Academic literature on the topic 'Hydroxyindoles'

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Journal articles on the topic "Hydroxyindoles"

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Lee, Jintae, Tarun Bansal, Arul Jayaraman, William E. Bentley, and Thomas K. Wood. "Enterohemorrhagic Escherichia coli Biofilms Are Inhibited by 7-Hydroxyindole and Stimulated by Isatin." Applied and Environmental Microbiology 73, no. 13 (2007): 4100–4109. http://dx.doi.org/10.1128/aem.00360-07.

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ABSTRACT Since indole is present at up to 500 μM in the stationary phase and is an interspecies biofilm signal (J. Lee, A. Jayaraman, and T. K. Wood, BMC Microbiol. 7:42, 2007), we investigated hydroxyindoles as biofilm signals and found them also to be nontoxic interspecies biofilm signals for enterohemorrhagic Escherichia coli O157:H7 (EHEC), E. coli K-12, and Pseudomonas aeruginosa. The genetic basis of EHEC biofilm formation was also explored, and notably, virulence genes in biofilm cells were repressed compared to those in planktonic cells. In Luria-Bertani medium (LB) on polystyrene with
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Morton, D. J. "Methoxyindole production by the pineal gland appears to be dependent on the concentration of hydroxy precursors and their affinity for hydroxyindole-O-methyltransferase." Journal of Endocrinology 111, no. 1 (1986): 133–36. http://dx.doi.org/10.1677/joe.0.1110133.

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ABSTRACT Various pineal gland indole metabolites were separated by thin-layer chromatography after organ culture with tritiated serotonin. The amounts of methoxyindoles produced were remarkably constant and female rats in oestrus appeared to produce greater amounts than male rats. The results show a correlation between methylation and the concentration and affinity of the various hydroxyindoles for hydroxyindole-O-methyltransferase. J. Endocr. (1986) 111, 133–136
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Chirkova, Zhanna V. "SYNTHESIS OF N-HYDROXYINDOLES." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENIY KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 60, no. 4 (2017): 4. http://dx.doi.org/10.6060/tcct.2017604.5560.

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The basic synthetic methods for obtaining N-hydroxyindoles were studied. The first method is intramolecular reductive cyclization of ortho-substituted nitroaromatic compounds by various reducing agents. Nitrophenyl acetaldehydes (synthesis by Acheson), N,N-disubstituted amino-2-nitrostyrenes (synthesis by Somei), ortho-nitroketoetheres of different structure or 1-(o-nitroarene)-1-cyanoalkylnitroketones, ortho-nitrophenylacetonitriles were used as substrates for the synthesis of N-hydroxyindoles. Titanium chloride (III), zinc in THF solution of ammonium chloride or in acetic acid, stannous chlo
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RAGHAVENDRA, G. JOSHI, S. GADAGINAMATH GURU, and G. PUJAR BASAYYA. "Synthesis and Antimicrobial Activity of some New 4-Isogramines, 4-Arylthiomethyl and 4-Arylazo Derivatives of 5-Hydroxyindoles." Journal of Indian Chemical Society Vol. 71, April 1994 (1994): 175–78. https://doi.org/10.5281/zenodo.5894221.

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Department of Chemistry, Karnatak. University, Dharwad-580 003 <em>Manuscript received 22 March 1993. accepted 3 June 1993</em> Mannich reaction of 5-hydroxyindoles (1-10) .with formaldehyde and secondary amines produced the 4-isogramines (11-48). The nucleophilic displacement of dimethylamine from 4-dimethylaminomethyl-5-hydroxyindoles (11-15) was effected by heating them with thiophenols to get 4-arylthiomethyl-5-hydroxyindoles (49-58). The treatment of 5-hydroxyindoles (1-4 and 6-9) with aryldiazonium salt solution afforded exclusively 4-arylazo-5-hydroxyindoles (59-74). All the compounds w
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Yamazaki, Yoshimitsu, and Yasuhiro Kawano. "Inhibitory Effect of Hydroxyindoles and their Analogues on Human Melanoma Tyrosinase." Zeitschrift für Naturforschung C 65, no. 1-2 (2010): 49–54. http://dx.doi.org/10.1515/znc-2010-1-209.

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A recent study showed that N-acylserotonin derivatives have strong inhibitory activity against tyrosinase. To clarify the role of the 5-hydroxy group in the indole ring, 2-, 4-, 5-, 6-, and 7-hydroxyindole and 11 related compounds such as 5-hydroxyindan and 6-hydroxyquinoline were tested for their inhibition of catecholase activity of tyrosinase from human HMVII melanoma cells. 6-Hydroxyindole (5) and 7-hydroxyindole (6) were potent inhibitors, while 5-hydroxyindole (4) was a weaker inhibitor than the above-mentioned compounds (IC50 = 20, 79, 366, and 342 μM for 5, 6, 4, and kojic acid, respec
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Somei, Masanori. "1-Hydroxyindoles." HETEROCYCLES 50, no. 2 (1999): 1157. http://dx.doi.org/10.3987/rev-98-sr(h)8.

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Kikugawa, Yasuo, Toshiyuki Henmi, and Takeshi Sakamoto. "A New Synthesis of 1-Hydroxyindoles and Spectra of 1-Hydroxyindole." HETEROCYCLES 44, no. 1 (1997): 157. http://dx.doi.org/10.3987/com-95-s2.

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Morton, D. J. "Hydroxyindole-O-methyltransferase catalyses production of methoxyindoles in rat pineal gland dependent on the concentration of hydroxy precursors and their affinity for the enzyme." Journal of Endocrinology 115, no. 3 (1987): 455–58. http://dx.doi.org/10.1677/joe.0.1150455.

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ABSTRACT Indole metabolites were separated by thin-layer chromatography following organ culture of rat pineal glands with tritiated tryptophan. Methoxyindole production was shown to differ substantially from results obtained when pineal glands were incubated with radiolabelled serotonin. The correlation between hydroxy- and corresponding methoxyindoles was, however, remarkably similar to previous results, and indicated that in the pineal gland, it is probable that production of methoxyindoles is dependent on the concentration of the various hydroxyindoles and their relative affinities for hydr
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HENMI, T., T. SAKAMOTO, and Y. KIKUGAWA. "ChemInform Abstract: A New Synthesis of 1-Hydroxyindoles and Spectra of 1-Hydroxyindole." ChemInform 28, no. 21 (2010): no. http://dx.doi.org/10.1002/chin.199721127.

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Hanuszewska, Maria, Magdalena Prusik, and Bogdan Lewczuk. "Embryonic Ontogeny of 5-Hydroxyindoles and 5-Methoxyindoles Synthesis Pathways in the Goose Pineal Organ." International Journal of Molecular Sciences 20, no. 16 (2019): 3948. http://dx.doi.org/10.3390/ijms20163948.

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The aim of this study was to characterize the embryonic ontogeny of 5-hydroxyindoles and 5-methoxyindoles synthesis pathways in the goose pineal organ. The study was performed on embryos aged 14–28 days, which have been incubated under a 12L:12D cycle. The pineal organs were collected for measurements of indole content by HPLC every 6 h on embryonic day (ED) 14, ED 16, ED 18 and ED 22 or every 2 h on ED 24, ED 26 and ED 28. The level of tryptophan showed no significant changes during development and no day-night variations. The content of 5-hydroxytryptophan increased between ED 14 and ED 26.
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Dissertations / Theses on the topic "Hydroxyindoles"

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Effroy, Jean-Louis. "Tentative de détermination des hydroxyindoles par pulsovoltamétrie." Paris 5, 1991. http://www.theses.fr/1991PA05P059.

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Becker, Martin. "Darstellung und Umwandlung von 1-Hydroxyindolin-2-onen." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=980955041.

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Estrada, Anthony Armando. "I, Studies directed towards the total synthesis of nocathiacin III II, the development of a new synthetic technology for the construction of N-hydroxyindoles and synthesis of nocathiacin model systems ; III, the development of a mild and selective method for the hydrolysis of esters with trimethyltin hydroxide ; IV, contributions towards the total synthesis of thiostrepton /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3321980.

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Thesis (Ph. D.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed September 3, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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Becker, Martin [Verfasser]. "Darstellung und Umwandlung von 1-Hydroxyindolin-2-onen / von Martin Becker." 2006. http://d-nb.info/980955041/34.

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Němečková, Anna. "Voltametrické a amperometrické stanovení homovanilové, vanilmandlové a 5-hydroxy-3-indoloctové kyseliny." Doctoral thesis, 2020. http://www.nusl.cz/ntk/nusl-434498.

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Presented dissertation thesis is focused on the development of electrochemical methods for the determination of three important tumour biomarkers, namely homovanillic acid (HVA), vanillylmandelic acid (VMA), and 5-hydroxyindole-3-acetic acid (5-HIAA). First part of the study is focused on electrochemical behaviour of these analytes in batch arrangement using differential pulse voltammetry (DPV) at screen-printed carbon electrodes (SPCEs). It has been proved that presented method is sufficiently sensitive for monitoring above mentioned analytes. Moreover, it can be used for determination of HVA
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Books on the topic "Hydroxyindoles"

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Yang, Jimmy Chen. Discovery, synthesis, and steps toward target identification of the novel 2-amino-3-hydroxyindole anti-malaria drug class. 2009.

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2

Hanneken, Ludger. Einfluss von variationen des erdmagnetfeldes (EMF) auf die aktivität der hydroxyindol-D-methyltransferase und N-acetyltransferase in retina und pinealorgan von hühnerembryonen. 1986.

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Book chapters on the topic "Hydroxyindoles"

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Spande, Thomas F. "Hydroxyindoles, Indole Alcohols, and Indolethiols." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186947.ch1.

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Bährle-Rapp, Marina. "Hydroxyindole." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_5061.

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Iizuka, Hideaki, Takayuki Ishige, Yuri Ohta, and Takehiko Yajima. "Simultaneous Determination of 5-Hydroxyindoles and Catecholamines by Hplc with Fluorometric Precolumn Derivatization." In Advances in Experimental Medicine and Biology. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4709-9_104.

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Moroni, Flavio, Raffaella Carpenedo, Guido Mannaioni, et al. "Studies on the Pharmacological Properties of Oxindole (2-Hydroxyindole) and 5-Hydroxyindole: Are They Involved in Hepatic Encephalopathy?" In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5945-0_4.

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Winkelmann, Jochen. "Diffusion coefficient of 5-hydroxyindole-3-acetic acid in water." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_709.

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Milovanović, D. D., N. Majkić-Sing, D. Mirković, and J. Pavlović. "Plasma and Urinary Serotonin and 5-Hydroxyindol-3-Acetic Acid in Adults with Migraine and Tension-Type Headache." In Advances in Experimental Medicine and Biology. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4709-9_25.

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Davison, A. S., B. Norman, A. M. Milan, et al. "Assessment of the Effect of Once Daily Nitisinone Therapy on 24-h Urinary Metadrenalines and 5-Hydroxyindole Acetic Acid Excretion in Patients with Alkaptonuria After 4 Weeks of Treatment." In JIMD Reports. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/8904_2017_72.

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Acheson, R. Morrin. "1-Hydroxypyrroles, 1-Hydroxyindoles and 9-Hydroxycarbazoles." In Advances in Heterocyclic Chemistry Volume 51. Elsevier, 1990. http://dx.doi.org/10.1016/s0065-2725(08)60002-1.

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Somei, Masanori. "Recent advances in the chemistry of 1-hydroxyindoles, 1-hydroxytryptophans, and 1-hydroxytryptamines." In Advances in Heterocyclic Chemistry. Elsevier, 2002. http://dx.doi.org/10.1016/s0065-2725(02)82027-x.

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"Nenitzescu 5-Hydroxyindole Synthesis." In Indole Ring Synthesis. John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118695692.ch15.

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