. These spatial characteristics are expressed through geometric pure shapes and become the basis for planning essential space. Finding such essential space and maintaining formal originality also plays an important role in the development of future architectural forms. Therefore, starting with this study, we aim to find the essence of architectural space.
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Sean, Keller. "Architecture after Drafting." Zeitschrift für Medien- und Kulturforschung 3, no. 1 (2012): 119–34. http://dx.doi.org/10.28937/1000106359.
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"In den letzten zwei Jahrzehnten wurde die Dominanz des Zeichnens für die Architektur von einer ganzen Reihe von digitalen Repräsentationstechniken verdrängt. Der Beitrag stellt eine kritische Antwort auf Mario Carpos These dar, dieser Wandel bringe Architektur zu einer »autographischen« Praxis zurück, die noch vor die Renaissance zurückreiche. Demgegenüber argumentiert der Beitrag, dass Architektur nach dem Modell von Rosalind Kraus als post-medium art (»postmediale Kunst«) gedacht werden sollte. </br></br>Over the last two decades drawing has been displaced from its dominant role in architecture by a range of computational representations. This article offers a critical response to Mario Carpo's recent argument that this shift returns architecture to an 〉autographic〈 mode of practice not seen since before the Renaissance. In contrast, I suggest that architecture today should be thought of through Rosalind Krauss's model of a post-medium art. "
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Allen, Giancarlo. "ConstructiveAlps. Contemporaneità, sostenibilità, regionalità / ConstructiveAlps. Contemporaneity, sustainability, regionality." Regionalità e produzione architettonica contemporanea nelle Alpi, no. 1 ns, november 2018 (November 15, 2018): 194–201. http://dx.doi.org/10.30682/aa1801u.
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ConstructiveAlps, an award that takes on the thought of Mies Van der Rohe who says «True architecture is always objective and is the expression of the inner structure of our time»; not therefore an Alpine Architecture award but an award for sustainable architecture in the Alps that recognizes the responsibility of Architecture in the effects of climate change. So “constructive” means useful, effective, concrete. 1300 architectures in 4 editions judged by holistic criteria considering energy efficiency, appropriate technologies, use of local and coherent materials, embodied energy, life cycles, sobriety, restraint, impact on the landscape, soil consumption and healthiness, life’s quality, building costs and public transport. The winning projects are absolutely necessary architectures, multifunctional, wooden, with very high energy performances but also social and cultural, able to encourage the communities maintenance in the alpine territories, are civil architecture able to have physical and figurative centrality, to be a reference for the rebirth of places with abandonment risk. Making sustainable architecture facilitate new regionality with a glocal attitude that enhance cultural differences.
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Ahmet, Hadrovic. "THE HISTORICAL MUNICH CITY IN GERMANY." ISRG Journal of Arts Humanities & Social Sciences (ISRGJAHSS) II, no. IV (2024): 111–38. https://doi.org/10.5281/zenodo.12743713.
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<em>The author's trips to Germany were mostly of a study nature, and some of them were just trips to other European cities (Amsterdam, Nice and Oslo). The study trips (1999, 2007 and 2011) were related to a visit to the famous trade fair (the world's leading one of its kind) for architecture, materials and systems (BAU Munich), which takes place every two years in Munich. Visits to this fair were of great importance for the Author, since (at the end of the 20th and beginning of the 21st centuries) he was intensively engaged in architectural design, and since 1989 at the Faculty of Architecture in Sarajevo he taught subjects that by their nature followed contemporary trends in architecture (Architectural physics, Structural systems in architecture, Detailed materialization of envelopes of architectural objects, New approach to conceptualization and materialization of architecturally defined space, Architecture as an energy system...). As the fair was held for four days (it was held in mid-January), the author used the opportunity to get to know the architecture of Munich on the spot, as well as its architectural cultural and historical heritage (Maximilianeum, Prinzregentenstraß, Ludwigstraße, Marienplatz, Alte Pinakothek, Bayerisches Nationalmuseum, Neues Rathaus, Nationaltheater, Glyptotheka ...) as well as contemporary architecture. In particular detail, the Author visited the Olympic Park in Munich (Der Olympiapark in München), BMW Hochhaus and BMW Welt, Allianz Arena...</em>
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Colombo, Gabriel Miller. "A House for the Spirit." Religion and the Arts 27, no. 4 (2023): 498–517. http://dx.doi.org/10.1163/15685292-02704003.
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Abstract This paper highlights the architectural theory and practice of the twentieth-century Dutch Benedictine monk and architect Dom Hans van der Laan as a lens through which to view architecture and urbanism’s underlying spiritual purpose. Van der Laan’s theologically grounded vision of architecture as a sacramental mediator between the human, the natural, and the divine and empirically based rubric by which to achieve that end—through human-centric proportion, polyrhythm, and humble materiality—provide a robust framework for crafting cities and homes that reveal the sacredness inherent in the world. Through an analysis of Van der Laan’s theory and an examination of his exemplary Roosenberg Abbey, the paper illuminates the spatial, sensory, and dimensional qualities currently lacking in many contemporary urban and architectural spaces and presents a set of strategies for adapting them to better support human flourishing.
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Liu, Dingqian, and Jiwei Liu. "VoxelMorph++: a convolutional neural network architecture for unsupervised CBCT to CT deformable image registration." ITM Web of Conferences 47 (2022): 02014. http://dx.doi.org/10.1051/itmconf/20224702014.
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We use an unsupervised method based on the VoxelMorph architecture for Cone-beam computed tomography (CBCT) to CT deformable image registration (DIR), and propose VoxelMorph++, a new architecture for predicting the deformation vector field (DVF). The proposed architecture (1) overcomes the limitation that the optimal depth of encoder-decoder is unknown, by forming a nested structure where each feature with varying depth in the encoder path has a corresponding depth decoder; (2) fuses features of varying semantic scales more flexibly by redesigning skip connections. In the testing phase, we used ITK-SNAP software to semi-automatically segment the patients’ lung regions as labels to solve the problem of expensive manual labelling. We evaluated these two architectures using lung region registration results from 10 patients’ CBCT and CT images. After registration, the mean Dice score improved from 0.8556 to 0.9412 and 0.9430 for VoxelMorph and the proposed architecture, respectively. The results show that both architectures perform well in our dataset and the proposed architecture outperforms VoxelMorph in terms of registration accuracy.
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Wu, Xinghua, Mingzhe Wang, Jinsheng Shen, and Yanwei Gong. "Towards Double-Layer Dynamic Heterogeneous Redundancy Architecture for Reliable Railway Passenger Service System." Electronics 13, no. 18 (2024): 3592. http://dx.doi.org/10.3390/electronics13183592.
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Researchers have proposed the dynamic heterogeneous redundancy (DHR) architecture, which integrates dynamic, heterogeneous, redundant, and closed-loop feedback elements into the system, to fortify the reliability of the railway passenger service system (RPSS). However, there are at least two weaknesses with the common DHR architectures: (1) they need system nodes with enough computing and storage resources; (2) they have hardly considered the reliability of DHR architecture. To this end, this paper proposes a double-layer DHR (DDHR) architecture to ensure the reliability of RPSS. This architecture introduces a set of algorithms, which are optimized co-computation and ruling weight optimization algorithms for the data processing flow of the DDHR architecture. This set improves the reliability of the DDHR architecture. For the evaluation of the reliability of DDHR architecture, this paper also proposes two metrics: (1) Dynamic available similarity metric. This metric does not rely on the overall similarity of the double-layer redundant executor sets but evaluates the similarity of their performance under the specified interaction paths within a single scheduling cycle. The smaller its similarity, the higher its reliability. (2) Scheduling cycle under dual-layer similarity threshold. This metric evaluates the reliability of the RPSS under actual conditions by setting the schedulable similarity thresholds between the same and different layers of the dual-layer redundant executives in the scheduling process. Finally, analog simulation experiments and prototype system building experiments are carried out, whose numerical experimental results show that the DDHR architecture outperforms the traditional DHR architecture in terms of reliability and performance under different redundancy and dynamically available similarity thresholds, while the algorithmic complexity and multi-tasking concurrency performance are slightly weaker than that of the DHR architecture, but can be applied to the main operations of the RPSS in general.
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Khan, Saif ur Rehman, Asif Raza, Muhammad Tanveer Meeran, and Umair Bilhaj. "Enhancing Breast Cancer Detection through Thermal Imaging and Customized 2D CNN Classifiers." VFAST Transactions on Software Engineering 11, no. 4 (2023): 80–92. http://dx.doi.org/10.21015/vtse.v11i4.1684.
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Breast cancer is one of the most prevalent and life-threatening forms of cancer due to its aggressive nature and high mortality rates. Early detection significantly improves a patient's chances of survival. Currently, mammography is the preferred diagnostic method, but it has drawbacks such as radiation exposure and high costs. In response to these challenges, thermography has become a less invasive and cost-effective alternative, gaining popularity. We aim to develop a cutting-edge model for breast cancer detection based on thermal imaging. The initial phase involves creating a customized machine-learning (ML) model built on convolutional neural networks (CNN). Subsequently, this model undergoes training using a diverse dataset of thermal images depicting breast abnormalities, enabling it to identify breast cancer effectively. This innovative approach promises to revolutionize breast cancer diagnosis and offers a safer and more accessible alternative to traditional methods. In our recent study, we leveraged thermal image processing techniques to forecast breast cancer precisely based on its external manifestations, particularly in cases where multiple factors are interconnected. This research employed various image classification methods to categorize breast cancer effectively. Our comprehensive approach encompassed segmentation, texture-based feature extraction from thermal images, and subsequent image classification, leading to the successful detection of malignant images. Our study harnessed the power of machine learning to create a tailored classifier, merging key components from GoogleNet, including the utilization of 2D CNNs and activation functions, with the ResNet architecture. This hybrid approach incorporated batch normalization layers following each convolutional layer and employed max-pooling to enhance classification accuracy. Next, we used a sample dataset of carefully selected images from DMR-IR to train our proposed model. The outcomes of this training demonstrated significant improvement over existing methods, with our suggested 2D CNN classifiers achieving an impressive classification rate of 95%, surpassing both the SVM and current CNN models, which achieved rates of 91% and 71%, respectively.
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Kashiwagi, Nobuo, Tomoko Hyodo, Kazunari Ishi, et al. "Spontaneously infarcted parotid tumours: MRI findings." Dentomaxillofacial Radiology 48, no. 5 (2019): 20180382. http://dx.doi.org/10.1259/dmfr.20180382.
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Objectives: To report MRI findings of spontaneous infarction in parotid tumours. Methods: 14 patients (13 male, 1 female; mean age 73 years) with spontaneously infarcted parotid tumours were reviewed retrospectively. MR images were assessed for the location, the presence of synchronous parotid masses, margin characteristics, signal intensity on T 1 and T 2 weighted images, and internal architecture according to the distribution of T 2 signal hyperintensity. Results: 12 tumours were located in the parotid tail and 2 in the superficial lobe. Synchronous parotid masses were seen in four tumours, three of which were located in the ipsilateral parotid tail and one in the contralateral parotid tail. Seven tumours had well-defined margins and seven had ill-defined margins. The signal intensities on T 1 weighted images were a mixture of high and intermediate in all cases; in 11 tumours, hyperintense areas were dominant. On T 2 weighted images, all tumours also showed a mixture of high and intermediate signal intensities. Internal architectures on T 2 weighted images were mosaic hyperintensity in three tumours, central hyperintensity in five, and multiseparated hyperintensity in six. Conclusions: Spontaneously infarcted parotid tumours were mostly located in the parotid tail and showed mixed signal intensities with predominant hyperintensity on T 1 weighted images. Half of the tumours had ill-defined margins, and the internal architectures varied.
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M, Lakshmi Kiran, Nikhileswar K, and Venkata Ramanaiah K. "FPGA IMPLEMENTATION OF CSD BASED NN IMAGE COMPRESSION ARCHITECTURE." ICTACT Journal on Microelectronics 6, no. 4 (2021): 1052–55. https://doi.org/10.21917/ijme.2021.0183.
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Complexity will be the critical issue in VLSI implementation of Image Compression Architectures. Especially it will be predominant issue while dealing with NN based image compression architectures. Due to the development of FPGA, dealing of NN Image Compression Architecture becomes smoother. Furthermore reducing power consumption of those architectures can be deal with CSD algorithms. NN based compression can be added to standard JPEG compression is proved be an efficient strategy for dealing images of high resolution in terms of speed and power. CSD algorithm is proved to provide low power consumption along with low computation time while dealing NN structures. The proposed architecture is hence based on CSD Floating Point Matrix Multiplier (FPMM) and it is synthesized and implemented using Xilinx Vivado Artix7 and Nexys DDR boards. Simulation with MATLAB & Xilinx Vivado is carried out for this work and almost same results are observed.
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Lizondo Sevilla, Laura, José Santatecla Fayos, and Nuria Salvador Luján. "Mies en Bruselas 1934. Síntesis de una arquitectura expositiva no construida." VLC arquitectura. Research Journal 3, no. 1 (2016): 29. http://dx.doi.org/10.4995/vlc.2016.4142.
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<p>The article delves into the complex world of exhibition architectures, those whose destiny is reduced to be mounted, exposed and dismantled in a short period of time. A process that allows a quick experience of architecture, bounded in time, and whose experimentation gives rise to the birth of new concepts. The text focuses on the German Pavilion designed by Mies van der Rohe for the Brussels World’s Fair of 1934, his only unbuilt ephemeral architecture due to the political uniqueness of the moment. Now, criticism and the archive allow us to reinterpret its contribution to the history of architecture.</p>
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Hanenberg, Norbert, Daniel Lohmann, and Christian Raabe. "The Heritage of Mies." Heritage of Mies, no. 56 (2017): 4–5. http://dx.doi.org/10.52200/56.a.kb7t9i2r.
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Mies van der Rohe’s built work covers a timeframe of over 60 years, including two world wars and several revolutionary events in the history of architecture. The extraordinary architect has influenced 20th century architecture worldwide like few others have. In the context of several restoration projects, the time has come to review the condition of his buildings: Is their materiality as timeless as their appearance? Did his constructions, which are of sometimes an experimental nature, prove to be sustainable, or did they fall into disrepair? How can Mies van der Rohe buildings be documented, repaired, restored, reconstructed, without losing the characteristic details of his work, and in order to preserve the architectural integrity and relevance of the Mies van der Rohe's oeuvre?
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Munaf, S., Dr A. Bharathi, and Dr A. N. Jayanthi. "Double Pumping Low Power Technique for Coarse - Grained Reconfigurable Architecture." International Journal of Electrical and Electronics Research 4, no. 1 (2016): 10–15. http://dx.doi.org/10.37391/ijeer.040103.
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Coarse-grained reconfigurable architectures (CGRAs) require many processing elements (PEs) and a con- figuration memory unit (configuration cache) for reconfiguration of its PE array. Though this architecture is meant for high performance and flexibility. Power reduction is very crucial for CGRA to be more competitive and reliable processing core in embedded systems. We propose a DDR SDRAM (Double Data Rate Synchronous Dynamic Random Access Memory) architecture to reduce power-overhead caused by reconfiguration. The power reduction can be achieved by using the characteristics like double pumping the data bus and an I/O buffer between the memory and the data bus of DDR SDRAM. All modules have been designed at behavioral level with VHDL coding and to Simulate in Xilinx ISE navigator.
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Buggert, Daniel, and Anke Naujokat. "Architekturgeschichte der ›Aachener Schule‹." architectura 50, no. 1-2 (2022): 40–49. http://dx.doi.org/10.1515/atc-2020-1008.
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Abstract The ›Aachen School‹ of architectural history analyzes and interprets built structures with the holistic perspective of a trained architect. The first step is a very detailed investigation of the building, using the methods of Historical Building Research. At the same time, archival sources and structural considerations help to develop a clearer picture of a building’s original design concept and its development during the process of planning and realization. Based on this preparatory research, the focus is broadened, applying methods and discussing topics from the perspective of art history and architectural theory and integrating, if necessary, further interdisciplinary collaboration. The overarching premise is that architecture, beyond its time-bound historical condition, is also determined by essential timeless or metahistorical characteristics. These form an important level of knowledge for architectural historians as well as for architects. Architectural history, thus, is not a mere historical science, but also makes an important contribution to the general architectural discourse.
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Borsari, Andrea. "Georg Simmel und die Ästhetische Theorie der Architektur." Simmel Studies 28, no. 1 (2024): 9–42. https://doi.org/10.7202/1115153ar.
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The article is dedicated to the reconstruction and recapitulation of Georg Simmel's relationship to architecture and to the aesthetics of the field of architecture. To this aim, a number of texts have been identified and discussed in Simmel's production that describe the urban dimension, as dimension of the city and of architecture as a modality of the construction of buildings, objects and places to inhabit the world and thus give it a certain configuration. From this discussion derives the plural field of oppositions in relation to the urban-architectural dimension, according to a view of Simmelian thought based on a kind of law of contrast, which can be exemplified in the following set of “oppositional pairs” found in Simmel's work: nature and culture (§ 2), hyperaesthesia and anaesthesia (§ 3), aesthetic “superadditum” and abstraction (§ 4), artistic will and practical functionality (§ 5), connecting and separating (§ 6), transience and eternity or, in architectural terms, temporary and solidity (§ 7), freedom and solitude - subjective culture and objective culture (§ 8). The paper proposes an attempt to trace this series of contrasts and to conclude with an initial assessment of the path traveled and some reflections on a possible convergence between aesthetic and social morphology (§ 9).
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Skibiński, Franciszek. "The Gdańsk Builder Bartel Ranisch (1648–1710?): New Research on His Biography and Architectural Activity." Biuletyn Historii Sztuki 87, no. 1 (2025): 5–34. https://doi.org/10.36744/bhs.2553.
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This essay presents the builder Bartel Ranisch, who is the author of one of the most exceptional books on architecture to appear in Europe in the 17th century. Titled Beschreibung Aller Kirchen-Gebäude der Stadt Dantzig and published in 1695, it was an illustrated description of Gdańsk’s churches. According to the author, it aimed to reestablish the skills needed to build complex architectural structures, particularly rib vaults, in order to stimulate the development of architecture in the city. The aim of this essay is to analyse Ranisch’s work and contextualise his biography by describing his background, education and position in the local architectural milieu. This approach will allow for a better understanding of the context in which his book was written. Furthermore, it will provide a better understanding of the Gdańsk architectural milieu in the second half of the 17th and early 18th centuries, which has so far remained largely removed from the interest of researchers.
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Wu, Yichen. "Facade and Envelope Design in Architecture--The Evolution, Technological Innovation, and Visual Expression." Communications in Humanities Research 45, no. 1 (2024): 1–8. http://dx.doi.org/10.54254/2753-7064/45/20240071.
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This essay explores the evolution, technological innovation, and visual expression of facades and envelopes in modern architecture through the lens of three seminal case studies: Notre Dame Cathedral in Paris, Mies van der Rohe's Farnsworth House, and Walter Gropius's Bauhaus School. These case studies highlight the transformative impact of architectural design principles on building aesthetics and functionality. The Notre Dame Cathedral introduced a revolutionary structural system that liberated the facade from its traditional load-bearing role, allowing for expansive stained-glass windows and intricate stone carvings that set the stage for future architectural innovations. Mies van der Rohe's Farnsworth House exemplifies the minimalist approach, emphasizing transparency and the seamless integration of interior and exterior spaces. The Bauhaus School, under Gropius's leadership, merged art, technology, and craftsmanship, creating a new architectural language characterized by simplicity and functional beauty. Through a detailed analysis of these projects, the essay provides insights into the enduring influence of these architectural milestones on contemporary design practices.
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Schuh, Günther, Alexander Keuper, Frederike Hellwig, and Christina Ruschitzka. "Kreislauforientierte Produktarchitekturen/Designing cycle-orientated product architecture – Methodology for designing product architectures for the circular economy across obsolescence cycles." wt Werkstattstechnik online 115, no. 01-02 (2025): 34–41. https://doi.org/10.37544/1436-4980-2025-01-02-38.
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Um den Herausforderungen des Klimawandels und der Ressourcenknappheit zu begegnen, müssen Konzepte der Kreislaufwirtschaft für neue Produkte etabliert werden. Bestehende Produktarchitekturen erschweren eine zirkuläre Wertschöpfung, weshalb neue Konzepte zur Gestaltung und Modularisierung nötig sind. Dieser Beitrag bewertet Ansätze zur Schaffung zirkulärer Produkte und entwickelt darauf aufbauend eine Methodik für die Modularisierung von Produktarchitekturen, wobei Obsoleszenz und R-Strategien berücksichtigt werden.
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Malewczyk, Michał, and Piotr Czyż. "Features of irregularity in examples of Polish multi-family architecture constructed in 2011–2021 and nominated for the Mies van der Rohe award." Technical Transactions 2022, no. 1 (2022): 1–12. http://dx.doi.org/10.37705/techtrans/e2022009.
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This article is devoted to the analysis of contemporary Polish multi-family architecture in the context of aesthetic irregularity. The research was limited to constructions from 2011–2021 and nominated for the Mies van der Rohe award as the objects with the greatest potential impact on shaping further trends. In their research, the authors focused on searching for the features of irregularities, which, in their opinion, have become a distinguishing feature of contemporary architectural aesthetics. The analyses in this study refer to three planes of the aesthetic dimension of architecture, namely the form, facade composition and material.
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Frohburg, Jan. "Ellington under Glass." BAc Boletín Académico. Revista de investigación y arquitectura contemporánea 9 (November 4, 2019): 45–68. http://dx.doi.org/10.17979/bac.2019.9.0.4582.
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In November 1957 Mies van der Rohe’s Crown Hall at IIT broke with convention when it became the venue for a jazz concert by Duke Ellington and his orchestra. This extraordinary event is reconstructed based on personal recollections, campus newspapers and other archival material. In the context of architectural pedagogy Crown Hall is appreciated as a supreme expression of Mies’s architectural philosophy, both for its spatial openness and its spiritual character. Here, influences from Mies’s own evolution as an architect intersected with developments in modern music and performance art it inspired. Parallels are uncovered between Ellington’s jazz and Mies’s steel and glass architecture, both distinctly American idioms that characterise post-war modernity. The Ellington concert at Crown Hall presented the perfect synthesis of people, space, light, music and nature. At the same time it attested to the disruptive potential that exists in jazz and modern architecture alike.
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Weber, C., and J. Königsberger. "Industrie 4.0: Aktuelle Entwicklungen für Analytics*/Industrie 4.0: Current Advances in Analytics - Part 1: Analytics and Data Management in Industrie 4.0 Reference Architectures." wt Werkstattstechnik online 107, no. 03 (2017): 113–17. http://dx.doi.org/10.37544/1436-4980-2017-03-9.
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Die Verarbeitung großer Datenmengen sowie die hohe Relevanz von Datenanalysen sind in den produzierenden Unternehmen mittlerweile angekommen. Bekannte Anwendungsbeispiele sind Digital Mock-Up in der Produktentwicklung oder Prozessoptimierung durch Predictive Maintenance. Die in letzter Zeit entwickelten Referenzarchitekturen in diesen breitgefächerten Themenfeldern betrachten dementsprechend verschiedene Aspekte in unterschiedlichen Ausprägungen. Dieser aus zwei Teilen bestehende Fachbeitrag rekapituliert und bewertet diese Entwicklungen, um Unternehmen bei der Umsetzung ihrer eigenen individuellen Architektur Hilfestellung zu geben. Im Teil 1 werden aktuelle Referenzarchitekturen mit ihren Architekturbausteinen im Bereich Industrie 4.0 vorgestellt. Im zweiten Teil (Ausgabe 6-2017 der wt Werkstattstechnik online) werden die Referenzarchitekturen unter dem Gesichtspunkt der Themenfelder Analytics sowie Datenmanagement untersucht und bewertet. &nbsp; The processing of huge amounts of data as well as the importance of analytics on data have arrived in the manufacturing industry by now. Well-known usage examples are digital mock-ups in product engineering or process optimization through predictive maintenance. Recently developed reference architectures in these wide-ranging subject areas consider multiple aspects under different characteristics. This article recapitulates and evaluates these developments in two parts and aims to support companies in the implementation of their individual architecture. In this first part, current reference architectures for Industrie 4.0 are introduced. In the second part (to be pubished in issue 6-2017), these architectures are compared and assessed with regard to analytics and data management.
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Boyken, Immo, and Hans J. Oestmann. "Ludwig Mies van der Rohe and Egon Eiermann: The Dictate of Order." Journal of the Society of Architectural Historians 49, no. 2 (1990): 133–53. http://dx.doi.org/10.2307/990473.
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A comparison of the works of two of Germany's most important architects, Ludwig Mies van der Rohe and Egon Eiermann, reveals two similar but subtly different approaches to theory and design in the years following World War II. While there is no evidence of a close personal relationship between the two architects, their theoretical views were largely compatible. Both believed in the "universal validity" of pre-determined architectural forms, and they adhered closely to the principle of architectural "order." Eiermann's designs, however, are never as rigid as those of Mies, and he made many more allowances for technology and human need in his buildings. As a result, Eiermann's architecture is characterized today by a certain charm that sets it apart from the strict formalism of Mies van der Rohe.