Relevant bibliographies by topics / Furo[2

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Furo[2'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Furo[2"

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Sleziak, Róbert, Slávka Balážiová, and Alžbeta Krutošíková. "Reactions of Furo[2,3-b]pyrrole and Furo[3,2-b]pyrrole-Type Aldehydes." Collection of Czechoslovak Chemical Communications 64, no. 7 (1999): 1135–46. http://dx.doi.org/10.1135/cccc19991135.

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The synthesis of methyl 2-formyl-6-(methoxymethyl)furo[2,3-b]pyrrole-5-carboxylate (1d) is described. The reactions of methyl 2-formylfuro[2,3-b]pyrrole-5-carboxylates 1a-1d with malononitrile afforded methyl 2-(2,2-dicyanovinyl)furo[2,3-b]pyrrole-5-carboxylates 3a-3d, with methyl cyanoacetate methyl 2-[2-cyano-2-(methoxycarbonyl)vinyl]furo[2,3-b]pyrrole-5-carboxylates 4a-4d and with 2-furylacetonitrile methyl 2-[2-cyano-2-(2-furyl)vinyl]furo[2,3-b]pyrrole-5-carboxylates 5a-5d. Compounds 1b-1d and methyl azidoacetate gave the appropriate vinylazides 6b-6d, which were used for preparation of su
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Zemanová, Ivana, and Renata Gašparová. "SYNTHESIS AND REACTIONS OF NEW DERIVATIVES OF FURO[3,2-b]PYRROLE." Nova Biotechnologica et Chimica 12, no. 2 (2013): 100–107. http://dx.doi.org/10.2478/nbec-2013-0012.

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Abstract Synthesis of methyl 4H-furo[3,2-b]pyrrole-5-carboxylate is taken place in two step synthesis. Vilsmeier-Haack reaction of 4H-furo[3,2-b]pyrrole-5-carboxylate 1 led to methyl 2-formyl-4H-furo[3,2- b]pyrrole-5-carboxylate 4, which served as starting compound for synthesis of furo[3,2-b]pyrrole-2- aldoxime 5 and methyl 2-[(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-4H-furo[3,2-b]pyrrole-5- carboxylate 7. The hydrazinolysis of 1 was prepared by carbohydrazide 2, which subsequently reacted with aldehydes to form of derivatives 3. Pyrazole derivatives 11 were prepared by the reaction
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El-Shahawi, Manal M., and Ahmed K. El-Ziaty. "Enaminonitrile as Building Block in Heterocyclic Synthesis: Synthesis of Novel 4H-Furo[2,3-d][1,3]oxazin-4-one and Furo[2,3-d]pyrimidin-4(3H)-one Derivatives." Journal of Chemistry 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/5610707.

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2-Amino-4,5-diphenylfuran-3-carbonitrile 1 was utilized as building block for the construction of new furo[2,3-d]pyrimidin-4(3H)-one derivative 2 and 4H-furo[2,3-d][1,3]oxazin-4-one derivative 3 via treatment with acetic anhydride and benzoyl chloride, respectively. The 4H-furo[2,3-d][1,3]oxazin-4-one derivative 3 was transformed into novel furo[2,3-d]pyrimidin-4(3H)-ones 4–8, tetrazolylfuran derivative 10, and furo[3,2-d]imadazolone derivative 11 via reaction with various nitrogen nucleophiles. The structure features of the synthesized compounds were established from their spectral and elemen
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Abu-Hashem, Ameen. "Synthesis of New Furothiazolo Pyrimido Quinazolinones from Visnagenone or Khellinone and Antimicrobial Activity." Molecules 23, no. 11 (2018): 2793. http://dx.doi.org/10.3390/molecules23112793.

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Substituted-6-methyl-1-thioxo-1,2-dihydro-3H-furo[3,2-g]pyrimido[1,6-a]quinazolin-3-ones (5a,b) were synthesized from condensation of visnagenone (2a) or khellinone (2b) with 6-amino-thiouracil (3) in dimethylformamide or refluxing of (4a) or (4b) in dimethylformamide. Hence, compounds (5a,b) were used as the starting materials for preparing many new heterocyclic compounds such as; furo[3,2-g]pyrimido[1,6-a]quinazoline (6a,b), furo[3,2-g]thiazolo[2′,3′:2,3]pyrimido[1,6-a]quinazolinone (7a,b), substituted-benzylidene-furo[3,2-g]thiazolo[2′,3′:2,3]pyrimido[1,6-a]quinazoline-3,5-dione (8a–f), 3-o
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Janeba, Zlatko, Noha Maklad, and Morris J. Robins. "Synthesis of 6-(alkoxymethyl)- and 6-(alkylsulfanylmethyl)furo[2,3-d]pyrimidin-2(3H)-one analogues." Canadian Journal of Chemistry 84, no. 4 (2006): 561–68. http://dx.doi.org/10.1139/v06-042.

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Treatment of 6-(hydroxymethyl)furo[2,3-d]pyrimidin-2(3H)-one (2) with 1-iodoalkanes and potassium carbonate resulted in predominant formation of N3 (and minor amounts of O2) alkylated regioisomers. Treatment of the 3-alkyl products (3) with thionyl chloride gave highly reactive 6-chloromethyl intermediates (5). Direct solvolysis of 5 in alcohol solutions (~50 °C) produced 3-alkyl-6-(alkoxymethyl)furopyrimidin-2(3H)-ones (6), whereas extensive decomposition of 5 occurred with added base promoters. Sonication of 5 with sodium thioacetate in acetonitrile gave the air-stable 6-(alkylsulfanylmethyl
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A.AlOmari, Nohad, Adnan O. Omar, and Iklas M. Taher. "Preliminary Cytotoxic Study of Some Novel Furo-2-quinolone Compounds." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 18, Suppl. (2017): 32–38. http://dx.doi.org/10.31351/vol18isssuppl.pp32-38.

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In this research, new series of Furo-2-quinolone [FQ] compounds have been synthesized. These novel [FQ] compounds were prepared from coumarin derivatives (Furocoumarins: psoralen and isopsoralen).Identifications of these FQ compounds were performed by using infrared spectrum (I.R), Ultraviolet spectrum (U.V) and Nuclear Magnetic Resonance spectrum (H1-NMR) besides some physical data. The cytotoxic screening involves ;using HEP-2 cell line which gave differential responses against tested compounds : 4,6 Dimethyl furo[2, 3-g] coumarin (C1), 1-(2`, 4`, Dimethoxy benzylideneimino)-2,6-dimethyl Fur
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Shiotani, Shunsaku. "Furopyridines.XIV. Synthesis of 2-aminoalkyl derivatives of furo[2,3-b]-, furo[3,2-b], furo[2,3-c]- and furo[3,2-c]pyridine." Journal of Heterocyclic Chemistry 30, no. 4 (1993): 1035–39. http://dx.doi.org/10.1002/jhet.5570300432.

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Cho, Young K., Michael E. Smith, and Ralph Norgren. "Low-dose furosemide modulates taste responses in the nucleus of the solitary tract of the rat." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 287, no. 4 (2004): R706—R714. http://dx.doi.org/10.1152/ajpregu.00090.2004.

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Taste-evoked neural responses in the nucleus of the solitary tract (NST) are subject to both excitatory and inhibitory modulation by physiological conditions that influence ingestion. Treatments that induce sodium appetite predominantly reduce NST gustatory responsiveness to sapid stimuli. When sodium appetite is aroused with 10 mg of the diuretic furosemide (Furo), however, NST gustatory neurons exhibit an enhanced responsiveness to NaCl. In addition to inducing a sodium appetite, 10 mg Furo supports a conditioned taste aversion (CTA). A lower, 2-mg dose of Furo induces an equivalent sodium a
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K., C. MAJUMDAR, and DAS U. "Studies on Sigmatropic Rearrangements : Regioselective Synthesis of Coumarins, Quinolones and Thiocoumarins with 3,4-Fused Pyran or Furan Ring Systems by Claisen Rearrangement." Journal of Indian Chemical Society Vol. 74, Nov-Dec 1997 (1997): 884–90. https://doi.org/10.5281/zenodo.5900433.

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Department of Chemistry, University of Kalyam, Kalyana-741 235 <em>Manuscript received 4 September 1997</em> A brief review of the regioselective synthesis of pyrano[3,2-<em>c</em>][1]benzopyran-5(2<em>H</em>)-ones, pyrano[3,2-<em>c</em>][1]benzothiapyran-5(2<em>H</em>)-one, pyrano[3,2-<em>c</em>]quinolin-5(2<em>H</em>)-ones, pyrano(2,3-<em>c</em>)[1]benzopyran-5(3<em>H</em>)-ones, 3<em>H</em>-pyrano[2,3-<em>c</em>)quinolin-5(6H)-ones, thiapyrano(2, 3- b) (1)benzothiapyran-5(2<em>H</em>)-ones, thiapyrano[2,3-<em>b]</em>&nbsp;[1]benzopyran-5(2<em>H</em>)-ones, furo[3,2-<em>c</em>] [1] benzopyra
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Sirakanyan, Spinelli, Geronikaki, et al. "Synthesis, Antitumor Activity, and Docking Analysis of New Pyrido[3’,2’:4,5]furo(thieno)[3,2-d]pyrimidin-8-amines." Molecules 24, no. 21 (2019): 3952. http://dx.doi.org/10.3390/molecules24213952.

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Continuing our research in the field of new heterocyclic compounds, herein we report on the synthesis and antitumor activity of new amino derivatives of pyrido[3’,2’:4,5](furo)thieno[3,2-d]pyrimidines as well as of two new heterocyclic systems: furo[2–e]imidazo[1,2-c]pyrimidine and furo[2,3-e]pyrimido[1,2-c]pyrimidine. Thus, by refluxing the 8-chloro derivatives of pyrido[3’,2’:4,5]thieno(furo)[3,2-d]pyrimidines with various amines, the relevant pyrido[3’,2’:4,5]thieno(furo)[3,2-d]pyrimidin-8-amines were obtained. Further, the cyclization of some amines under the action of phosphorus oxychlori
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Dissertations / Theses on the topic "Furo[2"

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Vaitiulionytė, Diana. "Furo[2,3-d]pirimidinų sintezė ir savybės." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2006. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2006~D_20060613_174528-81935.

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We report herein on the results of N- and O-alkylation of 5-cyano-2-methylsulfanyl-4(3H)- pyrimidinone with 4-substituted ω-bromoacetophenones. Synthesized N-(phenacyl)-4- pyrimidinones and 4-(phenacyloxy)pyrimidines with suitable substituents in pyrimidine ring are versatile synthons for the preparation of fused pyrimidine heterocycles. Chemical properties of new furo[2,3-d]pyrimidines were investigated. The structure of synthesized compounds was confirmed by data of 1H NMR, IR and UV spectra.
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Wang, Yu-Pu Ph D. Massachusetts Institute of Technology. "I. [2 +2] Cycloaddition and benzannulation of 2-iodoynamides and application to the construction of highly substituted indoles : II. Synthesis of furo[2,3-g]thieno[2,3-e]indole via a benzannulation strategy." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/101556.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemistry, 2015.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>The synthesis and reactions of 2-iodoynamides were investigated. 2-Iodoynamides undergo efficient and regioselective [2 + 2] cycloaddition with ketene to produce cyclobutenones that are useful synthetic building blocks. Reaction of 2-iodoynamides and vinylketenes generated in situ from cyclobutenones proceeds via a pericyclic cascade mechanism to produce highly substituted 2-iodoanilines. Tandem strategies for the synthesis of
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Perry, Philip J. "Synthesis and biological evaluation of novel cytotoxic heterocylic compounds : furo[2,3-b]naphthoquinones and 2-aryl-4H-3,1-benzoxazin-4-ones." Thesis, De Montfort University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391202.

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Mauz, Tobias. "4-Hydrazono-1,3-oxazolidin-2-one 1,3,4-Oxadiazin-2-one und Furo[3,4-d]-pyrimidin-2,4,5-trione als Leitstrukturen neuer antimikrobieller Wirkstoffe Synthese, Analytik und Bestimmung der biologischen Aktivität /." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971369089.

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Thibault, Charles. "Utilisation de la chimie ''click'' Diels-Alder pour la construction d'hétérocycles oxygénés bioactifs; synthèse d'anhydrides maléiques, de cadiolides, de furo[2,3-b]chromones et découverte inusitée du réarrangement des 3-acyl-2-alkoxyfuranes." Doctoral thesis, Université Laval, 2018. http://hdl.handle.net/20.500.11794/35274.

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Les travaux présentés dans cette thèse concernent l'utilisation de la chimie ''click'' Diels-Alder pour la construction d'hétérocycles oxygénés bioactifs. Dans un premier temps, une nouvelle méthodologie de synthèse versatile menant à des anhydrides maléiques disubstitués est illustrée par la synthèse de l'anhydride chaetomélique A (2.31a, inhibiteur nanomolaire de la FTase) ainsi que la synthèse d'un agent inducteur de la germination (1.26) et d'un nouveau bis-anhydride (1.27) utilisé comme agent de réticulation pour la fixation de cellules ou de tissus. En débutant avec des alcynes commerci
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Jacquelin, Jean-Marie. "Fonctionnalisation par métallation d'amino et d'hydroxy quinoléines : applications à la synthèse de furo quinoléines." Rouen, 1987. http://www.theses.fr/1987ROUES033.

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L'amino-2 quinoléine est fonctionnalisée par métallation en position 3. Les amino-3 et -4 quinoléines ont également été métallées respectivement sur les sommets 2 et 8 mais n'ont pu être fonctionnalisées par des électrophiles carbonés. Les hydroxy-2, -3 et -4 quinoléines masquées sous forme de carbamates sont lithiés régiosélectivement sur les carbones 3, 4 et 3 respectivement. Les dérivés ortho substitués préparés par réaction d'aldéhydes sur les intermédiaires lithiés sont utilisés pour la synthèse de furo-quinoléines
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Chi, Hung Nguyen. "Synthèse et étude de nouveaux analogues tetracycliques et tricycliques des ellipticines et aza-9 ellipticines." Paris 11, 1985. http://www.theses.fr/1985PA112290.

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La présente thèse concerne la synthèse de nouveaux analogues tétracycliques et tricycliques des Ellipticines et aza-9 Ellipticines, ainsi que l'étude de L'étude de leurs propriétés biologiques. L’étude de la lithiation des furo-et pyrrolo [3,2-c] pyridines présentée dans le premier chapitre montre que l'échange avec le ter. Butyl lithium s'effectue sur le sommet 2 de ces hétérocycles. Cela permet d'accéder à divers dérivés fonctionnalisés sur leur sommet 2 à partir desquels nous avons pu accéder d'une part à des pyrido [4,3-b] benzo [f] indoles et d'autre part à des pyrido [3',4': 4,5] pyrrolo
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Silva, Orivaldo Lopes da. "Incorporação de cálcio iônico em células ósseas induzida por campo elétrico." Universidade de São Paulo, 1995. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-10062014-163725/.

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Acredita-se que sinais elétricos endógenos afetem remodelamento, metabolismo, reparo e crescimento ósseos. Existe uma ampla literatura que trata do efeito de sinais elétricos externos sobre as respostas de síntese, mitogênese e proliferação em osteoblastos e células ósseas in vitro. Acredita-se que as respostas fisiológicas ao estimulo elétrico sejam devidas a mecanismos celulares que envolvem variações na concentração citosólica de cálcio. No presente estudo esse efeito celular foi observado através da estimulação direta, por campo elétrico de intensidade fisiologicamente significativa de 10m
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Pizzuti, Lucas. "Síntese de 4-(fur-2-il)- e 4-(tien-2-il)-pirimidinas a partir de β-Alcoxivinil trifluormetil cetonas". Universidade Federal de Santa Maria, 2005. http://repositorio.ufsm.br/handle/1/10401.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>The cyclocondensation of the 1,1,1-trifluoro-4-methoxy-4-(2-heteroaryl)-3-buten-2-ones (heteroaryl = furyl and thienyl) with urea and amidines (acetamidine, benzamidine, guanidine, 1H-pyrazole-1-carboxamidine and 2-methyl-2-thiopseudourea) for synthesis of two 4-(2-heteroaryl)-6-trifluoromethylpyrimidinones and a series of ten 4-(2-heteroaryl)-6-trifluoromethylpyrimidines is reported. The reaction of the 1,1,1-trifluoro-4-methoxy-4-(2-heteroaryl)-3-buten-2-ones with urea was carried out in the presence of boron trifluoride ethera
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Hadrovic, Banina. "A study of TRPV1 and TRPV4 ion channels in the beta cells by using fura-2 based microfluorometry." Thesis, Mälardalen University, School of Sustainable Development of Society and Technology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-7350.

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<p>The calcium ion (Ca<sup>2+</sup>) is an important ion that regulates many cellular functions including exocytosis, contraction of muscles, neural functions, fertilization and cell division. In the plasma membrane of cells there are different Ca<sup>2+</sup> channels, including the transient receptor potential (TRP) family of cation channels. The TRP channels are activated by physical stimuli like temperature, stretch, osmolality, and also various ligands. These channels are divided into seven subfamilies, namely TRPC, TRPV, TRPM, TRPML, TRPA, TRPP, and TRPN.</p><p> </p><p>TRP channels can r
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Books on the topic "Furo[2"

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Perry, Philip J. Synthesis and biological evaluation of novel cytotoxic heterocyclic compounds: Furo (2,3-b) naphthoquinones and 2-aryl-4H-3,1-benzoxazin-4-ones. De Montfort University, 1996.

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Fury Book #2/blood Ra (Fury Book, No. 2). Berkley, 1992.

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Lonewolf, John. Shadow's Fury 2: Ragnarok. Independently Published, 2018.

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Furī na 2-ri. Sonī Magajinzu, 2006.

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ATV Offroad Fury 2. Prima Games, 2002.

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Williams, Rob. Miss Fury Volume 2. Dynamite Entertainment, 2016.

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Ottley, Paul G. Feathers and Furs 2. UK Book Publishing, 2021.

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Tarrow, Trinity. Fury Unleashed: Fury and Fate Series Book 2. Independently Published, 2018.

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Wedemeyer, Erin. Vow to Fury (ed 2). Wedemeyer, Erin, 2020.

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Wedemeyer, Erin. Vow to Fury (ed 2). Wedemeyer, Erin, 2020.

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Book chapters on the topic "Furo[2"

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Kodadi, Shirish Kumar, and Parthasarathy Tigulla. "In Silico Studies of Charge Transfer Complexes of 6-(Trifluoromethyl)furo[2,3-b]pyridine-2-carbohydrazides with Iodine as σ-Acceptor." In Cognitive Informatics and Soft Computing. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-0617-4_71.

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Gangjee, A., J. Yang, J. J. McGuire, and R. L. Kisliuk. "Effect of Bridge Truncation of Classical 2,4-Diamino-5-Substituted Furo [2,3-d] Pyrimidine and 2-Amino-4-Oxo-6-Substituted Pyrrolo [2,3-d] Pyrimidine on Antifolate Activity." In Chemistry and Biology of Pteridines and Folates. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0945-5_75.

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Hirota, E., K. Kuchitsu, T. Steimle, J. Vogt, and N. Vogt. "222 C14H8O6 8b,8c-Dihydro-8b,8c-dimethyl-1H,3H,5H,7H-furo[3'',4'':1',3']cyclopropa[1',2',3':3,4]pentaleno[1,6-cd]pyran-1,3,5,7-tetrone." In Molecules Containing Three or Four Carbon Atoms and Molecules Containing Five or More Carbon Atoms. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-41504-3_353.

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Grouselle, M., and D. Georgescauld. "Fura-2 Imaging of Intracellular Free Calcium Dynamics in Excitable Cells." In Water and Ions in Biomolecular Systems. Birkhäuser Basel, 1990. http://dx.doi.org/10.1007/978-3-0348-7253-9_23.

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Patel, Anish, Robert A. Hirst, Charlotte Harrison, Kazuyoshi Hirota, and David G. Lambert. "Measurement of [Ca2+]i in Whole Cell Suspensions Using Fura-2." In Methods in Molecular Biology. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-086-1_2.

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Xu, Yan-Jun, Qiming Shao, and Naranjan S. Dhalla. "Fura-2 fluorescent technique for the assessment of Ca2+ homeostasis in cardiomyocytes." In Novel Methods in Molecular and Cellular Biochemistry of Muscle. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-6353-2_16.

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Smith, Stephen J., Luis R. Osses, and George J. Augustine. "Fura-2 Imaging of Localized Calcium Accumulation Within Squid ‘Giant’ Presynaptic Terminal." In Calcium and Ion Channel Modulation. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0975-8_12.

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Johnson, Martin. "Calcium Imaging of Store-Operated Calcium (Ca2+) Entry (SOCE) in HEK293 Cells Using Fura-2." In Calcium Signalling. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9018-4_15.

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Wiltink, Anneke, Arnoud van der Laarse, Nel P. M. Herrmann-Erlee, Joke M. van der Meer, and Dirk L. Ypey. "The Use of the Fluorescent Probe Fura-2 For Intracellular Free Calcium Measurements: Some Methodological Aspects." In Biotechnology Applications of Microinjection, Microscopic Imaging, and Fluorescence. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2828-9_16.

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Hayes, Brendan A., P. V. Avdonin, and U. S. Ryan. "MAG-FURA-2 Elicited Fluorescent Response of Subcellular Magnesium in Endothelial Cells: A Sharp Contrast with Calcium." In Vascular Endothelium. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3736-6_35.

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Conference papers on the topic "Furo[2"

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Khvatov, Ivan A., Alexander N. Kharitonov, and Alexey Yu Sokolov. "FERRETS MAY LEARN AWARENESS IF THEIR OWN BODY LIMITS." In International Psychological Applications Conference and Trends. inScience Press, 2021. http://dx.doi.org/10.36315/2021inpact105.

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"The study of the ability of self-awareness (self-awareness, the ability to perceive one's own body and mental properties separately from objects of the external world) in animals contributes to the study of the specifics of human consciousness. One of the aspects of self-awareness is body-awareness, which is expressed in the ability of an animal to take into account the physical parameters of its body when regulating behavior. We studied the ability of ferrets (Mustela putorius furo) to be aware of the limits of their own bodies. To solve the experimental problem, the animals had to choose ho
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Đermanović, Mirjana, Ljubica Bojanić, Vesna Rudić-Grujić, and Vesna Petković. "Patulin as a risk factor in a children's food." In Proceedings of the International Congress Public Health - Achievements and Challenges. Institute of Public Health of Serbia "Dr Milan Jovanović Batut", 2024. http://dx.doi.org/10.5937/batutphco24077d.

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Background: Patulin (4-hydroxy-4H-furo[3,2-c]pyran-2(6H)-one; CAS Number 149-29-1) patulin as a secondary metabolite of certain types of molds, primarily Penicillium, Aspergillus and Byssochlamys, belongs to the group of mycotoxins. Patulin is a well-known toxicant in food, with adverse immunological, neurological and gastrointestinal outcomes associated with chronic intake. Patulin is an enteropathogenic mycotoxin and has the ability to alter the function of the intestine. Methods and Objectives: The method for determining patulin using liquid chromatography is described in AOAC method 995.10
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Poll, C. T., and J. Westwick. "THE ROLE OF IONISED INTRACELLULAR FREE CALCIUM ([Ca++]i) IN THROMBIN-INDUCED DENSE GRANULE SECRETION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644475.

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Fura 2 is one of a recently-introduced family of Ca++ indicators with improved fluorescent properties compared to quin 2 (Grynkiewicz et al 1985). This study has examined the role of [Ca++]i in thrombin-induced dense granule release using prostacyclin-washed human platelets loaded with either thedense granule marker 14C-5HT (5HT) alone or with 5HT together with quin 2 ([quin2]i = 0.8mM) or fura 2 ([fura 2]i 20-30µM). In the presence of ImM extracellular calcium concentration ([Ca++]i) the [Ca++]e in quin 2 and fura 2 loaded platelets was 93±2 (n=10 experiments) and 133±0.3nM (n=12 experiments)
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Kribben, A., E. Fritschka, M. Sibold, M. Fassbender, A. Distler, and Th Philipp. "EFFECT OF FUROSEMIDE ON PLATELET AGGREGATION AND ON ALPHA-ADRENOCEPTOR-DENSITY IN MAN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643447.

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Furosemide (FUR) reduces the ∝2-adrenoceptor- (∝2-R) mediated pressor effect of norepinephrine. Since it has been shown that FUR reduces platelet aggregation ( AGG) we studied the effect of FUR on α2-R as well as that on the ∝2-R-medi ated epinephrine ( EPI)-induced AGG a) ex vivo and b) in vitro. For comparison the effect of FUR on ADP-induced AGG was also studied. Methods: a) 8 normotensive men received FUR (30 mg b. i.d. ) for 3 weeks. EPI- (1 μmol/1) and ADP- (1 μmol/1) induced platelet AGG were measured before as well as after 3 weeks of FUR application with a semiautomatic device ( APACT
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Koyama, M., F. Katabami, K. Matsuno, et al. "THROMBIN-INDUCED BIPHASIC Ca2+TRANSIENT DETECTED BY FURA-2 FLUORESCENCE WAS COUPLED WITH BIPHASIC Ca2+ UPTAKE IN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644476.

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In the last congress on Thrombosis and Haemostasis in SanDiego we presented the biphasic Ca2+transient in thrombin-stimulated platelets detected by quin2. This time we tried to measure Ca2+ transient in platelets using other Ca2+indicators such as fura-2 and aequorin. In order to evaluate the contribution of increased Ca2+ influx across the plasma-membrane in elevating cytosolic free Ca concentration on platelet activation, 45 Ca2+uptake was measured simultaneouslyby silicon-oil centrifugation method with or without 5 mM EGTA treatment. Such EGTA treatment was intended to remove the entire 45C
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Lanza, F., A. Beretz, M. Kubina, and J.-P. Cazenave. "INCREASED AGGREGATION AND SECRETION RESPONSES OF HUMAN PLATELETS WHEN LOADED WITH THE CALCIUM FLUORESCENT PROBES QUIN2 AND FURA-2." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643760.

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Incubation of human platelets with the fluorescent dye esters quin2-AM (10 μM) or fura-2-AM (1 μM) makes possible the direct measurement of intracellular free calcium ([Ca2+1).Underthese conditions, basal levels of [Ca2+]i of 120 ± 16 nM (n=23) using quin2 and 137 ± 15 nM (n=5) using fura-2 can be measured. Both probes record comparable increases of [Ca2 ]i after stimulation with ADP, thrombin, PAF, or U-46619. Incorporation into human platelets of quin2 or fura-2 at the concentrations used to monitor [Ca2+]i leads to the activation of platelets. This was shown by increased aggregation and sec
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Van den Bergh, Viviane, Katrien Meuwis, Noel Boens, et al. "Photophysical study of the Ca2+ indicator Fura-2 and the K+ indicator PBFI." In OE/LASE '94, edited by Joseph R. Lakowicz. SPIE, 1994. http://dx.doi.org/10.1117/12.182705.

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Watts, I. S., R. J. Keery, and P. Lumlev. "EFFECT OF EXTRACELLULAR Ca2+ UPON AGONIST-INDUCED Ca2+ TRANSIENTS IN HUMAN PLATELETS: COMPARISON OF QUIN 2 AND FURA 2." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644525.

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In human platelets loaded with the Ca2+ indicator Quin 2 (Q2), elevated cytosolic Ca2+ ([Ca2+]i) induced by platelet agonists is greatly attenuated in the absence of extracellular Ca2+ ([Ca2+]o), suggesting the majority of [Ca2+]i is derived via transmembrane influx. However, the relatively weak fluorescent properties of Q2 require that high intraplatelet concentrations be used which may influence [Ca2+]i homeostasis and platelet function. This is less of a problem with the more intensely fluorescent Ca2+-indicator Fura 2 (F2). We have compared the rise in [Ca2+]i and aggregation induced by a
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Rao, Gundu H. R., and James G. White. "INFLUENCE OF CALCIUM FLUX ON STABILITY OF PLATELET MICROTUBULE COILS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643904.

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Resting human platelets have a characteristic discoid form supported by a circumferential microtubule (MT). Ultrastructural, immunocytochemical and immunofluorescence studies have shown that the circumferential MT is a stable structure which undergoes constriction following exposure of platelets to aggregating agents. However, some biochemical and morphological studies suggested that MT coils dissolved almost completely within seconds after exposure to aggregating agents, then reassembled 1-4 minutes later. One investigation suggested that disappearance of the MT coils was associated with calc
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Gangjee, Aleem, Xin Zhang, Ojas Namjoshi, Ravi Kumar Vyas Devambatla, Ernest Hamel та Susan L. Mooberry. "Abstract 3244: Design, synthesis and biological evaluation of substituted furo[2,3-d]pyrimidines as potent microtubule targeting antitumor agents that circumvent Pgp and βIII-tubulin mediated resistance". У Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3244.

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Reports on the topic "Furo[2"

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Philosoph-Hadas, Sonia, Richard Crain, Shimon Meir, Nehemia Aharoni, and Susan Lurie. Calcium-Mediated Signal Transduction during Leaf Senescence. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604925.bard.

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We have examined the possibility that modulation of [Ca2+]cyt may represent a signal which induces senescence processes in leaves, through triggering of lipid hydrolysis leading to the cascade of detriorative events. Characterization of the signal transduction components operating during leaf senescence was gained by studying various Ca2+-dependent activities of parsley and chrysanthemum leaves, in relation to several senescence functions, and in response to senescence-modulating hormones (ethylene,ABA, BA and IAA). Some innovative findings regarding the control of senescence processes by [Ca2
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Jocelyn, Sabrina, Élise Ledoux, Damien Burlet-Vienney, et al. Identification en laboratoire des éléments essentiels au processus d’intégration sécuritaire de cellules cobotiques. IRSST, 2024. http://dx.doi.org/10.70010/qkwy4060.

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Les cobots sont apparus vers 2010 en industrie et les accidents sont très peu documentés. La gestion des risques en cobotique représente un réel défi. La littérature scientifique montre l’existence de divers modèles, méthodes et outils pour gérer les risques en cobotique, en mettant l’opérateur humain au cœur de l’intégration des applications collaboratives. Cependant, un autre humain clé de la mise en œuvre de ces applications est négligé la plupart du temps. Il s’agit de l’intégrateur, celui qui doit concevoir la cellule cobotique. À notre connaissance, deux études portant sur un même projet
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