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1

Dawson, Michael. "Expiry dates." Australian Prescriber 17, no. 2 (1994): 46–48. http://dx.doi.org/10.18773/austprescr.1994.051.

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2

Pimm, Stuart. "Expiry dates." Nature 426, no. 6964 (2003): 235–36. http://dx.doi.org/10.1038/426235a.

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3

Atkinson, J. "Expiry dates on opened injectables." Veterinary Record 164, no. 1 (2009): 29–30. http://dx.doi.org/10.1136/vr.164.1.29-b.

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Atkinson, J. "Expiry dates on opened injectables." Veterinary Record 164, no. 1 (2009): 30. http://dx.doi.org/10.1136/vr.164.1.30-b.

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5

Philip, A. B., M. O'Sullivan, and S. Mannion. "Medical gas cylinder expiry dates." Anaesthesia 73, no. 1 (2017): 129. http://dx.doi.org/10.1111/anae.14153.

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6

Stewart, Alex G. "Expiry Dates on Drug Packages." Tropical Doctor 27, no. 3 (1997): 191. http://dx.doi.org/10.1177/004947559702700339.

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7

Hogerzeil, HansV, and GodfreyJ A. Walker. "DRUG EXPIRY DATES, STORAGE, AND POTENCY." Lancet 332, no. 8619 (1988): 1083. http://dx.doi.org/10.1016/s0140-6736(88)90106-7.

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8

Khan, Tareq. "Expiry Date Digit Recognition using Convolutional Neural Network." European Journal of Electrical Engineering and Computer Science 5, no. 1 (2021): 85–88. http://dx.doi.org/10.24018/ejece.2021.5.1.259.

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The expiry dates printed on the merchandise have a distinct background, font, alignment, and color in comparison with the available handwritten digit datasets. In this paper, an expiry date dataset is used, and also a convolutional neural network (CNN) model is proposed to recognize expiry dates out of images. This model may be employed together with our previously proposed smart expiry architecture to get an automated notification to the smartphone for the foods which are expiring soon. The suggested deep learning model is tested and has a classification accuracy of 90%.
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9

GaBI Journal Editor. "Patent expiry dates for best-selling biologicals." Generics and Biosimilars Initiative Journal 4, no. 4 (2015): 178–79. http://dx.doi.org/10.5639/gabij.2015.0404.040.

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GaBI Journal Editor. "Patent expiry dates for biologicals: 2016 update." Generics and Biosimilars Initiative Journal 6, no. 1 (2017): 27–30. http://dx.doi.org/10.5639/gabij.2017.0601.006.

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GaBI Journal Editor. "Patent expiry dates for biologicals: 2017 update." Generics and Biosimilars Initiative Journal 7, no. 1 (2018): 29–34. http://dx.doi.org/10.5639/gabij.2018.0701.007.

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GaBI Journal Editor. "Patent expiry dates for biologicals: 2018 update." Generics and Biosimilars Initiative Journal 8, no. 1 (2019): 24–31. http://dx.doi.org/10.5639/gabij.2019.0801.003.

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13

Nathanson, M. "Medical gas cylinder expiry dates - a reply." Anaesthesia 73, no. 1 (2017): 129–30. http://dx.doi.org/10.1111/anae.14154.

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14

Rabuñal-Alvarez, M., E. Fernandez-Gabriel, M. Calvin-Lamas, and M. Martin-Herranz. "OHP-001 Analysis of investigational products expiry dates." European Journal of Hospital Pharmacy 22, Suppl 1 (2015): A187.2—A187. http://dx.doi.org/10.1136/ejhpharm-2015-000639.450.

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15

Friday, Ebole, and Tiamiyu Sorlihu. "Automated Drug Expiry Detection and Alert System Via Email Notifications." American Journal of Networks and Communications 14, no. 1 (2025): 1–9. https://doi.org/10.11648/j.ajnc.20251401.11.

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Effective pharmaceutical management is vital for healthcare systems, where timely identification of drug expiry dates is crucial to ensure patient safety and regulatory compliance. This paper presents an automated system for drug expiry date detection and email alerting, aimed at enhancing the efficiency and reliability of pharmaceutical management. Traditional manual tracking methods are often prone to errors and inefficiencies, leading to potential health risks. The proposed system automates this process, ensuring prompt notifications to relevant stakeholders. The system features a centralized database for storing drug information, barcode or QR code scanning for data entry, an expiry date detection algorithm, and an integrated email alerting mechanism. The database, managed using MySQL, contains detailed records of each drug, including its name, batch number, manufacturing date, expiry date, and quantity. Barcode or QR code scanners facilitate quick and accurate updates to the database, implemented through a Python-based application. The expiry date detection algorithm runs periodically, comparing current dates with stored expiry dates to identify drugs nearing expiration within a specified threshold, typically 30 days. Upon detection, the system triggers email alerts with detailed drug information sent to pharmacists, healthcare providers, and inventory managers, prompting timely action to prevent the use of expired medications. Testing in a controlled environment with a sample dataset demonstrated that the algorithm accurately identified drugs nearing expiry and generated appropriate email alerts. User feedback indicated significant improvements in efficiency and a reduced risk of expired drug usage. This automated system offers a proactive approach to managing drug inventories, minimizing human error, and enhancing compliance with health regulations. By automating expiry date tracking and alerting, it improves pharmaceutical safety and streamlines inventory management. Future enhancements could include additional notification methods, such as SMS alerts, and expanding the system’s capabilities to manage other aspects of pharmaceutical inventory.
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Krasnova, I. S., V. I. Ganina, G. V. Semenov, I. I. Ionova, and Z. L. Guchok. "Determination the expiry dates of fermented freezedried milk product." DAIRY INDUSTRY, no. 3 (2023): 46–48. http://dx.doi.org/10.31515/1019-8946-2023-03-46-48.

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17

Abhiram, A., Saju Arjun, S. Nair Hemanth, Shankar Manu, and Ajesh F. Dr. "Expiry Notification System Using QR CodeScanning." Research and Reviews: Advancement in Cyber Security 1, no. 3 (2024): 36–41. https://doi.org/10.5281/zenodo.13383039.

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<em>Food waste stands as a pressing global issue, exacerbated by the common occurrence of consumers forgetting about the expiry dates of purchased food items, ultimately leading to unnecessary disposal. The consequences of such waste extend beyond the economic and environmental realms, encompassing severe health risks associated with the consumption of expired products. To address this multifaceted challenge, this paper proposes a holistic solution in the form of a smart expiry system, strategically designed to tackle the root cause of consumer forgetfulness. The system operates by leveraging technology to automatically dispatch timely notifications to customers' smartphones, prompting them about upcoming expirations several days in advance. The intricacies of system implementation involve the checkout operator app generating a comprehensive table, encapsulating product names, respective expiry dates, and a QR code conveniently printed on the purchase receipt. Upon completing the purchase, consumers engage with a dedicated smartphone app, employing a simple yet effective process of scanning a single QR code. This action triggers the update of the customer's Google calendar with the expiry dates of the purchased items, seamlessly integrating the information into their digital lives. This approach not only addresses the immediate challenge of forgetfulness but also holds the potential to reshape consumer habits towards more responsible food consumption. By intertwining technological advancements, heightened consumer awareness, and sustainable practices, the proposed system aspires to transcend its role as a mere expiration reminder. It envisions a comprehensive strategy for mitigating food waste, fostering sustainable consumption patterns, and contributing to a larger narrative of responsible resource management. In essence, this paper seeks to emphasize the interconnectedness of various elements in the battle against food waste. Beyond the logistical aspects of system implementation, it delves into the psychological dimensions of consumer behavior, exploring the reasons behind forgetfulness and proposing strategies to enhance consciousness about food expiration. Moreover, the integration of QR code technology is not merely a logistical solution but opens the door to broader applications, potentially improving traceability and transparency throughout the food supply chain.</em>
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18

Custers, Bart. "Click here to consent forever: Expiry dates for informed consent." Big Data & Society 3, no. 1 (2016): 205395171562493. http://dx.doi.org/10.1177/2053951715624935.

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19

Turdiyeva, Zilola Vakhobdjanovna Anvarova Farangiz Jamshidovna Yunusova Kholida Mannanovna. "STUDYING THE STORAGE CONDITIONS AND EXPIRY DATES OF "SEDTAB" TABLETS." INTERNATIONAL BULLETIN OF APPLIED SCIENCE AND TECHNOLOGY 3, no. 5 (2023): 817–21. https://doi.org/10.5281/zenodo.7961007.

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The analysis of the recommended sedative tablets was carried out. The stability and expiration dates of the recommended Sedtab tablets were carried out by the method of conventional storage and the method of &quot;accelerated aging&quot; according to temporary instructions I-42-2-82 at a temperature of 40 &deg; C. Recommendations were prepared as a result of the studies, the obtained data on the determination of the shelf life of the recommended tablets. These recommendations are intended for both developers and manufacturers of dosage forms.
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20

Davido, Benjamin, Hugues Michelon, Christel Mamona, Pierre de Truchis, Karim Jaffal, and Azzam Saleh-Mghir. "Efficacy of Expired Antibiotics: A Real Debate in the Context of Repeated Drug Shortages." Antibiotics 13, no. 5 (2024): 466. http://dx.doi.org/10.3390/antibiotics13050466.

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This narrative review aims to discuss the main interest in and cautions associated with the use of expired antibiotics in the context of repeated shortages, notably in Europe. Articles concerning the topic of expiry dates related to antibiotic use were reviewed using keywords in the PubMed®/MEDLINE and Google Scholar databases to identify the most extensive evidence-based documentation. The present review evaluates the potential interest and efficacy of using expired drugs and their possible related adverse events. Overall, in the context of drug shortages, expiry dates could be safely extended for at least one year for most solid antibiotics (tablets or powder) used in daily clinical practice, as long as they are stored under the right conditions, in accordance with the summary of product characteristics.
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21

Moll, Tomasz. "EXPIRY OF THE COUNCILOR’S MANDATE – SELECTED ISSUES." Roczniki Administracji i Prawa 2, no. XX (2020): 139–56. http://dx.doi.org/10.5604/01.3001.0014.1694.

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This study deals with selected legal issues related to the expiration of the councilor’s mandate, namely circumstances causing this legal effect (death, loss of electoral right or not having election day, refusal to take the oath, written resignation of the mandate, violation of the statutory prohibition of joining a councilor’s mandate with the performance of certain in separate regulations of the function or activity, selection to the head of a municipality, failure to submit a statement on its financial status as specified in separate regulations), procedure, dates and forms of expiry and obligations of the authorities in this respect
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22

Dexter, Jasmine, Melanie Morrow, Kelly Fogarty, and Abigail Trewin. "Disaster Preparedness Technician = Striking Cost Savings." Prehospital and Disaster Medicine 34, s1 (2019): s122—s123. http://dx.doi.org/10.1017/s1049023x19002632.

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Introduction:The workplace holds a rapidly deployable, self-sufficient field hospital including a medicine cache valued at $80,000. The cache is rotated through the affiliated hospital pharmacy when they have less than 12 months to their expiry. Rotations are done regularly due to the short expiry dates of stock coming from suppliers. A senior pharmacy technician is employed two days per week at a cost of $13,024.80 per annum to manage this cache.Aim:To demonstrate the associated cost savings of employing a pharmacy technician to manage a medication cache.Methods:Every month, the technician extracts items with less than a year expiry from the stock control system and compares these dates with that of the stock held in the pharmacy. All items with a better expiry date are rotated as long as there is sufficient turnover to ensure use before its expiry. Automatic recording occurs of items rotated, items discarded, and their costs are used as key performance indicators (KPI).Results:Over a 12 month period, $52,803 worth of stock was rotated. On average, 48 lines and 7,619 individual items were rotated monthly with a value of $4,061.83 (range $0-$8,820 per month). During this period, there were 2 months where no rotations occurred due to staff changeover and annual leave. 10 lines of medicines at a value of $4,041 were discarded over this time period. The two main reasons for discarding were that the medicine was not a pharmacy item or was not used in a large enough quantity to allow rotation.Discussion:The equivalent of four times the technician’s wage was saved over 12 months. This illustrates striking cost savings gained by efficient, timely rotations and the cost benefits of employing a technician.
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23

Valavan, Ramachandran, and Amarilys Cesar. "Current Status of Expiry of Homeopathic Medicines in Brazil, Germany, India and the United States: A Critical Review." Homeopathy 108, no. 04 (2019): 232–39. http://dx.doi.org/10.1055/s-0039-1692208.

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Background Assignment of expiry date to homeopathic medicines is a subject of important concern to its pharmacists and practitioners. This study compares the regulatory framework for the expiry of homeopathic medicines in four countries: Brazil, Germany, India and the United States. Findings Different or no expiry periods are variously followed. Whereas Germany, with some exceptions, employs a maximum expiry of 5 years for both potencies and finished products, Brazil adopts a 5-year expiry for finished products only, potencies used in manufacture being exempted from an assigned expiry date. In India, all homeopathic medicines except dilutions and back potencies have a maximum of 5 years' shelf-life, including those supplied to consumers. In the United States, homeopathic medicines are exempted from expiry dates. Comments There is neither a rational basis nor scientific evidence for assigning a short (3–5 years) expiry period for homeopathic medicines as followed in some of the countries, particularly in light of the fact that some studies have shown homeopathic medications to be effective even after 25 years. Homeopathic ultra-dilutions seem to contain non-material activity that is maintained over time and, since these exhibit different chemical properties compared to the original starting material, it is quite possible they possess properties of longer activity than conventional medicines. Regulators should acknowledge this feature and differentiate expiry of homeopathic medicinal products from that of conventional drugs.
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24

William, W., T. J. Ai, and W. Lee. "A Joint Replenishment Inventory Model to Control Multi-Item Medicines with Consideration of Space Requirements in the Hospital." International Journal of Industrial Engineering and Engineering Management 2, no. 2 (2020): 39–48. http://dx.doi.org/10.24002/ijieem.v2i2.4190.

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Medicines can be considered the most widely used medical expenditures in hospitals. To reduce the medicines expenses in the hospital, the term of inventory control is applied. Medicines must be controlled by considering the expiry dates and the probabilistic demand from the customers. Therefore, it is necessary to develop an inventory model that can be suitable to control medicines by minimizing the expired medicines, total inventory costs, and dealing with unpredictable demand. The purpose of this research is to develop an inventory model for determining optimum replenishment time and order quantities and space requirements for multi-item medicines with consideration of expiry dates of the medicines and all medicines are being purchased in a single purchase order so that the total inventory costs in hospitals can be minimized. The result is that the proposed inventory model results in optimum space requirements and the lowest inventory costs. Therefore, hospitals must order medicines based on the optimum order quantity.
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Rebedea, Traian, and Vlad Florea. "Expiry date recognition using deep neural networks." International Joural of User-System Interaction 13, no. 1 (2020): 1–17. http://dx.doi.org/10.37789/ijusi.2020.13.1.1.

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This paper proposes a deep learning solution for optical character recognition, specifically tuned to detect expiration dates that are printed on the packaging of food items. This method can be used to reduce food waste, having a significant impact on the design of smart refrigerators and can prove especially useful for persons with vision difficulties, by combining it with a speech synthesis engine. The main problem in designing an efficient solution for expiry date recognition is the lack of a large enough dataset to train deep neural networks. To tackle this issue, we propose to use an additional dataset composed of synthetically generated images. Both the synthetic and real image datasets are detailed in the paper and we show that the proposed method offers a 9.4% accuracy improvement over using real images alone.
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Santoso, Atikah Yuniar, and Nenden Kostini. "Perancangan Sistem Informasi Inventori untuk Pengecekan Expired Date pada Divisi Baby PT. Aeon Indonesia Cabang Jakarta Garden City." Jurnal Indonesia : Manajemen Informatika dan Komunikasi 5, no. 1 (2024): 913–27. http://dx.doi.org/10.35870/jimik.v5i1.571.

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The inventory information system for checking expired dates is a computer-based system designed to manage expired dates, aiming to facilitate better control of product expiry within the sales. PT AEON Indonesia, a retail company with multiple divisions, includes the Baby division, specializing in various baby necessities and equipment. Among the many products sold in the Baby division, some have a shelf life, yet checking their expired dates is still done manually, inspecting one item after another. This manual process has proven to be time-consuming and demands considerable human resources, potentially disrupting other retail operations. The design of an inventory information system for checking expired dates was initiated due to the weaknesses of the manual system. The research objective is to create a prototype inventory information system that employs a coloring method within a specific time range, ensuring increased effectiveness and efficiency in managing expired dates.
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Aridi, A., L. Baydoun, and C. M. S. T. Sukhn. "Challenging the Expiry Dates of Two Mycotoxins Standards: Afla and Ochra A." Journal of Materials Science and Chemical Engineering 05, no. 08 (2017): 59–68. http://dx.doi.org/10.4236/msce.2017.58006.

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Sevostyanova, E. M., O. A. Soboleva, I. L. Kovaleva, and I. N. Gribkova. "Soft drinks. Organoleptic analysis — a criterion for substantiation of expiry dates of products." Food systems 5, no. 3 (2022): 176–84. http://dx.doi.org/10.21323/2618-9771-2022-5-3-176-184.

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The paper considers the topicality of the development of methodological approaches to the method for accelerated aging of soft drinks on the market. Selection principles for the controlled indicators that essentially influence finished product quality are presented and the method for sample processing that allows modeling conditions of product spoilage is examined. The investigations enabled establishing the most important criteria (acetaldehyde content, sucrose transformation, CO2 concentration, organoleptic indicators) that allow predicting expiry dates of soft drinks by express methods. The comparative assessment of quality and safety of soft drinks in the conditions of “accelerated” and “natural” aging (over the shelf life with regard to the reserve ratio) by the selected criteria was carried out. The criteria parameters for tasting assessment of soft drinks that allow more correct assessment of nuance descriptors of a product were developed. It is shown that cyclic impact of temperature regimes (warmth 50 °C / cold 6 °C) during the exposure time of 30 days enables modeling soft drink storage over the shelf-life of 12 months in the conditions of natural aging. In this study, the expiry date was confirmed for the studied soft drinks based on plant raw materials and was established for drinks based on flavoring agents.
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Amare, Constance, Olivier Mantaux, Arnaud Gillet, Matthieu Pedros, and Eric Lacoste. "Innovative test methodology for shelf life extension of carbon fibre prepregs." IOP Conference Series: Materials Science and Engineering 1226, no. 1 (2022): 012101. http://dx.doi.org/10.1088/1757-899x/1226/1/012101.

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Abstract The aerospace industry makes extensive use of composite materials in the form of fibre fabrics pre-impregnated with thermosetting resin, called prepregs. In order to minimize the resin polymerization before curing, prepregs must be stored at -18°C (0°F). There are therefore expiration dates for prepregs before use. Although manufacturers try to minimize storage time, offcuts and time out of the freezer, it is estimated that 30% to 40% of the prepregs are not used [1]. Today, recertification of expired materials is still complex and expensive, therefore it is generally chosen to send expired prepregs to landfill. The purpose of this work is to correlate physicochemical measurements with the loss of mechanical performance in order to point out and measure the real aging effects during excessive storage time. Processability, physicochemical and mechanical tests were performed in order to understand which tests are truly representative of ageing. This study was illustrated by testing on unidirectional Hexcel carbon/epoxy prepreg. Different expiry dates of this material were studied and the properties were compared. It was shown that the main observed degradation was the processability of the prepreg while mechanical performance was minimally degraded after the expiry date. This study could lead to a simpler measurement of the actual expiry rate of prepregs, which could be useful to speed up recertification procedures or to propose new scenarios to extend the shelf-life of expired prepregs [2].
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30

McLennan, Frazer. "Considerations, concerns and recommendations in calculating patent expiry dates for United States patents." World Patent Information 37 (June 2014): 14–18. http://dx.doi.org/10.1016/j.wpi.2014.01.004.

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31

Abdulraheem, Abdulkabir, and Im Y. Jung. "Effective Digital Technology Enabling Automatic Recognition of Special-Type Marking of Expiry Dates." Sustainability 15, no. 17 (2023): 12915. http://dx.doi.org/10.3390/su151712915.

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In this study, we present a machine-learning-based approach that focuses on the automatic retrieval of engraved expiry dates. We leverage generative adversarial networks by augmenting the dataset to enhance the classifier performance and propose a suitable convolutional neural network (CNN) model for this dataset referred to herein as the CNN for engraved digit (CNN-ED) model. Our evaluation encompasses a diverse range of supervised classifiers, including classic and deep learning models. Our proposed CNN-ED model remarkably achieves an exceptional accuracy, reaching a 99.88% peak with perfect precision for all digits. Our new model outperforms other CNN-based models in accuracy and precision. This work offers valuable insights into engraved digit recognition and provides potential implications for designing more accurate and efficient recognition models in various applications.
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Sarla, Gurmeet S. "Efficacy and disposal of drugs after the expiry date." Egyptian Journal of Internal Medicine 31, no. 4 (2019): 431–34. http://dx.doi.org/10.4103/ejim.ejim_110_19.

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AbstractEvery drug manufacturer is legally bound to display the date of expiry on all pharmaceutical products. Excluding certain medicines such as nitroglycerin, insulin, epinephrine, and tetracycline, most medicines stored under reasonable conditions retain at least 70–80% of their original potency for at least 1–2 years after the expiration date, even after the container has been opened. The drug is likely to lose some potency after the expiration date, but it is not clear how much potency is lost over a certain period of time past expiration dates. Placing medication in a cool place, such as a refrigerator, will help it remain potent for many years. Even though both the American Medical Association and the Food and Drug Administration do not recommend the dosing of expired pharmaceuticals at this time, discussion of the issue is warranted in order to understand the potential behind some expired drugs. This review article studies the financial implications and reason for stock piling of unused and expired pharmaceuticals, health hazards, common and ideal ways of disposal of unused and expiry medications and the way forward.
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Venter, Pierre J., and Eben Maré. "Univariate and Multivariate GARCH Models Applied to Bitcoin Futures Option Pricing." Journal of Risk and Financial Management 14, no. 6 (2021): 261. http://dx.doi.org/10.3390/jrfm14060261.

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In this paper, the Heston–Nandi futures option pricing model is applied to Bitcoin futures options. The model prices are compared to market prices to give an indication of the pricing performance. In addition, a multivariate Bitcoin futures option pricing methodology based on a multivatiate GARCH model is developed. The empirical results show that a symmetric model is a better fit when applied to Bitcoin futures returns, and also produces more accurate option prices compared to market prices for two out of three expiry dates considered.
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Marshall, Matilda. "Matens kulturella död och återuppståndelse." Kulturella Perspektiv – Svensk etnologisk tidskrift 22, no. 2 (2013): 34–38. http://dx.doi.org/10.54807/kp.v22.27751.

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Using metaphors of death, the article explores food’s different phases of edibility in terms of perceptions and habits. Perceptions of dirt and expiry dates are cultural factors which may influence the disposal as well as ideas about potentially harmful decay, such as mould. Wasted food can be resurrected by dumpster divers performing attempts of resuscitation in supermarkets’ containers. Additionally, composting and transformation into bio-fuel can turn food waste into new and useful matter. The waste is thus is in a constant flux and incorporated into the aspiration for a sustainable society.
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Abdulraheem, Abdulkabir, and Im Y. Jung. "A Comparative Study of Engraved-Digit Data Augmentation by Generative Adversarial Networks." Sustainability 14, no. 19 (2022): 12479. http://dx.doi.org/10.3390/su141912479.

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In cases where an efficient information retrieval (IR) system retrieves information from images with engraved digits, as found on medicines, creams, ointments, and gels in squeeze tubes, the system needs to be trained on a large dataset. One of the system applications is to automatically retrieve the expiry date to ascertain the efficacy of the medicine. For expiry dates expressed in engraved digits, it is difficult to collect the digit images. In our study, we evaluated the augmentation performance for a limited, engraved-digit dataset using various generative adversarial networks (GANs). Our study contributes to the choice of an effective GAN for engraved-digit image data augmentation. We conclude that Wasserstein GAN with a gradient norm penalty (WGAN-GP) is a suitable data augmentation technique to address the challenge of producing a large, realistic, but synthetic dataset. Our results show that the stability of WGAN-GP aids in the production of high-quality data with an average Fréchet inception distance (FID) value of 1.5298 across images of 10 digits (0–9) that are nearly indistinguishable from our original dataset.
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SayedFachrurrazi, Muthamainnah, Muhammad Fajar Maulana, and Angga Pratama. "APPLICATION OF THE FIFO MODEL IN THE DRUG INVENTORY INFORMATION SYSTEM AT THE ASYFA KRUENG MANE PHARMACY." MULTICA SCIENCE AND TECHNOLOGY (MST) JOURNAL 3, no. 1 (2023): 142–46. http://dx.doi.org/10.47002/mst.v3i1.427.

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Asyfa Krueng Mane Pharmacy is a business entity engaged in the sale of drugs. The drug supply data processing system that was carried out at the Asyfa Krueng Mane Pharmacy still uses ordinary stationery to process drug supply data so that it is deemed less effective and efficient. Therefore, there is a need for an information system that can be used to assist and support the efficiency of the drug data processing process at the Asyfa Krueng Mane Pharmacy using the FEFO (First First Out) method, which is a method that dispenses drugs with shorter expiry dates than drugs with a later expiry date. long. With the application of the FEFO method in the Asyfa Krueng Mane Pharmacy information system, it is hoped that there will be no more accumulation of drugs and drugs with shorter expiration than drugs with longer expiration can be issued in order. As for the research results, you can see the Asyfa Pharmacy and type of Obt001 and type of Paracetamol and drug stock and date of entry and exit&#x0D; &#x0D; &#x0D; &#x0D;
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Abu Mhanna, Hamad Yahia, Ahmad Fairuz Omar, Yasmin Md Radzi, Hanan Fawaz Akhdar, and Haytham Al Ewaidat. "Expired EBT3 Films’ Sensitivity for the Measurement of X-ray and UV Radiation: An Optical Analysis." Materials 15, no. 8 (2022): 2903. http://dx.doi.org/10.3390/ma15082903.

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The aim of this study is to compare the optical responses of external beam therapy 3 (EBT3) films exposed to X-rays and solar ultraviolet rays (SUV-rays), as a dose control technique in the clinical sector for various radiation types, energies, and absorbed doses up to 4 Gy. In this study, EBT3 films with three different expiry dates were prepared and cut into pieces of size 2 by 2 cm2. The first group was exposed to 90 kVp X-rays, while the second group was exposed to the SUV-rays at noon. The analysis was performed using a visible Jaz spectrometer and an EPSON Perfection V370 Photo scanner to obtain the absorbance, the net reflective optical density (ROD) and the red-green-blue (RGB) values of the samples. The results have shown that spectroscopic measurements of the exposed expired EBT3 films with these radiation sources are able to produce primary peaks and secondary peaks at λ = 641.74 nm and λ = 585.98 nm for X-rays, and at λ = 637.93 nm and λ = 584.45 nm for SUV-rays, respectively. According to these findings, compared to 2021 films that expired shortly before the trial start date; 2018 films responded better to the absorbed dose than 2016 films when exposed to both X-ray and SUV-rays. In terms of energy dependence, the expired EBT3 2018 had the largest net ROD value. Using L*a*b* indices extracted from the RGB data, and despite that EBT3 films have expiry dates according to the manufacturer; all the films exhibited a substantial colour change, indicating that these films are still usable for clinical and research purposes.
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Shapovalova, L. A., M. V. Fedotova, and V. A. Mukhin. "Justification for requirements applicable to updating the standard for canned fish liver, caviar and milt «Po-Murmanski» in order to enhance products’ competitiveness." Trudy VNIRO 192 (August 15, 2023): 172–80. http://dx.doi.org/10.36038/2307-3497-2023-192-172-180.

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This aims to justify the requirements for updating the current national standard GOST R56418–2015 «Cannedfish liver, caviar and milt «Po-Murmanski». Specifications», taking into consideration the results from qualitymeasurements of canned fresh minced cod liver. Research methods: Sensory analysis of food and the titrimetric method with visible indication was applied. This paper summarizes the results from measurements of the fat acidity value in canned food that was made in compliance with GOST R56418–2015 in marine environments from 2016 to 2021. We made an assessment to justify the expiry dates and storage requirements for canned food under the two temperature conditions. The paper defines the main provisions of the standard that require updating. Results: This paper proves the practicability of updating the standard GOST R56418–2015 by such ways as follows: changing the expiry dates of canned cod (haddock) liver «Po-Murmanski» under different storage conditions, applying the standard instrumental procedure to estimate the fat acidity value, using a geographical indication in labeling as a modern way of product differentiation. The paper shows dynamics in the fat acidity value during the storage of canned food made of fresh minced cod liver under the two temperature conditions. The paper demonstrates correlations between the fat acidity value and the organoleptic properties of canned food that was made of fresh and frozen fish in compliance with the existing various reference documents on standardization. Practical relevance: The results from this study will be used to update GOST R56418–2015. After public discussions and approval under the established procedure, the updated national standard will be demanded by factories and companies.
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39

Hyong-Chol O, Yong-Gon Kim, and Dong-Hyok Kim. "Higher order binaries with time dependent coefficients and two factors - model for defaultable bond with discrete default information." Malaya Journal of Matematik 2, no. 04 (2014): 330–44. http://dx.doi.org/10.26637/mjm204/001.

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In this article, we consider a 2 factors-model for pricing defaultable bonds with discrete default intensity and barrier where the 2 factors are a stochastic risk free short rate process and firm value process. We assume that the default event occurs in an expected manner when the firm value reaches a given default barrier at predetermined discrete announcing dates or in an unexpected manner at the first jump time of a Poisson process with given default intensity given by a step function of time variable. Then our pricing model isgiven by a solving problem of several linear PDEs with variable coefficients and terminal value of binary type in every subinterval between the two adjacent announcing dates. Our main approach is to use higher order binaries. We first provide the pricing formulae of higher order binaries with time dependent coefficients and consider their integrals on the last expiry date variable. Then using the pricing formulae of higher binary options and their integrals, we give the pricing formulae of defaultable bonds in both cases of exogenous andendogenous default recoveries and perform credit spread analysis.
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40

Weerasooriya, Trewon, and Kishore Kumar. "Foodligence – Predicting Expiry Date of Perishable Foods to Reduce Loss and Waste." Computer Science & Engineering: An International Journal 12, no. 6 (2022): 155–64. http://dx.doi.org/10.5121/cseij.2022.12615.

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“Food loss and waste” is a growing issue for the environment, the economy, and society worldwide. It has an adverse effect on social, environmental, and economic issues. Poor planning, excessive production, and customer perception are the main causes of food loss and waste. Inefficient use of perishables before to expiration is another significant contributor to food loss and waste. The study primarily concentrates on Sri Lanka's hotels and restaurants, one of the two main sub-sectors of the hospitality and food services business. To reduce food loss and waste during the processes of the food supply chain of hotels and restaurants, the research suggests an expiry predictor for perishable food items using artificial intelligence. It also suggests a donation platform to distribute any surplus or unconsumed perishables to the needy/beneficiaries. The predictor enables hotels and restaurants to be aware of the best dates to use the perishables they have purchased, while if any are left over or spoil, they can be listed using the freshness index so that people in need can request them and make purchases for a price range the hotels and restaurants have specified. The solution aims to reduce waste in the food supply chain and control it to the greatest extent feasible.
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41

Zilker, Markus, Fritz Sörgel, and Ulrike Holzgrabe. "A systematic review of the stability of finished pharmaceutical products and drug substances beyond their labeled expiry dates." Journal of Pharmaceutical and Biomedical Analysis 166 (March 2019): 222–35. http://dx.doi.org/10.1016/j.jpba.2019.01.016.

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42

Hachemi, Khalid, and Béatrix Besombes. "Integration of products expiry dates in optimal scheduling of storage/retrieval operations for a flow-rack AS/RS." International Journal of Industrial and Systems Engineering 15, no. 2 (2013): 216. http://dx.doi.org/10.1504/ijise.2013.056097.

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43

Jani, Mrudul Y., Manish R. Betheja, Urmila Chaudhari, and Biswajit Sarkar. "Effect of Future Price Increase for Products with Expiry Dates and Price-Sensitive Demand under Different Payment Policies." Mathematics 11, no. 2 (2023): 263. http://dx.doi.org/10.3390/math11020263.

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The current study works with an inventory management strategy under the discount cash flow approach for perishable commodities with expiry dates, price-sensitive demand, and investment in preservation technology. In addition, this study examines the probable influence of price-increase on the replenishment strategy of the retailer where specific delivery units can be purchased. Furthermore, in this model, two circumstances are deliberated: (I) when the time of the specific delivery matches with the reordering time of the retailer or (II) when the time of the specific delivery emerges within the duration of the sale. Before the price increase, the supplier provides two payment policies to the retailer from which they can choose one. The policies are either: (1) a permissible delay in payment on regular orders or (2) a discount in payment for the specific delivery. The key goal is to optimize the overall profit for the retailer with respect to the sales price, investment in preservation technology, and cycle time during the depletion time of the specific delivery. In addition, an algorithm is created to optimize the results and seven numerical illustrations are discussed to explain the results along with the special case. Finally, to display the pertinence of this model, a sensitivity analysis of the main parameters is performed with important managerial implications. The key findings of this research are (1) before the price increase, the retailer gets the maximum profit if the retailer chooses a discount in payment policy on the specific delivery; (2) how much to order from the supplier and when to place a specific delivery to generate a maximum profit; and (3) the price-sensitive demand and assumption of future price increase negatively affect the retailer’s overall profit, and the retailer gets maximum benefits if the retailer initially orders the maximum number of units from the supplier before the price increase.
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44

Puranik, M., P. G. Yeole, and S. J. Wadher. "FORCED DEGRADATION STUDY OF POST-SHELF LIFE AND MARKETED TABLETS OF AMLODIPINE BY RP-HPLC." INDIAN DRUGS 52, no. 02 (2015): 34–39. http://dx.doi.org/10.53879/id.52.02.10251.

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The stability of pharmaceutical products plays an important role from the economical point of view. There are not many studies that report about the stability of drugs past their expiration dates. The objective of the current study was to determine tablet content and perform dissolution test of expired tablets of amlodipine besylate and tablets where expiry date has not exceeded and to develop simple, accurate, sensitive and stability indicating RP-HPLC method for the determination of per cent drug remained of Amlodipine besylate in the presence of its degradation products in bulk drug, expired tablets and tablets whose expiry date has not been exceeded. Drug was subjected to all stress conditions such as hydrolysis (acidic and alkaline), oxidation (3% H2O2 v/v), photolysis, thermal degradation and humidity study. Content determination was performed using spectrophotometric and RP-HPLC method; the per cent of dissolved substance from tablets during dissolution test was performed using spectrophotometric method and detection was made at 239 nm. All stressed samples were successfully analysed on C18 column using mobile phase phosphate buffer pH 3.5 (50mM): methanol: acetonitrile in the ratio of 30:60:10 v/v/v. A flow rate was maintained at 1.5 ml/min and detection was made at 240 nm. The proposed methods were validated with regard to linearity, sensitivity, and intermediate accuracy and precision. No discrepancies between the results of determination and the declared values range for all the analysed tablets were observed. The results of performed study might suggest that storage of analysed batches of tablets over time period exceeding the expiry date given by the manufacturer did not influence their contents.
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45

Secondi, Luca. "Expiry Dates, Consumer Behavior, and Food Waste: How Would Italian Consumers React If There Were No Longer “Best Before” Labels?" Sustainability 11, no. 23 (2019): 6821. http://dx.doi.org/10.3390/su11236821.

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Much research has been carried out on food losses and waste in the various stages of the food supply chain, consolidating the “fight” against food waste as one of the most important challenges in industrialized countries. Numerous different studies have focused on food waste at the household level, identifying both the multiple causes linked to this behavior and the factors that can drive towards the reduction of food waste. In this paper, a different approach was used, trying to analyze different individuals’ reactions to a concrete action consisting of removing “best before” labels from some food products, following the recent proposal by European Union to simplify date marking. How could any action in this area be implemented in every single country? Bearing in mind the general results of the cross-sectional official survey Flash Eurobarometer n. 425, the purpose of this study was to go deeper into the study of how consumers would behave if the expiry date were no longer available on a pack of spaghetti. The heterogeneity observed in the possible alternative reactions across European Union 28 countries, as well as by considering the importance played by the local context in which individuals reside led us to focus on a single country, and specifically on the Italian context, as an example of country in which citizens have a higher average level of knowledge about expiration dates than the global EU28 citizens, but where, at the same time, there is a more conservative behavior regarding using a product with no expiry date. The multinomial regression model—estimated using the generalized maximum entropy estimator—enabled us to identify different profiles and groups of individuals with which—as a suggestion to policy makers—it would be first necessary to intervene in order to standardize the level of knowledge on this specific topic. In this direction, territorial macro-areas proved to be strongly associated with the various reactions; the probability of consuming or throwing away was found to significantly differ across all the studied regional macro-areas, with a higher likelihood of throwing away the product with no best-before date in southern regions.
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46

Lee, Sohee, Nakyeong Kim, Sung-Byung Yang, and Sang-Hyeak Yoon. "Analysis of consumer responses to labeling methods for expiry and consumable dates by food type: A scenario-based experiment." Journal of Korea Service Management Society 23, no. 4 (2022): 109–31. http://dx.doi.org/10.15706/jksms.2022.23.4.005.

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Tromp, Seth-Oscar, Hajo Rijgersberg, Fátima Pereira da Silva, and Paul Bartels. "Retail benefits of dynamic expiry dates—Simulating opportunity losses due to product loss, discount policy and out of stock." International Journal of Production Economics 139, no. 1 (2012): 14–21. http://dx.doi.org/10.1016/j.ijpe.2011.04.029.

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48

Naresh, Kumar Naresh Kumar. "BEST PRICING AND ORDERING POLICY FOR DETERIORATING OR DECAYING ITEMS WITH MAXIMUM LIFESPAN UNDER ACCEPTABLE DELAYS IN PAYMENTS." Advances and Applications in Mathematical Sciences 21, no. 7 (2022): 4069–81. https://doi.org/10.5281/zenodo.14884113.

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The products like fruits, vegetables, medicines, etc. not only deteriorate or decay&nbsp;continuously as a result of obsolescence, Evaporation, malfunction, etc. But they also have&nbsp;expiry dates. Numerous researchers have studied Economic Order Quantity (EOQ) inventory&nbsp;models for perishable goods, but few of them have considered the maximum life expectancy of&nbsp;deteriorating items. In this paper, an EOQ inventory model is formulated to maximize the&nbsp;salesman&rsquo;s profit. We have taken the products which deteriorate or decay continuously and have&nbsp;a maximum life. In addition, the salesman is allowed an acceptable delay in payments to settle&nbsp;the account. Mathematical formulation of the model is clarified through numerical examples.&nbsp;Finally, the sensitivity investigation is performed with respect to different parameters.
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Izzati, Inaya, and Dida Diah Damayanti. "Development of Inventory Model to Reduce Total Inventory Costs at RSUD Mentawai." International Journal of Innovation in Enterprise System 7, no. 02 (2023): 190–200. http://dx.doi.org/10.25124/ijies.v7i02.241.

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The inventory policy problem is a problem in the inventory system related to how to ensure that each usage demand can be met at minimal cost. In the healthcare industry, it is imperative that the procurement and use of stock is not only cost-effective, but also that the required stock is always available. Discrepancies between total inventory and usage can lead to damage to BMHP inventory as the items have expiry dates, as well as excess total inventory costs. The problem of total inventory costs exceeding the budget occurs because overstock is 83% of the total need, overstock is caused by an excessive number of drug orders purchased. The purpose of this study is to reduce the total cost of inventory by considering expiry costs, inspection cost, shortage cost, order cost, holding cost using the EOQ method. The first stage in this study is to calculate the optimal order quantity value, then find the expected number of drug expirations. These results will be used to calculate the total inventory cost of five types of medical materials. for the inspection cost value, if the number of expired medical materials is above 20, the inspection cost value is not equal to zero. The calculation results found that the total inventory cost was Rp. 162,904,965, this cost is less than the actual cost of Rp. 185,843,346.00 with a difference of 12%.
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De Paula Miranda, Fernanda Maria, Mariana de Lourdes Almeida Vieira, and Patrícia Sueli Rezende. "Determination of Lead and Evaluation of Microbial Contamination in Eye Shadows and Lipsticks Samples." Ensaios e Ciência C Biológicas Agrárias e da Saúde 26, no. 1 (2022): 87–96. http://dx.doi.org/10.17921/1415-6938.2022v26n1p87-96.

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Este trabalho avaliou a qualidade de sombras e batons novos, usados, vencidos e válidos, doados por consumidores e adquiridos no Brasil. Testes microbiológicos foram realizados para avaliar a presença dos microrganismos patógenos Pseudomonas aeruginosa, Staphylococcus aureus e Escherichia coli e a contagem de mesófilos aeróbios totais. Para quantificar o chumbo, as amostras foram submetidas à digestão ácida. Após o preparo, as amostras foram analisadas em condições otimizadas e validadas por GF AAS. Os planejamentos experimentais empregados para otimização do método foram: Planejamento Fatorial Completo 2³ e CCD. Das 25 amostras analisadas, 18 (75%) podem ser consideradas reprovadas segundo os limites microbianos estabelecidos pela legislação sanitária brasileira. Dentre as amostras de sombras reprovadas, todas eram usadas, quatro estavam com prazos de validade expirados, três não apresentavam validade na embalagem primária; dentre os batons reprovados que eram usados, cinco estavam com prazos de validade expirados, quatro não apresentavam validade na embalagem primária e um era válido; um batom reprovado era novo e válido. Nossos dados mostram a importância do consumidor utilizar e armazenar os produtos em condições adequadas, para evitar a contaminação microbiana. As concentrações de chumbo obtidas nos batons variaram de 0,45 ± 0,08 mg kg-1 a 6,8 ± 0,2 mg kg-1, e nas sombras de &lt;LOD a 6,2 ± 0,4 mg kg-1, sendo que todas abaixo do nível máximo para Pb. Observou-se que, em geral, as amostras de sombras apresentaram maiores concentrações de chumbo do que os batons e que os produtos de uso infantil apresentaram menor concentração desse metal. Palavras-chave: Batons. Sombra para Olhos. Chumbo. Avaliação Microbiana. Abstract This work evaluated the quality of new, used, expired and valid samples of eye shadows and lipsticks donated by consumers and purchased in Brazil. Microbiological tests were performed to evaluate the presence of the pathogenic microorganisms Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli and the counts of total aerobic mesophilic microorganisms. In order to quantify lead, samples were submitted to the acid digestion in a block digester. The samples were analyzed under optimized and validated conditions by GF AAS. A 23 Factorial Design and CCD were employed to method optimization. Considering the 25 analyzed samples, 75% can be considered reproved according to the microbial limits established by Brazilian sanitary law. Among reproved eye shadows, all were used, 4 were out of their expiry dates and 3 were had no expiry date indicated on their primary packaging. Among reproved lipsticks that were used, 5 were out of their expiry dates, 4 had no expiry date indicated on their primary packaging and 1 was not expired; one of the reproved lipsticks was new and non-expired. Our data show the importance of using and storing this type of products under appropriate conditions. Lead concentrations found in lipsticks varied from 0.45 ± 0.08 mg kg-1 to 6.8 ± 0.2 mg kg-1, and in eye shadows from &lt;LOD to 6.2 ± 0.4 mg kg-1, being all samples below to the maximum level. In general, eye shadows samples presented higher lead concentrations than to lipsticks and that child use products presented less concentration of this metal. Keywords: Lipsticks. Eye Shadows. Lead. Microbial Evaluation.
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