Academic literature on the topic 'Drug Release Kinetics'

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Journal articles on the topic "Drug Release Kinetics"

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Chakraborty, Santanu, Madhusmruti Khandai, Anuradha Sharma, Ch Patra, V. Patro, and Kalyan Sen. "Effects of drug solubility on the release kinetics of water soluble and insoluble drugs from HPMC based matrix formulations." Acta Pharmaceutica 59, no. 3 (2009): 313–23. http://dx.doi.org/10.2478/v10007-009-0025-8.

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Effects of drug solubility on the release kinetics of water soluble and insoluble drugs from HPMC based matrix formulations The purpose of the present research work was to observe the effects of drug solubility on their release kinetics of water soluble verpamil hydrochloride and insoluble aceclofenac from hydrophilic polymer based matrix formulations. Matrix formulations were prepared by the direct compression method. The formulations were evaluated for various physical parameters. Along with the dynamics of water uptake and erosion, SEM and in vitro drug release of the tablets were studied.
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Nooreen, Hari kiriti varma G, and Vijayakuchana. "Formulation and in vitro evaluation of sustained release matrix tablets of Rimopride Citrate Dihydrate." Frontier Journal of Pharmaceutical Sciences and Research 7, no. 1 (2024): 1–5. https://doi.org/10.5281/zenodo.10575985.

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Drugs are most frequently administered by oral route. Although a few drugs taken orally are intended to be dissolved in the mouth, nearly all drugs taken orally are swallowed. A few drugs such as antacids are swallowed for their local action in the gastrointestinal tracts. Hence the above study demonstrated that combination of HPMC K4M and HPMC K15M can be used to formulate sustained release matrix tablets of Rimopride Citrate Dihydrate. This can sustain the drug release up to 24 hours as per standard dissolution profile. This can be expected to reduce the frequency of administration and decre
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Kumar, Putta Rajesh, Meena N, Poojitha P, Sowjanya P, Shivaleela U, and Sharma JVC. "Formulation Design and in Vitro Evaluation Studies of Antidepressant Venlafaxine Hydrochloride Oral Drug Delivery Systems." Journal of Biomedical and Pharmaceutical Research 13, no. 2 (2024): 51–63. http://dx.doi.org/10.32553/jbpr.v13i2.1084.

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Background: Venlafaxine Hydrochloride a serotonin, nor epinephrine reuptake inhibitor, oral antidepressant used to treat depression. Objective: The present study was aimed at studying controlled release of Venlafaxine Hydrochloride with Guargum, Hydroxy propyl methyl cellulose as matrix polymers, Micro crystalline cellulose as binder and Dicalcium phosphate as diluent filler. Methods: Tablets were studied for pre, post compression, swelling and in vitro dissolution studies. Drug release was analyzed by release kinetic models. Results: Preformulation studies revealed that the drug procured was
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Zhu, Weiwei, Jiajie Long, and Meiwu Shi. "Release Kinetics Model Fitting of Drugs with Different Structures from Viscose Fabric." Materials 16, no. 8 (2023): 3282. http://dx.doi.org/10.3390/ma16083282.

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(1) Background: It is simpler and more environmentally friendly to use supercritical CO2 fluid technology to process skincare viscose fabrics. Therefore, it is significant to study the release properties of drug-loaded viscose fabrics to choose suitable skincare drugs. In this work, the release kinetics model fittings were investigated in order to clarify the release mechanism and provide a theoretical basis for processing skincare viscose fabrics with supercritical CO2 fluid. (2) Methods: Nine kinds of drugs with different substituent groups, different molecular weights, and different substit
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Arefin, Paroma, Ikramul Hasan, Md Shfiqul Islam, and Md Selim Reza. "Formulation and In vitro Evaluation of Eudragit RL 100 Loaded Fexofenadine HCl Microspheres." Bangladesh Pharmaceutical Journal 19, no. 1 (2016): 58–67. http://dx.doi.org/10.3329/bpj.v19i1.29240.

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The present study deals with the formulation and evaluation of Fexofenadine hydrochloride (HCl) loaded sustained release microspheres by emulsion solvent evaporation method with Eudragit RL 100. The effects of percent drug loading on drug encapsulation efficiency, drug content and drug release rate were assessed. In vitro dissolution study was performed spectrophotometrically according to USP paddle method using phosphate buffer (pH 6.8) for 10 hours. The release rate of Fexofenadine HCl from the microspheres was significantly increased with the increase of drug loading. The drug release patte
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Mitran, Raul-Augustin, Daniela Berger, Jeanina Pandele-Cusu, and Cristian Matei. "Effect of Aluminum Incorporation into Mesoporous Aluminosilicate Framework on Drug Release Kinetics." Journal of Nanomaterials 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/9864396.

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Mesoporous silica materials are promising nanocarriers for the development of drug delivery systems. In this study, the influence of pore size, volume, surface area, and doping the silica framework on the release kinetics of a model drug, metoprolol, has been studied. 20% or 50% wt. therapeutic agent was loaded into the carrier mesopores through incipient wetness impregnation. The carriers and drug-loaded samples have been characterized by small- and wide-angle X-ray diffraction, FT-IR spectroscopy, scanning electron microscopy, and nitrogen adsorption-desorption isotherms. The in vitro releas
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Suprianto. "Analisis Kinetika Pelepasan Teofilin dari Granul Matriks Kitosan." JURNAL ILMIAH MANUNTUNG 2, no. 1 (2016): 70–80. https://doi.org/10.5281/zenodo.1246129.

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Moment the drug dosage form development, it is important to study the drug release or dissolution that is recognized as an element in drug development. Mathematical models could help optimize the design of drugs to produce models of drug release information. Analysis of quantitative values obtained when depicting dissolution drug release profiles more easily when the mathematical concepts used to describe the drug release kinetics model. The model release of drugs known includes zero order, first order, Higuchi models, models Hixon Crowell and Peppas Korsmeyer models. The purpose of this
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Dumitriu, Raluca Petronela, Ana Maria Oprea, and Cornelia Vasile. "Kinetics of Swelling and Drug Release from PNIPAAm/Alginate Stimuli Responsive Hydrogels." Solid State Phenomena 154 (April 2009): 17–22. http://dx.doi.org/10.4028/www.scientific.net/ssp.154.17.

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Stimuli responsive hydrogels are very attractive for applications in sustained and/or targeted drug delivery systems. As the release of drugs is related to the swelling behavior of hydrogels, the swelling kinetic studies become of great importance to appreciate the release kinetics from hydrogel matrices. Hydrogels with high performance properties have been prepared from N-isopropylacryl amide (NIPAAm) and sodium alginate, crosslinked with N,N`-methylene-bis-(acrylamide) (MBAAm). This study is focused on the investigation of swelling and drug release kinetics, coupled by morphological studies.
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Das, Utpal, Shimul Halder, Abul Kalam Lutful Kabir, Harun Or Rashid, and Abu Shara Shamsur Rouf. "Development and in vitro Evaluation of Sustained Release Matrix Tablets of Indapamide from Methocel® K15 MCR and K100 LVCR." Dhaka University Journal of Pharmaceutical Sciences 10, no. 2 (2012): 87–92. http://dx.doi.org/10.3329/dujps.v10i2.11785.

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Indapamide, a low-dose thiazide-type diuretic, is used for the treatment of essential hypertension. In this study, we developed an indapamide sustained release formulation using Methocel K15 MCR (a modified hydroxypropyl methylcellulose), Methocel K100 LVCR (a modified hydroxypropyl methylcellulose), magnesium stearate, talc and starch 1500 by direct compression. The powders for tableting were evaluated for angle of repose, loose bulk density, tapped bulk density, compressibility index, total porosity etc. The tablets were subjected to thickness, weight variation test, hardness, friability and
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Loew, Stephan, Alfred Fahr, and Sylvio May. "Modeling the Release Kinetics of Poorly Water-Soluble Drug Molecules from Liposomal Nanocarriers." Journal of Drug Delivery 2011 (June 7, 2011): 1–10. http://dx.doi.org/10.1155/2011/376548.

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Liposomes are frequently used as pharmaceutical nanocarriers to deliver poorly water-soluble drugs such as temoporfin, cyclosporine A, amphotericin B, and paclitaxel to their target site. Optimal drug delivery depends on understanding the release kinetics of the drug molecules from the host liposomes during the journey to the target site and at the target site. Transfer of drugs in model systems consisting of donor liposomes and acceptor liposomes is known from experimental work to typically exhibit a first-order kinetics with a simple exponential behavior. In some cases, a fast component in t
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Dissertations / Theses on the topic "Drug Release Kinetics"

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Jones, Stephen Joseph. "Investigating nonlinear enzyme kinetics as an internal control system for nanoreactor drug release." Thesis, University of Leeds, 2018. http://etheses.whiterose.ac.uk/22207/.

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The improper administration of therapeutic compounds is not only financially inefficient, but, there exists a very real risk of harmful, or potentially life-threatening effects. To gain control, nano-drug delivery systems provide a discernible option for temporal and spatial regulation of drug bioavailability within the body. In current regimes, temporal control is realised through gradual release over an extended period of time, or triggered release in response to a change in the physiochemical environment. Of course, when considering the design of an ideal drug delivery system, we think of a
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He, Xingyu. "Long-term Light-activated Drug Delivery Systems." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1613752062550859.

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Fugit, Kyle Daniel. "QUANTIFICATION OF FACTORS GOVERNING DRUG RELEASE KINETICS FROM NANOPARTICLES: A COMBINED EXPERIMENTAL AND MECHANISTIC MODELING APPROACH." UKnowledge, 2014. http://uknowledge.uky.edu/pharmacy_etds/37.

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Advancements in nanoparticle drug delivery of anticancer agents require mathematical models capable of predicting in vivo formulation performance from in vitro characterization studies. Such models must identify and incorporate the physicochemical properties of the therapeutic agent and nanoparticle driving in vivo drug release. This work identifies these factors for two nanoparticle formulations of anticancer agents using an approach which develops mechanistic mathematical models in conjunction with experimental studies. A non-sink ultrafiltration method was developed to monitor liposomal rel
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Liu, Quan. "Development of a novel gastro-retentive delivery system using alfuzosin HCl as a model drug." Diss., Temple University Libraries, 2010. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/80170.

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Pharmaceutics;<br>Ph.D.<br>The objectives of this project encompass the design and development of a drug delivery system to continuously deliver therapeutic agents from the stomach to the proximal region of the intestine. The delivery system designed would have sufficient gastric residence time together with near zero-order release kinetics. The physicochemical properties pertaining to the formulation development of the model drug (alfuzosin HCl) were evaluated. Excipients were selected based on the studies of their physicochemical properties and compatibility with the active ingredient. Gast
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Modi, Sweta. "The Critical Role of Mechanism-Based Models for Understanding and Predicting Liposomal Drug Loading, Binding and Release Kinetics." UKnowledge, 2013. http://uknowledge.uky.edu/pharmacy_etds/19.

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Liposomal delivery systems hold considerable promise for improvement of cancer therapy provided that critical formulation design criteria can be met. The main objective of the current project was to enable quality by design in the formulation of liposomal delivery systems by developing comprehensive, mechanism-based mathematical models of drug loading, binding and release kinetics that take into account not only the therapeutic requirement but the physicochemical properties of the drug, the bilayer membrane, and the intraliposomal microenvironment. Membrane binding of the drug affects both dru
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Cui, Yong. "Enhanced Release of Lidocaine From Supersaturated Solutions of Lidocaine In A Pressure Sensitive Adhesive." The Ohio State University, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=osu1054210962.

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Pavurala, Naresh. "Oral Drug Delivery -- Molecular Design and Transport Modeling." Diss., Virginia Tech, 2013. http://hdl.handle.net/10919/53505.

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One of the major challenges faced by the pharmaceutical industry is to accelerate the product innovation process and reduce the time-to-market for new drug developments. This involves billions of dollars of investment due to the large amount of experimentation and validation processes involved. A computational modeling approach, which could explore the design space rapidly, reduce uncertainty and make better, faster and safer decisions, fits into the overall goal and complements the product development process. Our research focuses on the early preclinical stage of the drug development process
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GUPTA, PREETI. "HYDROGEL BASED WOUND DRESSING MATERIAL." Thesis, DELHI TECHNOLOGICAL UNIVERSITY, 2021. http://dspace.dtu.ac.in:8080/jspui/handle/repository/18806.

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Weak mechanical strength of hydrogels in wet condition limits their use for load bearing applications. Their mechanical strength can be raised by grafting them over some support or by converting them into nanofibrous form. Present thesis is focused on the preparation of poly (acrylamide-co-acrylic acid) hydrogel grafted over cotton fabric using two different cross-linkers i.e. PEG and MBAAm for making medicated dressing and nanofibers of hydrogel of poly (acrylamide-co-acrylic acid). FTIR was used to confirm the insertion of cross-links into the polymer chains. Grafting of uniform hydro
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Lee, Tak-yee. "Part 1: Computer aided dosage form design: theory and applications. Part 2: Kinetics and mechanism of captopril oxidation in aqueous solutions under controlled oxygen partial pressure /." The Ohio State University, 1986. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487266011224445.

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Jacob, Dolly. "Investigation into reliability and performance of an implantable closed-loop insulin delivery device." Thesis, De Montfort University, 2014. http://hdl.handle.net/2086/11126.

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An implantable closed-loop insulin delivery device (INsmart device) containing a glucose responsive gel has been developed within the INsmart research group, over a period of 10 years, to mimic pancreas. In this thesis, the reliability and performance capability of the INsmart device was studied for future clinical use. Investigations into the device material compatibility with insulin solution, assessed by monitoring insulin loss and degradant formation over a period of 31 days using RP-HPLC have shown that stainless steel and titanium are the most compatible materials. Polycarbonate contribu
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Books on the topic "Drug Release Kinetics"

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Cavacuiti, Christopher. The Pharmacology of Opioids (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190265366.003.0008.

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This chapter focuses on the attributes of and component medications within the class of opioids, emphasizing kinetics, dynamics, and therapeutic and adverse effects. To help patients make informed decisions about opioid use, the clinicians prescribing these medications must be able to explain when opioids are likely to help and when they are likely to do harm. Subclasses of opioids include phenanthrenes, benzomorphans, phenylpiperidines, and diphenylheptanes; examples are given of each, with respective utilities and limitations. A discussion then follows of pharmacodynamics, pharmacokinetics,
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Book chapters on the topic "Drug Release Kinetics"

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Colombo, Paolo, Gaia Colombo, and Christine Cahyadi. "Geometric Release Systems: Principles, Release Mechanisms, Kinetics, Polymer Science, and Release-Modifying Material." In Controlled Release in Oral Drug Delivery. Springer US, 2011. http://dx.doi.org/10.1007/978-1-4614-1004-1_11.

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Lee, Ping I. "Kinetics of Drug Release from Glassy Polymers: Effect of Initially Nonuniform Drug Distribution." In Polymeric Materials in Medication. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4899-2245-8_7.

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Grabow, N., S. Siewert, K. Sternberg, H. Martin, and K. P. Schmitz. "Simulation of Drug Release for the Development of Drug-Eluting Stents - Influence of Design and Manufacturing Parameters on Drug Release Kinetics." In IFMBE Proceedings. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03887-7_40.

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Delfour, Michel C., and André Garon. "Quadratic ODE and PDE Models of Drug Release Kinetics from Biodegradable Polymers." In IFIP Advances in Information and Communication Technology. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36062-6_2.

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Sukhodub, L. B., M. O. Kumeda, and L. F. Sukhodub. "Influence of MW Irradiation on the Hydroxyapatite/Chitosan Composite Structure and Drug Release Kinetics." In IFMBE Proceedings. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-31866-6_64.

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Lee, Ping I. "Interpretation of Drug-Release Kinetics from Hydrogel Matrices in Terms of Time-Dependent Diffusion Coefficients." In ACS Symposium Series. American Chemical Society, 1987. http://dx.doi.org/10.1021/bk-1987-0348.ch005.

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Mohd Sabee, M. M. S., and Z. A. Abdul Hamid. "Comparison of Gentamicin and Dexamethasone Release Kinetics from Poly(Lactic Acid) (PLA) Microspheres for Drug Delivery Systems." In Springer Proceedings in Materials. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-2015-0_11.

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Caldwell, J., and S. A. Hotchkiss. "In vivo Dissolution and Absorption Kinetics of Sustained-Release Theophylline, Studied with Stable Isotope Methodology." In Drug Absorption at Different Regions of the Human Gastro-Intestinal Tract: Methods of Investigation and Results / Arzneimittelabsorption aus verschiedenen Bereichen des Gastrointestinaltraktes beim Menschen: Untersuchungsmethoden und Ergebnisse. Vieweg+Teubner Verlag, 1987. http://dx.doi.org/10.1007/978-3-322-91091-2_4.

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Woodcock, B. G., G. Menke, A. Fischer, H. Köhne, and N. Rietbrock. "Drug Input Rate from the GI-Tract. Michaelis-Menten Kinetics and the Bioavailability of Slow-Release Verapamil and Nifedipine." In Drug Absorption at Different Regions of the Human Gastro-Intestinal Tract: Methods of Investigation and Results / Arzneimittelabsorption aus verschiedenen Bereichen des Gastrointestinaltraktes beim Menschen: Untersuchungsmethoden und Ergebnisse. Vieweg+Teubner Verlag, 1987. http://dx.doi.org/10.1007/978-3-322-91091-2_16.

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Mandal, Akash Pradip, and Prashanta Kumar Mandal. "Role of Stent Embedment and Release Kinetics on Two-Phase Binding of Drug in a Three-Layered Arterial Tissue." In Intelligent Systems and Simulation. CRC Press, 2025. https://doi.org/10.1201/9781003638414-10.

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Conference papers on the topic "Drug Release Kinetics"

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Keo, Van Dong, Xuan Tran Hiep, Quoc Nguyen Banh, Tran Anh Son, and Duong Huyen Lynh. "Determination of Geometrical Parameters to Balance the Pressure Drop of Channels on a Microfluidic Chip." In 2024 International Conference on Machining, Materials and Mechanical Technologies. Trans Tech Publications Ltd, 2025. https://doi.org/10.4028/p-me24oh.

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In the past few years, micro-droplets have been widely used in diverse fields of biological and chemical research, spanning from drug delivery and material synthesis to point-of-care diagnostics, digital PCR, and single-cell analysis. Droplet-based microfluidics offers a powerful platform for conducting complex experiments, screening processes, and analyses with enhanced precision, efficiency, and versatility. While creating droplets with uniform sizes is a common objective of microfluidics, it is not limited to producing droplets of a single size per chip. Creating microdroplets with differen
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Swaroop, K., and H. M. Somashekarappa. "Swelling characteristics and drug release kinetics of Ag/PVA hydrogel nanocomposites." In DAE SOLID STATE PHYSICS SYMPOSIUM 2016. Author(s), 2017. http://dx.doi.org/10.1063/1.4980807.

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Wang Hong and Hongyu Chen. "Study of the drug release kinetics in nanoscale micelle to micelle system." In 2010 IEEE 3rd International Nanoelectronics Conference (INEC). IEEE, 2010. http://dx.doi.org/10.1109/inec.2010.5424875.

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Shaikenov, Roman, Vladislava Klimshina, Yuliya Generalova, et al. "Electrospun Hyaluronan-Based Nanofibers with Mangiferin: Preparation, Morphology, and Drug Release Kinetics." In IOCBE 2024. MDPI, 2024. http://dx.doi.org/10.3390/engproc2024081002.

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Teletina, Karmelina, Nikola Fišić, Maja Ranković, Jelena Rupar, Maja Milojević-Rakić, and Anka Jevremović. "INVESTIGATION OF THE RELEASE OF NOVEL ACRIDINE DERIVATIVE SUPPORTED ONTO Y ZEOLITE." In 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry. Society of Physical Chemists of Serbia, 2024. https://doi.org/10.46793/phys.chem24i.321t.

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This study investigated 2-(acridin-9-ylamino)-3-(1H-indol-3-yl)propanoic acid, acridine derivative as a potential anticancer drug supported on FAU type zeolite Y. Y zeolite before and after the drug impregnation was characterized with the scanning electron microscopy and thermogravimetry, while HPLC/FL and spectrofluorimetry were employed for drug quantification. The morphology of the zeolite did not change during the drug impregnation process, and the resulting drug loading was 17.9 mg/g. The release of 1.2 µM acridine derivative concentration necessary for targeted cancer cytotoxicity and fa
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Berchane, Nader S., Kenneth H. Carson, Allison C. Rice-Ficht, and Malcolm J. Andrews. "Investigation of Drug Release From Biodegradable PLG Microspheres: Experiment and Theory." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176030.

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Piroxicam containing PLG microspheres having different size distributions were fabricated, and in vitro release kinetics were determined for each preparation. Based on the experimental results, a suitable mathematical theory has been developed that incorporates the effect of microsphere size distribution and polymer degradation on drug release. We show from in vitro release experiments that microsphere size has a significant effect on drug release rate. The initial release rate decreased with an increase in microsphere size. In addition, the release profile changed from first order to concave-
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Grattoni, Alessandro, Xuewu Liu, Zongxing Wang, Jaskaran Gill, Arturas Ziemys, and Mauro Ferrari. "Electrokinetic Transport of Molecules Through Nanochanneled Membranes." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13236.

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Our research group was the first one to microfabricate and demonstrate nano-channels in silicon membranes (1, 2). We employed nano-channeled chips to provide immuno-isolation for cell transplantation towards the treatment of diabetes (3), for biomolecular separation (4), and for the controlled passive and active release of drug molecules from implanted capsules (5). We showed that the constraints placed upon molecular agitation in nano-channels affected their concentration-driven transport kinetics (6, 7). A zero-order passive release of biological molecules was achieved, by the rational tailo
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Perkins, Jessica L., Salil Desai, Benjamin Harrison, and Jagannathan Sankar. "Understanding Release Kinetics of Calcium Alginate Microcapsules Using Drop on Demand Inkjet Printing." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-12819.

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This paper investigates the use of calcium alginate microcapsules to transport biomaterials for drug delivery. Rhodamine 6G dye was encapsulated in microcapsules for different formulations of the hydrogels using drop-on-demand printing. An experimental design was constructed to compare the effect of different concentrations of calcium chloride (M) and sodium alginate (% w/v) solutions in addition to the microcapsule diameter on the release kinetics profiles of the microcapsules. The results of these findings provide a basis to identify favorable sizes of microcapsules and concentrations of sod
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ginistrelli, Edoardo, Cecilia Bertiond, Davide Janner, et al. "Hollow resorbable fiber for combined light and drug delivery: fiber development and analysis of release kinetics." In Novel Biophotonics Techniques and Applications IV, edited by Arjen Amelink and I. Alex Vitkin. SPIE, 2017. http://dx.doi.org/10.1117/12.2284313.

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Ulfa, Maria, Rufaida M. Hasanah, and Didik Prasetyoko. "Release kinetics performance of ibuprofen molecule from ordered mesoporous carbon with deferent concentration of drug loading." In 2ND INTERNATIONAL CONFERENCE ON CHEMISTRY, CHEMICAL PROCESS AND ENGINEERING (IC3PE). Author(s), 2018. http://dx.doi.org/10.1063/1.5064961.

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Reports on the topic "Drug Release Kinetics"

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Noel, Erika, Giulia Mattana, and Anthony McGoron. A Comparative Analysis of Nanoparticle Sizing Techniques for Enhanced Drug Delivery Applications. Florida International University, 2025. https://doi.org/10.25148/fiuurj.3.1.5.

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Nanoparticle-based drug delivery systems hold promise for improving therapeutic efficacy and targeting precision. However, a critical challenge in their development is ensuring size stability, as particle size directly influences biodistribution, cellular uptake, and drug release profiles. This study establishes a streamlined methodology to assess nanoparticle size consistency by comparing three widely used characterization techniques: Dynamic Light Scattering (DLS), Transmission Electron Microscopy (TEM), and Nanoparticle Tracking Analysis (NTA). Two types of nanoparticles were analyzed: 100
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Chutimaworapan, Suchada, Chaiyo Chaichantippayuth, and Areerat Laopaksa. Formulation of pharmaceutical products of Garcinia mangostana Linn. extracts. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.32.

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Part I: The purpose of the investigation was to develop the extraction process that was simple, practical and giving high yield. The maceration of dried powder of Garcinia mangostana fruit husk with ethyl acetate gave yellow crystalline powder of mangostin. The yield was calculated as 7.47%. The identification of the Garcinia mangostanahusk extract was carried out by thin-layer chromatography (TLC) and differential scanning calorimetry. The TLC of mangostin was done by using the alumina sheet and ethyl acetate: hexane (3:1) as mobile phase. The Rf value as compared with standard mangostin was
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