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Journal articles on the topic 'Furoquinolines'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Fayol, Aude, and Jieping Zhu. "Synthesis of Furoquinolines by a Multicomponent Domino Process." Angewandte Chemie International Edition 41, no. 19 (2002): 3633–35. http://dx.doi.org/10.1002/1521-3773(20021004)41:19<3633::aid-anie3633>3.0.co;2-t.

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2

Paira, Rupankar, Tarique Anwar, Maitreyee Banerjee, et al. "Copper–phenanthroline catalysts for regioselective synthesis of pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]furoquinolines/phenanthrolines and of pyrrolo[1,2-a]phenanthrolines under mild conditions." Beilstein Journal of Organic Chemistry 10 (March 20, 2014): 692–700. http://dx.doi.org/10.3762/bjoc.10.62.

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A new series of pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]furoquinolines/phenanthrolines and pyrrolo[1,2-a]phenanthrolines were efficiently built up from an 8-hydroxyquinoline derivative or phenanthroline via 1,3-dipolar cycloaddition reaction involving non-stabilized azomethine ylides, generated in situ from the parent furo[3,2-h]quinoliniums/phenanthroliums, in presence of a copper(II) chloride–phenanthroline catalytic system. The methodology combines general applicability with high yields.

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3

Chen, Keh-Shaw, Ya-Ling Chang, Che-Ming Teng, Chieh-Fu Chen, and Yang-Chang Wu. "Furoquinolines with Antiplatelet Aggregation Activity from Leaves ofMelicope confusa." Planta Medica 66, no. 01 (2009): 80–81. http://dx.doi.org/10.1055/s-0029-1243116.

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4

Ferreira, Maria Elena, Antonieta Rojas de Arias, Gloria Yaluff, et al. "Antileishmanial activity of furoquinolines and coumarins from Helietta apiculata." Phytomedicine 17, no. 5 (2010): 375–78. http://dx.doi.org/10.1016/j.phymed.2009.09.009.

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5

Savina, S. A., V. M. Lyubchanskaya, L. M. Alekseeva, A. S. Shashkov, and V. G. Granik. "Synthesis of novel furoquinolines and furobenzodiazepines from tetronic acid." Russian Chemical Bulletin 56, no. 11 (2007): 2298–304. http://dx.doi.org/10.1007/s11172-007-0363-y.

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6

Chosson, Elizabeth, Anne-Emmanuelle Hay, Angele Chiaroni, et al. "Sarcodifurines A and B, Two New Furoquinolines from Sarcomelicope follicularis." HETEROCYCLES 63, no. 9 (2004): 2043. http://dx.doi.org/10.3987/com-04-10146.

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7

Kumar, Devadoss Karthik, Rayappan Rajkumar, and Subramaniam Parameswaran Rajendran. "Robust synthesis of linear and angular furoquinolines using Rap–Stoermer reaction." Chemistry of Heterocyclic Compounds 52, no. 5 (2016): 322–25. http://dx.doi.org/10.1007/s10593-016-1885-8.

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8

Mahesh, M., Ch Venkateshwar Reddy, K. Srinivasa Reddy, P. V. K. Raju, and V. V. Narayana Reddy. "Imino Diels–Alder Reactions: Efficient Synthesis of Pyrano and Furoquinolines Catalyzed by ZrCl4." Synthetic Communications 34, no. 22 (2004): 4089–104. http://dx.doi.org/10.1081/scc-200036586.

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9

Cheng, Juei-Tang, Tzen Kwan Chang, and Ih-Sheng Chent. "Skimmianine and related furoquinolines function as antagonists of 5-hydroxytryptamine receptors in animals." Journal of Autonomic Pharmacology 14, no. 5 (1994): 365–74. http://dx.doi.org/10.1111/j.1474-8673.1994.tb00617.x.

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10

Paulini, Hubert, Reiner Waibel, and Oskar Schimmer. "Mutagenicity and structure-mutagenicity relationships of furoquinolines, naturally occurring alkaloids of the Rutaceae." Mutation Research Letters 227, no. 3 (1989): 179–86. http://dx.doi.org/10.1016/0165-7992(89)90043-2.

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11

Neville, Charles F., Michael F. Grundon, Venkataraman N. Ramachandran, Geisla Reisch, and Johannes Reisch. "Quinoline alkaloids. Part 28. The biosynthesis of furoquinolines and other hemiterpenoids in Ptelea trifoliata." Journal of the Chemical Society, Perkin Transactions 1, no. 9 (1991): 2261. http://dx.doi.org/10.1039/p19910002261.

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12

Gharib, Ali, and Manouchehr Jahangir. "Catalytic Synthesis of Pyrano- and Furoquinolines Using Nano Silica Chromic Acid at Room Temperature." Organic Chemistry International 2013 (June 17, 2013): 1–7. http://dx.doi.org/10.1155/2013/693763.

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Nano silica chromic acid (nano-SCA) is found to catalyze efficiently the three component-coupling reactions of aldehydes, amines, and cyclic enol ethers such as 3,4-dihydro-2H-pyran and 2,3-dihydrofuran under mild conditions to afford the corresponding pyrano- and furanoquinolines in excellent yields with high endoselectivity. Interestingly, 2,3-dihydrofuran afforded selectively endoproducts under the similar reaction conditions. Heterogeneous reaction conditions, easy procedure, short reaction time, and high yields are some important advantages of this method.

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13

Nganou, Blaise Kemajou, Armelle T. Mbaveng, Serge A. T. Fobofou, et al. "Furoquinolines and dihydrooxazole alkaloids with cytotoxic activity from the stem bark of Araliopsis soyauxii." Fitoterapia 133 (March 2019): 193–99. http://dx.doi.org/10.1016/j.fitote.2019.01.003.

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14

Barluenga, José, Abraham Mendoza, Félix Rodríguez, and Francisco J Fañanás. "Synthesis of Furoquinolines by a One-Pot Multicomponent Cascade Reaction Catalyzed by Platinum Complexes." Chemistry - A European Journal 14, no. 35 (2008): 10892–95. http://dx.doi.org/10.1002/chem.200802146.

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15

Ravindranath, N., C. Ramesh, M. Ravinder Reddy, and Biswanath Das. "A Facile and Convenient Three-component Coupling Protocol for the Synthesis of Pyrano and Furoquinolines." Chemistry Letters 32, no. 3 (2003): 222–23. http://dx.doi.org/10.1246/cl.2003.222.

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16

Das, Biswanath, M. Ravinder Reddy, V. Saidi Reddy, and R. Ramu. "Novel and Efficient Lewis Acids as Catalysts for Single-step Synthesis of Pyrano- and Furoquinolines." Chemistry Letters 33, no. 11 (2004): 1526–27. http://dx.doi.org/10.1246/cl.2004.1526.

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17

Nebois, Pascal, Houda Fillion, Leila Benameur, Bernard Fenet, and Jean-Louis Luche. "Synthesis and NMR structural study of furoquinolines and naphthofurans from quinones and a 1-azadiene." Tetrahedron 49, no. 43 (1993): 9767–74. http://dx.doi.org/10.1016/s0040-4020(01)80179-4.

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18

Yadav, Jhillu S., Basi V. Subba Reddy, Chinti Rheddy Madhuri, and Gowravaram Sabitha. "ChemInform Abstract: LiBF4-Catalyzed Imino-Diels-Alder Reaction: A Facile Synthesis of Pyrano- and Furoquinolines." ChemInform 32, no. 39 (2010): no. http://dx.doi.org/10.1002/chin.200139159.

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19

Bouma, Marinus J., Géraldine Masson, and Jieping Zhu. "Exploiting the Divergent Reactivity of Isocyanoacetates: One-Pot Three-Component Synthesis of Functionalized Angular Furoquinolines." European Journal of Organic Chemistry 2012, no. 3 (2011): 475–79. http://dx.doi.org/10.1002/ejoc.201101567.

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20

Bantreil, Xavier, Carine Vaxelaire, Thomas Godet, Evelyne Parker, Carole Sauer, and Philippe Belmont. "Synthesis and reactivity of furoquinolines bearing an external methylene-bond: access to reduced and spirocyclic structures." Organic & Biomolecular Chemistry 9, no. 13 (2011): 4831. http://dx.doi.org/10.1039/c1ob05354j.

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21

Nebois, Pascal, and Houda Fillion. "Reactions of 2-ethoxy-2-butenal N,N-dimethylhydrazone with heterocyclic quinones. Regiospecific formation of furoquinolines." Tetrahedron Letters 32, no. 10 (1991): 1307–10. http://dx.doi.org/10.1016/s0040-4039(00)79652-3.

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22

NEVILLE, C. F., M. F. GRUNDON, V. N. RAMACHANDRAN, G. REISCH, and J. REISCH. "ChemInform Abstract: Quinoline Alkaloids. Part 28. The Biosynthesis of Furoquinolines and Other Hemiterpenoids in Ptelea trifoliata." ChemInform 22, no. 51 (2010): no. http://dx.doi.org/10.1002/chin.199151293.

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23

Das, Biswanath, and K. V. Srinivas. "An Efficient One-Pot Synthesis of Pyrano- and Furoquinolines Employing Two Reusable Solid Acids as Heterogeneous Catalysts." Synlett, no. 10 (2004): 1715–18. http://dx.doi.org/10.1055/s-2004-829576.

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24

Lacroix, Damien, Soizic Prado, Dennis Kamoga, John Kasenene, and Bernard Bodo. "Absolute configuration of 2′(R)-acetylmontrifoline and 2′(R)-montrifoline, furoquinolines from the fruits of Teclea nobilis." Phytochemistry Letters 5, no. 1 (2012): 22–25. http://dx.doi.org/10.1016/j.phytol.2011.08.012.

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25

Bouma, Marinus J., Geraldine Masson, and Jieping Zhu. "ChemInform Abstract: Exploiting the Divergent Reactivity of Isocyanoacetates: One-Pot Three-Component Synthesis of Functionalized Angular Furoquinolines." ChemInform 43, no. 24 (2012): no. http://dx.doi.org/10.1002/chin.201224152.

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26

NEBOIS, P., H. FILLION, L. BENAMEUR, B. FENET, and J. L. LUCHE. "ChemInform Abstract: Synthesis and NMR Structural Study of Furoquinolines and Naphthofurans from Quinones and a 1-Azadiene." ChemInform 25, no. 6 (2010): no. http://dx.doi.org/10.1002/chin.199406058.

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27

Bantreil, Xavier, Carine Vaxelaire, Thomas Godet, Evelyne Parker, Carole Sauer, and Philippe Belmont. "ChemInform Abstract: Synthesis and Reactivity of Furoquinolines Bearing an External Methylene-Bond: Access to Reduced and Spirocyclic Structures." ChemInform 42, no. 48 (2011): no. http://dx.doi.org/10.1002/chin.201148164.

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28

Parker, Evelyne, Nicolas Leconte, Thomas Godet, and Philippe Belmont. "Silver-catalyzed furoquinolines synthesis: from nitrogen effects to the use of silver imidazolatepolymer as a new and robust silver catalyst." Chem. Commun. 47, no. 1 (2011): 343–45. http://dx.doi.org/10.1039/c0cc02623a.

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29

Parker, Evelyne, Nicolas Leconte, Thomas Godet, and Philippe Belmont. "ChemInform Abstract: Silver-Catalyzed Furoquinolines Synthesis: From Nitrogen Effects to the Use of Silver Imidazolate Polymer as a New and Robust Silver Catalyst." ChemInform 42, no. 18 (2011): no. http://dx.doi.org/10.1002/chin.201118133.

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30

Szewczyk, Agnieszka, and Filip Pęczek. "Furoquinoline Alkaloids: Insights into Chemistry, Occurrence, and Biological Properties." International Journal of Molecular Sciences 24, no. 16 (2023): 12811. http://dx.doi.org/10.3390/ijms241612811.

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Furoquinoline alkaloids exhibit a diverse range of effects, making them potential candidates for medicinal applications. Several compounds within this group have demonstrated antimicrobial and antiprotozoal properties. Of great interest is their potential as acetylcholinesterase inhibitors and anti-inflammatory agents in neurodegenerative diseases. The promising biological properties of furoquinoline alkaloids have motivated extensive research in this field. As a result, new compounds have been isolated from this group of secondary metabolites, and numerous pharmacological studies have been co

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31

Gomes, Elsa, Sébastien Travert, Jacqueline Gleye, Claude Moulis, Isabelle Fourasté, and Eduoard Stanislas. "Furoquinoline Alkaloids fromVepris heterophylla." Planta Medica 60, no. 04 (1994): 388. http://dx.doi.org/10.1055/s-2006-959512.

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32

Ravelomanantsoa, Nicole, Philippe Rasoanaivo, and Michel Delmas. "Furoquinoline from Evodia fatraina." Biochemical Systematics and Ecology 23, no. 3 (1995): 339. http://dx.doi.org/10.1016/0305-1978(95)00003-d.

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33

Halstead, Clynton W., Paul I. Forster, and Peter G. Waterman. "Novel Metabolites from the Stem Bark of Brombya sp. Nova (Gap Creek) (Rutaceae)." Natural Product Communications 1, no. 5 (2006): 1934578X0600100. http://dx.doi.org/10.1177/1934578x0600100502.

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Two piperonyl derivatives, seven coumarins and two furoquinoline alkaloids were isolated from the aerial parts of a new species of Brombya [Brombya sp. nov. (Gap Creek) (Rutaceae)]. Three of the compounds were new natural metabolites; 7-(3,4-methylenedioxyphenyl)octene-2-one (7,8-dehydromoskachen D), the coumarin 6-(1ξ,2ξ,3-trihydroxy-3-methylbutyl)-7-hydroxy-2H-1-benzopyran-2-one, and the furoquinoline alkaloid 4,5,6,7-tetramethoxyfuro[2,3-b]quinoline (5,6,7-trimethoxydictamnine). The secondary metabolites isolated in this study are typical of the Rutaceae, contrasting with earlier studies on

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34

Sun, Jianbo, Neng Jiang, Mengying Lv, et al. "Anstifolines A and B, two dimeric furoquinoline alkaloids from the root bark of Dictamnus angustifolius." RSC Advances 6, no. 27 (2016): 22550–54. http://dx.doi.org/10.1039/c5ra26460j.

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35

M., A. ASHROF, and S. RAMAN P. "Facile Rearrangement of a Furoquinoline." Journal of Indian Chemical Society Vol. 69, Oct 1992 (1992): 690–91. https://doi.org/10.5281/zenodo.6022741.

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36

Szewczyk, Agnieszka, Mariusz Grabowski, and Dominika Zych. "Ruta chalepensis L. In Vitro Cultures as a Source of Bioactive Furanocoumarins and Furoquinoline Alkaloids." Life 13, no. 2 (2023): 457. http://dx.doi.org/10.3390/life13020457.

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Recently, due to the decreasing areas of cultivation and climate change, the use of biotechnological methods to obtain biomass, which is a source of valuable bioactive metabolites, is becoming more and more interesting. In this study, Ruta chalepensis in vitro cultures were investigated in RITA® temporary immersion bioreactors. Biomass growth and the production of secondary metabolites in 4- and 5-week growth cycles on three variants of the Linsmaier and Skoog (LS) medium (naphthyl-1-acetic acid/6-benzylaminopurine (NAA/BAP): 0.5/1.0, 0.1/0.1, and 1.0/1.0 mg/L) were analyzed. Using high-perfor

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37

Al-Rehaily, Adnan J., Mohammad S. Ahmad, Ilias Muhammad, Assad A. Al-Thukair, and Herman P. Perzanowski. "Furoquinoline alkaloids from Teclea nobilis." Phytochemistry 64, no. 8 (2003): 1405–11. http://dx.doi.org/10.1016/j.phytochem.2003.09.013.

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38

Lv, Mengying, Yuan Tian, Zunjian Zhang, Jingyu Liang, Fengguo Xu, and Jianbo Sun. "Plant metabolomics driven chemical and biological comparison of the root bark of Dictamnus dasycarpus and Dictamnus angustifolius." RSC Advances 5, no. 20 (2015): 15700–15708. http://dx.doi.org/10.1039/c5ra00115c.

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The chemical and biological differences between Dictamnus dasycarpus and Dictamnus angustifolius have been compared in this study. Among all chemical markers, furoquinoline alkaloids may play a major role in the bioactivities of these two plants.

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39

Bhoga, Umadevi, R. S. Mali, and Srinivas R. Adapa. "New synthesis of linear furoquinoline alkaloids." Tetrahedron Letters 45, no. 51 (2004): 9483–85. http://dx.doi.org/10.1016/j.tetlet.2004.09.041.

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40

Komala, Ismiarni, Mawardi Rahmani, Mohd Aspollah Sukari, Hazar Bebe Mohd Ismail, Gwendoline Ee Cheng Lian, and Asmah Rahmat. "Furoquinoline alkaloids fromMelicope bonwickii(F.Muell.) T.Hartley." Natural Product Research 20, no. 4 (2006): 355–60. http://dx.doi.org/10.1080/14786410500462983.

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41

Kumar, Manoj, Lokesh Kumar Kumawat, Vinod Kumar Gupta, and Anuj Sharma. "Rational design of the first furoquinolinol based molecular systems for easy detection of Cu2+with potential applications in the area of membrane sensing." RSC Advances 5, no. 128 (2015): 106030–37. http://dx.doi.org/10.1039/c5ra21862d.

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42

Striegel, Hans-Günter, and Wolfgang Wiegrebe. "5,13-Diethyl-10-methyl-8-heptadecanone: A component of post-1976 Kelex 100." Collection of Czechoslovak Chemical Communications 56, no. 10 (1991): 2203–8. http://dx.doi.org/10.1135/cccc19912203.

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The title compound was prepared by mixed aldol condensation of 2-ethylhexanal and acetone, double bond hydrogenation, aldol autocondensation of the resulting saturated ketone and finel double bond hydrogenation. It is identical with the ketone C22H44O previously isolated from new Kelex 100 which was erroneously assigned a furoquinoline structure.

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43

R., A. PAWAR, B. BAJARE P., and B. MUNDADE S. "Studies on Vilsmeier-Haack Reaction. A New Route to 2-Chloroquinoline-3-carboxyaldehydes and a Furoquinoline Derivative." Journal of Indian Chemical Society Vol. 67, Aug 1990 (1990): 685–86. https://doi.org/10.5281/zenodo.6243859.

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Department of Chemistry,S.S V.P. Sanstha's Late Karmveer Dr. P.R. Ghogrey Science College, Dhule·424 005 <em>Manuscript received 5 October 1989, revised 30 March 1990. accepted 11 May 1990</em> Studies on Vilsmeier-Haack Reaction. A New Route to 2-Chloroquinoline-3-carboxyaldehydes and a Furoquinoline Derivative  

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44

Li, Shuo-Guo, Hai-Yan Tian, Wei-Cai Ye, and Ren-Wang Jiang. "Benzopyrans and furoquinoline alkaloids from Melicope pteleifolia." Biochemical Systematics and Ecology 39, no. 1 (2011): 64–67. http://dx.doi.org/10.1016/j.bse.2011.01.005.

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45

Schimmer, Oskar, and Irmgard Kühne. "Furoquinoline alkaloids as photosensitizers in Chlamydomonas reinhardtii." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 249, no. 1 (1991): 105–10. http://dx.doi.org/10.1016/0027-5107(91)90136-c.

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46

Kang, Sam Sik, and Won Sick Woo. "Furoquinoline alkaloids from the leaves ofMelicope confusa." Archives of Pharmacal Research 9, no. 1 (1986): 11–13. http://dx.doi.org/10.1007/bf02857699.

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47

ASHROF, M. A., and P. S. RAMAN. "ChemInform Abstract: Facile Rearrangement of a Furoquinoline." ChemInform 25, no. 11 (2010): no. http://dx.doi.org/10.1002/chin.199411162.

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48

Szewczyk, Agnieszka, Monika Trepa, and Dominika Zych. "Optimization of the Production of Secondary Metabolites from Furanocoumarin and Furoquinoline Alkaloid Groups in In Vitro Ruta corsica Cultures Grown in Temporary Immersion Bioreactors." Molecules 29, no. 22 (2024): 5261. http://dx.doi.org/10.3390/molecules29225261.

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Ruta corsica is a rare and endemic plant native to Corsica. Due to its limited distribution and the priority to preserve natural sites, has been insufficiently studied. In vitro cultures provide an opportunity to research R. corsica under controlled conditions. In the present study, in vitro cultures of R. corsica were conducted in PlantformTM bioreactors. The study aimed to assess the effects of growth cycle length (5 and 6 weeks) and different concentrations of plant growth regulators (NAA and BAP) at 0.1/0.1, 0.1/0.5, 0.5/0.5, 0.5/1.0, and 1.0/1.0 mg/L on biomass growth and secondary metabo

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49

Wahjoedi, Ryan Ayub, Ratih Dewi Saputri, Tjitjik Srie Tjahjandarie, and Mulyadi Tandjung. "Melicope moluccana Antimalarial Activity of Furoquinoline Alkaloids from the Leaves of Melicope moluccana." Journal of Tropical Pharmacy and Chemistry 5, no. 2 (2020): 138–42. http://dx.doi.org/10.25026/jtpc.v5i2.260.

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Two furoquinoline alkaloids, leptanoine C (1) and haplopine-3,3´-dimethylallyl ether (2) were isolated from the leaves of Melicope moluccana. The chemical structure of both compounds was determined based on spectroscopic data, including UV, IR, HR-ESI-MS, 1D, and 2D NMR spectral data. The antimalarial activity of compounds 1-2 against Plasmodium falciparum 3D7 showing their IC50 values are 0.18 ppm and 2.28 µg/mL, respectively.

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50

Cironi, Pablo, Judit Tulla-Puche, George Barany, Fernando Albericio, and Mercedes Álvarez. "Solid-Phase Syntheses of Furopyridine and Furoquinoline Systems." Organic Letters 6, no. 9 (2004): 1405–8. http://dx.doi.org/10.1021/ol049762f.

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